CN107304398A - A kind of preparation technology for the Cordyceps militaris magma product for improving immunity - Google Patents
A kind of preparation technology for the Cordyceps militaris magma product for improving immunity Download PDFInfo
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- CN107304398A CN107304398A CN201710323091.6A CN201710323091A CN107304398A CN 107304398 A CN107304398 A CN 107304398A CN 201710323091 A CN201710323091 A CN 201710323091A CN 107304398 A CN107304398 A CN 107304398A
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- extract
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- cordyceps militaris
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12G—WINE; PREPARATION THEREOF; ALCOHOLIC BEVERAGES; PREPARATION OF ALCOHOLIC BEVERAGES NOT PROVIDED FOR IN SUBCLASSES C12C OR C12H
- C12G3/00—Preparation of other alcoholic beverages
- C12G3/04—Preparation of other alcoholic beverages by mixing, e.g. for preparation of liqueurs
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/062—Ascomycota
- A61K36/066—Clavicipitaceae
- A61K36/068—Cordyceps
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/39—Convolvulaceae (Morning-glory family), e.g. bindweed
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- Alternative & Traditional Medicine (AREA)
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- Wood Science & Technology (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The invention discloses a kind of preparation technology for the Cordyceps militaris magma product for improving immunity, it is related to technical field of medicine preparation, comprises the following steps:1)Cordyceps militaris is crushed to 100 mesh, plus 20% edible alcohol of 10 times of volumes is extracted after 2h in extractor at 100 DEG C, takes extract solution;Repeat to extract three times, merge extract solution;2)Taken out after extract solution is concentrated into 1/5 in concentration tank;Room temperature plus edible alcohol are cooled to 30%, centrifuging and taking supernatant after alcohol precipitation;Again plus edible alcohol is to 70%, taking precipitate is centrifuged after alcohol precipitation;3)Weigh and dissolved by heating after burdock extract 20g, purple potato extract 15g, plus 5 times of water;Weigh 200 ~ 300g of Cordyceps militaris extract(The final content 400mg/L of cordycepin), plus 2 ~ 3 times of water after dissolve by heating;Above-mentioned solution is sufficiently mixed while hot, 50g honey seasonings are added;Add high quality liquor and water to be sufficiently stirred for after cooling, modulate final alcoholic strength to filter canned after 10 degree.
Description
Technical field
The present invention relates to technical field of medicine preparation, more particularly to a kind of system for the Cordyceps militaris magma product for improving immunity
Standby technique.
Background technology
Cordyceps militaris is also known as northern Chinese caterpillar Fungus, Cordceps militaris, pupa grass, and the not old grass of popular name, is modern Valuable Herbal Medicine.Cordyceps militaris belongs to
In Eumycota, Clavicipitaceae.Modern pharmacology research proves, in cordyceps sinensis containing cordycepin, cordycepic acid and various amino acid and
Trace element etc., its pharmacological action is that can improve immunity of organisms and have to nervous system and cardiovascular system etc. preferable
Protective effect.Cordyceps militaris is mainly grown in Changbaishan area in Jilin Province, and its edible and medical value can be with traditional winter worm
Summer grass matches in excellence or beauty.Cordyceps Resources lack, and supply falls short of demand, therefore turn into the focus that educational circles pays close attention to the exploitation of Cordyceps militaris.
Through clinical research, it has antibacterial, antiviral, radioresistance, antitumor, enhancing immunoloregulation function, prevention heart and brain blood
Pipe disease etc. is acted on.Cordyceps militaris is increasingly subject to the concern of people with its magical pharmacological action and liked, it cultivates product
Validity more illustrate its wide development prospect to people, but purification to Cordyceps militaris monomer component and study also not
It is enough abundant.
Cordyceps militaris product on the market has capsule, powder tablet, oral liquid, complexing agent, drinks and fructification etc. now, these
Product can not all give full play to effect of Cordyceps militaris or be unable to reach its preferable effect.Capsule, powder tablet for example on the market
By the absorption of human body itself it is that can not absorb the functional component of Cordyceps militaris well with fructification;And existing oral liquid,
Functional component content in complexing agent and drinks is too low, and preferable effect can not be reached again.
The content of the invention
The technical problems to be solved by the invention are to provide a kind of preparation work for the Cordyceps militaris magma product for improving immunity
Skill, to solve caused above-mentioned multinomial defect in the prior art.
To achieve the above object, the present invention provides following technical scheme:A kind of Cordyceps militaris magma production for improving immunity
The preparation technology of product, comprises the following steps:
1)Organic solvent extractive technique:Cordyceps militaris is crushed to 100 mesh, plus 10 times of volumes 20% edible alcohol in extractor
Extracted at 100 DEG C after 2h, take extract solution;Repeat to extract three times, merge extract solution;
2)Organic solvent stage extraction technology:Taken out after extract solution is concentrated into 1/5 in concentration tank;Be cooled to room temperature add it is edible
Alcohol is to 30%, centrifuging and taking supernatant after alcohol precipitation;Again plus edible alcohol is to 70%, taking precipitate is centrifuged after alcohol precipitation;
3)Weigh and dissolved by heating after burdock extract 20g, purple potato extract 15g, plus 5 times of water;Weigh Cordyceps militaris extract 200 ~
300g(The final content 400mg/L of cordycepin), plus 2 ~ 3 times of water after dissolve by heating;Above-mentioned solution is sufficiently mixed while hot, added
50g honey seasonings;Add high quality liquor and water to be sufficiently stirred for after cooling, modulate final alcoholic strength to filter canned after 10 degree.
Beneficial effect using above technical scheme is:The present invention in order to meet hypoimmunity crowd to cordyceps sinensis function into
That divides absorbs, and developing one kind makes cordycepin dissolution extraction and purifying process as far as possible completely from cordyceps sinensis, and adds same
The burdock extract and purple potato extract that sample has strengthen immunity effect carry out local flavor modulation, form cordycepin magma product,
Human body is set to eat after the cordyceps sinensis magma of this high concentration, the functional component such as cordycepin can be fed rapidly into target organ, effectively
Strengthen the immunity of human body.
Embodiment
With reference to the preferred reality of the preparation technology for the Cordyceps militaris magma product for describing present invention raising immunity in detail
Apply mode.
The present invention improves the embodiment of the preparation technology of the Cordyceps militaris magma product of immunity:One kind improves immune
The preparation technology of the Cordyceps militaris magma product of power, comprises the following steps:
1)Cordyceps militaris is crushed to 100 mesh, plus 20% edible alcohol of 10 times of volumes is extracted after 2h in extractor at 100 DEG C, is taken
Extract solution;Repeat to extract three times, merge extract solution;
2)Taken out after extract solution is concentrated into 1/5 in concentration tank;Room temperature plus edible alcohol are cooled to 30%, is centrifuged after alcohol precipitation
Take supernatant;Again plus edible alcohol is to 70%, taking precipitate is centrifuged after alcohol precipitation;
3)Cordyceps militaris magma preparation technology:Weigh and dissolved by heating after burdock extract 20g, purple potato extract 15g, plus 5 times of water;Claim
Take 200 ~ 300g of Cordyceps militaris extract(The final content 400mg/L of cordycepin), plus 2 ~ 3 times of water after dissolve by heating;By above-mentioned solution
It is sufficiently mixed while hot, adds 50g honey seasonings;High quality liquor and water is added to be sufficiently stirred for after cooling, it is 10 to modulate final alcoholic strength
Filtered after degree canned.
In the preparation technology of the present invention:
1. the concentration 20% that organic solvent is extracted;The concentration 70% of organic solvent segmentation separation, 30%.
2. functional component preparing process:The Cordyceps militaris magma isolated and purified mixes burdock and purple potato extract is carried with strengthening it
Effect of high immunity, and the raising absorption of human body ability by carrier of high quality liquor.
Cordyceps militaris product on the market has capsule, powder tablet, oral liquid, complexing agent, drinks and fructification etc. now, these
Product can not all give full play to effect of Cordyceps militaris or be unable to reach its preferable effect.Capsule, powder tablet for example on the market
By the absorption of human body itself it is that can not absorb the functional component of Cordyceps militaris well with fructification;And existing oral liquid,
Functional component content in complexing agent and drinks is too low, and preferable effect can not be reached again.
Efficiently to utilize cordyceps sinensis, play the function of cordyceps sinensis, it is just necessary:
1. make the cordycepin dissolution from cordyceps sinensis completely as far as possible;
2. high concentration is taken in;
3. it is fed rapidly into target organ.
The present invention meets above-mentioned 3 requirements.
Based on above-mentioned, structure of the present invention improves the preparation technology of the Cordyceps militaris magma product of immunity compared with prior art
Have the beneficial effect that:The present invention absorbs to meet hypoimmunity crowd to cordyceps sinensis functional component, and developing one kind makes
Cordycepin dissolution extraction and purifying process as far as possible completely from cordyceps sinensis, and add the same burdock with strengthen immunity effect
Extract and purple potato extract carry out local flavor modulation, form cordycepin magma product, human body is eaten the cordyceps sinensis of this high concentration
After magma, the functional component such as cordycepin can be fed rapidly into target organ, effectively strengthen the immunity of human body.
Above-described is only the preferred embodiment of the present invention, it is noted that for one of ordinary skill in the art
For, without departing from the concept of the premise of the invention, various modifications and improvements can be made, these belong to the present invention
Protection domain.
Claims (1)
1. a kind of preparation technology for the Cordyceps militaris magma product for improving immunity, it is characterised in that:Comprise the following steps:
1)Cordyceps militaris is crushed to 100 mesh, plus 20% edible alcohol of 10 times of volumes is extracted after 2h in extractor at 100 DEG C, is taken
Extract solution;Repeat to extract three times, merge extract solution;
2)Taken out after extract solution is concentrated into 1/5 in concentration tank;Room temperature plus edible alcohol are cooled to 30%, is centrifuged after alcohol precipitation
Take supernatant;Again plus edible alcohol is to 70%, taking precipitate is centrifuged after alcohol precipitation;
3)Weigh and dissolved by heating after burdock extract 20g, purple potato extract 15g, plus 5 times of water;Weigh Cordyceps militaris extract 200 ~
300g(The final content 400mg/L of cordycepin), plus 2 ~ 3 times of water after dissolve by heating;Above-mentioned solution is sufficiently mixed while hot, added
50g honey seasonings;Add high quality liquor and water to be sufficiently stirred for after cooling, modulate final alcoholic strength to filter canned after 10 degree.
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CN201710323091.6A CN107304398A (en) | 2017-05-09 | 2017-05-09 | A kind of preparation technology for the Cordyceps militaris magma product for improving immunity |
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AU2003271037A1 (en) * | 2003-09-28 | 2005-04-14 | Ailing Li | The extractive of aweto and process for its preparation and uses |
CN101669561A (en) * | 2009-09-23 | 2010-03-17 | 吉林市新科奇保健食品有限公司 | Tea drink with main materials of purple potato leaves and blueberry leaves and preparation method thereof |
CN103087887A (en) * | 2013-01-10 | 2013-05-08 | 阳泉市浩丰小杂粮专业合作社 | Purple sweet potato health care wine and preparation method thereof |
CN105360824A (en) * | 2014-11-14 | 2016-03-02 | 广州王老吉药业股份有限公司 | Chinese caterpillar fungus beverage and preparation method thereof |
CN105801718A (en) * | 2016-04-21 | 2016-07-27 | 浙江工业大学 | Extraction method of cordyceps flower polysaccharide |
CN106148136A (en) * | 2016-09-23 | 2016-11-23 | 安徽智联管理咨询有限公司 | A kind of brewing method of Agaricus blazei Murrill health promoting wine |
CN106281919A (en) * | 2016-08-22 | 2017-01-04 | 广州加维舒医药有限公司 | A kind of Cordyceps militaris (L.) Link. modulation wine and preparation method thereof |
CN106490260A (en) * | 2016-10-19 | 2017-03-15 | 安徽省新旭堂茶业有限公司 | A kind of Radix Glycyrrhizae scented tea of enhance immunity |
-
2017
- 2017-05-09 CN CN201710323091.6A patent/CN107304398A/en active Pending
Patent Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
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AU2003271037A1 (en) * | 2003-09-28 | 2005-04-14 | Ailing Li | The extractive of aweto and process for its preparation and uses |
CN101669561A (en) * | 2009-09-23 | 2010-03-17 | 吉林市新科奇保健食品有限公司 | Tea drink with main materials of purple potato leaves and blueberry leaves and preparation method thereof |
CN103087887A (en) * | 2013-01-10 | 2013-05-08 | 阳泉市浩丰小杂粮专业合作社 | Purple sweet potato health care wine and preparation method thereof |
CN105360824A (en) * | 2014-11-14 | 2016-03-02 | 广州王老吉药业股份有限公司 | Chinese caterpillar fungus beverage and preparation method thereof |
CN105801718A (en) * | 2016-04-21 | 2016-07-27 | 浙江工业大学 | Extraction method of cordyceps flower polysaccharide |
CN106281919A (en) * | 2016-08-22 | 2017-01-04 | 广州加维舒医药有限公司 | A kind of Cordyceps militaris (L.) Link. modulation wine and preparation method thereof |
CN106148136A (en) * | 2016-09-23 | 2016-11-23 | 安徽智联管理咨询有限公司 | A kind of brewing method of Agaricus blazei Murrill health promoting wine |
CN106490260A (en) * | 2016-10-19 | 2017-03-15 | 安徽省新旭堂茶业有限公司 | A kind of Radix Glycyrrhizae scented tea of enhance immunity |
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