CN107290534A - 一种血液细胞捕获芯片及方法 - Google Patents
一种血液细胞捕获芯片及方法 Download PDFInfo
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- CN107290534A CN107290534A CN201710566146.6A CN201710566146A CN107290534A CN 107290534 A CN107290534 A CN 107290534A CN 201710566146 A CN201710566146 A CN 201710566146A CN 107290534 A CN107290534 A CN 107290534A
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- 239000000427 antigen Substances 0.000 claims abstract description 27
- 102000036639 antigens Human genes 0.000 claims abstract description 27
- 108091007433 antigens Proteins 0.000 claims abstract description 27
- 239000008280 blood Substances 0.000 claims abstract description 20
- 210000004369 blood Anatomy 0.000 claims abstract description 19
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- 238000004220 aggregation Methods 0.000 claims abstract description 6
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- 208000005443 Circulating Neoplastic Cells Diseases 0.000 abstract description 8
- 238000001514 detection method Methods 0.000 abstract description 6
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Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56966—Animal cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
- G01N33/533—Production of labelled immunochemicals with fluorescent label
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Microbiology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Zoology (AREA)
- Virology (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Abstract
Description
Claims (10)
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201710566146.6A CN107290534A (zh) | 2017-07-12 | 2017-07-12 | 一种血液细胞捕获芯片及方法 |
PCT/CN2017/100740 WO2019010787A1 (zh) | 2017-07-12 | 2017-09-06 | 一种血液细胞捕获芯片及方法 |
Applications Claiming Priority (1)
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CN201710566146.6A CN107290534A (zh) | 2017-07-12 | 2017-07-12 | 一种血液细胞捕获芯片及方法 |
Publications (1)
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CN107290534A true CN107290534A (zh) | 2017-10-24 |
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CN201710566146.6A Pending CN107290534A (zh) | 2017-07-12 | 2017-07-12 | 一种血液细胞捕获芯片及方法 |
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CN (1) | CN107290534A (zh) |
WO (1) | WO2019010787A1 (zh) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108949497A (zh) * | 2018-04-28 | 2018-12-07 | 天津大学 | 极微量循环肿瘤细胞的特异性单细胞定点捕捉芯片 |
CN109985583A (zh) * | 2019-03-12 | 2019-07-09 | 清华大学深圳研究生院 | 一种磁性荧光编码微球的制备方法及其应用 |
CN112710833A (zh) * | 2021-01-13 | 2021-04-27 | 上海交通大学 | 基于微管流控芯片的细胞捕获方法 |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TWI719605B (zh) | 2019-08-23 | 2021-02-21 | 國立清華大學 | 捕獲循環腫瘤癌細胞裝置、其方法以及循環腫瘤癌細胞捕獲暨藥物敏感性測試的方法 |
CN111944656B (zh) * | 2020-07-06 | 2022-07-29 | 东南大学 | 一种微流控细胞磁捕获与检测系统及其捕获与检测方法 |
CN114471752A (zh) * | 2020-10-27 | 2022-05-13 | 京东方科技集团股份有限公司 | 一种芯片及其制备方法 |
CN114295688B (zh) * | 2021-12-30 | 2023-05-23 | 北京航空航天大学 | 一种适用于微通道异质物检测的电阻抗层析成像传感器 |
Citations (7)
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WO1998016101A1 (en) * | 1996-10-15 | 1998-04-23 | Bio-Tech Imaging, Inc. | Reagent system and kit for detecting hiv infected cells |
CN101936992A (zh) * | 2010-09-17 | 2011-01-05 | 湖南大学 | 快速检测大肠杆菌的方法及所用到的微流控芯片及其制备工艺 |
CN103339249A (zh) * | 2011-01-13 | 2013-10-02 | 索尼公司 | 细胞核观察基板和细胞核观察装置 |
CN103878039A (zh) * | 2014-03-25 | 2014-06-25 | 国家纳米科学中心 | 一种微流控芯片、使用其合成功能纳米颗粒的方法及应用 |
CN104471380A (zh) * | 2012-07-06 | 2015-03-25 | 株式会社日立高新技术 | 分析装置以及分析方法 |
CN104892815A (zh) * | 2015-05-06 | 2015-09-09 | 吉林大学 | 表面带正电荷具有聚集诱导荧光增强性质的荧光纳米微球及其生物应用 |
CN206930674U (zh) * | 2017-07-12 | 2018-01-26 | 华讯方舟科技有限公司 | 一种血液细胞捕获芯片 |
Family Cites Families (1)
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CN106147755B (zh) * | 2016-06-24 | 2018-10-09 | 华南理工大学 | 抗体修饰的荧光纳米粒子及在癌细胞靶向成像中的应用 |
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2017
- 2017-07-12 CN CN201710566146.6A patent/CN107290534A/zh active Pending
- 2017-09-06 WO PCT/CN2017/100740 patent/WO2019010787A1/zh active Application Filing
Patent Citations (7)
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WO1998016101A1 (en) * | 1996-10-15 | 1998-04-23 | Bio-Tech Imaging, Inc. | Reagent system and kit for detecting hiv infected cells |
CN101936992A (zh) * | 2010-09-17 | 2011-01-05 | 湖南大学 | 快速检测大肠杆菌的方法及所用到的微流控芯片及其制备工艺 |
CN103339249A (zh) * | 2011-01-13 | 2013-10-02 | 索尼公司 | 细胞核观察基板和细胞核观察装置 |
CN104471380A (zh) * | 2012-07-06 | 2015-03-25 | 株式会社日立高新技术 | 分析装置以及分析方法 |
CN103878039A (zh) * | 2014-03-25 | 2014-06-25 | 国家纳米科学中心 | 一种微流控芯片、使用其合成功能纳米颗粒的方法及应用 |
CN104892815A (zh) * | 2015-05-06 | 2015-09-09 | 吉林大学 | 表面带正电荷具有聚集诱导荧光增强性质的荧光纳米微球及其生物应用 |
CN206930674U (zh) * | 2017-07-12 | 2018-01-26 | 华讯方舟科技有限公司 | 一种血液细胞捕获芯片 |
Non-Patent Citations (2)
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MENG GAO等: "Targeted imaging of EGFR overexpressed cancer cells by brightly fluorescent nanoparticles conjugated with cetuximab", 《NANOSCALE》, pages 1 - 6 * |
王子龙: "聚集诱导发光分子的合成及其在荧光纳米粒子生物成像中的应用", 《中国优秀硕士学位论文全文数据库(工程科技Ⅰ辑)》, vol. 2013, no. 08, pages 020 - 96 * |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108949497A (zh) * | 2018-04-28 | 2018-12-07 | 天津大学 | 极微量循环肿瘤细胞的特异性单细胞定点捕捉芯片 |
CN108949497B (zh) * | 2018-04-28 | 2021-11-02 | 天津大学 | 极微量循环肿瘤细胞的特异性单细胞定点捕捉芯片 |
CN109985583A (zh) * | 2019-03-12 | 2019-07-09 | 清华大学深圳研究生院 | 一种磁性荧光编码微球的制备方法及其应用 |
CN112710833A (zh) * | 2021-01-13 | 2021-04-27 | 上海交通大学 | 基于微管流控芯片的细胞捕获方法 |
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