CN107281264A - A kind of preparation method and Cortex cinnamomi japonici (Ramulus Cinnamomi) extract that Cortex cinnamomi japonici (Ramulus Cinnamomi) extract is produced from cinnamomi cortex pulveratus residue - Google Patents
A kind of preparation method and Cortex cinnamomi japonici (Ramulus Cinnamomi) extract that Cortex cinnamomi japonici (Ramulus Cinnamomi) extract is produced from cinnamomi cortex pulveratus residue Download PDFInfo
- Publication number
- CN107281264A CN107281264A CN201710572472.8A CN201710572472A CN107281264A CN 107281264 A CN107281264 A CN 107281264A CN 201710572472 A CN201710572472 A CN 201710572472A CN 107281264 A CN107281264 A CN 107281264A
- Authority
- CN
- China
- Prior art keywords
- cinnamomi
- extract
- cortex
- ethanol
- japonici
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000284 extract Substances 0.000 title claims abstract description 94
- 239000008989 cinnamomi cortex Substances 0.000 title claims abstract description 38
- 238000002360 preparation method Methods 0.000 title claims abstract description 23
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 71
- 244000037364 Cinnamomum aromaticum Species 0.000 claims abstract description 32
- 235000014489 Cinnamomum aromaticum Nutrition 0.000 claims abstract description 32
- 239000000843 powder Substances 0.000 claims abstract description 30
- 239000007788 liquid Substances 0.000 claims abstract description 24
- 238000000605 extraction Methods 0.000 claims abstract description 18
- 238000001914 filtration Methods 0.000 claims abstract description 13
- 239000000469 ethanolic extract Substances 0.000 claims abstract description 11
- 238000010992 reflux Methods 0.000 claims abstract description 10
- 238000010438 heat treatment Methods 0.000 claims abstract description 7
- 239000000203 mixture Substances 0.000 claims abstract description 7
- 239000012141 concentrate Substances 0.000 claims abstract description 6
- 238000002481 ethanol extraction Methods 0.000 claims abstract description 5
- 229930003944 flavone Natural products 0.000 claims abstract description 4
- 150000002213 flavones Chemical class 0.000 claims abstract description 4
- 235000011949 flavones Nutrition 0.000 claims abstract description 4
- 235000013824 polyphenols Nutrition 0.000 claims abstract description 4
- 238000000926 separation method Methods 0.000 claims abstract description 4
- 238000004806 packaging method and process Methods 0.000 claims description 7
- 238000001694 spray drying Methods 0.000 claims description 5
- 238000010348 incorporation Methods 0.000 claims description 3
- -1 polyphenol Compound Chemical class 0.000 claims 1
- 238000000034 method Methods 0.000 abstract description 11
- 230000008901 benefit Effects 0.000 abstract description 5
- 241000196324 Embryophyta Species 0.000 abstract description 4
- 150000008442 polyphenolic compounds Chemical class 0.000 abstract description 3
- 238000007796 conventional method Methods 0.000 abstract description 2
- 239000000463 material Substances 0.000 abstract description 2
- 238000002156 mixing Methods 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- 235000019082 Osmanthus Nutrition 0.000 description 4
- 241000333181 Osmanthus Species 0.000 description 4
- 238000005507 spraying Methods 0.000 description 3
- 241000522254 Cassia Species 0.000 description 2
- 241000723347 Cinnamomum Species 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 229930003935 flavonoid Natural products 0.000 description 2
- 150000002215 flavonoids Chemical class 0.000 description 2
- 235000017173 flavonoids Nutrition 0.000 description 2
- 239000002994 raw material Substances 0.000 description 2
- 238000011084 recovery Methods 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 244000080208 Canella winterana Species 0.000 description 1
- 235000008499 Canella winterana Nutrition 0.000 description 1
- 244000281594 Cassia siamea Species 0.000 description 1
- 241000252804 Cinnamomum insularimontanum Species 0.000 description 1
- 235000002428 Cinnamomum japonicum Nutrition 0.000 description 1
- 241000107513 Cinnamomum subavenium Species 0.000 description 1
- 235000013409 condiments Nutrition 0.000 description 1
- 238000010411 cooking Methods 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 235000011194 food seasoning agent Nutrition 0.000 description 1
- 150000002576 ketones Chemical class 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 235000012054 meals Nutrition 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 235000013599 spices Nutrition 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
- A23L27/10—Natural spices, flavouring agents or condiments; Extracts thereof
- A23L27/11—Natural spices, flavouring agents or condiments; Extracts thereof obtained by solvent extraction
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/37—Extraction at elevated pressure or temperature, e.g. pressurized solvent extraction [PSE], supercritical carbon dioxide extraction or subcritical water extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Botany (AREA)
- Mycology (AREA)
- Food Science & Technology (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Nutrition Science (AREA)
- Medical Informatics (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Polymers & Plastics (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Plant Substances (AREA)
- Cosmetics (AREA)
Abstract
The invention belongs to technical field of plant extraction, more particularly to a kind of preparation method that Cortex cinnamomi japonici (Ramulus Cinnamomi) extract is produced from cinnamomi cortex pulveratus residue, comprise the following steps：(1) Feedstock treating：By in the cinnamomi cortex pulveratus residue input extractor after SCF-CO 2 cassia oil；(2) ethanol is extracted：With 30 70% ethanol to cinnamomi cortex pulveratus residue heating and refluxing extraction twice, merging extract decoction twice, obtain ethanol extract；(3) separation of solid and liquid：It is separated by filtration ethanol extract and ethanol extraction clear liquid is made；(4) concentrate：Ethanol is extracted into clear liquid after ethanol is recovered under reduced pressure, thick medicinal extract is concentrated to give；Extract powder is made after spray-dried, crushing, mixing.In addition, the present invention also provides a kind of extract, it is made up of above-mentioned preparation method, Cortex cinnamomi japonici (Ramulus Cinnamomi) extract is the mixture of cassia bark flavones and polyphenol.The cassia bark extraction process of the present invention, not only makes good use of cassia bark than conventional method and extracts Cortex cinnamomi japonici (Ramulus Cinnamomi) extract saving cost of material, and yield is higher than Traditional Method, and economic benefit is more prominent.
Description
【Technical field】
The invention belongs to technical field of plant extraction, more particularly to a kind of system that Cortex cinnamomi japonici (Ramulus Cinnamomi) extract is produced from cinnamomi cortex pulveratus residue
Preparation Method and Cortex cinnamomi japonici (Ramulus Cinnamomi) extract.
【Background technology】
Cassia bark is also known as Chinese cassia tree, official osmanthus or fragrant osmanthus, is the tree such as canella cinnamomum japonicum, burmannii, cinnamomum chingii Metcalf, Chinese cassia tree or river osmanthus
The common name of skin.This product is conventional Chinese medicine, is food flavor or condiment for cooking again.The former plant of commodity cassia bark is more complicated, there are about
More than ten plant, and are Lauraceae cinnamon.What various regions were commonly used has 8 kinds, wherein mainly having cassia tree, cinnamomum obtusifoliumNees, burmannii and south China osmanthus etc.
Other species are generally regional medication.Each kind is used as spices in Ancient Western.Fricassee seasoning is given with it in Chinese meal, is five-spice powder
One of composition.
At present, cassia bark is mainly used in extracting cassia oil, but most of cinnamomi cortex pulveratus dregs of a decoction after supercritical extract cassia oil
Do not reprocessed, the also active component containing many cassia bark ketone of the cassia bark dregs of a decoction after extraction is not comprehensively utilized, utilization rate
Low, comprehensive utilization cassia bark can improve the economic benefit of society, can more save resource.
In view of above-mentioned technical problem, a kind of system that Cortex cinnamomi japonici (Ramulus Cinnamomi) extract is produced from cinnamomi cortex pulveratus residue of the applicant's exploitation
Preparation Method.
【The content of the invention】
The present invention for the cinnamomi cortex pulveratus utilization rate after overcoming the existing cassia oil through supercritical extract it is low the problem of there is provided one kind
The preparation method of Cortex cinnamomi japonici (Ramulus Cinnamomi) extract is produced from cinnamomi cortex pulveratus residue, the method not only makes good use of cassia bark than conventional method and extracts cassia bark extraction
Thing saves cost of material, and yield is higher than Traditional Method, and economic benefit is more prominent.
The present invention is the technical scheme that is used of its technical problem of solution：
A kind of preparation method that Cortex cinnamomi japonici (Ramulus Cinnamomi) extract is produced from cinnamomi cortex pulveratus residue, comprises the following steps：
(1) Feedstock treating：By in the cinnamomi cortex pulveratus residue input extractor after SCF-CO 2 cassia oil；
(2) ethanol is extracted：With 30-70% ethanol to the cinnamomi cortex pulveratus residue heating and refluxing extraction in step (1) twice, merge
Decoction is extracted twice, obtains ethanol extract；
(3) solid- liquid separation：The ethanol extract in step (2) is separated by filtration, ethanol is obtained and extracts clear liquid；
(4) concentrate：Ethanol in step (3) is extracted into clear liquid after ethanol is recovered under reduced pressure, thick medicinal extract is concentrated to give；
(5) it is spray-dried：By the thick medicinal extract in step (4) by being spray-dried to obtain extract powder；
(6) crush：Extract powder in step (5) is crushed by Universalpulverizer, 80 eye mesh screens are crossed；
(7) mix：The extract powder that 80 eye mesh screens are crossed in step (6) is placed in mixer and mixed, must be mixed
Extract powder；
Preferably, the cinnamomi cortex pulveratus described in step (1) after SCF-CO 2 cassia oil was the sieve powder of 10-60 mesh.
Preferably, 30-70% ethanol heating and refluxing extraction is measured twice with 5-10 times when ethanol is extracted in step (2), every time
2-4 hours, Extracting temperature was at 45-80 DEG C.
Preferably, with sock filtration of the pump by 30 mesh when being separated by filtration ethanol extract in step (3), ethanol extraction is obtained
Clear liquid.
Preferably, ethanol extraction clear liquid is concentrated under reduced pressure under vacuum 0.06-0.09MPa in step (4), is concentrated into ratio
Weight is the thick paste of 15-30 Baume degrees.
Preferably, the EAT of spray drying is 170-190 DEG C in step (5), and leaving air temp is 70-80 DEG C.
Preferably, in step (7) by cross 80 eye mesh screens extract powder be placed in mixed in mixer when, incorporation time is
10-60 minutes.
Preferably, a packaging step is also included after step (7)：The extract powder mixed is subjected to bag film bag
Dress.
A kind of Cortex cinnamomi japonici (Ramulus Cinnamomi) extract, the Cortex cinnamomi japonici (Ramulus Cinnamomi) extract is extracted by one kind described above from cinnamomi cortex pulveratus residue production cassia bark
The preparation method of thing is made, and described Cortex cinnamomi japonici (Ramulus Cinnamomi) extract is cassia bark flavones and the mixture of polyphenol.
Compared with prior art, Cortex cinnamomi japonici (Ramulus Cinnamomi) extract extraction process of the invention has the following advantages：
1st, present invention process is alcohol extracting taking technique, fully can be extracted cassia bark Flavonoid substances, plays it and integrates treatment
Effect；
2nd, the present invention takes the raw material powder after extraction cassia oil to be extracted, and recovery rate is high, saves resource, reduces cost,
The purposes of cassia bark is comprehensively utilized；
3rd, present invention process is simple, and product yield is high, takes spray drying, and its product colour keeps preferable.
Below in conjunction with embodiment, the invention will be further described.
【Brief description of the drawings】
Technical scheme in order to illustrate the embodiments of the present invention more clearly, makes required in being described below to embodiment
Accompanying drawing is briefly described, it should be apparent that, drawings in the following description are only some embodiments of the present invention, for
For those of ordinary skill in the art, on the premise of not paying creative work, other can also be obtained according to these accompanying drawings
Accompanying drawing.
Fig. 1 is the process chart of the present invention.
【Embodiment】
For the ease of understanding the present invention, it is as follows that the present invention enumerates embodiment.Those skilled in the art are it will be clearly understood that the reality
Apply example to be only to aid in understanding the present invention, be not construed as the concrete restriction to the present invention.
A kind of preparation method that Cortex cinnamomi japonici (Ramulus Cinnamomi) extract is produced from cinnamomi cortex pulveratus residue, comprises the following steps：
(1) Feedstock treating：By in the cinnamomi cortex pulveratus residue input extractor after SCF-CO 2 cassia oil.
Cinnamomi cortex pulveratus after the cassia oil through SCF-CO 2 was the sieve powder of 10-60 mesh.
(2) ethanol is extracted：With 30-70% ethanol to the cinnamomi cortex pulveratus residue heating and refluxing extraction in step (1) twice, merge
Decoction is extracted twice, obtains ethanol extract.
Ethanol measures 10-80% ethanol heating and refluxing extraction twice when extracting with 5-10 times, each 2-4 hours, Extracting temperature
At 45-80 DEG C.
(3) solid- liquid separation：The ethanol extract in step (2) is separated by filtration, ethanol is obtained and extracts clear liquid.
With sock filtration of the pump by 30 mesh when being separated by filtration ethanol extract, obtain ethanol and extract clear liquid.
(4) concentrate：Ethanol in step (3) is extracted into clear liquid after ethanol is recovered under reduced pressure, thick medicinal extract is concentrated to give.
Ethanol extraction clear liquid is concentrated under reduced pressure under vacuum 0.06-0.09MPa, proportion is concentrated into for 15-30 Baume degrees
Thick paste.
(5) it is spray-dried：By the thick medicinal extract in step (4) by being spray-dried to obtain extract powder.
The EAT of spray drying is 170-190 DEG C, and leaving air temp is 70-80 DEG C.
(6) crush：Extract powder in step (5) is crushed by Universalpulverizer, 80 eye mesh screens are crossed.
(7) mix：The extract powder that 80 eye mesh screens are crossed in step (6) is placed in mixer and mixed, incorporation time is
10-60 minutes, the extract powder that must be mixed.
(8) pack：The extract powder mixed in step (7) is subjected to bag film packaging.
Embodiment 1
This specific embodiment produces the preparation method of Cortex cinnamomi japonici (Ramulus Cinnamomi) extract from cinnamomi cortex pulveratus residue：Take 10 kilograms of cinnamomi cortex pulveratus, plus 5 times
Measure 70% alcohol reflux and extract 2 times, 2 hours every time, 45 DEG C of Extracting temperature, extract solution, which crosses 30 mesh sock filtrations through pump and obtains ethanol, to be carried
Take clear liquid, extract clear liquid and be recovered under reduced pressure at 65 DEG C of temperature, vacuum 0.06MPa after ethanol, concentrate, be concentrated into proportion for 15 mother-in-law
The thick medicinal extract of U.S. degree (50 DEG C of surveys)；Thick medicinal extract is spray-dried, spraying EAT is 170 DEG C, leaving air temp is 70 DEG C,
Obtain 1.0 kilograms of extract powder；Extract powder is crushed, 80 mesh sieves are crossed, is mixed, packaging is produced, and Cortex cinnamomi japonici (Ramulus Cinnamomi) extract is received
Rate is 12.0%, color raciness.
Embodiment 2
This specific embodiment produces the preparation method of Cortex cinnamomi japonici (Ramulus Cinnamomi) extract from cinnamomi cortex pulveratus residue：Take 10 kilograms of cinnamomi cortex pulveratus, plus 8 times
Measure 50% alcohol reflux and extract 2 times, 3 hours every time, 65 DEG C of Extracting temperature, extract solution, which crosses 30 mesh sock filtrations through pump and obtains ethanol, to be carried
Take clear liquid, extract clear liquid and be recovered under reduced pressure at 65 DEG C of temperature, vacuum 0.08MPa after ethanol, concentrate, be concentrated into proportion for 20 mother-in-law
The thick medicinal extract of U.S. degree (50 DEG C of surveys)；Thick medicinal extract is spray-dried, spraying EAT is 180 DEG C, leaving air temp is 75 DEG C,
Obtain 1.5 kilograms of extract powder；Extract powder is crushed, 80 mesh sieves are crossed, is mixed, packaging is produced, and Cortex cinnamomi japonici (Ramulus Cinnamomi) extract is received
Rate is 15.0%, color raciness.
Embodiment 3
This specific embodiment produces the preparation method of Cortex cinnamomi japonici (Ramulus Cinnamomi) extract from cinnamomi cortex pulveratus residue：10 kilograms of cinnamomi cortex pulveratus is taken, plus 10
30% alcohol reflux of amount is extracted 2 times again, and 4 hours every time, 80 DEG C of Extracting temperature, extract solution crossed 30 mesh sock filtrations through pump and obtains ethanol
Clear liquid is extracted, clear liquid is extracted and is recovered under reduced pressure at 65 DEG C of temperature, vacuum 0.09MPa after ethanol, concentrated, it is 30 to be concentrated into proportion
The thick medicinal extract of mother-in-law U.S. degree (50 DEG C of surveys)；Thick medicinal extract is spray-dried, spraying EAT is 190 DEG C, and leaving air temp is 80
DEG C, obtain 1.6 kilograms of extract powder；Extract powder is crushed, 80 mesh sieves are crossed, is mixed, packaging is produced, and cassia bark is extracted
Thing yield is 20.0%, color raciness.
It refer to table 1, traditional extraction technique and the contrast experiment of extraction process of the embodiment of the present invention
A kind of Cortex cinnamomi japonici (Ramulus Cinnamomi) extract, the Cortex cinnamomi japonici (Ramulus Cinnamomi) extract a kind of from cinnamomi cortex pulveratus residue produces Cortex cinnamomi japonici (Ramulus Cinnamomi) extract by above-mentioned
Preparation method is made, and Cortex cinnamomi japonici (Ramulus Cinnamomi) extract is the mixture of cassia bark flavones and polyphenol.The Cortex cinnamomi japonici (Ramulus Cinnamomi) extract technological advantage of the present invention：1、
Present invention process is alcohol extracting taking technique, fully can extract cassia bark Flavonoid substances, play its comprehensive therapeutic effect；2nd, it is of the invention
The raw material powder after extraction cassia oil is taken to be extracted, recovery rate is high, saving resource reduces cost, the purposes of cassia bark is able to comprehensive
Close and utilize；3rd, present invention process is simple, and product yield is high, takes spray drying, and its product colour keeps preferable.
The foregoing is only presently preferred embodiments of the present invention, not for limiting the scope implemented of the present invention, other it is all its
Principle and basic structure are identical or approximate with the present invention, within protection scope of the present invention.
Claims (9)
1. a kind of preparation method that Cortex cinnamomi japonici (Ramulus Cinnamomi) extract is produced from cinnamomi cortex pulveratus residue, it is characterised in that comprise the following steps：
(1) Feedstock treating：By in the cinnamomi cortex pulveratus residue input extractor after SCF-CO 2 cassia oil；
(2) ethanol is extracted：With 30-70% ethanol to the cinnamomi cortex pulveratus residue heating and refluxing extraction in step (1) twice, merge twice
Decoction is extracted, ethanol extract is obtained；
(3) solid- liquid separation：The ethanol extract in step (2) is separated by filtration, ethanol is obtained and extracts clear liquid；
(4) concentrate：Ethanol in step (3) is extracted into clear liquid after ethanol is recovered under reduced pressure, thick medicinal extract is concentrated to give；
(5) it is spray-dried：By the thick medicinal extract in step (4) by being spray-dried to obtain extract powder；
(6) crush：Extract powder in step (5) is crushed by Universalpulverizer, 80 eye mesh screens are crossed；
(7) mix：The extract powder that 80 eye mesh screens are crossed in step (6) is placed in mixer and mixed, the extraction that must be mixed
Thing powder.
2. a kind of preparation method that Cortex cinnamomi japonici (Ramulus Cinnamomi) extract is produced from cinnamomi cortex pulveratus residue according to claim 1, it is characterised in that：
Cinnamomi cortex pulveratus described in step (1) after SCF-CO 2 cassia oil was the sieve powder of 10-60 mesh.
3. a kind of preparation method that Cortex cinnamomi japonici (Ramulus Cinnamomi) extract is produced from cinnamomi cortex pulveratus residue according to claim 1, it is characterised in that：
30-70% ethanol heating and refluxing extraction is measured with 5-10 times twice, each 2-4 hours, Extracting temperature when ethanol is extracted in step (2)
At 45-80 DEG C.
4. a kind of preparation method that Cortex cinnamomi japonici (Ramulus Cinnamomi) extract is produced from cinnamomi cortex pulveratus residue according to claim 1, it is characterised in that：
With sock filtration of the pump by 30 mesh when being separated by filtration ethanol extract in step (3), obtain ethanol and extract clear liquid.
5. a kind of preparation method that Cortex cinnamomi japonici (Ramulus Cinnamomi) extract is produced from cinnamomi cortex pulveratus residue according to claim 1, it is characterised in that：
Ethanol extraction clear liquid is concentrated under reduced pressure under vacuum 0.06-0.09MPa in step (4), proportion is concentrated into for 15-30 Baume degrees
Thick paste.
6. a kind of preparation method that Cortex cinnamomi japonici (Ramulus Cinnamomi) extract is produced from cinnamomi cortex pulveratus residue according to claim 1, it is characterised in that：
The EAT of spray drying is 170-190 DEG C in step (5), and leaving air temp is 70-80 DEG C.
7. a kind of preparation method that Cortex cinnamomi japonici (Ramulus Cinnamomi) extract is produced from cinnamomi cortex pulveratus residue according to claim 1, it is characterised in that：
In step (7) by cross 80 eye mesh screens extract powder be placed in mixed in mixer when, incorporation time be 10-60 minutes.
8. a kind of preparation method that Cortex cinnamomi japonici (Ramulus Cinnamomi) extract is produced from cinnamomi cortex pulveratus residue according to claim 1, it is characterised in that：
Also include a packaging step after step (7)：The extract powder mixed is subjected to bag film packaging.
9. a kind of Cortex cinnamomi japonici (Ramulus Cinnamomi) extract, it is characterised in that：The Cortex cinnamomi japonici (Ramulus Cinnamomi) extract is as one kind described in any one of claim 1 to 7
The preparation method for producing Cortex cinnamomi japonici (Ramulus Cinnamomi) extract from cinnamomi cortex pulveratus residue is made, and described Cortex cinnamomi japonici (Ramulus Cinnamomi) extract is mixed for cassia bark flavones and polyphenol
Compound.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710572472.8A CN107281264A (en) | 2017-07-14 | 2017-07-14 | A kind of preparation method and Cortex cinnamomi japonici (Ramulus Cinnamomi) extract that Cortex cinnamomi japonici (Ramulus Cinnamomi) extract is produced from cinnamomi cortex pulveratus residue |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710572472.8A CN107281264A (en) | 2017-07-14 | 2017-07-14 | A kind of preparation method and Cortex cinnamomi japonici (Ramulus Cinnamomi) extract that Cortex cinnamomi japonici (Ramulus Cinnamomi) extract is produced from cinnamomi cortex pulveratus residue |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107281264A true CN107281264A (en) | 2017-10-24 |
Family
ID=60101361
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710572472.8A Pending CN107281264A (en) | 2017-07-14 | 2017-07-14 | A kind of preparation method and Cortex cinnamomi japonici (Ramulus Cinnamomi) extract that Cortex cinnamomi japonici (Ramulus Cinnamomi) extract is produced from cinnamomi cortex pulveratus residue |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107281264A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108576755A (en) * | 2018-04-03 | 2018-09-28 | 广东铭康香精香料有限公司 | A kind of preparation method of betel nut smoked flavor natural perfume material |
| CN109646407A (en) * | 2018-12-17 | 2019-04-19 | 江西赣隆药业有限公司 | For the preparation method of calm, cooling, decompression Cortex Cinnamomi granule and by the granule of this method preparation |
| CN113616690A (en) * | 2021-07-28 | 2021-11-09 | 华南理工大学 | Cinnamon leaf residue extract and preparation method and application thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101460066A (en) * | 2006-03-23 | 2009-06-17 | 草药科学新加坡私人有限公司 | Extracts and methods comprising cinnamon species |
-
2017
- 2017-07-14 CN CN201710572472.8A patent/CN107281264A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101460066A (en) * | 2006-03-23 | 2009-06-17 | 草药科学新加坡私人有限公司 | Extracts and methods comprising cinnamon species |
Non-Patent Citations (1)
| Title |
|---|
| 库咏峰: "《肉桂总黄酮提取分离分析及抗氧化活性研究》", 《中国优秀硕士学位论文全文数据库工程科技辑》 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108576755A (en) * | 2018-04-03 | 2018-09-28 | 广东铭康香精香料有限公司 | A kind of preparation method of betel nut smoked flavor natural perfume material |
| CN109646407A (en) * | 2018-12-17 | 2019-04-19 | 江西赣隆药业有限公司 | For the preparation method of calm, cooling, decompression Cortex Cinnamomi granule and by the granule of this method preparation |
| CN113616690A (en) * | 2021-07-28 | 2021-11-09 | 华南理工大学 | Cinnamon leaf residue extract and preparation method and application thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN110507754A (en) | A kind of semen ziziphi spinosae sleeping tea and preparation method thereof | |
| CN107746749A (en) | A kind of preparation method and Lignum Aquilariae Resinatum extract from agalloch eaglewood residue production Lignum Aquilariae Resinatum extract | |
| CN103393599A (en) | Preparation method of traditional Chinese medicine fine powder | |
| CN105168285B (en) | A kind of ginsenoside extracting solution and its extracting method | |
| CN107281264A (en) | A kind of preparation method and Cortex cinnamomi japonici (Ramulus Cinnamomi) extract that Cortex cinnamomi japonici (Ramulus Cinnamomi) extract is produced from cinnamomi cortex pulveratus residue | |
| CN106085750A (en) | A kind of processing method of Rhizoma Bistortae Radix ziziphi mauritianae health promoting wine | |
| CN108057039A (en) | A kind of Dendrobium officinale polysaccharide and Siberian solomonseal rhizome polysaccharide composition and preparation method and application | |
| CN103211219A (en) | Health food for relieving physical fatigue and preparation method thereof | |
| CN102329715A (en) | Compound Rhodiola rosea wine and preparation method thereof | |
| CN100400064C (en) | Glucoside compound preparation and its preparing process | |
| CN106721839A (en) | A kind of preparation method of the brown sugar ginger electuary for being convenient for carrying and eating | |
| CN109170885A (en) | A method of extracting ginseng effective component | |
| CN102824480B (en) | Auxiliary blood sugar decreasing composite containing tibetan medicine edgeworthia gardneri and preparation method of composite | |
| CN105055707A (en) | Lipid-lowering Chinese herbal medicinal health oral liquid containing shark cartilage powder and preparation method of oral liquid | |
| CN107279647A (en) | The formula and preparation method of two kinds of wilsonii solid beverages | |
| CN103655791A (en) | Lotus leaf-based preparation for treating phlegm and blood stasis simultaneously and application thereof | |
| CN103652155A (en) | Instant molecular health-care tea | |
| CN108126052A (en) | A kind of preparation process for nourishing refreshing particle | |
| CN104223304B (en) | A kind of spirit can the product that menopause symptom be improved and preparation method thereof of releiving | |
| CN1288168C (en) | Polysaccharides compound preparation and method for preparing the same | |
| CN104938990A (en) | Arrowroot nutritional flour convenient to eat and production process thereof | |
| CN105219602B (en) | A kind of hypoglycemic root of kudzu vine yellow rice wine and preparation method thereof | |
| CN104187583A (en) | Processing method for ganoderma lucidum powder | |
| CN104127603A (en) | Preparation process of lipid-lowering tablet | |
| CN106867826A (en) | A kind of seabuckthorn wine and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20171024 |
|
| RJ01 | Rejection of invention patent application after publication |