CN107280006A - It is a kind of that there is hypoglycemic, blood fat reducing function composition, beverage and its application - Google Patents
It is a kind of that there is hypoglycemic, blood fat reducing function composition, beverage and its application Download PDFInfo
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- CN107280006A CN107280006A CN201710522657.8A CN201710522657A CN107280006A CN 107280006 A CN107280006 A CN 107280006A CN 201710522657 A CN201710522657 A CN 201710522657A CN 107280006 A CN107280006 A CN 107280006A
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
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Abstract
The present invention provides a kind of with hypoglycemic, blood fat reducing function composition, beverage and its application, belongs to health food deep process technology field.The composition includes the function raw material of following weight percentage component：Blue or green money willow extract 5~50%, Rhizoma Polygonati Odorati extract 10~30%, wrinkled papaya extract 10~40%, Rhizoma Polygonati extract 10~30%, kudzu root extract 10~30% and polysaccharide prebiotics 0.1%~15%.Blue or green money willow, polysaccharide prebiotics belong to new resource for food in the function raw material that the present invention is provided, radix polygonati officinalis, wrinkled papaya, sealwort, the root of kudzu vine belong to medicine-food two-purpose food materials, equal safety non-toxic, with obvious hypoglycemic, blood fat reducing function, is especially suitable for high blood glucose sugar person, Hyperlipidemia person's long-term taking.
Description
Technical field
The invention belongs to technical field of food deep processing, and in particular to a kind of to have hypoglycemic, reducing blood lipid composition, drink
Material and its application.
Background technology
Now with dietary structure and living-pattern preservation, the incidence of disease rapid increase of diabetes.Clinically II type
Diabetic accounts for the 90% of diabetic's sum.It is mainly characterized by insulin resistance, the group such as liver, skeletal muscle, fat
Knit the intake to glucose to reduce, cause blood glucose levels to raise to form hyperglycaemia.Clinically, hyperglycaemia and high fat of blood
Interact.More than half diabetes patients are with disorders of lipid metabolism problem, that is, high fat of blood.Body is chronically at hyperglycaemia, height
Blood fat state may cause headstroke, limb necrosis, Eye disease, renal lesions, therefore actively be reduced while control blood glucose
Blood fat has positive effect.
At present, the medicine clinically to diabetes is generally chemical synthesis class medicine, such as sulfamido, biguanides, grape
Carbohydrase inhibitors, insulin sensitizer etc..But because the diabetes cause of disease, pathogenesis are not yet fully apparent from, diabetes patient needs
Long-term taking medicine, and chemical classes medicine long-term taking unavoidably has stronger side effect stronger, with liver renal toxicity, brings one
Serial adverse reaction.
The content of the invention
There is hypoglycemic, blood fat reducing function composition, beverage and its application, tool it is an object of the invention to provide a kind of
There is good hypoglycemic, blood fat reducing function.
In order to realize foregoing invention purpose, the present invention provides following technical scheme：
There is hypoglycemic, blood fat reducing function composition, including following weight percentage group the invention provides a kind of
The function raw material divided：Blue or green money willow extract 5~50%, Rhizoma Polygonati Odorati extract 10~30%, wrinkled papaya extract 10~40%, Huang
Essence extract 10~30%, kudzu root extract 10~30% and polysaccharide prebiotics 0.1%~15%.
It is preferred that, include the function raw material of following weight percentage：Blue or green money willow extract 20~40%, Rhizoma Polygonati Odorati extract
13~20%, wrinkled papaya extract 14~20%, Rhizoma Polygonati extract 14~25%, kudzu root extract 14~25% and polysaccharide
Prebiotics 2~10%.
It is preferred that, include the function raw material of following weight percentage：Blue or green money willow extract 30%, Rhizoma Polygonati Odorati extract
16%th, wrinkled papaya extract 18%, Rhizoma Polygonati extract 15%, kudzu root extract 18% and polysaccharide prebiotics 3%.
It is preferred that, the blue or green money willow extract is selenium-rich blue or green money willow extract or non-selenium-rich blue or green money willow extract.
It is preferred that, the mass concentration of selenium is 0.1~15mg/kg in the selenium-rich blue or green money willow extract.
It is preferred that, the polysaccharide prebiotics is the one or more in konjaku flour, Oligomeric manna sugar and FOS.
There is hypoglycemic, blood fat reducing function beverage, including described composition and auxiliary material present invention also offers a kind of.
It is preferred that, the auxiliary material includes water；The mass ratio of the composition and water is 1:50~300.
It is preferred that, the pH value of the beverage is 5.5~8.0.
The food or medicine of prevention and treatment hyperglycaemia and/or high fat of blood are being prepared present invention also offers described composition
Application in product.
There is hypoglycemic, blood fat reducing function composition, including following weight percentage group the invention provides a kind of
The function raw material divided：Blue or green money willow extract 5~50%, Rhizoma Polygonati Odorati extract 10~30%, wrinkled papaya extract 10~40%, Huang
Essence extract 10~30%, kudzu root extract 10~30%, polysaccharide prebiotics 0.1%~15%.Above-mentioned functions composition passes through
Suppress glycoside hydrolase, reduce glucose sugar intake, promote to recover the recovery of lesion islet function, repair cellular damage, promote pancreas
Island element secretion, improves Glucose tolerance test, collaboration reduction blood sugar level.By suppressing FAS genes and protein expression, reduce interior
Source property cholesterol biosynthesis, and cholesterol absorption is reduced, so as to reduce triglycerides, total cholesterol level, reach effect for reducing blood fat.
Meanwhile, blue or green money willow, polysaccharide prebiotics belong to new resource for food, radix polygonati officinalis, elephant skin wood in the composition that the present invention is provided
Melon, sealwort, the root of kudzu vine belong to medicine-food two-purpose food materials, and equal safety non-toxic is especially suitable for high blood glucose sugar person, Hyperlipidemia person and taken for a long time
With.
Beverage clear stable of the present invention, no obvious sediment.
Embodiment
There is hypoglycemic, blood fat reducing function composition, including following weight percentage group the invention provides a kind of
The function raw material divided：Blue or green money willow extract 5~50%, Rhizoma Polygonati Odorati extract 10~30%, wrinkled papaya extract 10~40%, Huang
Essence extract 10~30%, kudzu root extract 10~30% and polysaccharide prebiotics 0.1%~15%.
A kind of function raw material with hypoglycemic, blood fat reducing function beverage that the present invention is provided is extracted including blue or green money willow
Thing.Counted using composition weight as 100%, the percentage by weight of the blue or green money willow extract for 10~50%, more preferably 20~
40%, most preferably 30%.The blue or green money willow extract is selenium-rich blue or green money willow extract and/or non-selenium-rich blue or green money willow extract；
The mass concentration of selenium is preferably 0.1~15mg/kg in wherein described selenium-rich blue or green money willow extract, more preferably 1~10mg/
Kg, most preferably 5mg/kg.Blue or green money willow can significantly increase the glucose tolerance of alloxan diabetes mouse and promote disease
Become Pancreas Islet Structure functional rehabilitation, reduce fasting blood-glucose.Meanwhile, blue or green money willow may also suppress hyperlipemia in mice FAS genes and albumen
Matter is expressed, it will be apparent that is improved blood lipid metabolism and is improved antioxidant ability of organism.The source of the blue or green money willow extract is not special
Limitation, using blue or green money willow extract well-known to those skilled in the art.In the embodiment of the present invention, the blue or green money willow is extracted
Thing is purchased from Enshi Qingjiang Bioengineering Co., Ltd..
A kind of function raw material with hypoglycemic, blood fat reducing function beverage that the present invention is provided includes Rhizoma Polygonati Odorati extract.
Counted using composition weight as 100%, the percentage by weight of the Rhizoma Polygonati Odorati extract is 5~30%, preferably 13%~20%, more
Preferably 16%.Radix polygonati officinalis has had the history of thousands of years for treating diabetes.Rhizoma Polygonati Odorati extract can promote taking the photograph for glucose
Enter, promote muscle glycogen synthesis, enhancing peripheral tissues improve Glucose tolerance test to the susceptibility of insulin, reduce blood sugar level.
The source of the Rhizoma Polygonati Odorati extract is not particularly limited, using Rhizoma Polygonati Odorati extract well-known to those skilled in the art.This
In inventive embodiments, the Rhizoma Polygonati Odorati extract is purchased from Enshi Qingjiang Bioengineering Co., Ltd..
A kind of function raw material with hypoglycemic, blood fat reducing function beverage that the present invention is provided is extracted including wrinkled papaya
Thing.Counted using composition weight as 100%, the percentage by weight of the wrinkled papaya extract is 5~30%, preferably 14%~
20%, more preferably 18%.Wrinkled papaya extract can conspicuousness suppress α-glucose glycosidase, beta-glucosidase, and then subtract
Few grape sugar intake, while being obviously improved lipid metaboli, reduction serum total cholesterol, triglycerides, low-density lipoprotein courage are consolidated
Alcohol content, improves HDL-C content, reaches effect for reducing blood fat.The source of the wrinkled papaya extract does not have
It is specifically limited, using wrinkled papaya extract well-known to those skilled in the art.In the embodiment of the present invention, the elephant skin
Papaya extractives are purchased from Enshi Qingjiang Bioengineering Co., Ltd..
A kind of function raw material with hypoglycemic, blood fat reducing function beverage that the present invention is provided includes Rhizoma Polygonati extract.
Counted using composition weight as 100%, the percentage by weight of the Rhizoma Polygonati extract is 5~30%, preferably 14%~25%, more
Preferably 15%.Rhizoma Polygonati extract is the inhibitor of glycosylation damage, can reduce blood by promoting the secretion of insulin and C peptides
Sugar level.Rhizoma Polygonati extract can substantially suppress the speed limit enzymatic activity of Biosynthesis of cholesterol simultaneously, reduce endogenous cholesterol
Generation, so as to reduce blood lipid level.The source of the Rhizoma Polygonati extract is not particularly limited, ripe using those skilled in the art institute
The Rhizoma Polygonati extract known.In the embodiment of the present invention, the Rhizoma Polygonati extract is purchased from Enshi Qingjiang Bioengineering Co., Ltd..
A kind of function raw material with hypoglycemic, blood fat reducing function beverage that the present invention is provided includes kudzu root extract.
Counted using composition weight as 100%, the percentage by weight of the kudzu root extract is 5~30%, preferably 14~25%, more excellent
Elect 18% as.Kudzu root extract causes cellular damage to have obvious repair AGEP, can improve insulin resistance,
Strengthen insulin sensitivity, reduction blood glucose and blood fat.The source of the kudzu root extract is not particularly limited, using this area skill
Kudzu root extract known to art personnel.In the embodiment of the present invention, the kudzu root extract is purchased from the biological work in the Qingjian River of bestowing favour
Journey Co., Ltd.
It is prebiotic that a kind of function raw material with hypoglycemic, blood fat reducing function beverage that the present invention is provided includes polysaccharide
Member.Counted using composition weight as 100%, the percentage by weight of the polysaccharide prebiotics is 0.1%~15%, preferably 2~
10%, most preferably 3%.In the present invention, the polysaccharide prebiotics is one in konjaku flour, Oligomeric manna sugar, FOS
Plant or several.Cholic acid in the adsorbable enteric cavity of polysaccharide prebiotics, reduces the reabsorption of cholic acid, blocks the enteric cavity of cholesterol to follow
Ring, while reducing the absorptivity of dietary cholesterol, and then aids in reducing blood lipid.The source of the polysaccharide prebiotics does not have special limit
System, using polysaccharide prebiotics well-known to those skilled in the art.In the embodiment of the present invention, the polysaccharide prebiotics
Purchased from Shaanxi Sen Fu natural products Co., Ltd.
In the present invention, above-mentioned functions composition reduces glucose sugar intake by suppressing glycoside hydrolase, promotes to recover lesion
Islet function recovers, and repairs cellular damage, promotes insulin secretion, improves Glucose tolerance test, collaboration reduction blood sugar level.It is logical
Suppression FAS genes and protein expression are crossed, endogenous cholesterol synthesis is reduced, and reduces cholesterol absorption, so as to reduce glycerine
Three esters, total cholesterol level, reach effect for reducing blood fat.
There is hypoglycemic, blood fat reducing function beverage, including described composition and auxiliary material present invention also offers a kind of.
In the present invention, the auxiliary material preferably includes water；The composition and water mass ratio is preferably 50~300, more
Preferably 1:100~200, most preferably 1:175.
In the present invention, the pH value of the beverage is preferably 5.5~8.0, more preferably 6.0~7.0, most preferably 6.5.
In the present invention, the preparation method of the beverage preferably includes following steps：
1) above-mentioned composition is mixed with water, dissolves, obtain solution；
2) by the step 1) obtained solution regulation pH value, add sweetener；
3) by the step 2) obtained solution separation of solid and liquid obtains beverage
In the present invention, the step 2) described in sweetener preferably include neotame, honey element, Sucralose, maltitol,
One or more in D-sorbite, alitame, Abbas's sweet tea, steviol glycoside, acesulfame potassium, antierythrite, mogroside.Institute
Stating the addition quality of sweetener, to account for the percentage of solution be preferably 0.003%~5%.
In the present invention, the method for the dissolving is not particularly limited, using mixing well-known to those skilled in the art
Technical scheme.The method dissolved in the embodiment of the present invention is heating stirring, and the temperature of heating is 30~80 DEG C, more preferably
40~70 DEG C.
In the present invention, the method for the separation of solid and liquid is not particularly limited, using well-known to those skilled in the art solid
The technical scheme of liquid separation.In the embodiment of the present invention, the separation of solid and liquid is realized using the method for filtering.
In the present invention, homogeneous is further preferably included after the separation of solid and liquid, sterilizing is filling, obtains beverage.
In the present invention, the preferred high pressure steam sterilization of method of the sterilizing, ultra high temperature short time sterilization, membrane filtration is degerming, micro-
Ripple sterilizes or radiation sterilization.
In the present invention, the preferred vial of filling container, PET bottle, the one or more in metal can.
In the present invention, the solution colour stable homogeneous that the flavored condiment is obtained is added, it is distinctive with plant beverage
Natural faint scent, outward appearance is not stratified without obvious sediment, with obvious hypoglycemic, blood fat reducing function.
Obvious hypoglycemic, reducing blood lipid is had effects that based on the composition, present invention also offers described composition
Application in the food or medicine of prevention and treatment hyperglycaemia and/or high fat of blood is prepared.
A kind of hypoglycemic, reducing blood lipid composition, beverage and its application provided with reference to embodiment the present invention is entered
Row detailed description, but they can not be interpreted as limiting the scope of the present invention.
Embodiment 1
A certain amount of composition is accurately weighed, is by weight percentage blue or green money willow extract 5%, Rhizoma Polygonati Odorati extract 15%, wrinkle
Skin papaya extractives 32%, Rhizoma Polygonati extract 30%, kudzu root extract 10%, konjaku flour 8%.According to the quality of composition and water
Than for 1:50 amount adds water, is dissolved at a temperature of 80 DEG C.Dilution is adjusted to the neotame of addition 0.003% after pH to 5.5,
0.01% steviol glycoside, and filter homogeneous.Resulting solution is sterilized under the conditions of 121 DEG C 10min progress high pressure steam sterilizations,
It is filling enter vial produce with hypoglycemic, hypolipemic function beverage.
Embodiment 2
Accurately weigh a certain amount of composition, be by weight percentage, blue or green money willow extract 50%, Rhizoma Polygonati Odorati extract 10%,
Wrinkled papaya extract 10%, Rhizoma Polygonati extract 10%, kudzu root extract 15%, konjaku flour 5%.According to the matter of composition and water
Amount is than being 1:200 amount adds water, is dissolved at a temperature of 80 DEG C.Dilution is adjusted to the sweet tea of addition 0.05% after pH to 7.5
Sweet element, and filter homogeneous.The ultra high temperature short time sterilization under the conditions of sterilizing 10s under the conditions of 135 DEG C by resulting solution, it is filling enter glass
Bottle is produced with hypoglycemic, hypolipemic function beverage.
Embodiment 3
Accurately weigh a certain amount of composition, be by weight percentage, blue or green money willow extract 20%, Rhizoma Polygonati Odorati extract 10%,
Wrinkled papaya extract 15%, Rhizoma Polygonati extract 10%, kudzu root extract 30%, FOS 15%.According to composition and water
Mass ratio be 1:250 amount adds water, is dissolved at a temperature of 55 DEG C.0.022% is added after dilution is adjusted into pH to 8.0
Sucralose, and filter homogeneous.Resulting solution membrane filtration is sterilized, it is filling enter metal bottle produce with hypoglycemic, reducing blood lipid
The beverage of function.
Embodiment 4
Accurately weigh a certain amount of composition, be by weight percentage, blue or green money willow extract 33%, Rhizoma Polygonati Odorati extract 15%,
Wrinkled papaya extract 14%, Rhizoma Polygonati extract 12%, kudzu root extract 13%, FOS 13%.According to composition and water
Mass ratio be 1:150 amount adds water, is dissolved at a temperature of 65 DEG C.Dilution is adjusted to the wheat of addition 3% after pH to 6.8
Bud sugar alcohol, and filter homogeneous.By resulting solution film microwave sterilization, it is filling enter metal bottle produce with hypoglycemic, hypolipemic function
Beverage.
Embodiment 5
Accurately weigh a certain amount of composition, be by weight percentage, blue or green money willow extract 16%, Rhizoma Polygonati Odorati extract 11%,
Wrinkled papaya extract 40%, Rhizoma Polygonati extract 14.5%, kudzu root extract 18%, Oligomeric manna sugar 0.5%.According to composition
Mass ratio with water is 1:300 amount adds water, is dissolved at a temperature of 70 DEG C.5% is added after dilution is adjusted into pH to 7.5
D-sorbite, and filter homogeneous.By resulting solution radiation sterilization, it is filling enter PET bottle produce with hypoglycemic, hypolipemic function
Beverage.
Embodiment 6
Accurately weigh a certain amount of composition, be by weight percentage, blue or green money willow extract 27%, Rhizoma Polygonati Odorati extract 30%,
Wrinkled papaya extract 15%, Rhizoma Polygonati extract 12%, kudzu root extract 12%, konjaku flour 4%.According to the matter of composition and water
Amount is than being 1:200 amount adds water, is dissolved at a temperature of 70 DEG C.By dilution adjust pH to 6.5 after add 0.003% Ah
Power sweet tea, and filter homogeneous.20min that resulting solution is sterilized under the conditions of 117 DEG C carries out high pressure steam sterilization, it is filling enter metal bottle
Produce with hypoglycemic, hypolipemic function beverage.
Embodiment 7
Accurately weigh a certain amount of composition, be by weight percentage, blue or green money willow extract 23%, Rhizoma Polygonati Odorati extract 15%,
Wrinkled papaya extract 26%, Rhizoma Polygonati extract 15%, kudzu root extract 12%, konjaku flour 9%.According to the matter of composition and water
Amount is than being 1:155 amount adds water, is dissolved at a temperature of 60 DEG C.By dilution adjust pH to 6.3 after add 0.003% Ah
Power sweet tea, 5% antierythrite, and filter homogeneous.8s that resulting solution is sterilized under the conditions of 135 DEG C carries out superhigh temperature and instantaneously gone out
Bacterium, it is filling enter vial produce with hypoglycemic, hypolipemic function beverage.
Embodiment 8
Accurately weigh a certain amount of composition, be by weight percentage, blue or green money willow extract 22%, Rhizoma Polygonati Odorati extract 17%,
Wrinkled papaya extract 40%, Rhizoma Polygonati extract 10.5%, kudzu root extract 10.4%, Oligomeric manna sugar 0.1%.According to combination
The mass ratio of thing and water is 1:175 amount adds water, is dissolved at a temperature of 75 DEG C.Dilution is adjusted and added after pH to 6.5
0.003% alitame, 0.02% antierythrite, and filter homogeneous.Resulting solution membrane filtration is sterilized, it is filling enter PET bottle
Produce with hypoglycemic, hypolipemic function beverage.
Embodiment 9
Accurately weigh a certain amount of composition, be by weight percentage, blue or green money willow extract 35%, Rhizoma Polygonati Odorati extract 12%,
Wrinkled papaya extract 14%, Rhizoma Polygonati extract 15%, kudzu root extract 15%, FOS 9%.According to composition and water
Mass ratio is 1:200 amount adds water, is dissolved at a temperature of 45 DEG C.Dilution is adjusted 0.02% is added after pH to 7.3
Acesulfame potassium, 2% xylitol, and filter homogeneous.By resulting solution microwave sterilization, it is filling enter metal bottle produce with it is hypoglycemic,
The beverage of hypolipemic function.
Embodiment 10
Accurately weigh a certain amount of composition, be by weight percentage, blue or green money willow extract 42%, Rhizoma Polygonati Odorati extract 12%,
Wrinkled papaya extract 12%, Rhizoma Polygonati extract 12%, kudzu root extract 18%, konjaku flour 4%.According to the matter of composition and water
Amount is than being 1:130 amount adds water, is dissolved at a temperature of 55 DEG C.Dilution is adjusted to the peace of addition 0.015% after pH to 7.1
Match honey, 2% Sucralose, 0.5% mogroside, and filter homogeneous.By resulting solution radiation sterilization, it is filling enter PET
Bottle is produced with hypoglycemic, hypolipemic function beverage.
Embodiment 11~20
There is a kind of with the preparation of embodiment 1~10 hypoglycemic, blood fat reducing function beverage to carry out mouse long term toxicity examination
Test respectively embodiment 11-20.
Healthy Wistar rats 200 are taken, male and female half and half are randomly divided into 2 groups, every group 10, be respectively by embodiment system
The given low of standby beverage is adjusted to experimental group (0.9g/kg) and separately sets blank group as control.Each experimental group carries out gavage, often
Day gavage 2 times, weekly gavage 6 days (stopping gavage one day on the 7th day), continuous 12 weeks.Blank group gives isodose distilled water.
Weighed weekly in experimentation, and observe each group activities in rats, hair color, feed drinking-water, state of mind etc..Test after terminating to big
The toxic reaction that mouse carries out hematology, blood biochemical analysis index checking is likely to occur with analyzing, while putting to death and dissecting rat, takes
Main organs are weighed, and calculate organ coefficient, and make histopathologic examination to main organs.
Experimental result is shown, during gastric infusion, and activity, hair color, feed drinking-water, state of mind of each group rat etc. are not
See obvious anomalous variation, body weight, food-intake and the hematology of each dosage group, blood biochemical analysis index and organ coefficient
Significant change is showed no compared with blank group, the histopathologic examination of rat main organs does not show any abnormalities.
Embodiment 21~30
Beverage prepared by embodiment 1~10 is concentrated and dried to powder, and powder given low is adjusted to 0.9g/kg, entered
The hypoglycemic experiment of row, detection each group mouse blood sugar TG-AUC, glycated serum protein content, hepatic glycogen content, is implemented
Example 21~30.
Health male C57 mouse 130 are taken, common to maintain feed to adapt to feed 5 days, fasting be can't help water and be stayed overnight, and take tail blood,
Determine on an empty stomach i.e. to (0 hour) blood glucose value before glucose, to determining 0.5,2 hours blood glucose values after 2.5g/kgBW glucose, as
The batch animal basic value.With 0 hours blood glucose 13 groups of level point, i.e., 1 blank control group, 1 model control group, 1 sun
Property medicine group (control drug：Diabetes pill), 10 experimental groups (given low is 0.9g/kg).Each experimental group respectively give by gavage
The not given the test agent of be the same as Example, positive medicine group gives 51.4mg/100g diabetes pill, and model control group gives same volume solvent,
Continuous 42 days.Blank group is given maintenance material and raised, and other groups give high lipid food.After 4 weeks, positive medicine group, model control group, reality
Test group and give streptozotocin 40mg/kg intraperitoneal injections respectively on the basis of high lipid food, blank group gives the lemon of same volume
Fasting blood sugar is surveyed, then inject once in acid salt solution, interval after three days.Each group mouse fasting be can't help water and be stayed overnight, and determine fasting blood
Sugar is i.e. to (0 hour) blood glucose value before glucose, and experimental group gives various concentrations given the test agent, and it is molten that model control group gives same volume
Agent, blank control group is not processed, each group oral administration of glucose 2.5g/kgBW after 15 minutes, is determined to each group after glucose
0.5th, the blood glucose value of 2 hours, calculates Area under the curve of blood glucose (AUC).After last dose, all mouse commonly maintain material to feed 2d
Fasting 12h afterwards.Pluck eyeball and take glycated serum protein (GSP) content in blood, centrifugal blood separation serum, detection serum.Put to death small
Clip mouse liver tissue after mouse, detects mouse hepatic glycogen content.
Each group mouse blood sugar TG-AUC, glycated serum protein content, hepatic glycogen content are shown in Table 1 respectively.
The hypoglycemic experimental result of mouse of the embodiment 21~30 of table 1
As shown in Table 1, mouse blood sugar TG-AUC, serum GSP contents, hepatic glycogen content show embodiment 1~10
Obtained beverage is respectively provided with good effect of lowering blood sugar.
Embodiment 31-40
The embodiment 1-10 beverages prepared are concentrated and dried to powder, powder given low is adjusted to 0.9g/kg, carried out
T-CHOL (TC), triglycerides (TG), HDL-C in lipid-lowering test, detection each group mice serum
(HDL-C), LDL-C (LDL-C) content, obtains embodiment 31~40.
Each group mouse T-CHOL (TC), triglycerides (TG), HDL-C (HDL-C), low density lipoprotein
Protein cholesterol (LDL-C) content is shown in Table 2 respectively.
The mouse lipid-lowering test result of the embodiment 31~40 of table 2
As shown in Table 2, TC, TG, HDL-C, LDL-C content show, embodiment 1-10, which obtains beverage, substantially drop blood
Fat effect.
As seen from the above embodiment, a kind of hypoglycemic, reducing blood lipid beverage for providing of the present invention, have significantly it is hypoglycemic,
Lipid-lowering effect.And testing proves that the beverage that the present invention is provided has no toxic side effect to mouse, is adapted to long-term taking.
Described above is only the preferred embodiment of the present invention, it is noted that for the ordinary skill people of the art
For member, under the premise without departing from the principles of the invention, some improvements and modifications can also be made, these improvements and modifications also should
It is considered as protection scope of the present invention.
Claims (10)
1. a kind of have hypoglycemic, blood fat reducing function composition, it is characterised in that including following weight percentage component
Function raw material：Blue or green money willow extract 5~50%, Rhizoma Polygonati Odorati extract 10~30%, wrinkled papaya extract 10~40%, sealwort are carried
Take thing 10~30%, kudzu root extract 10~30% and polysaccharide prebiotics 0.1%~15%.
2. composition according to claim 1, it is characterised in that the function raw material including following weight percentage：It is blue or green
Money willow extract 20~40%, Rhizoma Polygonati Odorati extract 13~20%, wrinkled papaya extract 14~20%, Rhizoma Polygonati extract 14~
25%th, kudzu root extract 14~25% and polysaccharide prebiotics 2~10%.
3. composition according to claim 1, it is characterised in that the function raw material including following weight percentage：It is blue or green
Money willow extract 30%, Rhizoma Polygonati Odorati extract 16%, wrinkled papaya extract 18%, Rhizoma Polygonati extract 15%, kudzu root extract
18% and polysaccharide prebiotics 3%.
4. the composition according to claims 1 to 3 any one, it is characterised in that the blue or green money willow extract is selenium-rich
Blue or green money willow extract or non-selenium-rich blue or green money willow extract.
5. composition according to claim 4, it is characterised in that the mass concentration of selenium in the selenium-rich blue or green money willow extract
For 0.1~15mg/kg.
6. the composition according to claims 1 to 3 any one, it is characterised in that the polysaccharide prebiotics is konjaku
One or more in powder, Oligomeric manna sugar and FOS.
7. a kind of have hypoglycemic, blood fat reducing function beverage, it is characterised in that including described in claim 1~6 any one
Composition and auxiliary material.
8. beverage according to claim 7, it is characterised in that the auxiliary material includes water；The quality of the composition and water
Than for 1:50~300.
9. beverage according to claim 7, it is characterised in that the pH value of the beverage is 5.5~8.0.
10. the composition described in claim 1~6 any one is preparing the food of prevention and treatment hyperglycaemia and/or high fat of blood
Application in product or medicine.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710522657.8A CN107280006A (en) | 2017-06-30 | 2017-06-30 | It is a kind of that there is hypoglycemic, blood fat reducing function composition, beverage and its application |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710522657.8A CN107280006A (en) | 2017-06-30 | 2017-06-30 | It is a kind of that there is hypoglycemic, blood fat reducing function composition, beverage and its application |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107280006A true CN107280006A (en) | 2017-10-24 |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110731509A (en) * | 2019-12-07 | 2020-01-31 | 张志红 | A health product containing prebiotics for lowering blood sugar and blood lipid, and its preparation method |
| CN112120204A (en) * | 2020-10-27 | 2020-12-25 | 湖南华诚生物资源股份有限公司 | Sweet composition for reducing blood fat and preparation method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN106177433A (en) * | 2015-04-29 | 2016-12-07 | 无限极（中国）有限公司 | A kind of Hyperglycemic health care compositions comprising leaf of Cyclocarya paliurus Iljinskaja, Radix Puerariae and Rhizoma Polygonati Odorati |
| CN106538914A (en) * | 2016-11-23 | 2017-03-29 | 武汉百思凯瑞纳米科技有限公司 | It is a kind of with blood sugar lowering, the beverage of blood fat reducing function and preparation method thereof |
| CN106616132A (en) * | 2016-12-01 | 2017-05-10 | 恩施硒多宝饮品有限公司 | Selenium-enriched original plant beverage and preparation method thereof |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106177433A (en) * | 2015-04-29 | 2016-12-07 | 无限极（中国）有限公司 | A kind of Hyperglycemic health care compositions comprising leaf of Cyclocarya paliurus Iljinskaja, Radix Puerariae and Rhizoma Polygonati Odorati |
| CN106538914A (en) * | 2016-11-23 | 2017-03-29 | 武汉百思凯瑞纳米科技有限公司 | It is a kind of with blood sugar lowering, the beverage of blood fat reducing function and preparation method thereof |
| CN106616132A (en) * | 2016-12-01 | 2017-05-10 | 恩施硒多宝饮品有限公司 | Selenium-enriched original plant beverage and preparation method thereof |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110731509A (en) * | 2019-12-07 | 2020-01-31 | 张志红 | A health product containing prebiotics for lowering blood sugar and blood lipid, and its preparation method |
| CN112120204A (en) * | 2020-10-27 | 2020-12-25 | 湖南华诚生物资源股份有限公司 | Sweet composition for reducing blood fat and preparation method thereof |
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