CN107260818B - Skin-moistening and itching-relieving ointment - Google Patents

Abstract

The invention relates to a skin-moistening and itching-relieving ointment which is prepared from the following raw material medicines: catechu, Calomelas, Borneolum Syntheticum, radix Angelicae sinensis, Saviae Miltiorrhizae radix, Carthami flos, lignum sappan, caulis Spatholobi, radix Angelicae Dahuricae, pollen, Coptidis rhizoma, rhizoma Ligustici Chuanxiong, Cera flava, and oleum Sesami. The skin-moistening and itching-relieving cream provided by the invention is prepared from raw materials including catechu, calomel, borneol, angelica, salvia miltiorrhiza, safflower, sappan wood, suberect spatholobus stem, angelica dahurica, pollen, coptis chinensis, ligusticum wallichii, beeswax and sesame oil, has the effects of clearing heat, cooling blood, detoxifying, moistening skin, killing parasites and relieving itching, is suitable for treating common skin diseases of pityriasis and psoriasis, adopts less medicinal flavors, enhances the effects of various medicinal materials on the aspect of being used for the skin diseases through reasonable compatibility, and shows obvious synergistic effect.

Description

Skin-moistening and itching-relieving ointment

Technical Field

The invention relates to a skin-moistening and itching-relieving preparation, in particular to a skin-moistening and itching-relieving ointment.

Background

The psoriasis is common skin diseases in daily life, is commonly caused by genetic factors and environmental factors, is the leading factor of the diseases due to the change of the living environment and the dietary habits of people in recent years, is long in course of treatment of the diseases by western medicine, has no obvious effect, is easy to relapse, and brings great influence to the body and the mind of a patient. The traditional Chinese medicine has stable curative effect, difficult relapse, small side effect and obvious advantages in the process of treating the diseases. The development of external traditional Chinese medicine for shortening the treatment course has important significance for treatment.

Disclosure of Invention

The technical problem to be solved by the invention is as follows: the skin-moistening and itching-relieving ointment has the effects of clearing heat, cooling blood, detoxifying, moistening skin, killing parasites and relieving itching, and is suitable for treating common skin diseases of pityriasis and psoriasis.

The technical scheme adopted by the invention for solving the problems is as follows:

the skin-moistening itching-relieving ointment is prepared from the following raw material medicines: catechu, Calomelas, Borneolum Syntheticum, radix Angelicae sinensis, Saviae Miltiorrhizae radix, Carthami flos, lignum sappan, caulis Spatholobi, radix Angelicae Dahuricae, pollen, Coptidis rhizoma, rhizoma Ligustici Chuanxiong, Cera flava, and oleum Sesami.

Preferably, the traditional Chinese medicine is prepared from the following raw material medicines: 25-35g of catechu, 25-35g of calomel, 5-7g of borneol, 25-35g of angelica, 25-35g of salvia miltiorrhiza, 50-70g of safflower, 35-50g of sappan wood, 25-40g of suberect spatholobus stem, 25-40g of angelica dahurica, 25-40g of pollen, 30-45g of coptis chinensis, 25-35g of szechuan lovage rhizome, 1000g of beewax and 2000g of sesame oil.

Preferably, the traditional Chinese medicine is prepared from the following raw material medicines: 30g of catechu, 30g of calomel, 5g of borneol, 30g of angelica, 30g of salvia miltiorrhiza, 60g of safflower, 40g of sappan wood, 30g of suberect spatholobus stem, 30g of angelica dahurica, 30g of pollen, 40g of coptis chinensis, 30g of ligusticum wallichii, 1000g of beewax and 2000g of sesame oil.

The preparation method of the skin-moistening and itching-relieving cream comprises the following steps:

1) soaking: weighing the prepared medicines according to the selected prescription, and soaking the medicines in sesame oil; the proportion of the medicinal oil is three to one, and the soaking time is seven days in spring and autumn, five days in summer and ten days in winter;

2) explosive oil boiling: putting the sesame oil and the soaked medicines into a pot, starting to use strong fire for twenty minutes, then changing to slow fire, turning over and pressing in the pot with a locust stick and slightly stirring during the period, and immediately taking the pot out of the fire when the medicines are boiled to be scorched and sink to the bottom of oil;

3) dissolving beeswax: pouring the medicinal oil into an iron basin filled with beeswax through a 60-mesh sieve, continuously stirring until the beeswax is completely melted, when the temperature is reduced to 60 ℃, grinding the catechu, the calomel and the borneol into fine powder, sieving the fine powder through a 150-mesh basket, adding the catechu, the calomel and the borneol powder, uniformly stirring, and waiting for complete cooling;

4) placing the iron basin containing the ointment on a gas stove after two days, heating to melt, filtering to another iron basin through a 150-mesh iron screen, cooling to obtain skin-moistening and itching-relieving ointment, and placing in special small containers with special tools respectively for later use.

The skin-moistening and itching-relieving cream provided by the invention is prepared from raw materials including catechu, calomel, borneol, angelica, salvia miltiorrhiza, safflower, sappan wood, suberect spatholobus stem, angelica dahurica, pollen, coptis chinensis, ligusticum wallichii, beeswax and sesame oil, has the effects of clearing heat, cooling blood, detoxifying, moistening skin, killing parasites and relieving itching, is suitable for treating common skin diseases of pityriasis and psoriasis, adopts less medicinal flavors, enhances the effects of various medicinal materials on the aspect of being used for the skin diseases through reasonable compatibility, and shows obvious synergistic effect.

Detailed Description

The present invention will be further described with reference to the following examples.

Example 1 preparation of skin moisturizing and antipruritic cream

The formula is as follows: 30g of catechu, 30g of calomel, 5g of borneol, 30g of angelica, 30g of salvia miltiorrhiza, 60g of safflower, 40g of sappan wood, 30g of suberect spatholobus stem, 30g of angelica dahurica, 30g of pollen, 40g of coptis chinensis, 30g of ligusticum wallichii, 1000g of beewax and 2000g of sesame oil.

The preparation method comprises the following steps: 1) soaking: weighing the prepared medicines according to the selected prescription, and soaking the medicines in sesame oil; the proportion of the medicinal oil is three to one, and the soaking time is seven days in spring and autumn, five days in summer and ten days in winter;

2) explosive oil boiling: putting the sesame oil and the soaked medicines into a pot, starting to use strong fire for twenty minutes, then changing to slow fire, turning over and pressing in the pot with a locust stick and slightly stirring during the period, and immediately taking the pot out of the fire when the medicines are boiled to be scorched and sink to the bottom of oil;

3) dissolving beeswax: pouring the medicinal oil into an iron basin filled with beeswax through a 60-mesh sieve, continuously stirring until the beeswax is completely melted, when the temperature is reduced to 60 ℃, grinding the catechu, the calomel and the borneol into fine powder, sieving the fine powder through a 150-mesh basket, adding the catechu, the calomel and the borneol powder, uniformly stirring, and waiting for complete cooling;

4) placing the iron basin containing the ointment on a gas stove after two days, heating to melt, filtering to another iron basin through a 150-mesh iron screen, cooling to obtain skin-moistening and itching-relieving ointment, and placing in special small containers with special tools respectively for later use.

Example 2 preparation of skin moisturizing and antipruritic cream

The formula is as follows: 31g of catechu, 31g of calomel, 5g of borneol, 32g of angelica, 32g of salvia miltiorrhiza, 58g of safflower, 38g of sappan wood, 35g of suberect spatholobus stem, 28g of angelica dahurica, 28g of pollen, 40g of coptis chinensis, 30g of ligusticum wallichii, 1000g of beewax and 2000g of sesame oil.

The preparation method is the same as example 1.

Example 3 preparation of skin moisturizing and antipruritic cream

The formula is as follows: the traditional Chinese medicine composition comprises, by weight, 32g of catechu, 30g of calomel, 5g of borneol, 32g of angelica, 30g of salvia miltiorrhiza, 62g of safflower, 40g of sappan wood, 32g of suberect spatholobus stem, 32g of angelica dahurica, 32g of pollen, 40g of coptis chinensis, 32g of ligusticum wallichii, 1000g of beewax and 2000g of sesame oil.

The preparation method is the same as example 1.

The observation of the curative effect of a specific case:

experimental example 1

Patient Li A, male, 19 years old, No. 3 at 12 months 2015

The main complaints are: the skin of the lateral sides of the crus on both sides of the patient is dry and has no perspiration for more than 5 years in summer

The current medical history: the skin on the outer sides of the shanks on both sides is dry and rough 5 years ago, the patients have slight perspiration in summer and are not paid attention to all the time, large yellow brown scales appear gradually in three years, the skin care products are automatically used for external application, obvious relief is not realized, and the patients can see a doctor in a local county hospital and are checked in a laboratory: normal blood and urine, pathological detection of local skin tissues, slightly thick skin granular layer, slightly thickened acantho, keratotic plug in hair follicle hole and sweat gland and reduced sebaceous gland number. Diagnosing as ordinary ichthyosis. The 10mg of the abamectin A ester is orally taken every day, and the tretinoin emulsifiable paste and the dexamethasone ointment are externally smeared twice a day in a combined way. After 3 months of treatment, the symptoms of dryness were relieved, but the scales remained evident. Treatment was performed everywhere.

History of the past: no past medical history, mild food preference for spicy and thick taste

Family history: has family genetic disease history

Physical examination: t: 36.5P: 75 times/min R: 120/75mmHg, spiritual, dietetic, clear language, cooperative diagnosis, round and big pupils, no abnormality of superficial lymph nodes of the whole body, percussion and clear sound of the two lungs, normal respiration, no rale, normal heart point pulsation and heart voiced sound boundary, regular rhythm, no noise, soft abdomen, no tenderness, percussion pain and rebound pain. Liver, spleen and kidney were not monitored. The spleen and kidney areas on both sides have no pressure pain or percussion pain. Normal spine, rough skin on the sides of calf, fibula on both sides, large yellow-brown scales, and slightly free edges.

And (3) diagnosis: pityriasis

The tongue of the patient is reddish after the patient is hospitalized, the pulse is thin, the body constitution is thin, the patient is addicted to spicy and thick taste after the patient is hospitalized, and the patient belongs to the problems of congenital deficiency, acquired spleen and stomach disorder and nutrient and blood deficiency, so that the blood deficiency can cause wind and dryness, and the skin is not nourished. The syndrome is distinguished as blood deficiency and wind dryness, the treatment selects the modified blood-generating skin-moistening decoction of the formulas for nourishing blood, dispelling wind and moistening dryness, the skin-moistening itching-relieving ointment prepared by external use is uniformly smeared on the affected part for three times a day, and the treatment lasts twenty days. Twenty days later, the rough feeling of the skin of the lower leg of the patient is obviously relieved, the free edge of the scale is gradually attached to the skin, but the fish scale is still obvious, the patient feels thirst at night, the tongue is red and dry, the tongue coating is thin and yellow, and the syndrome is yin deficiency and dryness heat, the original oral prescription is added with the decoction of four ingredients to nourish yin and moisten dryness, and then the skin moistening and itching relieving ointment is externally applied. The treatment lasts twenty days. After twenty days, the skin of the affected part is smooth, the original scaly skin is slightly hyperpigmented, tiny vellus hairs penetrate or curl on the sweat gland part, and the traditional Chinese medicine and the external liniment are taken to moisten the skin and relieve itching to be solidified for twenty days. The affected part skin is basically the same as the normal skin after the double diagnosis for twenty days. Belongs to the law of light diet, warm water bath and rest of patients. The follow-up after one month had no abnormal symptoms.

Experimental example 2

Patient Cao Zhi, male, 24 years old, No. 11/2016, 2 visit

The main complaints are: the red plaque appears on the whole body of the patient with the desquamation aggravated for eight years

The current medical history: the patients have several red patches with different soybean sizes on the chest due to the prolonged common cold for half a month before the recovery, and have the disadvantages of thin crumbs and pruritus. The treatment is not taken into consideration, the area of an affected part is slightly enlarged in nearly two years, the affected part is gradually expanded to two upper limbs, an antiallergic dexamethasone ointment is bought and smeared, a cold is suffered before one month, plaques are rapidly expanded to the whole body, scales are thickened, pruritus is severe, rest is influenced, and the treatment is carried out in a people hospital in a lotus region along with pathological detection: the affected part has hyperkeratosis with parakeratosis, obviously reduced granular layer, thickened spinous layer, and pestle-shaped dermal papilla, and its upper capillary vessel dilates and becomes congested. The psoriasis vulgaris is diagnosed, 2.5 mg/day/three times of methotrexate serving as an immunosuppressant is administered, 1 mg/day/two times of abamectin A ester is orally taken, dexamethasone cream is externally applied to severe parts, 2% anthrin ointment is externally applied to mild parts, and narrow-wave UVB illumination is applied locally for 3 times per week. After one month of treatment, pruritus is relieved, but scales are still obvious, and the treatment is carried out at all places.

History of the past: the past history shows that the patient is adept to spicy food and has irregular rest

Genetic history: has family genetic history

Physical examination: t: 36.4P: 70 times/min R: 120/70mmHg, spiritual, dietetic, clear language, cooperative diagnosis, normal and large pupils, no abnormality of superficial lymph nodes of the whole body, percussion and clear sound of the two lungs, normal respiration, no rale, normal heart point pulsation and heart voiced sound boundary, regular rhythm, no noise, soft abdomen, no tenderness, percussion pain and rebound pain. Liver, spleen and kidney were not monitored. The spleen and kidney areas on both sides have no pressure pain or percussion pain. The spine is normal, the skin of the whole body is scattered in erythema, silvery white scales are covered on the skin, the phenomenon of wax drop is caused by light scraping, a reddish luminescent semitransparent film (film phenomenon) can be seen when the scales are scraped, and punctate bleeding (Auspete characteristic) can be seen when the film is peeled off.

And (3) diagnosis: psoriasis vulgaris

The patient has a pale red tongue with thick and greasy coating, a soft and thready pulse, internal heat due to factors, addiction to spicy food and mental stress, stagnation of qi and blood, transformation of fire for a long time, external attack on the skin and repeated affection of exogenous pathogenic factors to cause diseases. The exterior-applied skin-moistening itching-relieving ointment is prepared by mixing the above raw materials, adding a certain amount of the mixture into a formula, and uniformly stirring, and then uniformly stirring. After ten days, the scales on the severe parts of the skin chest of the affected part become thinner and slightly convex at the periphery, the scales on the slight parts of the limbs disappear, the bright red skin turns to light white, patients have vexation, insomnia and dreamful sleep, bitter taste and dry throat, the symptoms are distinguished as long-time disease impairment of yin, heat enters nutrient blood, nutrient clearing decoction and rhinoceros horn and rehmannia decoction are added and reduced, the medicine residue is decocted outside the affected part to promote the expansion of pores, and then the skin moistening and itching relieving ointment of the external preparation is applied to facilitate the better absorption of the medicine effect (note: at this time, the medicine is applied in a closed space to avoid the invasion of wind evil into the expanded skin of the striae), and the medicine is continuously applied for. After the patient is subjected to the double-diagnosis ten days later, the affected part of the four limbs has basically recovered normal skin color, the serious part of the chest has no scales, the convex part has flat and is still reddish, and the patient occasionally has slight pruritus at night. The prescription selects the prescription of the Chinese angelica drink for nourishing blood, moistening skin and dispelling wind and arresting itching, is modified to be taken orally, one dose is taken every day, ten doses are taken continuously, and the prescription of the external liniment, namely the skin-moistening and itching-relieving ointment is the same as the method. After ten days, the affected part has completely recovered. The spicy food is prohibited for a long time, the rest is regular, and the emotion is kept smooth. The traditional Chinese medicine for oral administration is reduced, and then the preparation of the skin-moistening and itching-relieving ointment is applied to nourish the skin, so that the bottom skin is completely repaired. The follow-up visit after one month has no recurrence.

The specific embodiments of the present invention should not be construed as limiting the invention, and all similar constructions and modifications utilizing the same are intended to be included within the scope of the present invention.

Claims (3)

1. The skin-moistening and itching-relieving cream is characterized in that: is prepared from the following raw material medicaments: 25-35g of catechu, 25-35g of calomel, 5-7g of borneol, 25-35g of angelica, 25-35g of salvia miltiorrhiza, 50-70g of safflower, 35-50g of sappan wood, 25-40g of suberect spatholobus stem, 25-40g of angelica dahurica, 25-40g of pollen, 30-45g of coptis chinensis, 25-35g of szechuan lovage rhizome, 1000g of beewax and 2000g of sesame oil.

2. The skin-moistening and itching-relieving cream according to claim 1, characterized in that: is prepared from the following raw material medicaments: 30g of catechu, 30g of calomel, 5g of borneol, 30g of angelica, 30g of salvia miltiorrhiza, 60g of safflower, 40g of sappan wood, 30g of suberect spatholobus stem, 30g of angelica dahurica, 30g of pollen, 40g of coptis chinensis, 30g of ligusticum wallichii, 1000g of beewax and 2000g of sesame oil.

3. A method for preparing a skin-moisturizing and itching-relieving cream according to any one of claims 1 to 2, wherein the skin-moisturizing and itching-relieving cream comprises the following steps: 1) soaking: weighing the prepared medicines according to the selected prescription, and soaking the medicines in sesame oil; the proportion of the medicinal oil is three to one, and the soaking time is seven days in spring and autumn, five days in summer and ten days in winter;

2) explosive oil boiling: putting the sesame oil and the soaked medicines into a pot, starting to use strong fire for twenty minutes, then changing to slow fire, turning over and pressing in the pot with a locust stick and slightly stirring during the period, and immediately taking the pot out of the fire when the medicines are boiled to be scorched and sink to the bottom of oil;

3) dissolving beeswax: pouring the medicinal oil into an iron basin filled with beeswax through a 60-mesh sieve, continuously stirring until the beeswax is completely melted, when the temperature is reduced to 60 ℃, grinding the catechu, the calomel and the borneol into fine powder, sieving the fine powder through a 150-mesh basket, adding the catechu, the calomel and the borneol powder, uniformly stirring, and waiting for complete cooling;

4) placing the iron basin containing the ointment on a gas stove after two days, heating to melt, filtering to another iron basin through a 150-mesh iron screen, cooling to obtain skin-moistening and itching-relieving ointment, and placing in special small containers with special tools respectively for later use.