CN107224572A - A kind of functions of removing chloasma capsule and preparation method thereof - Google Patents
A kind of functions of removing chloasma capsule and preparation method thereof Download PDFInfo
- Publication number
- CN107224572A CN107224572A CN201710445026.0A CN201710445026A CN107224572A CN 107224572 A CN107224572 A CN 107224572A CN 201710445026 A CN201710445026 A CN 201710445026A CN 107224572 A CN107224572 A CN 107224572A
- Authority
- CN
- China
- Prior art keywords
- parts
- extract
- functions
- capsule
- weight
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/537—Salvia (sage)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/16—Ginkgophyta, e.g. Ginkgoaceae (Ginkgo family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/738—Rosa (rose)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/87—Vitaceae or Ampelidaceae (Vine or Grape family), e.g. wine grapes, muscadine or peppervine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Medical Informatics (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a kind of functions of removing chloasma capsule and preparation method thereof.It includes the raw material of following parts by weight：100 200 parts of Salvia root P.E, 100 150 parts of angelica extract, 60 100 parts of Flos Rosae Rugosae extract, 60 100 parts of collagen, 25 50 parts of grape seed extract, 50 80 parts of ginkgo biloba extract, 20 35 parts of starch, 15 parts of magnesium stearate.Functions of removing chloasma capsule prepared by the present invention, instructions of taking is simple, and cure rate is high, controls recurrence rate after healing low, it is adaptable to various chloasma symptoms, and preparation method is simple, is adapted to large-scale industrial production.
Description
Technical field
Improve skin capsule, more particularly to a kind of functions of removing chloasma capsule and preparation method thereof the present invention relates to one kind.
Background technology
Chloasma is mainly in the women of women, the particularly gestational period, postpartum and oral contraceptive.Fash symmetry distribution in
Face, volume, two cheeks, bridge of the nose both sides, around lip, skin of chin, in referring to lid to coin size or in hand size, in irregular shape
Filbert or crineous sink spot, boundary is obvious or smudgy, can be fused into sheet.No conscious sympton, chronic process, Exposure to Sunlight
Postemphasis.A part after childbirth or after disabling contraceptive due to can slowly disappear.
The appearance of chloasma is most relevant with endocrine, relevant especially with the estrogen level of women, irregular menstruation, pregnant
It is pregnent, takes contraceptive or liver function is bad and chronic kidney disease is all likely to occur chloasma.In addition Exposure to Sunlight and mental element can also add
This disease of weight.The combination of inner and outside is wanted in the treatment of chloasma, first has to dispel the cause of disease, and strict sun-proof.Externally applied drug is commonly used for Kligman and matched somebody with somebody
Side：5% quinhydrones, 0.1% Tretinoin and 0.1% dexamethasone.There are some whitening cosmetics to contain ursin, dimension on the market
The whitening composition such as raw element C/E and its derivative, some Flavonoids and Polyphenols extract, niacinamide, external application also has necessarily
Effect, can use cooperatively.Above-mentioned therapeutic scheme can not usually remove root, easy recurrent exerbation, and with side effect.
Patent 201410814395.9 discloses a kind of enriching yin functions of removing chloasma oral liquid.Enriching yin functions of removing chloasma oral liquid raw material
Component include Chinese medicine prepared rhizome of rehmannia 14~16%, Chinese yam 15~17%, Poria cocos 10~12%, rhizoma alismatis 10~12%, golden cypress 9~
11%th, chrysanthemum 9~11%, moutan bark 5~7%, dogwood fruit 6~8%, the fruit of Chinese wolfberry 6~8%, dried orange peel 6~8%.The enriching yin is dispelled Huang
Foxiness oral liquid is using being made, and formula is reasonable, the effects such as with nourishing liver and kidney, nourishing yin and purging fire；It is mainly used to chloasma, symptoms include face
There is shallow or deep brown class etc..But, its taste is unpleasant, and patient is easily recurred after healing.
The content of the invention
It is an object of the invention to provide a kind of functions of removing chloasma capsule and preparation method thereof.
A kind of functions of removing chloasma capsule, includes the raw material of following parts by weight：100-200 parts of Salvia root P.E, Radix Angelicae Sinensis is extracted
100-150 parts of thing, 60-100 parts of Flos Rosae Rugosae extract, 50-80 parts of ginkgo biloba extract, 60-100 parts of collagen, grape pip is carried
Take 25-50 parts of thing, 20-35 parts of starch, 1-5 parts of magnesium stearate.
The extracting method of the Salvia root P.E is：Choose the medicinal material red sage root, clay into power, plus 3-5 times of weight 70% second
Alcohol solution refluxing extraction 1-3 times, merging filtrate is evaporated and is made.
The extracting method of the angelica extract is：Choose medicinal material Radix Angelicae Sinensis, clay into power, plus 3-5 times of weight 70% second
Alcohol solution refluxing extraction 1-3 times, merging filtrate is evaporated and is made.
The extracting method of the Flos Rosae Rugosae extract is：Choose new fresh-rose, grind pulp, plus 3-5 times of weight
70% ethanol water refluxing extraction 1-3 times, merging filtrate is evaporated and is made.
The extracting method of the grape seed extract is：Choose grape pip, clay into power, plus 3-5 times of weight 70% second
Alcohol solution refluxing extraction 1-3 times, merging filtrate is evaporated and is made.
The extracting method of the ginkgo biloba extract is：Choose medicinal material ginkgo leaf, clay into power, plus 3-5 times of weight 70%
Ethanol water refluxing extraction 1-3 times, merging filtrate is evaporated and is made.
Also include 20-50 parts of thin,tough silk moss extracts in the functions of removing chloasma capsule, extracting method is：Choose thin,tough silk moss, grinds
End, plus 3-5 times of weight 70% ethanol water refluxing extraction 1-3 times, merging filtrate is evaporated and is made.
The preparation method of above-mentioned functions of removing chloasma capsule, is carried out in accordance with the following steps：
(1) according to parts by weight, 20-35 parts of starch, 100-200 parts of Salvia root P.E, angelica extract 100-150 are weighed
Part, 60-100 parts of Flos Rosae Rugosae extract, 60-100 parts of collagen, 25-50 parts of grape seed extract, ginkgo biloba extract 50-80
Part is well mixed, and particle is made in dry granulation；
(2) 1-5 parts of magnesium stearate is added into the particle being made, is well mixed, particle to be filled is made；
(3) capsule is filled, every capsule fills 0.3-1g；
(4) polishing is sequentially passed through, screening (removes unqualified and defect ware), and finished product is made in inner packing, outer packing.
Compared with prior art, the present invention has the advantages that：Functions of removing chloasma capsule prepared by the present invention, the side of taking
Method is simple, and cure rate is high, controls recurrence rate after healing low, it is adaptable to various chloasma symptoms, it is not necessary to which external application coordinates, therapeutic scheme letter
Single, the preparation method of functions of removing chloasma capsule is simple, is adapted to large-scale industrial production.
Brief description of the drawings
Fig. 1 is technological process prepared by functions of removing chloasma capsule of the present invention.
Embodiment
Below in conjunction with the accompanying drawings, the embodiment to the present invention is described in detail, it is to be understood that the guarantor of the present invention
Shield scope is not limited by embodiment.
In following embodiments, the extracting method of the Salvia root P.E is：The medicinal material red sage root is chosen, is clayed into power, plus 3-5 times
70% ethanol water refluxing extraction of weight 1-3 times, merging filtrate is evaporated and is made.
The extracting method of the angelica extract is：Choose medicinal material Radix Angelicae Sinensis, clay into power, plus 3-5 times of weight 70% second
Alcohol solution refluxing extraction 1-3 times, merging filtrate is evaporated and is made.
The extracting method of the Flos Rosae Rugosae extract is：Choose new fresh-rose, grind pulp, plus 3-5 times of weight
70% ethanol water refluxing extraction 1-3 times, merging filtrate is evaporated and is made.
The extracting method of the grape seed extract is：Choose grape pip, clay into power, plus 3-5 times of weight 70% second
Alcohol solution refluxing extraction 1-3 times, merging filtrate is evaporated and is made.
The extracting method of the ginkgo biloba extract is：Choose medicinal material ginkgo leaf, clay into power, plus 3-5 times of weight 70%
Ethanol water refluxing extraction 1-3 times, merging filtrate is evaporated and is made.
The thin,tough silk moss extract extracting method is：Thin,tough silk moss is chosen, is clayed into power, plus 70% ethanol of 3-5 times of weight is water-soluble
Liquid refluxing extraction 1-3 times, merging filtrate is evaporated and is made.
Embodiment 1
A kind of functions of removing chloasma capsule, includes the raw material of following parts by weight：150 parts of Salvia root P.E, angelica extract 120
Part, 80 parts of Flos Rosae Rugosae extract, 80 parts of collagen, 30 parts of grape seed extract, 60 parts of ginkgo biloba extract, 30 parts of starch, firmly
3 parts of fatty acid magnesium.
The preparation method (as shown in Figure 1) of above-mentioned functions of removing chloasma capsule, is carried out in accordance with the following steps：
(1) according to parts by weight, 30 parts of starch is weighed, 150 parts of Salvia root P.E, 120 parts of angelica extract, rose carries
Take 80 parts of thing, 80 parts of collagen, 30 parts of grape seed extract, 60 parts of ginkgo biloba extract is well mixed, dry granulation is made
Grain；
(2) 3 parts of magnesium stearate is added into the particle being made, is well mixed, particle to be filled is made；
(3) capsule is filled, every capsule fills 0.5g；
(4) polishing is sequentially passed through, screening (removes unqualified and defect ware), and finished product is made in inner packing, outer packing.
Embodiment 2
A kind of functions of removing chloasma capsule, includes the raw material of following parts by weight：100 parts of Salvia root P.E, angelica extract 100
Part, 60 parts of Flos Rosae Rugosae extract, 60 parts of collagen, 25 parts of grape seed extract, 20 parts of starch, 50 parts of ginkgo biloba extract, firmly
1 part of fatty acid magnesium.
The preparation method of above-mentioned functions of removing chloasma capsule, is carried out in accordance with the following steps：
(1) according to parts by weight, 20 parts of starch is weighed, 100 parts of Salvia root P.E, 100 parts of angelica extract, rose carries
Take 60 parts of thing, 60 parts of collagen, 25 parts of grape seed extract, 50 parts of ginkgo biloba extract is well mixed, dry granulation is made
Grain；
(2) 1 part of magnesium stearate is added into the particle being made, is well mixed, particle to be filled is made；
(3) capsule is filled, every capsule fills 0.5g；
(4) polishing is sequentially passed through, screening (removes unqualified and defect ware), and finished product is made in inner packing, outer packing.
Embodiment 3
A kind of functions of removing chloasma capsule, includes the raw material of following parts by weight：200 parts of Salvia root P.E, angelica extract 150
Part, 100 parts of Flos Rosae Rugosae extract, 100 parts of collagen, 50 parts of grape seed extract, 80 parts of ginkgo biloba extract, 35 parts of starch,
5 parts of magnesium stearate.
The preparation method of above-mentioned functions of removing chloasma capsule, is carried out in accordance with the following steps：
(1) according to parts by weight, 35 parts of starch is weighed, 200 parts of Salvia root P.E, 150 parts of angelica extract, rose carries
100 parts of thing is taken, 100 parts of collagen, 50 parts of grape seed extract, 80 parts of ginkgo biloba extract is well mixed, dry granulation is made
Particle；
(2) 5 parts of magnesium stearate is added into the particle being made, is well mixed, particle to be filled is made；
(3) capsule is filled, every capsule fills 0.5g；
(4) polishing is sequentially passed through, screening (removes unqualified and defect ware), and finished product is made in inner packing, outer packing.
Embodiment 4
A kind of functions of removing chloasma capsule, includes the raw material of following parts by weight：150 parts of Salvia root P.E, angelica extract 120
Part, 80 parts of Flos Rosae Rugosae extract, 60 parts of ginkgo biloba extract, 30 parts of thin,tough silk moss extract, 80 parts of collagen, grape seed extract 30
Part, 30 parts of starch, 3 parts of magnesium stearate.
The preparation method (as shown in Figure 1) of above-mentioned functions of removing chloasma capsule, is carried out in accordance with the following steps：
(1) according to parts by weight, 30 parts of starch is weighed, 150 parts of Salvia root P.E, 120 parts of angelica extract, rose carries
80 parts of thing is taken, 60 parts of ginkgo biloba extract, 80 parts of collagen, 30 parts of thin,tough silk moss extract, 30 parts of grape seed extract, mixing is equal
Even, particle is made in dry granulation；
(2) 3 parts of magnesium stearate is added into the particle being made, is well mixed, particle to be filled is made；
(3) capsule is filled, every capsule fills 0.5g；
(4) polishing is sequentially passed through, screening (removes unqualified and defect ware), and finished product is made in inner packing, outer packing.
Embodiment 5
A kind of functions of removing chloasma capsule, includes the raw material of following parts by weight：150 parts of Salvia root P.E, angelica extract 120
Part, 80 parts of Flos Rosae Rugosae extract, 80 parts of collagen, 30 parts of grape seed extract, 30 parts of starch, 60 parts of ginkgo biloba extract, firmly
3 parts of fatty acid magnesium, 3 parts of lapis lazuli powder.
The preparation method (as shown in Figure 1) of above-mentioned functions of removing chloasma capsule, is carried out in accordance with the following steps：
(1) according to parts by weight, 30 parts of starch is weighed, 150 parts of Salvia root P.E, 120 parts of angelica extract, rose carries
Take 80 parts of thing, 60 parts of ginkgo biloba extract, 80 parts of collagen, 30 parts of grape seed extract is well mixed, dry granulation is made
Grain；
(2) 3 parts of magnesium stearate is added into the particle being made, 3 parts of lapis lazuli powder is well mixed, is made to be filled
Grain；
(3) capsule is filled, every capsule fills 0.5g；
(4) polishing is sequentially passed through, screening (removes unqualified and defect ware), and finished product is made in inner packing, outer packing.
Comparative example 1
A kind of functions of removing chloasma capsule, includes the raw material of following parts by weight：150 parts of Salvia root P.E, angelica extract 120
Part, 60 parts of ginkgo biloba extract, 80 parts of Flos Rosae Rugosae extract, 80 parts of collagen, 30 parts of starch, 3 parts of magnesium stearate.
The preparation method (as shown in Figure 1) of above-mentioned functions of removing chloasma capsule, is carried out in accordance with the following steps：
(1) according to parts by weight, 30 parts of starch is weighed, 150 parts of Salvia root P.E, 120 parts of angelica extract, rose carries
80 parts of thing is taken, 60 parts of ginkgo biloba extract, 80 parts of collagen is well mixed, particle is made in dry granulation；
(2) 3 parts of magnesium stearate is added into the particle being made, is well mixed, particle to be filled is made；
(3) capsule is filled, every capsule fills 0.5g；
(4) polishing is sequentially passed through, screening (removes unqualified and defect ware), and finished product is made in inner packing, outer packing.
Experimental example：
Every group of selection patient with chloasma 100, symptom is：Fash symmetry distribution in face, volume, two cheeks, bridge of the nose both sides,
Around lip, skin of chin, sink spot in lid is referred to coin size or in hand size, in irregular shape filbert or crineous,
Boundary is obvious or smudgy, can be fused into sheet.0.5g/, 2 times a day, daily 3, continuously takes 120 days, statistics is controlled
More rate, cures later six months, counts recurrence rate, and statistical result is shown in Table 1：
Table 1
As can be seen from Table 1, embodiment 1 only adds grape seed extract, cure rate less compared with comparative example 1
Decline, recurrence rate rises, it was demonstrated that grape seed extract has key effect, embodiment 1 and embodiment 4 for the treatment of chloasma
Compare, only embodiment more than 4 adds thin,tough silk moss extract, cure rate rises, recurrence rate declines, it was demonstrated that thin,tough silk moss extract for
The treatment of chloasma has key effect, and compared with Example 5, only embodiment more than 5 adds lapis lazuli powder to embodiment 1
End, cure rate rises, and recurrence rate declines, it was demonstrated that lapis lazuli has key effect for the treatment of chloasma.
Disclosed above is only the specific embodiment of the present invention, and still, the present invention is not limited to this, any this area
What technical staff can think change should all fall into protection scope of the present invention.
Claims (8)
1. a kind of functions of removing chloasma capsule, it is characterised in that include the raw material of following parts by weight：100-200 parts of Salvia root P.E,
100-150 parts of angelica extract, 60-100 parts of Flos Rosae Rugosae extract, 60-100 parts of collagen, grape seed extract 25-50
Part, 50-80 parts of ginkgo biloba extract, 20-35 parts of starch, 1-5 parts of magnesium stearate.
2. functions of removing chloasma capsule according to claim 1, it is characterised in that the extracting method of the Salvia root P.E is：
Choose the medicinal material red sage root, clay into power, plus 3-5 times of weight 70% ethanol water refluxing extraction 1-3 times, merging filtrate is evaporated
It is made.
3. functions of removing chloasma capsule according to claim 1, it is characterised in that the extracting method of the angelica extract is：
Choose medicinal material Radix Angelicae Sinensis, clay into power, plus 3-5 times of weight 70% ethanol water refluxing extraction 1-3 times, merging filtrate is evaporated
It is made.
4. functions of removing chloasma capsule according to claim 1, it is characterised in that the extracting method of the Flos Rosae Rugosae extract
For：Choose new fresh-rose, grind pulp, plus 3-5 times of weight 70% ethanol water refluxing extraction 1-3 time, merge and filter
Liquid, is evaporated and is made.
5. functions of removing chloasma capsule according to claim 1, it is characterised in that the extracting method of the grape seed extract
For：Choose grape pip, clay into power, plus 3-5 times of weight 70% ethanol water refluxing extraction 1-3 times, merging filtrate is evaporated
It is made.
6. functions of removing chloasma capsule according to claim 1, it is characterised in that also including 20-50 parts of thin,tough silk moss extracts, is extracted
Method is：Choose thin,tough silk moss, clay into power, plus 3-5 times of weight 70% ethanol water refluxing extraction 1-3 time, merging filtrate, steaming
It is drying into.
7. functions of removing chloasma capsule according to claim 1, it is characterised in that the extracting method of the ginkgo biloba extract is：
Choose medicinal material ginkgo leaf, clay into power, plus 3-5 times of weight 70% ethanol water refluxing extraction 1-3 time, merging filtrate, steaming
It is drying into.
8. the preparation method of functions of removing chloasma capsule according to claim 1, it is characterised in that carry out in accordance with the following steps：
(1) according to parts by weight, 20-35 parts of starch is weighed, 100-200 parts of Salvia root P.E, 100-150 parts of angelica extract,
60-100 parts of Flos Rosae Rugosae extract, 60-100 parts of collagen, 25-50 parts of grape seed extract, 50-80 parts of ginkgo biloba extract is mixed
Close uniform, particle is made in dry granulation；
(2) 1-5 parts of magnesium stearate is added into the particle being made, is well mixed, particle to be filled is made；
(3) capsule is filled, every capsule fills 0.3-1g；
(4) polishing is sequentially passed through, is screened, finished product is made in inner packing, outer packing.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710445026.0A CN107224572A (en) | 2017-06-14 | 2017-06-14 | A kind of functions of removing chloasma capsule and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710445026.0A CN107224572A (en) | 2017-06-14 | 2017-06-14 | A kind of functions of removing chloasma capsule and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107224572A true CN107224572A (en) | 2017-10-03 |
Family
ID=59934934
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710445026.0A Pending CN107224572A (en) | 2017-06-14 | 2017-06-14 | A kind of functions of removing chloasma capsule and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107224572A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2022063307A1 (en) * | 2020-09-28 | 2022-03-31 | 中国科学院上海营养与健康研究所 | Application of targeted tert in regulating skin and hair pigments |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104068404A (en) * | 2014-07-15 | 2014-10-01 | 南京中医药大学 | Health product with function of chloasma removal |
| CN105687522A (en) * | 2016-03-15 | 2016-06-22 | 双飞人制药股份有限公司 | Pharmaceutical composition with chloasma removing function and preparation method thereof |
-
2017
- 2017-06-14 CN CN201710445026.0A patent/CN107224572A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104068404A (en) * | 2014-07-15 | 2014-10-01 | 南京中医药大学 | Health product with function of chloasma removal |
| CN105687522A (en) * | 2016-03-15 | 2016-06-22 | 双飞人制药股份有限公司 | Pharmaceutical composition with chloasma removing function and preparation method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 徐振秋: "一种祛黄褐斑保健食品人体试食效果观察", 《食品与发酵科技》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2022063307A1 (en) * | 2020-09-28 | 2022-03-31 | 中国科学院上海营养与健康研究所 | Application of targeted tert in regulating skin and hair pigments |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103393599B (en) | Preparation method of traditional Chinese medicine fine powder | |
| CN105497246B (en) | Traditional Chinese medicine material for treating whelk and preparation method of traditional Chinese medicine | |
| CN105147847A (en) | Drug composition for benefiting qi and nourishing blood | |
| CN104739704A (en) | Traditional Chinese medicinal soup and preparation method thereof | |
| CN101623446A (en) | Chinese medicinal composition for treating alopecia and premature graying of hair | |
| CN107224572A (en) | A kind of functions of removing chloasma capsule and preparation method thereof | |
| CN102846879B (en) | Composition for depressing blood fat | |
| CN104435424A (en) | Medicine for treating male climacteric syndrome | |
| CN104398466A (en) | Formula of whitening, spot-removing, and nourishing facial-mask paste | |
| CN106334178A (en) | Alopecia-preventing and hair growth promoting liniment and preparation method thereof | |
| CN104688904A (en) | Method for treating insomnia | |
| CN101062347A (en) | Chinese traditional medicine formula good for heart and brain | |
| CN103725576A (en) | Traditional Chinese medicine liquor and preparation method thereof | |
| CN102366543A (en) | Chinese herbal medicine for treating blood deficiency, blood heat and blood dryness | |
| CN106109968A (en) | Rhizoma Gastrodiae, Radix Polygoni Multiflori Preparata pharmaceutical composition and preparation method thereof | |
| CN105770658A (en) | Traditional Chinese medicine preparation for treating oral disease | |
| CN105148047A (en) | Traditional Chinese medicine decoction for treating breast milk stoppage | |
| CN101822760A (en) | Anti-senile dementia traditional Chinese medicine composite preparation and preparation process thereof | |
| CN104069289A (en) | Freckle-removing and whitening capsule and preparation method thereof | |
| CN104056017A (en) | Traditional Chinese medicine composition for treating rheumatism and preparation method thereof | |
| CN1073875A (en) | A kind of special " Shanhaidan " and production method thereof | |
| CN101618132A (en) | Chinese medicinal herb for treating aplastic anemia | |
| CN106075104A (en) | Rhizoma Gastrodiae, Radix Polygoni Multiflori Preparata combined pharmaceutical composition and preparation method thereof | |
| CN106075103A (en) | Rhizoma Gastrodiae, Radix Polygoni Multiflori Preparata pharmaceutical composition and preparation technology thereof | |
| CN105079402A (en) | Traditional Chinese medicine preparation for treating postpartum facial melasma of females and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20171003 |