CN107213402A - A kind of yellow acne cream of ice - Google Patents
A kind of yellow acne cream of ice Download PDFInfo
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- CN107213402A CN107213402A CN201710531025.8A CN201710531025A CN107213402A CN 107213402 A CN107213402 A CN 107213402A CN 201710531025 A CN201710531025 A CN 201710531025A CN 107213402 A CN107213402 A CN 107213402A
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- parts
- acne cream
- stemona
- tuber
- pearl
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- 239000006071 cream Substances 0.000 title claims abstract description 39
- 208000002874 Acne Vulgaris Diseases 0.000 title claims abstract description 37
- 206010000496 acne Diseases 0.000 title claims abstract description 37
- DTGKSKDOIYIVQL-WEDXCCLWSA-N (+)-borneol Chemical compound C1C[C@@]2(C)[C@@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-WEDXCCLWSA-N 0.000 claims abstract description 32
- REPVLJRCJUVQFA-UHFFFAOYSA-N (-)-isopinocampheol Natural products C1C(O)C(C)C2C(C)(C)C1C2 REPVLJRCJUVQFA-UHFFFAOYSA-N 0.000 claims abstract description 32
- 229940116229 borneol Drugs 0.000 claims abstract description 32
- CKDOCTFBFTVPSN-UHFFFAOYSA-N borneol Natural products C1CC2(C)C(C)CC1C2(C)C CKDOCTFBFTVPSN-UHFFFAOYSA-N 0.000 claims abstract description 32
- DTGKSKDOIYIVQL-UHFFFAOYSA-N dl-isoborneol Natural products C1CC2(C)C(O)CC1C2(C)C DTGKSKDOIYIVQL-UHFFFAOYSA-N 0.000 claims abstract description 32
- 241001313857 Bletilla striata Species 0.000 claims abstract description 28
- 244000157790 Buglossoides arvense Species 0.000 claims abstract description 28
- 235000004256 Buglossoides arvense Nutrition 0.000 claims abstract description 28
- 241000218691 Cupressaceae Species 0.000 claims abstract description 28
- 241001671204 Stemona Species 0.000 claims abstract description 28
- 229910052602 gypsum Inorganic materials 0.000 claims abstract description 28
- 239000010440 gypsum Substances 0.000 claims abstract description 28
- 244000247747 Coptis groenlandica Species 0.000 claims abstract description 27
- 235000002991 Coptis groenlandica Nutrition 0.000 claims abstract description 27
- 244000246386 Mentha pulegium Species 0.000 claims abstract description 24
- 235000016257 Mentha pulegium Nutrition 0.000 claims abstract description 24
- 235000004357 Mentha x piperita Nutrition 0.000 claims abstract description 24
- 240000004980 Rheum officinale Species 0.000 claims abstract description 24
- 235000008081 Rheum officinale Nutrition 0.000 claims abstract description 24
- 235000001050 hortel pimenta Nutrition 0.000 claims abstract description 24
- 239000010495 camellia oil Substances 0.000 claims abstract description 22
- 238000003756 stirring Methods 0.000 claims abstract description 19
- 229940099259 vaseline Drugs 0.000 claims abstract description 18
- 238000002360 preparation method Methods 0.000 claims abstract description 14
- 239000002994 raw material Substances 0.000 claims abstract description 11
- 239000000203 mixture Substances 0.000 claims abstract description 9
- 238000000034 method Methods 0.000 claims description 13
- 230000008569 process Effects 0.000 claims description 10
- 244000131316 Panax pseudoginseng Species 0.000 claims description 2
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 claims description 2
- 235000003140 Panax quinquefolius Nutrition 0.000 claims description 2
- 235000008434 ginseng Nutrition 0.000 claims description 2
- 238000005303 weighing Methods 0.000 claims 1
- 208000014617 hemorrhoid Diseases 0.000 abstract description 27
- 208000016583 Anus disease Diseases 0.000 abstract description 8
- 206010002153 Anal fissure Diseases 0.000 abstract description 6
- 208000009531 Fissure in Ano Diseases 0.000 abstract description 6
- 230000036592 analgesia Effects 0.000 abstract description 4
- 230000003110 anti-inflammatory effect Effects 0.000 abstract description 3
- 230000000844 anti-bacterial effect Effects 0.000 abstract description 2
- 229940088710 antibiotic agent Drugs 0.000 abstract description 2
- 239000003908 antipruritic agent Substances 0.000 abstract description 2
- -1 heat after vaseline Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 description 10
- 208000032843 Hemorrhage Diseases 0.000 description 9
- 208000002193 Pain Diseases 0.000 description 9
- 208000034158 bleeding Diseases 0.000 description 9
- 230000000740 bleeding effect Effects 0.000 description 9
- 230000036407 pain Effects 0.000 description 9
- 239000008280 blood Substances 0.000 description 8
- 210000004369 blood Anatomy 0.000 description 8
- 240000002853 Nelumbo nucifera Species 0.000 description 7
- 235000006508 Nelumbo nucifera Nutrition 0.000 description 7
- 235000006510 Nelumbo pentapetala Nutrition 0.000 description 7
- 208000024891 symptom Diseases 0.000 description 6
- 206010048946 Anal abscess Diseases 0.000 description 5
- 208000004680 Rectal Fistula Diseases 0.000 description 5
- 206010002156 anal fistula Diseases 0.000 description 5
- 210000000436 anus Anatomy 0.000 description 5
- 229940079593 drug Drugs 0.000 description 5
- 230000000694 effects Effects 0.000 description 5
- 230000029663 wound healing Effects 0.000 description 5
- 201000004624 Dermatitis Diseases 0.000 description 4
- 230000000202 analgesic effect Effects 0.000 description 4
- 208000010668 atopic eczema Diseases 0.000 description 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 4
- 238000002156 mixing Methods 0.000 description 4
- 231100000614 poison Toxicity 0.000 description 4
- 230000001737 promoting effect Effects 0.000 description 4
- 201000010099 disease Diseases 0.000 description 3
- 238000005469 granulation Methods 0.000 description 3
- 230000003179 granulation Effects 0.000 description 3
- 206010061218 Inflammation Diseases 0.000 description 2
- 206010030113 Oedema Diseases 0.000 description 2
- 208000003251 Pruritus Diseases 0.000 description 2
- 240000004824 Trimezia steyermarkii Species 0.000 description 2
- 230000009471 action Effects 0.000 description 2
- 230000003213 activating effect Effects 0.000 description 2
- 230000017531 blood circulation Effects 0.000 description 2
- 230000013872 defecation Effects 0.000 description 2
- 239000009136 dragon's blood Substances 0.000 description 2
- 230000035876 healing Effects 0.000 description 2
- 208000035861 hematochezia Diseases 0.000 description 2
- 230000023597 hemostasis Effects 0.000 description 2
- 230000006872 improvement Effects 0.000 description 2
- 230000004054 inflammatory process Effects 0.000 description 2
- 230000017074 necrotic cell death Effects 0.000 description 2
- 239000002574 poison Substances 0.000 description 2
- 238000010926 purge Methods 0.000 description 2
- 201000009890 sinusitis Diseases 0.000 description 2
- 230000008961 swelling Effects 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 239000003440 toxic substance Substances 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 1
- 206010010774 Constipation Diseases 0.000 description 1
- 241000792859 Enema Species 0.000 description 1
- 208000004232 Enteritis Diseases 0.000 description 1
- 208000035965 Postoperative Complications Diseases 0.000 description 1
- 206010061926 Purulence Diseases 0.000 description 1
- 208000015815 Rectal disease Diseases 0.000 description 1
- 208000005392 Spasm Diseases 0.000 description 1
- 208000033809 Suppuration Diseases 0.000 description 1
- 208000007536 Thrombosis Diseases 0.000 description 1
- 206010052428 Wound Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 229940106766 ana-lex Drugs 0.000 description 1
- 210000002255 anal canal Anatomy 0.000 description 1
- 230000002785 anti-thrombosis Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 230000003467 diminishing effect Effects 0.000 description 1
- 238000002651 drug therapy Methods 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 239000007920 enema Substances 0.000 description 1
- 229940095399 enema Drugs 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 210000004347 intestinal mucosa Anatomy 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 235000013372 meat Nutrition 0.000 description 1
- 230000010534 mechanism of action Effects 0.000 description 1
- 230000000116 mitigating effect Effects 0.000 description 1
- 210000004877 mucosa Anatomy 0.000 description 1
- 210000004400 mucous membrane Anatomy 0.000 description 1
- 239000002674 ointment Substances 0.000 description 1
- 230000035699 permeability Effects 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 230000002980 postoperative effect Effects 0.000 description 1
- 210000000664 rectum Anatomy 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 238000009738 saturating Methods 0.000 description 1
- 210000005070 sphincter Anatomy 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 230000001732 thrombotic effect Effects 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 231100000765 toxin Toxicity 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/904—Stemonaceae (Stemona family), e.g. croomia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/618—Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/30—Boraginaceae (Borage family), e.g. comfrey, lungwort or forget-me-not
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/489—Sophora, e.g. necklacepod or mamani
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/534—Mentha (mint)
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/708—Rheum (rhubarb)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/718—Coptis (goldthread)
-
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/898—Orchidaceae (Orchid family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0031—Rectum, anus
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
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- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Biotechnology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Alternative & Traditional Medicine (AREA)
- Engineering & Computer Science (AREA)
- Marine Sciences & Fisheries (AREA)
- Zoology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Inorganic Chemistry (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicinal Preparation (AREA)
Abstract
The invention discloses a kind of yellow acne cream of ice and its preparation technology, the acne cream includes according to the raw material of parts by weight：30 120 parts of the coptis, 30 120 parts of golden cypress, 30 120 parts of rheum officinale, 10 50 parts of Resina Draconis, 10 50 parts of Asian puccoon, 30 120 parts of the tuber of stemona, 30 120 parts of kuh-seng, 30 120 parts of the bletilla striata, 10 50 parts of pearl, 100 300 parts of calcined gypsum, 30 90 parts of natural borneol, 20 80 parts of peppermint, 1,900 2100 parts of vaseline, 25 35 parts of tea oil.Each raw material is crushed respectively, cross 200 mesh sieves it is standby；Mix, heat after vaseline, tea oil are weighed, being cooled to 60 70 DEG C, adding the coptis, golden cypress, rheum officinale, Resina Draconis, Asian puccoon, the tuber of stemona, kuh-seng, the bletilla striata, calcined gypsum stirring, adding pearl, peppermint, natural borneol stirring, be down to normal temperature and produce.Contain antibacterials in the present invention, anti-inflammatory, detumescence, analgesia, antipruritic agent are evident in efficacy, it is adaptable to treat internal piles, external piles, mixed hemorrhoid, anal fissure etc..
Description
Technical field
It is specifically to contain borneol, the acne cream of rheum officinale and its preparation technology the present invention relates to pharmaceutical technology field.
Background technology
Hemorrhoid are most common anorectal diseases, and any age can all fall ill, but with age, the incidence of disease gradually increases
It is high.Hemorrhoid are divided into internal piles, external piles, mixed hemorrhoid by the difference of happening part.Have one in the junction of anal canal skin and rectal mucosa
The jagged visible line of bar is anal tube dentate line.More than dentate line for internal piles；It is external piles below dentate line, is coated to anus
Pipe mucous membrane；Have concurrently internal piles and external piles for mixed hemorrhoid.Hemorrhoid, which are mainly shown as, has blood in stool, the property having blood in stool can for it is painless, intermittent,
Blood after an action of the bowels, bled when just or toilet paper on band blood, constipation, drink or feed irritable food postemphasis, pure internal piles is without pain
Pain only falling inflation sense, can bleeding, be developed to prolapsus, pain just occurs in merging thrombosis during infection.
The major way for the treatment of hemorrhoid is divided into drug therapy and operative treatment, and general treatment method is that operation or transfusion are controlled
Treat.These treatment methods can make patient with complication over the course for the treatment of, and patient recovers slow, easily recurrence, it is impossible to timely solution
Except patient suffering, and radical cure is difficult, has had a strong impact on the work and life of patient.
The content of the invention
It is an object of the invention to provide a kind of yellow acne cream of ice and its preparation technology, to solve to carry in above-mentioned background technology
The problem of going out.
To achieve the above object, the present invention provides following technical scheme：
A kind of yellow acne cream of ice, includes according to the raw material of parts by weight：30-120 parts of the coptis, 30-120 parts of golden cypress, rheum officinale 30-120
Part, 10-50 parts of Resina Draconis, 10-50 parts of Asian puccoon, 30-120 parts of the tuber of stemona, 30-120 parts of kuh-seng, 30-120 parts of the bletilla striata, pearl 10-50
Part, 100-300 parts of calcined gypsum, 30-90 parts of natural borneol, 20-80 parts of peppermint, 1900-2100 parts of vaseline, 25-35 parts of tea oil.
It is used as further scheme of the invention：The yellow acne cream of a kind of ice, includes according to the raw material of parts by weight：The coptis
40-110 parts, it is 40-110 parts of golden cypress, 40-110 parts of rheum officinale, 20-40 parts of Resina Draconis, 20-40 parts of Asian puccoon, 40-110 parts of the tuber of stemona, bitter
40-110 parts of ginseng, 40-110 parts of the bletilla striata, 20-40 parts of pearl, 120-280 parts of calcined gypsum, 40-80 parts of natural borneol, peppermint 30-70
Part, 1950-2050 parts of vaseline, 28-32 parts of tea oil.
It is used as further scheme of the invention：2000 parts of the vaseline.
It is used as further scheme of the invention：30 parts of the tea oil.
Another object of the present invention is to provide a kind of preparation technology of the yellow acne cream of ice, comprises the following steps：
1）By the coptis, golden cypress, rheum officinale, Resina Draconis, Asian puccoon, the tuber of stemona, kuh-seng, the bletilla striata, pearl, calcined gypsum, natural borneol, peppermint point
200 mesh sieves, Fen Sui not be crossed, it is standby；
2）Mix, be heated to after 75-85 DEG C after vaseline, tea oil are weighed, be cooled to 60-70 DEG C, add the coptis, golden cypress,
Rheum officinale, Resina Draconis, Asian puccoon, the tuber of stemona, kuh-seng, the bletilla striata, calcined gypsum, at such a temperature after stir process 10-40min, add treasure
Pearl, peppermint, natural borneol, it is stirring while adding, produced until being down to normal temperature.
It is used as further scheme of the invention：Step 2）In, mix, be heated to after 80 DEG C after vaseline, tea oil are weighed,
It is cooled to 65 DEG C.
It is used as further scheme of the invention：Step 2）In, add the coptis, golden cypress, rheum officinale, Resina Draconis, Asian puccoon, the tuber of stemona,
Kuh-seng, the bletilla striata, calcined gypsum, at such a temperature stir process 15-30min.
It is used as further scheme of the invention：Step 2）In, mixing speed is 100-300r/min.
It is used as further scheme of the invention：Step 2）In, it is 20- to add pearl, peppermint, the total duration of natural borneol
90min。
Compared with prior art, the beneficial effects of the invention are as follows：
The coptis, golden cypress heat-clearing and damp-drying drug in the present invention, purging intense heat of detoxifying, two medicines, which are shared, slough is gone, and new meat must be raw；Rheum officinale purges heat
Poison, breaks stagnant, row extravasated blood；Resina Draconis promoting blood circulation to remove blood stasis, analgesic therapy hemostasis, expelling pus and promoting granulation；Asian puccoon, the tuber of stemona, kuh-seng cooling and activating blood, removing toxic substances
Promoting eruption；The bletilla striata, pearl, calcined gypsum are astringing to arrest bleeding, remove necrosis and promote granulation, promote wound healing；Natural borneol makes for assistant, with heat-clearing
Dissipate fire, activating blood circulation and reducing swelling, the work(of analgesic；Peppermint spasmolysis, promoting eruption.Above all medicines share, play altogether remove necrosis and promote granulation, clearing heat for detumescence, removing toxic substances
Hygroscopic, the work(of blood-activating and qi-promoting analgesic.
With reference to modern pharmacological research, antibacterials are contained in acne cream, anti-inflammatory, detumescence, analgesia, antipruritic agent, reduction are oozed
Go out medicine, reduce sphincterismus, anti-thrombosis drug, wound healing medicine.The present invention is applied to treatment internal piles, outer
Hemorrhoid, mixed hemorrhoid, anal fissure, perianal abscess, anal fistula, anal sinusitis, eczema of anus, nervi analex function, rectum inflammation etc..By for many years
Clinical research and application, it is mutually tied original pure manual paste manufacture process and modern biotechnology wall breaking technology etc. from genunie medicinal materials
Close, develop pure draft and the acne cream easily absorbed, because method is unique, the characteristics of evident in efficacy, firmly get many patients appreciation.
Clinical effectiveness of the present invention
1. the patient of expectant treatment：Inhibiting bacteria and diminishing inflammation is played to hemorrhoid complicated by anal fistula, is stopped blooding, intestinal mucosa is protected in analgesia, and sphincter is alleviated to anal fissure
Spasm.
2. the patient of preoperative external application：Repercusion analgesia is played to hemorrhoid disease, purulence toxin expelling is played to perianal abscess.Create operation
Face is small
3. the patient of postoperative external application：Reduce postoperative complications.Anti-inflammatory analgesic, hemostasis, rush are cured（Healing time shifts to an earlier date 1/3）.
Brief description of the drawings
Fig. 1 is the mechanism of action figure of acne cream of the present invention；
Fig. 2 is like product Comparison of therapeutic figure in clinical research in the embodiment of the present invention 6；
Fig. 3 is that acne cream symptom improvement figure of the present invention is used in the embodiment of the present invention 6.
Embodiment
Below in conjunction with the embodiment of the present invention, the technical scheme in the embodiment of the present invention is clearly and completely described,
Obviously, described embodiment is only a part of embodiment of the invention, rather than whole embodiments.Based in the present invention
Embodiment, the every other embodiment that those of ordinary skill in the art are obtained under the premise of creative work is not made, all
Belong to the scope of protection of the invention.
Embodiment 1
In the embodiment of the present invention, a kind of yellow acne cream of ice, including following raw material：Coptis 30g, golden cypress 30g, rheum officinale 30g, Resina Draconis
It is 10g, Asian puccoon 10g, tuber of stemona 30g, kuh-seng 30g, bletilla striata 30g, pearl 10g, calcined gypsum 100g, natural borneol 30g, peppermint 20g, all
Intellectual circle 1900g, tea oil 25g.
A kind of preparation technology of the yellow acne cream of ice, comprises the following steps：
1）By the coptis, golden cypress, rheum officinale, Resina Draconis, Asian puccoon, the tuber of stemona, kuh-seng, the bletilla striata, pearl, calcined gypsum, natural borneol, peppermint point
200 mesh sieves, Fen Sui not be crossed, it is standby.
2）Mix, be heated to after 75 DEG C after vaseline, tea oil are weighed, be cooled to 60 DEG C, add the coptis, golden cypress, big
Huang, Resina Draconis, Asian puccoon, the tuber of stemona, kuh-seng, the bletilla striata, calcined gypsum, at such a temperature after stir process 10min, add pearl, thin
Lotus, natural borneol, it is stirring while adding, produced until being down to normal temperature.
Embodiment 2
In the embodiment of the present invention, a kind of yellow acne cream of ice, including following raw material：Coptis 120g, golden cypress 120g, rheum officinale 120g, dragon
It is dragon's blood 50g, Asian puccoon 50g, tuber of stemona 120g, kuh-seng 120g, bletilla striata 120g, pearl 50g, calcined gypsum 300g, natural borneol 90g, thin
Lotus 80g, vaseline 2100g, tea oil 35g.
A kind of preparation technology of the yellow acne cream of ice, comprises the following steps：
1）By the coptis, golden cypress, rheum officinale, Resina Draconis, Asian puccoon, the tuber of stemona, kuh-seng, the bletilla striata, pearl, calcined gypsum, natural borneol, peppermint point
200 mesh sieves, Fen Sui not be crossed, it is standby.
2）Mix, be heated to after 85 DEG C after vaseline, tea oil are weighed, be cooled to 70 DEG C, add the coptis, golden cypress, big
Huang, Resina Draconis, Asian puccoon, the tuber of stemona, kuh-seng, the bletilla striata, calcined gypsum, at such a temperature after stir process 40min, add pearl, thin
Lotus, natural borneol, it is stirring while adding, produced until being down to normal temperature.
Embodiment 3
In the embodiment of the present invention, a kind of yellow acne cream of ice, including following raw material：Coptis 40g, golden cypress 40g, rheum officinale 40g, Resina Draconis
It is 20g, Asian puccoon 20g, tuber of stemona 40g, kuh-seng 40g, bletilla striata 40g, pearl 20g, calcined gypsum 120g, natural borneol 40g, peppermint 30g, all
Intellectual circle 1950g, tea oil 25g.
A kind of preparation technology of the yellow acne cream of ice, comprises the following steps：
1）By the coptis, golden cypress, rheum officinale, Resina Draconis, Asian puccoon, the tuber of stemona, kuh-seng, the bletilla striata, pearl, calcined gypsum, natural borneol, peppermint point
200 mesh sieves, Fen Sui not be crossed, it is standby.
2）Mix, be heated to after 78 DEG C after vaseline, tea oil are weighed, be cooled to 62 DEG C, add the coptis, golden cypress, big
Huang, Resina Draconis, Asian puccoon, the tuber of stemona, kuh-seng, the bletilla striata, calcined gypsum, at such a temperature after stir process 15min, add pearl, thin
Lotus, natural borneol, stirring while adding, mixing speed is 100r/min, adds pearl, peppermint, the total duration of natural borneol and is
20min, is produced until being down to normal temperature.
Embodiment 4
In the embodiment of the present invention, a kind of yellow acne cream of ice, including following raw material：Coptis 110g, golden cypress 110g, rheum officinale 110g, dragon
It is dragon's blood 40g, Asian puccoon 40g, tuber of stemona 110g, kuh-seng 110g, bletilla striata 110g, pearl 40g, calcined gypsum 280g, natural borneol 80g, thin
Lotus 70g, vaseline 2050g, tea oil 35g.
A kind of preparation technology of the yellow acne cream of ice, comprises the following steps：
1）By the coptis, golden cypress, rheum officinale, Resina Draconis, Asian puccoon, the tuber of stemona, kuh-seng, the bletilla striata, pearl, calcined gypsum, natural borneol, peppermint point
200 mesh sieves, Fen Sui not be crossed, it is standby.
2）Mix, be heated to after 82 DEG C after vaseline, tea oil are weighed, be cooled to 68 DEG C, add the coptis, golden cypress, big
Huang, Resina Draconis, Asian puccoon, the tuber of stemona, kuh-seng, the bletilla striata, calcined gypsum, at such a temperature after stir process 30min, add pearl, thin
Lotus, natural borneol, stirring while adding, mixing speed is 300r/min, adds pearl, peppermint, the total duration of natural borneol and is
90min, is produced until being down to normal temperature.
Embodiment 5
In the embodiment of the present invention, a kind of yellow acne cream of ice, including following raw material：Coptis 80g, golden cypress 70g, rheum officinale 90g, Resina Draconis
It is 30g, Asian puccoon 30g, tuber of stemona 60g, kuh-seng 70g, bletilla striata 50g, pearl 30g, calcined gypsum 200g, natural borneol 60g, peppermint 50g, all
Intellectual circle 2000g, tea oil 30g.
A kind of preparation technology of the yellow acne cream of ice, comprises the following steps：
1）By the coptis, golden cypress, rheum officinale, Resina Draconis, Asian puccoon, the tuber of stemona, kuh-seng, the bletilla striata, pearl, calcined gypsum, natural borneol, peppermint point
200 mesh sieves, Fen Sui not be crossed, it is standby.
2）Mix, be heated to after 80 DEG C after vaseline, tea oil are weighed, be cooled to 65 DEG C, add the coptis, golden cypress, big
Huang, Resina Draconis, Asian puccoon, the tuber of stemona, kuh-seng, the bletilla striata, calcined gypsum, at such a temperature after stir process 20min, add pearl, thin
Lotus, natural borneol, stirring while adding, mixing speed is 100-300r/min, adds pearl, peppermint, the total duration of natural borneol
For 50min, produced until being down to normal temperature.
The clinical test of embodiment 6
120 patients of this research observation are 2014 to 2016 hemorrhoid, anal fissure, wherein anal fistula outpatients, male patient
60, female patient 60.Treatment group 60 and control group 60 are randomly divided into, two groups in age, sex, the course of disease, operation model
Enclose, surface of a wound size, have homogeneity in terms of the symptom of patient, sign before medication, two groups of cases have comparativity.Treatment group
Treated with the acne cream of the embodiment of the present invention 5.Control group is treated with certain horse board ointment.
Treatment standard
It is effective：Without bleeding, oozing of blood, pain substantially mitigates, and wound healing time substantially shortens；Effectively：Without bleeding, oozing of blood, pain
Mitigate, wound healing time shortens；It is invalid：A small amount of bleeding or a small amount of oozing of blood, pain is without mitigation, and wound healing time is without obvious contracting
It is short.
Treatment results are shown in Table 1.
Table 1
| Group | Case（Example） | It is effective（Example） | Effectively（Example） | It is invalid（Example） | Total effective rate（%） |
| Control group | 60 | 16 | 34 | 10 | 83.33 |
| Treatment group | 60 | 38 | 20 | 2 | 96.67 |
From table 1 it follows that acne cream of the present invention there can be significant curative effect to anal fistula, and substantially contracted in Clinical practice
Short healing time.
Like product Comparison of therapeutic figure is as shown in Figure 2 in clinical research of the present invention., will be corresponding from clinical research comparison diagram
More careful point of disease of anus list, more can accurately understand acne cream in each disease of anus Clinical practice
Advantage.Especially in perianal abscess, the effect of the saturating poison of its apocenosis is more notable；In terms of eczema of anus, certain horse board is that oiliness is soft
Its gas permeability of cream is poor, and certain aqueous cream, and easy Cheng Shui ripples, and causes affected part to smear rear generation eczema of long duration.
Symptom of the present invention improves：Curative effect to improvement bleeding, pain, oedema, breach, five sings and symptomses of itch is as follows
Shown in Fig. 3.As a result show, acne cream of the present invention is treated to improving the big sings and symptoms of bleeding, pain, oedema, breach, itch etc. five
Effect is notable.
Clinical research conclusion：Acne cream of the present invention is to hemorrhoid, anal fissure, anal fistula, perianal abscess, eczema of anus, anal sinusitis, straight
Enteritis has significant curative effect, can release or be obviously improved related symptoms caused by disease.
Model case：
Case 1：Chen, 58 years old, with hemorrhoid for many years, is diagnosed as the second phase, haemorrhoids is larger, can deviate from during stool outside anus, after an action of the bowels certainly
Row is also received, with bleeding when just.Smear 2 times daily, get better within 5 days and turn, no longer bled after 12 days, and no longer deviate from, be discontinued half a year
Do not recur.
Case 2；Wu, female 33 years old, has given birth to child, thrombotic hemorrhoid and Canton phenomenon, hurt like hell occurs, it is impossible to just
Normal defecation need to rely on enema, smear this medicine 7 days, and thrombosed hemorrhoid is eliminated, and Canton phenomenon substantially softens, can voluntarily defecation, after 1 year
Pay a return visit, no recurrence.
Case 3:Lee, man, 37 years old, perianal abscess was fallen ill 3 days, swelling and ache to sit down, and smears medicine of the present invention one day 3
Secondary, fester is discharged after 1 day, detumescence；Fester has been clapped substantially after 10 days, and vent gradually heals, and is healed after 15 days, is paid a return visit after 3 years,
Without recurrence.
Case 4；Zhang, man, 45 years old, is diagnosed as anal fissure, falls ill repeatedly half a year, dyschizia, with tear sense, companion when just
Bleed, smear this medicine 2 times a day, stool is eased after 1 day, pain mitigates, it is clinical not after bleeding, 7 days after 3 days
Symptom disappears, and is paid a return visit after 1 year, there is recurrence 1 time, is to obtain improving again not occurring after smearing.
It is obvious to a person skilled in the art that the invention is not restricted to the details of above-mentioned one exemplary embodiment, Er Qie
In the case of without departing substantially from spirit or essential attributes of the invention, the present invention can be realized in other specific forms.Therefore, no matter
From the point of view of which point, embodiment all should be regarded as exemplary, and be nonrestrictive, the scope of the present invention is by appended power
Profit is required rather than described above is limited, it is intended that all in the implication and scope of the equivalency of claim by falling
Change is included in the present invention.
Moreover, it will be appreciated that although the present specification is described in terms of embodiments, not each embodiment is only wrapped
Containing an independent technical scheme, this narrating mode of specification is only that for clarity, those skilled in the art should
Using specification as an entirety, the technical solutions in the various embodiments may also be suitably combined, forms those skilled in the art
It may be appreciated other embodiment.
Claims (9)
1. the yellow acne cream of a kind of ice, it is characterised in that include according to the raw material of parts by weight：30-120 parts of the coptis, golden cypress 30-120
Part, 30-120 parts of rheum officinale, 10-50 parts of Resina Draconis, 10-50 parts of Asian puccoon, 30-120 parts of the tuber of stemona, 30-120 parts of kuh-seng, bletilla striata 30-
120 parts, 10-50 parts of pearl, 100-300 parts of calcined gypsum, 30-90 parts of natural borneol, 20-80 parts of peppermint, vaseline 1900-2100
Part, 25-35 parts of tea oil.
2. the yellow acne cream of a kind of ice according to claim 1, it is characterised in that include according to the raw material of parts by weight：The coptis
40-110 parts, it is 40-110 parts of golden cypress, 40-110 parts of rheum officinale, 20-40 parts of Resina Draconis, 20-40 parts of Asian puccoon, 40-110 parts of the tuber of stemona, bitter
40-110 parts of ginseng, 40-110 parts of the bletilla striata, 20-40 parts of pearl, 120-280 parts of calcined gypsum, 40-80 parts of natural borneol, peppermint 30-70
Part, 1950-2050 parts of vaseline, 28-32 parts of tea oil.
3. a kind of yellow acne cream of ice according to claim 1 or 2, it is characterised in that 2000 parts of the vaseline.
4. a kind of yellow acne cream of ice according to claim 1 or 2, it is characterised in that 30 parts of the tea oil.
5. according to a kind of preparation technology of the yellow acne cream of any described ice of claim 1-4, it is characterised in that including following step
Suddenly：
1）By the coptis, golden cypress, rheum officinale, Resina Draconis, Asian puccoon, the tuber of stemona, kuh-seng, the bletilla striata, pearl, calcined gypsum, natural borneol, peppermint point
200 mesh sieves, Fen Sui not be crossed, it is standby；
2）Mix, be heated to after 75-85 DEG C after vaseline, tea oil are weighed, be cooled to 60-70 DEG C, add the coptis, golden cypress,
Rheum officinale, Resina Draconis, Asian puccoon, the tuber of stemona, kuh-seng, the bletilla striata, calcined gypsum, at such a temperature after stir process 10-40min, add treasure
Pearl, peppermint, natural borneol, it is stirring while adding, produced until being down to normal temperature.
6. a kind of preparation technology of the yellow acne cream of ice according to claim 5, it is characterised in that step 2）In, by all scholars
Woods, tea oil are mixed after weighing, and are heated to after 80 DEG C, are cooled to 65 DEG C.
7. a kind of preparation technology of the yellow acne cream of ice according to claim 5, it is characterised in that step 2）In, add yellow
Company, golden cypress, rheum officinale, Resina Draconis, Asian puccoon, the tuber of stemona, kuh-seng, the bletilla striata, calcined gypsum, at such a temperature stir process 15-30min.
8. a kind of preparation technology of the yellow acne cream of ice according to claim 5, it is characterised in that step 2）In, stirring speed
Spend for 100-300r/min.
9. a kind of preparation technology of the yellow acne cream of ice according to claim 5, it is characterised in that step 2）In, add precious
Pearl, peppermint, the total duration of natural borneol are 20-90min.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111481628A (en) * | 2019-01-28 | 2020-08-04 | 四川省中医药科学院中医研究所 | External-use medicine composition and preparation method and application thereof |
| CN111759893A (en) * | 2020-07-27 | 2020-10-13 | 林代富 | Anal soothing soft ointment and preparation method thereof |
| CN113546158A (en) * | 2020-11-27 | 2021-10-26 | 林炜超 | Wound care ointment and preparation process thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070098669A1 (en) * | 2005-10-31 | 2007-05-03 | Ross Rosen | Herbal skin formulation |
| CN105055753A (en) * | 2015-09-06 | 2015-11-18 | 黄志良 | Hemorrhoid ointment and preparation process thereof |
| CN106109948A (en) * | 2016-08-29 | 2016-11-16 | 李佛根 | A kind of anal fistula cream and preparation method |
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2017
- 2017-07-03 CN CN201710531025.8A patent/CN107213402B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070098669A1 (en) * | 2005-10-31 | 2007-05-03 | Ross Rosen | Herbal skin formulation |
| CN105055753A (en) * | 2015-09-06 | 2015-11-18 | 黄志良 | Hemorrhoid ointment and preparation process thereof |
| CN106109948A (en) * | 2016-08-29 | 2016-11-16 | 李佛根 | A kind of anal fistula cream and preparation method |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111481628A (en) * | 2019-01-28 | 2020-08-04 | 四川省中医药科学院中医研究所 | External-use medicine composition and preparation method and application thereof |
| CN111759893A (en) * | 2020-07-27 | 2020-10-13 | 林代富 | Anal soothing soft ointment and preparation method thereof |
| CN113546158A (en) * | 2020-11-27 | 2021-10-26 | 林炜超 | Wound care ointment and preparation process thereof |
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| CN107213402B (en) | 2020-07-03 |
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