CN107213393A - 一种治疗痛风性关节炎的中药组合物 - Google Patents
一种治疗痛风性关节炎的中药组合物 Download PDFInfo
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Abstract
本发明公开了一种治疗痛风性关节炎的中药组合物,该中药组合物包括以重量份计的如下组分:土茯苓5‑10份、威灵仙1‑2份、川乌1‑2份、萆薢1‑4份、穿山龙1‑4份、百合1‑2份、怀牛膝1‑3份、苍术1‑3份、黄柏1‑3份、虎杖1‑3份、车前草1‑5份、苡仁10‑16份、独活1‑2份、海藻2‑2.4份、蒲公英2‑3份、山楂1‑2份、泽泻1‑2份、大黄0.5‑2份、核桃1‑2份、天麻1‑3份。本发明提供的中药组合物对痛风性关节炎具有明显的药理作用,总体来说本发明提供的中药组合物治疗痛风性关节炎疗程短、治愈率高、治疗效果显著的优点,且治疗费用低。
Description
技术领域
本发明涉及一种中药,尤其是涉及一种用于治疗痛风性关节炎的中药组合物。
背景技术
痛风性关节炎是由于尿酸盐沉积在关节囊、滑囊、软骨、骨质和其他组织中引起的病损及炎症反应,其多有遗传因素,好发于40岁以上男性,多见于第一趾指关节,也可发生于其他较大关节,尤其是膝部、踝部与足部关节,主要表现为关节组织周围明显肿胀、发热、发红和疼痛,通常分为急性关节炎期、间歇期、慢性关节炎期三个临床阶段。尿酸是嘌呤代谢的最终产物,长期嘌呤代谢障碍、血尿酸增高会引起痛风,血液中的尿酸长期处于饱和浓度时,尿酸盐会以晶体形式积存于软组织中,最终导致痛风性关节炎。治疗痛风性关节炎常用药有非甾类抗炎药、秋水仙碱、糖皮质激素以及苯溴马隆等,抑制尿酸生产及促进尿酸代谢的药物。这些药物都需要长期服用,存在一定的毒副作用,部分患者用药过程中甚至会引起痛风。本发明的目的是为了克服上述西药的毒副作用,一种用于治疗痛风性关节炎的中药组合物。
发明内容
本发明的目的是提供一种治疗痛风性关节炎的中药组合物,以改善现有治疗高血脂症药物大多为西药,毒副作用强,疗程长、成本高、效果不理想等技术问题。
为了解决上述技术问题,本发明采用的技术方案是:一种治疗痛风性关节炎的中药组合物,包括以重量份计的如下组分:土茯苓5-10份、 威灵仙1-2份、川乌1-2份、 萆薢1-4份、穿山龙1-4份、百合1-2份、怀牛膝1-3份、 苍术1-3份、 黄柏1-3份、虎杖1-3份、车前草1-5份、苡仁10-16份、独活1-2份、海藻2-2.4份、蒲公英2-3份、山楂1-2份、泽泻1-2份、大黄0.5-2份、核桃1-2份、天麻1-3份。
作为优选,所述治疗痛风性关节炎的中药组合物,包括以重量份计的如下组分:土茯苓5份、 威灵仙2份、川乌2份、 萆薢1份、穿山龙1份、百合1份、怀牛膝1份、 苍术1份、 黄柏1份、虎杖1份、车前草1份、苡仁10份、独活1份、海藻2份、蒲公英2份、山楂1份、泽泻1份、大黄0.5份、核桃1份、天麻1份。
该药物制备时,将上述各组分按重量份称量后,磨成细粉,过筛并加水煎煮三次,直接饮用。
本发明的组分中,土茯苓味甘、淡,性平,归肝、胃经,有解毒,除湿,通利关节之功效,主要用于肢体拘挛,筋骨疼痛,湿热淋浊,带下,痈肿等。威灵仙味辛、咸,性温,有祛风湿,通经络的作用,用于风湿痹痛,肢体麻木,筋脉拘挛,屈伸不利。川乌味辛、苦,性热,归心、肝、肾、脾经,具有祛风除湿,温经止痛的功效,用于风寒湿痹,关节疼痛,心腹冷痛,寒疝作痛及麻醉止痛。萆薢味苦,平,归肾、胃经,有利湿去浊,祛风除痹的功效,用于膏淋、风湿痹痛、关节不利、腰膝疼痛等症。穿山龙味甘、苦,性温,归肝,肾、肺经,有祛风除湿,舒筋通络,活血止痛,止咳平喘的作用。百合拥有治疗痛风的特效成分,可抑制白细胞的趋化作用,改善关节炎症状,还能利尿,促进尿酸排泄。怀牛膝所含的脱皮甾酮能改善肝功能,降低血浆胆固醇,有增强细胞活性的作用,具有抗炎的效果,是知名的活血散瘀、祛湿利尿的药物。苍术味辛、苦,性温,归脾、胃、肝经,是利水渗湿药物,能利于尿酸代谢。黄柏味苦,性寒,是清热燥湿代表中药,能明显降低患者体内血清尿酸水平,具有很好的抗痛风效果。虎杖味微苦,性微寒,有利湿退黄、清热解毒、散瘀止痛的功效,它有祛风利湿、散瘀定痛的功效,用于关节痹痛、臃肿疼痛。车前草归肝、肾、膀胱经,用于水肿尿少、热淋涩痛、痈肿疮毒等症。苡仁含苡仁脂,具有丰富的蛋白质、维生素等,可帮助降低体内的胆固醇和三酸甘油脂,预防心脑血管疾病,降低三高,促进新陈代谢,有利尿消肿的功效。独活味辛、苦,性微温,归肾、膀胱经,主要功效为祛风除湿、痛痹止痛。海藻富含烟碱酸,在治疗关节炎方面有很好的效果,能促进消化,李煜尿酸及其他有害物质的代谢,且富含维生素,可预防嘌呤代谢障碍,能一直和改善高血脂症状,利于改善患者的身体状况。蒲公英其性苦、甘、寒,归肝、胃经,具有清热解毒利湿功效,与苡仁配合,能够很好的降尿酸,治疗痛风。山楂具有消积化滞、活血化瘀的功效,山楂还能扩张血管和降压,调节血脂和胆固醇。泽泻味甘、淡,性寒,归肾、膀胱经,水肿胀满,泄泻尿少,痰饮眩晕,热淋涩痛,高脂血症,利于尿酸代谢。大黄具有攻积滞、清湿热、泻火、凉血、祛瘀等功效,用于实热便秘、积滞腹痛、痈肿疔疮等症。核桃味甘、性温,入肾、肺、大肠经,苦泄散瘀,入肝经血分,有较强的活血调经、祛瘀生新之功,适于血分瘀滞较重者。天麻性味甘、平,入肝经,是活血化瘀的良药,对改善痛风症状具有很好的疗效。
该治疗痛风性关节炎的中药组合物,合理配伍中药药物成分,其中不仅具有缓解疼痛、活血化瘀的药物,还有利于血液尿酸代谢,防止尿酸积累的成分,部分碱性药食同源组分,能避免摄入大量尿酸,改善心脑血管弹性,抑制痛风的发生。各组分的合理的配伍,能最大化的发挥各组分的效果,治疗效果很好,能缩短治疗周期,提高治疗效果,减轻病人身体负担和经济压力,因此本发明具有很好的经济效益和社会效益。
具体实施方式
下面将结合具体实施例,对本发明的技术方案进行清楚、完整地描述,显然,所描述的实施例仅仅是本发明一部分实施例,而不是全部的实施例。基于本发明中的实施例,本领域普通技术人员在没有做出创造性劳动前提下所获得的所有其他实施例,都属于本发明保护的范围。
实施例1:该治疗痛风性关节炎的中药组合物,包括以重量份计的如下组分:土茯苓5份、 威灵仙1份、川乌1份、 萆薢1份、穿山龙1份、百合1份、怀牛膝1份、 苍术1份、 黄柏1份、虎杖1份、车前草1份、苡仁10份、独活1份、海藻2份、蒲公英2份、山楂1份、泽泻1份、大黄0.5份、核桃1份、天麻1份。
实施例2:该治疗痛风性关节炎的中药组合物,包括以重量份计的如下组分:土茯苓5份、 威灵仙2份、川乌2份、 萆薢1份、穿山龙1份、百合1份、怀牛膝1份、 苍术1份、 黄柏1份、虎杖1份、车前草1份、苡仁10份、独活1份、海藻2份、蒲公英2份、山楂1份、泽泻1份、大黄0.5份、核桃1份、天麻1份。
实施例3:该治疗痛风性关节炎的中药组合物,包括以重量份计的如下组分:土茯苓10份、 威灵仙2份、川乌2份、 萆薢4份、穿山龙4份、百合2份、怀牛膝3份、 苍术3份、 黄柏3份、虎杖3份、车前草5份、苡仁16份、独活2份、海藻2.4份、蒲公英3份、山楂2份、泽泻2份、大黄2份、核桃2份、天麻3份。
治疗痛风性关节炎的中药组合物的制备方法为:的组分称量准确后,加水三次,三次加水的重量与中药的重量比为9:1、9:1、7:1煎煮成汤剂,直接饮用,每日服用三次,三个月为一个疗程,患者需节制饮食,忌烟酒,少吃海鲜、火锅等高嘌呤食物,多饮水,避免影响疗效。
选用本发明技术方案制备的药物进行疗效验证,选取某县人民医院60名痛风性关节炎的患者进行验证,患者年龄46-70岁,分为两组,每组30人。分别服用实施例2制备的药物和安慰剂,一天服用三次,连续用药三个月。验证结果如下:
区分 | 实施例2组 | 安慰剂对照组 |
总有效率 | 93% | 30% |
通过以上治疗结果可以发现,该治疗痛风性关节炎的中药组合物能很好的改善患者体内尿酸沉积、血液尿酸过高的现象,缓解疼痛,利尿消肿,加快尿酸代谢,预防和改善痛风及痛风性关节炎的发生几率。
最后,应当指出,以上具体实施方式仅是本发明较有代表性的例子。显然,本发明不限于上述具体实施方式,还可以有许多变形。凡是依据本发明的技术实质对以上具体实施方式所作的任何简单修改、等同变化与修饰,均应认为属于本发明的保护范围。
Claims (2)
1.一种治疗痛风性关节炎的中药组合物,其特征是该中药组合物包括以重量份计的如下组分:土茯苓5-10份、 威灵仙1-2份、川乌1-2份、 萆薢1-4份、穿山龙1-4份、百合1-2份、怀牛膝1-3份、 苍术1-3份、 黄柏1-3份、虎杖1-3份、车前草1-5份、苡仁10-16份、独活1-2份、海藻2-2.4份、蒲公英2-3份、山楂1-2份、泽泻1-2份、大黄0.5-2份、核桃1-2份、天麻1-3份。
2. 根据权利要求1所述的治疗痛风性关节炎的中药组合物,其特征是该中药组合物包括以重量份计的如下组分:土茯苓5份、 威灵仙2份、川乌2份、 萆薢1份、穿山龙1份、百合1份、怀牛膝1份、 苍术1份、 黄柏1份、虎杖1份、车前草1份、苡仁10份、独活1份、海藻2份、蒲公英2份、山楂1份、泽泻1份、大黄0.5份、核桃1份、天麻1份。
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