CN107198590A - Rat test platform and rat test platform application method - Google Patents
Rat test platform and rat test platform application method Download PDFInfo
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- CN107198590A CN107198590A CN201710344274.6A CN201710344274A CN107198590A CN 107198590 A CN107198590 A CN 107198590A CN 201710344274 A CN201710344274 A CN 201710344274A CN 107198590 A CN107198590 A CN 107198590A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D3/00—Appliances for supporting or fettering animals for operative purposes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D1/00—Surgical instruments for veterinary use
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D3/00—Appliances for supporting or fettering animals for operative purposes
- A61D2003/003—Appliances for supporting or fettering animals for operative purposes with head or neck restraining means
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D3/00—Appliances for supporting or fettering animals for operative purposes
- A61D2003/006—Appliances for supporting or fettering animals for operative purposes with leg or foot restraining means
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Abstract
The invention discloses a kind of rat test platform and rat test platform application method, the wherein rat test platform includes operating platform and is fixedly connected on multiple supporting legs of operating platform bottom；A head fixation kit, four slip foot fixation kits and thermostatically-controlled equipment and LED illumination lamp are additionally provided with operating platform；What head fixation kit can be consolidated is fixed rat head and is accurately positioned, and four are slided the four limbs that foot fixation kit is respectively used to fix rat；Coated with electric blanket to keep rat temperature constant on operating platform, and it is connected to form feedback regulation electric blanket temperature with rat anus temperature digital clinical thermometer.Cold light source LED illumination device is set in front of platform, is easy to visual area to observe.Rat test platform and rat test platform application method that the present invention is provided, it carries out electrode stimulating model experiment for rat and provides significant booster action.
Description
Technical field
The present invention relates to medic laboratory technology field, more particularly to a kind of rat test platform and rat test platform user
Method.
Background technology
It is well known that rat is one of more satisfactory and conventional experimental animal in biology, medical research and teaching.
Meanwhile, antimigraine is clinically common multiple diseases, is mainly shown as side or bilateral head recurrent exerbation
Throbbing pain, can be with Nausea and vomiting, regarding the nervous symptoms such as thing is abnormal.Then occur in that and come using electrode stimulating model
Carry out the research methods of antimigraine simulated experiment.
In electrode stimulating animal model some aids or auxiliary operation are needed to use during use (for example：
Mastoid operation dilator), (for example：How the four limbs of in experiment rat are fixed) etc.；Therefore, experimentation is set up in whole model
In, it is necessary to using substantial amounts of aid and other support staff could complete complexity operating procedure.
Thus, also no one kind can concentrate a variety of aids and auxiliary in current electrode stimulating animal model
Function, and is especially particularly adapted to the testing stand of electrode stimulating model experiment.
The content of the invention
It is an object of the invention to provide a kind of rat test platform and rat test platform application method, to solve above-mentioned ask
Topic.
In order to achieve the above object, the technical proposal of the invention is realized in this way：
The invention provides a kind of rat test platform, including operating platform and it is fixedly connected on the operating platform bottom
Multiple supporting legs；
A head fixation kit, four slip foot fixation kits and constant temperature control are additionally provided with the operating platform
Device and cold light source LED illumination lamp processed；The head fixation kit is used to rat head is fixed and is accurately positioned；Described in four
Slide the four limbs that foot fixation kit is respectively used to fix the rat, and the slip foot fixation kit and the rat
Four limbs are corresponded；The thermostatically-controlled equipment is used for the body temperature for controlling the rat；The cold light source LED illumination lamp is used to carry
For lighting source；
In four slip foot fixation kits, the slip foot fixation kit arranged distribution is in the operation two-by-two
The both sides of the axis of platform；The slip foot fixation kit is slidably matched along the operating platform surface；It is each described
Slide foot fixation kit and be all correspondingly arranged on two rows perforation, and two rows perforation is arranged separately on the slip foot fixation kit
Both sides operating platform surface on；It is supporting between the corresponding perforation of two rows to be provided with band rope；
Any one limb of the rat is once fixed by the slip foot fixation kit formation, and passes through two rows
Band rope in the corresponding perforation forms secondary fixation.
It is preferred that, can embodiment as one kind；The slip foot fixation kit specifically include slideway, be arranged on it is described
Sliding block on slideway；And it is fixedly connected with geometrical clamp on the sliding block；The relatively described slideway of the sliding block is slidably matched.
It is preferred that, can embodiment as one kind；The geometrical clamp specifically includes the clip of two c-type shapes, and two C
The clip of type shape is oppositely arranged, and formation is snapped fit attachment.
It is preferred that, can embodiment as one kind；The thermostatically-controlled equipment specifically includes electric blanket, body temperature screen and big
Mouse anus temperature digital clinical thermometer；The rat anus temperature digital clinical thermometer is electrically connected with the electric blanket and the body temperature screen respectively
Connect.It should be noted that rat anus temperature digital clinical thermometer can measure the body temperature of rat in real time, and pass through connected body temperature
Screen carries out body temperature and shown；The formation feedback regulation of connected electric blanket can also be passed through simultaneously；For example：The body of current rat
When temperature is too low, it can control to start the operation of electric blanket heated in real-time temperature；It is flat that above-mentioned electric blanket is laid on the operation
On platform.
It is preferred that, can embodiment as one kind；The head fixation kit specifically includes tooth fixed mechanism and two
Ear bar；Wherein, the tooth fixed mechanism is arranged on the front end of the axis of the operating platform, and two ear bars are arranged on
The both sides of the axis of the operating platform；The tooth fixed mechanism is used for the tooth for fixing the rat；Two ears
The external auditory meatus that bar inserts the rat respectively is used to fix the rat both sides.
It is preferred that, can embodiment as one kind；It is additionally provided with column, the column and is provided with the operating platform
Three-dimensional manipulating arm；Wherein, the three-dimensional manipulating arm specifically includes X-axis operation travelling arm, Y-axis operation travelling arm and Z axis operation and slided
Swing arm；The three-dimensional manipulating arm is used for by X-axis, Y-axis, three direction activities of Z axis to skull position hole to be drilled or rat head
Different brain region be accurately positioned.
It is preferred that, can embodiment as one kind；Also include mastoid operation dilator, table dental to bore；The mastoid process hand
Art dilator is bored with the table dental and is arranged on the operating platform.
It is preferred that, can embodiment as one kind；The side of the operating platform is additionally provided with support, the support and set
It is equipped with winding bore.
It is preferred that, can embodiment as one kind；The side of the operating platform is additionally provided with storage box；The storage box
Thimerosal and sterilized cotton ball, scalpel are placed for accommodating.
Correspondingly, present invention also offers a kind of rat test platform application method, comprise the following steps：
Step S100, to rat implement anesthesia procedure, be fixed on after anaesthetizing successfully on operating platform；First adjust four
At the position for the adaptation for sliding foot fixation kit, operation is separately fixed at by sliding foot fixation kit by the four limbs of rat
On platform；The head of rat is subjected to three-point mount using head fixation kit simultaneously；
Step S200, adjusting post vertical direction position, are lived using three-dimensional manipulating arm X-axis, Y-axis, three directions of Z axis
It is dynamic, the Different brain region at skull position hole to be drilled or rat head is accurately positioned；
Step S300, the skull cut using mastoid operation dilator to rat carry out exposing surgical field of view, are completely separated
The skull of periosteum and exposed Rats；
Step S400, the drilling operation using table dental brill Rat calvarial progress stimulation hole and peep hole；
Step S500, electrode stimulating component is inserted in the stimulation hole and sets up electrode model, the electrode model is entered
The fixed operation of row suture and sterilizing operation.
It is preferred that, can embodiment as one kind；In the step s 100；It is described by sliding foot fixation kit by rat
Four limbs be separately fixed on operating platform include specific steps：
Step S110, using geometrical clamp by rat four limbs be firmly fixed by socket slide foot fixation kit on；While institute
The two rows perforation for stating slip foot fixation kit both sides both passes through band rope, is tightened rat four limbs by band rope.
Compared with prior art, this have the advantage that：
A kind of rat test platform and rat test platform application method that the present invention is provided, its rat test platform are main by grasping
Make platform and a head fixation kit, four slip foot fixation kits and thermostatically-controlled equipment and cold light source LED illumination
The structure compositions such as lamp；
Wherein, the head fixation kit is used to rat head is fixed and is accurately positioned；Four foots that slide are consolidated
Determine the four limbs that component is respectively used to fix the rat；Each slip foot fixation kit is correspondingly arranged on two rows and worn
Hole, and two rows perforation be arranged separately on it is described slip foot fixation kit both sides operating platform surface on；Two rows are corresponding
The perforation between supporting be provided with band rope；Any one limb of rat passes through the slip foot fixation kit shape
Into once fixing, and secondary fixation is formed by the band rope in the corresponding perforation of two rows.The thermostatically-controlled equipment
Body temperature for controlling the rat；The cold light source LED illumination lamp is used to provide lighting source；In addition, the three-dimensional manipulating
Arm is used for by the movable three-dimensional manipulating arm in X-axis, Y-axis, three directions of Z axis, and then realizes to sphenotresia position or rat
The Different brain region on head is accurately positioned.
Rat test platform and rat test platform application method that the present invention is provided, it is in electrode stimulating model experiment to big
Mouse implements miscellaneous function, i.e., be fixed including rat four limbs are fixed, to the head of rat, to the skull operation of rat
Position such as is strutted and drilled the assist technical operations；The rat test platform that the present invention is provided, it is complete with simple structure, function
Kind, it carries out electrode stimulating model experiment for rat and provides significant booster action.
Brief description of the drawings
, below will be to specific in order to illustrate more clearly of the specific embodiment of the invention or technical scheme of the prior art
The accompanying drawing used required in embodiment or description of the prior art is briefly described, it should be apparent that, in describing below
Accompanying drawing is some embodiments of the present invention, for those of ordinary skill in the art, before creative work is not paid
Put, other accompanying drawings can also be obtained according to these accompanying drawings.
Fig. 1 is the rat schematic top plan view in rat test platform provided in an embodiment of the present invention；
Fig. 2 is the dimensional structure diagram of rat test platform provided in an embodiment of the present invention；
Fig. 3 shows for the partial enlargement structure of the slip foot fixation kit in rat test platform provided in an embodiment of the present invention
It is intended to；
Description of reference numerals：
Rat A；
Operating platform 1；
Supporting leg 2；
Slide foot fixation kit 3；Slideway 31；Sliding block 32；Geometrical clamp 33；
Head fixation kit 4；Tooth fixed mechanism 41；Ear bar 42；
Thermostatically-controlled equipment 5；Electric blanket 51；Body temperature screen 52；Rat anus temperature digital clinical thermometer 53；
Cold light source LED illumination lamp 6；
Column 7；Three-dimensional manipulating arm 71；
Support 8；
Perforation 9；
Band rope 10.
Embodiment
Technical scheme is clearly and completely described below in conjunction with accompanying drawing, it is clear that described implementation
Example is a part of embodiment of the invention, rather than whole embodiments.Based on the embodiment in the present invention, ordinary skill
The every other embodiment that personnel are obtained under the premise of creative work is not made, belongs to the scope of protection of the invention.
In the description of the invention, it is necessary to explanation, term " " center ", " on ", " under ", "left", "right", " vertical ",
The orientation or position relationship of the instruction such as " level ", " interior ", " outer " be based on orientation shown in the drawings or position relationship, merely to
Be easy to the description present invention and simplify description, rather than indicate or imply signified device or element must have specific orientation,
With specific azimuth configuration and operation, therefore it is not considered as limiting the invention.In addition, term " first ", " second ",
" the 3rd " is only used for describing purpose, and it is not intended that indicating or implying relative importance.
In the description of the invention, it is necessary to illustrate, unless otherwise clearly defined and limited, term " installation ", " phase
Even ", " connection " should be interpreted broadly, for example, it may be being fixedly connected or being detachably connected, or be integrally connected；Can
To be mechanical connection or electrical connection；Can be joined directly together, can also be indirectly connected to by intermediary, Ke Yishi
The connection of two element internals.For the ordinary skill in the art, with concrete condition above-mentioned term can be understood at this
Concrete meaning in invention.
The present invention is described in further detail below by specific embodiment and with reference to accompanying drawing.
Referring to Fig. 2, Fig. 3, a kind of rat test platform provided in an embodiment of the present invention, including operating platform 1 be fixedly connected
Multiple supporting legs 2 in the bottom of operating platform 1；
Four are additionally provided with the operating platform 1 and slides foot fixation kit 3, head fixation kit 4 and a perseverance
Temperature control device 5 and cold light source LED illumination lamp 6；The head fixation kit 4 is used to fix on rat A head and accurately fixed
Position；Four slip foot fixation kits 3 are respectively used to fix the four limbs of the rat A (i.e. referring to Fig. 1), and the slip
Foot fixation kit 3 and rat A four limbs are corresponded；The thermostatically-controlled equipment 5 is used for the body for controlling the rat A
Temperature；The cold light source LED illumination lamp 6 is used to provide lighting source；
In four slip foot fixation kits, the arranged distribution of slip foot fixation kit 3 is in the behaviour two-by-two
Make the both sides of the axis of platform 1；The slip foot fixation kit 3 is slidably matched along the surface of operating platform 1；Each
The slip foot fixation kit 3 is all correspondingly arranged on two rows perforation 9, and two rows perforation 9 is arranged separately on the slip foot
On the surface of operating platform 1 of the both sides of fixation kit 3；It is supporting between the corresponding perforation 9 of two rows to be provided with band rope
10；
Any one limb of the rat A is formed by the slip foot fixation kit 3 and once fixed, and passes through two
Band rope 10 in the corresponding perforation 9 of row forms secondary fixation.
The primary structure for analyzing rat test platform provided in an embodiment of the present invention is understood：Its rat test platform is main by grasping
Make platform and four are slided the structure compositions such as foot fixation kit；Wherein, the foot fixation kit that slides is along the operation
Platform is slidably matched along a direction；Each slip foot fixation kit is correspondingly arranged on two rows perforation, and two rows wear
Hole is arranged separately on the operating platform surface of the both sides of the slip foot fixation kit；The corresponding perforation of two rows it
Between supporting be provided with band rope；Any one limb of rat is once fixed by the slip foot fixation kit formation,
And secondary fixation is formed by the band rope in the corresponding perforation of two rows.
The rat test platform that the present invention is provided, it is implemented miscellaneous function to rat in electrode stimulating model experiment, that is, wrapped
Include and rat four limbs are fixed, the head of rat is fixed, the skull operation position of rat is strutted and bored
The assist technical operations such as hole；The rat test platform that the present invention is provided, with simple structure, perfect in shape and function, it is that rat carries out electricity
Polar stimulation model experiment provides significant booster action.
Detailed once is done to the concrete structure and particular technique effect of rat test platform provided in an embodiment of the present invention below
Describe in detail bright：
It is preferred that, can embodiment as one kind；As shown in figure 3, the slip foot fixation kit 3 specifically includes slideway
31st, it is arranged on the sliding block 32 on the slideway 31；And it is fixedly connected with geometrical clamp 33 on the sliding block 32；The sliding block 32 is relative
The slideway 31 is slidably matched.
It should be noted that it will be apparent that the four limbs for how fixing rat are technical problems common in testing；It is of the invention real
The rat test platform of example offer is applied, which employs the design structure for sliding foot fixation kit, it can not only adjust rat and consolidate
Fixed position, while it can also carry out adaptability regulation according to the rat of different building shape.
Sliding foot fixation kit 3, it is main by slideway 31, the sliding block 32 being arranged on the slideway 31 and fixation
Folder 33 is constituted；When specifically used, adjusting slider 32 is in the position of slideway 31, that is, when being adjusted to the position adapted to, opens and fixes
33 sets of folder is connected to after rat, realizes snap lock.
It is preferred that, can embodiment as one kind；The geometrical clamp 33 specifically includes the clip of two c-type shapes, and two
The clip of individual c-type shape is oppositely arranged, and formation is snapped fit attachment.
It should be noted that above-mentioned geometrical clamp 33 specifically includes the clip of two c-type shapes, can be real by snap
Now to the first time locking operation of rat four limbs.Then bundled by band rope 10, and then realize that secondary locking is operated.
It is preferred that, can embodiment as one kind；The head fixation kit 4 specifically includes tooth fixed mechanism 41 and two
Individual ear bar 42；Wherein, the tooth fixed mechanism is arranged on the front end of the axis of the operating platform, and two ear bars are set
Put the both sides in the axis of the operating platform；The tooth fixed mechanism is used for the tooth for fixing the rat；Two institutes
State ear bar and insert the external auditory meatus of the rat respectively for fixing the rat both sides.
It should be noted that above-mentioned tooth fixed mechanism its be arranged on operating platform axis front end, it is mainly used
It is fixed in the head end to rat；Cooperate with two ear bars that the both sides of rat are fixed simultaneously, just can so pass through three
Point type fixed form is formed fixes to the stable of rat head.Meanwhile, above-mentioned ear bar tip is obtuse angle, will not be damaged under normal circumstances
Hinder rat ear-drum, protection animal is injury-free, adapt to chronicity experiment.
It is preferred that, can embodiment as one kind；The thermostatically-controlled equipment 5 specifically includes electric blanket 51, body temperature screen
52 and rat anus temperature digital clinical thermometer 53；The rat anus temperature digital clinical thermometer respectively with the electric blanket and the body temperature screen
Curtain electrical connection.
It should be noted that rat anus temperature digital clinical thermometer can measure the body temperature of rat in real time, and by being connected thereto
Body temperature screen carry out body temperature show；The formation feedback regulation of connected electric blanket can also be passed through simultaneously；For example：It is current big
During the hypothermia of mouse, it can control to start the operation of electric blanket heated in real-time temperature；Above-mentioned electric blanket is laid on described
On operating platform.To sum up, need to keep in surgical procedure to cover electric blanket on thermostasis, operating platform, operation can be kept
During animal heat.
In addition, above-mentioned rat anus temperature digital clinical thermometer can select the clinical thermometer using diversified forms, but it preferably makes
Use BAT-12 digital thermometers；The digital thermometer, which is one, is used for the instrument of biological temperature and laboratory temperature measurement,
The features such as it has widely used, reaction fast, accuracy height, good stability, numerical monitor, its analog output signal can be with
Computer and register instrument connection are used, and it is equipped with rat temp probe.
It is preferred that, can embodiment as one kind；It is additionally provided with column 7, the column 7 and sets on the operating platform 1
It is equipped with three-dimensional manipulating arm 71；Wherein, the three-dimensional manipulating arm specifically includes X-axis operation travelling arm, Y-axis operation travelling arm and Z axis
Operate travelling arm；The three-dimensional manipulating arm is used for by X-axis, Y-axis, three directions of Z axis to skull position hole to be drilled or rat head
The Different brain region in portion is accurately positioned.
It should be noted that the three-dimensional manipulating arm is used for by the movable three-dimensional manipulating in X-axis, Y-axis, three directions of Z axis
Arm, detachably, can specifically be positioned to mouse brain.
It is preferred that, can embodiment as one kind；The above-mentioned cold light source LED illumination lamp 6 is specially the double optical fiber cold light of LED
Source.
It should be noted that above-mentioned cold light source LED illumination lamp 6 can select the illuminating lamp using diversified forms；But
In the embodiment of the present invention, it preferably uses the double fibre-optical cold light source -20W/90-260V of LED；The fine cold light source of such LED light is used
High-power single chip encapsulation LED does light source, and specially designs the kohler's illumination condenser system of 5 optical lens compositions, by big work(
Rate LED strong light is efficiently couple to fibre-optic bundle export, with light efficiency height, energy-conservation, low caloric value, service life length, makes an uproar
Many advantages, such as sound is small.
It is preferred that, can embodiment as one kind；The side of the operating platform 1 is additionally provided with support 8, the support 8
On be provided with winding bore.
It should be noted that being provided with winding bore on above-mentioned support 8, it, which is mainly, facilitates some band line electric equipments to use
When, it is easy to the winding of wire, it is to avoid because of the normal operating that equipment wire is long and influences experiment to perform the operation.
It is preferred that, can embodiment as one kind；The rat test platform also includes mastoid operation dilator (not shown)
(not shown) is bored with table dental；The mastoid operation dilator and the table dental are drilled with and put on the operational platform.
It should be noted that above-mentioned mastoid operation dilator its rat can be operated with very convenient.Using
The design of said structure, with reference to the mastoid operation dilator of surgery, operation is light, and a people can just operate, and cost is relatively low.
In addition, implementing drilling operation to the skull of rat, it can select to use a variety of surgical instruments, but the present invention is implemented
Example its preferably use table dental brill；Because table dental bores it and uses the stainless steel bit of ultrahigh hardness, with extremely outstanding
Antirust, corrosion-resistant, abrasion performance (high rigidity) performance and preferable shock resistance, it is particularly suitable for meiofauna as rat
Sphenotresia operation.
It is preferred that, can embodiment as one kind；The side of the operating platform is additionally provided with storage box；The storage box
Thimerosal and sterilized cotton ball, scalpel are placed for accommodating.
It should be noted that its main function of storage box is to accommodate to place the hand such as thimerosal and sterilized cotton ball, scalpel
The conventional device of art experiment；The storage box facilitates the operation of operation, above-mentioned operation can be commonly used into device and all be placed on glove
In case, it can take up and use at any time in surgical procedure.
Above-mentioned its size of rat test platform is preferably used：The length of operating platform is 350mm, and the width of operating platform is
250mm, the whole height of its rat test platform is 40mm.Wherein the thickness of operating platform is 2mm.What aforementioned four supporting leg was consolidated
It is fixed on four edges of operating platform；The rat test platform and rat test platform application method controllability are strong, equipment can
It is strong by property.
Specific implementation to rat test platform application method provided in an embodiment of the present invention and particular technique effect below
Do and describe in detail：
Correspondingly, present invention also offers a kind of rat test platform application method, comprise the following steps：
Step S100, to rat implement anesthesia procedure, be fixed on after anaesthetizing successfully on operating platform；First adjust four
At the position for the adaptation for sliding foot fixation kit, operation is separately fixed at by sliding foot fixation kit by the four limbs of rat
On platform；The head of rat is subjected to three-point mount using head fixation kit simultaneously；
Step S200, adjusting post vertical direction position, are lived using three-dimensional manipulating arm X-axis, Y-axis, three directions of Z axis
It is dynamic, the Different brain region at skull position hole to be drilled or rat head is accurately positioned (i.e. it should be noted that to rat head
It is accurately positioned to drill, further carries out positioning to each brain area in addition and be easy to be administered or carry out electro physiology detection)；
Step S300, the skull cut using mastoid operation dilator to rat carry out exposing surgical field of view, are completely separated
The skull of periosteum and exposed Rats；
Step S400, the drilling operation using table dental brill Rat calvarial progress stimulation hole and peep hole；
Step S500, electrode stimulating component is inserted in the stimulation hole and sets up electrode model, the electrode model is entered
The fixed operation of row suture and sterilizing operation.
It is preferred that, can embodiment as one kind；In the step s 100；It is described by sliding foot fixation kit by rat
Four limbs be separately fixed on operating platform include specific steps：
Step S110, using geometrical clamp by rat four limbs be firmly fixed by socket slide foot fixation kit on；While institute
The two rows perforation for stating slip foot fixation kit both sides both passes through band rope, is tightened rat four limbs by band rope.
Rat test platform and rat test platform application method provided in an embodiment of the present invention has the technology of following aspect excellent
Gesture：
First, rat test platform provided in an embodiment of the present invention, it has special structure design, and connects between concrete structure
Connect, be laid out etc. all to have and cleverly designing；Rat test platform provided in an embodiment of the present invention, its more reasonable, system tray of design
Structure is more novel, function is more perfect.
2nd, rat test platform provided in an embodiment of the present invention, any one limb of its rat is fixed by sliding foot
Component formation is once fixed, and forms secondary fixation by the band rope in the corresponding perforation of two rows.It is big that the present invention is provided
Mouse testing stand, it implements miscellaneous function in electrode stimulating model experiment to rat, i.e., including rat four limbs are fixed, right
The head of rat is fixed, and the assist technical operations such as strutted and drilled to the skull operation position of rat；The present invention
The rat test platform of offer, with simple structure, perfect in shape and function, it carries out electrode stimulating model experiment for rat and provided significantly
Booster action.
3rd, rat test platform and rat test platform application method provided in an embodiment of the present invention, it greatly facilitates to big
Mouse is operated.Using the design of said structure, mastoid operation dilator and table dental with reference to surgery bore and
Foot fixation kit is slided, easy to operate, a people can just operate, and cost is relatively low, and experiment operating time is greatly shortened.
Many significant technical advantages based on more than, rat test platform and rat test platform application method that the present invention is provided
Good market prospects and economic benefit will be brought.
Finally it should be noted that：Various embodiments above is merely illustrative of the technical solution of the present invention, rather than its limitations；To the greatest extent
The present invention is described in detail with reference to foregoing embodiments for pipe, it will be understood by those within the art that：Its according to
The technical scheme described in foregoing embodiments can so be modified, or which part or all technical characteristic are entered
Row equivalent substitution；And these modifications or replacement, the essence of appropriate technical solution is departed from various embodiments of the present invention technology
The scope of scheme.
Claims (10)
1. a kind of rat test platform, it is characterised in that including operating platform and be fixedly connected on many of the operating platform bottom
Individual supporting leg；
A head fixation kit, four slip foot fixation kits and thermostatic control dress are additionally provided with the operating platform
Put and cold light source LED illumination lamp；The head fixation kit is used to rat head is fixed and is accurately positioned；Four slips
Foot fixation kit is respectively used to fix the four limbs of the rat, and the slip foot fixation kit and the four limbs of the rat
Correspond；The thermostatically-controlled equipment is used for the body temperature for controlling the rat；The cold light source LED illumination lamp is used to provide photograph
Mingguang City source；
In four slip foot fixation kits, the slip foot fixation kit arranged distribution is in the operating platform two-by-two
Axis both sides；The slip foot fixation kit is slidably matched along the operating platform surface；Each slip
Foot fixation kit is all correspondingly arranged on two rows perforation, and two rows perforation is arranged separately on the two of the slip foot fixation kit
On the operating platform surface of side；It is supporting between the corresponding perforation of two rows to be provided with band rope；
Any one limb of the rat is once fixed by the slip foot fixation kit formation, and relative by two rows
The band rope in the perforation answered forms secondary fixation.
2. rat test platform as claimed in claim 1, it is characterised in that
It is described to slide the sliding block that foot fixation kit specifically includes slideway, is arranged on the slideway；And it is fixed on the sliding block
It is connected with geometrical clamp；The relatively described slideway of the sliding block is slidably matched.
3. rat test platform as claimed in claim 2, it is characterised in that
The geometrical clamp specifically includes the clip of two c-type shapes, and the clip of two c-type shapes is oppositely arranged, and shape
Into snapping fit attachment.
4. rat test platform as claimed in claim 3, it is characterised in that
The thermostatically-controlled equipment specifically includes electric blanket, body temperature screen and rat anus temperature digital clinical thermometer；The rat anus temperature
Digital clinical thermometer is electrically connected with the electric blanket and the body temperature screen respectively.
5. rat test platform as claimed in claim 3, it is characterised in that
The head fixation kit specifically includes tooth fixed mechanism and two ear bars；
Wherein, the tooth fixed mechanism is arranged on the front end of the axis of the operating platform, and two ear bars are arranged on
The both sides of the axis of the operating platform；The tooth fixed mechanism is used for the tooth for fixing the rat；Two ears
The external auditory meatus that bar inserts the rat respectively is used to fix the rat both sides.
6. rat test platform as claimed in claim 5, it is characterised in that
It is additionally provided with the operating platform on column, the column and is provided with three-dimensional manipulating arm；
Wherein, the three-dimensional manipulating arm specifically includes X-axis operation travelling arm, Y-axis operation travelling arm and Z axis operation travelling arm；Institute
State three-dimensional manipulating arm be used for by X-axis, Y-axis, three directions of Z axis it is movable to skull position hole to be drilled or the different brains of rat head
Area is accurately positioned.
7. rat test platform as claimed in claim 6, it is characterised in that
Also include mastoid operation dilator, table dental to bore；The mastoid operation dilator is bored with the table dental and is arranged on
On the operating platform.
8. rat test platform as claimed in claim 3, it is characterised in that
The side of the operating platform is additionally provided with support, the support and is provided with winding bore.
9. a kind of rat test platform application method, it is characterised in that comprise the following steps：
Step S100, to rat implement anesthesia procedure, be fixed on after anaesthetizing successfully on operating platform；First adjust four slips
At the position of the adaptation of foot fixation kit, operating platform is separately fixed at by sliding foot fixation kit by the four limbs of rat
On；The head of rat is subjected to three-point mount using head fixation kit simultaneously；
Step S200, adjusting post vertical direction position, it is right using three-dimensional manipulating arm X-axis, Y-axis, three direction activities of Z axis
Skull position hole to be drilled or the Different brain region of rat head are accurately positioned；
Step S300, the skull cut using mastoid operation dilator to rat carry out exposing surgical field of view, are completely separated periosteum
And the skull of exposed Rats；
Step S400, the drilling operation using table dental brill Rat calvarial progress stimulation hole and peep hole；
Step S500, electrode stimulating component is inserted in the stimulation hole and sets up electrode model, the electrode model is stitched
Close fixed operation and sterilizing operation.
10. rat test platform application method as claimed in claim 9, it is characterised in that
In the step s 100；It is described to be included by sliding foot fixation kit and the four limbs of rat being separately fixed on operating platform
Specific steps：
Step S110, using geometrical clamp by rat four limbs be firmly fixed by socket slide foot fixation kit on；While the cunning
The two rows perforation of action spot portion fixation kit both sides both passes through band rope, is tightened rat four limbs by band rope.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710344274.6A CN107198590A (en) | 2017-05-16 | 2017-05-16 | Rat test platform and rat test platform application method |
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| CN201710344274.6A CN107198590A (en) | 2017-05-16 | 2017-05-16 | Rat test platform and rat test platform application method |
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| CN107198590A true CN107198590A (en) | 2017-09-26 |
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| CN201710344274.6A Pending CN107198590A (en) | 2017-05-16 | 2017-05-16 | Rat test platform and rat test platform application method |
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| CN108078648A (en) * | 2018-01-23 | 2018-05-29 | 王存金 | A kind of mouse Nerve surgical bed |
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| CN110327130A (en) * | 2019-06-14 | 2019-10-15 | 北京航空航天大学 | A kind of multi-functional fixed platform of embedded zoopery of temperature control |
| WO2020191948A1 (en) * | 2019-03-22 | 2020-10-01 | 中国科学院深圳先进技术研究院 | Animal surgical table |
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| CN115381586A (en) * | 2022-10-28 | 2022-11-25 | 中国人民解放军军事科学院军事医学研究院 | Experimental animals operation fixing device |
| CN116370135A (en) * | 2023-06-05 | 2023-07-04 | 中国人民解放军军事科学院军事医学研究院 | Instrument is constructed to bacterial meningitis experiment mouse |
| CN116370135B (en) * | 2023-06-05 | 2023-09-19 | 中国人民解放军军事科学院军事医学研究院 | Instrument is constructed to bacterial meningitis experiment mouse |
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