CN107184926A - A kind of Chinese medicine composition of auxiliary treatment gynecologic malignant tumor - Google Patents

A kind of Chinese medicine composition of auxiliary treatment gynecologic malignant tumor Download PDF

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Publication number
CN107184926A
CN107184926A CN201710318927.3A CN201710318927A CN107184926A CN 107184926 A CN107184926 A CN 107184926A CN 201710318927 A CN201710318927 A CN 201710318927A CN 107184926 A CN107184926 A CN 107184926A
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parts
radix
chinese medicine
medicine composition
chinese
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杨娟
杨娜
龙文义
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Huanghe Science and Technology College
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Huanghe Science and Technology College
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Priority to CN201710318927.3A priority Critical patent/CN107184926A/en
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    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9068Zingiber, e.g. garden ginger
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    • A61K35/56Materials from animals other than mammals
    • A61K35/57Birds; Materials from birds, e.g. eggs, feathers, egg white, egg yolk or endothelium corneum gigeriae galli
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    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction

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Abstract

The invention belongs to technical field of traditional Chinese medicines, especially a kind of Chinese medicine composition of auxiliary treatment gynecologic malignant tumor, solve prior art operation, radiotherapy etc. and send an expedition against therapy damage healthy tendency, tumor recurrence rate is high, the problem of quality of life of patients is reduced, following scheme is now proposed, includes the raw material of following parts by weight:10 30 parts of RADIX ACONITI LATERALIS PREPARATA, 10 30 parts of radix glycyrrhizae, 15 50 parts of oldenlandia diffusa, 15 30 parts of folium isatidis, 15 30 parts of radix glehniae, 20 50 parts of subprostrate sophora, 20 50 parts of evodia rutaecarpa, 20 50 parts of Chinese cassia tree, 10 30 parts of ginseng, 10 20 parts of wilsonii, 10 30 parts of the tuber of pinellia.Treatment cycle of the present invention is short, it is rapid-action, and the defect that traditional remedies healthy tendency is deficient, damp and hot silt is malicious is compensate for, by improving body's immunity, excite and improve body to automatically adjust, regulation incretion balance is guarded the emperor guarantor's boat extension life cycle so as to be reached for operation and radiotherapy.

Description

A kind of Chinese medicine composition of auxiliary treatment gynecologic malignant tumor
Technical field
The present invention relates to technical field of traditional Chinese medicines, more particularly to a kind of Chinese medicine composition of auxiliary treatment gynecologic malignant tumor.
Background technology
Gynecologic malignant tumor includes oophoroma, cervical carcinoma, malignant trophoblastic tumor, vulva and carcinoma of vagina, in recent years, The country is performed the operation with doctor trained in Western medicine, and radiotherapy is under main treating cancer overall background, traditional Chinese medicine auxiliary treatment not only effectively makes up doctor trained in Western medicine deficiency, more Body's immunity can be improved, improves overall health of patients, so as to improve life in patients.Operation, radiotherapy etc. send an expedition against therapy not only Healthy tendency is damaged, also tends to reduce immunologic function and impression quality is smoothed out, and all there is the positive deficiency of vital energy in existing Traditional Chinese Medicine therapy The defect of damage, the damp and hot poison that becomes silted up, this law advocates the treatment that righting is laid equal stress on eliminating evil, there is supplementing qi and nourishing yin, the work(of softening hardness to remove stagnation of food, with righting Reinforcing is that core protects marrow simultaneously to improve its hematopoiesis function, enhancing disappears by improving body's immunity, regulation incretion balance Change absorption function, excite and improve body and automatically adjust, correct negative and positive and deviate, in line with Hard masses must be disintegrated, Enlarged nodes must be resolved, and the person of staying attacks It, what stagnant person led principle, to attack based on heresy, so as to be reached for operation and radiotherapy is guarded the emperor guarantor's boat extension life cycle, improves life The purpose of quality.Based on above statement, the present invention proposes a kind of Chinese medicine composition of auxiliary treatment gynecologic malignant tumor.
Therefore in disclosed application number 201610255114.X, propose to improve postoperative gynecologic malignant tumor patient, chemotherapy and The quality of life of radiotherapy, though it is with low cost, work slower, treatment cycle is long.
Separately there are application number 201610152287.9, it is nausea and vomiting after kind of auxiliary treatment gynecologic malignant tumor chemotherapy Chinese medicine composition, therapeutic purposes are single, it is impossible to comprehensive auxiliary treatment chemotherapy, it is impossible to reach raising body's immunity, improve complete Body situation, DeGrain is improved to improving life in patients.
The content of the invention
Therapy damage healthy tendency is sent an expedition against the invention aims to solving operation, radiotherapy etc. present in prior art, it is swollen Knurl high recurrence rate shortcoming, and a kind of Chinese medicine composition of the auxiliary treatment gynecologic malignant tumor proposed, which solve existing Chinese and Western The problem of curing deficient healthy tendency in treating, damp and hot silt poison.Wherein adjutant adds jujube, turtle shell, ganoderma lucidum and is effectively improved patient's dizziness not Dormancy, palpitation, neurasthenia, consumptive disease cough and asthma symptom, not only improve tumor patient immunity, and conditioning patient's taste, effectively Suppress symptoms of emesis and improvement patient's appetite after postoperative and radiotherapy.Ministerial drug Radix Codonopsis, the raw Radix Astragali, root of Chinese trichosanthes, hairyvein agrimony, reticulate millettia, Evodia rutaecarpa, Chinese cassia tree, notopterygium root, the membrane of a chicken's gizzard, Divine Comedy, wilsonii increase patient's cyclic metabolism, are effective against allergy after operation and radiotherapy Symptom.This traditional Chinese medicine composition for treating effect is comprehensive and cheap, and the effect cycle is short, substantially increases malignant tumor patient life Deposit quality.
A kind of Chinese medicine composition of auxiliary treatment gynecologic malignant tumor, includes the raw material of following parts by weight:Tuber of pinellia 10-30 Part, 10-30 parts of RADIX ACONITI LATERALIS PREPARATA, 10-30 parts of Radix Codonopsis, raw 10-30 parts of the Radix Astragali, 10-30 parts of root of Chinese trichosanthes, 20-50 parts of hairyvein agrimony, chicken blood 20-50 parts of rattan, 20-50 parts of evodia rutaecarpa, 20-50 parts of Chinese cassia tree, 3-15 parts of notopterygium root, 10-25 parts of the membrane of a chicken's gizzard, 10-25 parts of Divine Comedy, thorn It is 5-20 parts of slender acanthopanax, 10-25 parts of Poria cocos, 10-25 parts of pig Poria cocos, 10-25 parts of Radix Angelicae Sinensis, 10-30 parts of the bighead atractylodes rhizome, 10-30 parts of radix glycyrrhizae, big 10-25 parts of jujube, 7-15 parts of Fructus Aurantii, 10-30 parts of the red sage root, 10-30 parts of radix scrophulariae, 10-30 parts of folium isatidis, 15-30 parts of radix glehniae, mountain beans It is 20-50 parts of root, 10-30 parts of ginseng, 5-20 parts of blood clam, 15-30 parts of rhizoma zingiberis, 15-45 parts of Sculellaria barbata, 15-50 parts of fructus amomi, windproof 5-30 parts, 5-35 parts of sealwort, 20-50 parts of spina date seed, 15-50 parts of oldenlandia diffusa, 15-45 parts of turtle shell, 15-50 parts of coix seed and 15-45 parts of ganoderma lucidum.
It is preferred that, a kind of Chinese medicine composition of auxiliary treatment gynecologic malignant tumor, including following raw material:Half Summer 11-29 part, 11-29 parts of RADIX ACONITI LATERALIS PREPARATA, 11-29 parts of Radix Codonopsis, raw 11-29 parts of the Radix Astragali, 11-29 parts of root of Chinese trichosanthes, hairyvein agrimony 21-49 Part, 21-49 parts of reticulate millettia, 21-49 parts of evodia rutaecarpa, 21-49 parts of Chinese cassia tree, 4-14 parts of notopterygium root, 11-24 parts of the membrane of a chicken's gizzard, Divine Comedy 11-24 Part, 6-19 parts of wilsonii, 11-24 parts of Poria cocos, 11-29 parts of pig Poria cocos, 11-24 parts of Radix Angelicae Sinensis, 11-29 parts of the bighead atractylodes rhizome, radix glycyrrhizae 11-29 Part, 11-24 parts of jujube, 8-14 parts of Fructus Aurantii, 11-29 parts of the red sage root, 11-29 parts of radix scrophulariae, 11-29 parts of folium isatidis, radix glehniae 16-29 Part, 21-49 parts of subprostrate sophora, 11-29 parts of ginseng, 6-19 parts of blood clam, 16-29 parts of rhizoma zingiberis, 16-44 parts of Sculellaria barbata, fructus amomi 16- 49 parts, windproof 6-29 parts, 6-34 parts of sealwort, 21-49 parts of spina date seed, 16-49 parts of oldenlandia diffusa, 16-44 parts of turtle shell, Job's tears 16-44 parts of 16-49 parts of benevolence and ganoderma lucidum.
It is preferred that, a kind of Chinese medicine composition of auxiliary treatment gynecologic malignant tumor, including following raw material:Half Summer 12-28 part, 12-28 parts of RADIX ACONITI LATERALIS PREPARATA, 12-28 parts of Radix Codonopsis, raw 12-28 parts of the Radix Astragali, 12-28 parts of root of Chinese trichosanthes, hairyvein agrimony 22-48 Part, 22-48 parts of reticulate millettia, 22-48 parts of evodia rutaecarpa, 22-48 parts of Chinese cassia tree, 5-13 parts of notopterygium root, 12-23 parts of the membrane of a chicken's gizzard, Divine Comedy 12-23 Part, 7-18 parts of wilsonii, 12-23 parts of Poria cocos, 12-28 parts of pig Poria cocos, 12-23 parts of Radix Angelicae Sinensis, 12-28 parts of the bighead atractylodes rhizome, radix glycyrrhizae 12-28 Part, 12-28 parts of jujube, 9-13 parts of Fructus Aurantii, 12-28 parts of the red sage root, 12-28 parts of radix scrophulariae, 12-28 parts of folium isatidis, radix glehniae 17-28 Part, 22-48 parts of subprostrate sophora, 12-28 parts of ginseng, 7-18 parts of blood clam, 17-28 parts of rhizoma zingiberis, 17-43 parts of Sculellaria barbata, fructus amomi 17- 48 parts, windproof 7-28 parts, 7-33 parts of sealwort, 22-48 parts of spina date seed, 17-48 parts of oldenlandia diffusa, 17-48 parts of turtle shell, Job's tears 17-43 parts of 17-48 parts of benevolence and ganoderma lucidum.
It is preferred that, a kind of Chinese medicine composition of auxiliary treatment gynecologic malignant tumor, including following raw material:Half 20 parts of summer, 15 parts of RADIX ACONITI LATERALIS PREPARATA, 15 parts of Radix Codonopsis, raw 15 parts of the Radix Astragali, 15 parts of root of Chinese trichosanthes, 25 parts of hairyvein agrimony, 25 parts of reticulate millettia, evodia rutaecarpa 20 parts, 20 parts of Chinese cassia tree, 10 parts of notopterygium root, 15 parts of the membrane of a chicken's gizzard, 15 parts of Divine Comedy, 10 parts of wilsonii, 15 parts of Poria cocos, 15 parts of pig Poria cocos, 20 parts of Radix Angelicae Sinensis, 15 parts of the bighead atractylodes rhizome, 15 parts of radix glycyrrhizae, 15 parts of jujube, 10 parts of Fructus Aurantii, 15 parts of the red sage root, 15 parts of radix scrophulariae, 15 parts of folium isatidis, north 15 parts of the root of straight ladybell, 20 parts of subprostrate sophora, 12 parts of ginseng, 10 parts of blood clam, 15 parts of rhizoma zingiberis, 20 parts of Sculellaria barbata, 10 parts of fructus amomi, windproof 10 20 parts of part, 10 parts of sealwort, 25 parts of spina date seed, 20 parts of oldenlandia diffusa, 20 parts of turtle shell, 20 parts of coix seed and ganoderma lucidum.
It is preferred that, a kind of Chinese medicine composition of auxiliary treatment gynecologic malignant tumor, the tuber of pinellia is monarch in the composition Medicine, RADIX ACONITI LATERALIS PREPARATA, Radix Codonopsis, the raw Radix Astragali, root of Chinese trichosanthes, hairyvein agrimony, reticulate millettia, evodia rutaecarpa, Chinese cassia tree, notopterygium root, the membrane of a chicken's gizzard, Divine Comedy, thorn five Add as ministerial drug, Poria cocos, pig Poria cocos, Radix Angelicae Sinensis, the bighead atractylodes rhizome, radix glycyrrhizae, jujube, Fructus Aurantii, the red sage root, radix scrophulariae, folium isatidis, radix glehniae, subprostrate sophora, Ginseng, blood clam, rhizoma zingiberis, Sculellaria barbata, fructus amomi, windproof, sealwort, spina date seed, oldenlandia diffusa, turtle shell, coix seed, ganoderma lucidum combination Into adjutant.
It is preferred that, the tuber of pinellia and notopterygium root ratio are 2-4:1-8.
It is preferred that, the wilsonii is with being 1.5-3.5 with the ratio of notopterygium root:1-3.
It is preferred that, a kind of preparation method of the Chinese medicine composition of auxiliary treatment gynecologic malignant tumor comprises the following steps:
S1. claim 1 Chinese medicine is prepared:Notopterygium root picks impurity, cleans, runs through, and cuts into slices, dries;Turtle shell takes Carapax Trionycis (processed), Sandy soil are put in iron pan and heated, it is loose to sandy soil, it is put into net turtle shell and fries slightly yellow to epidermis, taking-up weeds out sandy soil, is put into vinegar basin Inside slightly soak 10-30 minute, take out dry Carapax Trionycis (processed);RADIX ACONITI LATERALIS PREPARATA is cut into slices, with sand scald to heave and it is micro- discoloration it is stand-by;
S2. it is cooked by slow fire 8-30 minutes in S1, the monarch drug in a prescription tuber of pinellia is first put into, adds the notopterygium root prepared in S1, turtle shell, system Monkshood, is cooked by slow fire after 5-15 minutes and decoction is mixed with adjutant;
S3. the Chinese medicine prepared in S1-S2 and adjutant are collectively disposed at into container to soak 3-5 hours, normal pressure decocts 20-60 points Zhong Hou, filters out decoction, and the water decoction A and mixture B adjutants for obtaining Chinese medicine composition of the present invention are collectively disposed at immersion 1- in container More than 3 hours, after normal pressure is decocted 10-50 minutes, decoction is filtered out, the water decoction A and mixture of Chinese medicine composition of the present invention is obtained B;
S4. need to be again with being cooked by slow fire 15-30 minutes to the water decoction A in S3, then high heat decoction 50-90 minutes obtains auxiliary Help the Chinese medicine composition for the treatment of gynecologic malignant tumor.
It is preferred that, Traditional Chinese drug mixture monarch drug in a prescription, ministerial drug, the adjutant in S3 are placed in container and soaked 1-5 hours, normal pressure is decocted After 40-90 minutes, decoction is filtered out, the water extract C of Chinese medicine composition of the present invention is obtained, adds dextrin and Icing Sugar to mix after concentration, With appropriate 70-75% ethanol softwood, cross No. 1 standard compendial sieve and meet the medicine sieve series grain of the R40/3 series of national standard, 35-55 DEG C dry 1-4 hours, and dry particle crosses 12~14 mesh sieve whole grains, packing, obtains the particle of the Chinese medicine composition of the present invention Agent.
It is preferred that, Traditional Chinese drug mixture monarch drug in a prescription, ministerial drug, the adjutant in S3 are placed in container and soaked 1-4 hours, normal pressure is decocted After 40-90 minutes, decoction is filtered out, the water extract of Chinese medicine composition of the present invention is obtained, plus microcrystalline cellulose and starch are mixed, plus Enter appropriate 70-75% ethanol softwood, cross No. 1 standard compendial sieve and meet the medicine sieve series grain of the R40/3 series of national standard, 35-55 DEG C dry 1-5 hours, and dry particle crosses 12~14 mesh sieve whole grains, adds magnesium stearate, mixing, tabletting obtain the present invention Chinese medicine composition tablet.
The present invention is directed to the gynecologic malignant tumor interpretation of the cause, onset and process of an illness, using supplementing qi and nourishing yin, clearing heat and detoxicating, right supporting anticancer principle of reatment, Traditional Chinese medicine composition is raw materials used inexpensive, Small side effects, can long-term taking.Through clinical application for many years and observation analysis, in this Drug composition improves patients ' life quality, delays recurrence and patient survival to have preferably to auxiliary treatment gynecologic malignant tumor Clinical efficacy.In view of gynecologic malignant tumor morbidity crowd quantity is big, and patient's poor life quality, the state of an illness after operation, chemicotherapy Easily recurrence, therefore the Chinese medicine composition that the present invention is provided has a good application prospect.
Function for raw materials of traditional Chinese medicinal materials of the present invention and effect below:The tuber of pinellia has dissolving lump and resolving mass, its pungent, hardship of the tuber of pinellia;It is pungent Tool walks the property of string, there is diverging, promoting the circulation of qi, promoting circulation of blood effect;Its hardship can remove heat by catharsis.Therefore available for the stagnation of the circulation of vital energy caused by kind of reason, phlegm coagulates, blood stasis etc. Card, the dilute alcohol and infusion or its polysaccharide component, alkaloid of the tuber of pinellia have wide antitumor action.Notopterygium root has dispersing wind and cold It is wet, analgesic efficacy,《Essentials of Materia Medica》:" purging the liver of pathogenic fire gas, searches liver wind, controls evils of wind and weness blended to attack the body, and this is through headache, and governor vessel is disease, and ridge is strong and faints, The soft convulsion of tonic convulsion, aphasia from apoplexy, head rotation hot eyes.”
Traditional Chinese medicine thinks disease of the gynecologic malignant tumor for weakened body resistance malicious Sheng, and chemotherapeutics is right while killing tumor cell The healthy tendency of human body also has very big injury, especially injures larger to spleen and stomach function, causes stomach Qi upward reversal, nausea and vomiting;While by In pain, heavier cause patient is greatly alarmed.Therefore invigoration spleen qi, anti-vomiting, dissolving blood stasis and detoxication, tranquillizing the mind by relieving convulsion are worked as in treatment.The present invention Using spina date seed strengthening the spleen and replenishing qi, the red sage root is promoting blood circulation and removing blood stasis, rhizoma zingiberis, reticulate millettia strengthening spleen and nourishing blood, and windproof, root of Chinese trichosanthes, radix glycyrrhizae are used to detoxify Disappear carbuncle, Radix Angelicae Sinensis, the Radix Astragali be used for tonifying Qi, promoting blood circulation and detoxication, notopterygium root, wilsonii promoting qi circulation and relieving pain, the bighead atractylodes rhizome, evodia rutaecarpa strengthening the spleen and stomach are relieving convulsion Preventing or arresting vomiting, with blood clam and stomach, removing toxic substances.Combine from creating the tuber of pinellia unlike existing traditional Chinese medicine auxiliary treatment means with RADIX ACONITI LATERALIS PREPARATA Use, tuber of pinellia eliminating dampnessization is turbid, normalizing the stomach by guiding QI downward, matching with monkshood can help monkshood to dispel the wet turbid heresy of cold sensation of the genitalia.The two phase 5 both middle benefit gas Turbid eliminating dampness, normalizing the stomach by guiding QI downward are changed in cold dispelling again, and the first YANG deficiency for the treatment of, cold-evil's internal resistance, the card of the wet turbid upper criminal of cold sensation of the genitalia bring out the best in each other, in addition, The effect of notopterygium root is dissipated is added while solving chemotherapy patients' appetite not to spina date seed, evodia rutaecarpa, bighead atractylodes rhizome strengthening the spleen and stomach Shake, body weary powerless, poor life quality the problem of.
Brief description of the drawings
Fig. 1:Volunteer's service condition in example six.
Embodiment
The present invention is made with reference to specific embodiment further to explain.
Embodiment one
A kind of Chinese medicine composition of auxiliary treatment gynecologic malignant tumor proposed by the present invention, includes the original of following parts by weight Material:5 parts of RADIX ACONITI LATERALIS PREPARATA, 10 parts of Radix Angelicae Sinensis, 5 parts of fructus amomi, 10 parts of Poria cocos, 15 parts of the bighead atractylodes rhizome, 15 parts of radix glycyrrhizae, 10 parts of jujube, raw 10 parts of the Radix Astragali, 10 parts of Radix Codonopsis, 10 parts of root of Chinese trichosanthes, 15 parts of coix seed, 15 parts of hairyvein agrimony, 15 parts of reticulate millettia, 10 parts of pig Poria cocos, 5 parts of the red sage root, radix scrophulariae 5 parts, 10 parts of oldenlandia diffusa, 5 parts of folium isatidis, 10 parts of radix glehniae, 10 parts of subprostrate sophora, 10 parts of evodia rutaecarpa, 10 parts of Chinese cassia tree, rhizoma zingiberis 10 parts, 5 parts of ginseng, 8 parts of wilsonii, 10 parts of the tuber of pinellia, 5 parts of fructus amomi, 5 parts of Divine Comedy, 5 parts of the membrane of a chicken's gizzard, windproof 5 parts, 5 parts of sealwort, acid 5 parts of 10 parts of jujube kernel, 5 parts of Sculellaria barbata, 5 parts of turtle shell, 5 parts of ganoderma lucidum, 5 parts of Fructus Aurantii, 10 parts of blood clam and notopterygium root.
A kind of preparation method of the Chinese medicine composition of auxiliary treatment gynecologic malignant tumor, comprises the following steps:By Chinese medicine group Compound is rinsed after being soaked more than 2 hours in container with water, after normal pressure is decocted 30 minutes, is filtered out decoction, is obtained Chinese medicine of the present invention The water decoction of composition.
Embodiment two
A kind of Chinese medicine composition of auxiliary treatment gynecologic malignant tumor proposed by the present invention, includes the original of following parts by weight Material:10 parts of RADIX ACONITI LATERALIS PREPARATA, 12 parts of Radix Angelicae Sinensis, 10 parts of fructus amomi, 12 parts of Poria cocos, 12 parts of the bighead atractylodes rhizome, 12 parts of radix glycyrrhizae, 12 parts of jujube, the raw Radix Astragali 12 Part, 12 parts of Radix Codonopsis, 12 parts of root of Chinese trichosanthes, 15 parts of coix seed, 15 parts of hairyvein agrimony, 15 parts of reticulate millettia, 12 parts of pig Poria cocos, 8 parts of the red sage root, 8 parts of radix scrophulariae, 12 parts of oldenlandia diffusa, 8 parts of folium isatidis, 12 parts of radix glehniae, 12 parts of subprostrate sophora, 12 parts of evodia rutaecarpa, 12 parts of Chinese cassia tree, 12 parts of rhizoma zingiberis, 6 parts of ginseng, 9 parts of wilsonii, 12 parts of the tuber of pinellia, 6 parts of fructus amomi, 6 parts of Divine Comedy, 6 parts of the membrane of a chicken's gizzard, windproof 6 parts, sealwort 6 6 parts of part, 12 parts of spina date seed, 6 parts of Sculellaria barbata, 6 parts of turtle shell, 6 parts of ganoderma lucidum, 6 parts of Fructus Aurantii, 12 parts of blood clam and notopterygium root.
A kind of preparation method of the Chinese medicine composition of auxiliary treatment gynecologic malignant tumor, comprises the following steps:By Chinese medicine group Compound is rinsed after being soaked 3 hours in container with water, after normal pressure is decocted 60 minutes, is filtered out decoction, is obtained Chinese traditional medicine composition of the present invention The water extract of thing, adds dextrin and Icing Sugar to mix after concentration, with appropriate 75% ethanol softwood, crosses No. 1 sieve series grain, 45 DEG C of dryings 2 hours, dry particle crossed 14 mesh sieve whole grains, packing, obtains the granule of the Chinese medicine composition of the present invention.
Embodiment three
A kind of Chinese medicine composition of auxiliary treatment gynecologic malignant tumor proposed by the present invention, includes the original of following parts by weight Material:12 parts of RADIX ACONITI LATERALIS PREPARATA, 15 parts of Radix Angelicae Sinensis, 12 parts of fructus amomi, 15 parts of Poria cocos, 15 parts of the bighead atractylodes rhizome, 15 parts of radix glycyrrhizae, 15 parts of jujube, the raw Radix Astragali 15 Part, 15 parts of Radix Codonopsis, 15 parts of root of Chinese trichosanthes, 20 parts of coix seed, 20 parts of hairyvein agrimony, 20 parts of reticulate millettia, 15 parts of pig Poria cocos, 10 parts of the red sage root, 10 parts of radix scrophulariae, 15 parts of oldenlandia diffusa, 10 parts of folium isatidis, 15 parts of radix glehniae, 15 parts of subprostrate sophora, 15 parts of evodia rutaecarpa, 15 parts of Chinese cassia tree, 15 parts of rhizoma zingiberis, 8 parts of ginseng, 8 parts of wilsonii, 15 parts of the tuber of pinellia, 8 parts of fructus amomi, 8 parts of Divine Comedy, 8 parts of the membrane of a chicken's gizzard, windproof 8 parts, sealwort 8 8 parts of part, 15 parts of spina date seed, 8 parts of Sculellaria barbata, 8 parts of turtle shell, 8 parts of ganoderma lucidum, 8 parts of Fructus Aurantii, 15 parts of blood clam and notopterygium root.
A kind of preparation method of the Chinese medicine composition of auxiliary treatment gynecologic malignant tumor, comprises the following steps:By Chinese medicine group Compound is rinsed after being soaked 3 hours in container with water, after normal pressure is decocted 60 minutes, is filtered out decoction, is obtained Chinese traditional medicine composition of the present invention The water extract of thing, plus microcrystalline cellulose and starch are mixed, and add appropriate 75% ethanol softwood, cross No. 1 sieve series grain, 45 DEG C are done Dry 2 hours, dry particle crossed 12 mesh sieve whole grains, added magnesium stearate, mixing, tabletting obtain the Chinese medicine composition of the present invention Tablet.
Example IV
A kind of Chinese medicine composition of auxiliary treatment gynecologic malignant tumor proposed by the present invention, includes the original of following parts by weight Material:20 parts of Radix Angelicae Sinensis, 10 parts of fructus amomi, 15 parts of Poria cocos, 20 parts of the bighead atractylodes rhizome, 20 parts of radix glycyrrhizae, 15 parts of jujube, raw 15 parts of the Radix Astragali, 20 parts of Radix Codonopsis, It is 20 parts of root of Chinese trichosanthes, 30 parts of coix seed, 30 parts of hairyvein agrimony, 30 parts of reticulate millettia, 20 parts of pig Poria cocos, 15 parts of the red sage root, 15 parts of radix scrophulariae, white 30 parts of HERBA HEDYOTIS DIFFUSAE of flower, 20 parts of folium isatidis, 20 parts of radix glehniae, 30 parts of subprostrate sophora, 30 parts of evodia rutaecarpa, 30 parts of Chinese cassia tree, 20 parts of rhizoma zingiberis, people Ginseng 15 parts, 15 parts of wilsonii, 20 parts of the tuber of pinellia, 15 parts of fructus amomi, 15 parts of Divine Comedy, 15 parts of the membrane of a chicken's gizzard, windproof 10 parts, 10 parts of sealwort, acid 10 parts of 30 parts of jujube kernel, 20 parts of Sculellaria barbata, 15 parts of turtle shell, 20 parts of ganoderma lucidum, 10 parts of Fructus Aurantii, 15 parts of blood clam and notopterygium root.
A kind of preparation method of the Chinese medicine composition of auxiliary treatment gynecologic malignant tumor, comprises the following steps:By Chinese medicine group The monarch drug in a prescription of conjunction, ministerial drug, adjutant wherein without ministerial drug RADIX ACONITI LATERALIS PREPARATA mixture be collectively disposed at rinsed in container with water after immersion 3 it is small When more than, normal pressure decoct 45 minutes after, filter out decoction, obtain the water decoction of Chinese medicine composition of the present invention.
Embodiment five
A kind of Chinese medicine composition of auxiliary treatment gynecologic malignant tumor proposed by the present invention, includes the original of following parts by weight Material:15 parts of RADIX ACONITI LATERALIS PREPARATA, 20 parts of Radix Angelicae Sinensis, 10 parts of fructus amomi, 15 parts of Poria cocos, 20 parts of the bighead atractylodes rhizome, 20 parts of radix glycyrrhizae, 15 parts of jujube, the raw Radix Astragali 15 Part, 20 parts of Radix Codonopsis, 20 parts of root of Chinese trichosanthes, 30 parts of coix seed, 30 parts of hairyvein agrimony, 30 parts of reticulate millettia, 20 parts of pig Poria cocos, 15 parts of the red sage root, 15 parts of radix scrophulariae, 30 parts of oldenlandia diffusa, 20 parts of folium isatidis, 20 parts of radix glehniae, 30 parts of subprostrate sophora, 30 parts of evodia rutaecarpa, 30 parts of Chinese cassia tree, 20 parts of rhizoma zingiberis, 15 parts of ginseng, 15 parts of wilsonii, 20 parts of the tuber of pinellia, 15 parts of fructus amomi, 15 parts of Divine Comedy, 15 parts of the membrane of a chicken's gizzard, windproof 10 parts, 10 parts of sealwort, 30 parts of spina date seed, 20 parts of Sculellaria barbata, 15 parts of turtle shell, 20 parts of ganoderma lucidum, 10 parts of Fructus Aurantii, 15 parts of blood clam and notopterygium root 10 Part.
A kind of preparation method of the Chinese medicine composition of auxiliary treatment gynecologic malignant tumor, comprises the following steps Chinese traditional medicine composition Monarch drug in a prescription, ministerial drug, the mixture of adjutant be collectively disposed at after being rinsed in container with water and soak 3 hours, after normal pressure is decocted 45 minutes, filter Go out decoction, obtain the water decoction of Chinese medicine composition of the present invention.
Respectively by preparation method in the embodiment of the present invention one to five, choose Radiotherapy for Gynecologic Malignancy patient 80 and compared To showing that the efficient situation of preparation method draws following result:
Case Embodiment one Embodiment two Embodiment three Example IV Embodiment five
Patient 80 80 80 80 80
Responder 68 66 72 45 78
It is efficient 85.00% 82.50% 90.00% 56.25% 97.50%
Show that the peculiar tuber of pinellia becomes apparent from RADIX ACONITI LATERALIS PREPARATA drug combination therapeutic effect in comparison result, the present invention, better than other Traditional Chinese medicine prescription.
Embodiment six
The classical analysis of cases of the present invention:Radiotherapy for Gynecologic Malignancy patient 100 is chosen, treatment group is randomly divided into and right Each 50 according to group.Treatment group 50,39 ± 4 years old age;Cancer types:Cervical cancer 20,10 cases on endometrial carcinoma, carcinoma of fallopian tube 10, oophoroma 10.Control group 50,38 ± 5 years old age;Cancer types:Cervical cancer 20,10 cases on endometrial carcinoma is defeated Oviduct cancer 10, oophoroma 10.The general information such as two groups of patient ages, cancer types are through statistical analysis, and difference is without statistics Meaning is learned, with comparativity.
Before control group chemotherapy 30 minutes with ondansetron 8mg intravenous injections, continuous injection 5 days, treatment group is in control group On the basis of the Chinese medicine composition water decoction that provides of the oral present invention:Water decoction is made according to conventional Chinese medicine preparation technology, in chemotherapy Take within first 1 day, everyone daily 1 dose, even served 5 days.
Effective 25 for the treatment of group, effective 22, invalid 3, total effective rate 94%;Effective 16 of control group, effective 8, Invalid 26, total effective rate 48%.Two groups of total effective rates are compared, and difference is statistically significant, with comparativity.This is sent out respectively Preparation method in bright embodiment five, following result is drawn through volunteer's service condition in embodiment six:
Comparison result is drawn, the therapeutic effect of the embodiment of the present invention five is obvious, better than other traditional Chinese medicine prescriptions.
The foregoing is only a preferred embodiment of the present invention, but protection scope of the present invention be not limited thereto, Any one skilled in the art the invention discloses technical scope in, technique according to the invention scheme and its Inventive concept is subject to equivalent substitution or change, should all be included within the scope of the present invention.

Claims (10)

1. a kind of Chinese medicine composition of auxiliary treatment gynecologic malignant tumor, it is characterised in that include the raw material of following parts by weight:Half Summer 10-30 part, 10-30 parts of RADIX ACONITI LATERALIS PREPARATA, 10-30 parts of Radix Codonopsis, raw 10-30 parts of the Radix Astragali, 10-30 parts of root of Chinese trichosanthes, hairyvein agrimony 20-50 Part, 20-50 parts of reticulate millettia, 20-50 parts of evodia rutaecarpa, 20-50 parts of Chinese cassia tree, 3-15 parts of notopterygium root, 10-25 parts of the membrane of a chicken's gizzard, Divine Comedy 10-25 Part, 5-20 parts of wilsonii, 10-25 parts of Poria cocos, 10-25 parts of pig Poria cocos, 10-25 parts of Radix Angelicae Sinensis, 10-30 parts of the bighead atractylodes rhizome, radix glycyrrhizae 10-30 Part, 10-25 parts of jujube, 7-15 parts of Fructus Aurantii, 10-30 parts of the red sage root, 10-30 parts of radix scrophulariae, 10-30 parts of folium isatidis, radix glehniae 15-30 Part, 20-50 parts of subprostrate sophora, 10-30 parts of ginseng, 5-20 parts of blood clam, 15-30 parts of rhizoma zingiberis, 15-45 parts of Sculellaria barbata, fructus amomi 15-50 Part, windproof 5-30 parts, 5-35 parts of sealwort, 20-50 parts of spina date seed, 15-50 parts of oldenlandia diffusa, 15-45 parts of turtle shell, coix seed 15-50 parts and 15-45 parts of ganoderma lucidum.
2. a kind of Chinese medicine composition of auxiliary treatment gynecologic malignant tumor according to claim 1, it is characterised in that including with Lower raw material:11-29 parts of the tuber of pinellia, 11-29 parts of RADIX ACONITI LATERALIS PREPARATA, 11-29 parts of Radix Codonopsis, raw 11-29 parts of the Radix Astragali, root of Chinese trichosanthes 11-29 Part, 21-49 parts of hairyvein agrimony, 21-49 parts of reticulate millettia, 21-49 parts of evodia rutaecarpa, 21-49 parts of Chinese cassia tree, 4-14 parts of notopterygium root, the membrane of a chicken's gizzard 11- 24 parts, 11-24 parts of Divine Comedy, 6-19 parts of wilsonii, 11-24 parts of Poria cocos, 11-29 parts of pig Poria cocos, 11-24 parts of Radix Angelicae Sinensis, bighead atractylodes rhizome 11-29 Part, 11-29 parts of radix glycyrrhizae, 11-24 parts of jujube, 8-14 parts of Fructus Aurantii, 11-29 parts of the red sage root, 11-29 parts of radix scrophulariae, 11-29 parts of folium isatidis, 16-29 parts of radix glehniae, 21-49 parts of subprostrate sophora, 11-29 parts of ginseng, 6-19 parts of blood clam, 16-29 parts of rhizoma zingiberis, Sculellaria barbata 16-44 Part, 16-49 parts of fructus amomi, windproof 6-29 parts, 6-34 parts of sealwort, 21-49 parts of spina date seed, 16-49 parts of oldenlandia diffusa, turtle shell 16- 16-44 parts of 44 parts, 16-49 parts of coix seed and ganoderma lucidum.
3. a kind of Chinese medicine composition of auxiliary treatment gynecologic malignant tumor according to claim 1 or claim 2, it is characterised in that bag Include following raw material:12-28 parts of the tuber of pinellia, 12-28 parts of RADIX ACONITI LATERALIS PREPARATA, 12-28 parts of Radix Codonopsis, raw 12-28 parts of the Radix Astragali, root of Chinese trichosanthes 12-28 parts, 22-48 parts of hairyvein agrimony, 22-48 parts of reticulate millettia, 22-48 parts of evodia rutaecarpa, 22-48 parts of Chinese cassia tree, 5-13 parts of notopterygium root, in chicken Golden 12-23 parts, 12-23 parts of Divine Comedy, 7-18 parts of wilsonii, 12-23 parts of Poria cocos, 12-28 parts of pig Poria cocos, 12-23 parts of Radix Angelicae Sinensis, the bighead atractylodes rhizome 12-28 parts, 12-28 parts of radix glycyrrhizae, 12-28 parts of jujube, 9-13 parts of Fructus Aurantii, 12-28 parts of the red sage root, 12-28 parts of radix scrophulariae, folium isatidis 12- 28 parts, 17-28 parts of radix glehniae, 22-48 parts of subprostrate sophora, 12-28 parts of ginseng, 7-18 parts of blood clam, 17-28 parts of rhizoma zingiberis, Sculellaria barbata 17-43 parts, 17-48 parts of fructus amomi, windproof 7-28 parts, 7-33 parts of sealwort, 22-48 parts of spina date seed, 17-48 parts of oldenlandia diffusa, soft-shelled turtle 17-43 parts of 17-48 parts of first, 17-48 parts of coix seed and ganoderma lucidum.
4. a kind of Chinese medicine composition of auxiliary treatment gynecologic malignant tumor according to claim 1 or claim 2, it is characterised in that bag Include following raw material:20 parts of the tuber of pinellia, 15 parts of RADIX ACONITI LATERALIS PREPARATA, 15 parts of Radix Codonopsis, raw 15 parts of the Radix Astragali, 15 parts of root of Chinese trichosanthes, hairyvein agrimony 25 Part, 25 parts of reticulate millettia, 20 parts of evodia rutaecarpa, 20 parts of Chinese cassia tree, 10 parts of notopterygium root, 15 parts of the membrane of a chicken's gizzard, 15 parts of Divine Comedy, 10 parts of wilsonii, Fu 15 parts of Siberian cocklebur, 15 parts of pig Poria cocos, 20 parts of Radix Angelicae Sinensis, 15 parts of the bighead atractylodes rhizome, 15 parts of radix glycyrrhizae, 15 parts of jujube, 10 parts of Fructus Aurantii, 15 parts of the red sage root, radix scrophulariae 15 parts, 15 parts of folium isatidis, 15 parts of radix glehniae, 20 parts of subprostrate sophora, 12 parts of ginseng, 10 parts of blood clam, 15 parts of rhizoma zingiberis, Sculellaria barbata 20 Part, 10 parts of fructus amomi, windproof 10 parts, 10 parts of sealwort, 25 parts of spina date seed, 20 parts of oldenlandia diffusa, 20 parts of turtle shell, 20 parts of coix seed and 20 parts of ganoderma lucidum.
5. a kind of Chinese medicine composition of auxiliary treatment gynecologic malignant tumor according to claim 1, it is characterised in that described group The tuber of pinellia is monarch drug in a prescription, RADIX ACONITI LATERALIS PREPARATA, Radix Codonopsis, the raw Radix Astragali, root of Chinese trichosanthes, hairyvein agrimony, reticulate millettia, evodia rutaecarpa, Chinese cassia tree, notopterygium root, chicken in compound Interior gold, Divine Comedy, wilsonii be ministerial drug, Poria cocos, pig Poria cocos, Radix Angelicae Sinensis, the bighead atractylodes rhizome, radix glycyrrhizae, jujube, Fructus Aurantii, the red sage root, radix scrophulariae, folium isatidis, Radix glehniae, subprostrate sophora, ginseng, blood clam, rhizoma zingiberis, Sculellaria barbata, fructus amomi, windproof, sealwort, spina date seed, oldenlandia diffusa, turtle shell, Coix seed, ganoderma lucidum are combined into adjutant.
6. a kind of Chinese medicine composition of auxiliary treatment gynecologic malignant tumor according to claim 1, it is characterised in that described half Summer and notopterygium root ratio are 2-4:1-8.
7. a kind of Chinese medicine composition of auxiliary treatment gynecologic malignant tumor according to claim 1, it is characterised in that the thorn Slender acanthopanax is with being 1.5-3.5 with the ratio of notopterygium root:1-3.
8. a kind of Chinese medicine composition of auxiliary treatment gynecologic malignant tumor, its feature according to any one of claim 1-7 It is, its preparation method comprises the following steps:
S1. claim 1 Chinese medicine is prepared:Notopterygium root picks impurity, cleans, runs through, and cuts into slices, dries;Turtle shell takes Carapax Trionycis (processed), by sand Soil puts heating in iron pan, loose to sandy soil, is put into net turtle shell and fries slightly yellow to epidermis, taking-up weeds out sandy soil, is put into vinegar basin slightly Leaching 10-30 minute, take out dry Carapax Trionycis (processed);RADIX ACONITI LATERALIS PREPARATA is cut into slices, with sand scald to heave and it is micro- discoloration it is stand-by;
S2. it is cooked by slow fire 8-30 minutes in S1, the monarch drug in a prescription tuber of pinellia is first put into, adds the notopterygium root prepared in S1, turtle shell, makes attached Son, is cooked by slow fire after 5-15 minutes and decoction is mixed with adjutant;
S3. the Chinese medicine prepared in S1-S2 and adjutant are collectively disposed at into container to soak 3-5 hours, normal pressure is decocted 20-60 minutes Afterwards, decoction is filtered out, obtaining the water decoction A and mixture B adjutants of Chinese medicine composition of the present invention, to be collectively disposed at immersion 1-3 in container small When more than, normal pressure decoct 10-50 minutes after, filter out decoction, obtain the water decoction A and mixture B of Chinese medicine composition of the present invention;
S4. need to be again with being cooked by slow fire 15-30 minutes to the water decoction A in S3, then high heat decoction 50-90 minutes obtains auxiliary and controlled Treat the Chinese medicine composition of gynecologic malignant tumor.
9. a kind of Chinese medicine composition of auxiliary treatment gynecologic malignant tumor according to claim 8, it is characterised in that by S3 Traditional Chinese drug mixture monarch drug in a prescription, ministerial drug, adjutant be placed in immersion 1-5 hour in container, after normal pressure decoction 40-90 minutes, filter out decoction, The water extract C of Chinese medicine composition of the present invention is obtained, adds dextrin and Icing Sugar to mix after concentration, it is soft with appropriate 70-75% ethanol systems Material, crosses No. 1 standard compendial sieve and meets the medicine sieve series grain of the R40/3 series of national standard, 35-55 DEG C dry 1-4 hours, dries Particle crosses 12~14 mesh sieve whole grains, packing, obtains the granule of the Chinese medicine composition of the present invention.
10. a kind of Chinese medicine composition of auxiliary treatment gynecologic malignant tumor according to claim 8, it is characterised in that by S3 In Traditional Chinese drug mixture monarch drug in a prescription, ministerial drug, adjutant be placed in immersion 1-4 hour in container, after normal pressure decoction 40-90 minutes, filter out medicine Liquid, obtains the water extract of Chinese medicine composition of the present invention, plus microcrystalline cellulose and starch are mixed, and add appropriate 70-75% ethanol Softwood processed, crosses No. 1 standard compendial sieve and meets the medicine sieve series grain of the R40/3 series of national standard, 35-55 DEG C is dry 1-5 hours, Dry particle crosses 12~14 mesh sieve whole grains, adds magnesium stearate, mixing, tabletting obtain the tablet of the Chinese medicine composition of the present invention.
CN201710318927.3A 2017-05-08 2017-05-08 A kind of Chinese medicine composition of auxiliary treatment gynecologic malignant tumor Pending CN107184926A (en)

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Publication number Priority date Publication date Assignee Title
CN112755135A (en) * 2021-02-18 2021-05-07 顾景辉 Traditional Chinese medicine composition for treating HPV (human papilloma Virus) persistent infection and application

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CN105617335A (en) * 2016-02-18 2016-06-01 方瑞艳 Radix bupleurum Xianxiong decoction capable of improving bile reflux gastritis after cancer chemoradiotherapy
CN105748914A (en) * 2016-03-17 2016-07-13 高嵘 Traditional Chinese medicine composition for assisting in treatment of nausea and vomiting after chemotherapy of gynecologic malignant tumor
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* Cited by examiner, † Cited by third party
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