CN107184641A - A kind of gynecological antimicrobial gel recipe and preparation method thereof - Google Patents
A kind of gynecological antimicrobial gel recipe and preparation method thereof Download PDFInfo
- Publication number
- CN107184641A CN107184641A CN201710367444.2A CN201710367444A CN107184641A CN 107184641 A CN107184641 A CN 107184641A CN 201710367444 A CN201710367444 A CN 201710367444A CN 107184641 A CN107184641 A CN 107184641A
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- parts
- glycerine
- chitosan
- kuh
- seng
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/489—Sophora, e.g. necklacepod or mamani
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
- A61K31/722—Chitin, chitosan
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Molecular Biology (AREA)
- Inorganic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention discloses a kind of gynecological antimicrobial gel recipe and preparation method thereof, formula is：20 30 parts of chitosan, 26 parts of kuh-seng, 8 14 parts of sodium alginate, 30 40 parts of glycerine, 10 18 parts of glycerine, 0.5 2 parts of menthol, 6 10 parts of glacial acetic acid, 600 800 parts of purified water；The present invention uses chitosan for primary raw material, harmless, and antibacterial, bactericidal effect are obvious, and preparation technology is simple, easy to use, is adapted to the various gynecological diseases of women and uses.
Description
Technical field
The present invention relates to field of pharmaceutical chemistry technology, specifically a kind of gynecological antimicrobial gel recipe and its preparation
Method.
Background technology
Gynaecological imflammation, including vaginitis, cervicitis etc., it is due to outer damage or infection, causes pathogen bacteria to be attacked
Formed by inflammation.Gynaecological imflammation is the class common disease for perplexing vast female patient, if carrying out treatment not in time will have
The state of an illness may be increased, serious consequence is caused.
Treatment for gynaecological imflammation class is mainly administered by local, removes or kill pathogen, recovers normal micro-
Environment, repairs damaged tissues, so as to reach curative effect.Current gynecologic medicine is a lot, has the cleaning fluid of cleaning, there is oral
Capsule etc., its using effect is all undesirable, and bactericidal effect is not obvious, and gynecological disease cannot be controlled effectively, suffers to women
Person brings the trouble of many.
Chitosan has antibacterial, antitumor, the function such as enhancing is immune, with good biocompatibility, and nonirritant,
Have no toxic side effect, chitosan gel rubber treatment bacterial vaginosis, candida albicans bacterium property vaginal disease, trichomonas vaginal disease,
There is preferable therapeutic action in terms of the gynecological diseases such as cervical erosion.
The content of the invention
It is reasonable in design, make in view of the defects and deficiencies of the prior art, the present invention intends to provide one kind is simple in construction
With convenient gynecological antimicrobial gel recipe and preparation method thereof, chitosan is used for primary raw material, it is harmless, antibacterial, kill
Bacterium effect is obvious, and preparation technology is simple.
To achieve the above object, the technical solution adopted by the present invention is：
A kind of gynaecologic antibiotic gel, is formulated as follows：
A kind of preparation method of gynaecologic antibiotic gel is：
1st, weighing for raw material is carried out according to formula；
2nd, glacial acetic acid, glycerine, menthol are separately added into chitosan, is stirred, it is completely molten to chitosan
Solution, it is standby；
3rd, a small amount of purified water is taken to soak kuh-seng 10 minutes, then heating is carried out after decocting 30 minutes, is cooled down simultaneously
Kuh-seng water is made in impurity screening, standby；
4th, sodium alginate, purified water, kuh-seng water are sequentially added in standby raw material, is stirred；
5th, glycerine is eventually adding, is slowly stirred, gel is formed.
After said structure, beneficial effects of the present invention are：Chitosan is used for primary raw material, it is harmless, resist
Bacterium, bactericidal effect are obvious, and preparation technology is simple, easy to use, are adapted to the various gynecological diseases of women and use.
Embodiment
In order to make the purpose , technical scheme and advantage of the present invention be clearer, it is right below in conjunction with embodiment
The present invention is further elaborated.It should be appreciated that embodiment described herein is only to explain the present invention, and
It is not used in the restriction present invention.
Embodiment 1：
A kind of gynaecologic antibiotic gel, is formulated as follows：
A kind of preparation method of gynaecologic antibiotic gel is：
1st, weighing for raw material is carried out according to formula；
2nd, glacial acetic acid, glycerine, menthol are separately added into chitosan, is stirred, it is completely molten to chitosan
Solution, it is standby；
3rd, a small amount of purified water is taken to soak kuh-seng 10 minutes, then heating is carried out after decocting 30 minutes, is cooled down simultaneously
Kuh-seng water is made in impurity screening, standby；
4th, sodium alginate, purified water, kuh-seng water are sequentially added in standby raw material, is stirred；
5th, glycerine is eventually adding, is slowly stirred, gel is formed.
Embodiment 2：
A kind of gynaecologic antibiotic gel, is formulated as follows：
Embodiment 3：
A kind of gynaecologic antibiotic gel, is formulated as follows：
It is obvious to a person skilled in the art that the invention is not restricted to the details of above-mentioned one exemplary embodiment, Er Qie
In the case of without departing substantially from spirit or essential attributes of the invention, the present invention can be realized in other specific forms.Therefore, no matter
From the point of view of which point, embodiment all should be regarded as exemplary, and be nonrestrictive, the scope of the present invention is by appended power
Profit is required rather than described above is limited, it is intended that all in the implication and scope of the equivalency of claim by falling
Change is included in the present invention.
Moreover, it will be appreciated that although the present specification is described in terms of embodiments, not each embodiment is only wrapped
Containing an independent technical scheme, this narrating mode of specification is only that for clarity, those skilled in the art should
Using specification as an entirety, the technical solutions in the various embodiments may also be suitably combined, forms those skilled in the art
It may be appreciated other embodiment.
Claims (5)
1. a kind of gynaecologic antibiotic gel, it is characterised in that：Formula is：20-30 parts of chitosan, 2-6 parts of kuh-seng, sodium alginate 8-14
Part, 30-40 parts of glycerine, 10-18 parts of glycerine, 0.5-2 parts of menthol, 6-10 parts of glacial acetic acid, 600-800 parts of purified water.
2. a kind of gynaecologic antibiotic gel according to claim 1, it is characterised in that：Formula is：20 parts of chitosan, kuh-seng 2
Part, 8 parts of sodium alginate, 30 parts of glycerine, 10 parts of glycerine, 0.5 part of menthol, 6 parts of glacial acetic acid, 600 parts of purified water.
3. a kind of gynaecologic antibiotic gel according to claim 1, it is characterised in that formula is：30 parts of chitosan, kuh-seng 6
Part, 14 parts of sodium alginate, 40 parts of glycerine, 18 parts of glycerine, 2 parts of menthol, 10 parts of glacial acetic acid, 800 parts of purified water.
4. a kind of gynaecologic antibiotic gel according to claim 1, it is characterised in that formula is：15 parts of chitosan, kuh-seng 4
Part, 11 parts of sodium alginate, 35 parts of glycerine, 14 parts of glycerine, 1 part of menthol, 8 parts of glacial acetic acid, 700 parts of purified water.
5. a kind of preparation method of gynaecologic antibiotic gel, it is characterised in that：Step is as follows：
(1), weighing for raw material is carried out according to formula；
(2) glacial acetic acid, glycerine, menthol, are separately added into chitosan, is stirred, is completely dissolved to chitosan,
It is standby；
(3) a small amount of purified water, is taken to soak kuh-seng 10 minutes, then heating is carried out after decocting 30 minutes, is cooled down and mistake
Filter impurity and kuh-seng water is made, it is standby；
(4) sodium alginate, purified water, kuh-seng water, are sequentially added in standby raw material, is stirred；
(5) glycerine, is eventually adding, is slowly stirred, gel is formed.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710367444.2A CN107184641A (en) | 2017-05-23 | 2017-05-23 | A kind of gynecological antimicrobial gel recipe and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710367444.2A CN107184641A (en) | 2017-05-23 | 2017-05-23 | A kind of gynecological antimicrobial gel recipe and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
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| CN107184641A true CN107184641A (en) | 2017-09-22 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201710367444.2A Pending CN107184641A (en) | 2017-05-23 | 2017-05-23 | A kind of gynecological antimicrobial gel recipe and preparation method thereof |
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| Country | Link |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108524923A (en) * | 2018-07-11 | 2018-09-14 | 江苏万可瑞科技实业有限公司 | A kind of gynaecologic antibiotic gel and its production method |
| CN114129592A (en) * | 2021-12-06 | 2022-03-04 | 郑州大学第一附属医院 | Disinfection gel for obstetrics and gynecology department and preparation method thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102626524A (en) * | 2012-05-04 | 2012-08-08 | 江西中兴汉方药业有限公司 | Chitosan gynaecologic antibacterial gel and preparation method thereof |
| CN106039394A (en) * | 2016-06-02 | 2016-10-26 | 四川奎星医用高分子制品有限责任公司 | Medical composite chitosan gel containing antibacterial drug |
-
2017
- 2017-05-23 CN CN201710367444.2A patent/CN107184641A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102626524A (en) * | 2012-05-04 | 2012-08-08 | 江西中兴汉方药业有限公司 | Chitosan gynaecologic antibacterial gel and preparation method thereof |
| CN106039394A (en) * | 2016-06-02 | 2016-10-26 | 四川奎星医用高分子制品有限责任公司 | Medical composite chitosan gel containing antibacterial drug |
Non-Patent Citations (1)
| Title |
|---|
| 王薇等: "复方苦参壳聚糖凝胶剂的制备与临床应用", 《中国药师》 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108524923A (en) * | 2018-07-11 | 2018-09-14 | 江苏万可瑞科技实业有限公司 | A kind of gynaecologic antibiotic gel and its production method |
| CN114129592A (en) * | 2021-12-06 | 2022-03-04 | 郑州大学第一附属医院 | Disinfection gel for obstetrics and gynecology department and preparation method thereof |
| CN114129592B (en) * | 2021-12-06 | 2023-03-10 | 郑州大学第一附属医院 | Disinfecting gel for obstetrics and gynecology department and preparation method thereof |
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| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20170922 |
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