CN107173669A - A kind of mineral substance mycotoxin takes off mould dose and preparation method thereof - Google Patents
A kind of mineral substance mycotoxin takes off mould dose and preparation method thereof Download PDFInfo
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- CN107173669A CN107173669A CN201710528267.1A CN201710528267A CN107173669A CN 107173669 A CN107173669 A CN 107173669A CN 201710528267 A CN201710528267 A CN 201710528267A CN 107173669 A CN107173669 A CN 107173669A
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L5/00—Preparation or treatment of foods or foodstuffs, in general; Food or foodstuffs obtained thereby; Materials therefor
- A23L5/20—Removal of unwanted matter, e.g. deodorisation or detoxification
- A23L5/27—Removal of unwanted matter, e.g. deodorisation or detoxification by chemical treatment, by adsorption or by absorption
- A23L5/273—Removal of unwanted matter, e.g. deodorisation or detoxification by chemical treatment, by adsorption or by absorption using adsorption or absorption agents, resins, synthetic polymers, or ion exchangers
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/174—Vitamins
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/20—Inorganic substances, e.g. oligoelements
- A23K20/22—Compounds of alkali metals
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/20—Inorganic substances, e.g. oligoelements
- A23K20/30—Oligoelements
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Abstract
Mould dose and preparation method thereof is taken off the present invention relates to a kind of mineral substance mycotoxin, it is characterised in that the components by weight percent of the de- mould dose raw material includes：Modified montmorillonite used 60% 70%, modified galapectite 10% 20%, tourmaline 5% 15%, vitamin 5% and mineral matter 5%.The efficient absorption to mycotoxin and selective absorption can be achieved by being combined to modified montmorillonite used and modified galapectite in the preparation method, i.e., while efficient absorption mycotoxin, adsorbs little to various nutriments；The addition of tourmaline can reduce the surface tension of water, promote animal to absorb nutriment, regulate and control animal body microcirculation, residual of the reduction mycotoxin in animal tissue.
Description
Technical field
Field is removed the present invention relates to mycotoxin adsorption, and in particular to a kind of mineral substance mycotoxin takes off mould dose and its system
Preparation Method.
Background technology
Mycotoxin is the secondary metabolic product of fungi, and it is red that common mycotoxin mainly includes aflatoxin, corn
Mould ketenes, vomitoxin, ochratoxin, fumonisin etc..Mycotoxin almost influences each organ of animal bodies, especially
It is liver, kidney, intestines and stomach, spleen and nervous system, causes animal feed intake to decline, feed conversion rate reduction, animal immunizing power
Reduction, ill probability increase.In addition, many mycotoxins have cumulative effect and chain effect in vivo, by being transferred to poultry
Jeopardize human health in product.
At present, mould method, chemistry mainly are taken off including physics to the de- mould method of feed progress and takes off mould method, biological de- mould method.Thing
Reason, which takes off mould method, includes absorption method, WATER-WASHING METHOD, scalping method, de- embryo detoxification method etc..Chemistry takes off mould method and mainly uses chemical reagent, leads to
Peracid treatment, alkali process or nitrogen treatment, make part toxin lose vigor.It is special that bioanalysis mainly uses certain micro-organisms to decompose
Determine mycotoxin, and then change the structure of lps molecule, reach that degraded removes mycotoxin purpose.These methods are to mycotoxin
There is certain detoxification effect, but still suffer from that the rate of adsorption is slow, adsorption function is single, absorption nutriment, influence feed palatability
The problems such as.It is, thus, sought for a kind of adsorption rate is high, the rate of adsorption is fast, beneficial to storage, feed palatability is not caused damage,
It is again cheap, it is adapted to de- mould dose of mass production.
Publication No. for CN 103521173A patent disclose it is a kind of can in adsorption feed the red ketenes of corn adsorbent
And preparation method thereof, the adsorbent is using galapectite powder as raw material, through surfactant stearyl dimethyl benzyl ammonium chloride
Immersion, is stirred, and is washed, and is filtered, drying, obtained by grind into powder.Although the adsorbent is preferable to the red ketenes adsorption effect of corn,
But its absorbing mycotoxin effect is more single, it is impossible to meet market to de- mould dose multi-functional requirement.
Publication No. discloses the preparation method that a kind of palatability feed takes off mould dose for CN106666334A patent, and this is de- mould
Agent is made up of montmorillonite, julid, chitterlings, hawthorn, Chinese cassia tree, fennel seeds, anise, Chinese prickly ash etc., and its preparation method is that will go first
Seed hawthorn is squeezed the juice, filtered, then montmorillonite is soaked in filtrate, and filtrate is done into freezing processing；Then by julid, chitterlings with it is pre-
Processing montmorillonite is fermented；The progress mixing of the materials such as Chinese cassia tree, fennel seeds is boiled again, it is finally freeze-dried mixed with montmorillonite etc.
To de- mould dose.Although the de- agent can preferably suppress mycotoxin, its operating process complexity is, it is necessary to hawthorn, julid, pig
Small intestine etc. is cleaned repeatedly repeatedly, and the process such as needs to freeze, boils, and cost is higher, and the time is longer；And there is hawthorn, julid, pig
Small intestine cleaning, which is not reduced thoroughly, takes off mould effect, or even causes de- mould dose the problems such as can not use, and is not suitable for mass production.
The content of the invention
In view of the shortcomings of the prior art, the technical problem that the present invention is intended to solve is to provide a kind of mineral substance mycotoxin and taken off
Mould dose and preparation method thereof.The preparation method can be achieved to mould by being combined to modified montmorillonite used and modified galapectite
The efficient absorption of toxin and selective absorption, i.e., while efficient absorption mycotoxin, adsorb little to various nutriments；
The addition of tourmaline can reduce the surface tension of water, promote animal to absorb nutriment, and animal body is micro- follows for regulation and control
Ring, residual of the reduction mycotoxin in animal tissue.
The present invention solves the technical scheme that the technical problem used：
A kind of mineral substance mycotoxin takes off mould dose, it is characterised in that the components by weight percent of the de- mould dose raw material includes：It is modified
Montmorillonite 60%-70%, modified galapectite 10%-20%, tourmaline 5%-15%, vitamin 5% and mineral matter 5%.
The step of a kind of above-mentioned mineral substance mycotoxin takes off mould dose of preparation method, this method be：By tourmaline raw material
Ore grinding, then the circular grinding on homogenizer are first circulated on low-speed mixer, the rotating speed of the low-speed mixer is 2000-
4000r/min, the rotating speed of homogenizer is 14000-18000r/min, obtains the tourmaline powder that particle diameter is 1.0-3.0 μm；
Modified montmorillonite used and modified galapectite is crushed to the mesh of 100 mesh -200 with disk mill respectively；Then by the modification after crushing
Montmorillonite and modified galapectite and tourmaline powder mix each suspension after being made into 2-4% suspension, immersion 16-24h respectively
Close, then magnetic agitation 2-4h centrifuges 10-20min, and dried completely at 80-150 DEG C under 2000-4000r/min rotating speed
Dry, grinding obtains dried mineral powder；Add water, dried mineral powder and vitamin and mineral are carried out fully to mix
Close, drying, sieving produce mineral substance mycotoxin and take off mould dose.
The present invention also protects the feed that a kind of above-mentioned mineral substance mycotoxin of addition takes off mould dose.
Compared with prior art, the beneficial effects of the invention are as follows：
(1) mineral substance mycotoxin of the present invention takes off mould dose using modified montmorillonite used, modified galapectite and tourmaline to be main former
Material, three's synergy, can adsorb a variety of mycotoxins simultaneously in animal intestinal tract, can realize the efficient absorption to mycotoxin
And selective absorption, i.e., while efficient absorption mycotoxin, little are adsorbed to various nutriments, will not be to poultry just
It is frequently grown and impacts.The tourmaline that the present invention is added has the characteristics such as radiation far infrared, spontaneous polarization, it is possible to decrease the surface of water
Tension force, the penetration of raising water, dissolving power, extension, can strengthen poultry immunity of organisms, release and poisoned caused by mycotoxin
Effect, improves poultry health status；Modified montmorillonite used decapacitation increases outside to the adsorbance of mycotoxin, to the bacillary abdomen of poultry
Rush down, the illness such as virus diarrhea, lientery, ulcerative colitis has certain therapeutic effect.
(2) modified montmorillonite used, modified galapectite and tourmaline three are combined by preparation method of the present invention, can effectively go decontamination
Contaminate a variety of mycotoxins (including aflatoxin B in feed1(AFB1), T-2 toxin, zearalenone (ZEN)), solve
The problem of common mold toxin sorbent removes single mycotoxin, inefficiency, in particular improves to Gibberella zeae alkene
The adsorption rate of ketone；Regulate and control the microcirculation of animal using the characteristic of tourmaline simultaneously, be favorably improved the general level of the health of animal.
(3) modified montmorillonite used, modified galapectite and tourmaline are mixed and used by the present invention, can give full play to three
Respective advantage, and mutual inferior position is compensate for, so as to substantially increase to aflatoxin B1It is mould with zearalenone etc.
The adsorption capacity of verticillium toxin.When being used alone modified montmorillonite used, to highly polar mycotoxin adsorption effect such as aspergillus flavus poison
Plain B1Adsorption effect preferably, it is but still undesirable to the adsorption capacity of low pole mycotoxin such as zearalenone；Individually make
The adsorption capacity of zearalenone is improved with modified galapectite, but it is poor to other mycotoxin adsorption effects.The present invention
De- mould dose compared with the additive agent modified montmorillonite of conventional feed or modified galapectite, each component has the work of Synergistic
With can significantly increase the adsorption capacity to mycotoxin, eliminate influence of the mycotoxin to animal physiological, improve animal to disease
Resistance, and the price of deed can be significantly improved.And with high adsorption capacity, the characteristics of adsorption rate is fast can be rapid, significant
The mycotoxin concentration in animal blood and target organ is reduced, taking off the mould dose of stable compound combined to form with mycotoxin can
Excrete, therefore poultry is edible for a long time will not also produce adverse reaction or rely on symptom.
Embodiment
The present invention is expanded on further with reference to embodiment, but not in this, as to the application claims
Restriction.
The components by weight percent for the raw material that mineral substance mycotoxin of the present invention takes off mould dose includes：Modified montmorillonite used 60%-70%, change
Property galapectite 10%-20%, tourmaline 5%-15%, vitamin 5% and mineral matter 5%；
The vitamin is at least one of vitamin C, vitamin E；The mineral matter is zinc methionine and potassium chloride
Mixture.
The step of mineral substance mycotoxin of the present invention takes off mould dose of preparation method, this method be：Tourmaline raw material is first existed
Ore grinding, then the circular grinding on homogenizer are circulated on low-speed mixer, the rotating speed of the low-speed mixer is 2000-
4000r/min, the rotating speed of homogenizer is 14000-18000r/min, obtains the tourmaline powder that particle diameter is 1.0-3.0 μm；
Modified montmorillonite used and modified galapectite is crushed to the mesh of 100 mesh -200 with disk mill respectively；Then by the modification after crushing
Montmorillonite and modified galapectite and tourmaline powder mix each suspension after being made into 2-4% suspension, immersion 16-24h respectively
Close, then magnetic agitation 2-4h centrifuges 10-20min, and dried completely at 80-150 DEG C under 2000-4000r/min rotating speed
Dry, grinding obtains dried mineral powder；Add water, dried mineral powder and vitamin and mineral are carried out fully to mix
Close, drying, sieving produce mineral substance mycotoxin and take off mould dose.
Wherein modified montmorillonite used preparation method is：By montmorillonite stock dispersion in water, the matter of montmorillonite raw material and water
Amount is than being 1:15-25, using magnetic stirring apparatus heating stirring, is warming up to 70-80 DEG C, is stirred for 2-6h；Then hexadecane is added
Base trimethylammonium bromide (CTAB), the quality of cetyl trimethylammonium bromide is the 1/15~1/8 of montmorillonite material quality, after
Continuous stirring 3-5h, then stand 7-10h；Suction filtration is carried out after standing, then with being dried after distillation water washing, crosses 100-200 mesh sieves, obtains
It is modified montmorillonite used；During this this sufficiently time of repose to obtain suction filtration process more modified montmorillonite used；
Described cetyl trimethylammonium bromide is organic surface active agent, when preparing modified montmorillonite used, can be with
Use DTAC, dodecyl benzyl dimethyl ammonium chloride, stearyl dimethyl benzyl ammonium chloride, two
The mixing of one or both of DTAC, double octadecyl methyl benzyl ammonium chlorides any of the above ratio
Thing；
Being modified the preparation method of galapectite is：Galapectite raw material is crushed to 100-200 mesh, galapectite after then crushing
Mixed with the KH-570 in the mixed solvents for sequentially adding second alcohol and water, the galapectite, KH-570 and second alcohol and water it is mixed
The mass ratio of bonding solvent is 20:1:20, the volume ratio of the in the mixed solvent second alcohol and water of second alcohol and water is 3:1, obtain mixing molten
Liquid；Mixed solution pH value is adjusted to 4-5 with hydrochloric acid；After the completion of reaction, the suspension that inclines is centrifuged, according to solid-to-liquid ratio mg：ML=
20：100 distilled water immersion, is repeated 2-4 times, is placed in 80 DEG C of baking ovens and is dried after suction filtration, is crushed, is sieved after cooling, produces and change
Property galapectite.Have during modified galapectite is prepared and crush twice, it is in order that galapectite energy and modifying agent to crush for the first time
More preferably contact, so that reaction is more thorough, modified effect is more preferable；And it is because needing rise temperature in drying course to crush for the second time
Degree, modified galapectite can produce caking in temperature-rise period, so needing to crush again.In this application, with silane coupled
Agent KH-570 is modified to galapectite, be can obtain hydrophobic performance and is preferably modified galapectite.Modified galapectite surface, which is introduced, to be had
Machine functional group, effectively reduces the polarity of galapectite, while improving the dispersive property of modified galapectite.KH-570 (methyl-props
Olefin(e) acid base propyl trimethoxy silicane) be silane coupler one kind.
In preparation method of the present invention select ultra-fine tourmaline particle diameter it is small, can preferably play tourmaline it is radiation infrared,
The characteristics such as spontaneous polarization, and be more easy to be well mixed when being made into suspension；And in modified montmorillonite used and modified galapectite and tourmaline
Centrifugation, drying are had to pass through after powder three mixing, each component is moisture state after centrifugation, and drying temperature is relatively low, and mineral can
It can not dry completely, this will influence de- mould dose using effect；Drying temperature is too high to cause modified montmorillonite used, modified galapectite
Structure change.
The present invention also protects the feed that a kind of above-mentioned mineral substance mycotoxin of addition takes off mould dose.Described mineral substance mould poison
De- mould dose of element is added in complete feed by mass fraction 0.1%-1.0% to be used.In feeding process, keeper is to mineral
Class mycotoxin takes off mould dose of use, can be according to the digestion of animal, absorption, growth time and feedstuff mould contamination feelings
Condition, feed mold degree and storage time take the circumstances into consideration to increase and decrease consumption.
Montmorillonite of the present invention to the absorption of highly polar mycotoxin preferably, but to low pole mycotoxin adsorption performance compared with
Difference.It is organically-modified by being carried out to montmorillonite, the adsorption capacity to low pole mycotoxin can be improved, and can effectively reduce to battalion
Support the suction-operated of material.The present invention is cetyl front three by being modified processing, surfactant used to montmorillonite
Base ammonium bromide (CTAB), it is possible to increase the interlamellar spacing of montmorillonite, and can obtain preferable oleophylic performance, thus improve to it is hydrophobic,
In low polarity mycotoxin adsorption effect.
Galapectite is 1:The aqueous layer silicate mineral of 1 structure, its unique tubular structure, higher specific surface area with
And unique charge characteristics make galapectite have stronger adsorption capacity.There is galapectite excellent absorption to fix work to mycotoxin
With not by mycotoxin itself polarity effect, thus the effect of absorbing mycotoxin is preferable, but it is directly utilized, and it is adsorbed
Effect does not often reach requirement.By being modified processing to galapectite, its uniformity and decentralization can be made substantially to increase, it is easy to
Mixed in feed.Modified galapectite surface-active increase, and increasing with the contact area of mycotoxin, is more beneficial for pair
The absorption of mycotoxin, in particular improves the adsorption capacity to the low pole mycotoxin such as zearalenone, reduces mould
The infringement that verticillium toxin is caused to body.
Tourmaline has excellent thermoelectricity capability, piezoelectric property, spontaneous polarization performance and radiation infrared performance, its spoke
The far infrared penetrated can weaken the hydrogen bond action between hydrone, macromolecular mass water is become small-micelle water, reduce the table of water
Face tension force, so that the solvability of water, penetrating power and diffusivity have all strengthened, can strengthen the work of desmoenzyme
Property, the metabolism of animal is improved, strengthens immunity of organisms；And the operation speed of small-micelle water in animal body can be accelerated
Degree, so that the speed that cell absorbs nutriment is accelerated.In addition, tourmaline contain animal body necessary to potassium, sodium, calcium, magnesium,
The trace element such as the macroelements such as phosphorus and zinc, iron, selenium, copper, iodine, fluorine., can will be normal in tourmaline in animal body under acid environment
Amount and trace element disengage, and are finally absorbed by animal body, so as to promote the metabolism of animal, and animal body is micro- follows for regulation and control
Ring, reduces residual of the mycotoxin in animal tissue.
The present invention is also with the use of vitamins such as vitamin C and vitamin Es.Vitamin C is a kind of important antioxidant,
The lipid components that can be played on protection biomembrane are not oxidized, alleviate the damage that stress be caused to body；Vitamin E can be protected
Shield body tissue is not attacked by lipid free radical, so as to prevent in cell membrane the peroxidating of fat and caused one be therefrom
Row infringement, weakens the activity of superoxide anion and hydrogen peroxide in phagocyte, thus extends the life of cell.
Mineral matter is made up of zinc methionine and potassium chloride, wherein, the organic zinc in zinc methionine is to enhancing animal immune
Power has booster action；Potassium chloride can provide potassium, chlorion, it is ensured that the normal physiological function of animal when mycotoxin is encroached on.
Embodiment 1
The components by weight percent that the present embodiment mineral substance mycotoxin takes off mould dose of raw material includes modified montmorillonite used 60%, modification angstrom
Lip river stone 20%, iron tourmaline 10%, vitamin 5%, mineral matter 5%.The vitamin is the mixing of vitamin C and vitamin E
Thing；The mineral matter is the mixture of zinc methionine and potassium chloride.
The preparation method that the present embodiment mineral substance mycotoxin takes off mould dose is：
(1) modified montmorillonite used preparation：10g montmorillonites are weighed, are scattered in 200ml water, magnetic stirrer, are heated up
To 70-80 DEG C.The cetyl trimethylammonium bromide (CTAB) that 1g is added after a period of time is stirred, continues to stir 4h, stands 8h
Suction filtration, with being dried after distillation water washing, crosses 100 mesh sieves, obtains organically modified montmorillonite clay afterwards.
(2) preparation of modified galapectite：100g galapectites are weighed, 100 mesh are crushed to.By 100g galapectites and 5mg 18
Zephiran is mixed with 100ml distilled water, 50 DEG C of waters bath with thermostatic control, is shaken with 5000r/min speed, reaction
10min.After the completion of reaction, the suspension that inclines is centrifuged, with distilled water immersion, 15min is shaken, this process is repeated 3 times；Suction filtration again
After be placed in dry in 80 DEG C of baking ovens 100 mesh particles be crushed to after 6h, cooling.
(3) de- mould dose preparation：For iron tourmaline mineral, ore grinding is first circulated on low-speed mixer, then at a high speed
Circular grinding on mixer, the rotating speed of the low-speed mixer is 3000r/min, and the rotating speed of homogenizer is 16000r/
Min, it is 2.0 μm to make its particle diameter.By modified montmorillonite used, modified galapectite, the tourmaline after pulverization process be made into respectively 2% it is outstanding
Each suspension is mixed after turbid liquid, immersion 24h, magnetic agitation 2h, 2000r/min centrifugation 10min, 100 DEG C of drying, grinding is obtained
Dried mineral powder；Plus suitable quantity of water, the mineral powder obtained after drying is thoroughly mixed with vitamin, mineral matter, drying,
Sieving, produces mineral substance mycotoxin and takes off mould dose.
Application method：Mineral substance mycotoxin manufactured in the present embodiment is taken off mould dose according to 0.3% ratio (feeding i.e. per ton
Material addition 3Kg mineral substance mycotoxin takes off mould dose) it is added in complete feed.
Embodiment 2
The components by weight percent for the raw material that the present embodiment mineral substance mycotoxin takes off mould dose includes：Modified montmorillonite used 60%, it is modified
Galapectite 15%, iron tourmaline 15%, vitamin 5%, mineral matter 5%.The vitamin is the mixed of vitamin C and vitamin E
Compound；The mineral matter is the mixture of zinc methionine and potassium chloride.
Wherein modified montmorillonite used preparation method is：By montmorillonite stock dispersion in water, the matter of montmorillonite raw material and water
Amount is than being 1:15, using magnetic stirring apparatus heating stirring, 80 DEG C are warming up to, 4h is stirred for；Then cetyl trimethyl is added
Ammonium bromide, the quality of cetyl trimethylammonium bromide is the 1/9 of montmorillonite material quality, continues to stir 4h, then stand 10h；
Suction filtration is carried out after standing, then with being dried after distillation water washing, crosses 100 mesh sieves, obtains modified montmorillonite used；
Being modified the preparation preparation method of galapectite is：Galapectite raw material is crushed to 100 mesh, galapectite after then crushing
Mixed with the KH-570 in the mixed solvents for sequentially adding second alcohol and water, the galapectite, KH-570 and second alcohol and water it is mixed
The mass ratio of bonding solvent is 20:1:20, the volume ratio of the in the mixed solvent second alcohol and water of second alcohol and water is 3:1, obtain mixing molten
Liquid；Mixed solution pH value is adjusted to 4-5 with hydrochloric acid；After the completion of reaction, the suspension that inclines is centrifuged, according to solid-to-liquid ratio mg：ML=
20：100 distilled water immersion, is repeated 2-4 times, is placed in 80 DEG C of baking ovens and is dried after suction filtration, is crushed, is sieved after cooling, produces and change
Property galapectite.
The preparation method that the present embodiment mineral substance mycotoxin takes off mould dose is：Tourmaline raw material is first on low-speed mixer
Ore grinding, then the circular grinding on homogenizer are circulated, the rotating speed of the low-speed mixer is 3000r/min, homogenizer
Rotating speed be 16000r/min, it is 2.0 μm of tourmaline powder to obtain particle diameter；Modified montmorillonite used and modified galapectite is used respectively
Disk mill is crushed to 100 mesh；Then the modified montmorillonite used and modified galapectite and tourmaline powder after crushing are matched somebody with somebody respectively
Into 2% suspension, each suspension is mixed after immersion 24h, then magnetic agitation 2h centrifuges under 2000r/min rotating speed
10min, and dried completely at 100 DEG C, grinding obtains dried mineral powder；Add water, by dried mineral powder with
Vitamin and mineral is sufficiently mixed, and is dried, is sieved, and is produced mineral substance mycotoxin and is taken off mould dose.
Embodiment 3
The components by weight percent for the raw material that the present embodiment mineral substance mycotoxin takes off mould dose includes：Modified montmorillonite used 65%, it is modified
Galapectite 20%, iron tourmaline 5%, vitamin 5%, mineral matter 5%.The vitamin is the mixing of vitamin C and vitamin E
Thing；The mineral matter is the mixture of zinc methionine and potassium chloride.Method of preparation and use be the same as Example 2.
Embodiment 4
The components by weight percent for the raw material that the present embodiment mineral substance mycotoxin takes off mould dose includes：Modified montmorillonite used 65%, it is modified
Galapectite 10%, iron tourmaline 15%, vitamin 5%, mineral matter 5%.The species of vitamin and mineral matter, de- mould dose preparation
And application method be the same as Example 2.
Embodiment 5
The components by weight percent for the raw material that the present embodiment mineral substance mycotoxin takes off mould dose includes：Modified montmorillonite used 70%, it is modified
Galapectite 10%, iron tourmaline 10%, vitamin 5%, mineral matter 5%.The species of vitamin and mineral matter, de- mould dose preparation
And application method be the same as Example 2.
Comparative example 1
De- mould dose of raw material of comparative example 1 is modified montmorillonite used 90%, vitamin 5%, mineral matter 5% are constituted.The dimension
Raw element is vitamin C and the mixture of vitamin E；The mineral matter is the mixture of zinc methionine and potassium chloride.
100 mesh are crushed to disk mill by modified montmorillonite used；Then modified montmorillonite used after crushing is made into 2%
Suspension, soaks 24h, magnetic agitation 2h, 10min is then centrifuged under 2000r/min rotating speed, and dried completely at 100 DEG C
Dry, grinding obtains dried mineral powder；Add water, dried mineral powder and vitamin and mineral are carried out fully to mix
Close, drying, sieving are produced.
Comparative example 2
De- mould dose of raw material of comparative example 2 is to be modified galapectite 90%, vitamin 5%, mineral matter 5% to constitute, by modification
Galapectite is crushed to 100 mesh with disk mill；Then modification galapectite after crushing is made into 2% suspension, is soaked
24h, magnetic agitation 2h, then centrifuge 10min under 2000r/min rotating speed, and are dried completely at 100 DEG C, and grinding is obtained
Dried mineral powder；Add water, dried mineral powder and vitamin and mineral are sufficiently mixed, drying, mistake
Sieve, is produced.
Comparative example 3
De- mould dose of raw material of comparative example 3 is modified montmorillonite used 70%, modified galapectite 20%, vitamin 5%, mineral matter
5% composition, 100 mesh are crushed to disk mill by modified montmorillonite used and modified galapectite；Then by the modified illiteracy after crushing
De- stone and modified galapectite mix each suspension after being made into 2% suspension, immersion 24h, magnetic agitation 2h, Ran Hou
10min is centrifuged under 2000r/min rotating speed, and is dried completely at 100 DEG C, grinding obtains dried mineral powder；Add water,
Dried mineral powder and vitamin and mineral are sufficiently mixed, dries, sieve, produce.
The present invention is mould by modified montmorillonite used, modified galapectite, the compound obtained mineral substance of tourmaline by many experiments practice
Verticillium toxin takes off mould dose, the efficient absorption to mycotoxin and selective absorption can be achieved, i.e., in the same of efficient absorption mycotoxin
When, little are adsorbed to various nutriments.
In laboratory, progress mineral substance mycotoxin of the present invention takes off the mould dose of absorption to mycotoxin and takes off mould effect test.It is real
Test and be divided into 8 groups.1-5 groups are respectively embodiment 1, embodiment 2, embodiment 3, embodiment 4, de- mould dose of embodiment 5,6-8
Group for comparative example 1, comparative example 2, de- mould dose of comparative example 3.
Experiment is aflatoxin B with mycotoxin1(AFB1), T-2 toxin, zearalenone (ZEN).By aspergillus flavus
Toxin B1, T-2 toxin, zearalenone be dissolved in respectively in simulated gastric fluid, 1000ug/L solution is configured to, per 8ml solution
Middle addition feed takes off mould dose of 0.1g, stirs and evenly mixs, stands, 3000r/min centrifugations 10min after 2h, determines mould poison in supernatant
The changes of contents of element, each 3 repetitions of processing, average, and calculate the adsorption rate that feed takes off mould dose.
Measuring result is specifically shown in Table 1.
The adsorption rate (%) of each embodiment of table 1 and comparative example to various mycotoxins
From experimental result, the present invention takes off the mould dose of adsorption rate to aflatoxin B1 more than 92%, red to corn
The adsorption rate of mould ketenes (ZEN) is more than 80%, to T-2 adsorption rate 60% or so；De- mould dose of the present invention is to three kinds of moulds
Toxin adsorption rate is far above de- mould dose or modified montmorillonite used, the modified galapectite that modified montmorillonite used, modified galapectite is used alone
Compound de- mould dose.The two de- mould dose compound adsorption effect has increase relative to a certain kind is used alone, but to yellow bent
Mould toxin B1 adsorption rate is less than 87%, and the adsorption rate to zearalenone (ZEN) is only 66.2%, to T-2 adsorption rate
For 52.3%, this adsorpting data can not still meet requirement of the existing production to feed detoxification.The present invention will it is modified montmorillonite used with
Modified galapectite, tourmaline three are carried out after being combined, and have the result of significant Synergistic in absorbing mycotoxin effect, from table
In it can be seen that its effect rise relative to comparative example it is a lot, it is notable to the adsorption effect of various mycotoxins.It is simultaneously de- mould
Appropriate tourmaline is added in agent to promote animal to absorb nutriment, regulate and control animal body microcirculation, to mould poison
Element poisoning has certain defense reaction.Each embodiment of Comprehensive Correlation and comparative example to the adsorption effect of mycotoxin, embodiment 2,
Embodiment 4, embodiment 5 are preferable to the detoxification efficiency of various mycotoxins.Modified montmorillonite used and modified angstrom prepared in embodiment 2
Lip river stone relative adsorption performance more preferably, can be significantly improved to aflatoxin B1With the adsorption capacity of zearalenone (ZEN).
Zoopery is carried out to embodiment 2,4,5,24d wean, the consistent sodium selenite 36 of body weight, sex (boar) is chosen
Head, is randomly divided into 4 groups, every group of 9 repetitions each repeat 1 pig.Control group and 3 experimental groups are set, and control group, which is fed, not to be added
Plus compound de- mould dose normal diet, 1 group of experiment (taking off mould dose described in addition embodiment 2), 2 groups of experiment are (described in addition embodiment 4
De- mould dose), 3 groups of experiment (taking off mould dose described in addition embodiment 5) feed the feed de- mould dose with the addition of control group equivalent respectively,
Result of the test such as table 2.
A kind of mineral substance mycotoxin of the invention of table 2 takes off the mould dose of influence to Growth Performance of Weaning Piglets
From table 2 this it appears that taking off mould dose to Growth Performance of Weaning Piglets using a kind of mineral substance mycotoxin of the invention
Substantially, the piglet incidence of disease declines action effect, the death rate is reduced, daily gain increase.Wherein to test being averaged for 2 groups of weanling pigs
Preferably, morbidity and mortality are minimum for daily gain, illustrate that the de- mould dose of adsorption effect to mycotoxin of embodiment 4 is best, this
It is due to that the modified montmorillonite used and modified galapectite ratio that embodiment 4 is added is suitable.By modified montmorillonite used, modified galapectite and electricity
Gas stone is combined, and can play a part of Synergistic, can be achieved to adsorb highly polar and low pole mycotoxin synchronous high-efficiency,
Adsorbance increase to mycotoxin, reduces the harm of mycotoxin, while absorption of the animal to nutriment can be promoted sharp
With enhancing immunity of organisms.
The present invention does not address part and is applied to prior art.
Claims (5)
1. a kind of mineral substance mycotoxin takes off mould dose, it is characterised in that the components by weight percent of the de- mould dose raw material includes：It is modified to cover
De- stone 60%-70%, modified galapectite 10%-20%, tourmaline 5%-15%, vitamin 5% and mineral matter 5%.
2. mineral substance mycotoxin according to claim 1 takes off mould dose, it is characterised in that the vitamin be vitamin C,
At least one of vitamin E；The mineral matter is the mixture of zinc methionine and potassium chloride.
3. the step of mineral substance mycotoxin described in a kind of claim 1 or 2 takes off mould dose of preparation method, this method is：Will
Tourmaline raw material first circulates ore grinding, then the circular grinding on homogenizer on low-speed mixer, the low-speed mixer
Rotating speed is 2000-4000r/min, and the rotating speed of homogenizer is 14000-18000r/min, and it is 1.0-3.0 μm to obtain particle diameter
Tourmaline powder；Modified montmorillonite used and modified galapectite is crushed to the mesh of 100 mesh -200 with disk mill respectively；Then by powder
Modified montmorillonite used and modified galapectite and tourmaline powder after broken are made into respectively will after 2-4% suspension, immersion 16-24h
Then each suspension mixing, magnetic agitation 2-4h centrifuges 10-20min under 2000-4000r/min rotating speed, and in 80-150
Dried completely at DEG C, grinding obtains dried mineral powder；Add water, by dried mineral powder and vitamin and mineral
It is sufficiently mixed, dries, sieves, is produced mineral substance mycotoxin and take off mould dose.
4. mineral substance mycotoxin according to claim 3 takes off mould dose of preparation method, it is characterised in that：
Modified montmorillonite used preparation method is：By montmorillonite stock dispersion in water, the mass ratio of montmorillonite raw material and water is 1:
15-25, using magnetic stirring apparatus heating stirring, is warming up to 70-80 DEG C, is stirred for 2-6h；Then cetyl trimethyl is added
Ammonium bromide, the quality of cetyl trimethylammonium bromide is the 1/15 ~ 1/8 of montmorillonite material quality, continues to stir 3-5h, then quiet
Put 7-10h；Suction filtration is carried out after standing, then with being dried after distillation water washing, crosses 100-200 mesh sieves, obtains modified montmorillonite used；
Being modified the preparation preparation method of galapectite is：Galapectite raw material is crushed to 100-200 mesh, galapectite after then crushing
Mixed with the KH-570 in the mixed solvents for sequentially adding second alcohol and water, the galapectite, KH-570 and second alcohol and water it is mixed
The mass ratio of bonding solvent is 20:1:20, the volume ratio of the in the mixed solvent second alcohol and water of second alcohol and water is 3:1, obtain mixing molten
Liquid；Mixed solution pH value is adjusted to 4-5 with hydrochloric acid；After the completion of reaction, the suspension that inclines is centrifuged, according to solid-to-liquid ratio mg：mL=
20 ：100 distilled water immersion, is repeated 2-4 times, is placed in 80 DEG C of baking ovens and is dried after suction filtration, is crushed, is sieved after cooling, produces and change
Property galapectite.
5. a kind of feed, it is characterised in that the feed takes off mould added with any described mineral substance mycotoxins of claim 1-4
Agent.
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| CN109362965A (en) * | 2018-10-29 | 2019-02-22 | 安徽绿迪食品股份有限公司 | A kind of wild boar fattening nutrient fodder |
| CN109497307A (en) * | 2018-10-29 | 2019-03-22 | 安徽绿迪食品股份有限公司 | A kind of reduction wild boar disease incidence nutrient fodder |
| CN112515037A (en) * | 2020-12-01 | 2021-03-19 | 河北普农文化传播有限公司 | Enzyme for livestock and poultry mould removal |
| CN115137035A (en) * | 2022-07-14 | 2022-10-04 | 浙江维精科技有限公司 | Preparation method of montmorillonite mildew preventive |
| CN115428857A (en) * | 2021-06-03 | 2022-12-06 | 菲吉乐科(中国)生物科技有限公司 | Broad-spectrum mildew removing agent and processing technology and application thereof |
| CN115428885A (en) * | 2021-06-02 | 2022-12-06 | 菲吉乐科(南京)生物科技有限公司 | Broad-spectrum mildew removing agent capable of simultaneously adsorbing mycotoxin, endotoxin and enterotoxin |
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Application publication date: 20170919 |