CN107164221A - The device of electromagnetic force heating damage spin dialysis cancer cells in blood - Google Patents
The device of electromagnetic force heating damage spin dialysis cancer cells in blood Download PDFInfo
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- CN107164221A CN107164221A CN201710309953.XA CN201710309953A CN107164221A CN 107164221 A CN107164221 A CN 107164221A CN 201710309953 A CN201710309953 A CN 201710309953A CN 107164221 A CN107164221 A CN 107164221A
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Abstract
The device of electromagnetic force heating damage spin dialysis cancer cells in blood, belong to medical imaging technology field, by dialysis rotating cylinder (1), filter collection organelle (2), enter blood vessel (3), go out blood vessel (4), enter blood vessel head (5), bleeding tube head (6), vortex generator (7), control panel (8), general supply line plug (13), general supply line (14), pedestal (36), filter collection organelle power bus (37) constitute, it is characterised in that：Described dialysis rotating cylinder (1) is cylindric, side wall lower edge is fixed on pedestal (36), in the longitudinally disposed 4 12 row filter collection organelle (2) of dialysis rotating cylinder (1) side wall inner surfaces, controlled panel (8) control；Pedestal (36) cast iron matter, center is embedded with vortex generator (7), and top is provided with control panel (8), and upper surface sealing is fixed with dialysis rotating cylinder (1).The device makes simple, and workable, with low cost, effect is obvious.
Description
Technical field
The present invention relates to the device of electromagnetic force heating damage spin dialysis cancer cells in blood, belong to medical imaging technology
Field.
Background technology
Tumour (tumor, neoplasm) is a kind of genopathy, but is not hereditary.It refers to cell in tumorigenesis factor
Under effect, gene is changed, and is lost the normal regulation grown to it, is caused paraplasm.It can be divided into benign and malignant swollen
The major class of knurl two.The former is slow-growing, with surrounding tissue boundary clear, does not shift, little to human health damage.The latter gives birth to
It is long rapid, other body parts are can be transferred to, harmful substance can be also produced, normal organ structure is destroyed, body function is lacked of proper care,
Life-threatening.Tumor tissues are made up of essence and interstitial two parts, and tumor epithelial cell is tumour cell, are the main components of tumour,
With tissue-derived specificity.It determines the Biological characteristics of tumour and the particularity of every kind of tumour.Generally according to tumour
Substantive form recognizes the tissue-derived of various tumours, carries out classification, name and the histodiagnosis of tumour, and according to its differentiation
Maturity and atypia size determine the grade malignancy of the good pernicious and tumour of tumour.Tumour cell has three significant bases
Eigen is：Immortality, migration and loses contact inhibition.In addition, tumour cell also has many different from normal cell
Physiology, biochemical and morphological feature.Cancer cell size and form differs, generally bigger than its source cell volume, fast growth,
Nucleocytoplasmic ratio is significantly higher than normal cell, and up to 1: 1, normal noble cells nucleocytoplasmic ratio is only 1: 4-6.Nuclear morphology differs, and can
There is macronucleus, double-core or many nuclear phenomena.Chromosome is in non-multiple state (aneuploidy), some chromosome deficiencies in core, and has
A little chromosome number increases.The abnormal change of normal cell chromosome, meeting active cell apoptotic process, but in cancer cell,
The related signal path of Apoptosis produces obstacle, that is to say, that cancer cell has immortality.With migration, cell adhesion and
The related composition (such as ECM, CAM) of connection is morphed or lacked, and associated signal paths are obstructed, and cell loses with iuntercellular and carefully
Connection between extracellular matrix, it is easy to come off from tumour.Many cancer cells have an amoeboid movement ability, and can produce enzyme,
Make blood vessel basement layer and connective tissue perforation, make it to other tissue migrations.Malignant epithelial cell tumour is also cancer
(cancer) it is the current class disease for endangering human health most serious.In the U.S., the death rate of malignant tumour is only second to painstaking effort
Pipe disease and occupy second.According to China's Development of Health Service situation statistical communique in 2000, urban area Residents death cause first
Secondly it is cerebrovascular disease, heart disease for malignant tumour.The most commonly seen and serious tumour of harmfulness is lung cancer, nasopharyngeal carcinoma, oesophagus
Cancer, stomach cancer, colorectal cancer, liver cancer, breast cancer, cervical carcinoma, leukaemia and lymthoma etc..Known ability is conventional wisdom is that in pre-cancer, such as
Fruit, which checks, to come and patient is carried out the treatment such as to perform the operation, and cancer can be cured, once but cancer metastasis, rethink and cure just
It is relatively difficult, although some medicines have lethal effect to cancer cell, 1,000 are fought the enemy from damaging 800, patient often controls again
Body and mind is wrecked by very big during treatment, and final does not break away from death still to destiny.If can be by the cancer cell of transfer
Separate and kill or damage, under the cooperation of medicine, the life of patient is then expected to be extended.The transfer of cancer cell is often
By the transport of blood, and spherical state is typically presented in the cancer cell for leaving surface, therefore how to divide cancer cell from blood
Separate out and carry out and damaged a great problem as being badly in need of solving, so, by way of dialysis, blood samples of patients is pumped into and dialysed
Rotating cylinder, then forms vortex by vortex generator in dialysis rotating cylinder, and under the influence of centrifugal force, nucleocytoplasmic ratio is big, volume
Larger cancer cell will be centrifuged to swirl edge, and the seizure of organelle is collected by filter, you can cancer cell is gathered in into filter collection
In organelle abdomen, meanwhile, after the electromagnetic force heating damage device of filter collection organelle is powered, spiral electromagnetic force heat production coil can
Higher temperature is formed, the cancer cell that damage needle point effect is in contact with it is heated by electromagnetic force, so as to scald or scald that to ruin cancer thin
Born of the same parents, reach the purpose of damage cancer cell, and aggregation cancer cell invents a kind of electromagnetic force heating damage spin dialysis cancer cells in blood
Device be necessary.
The content of the invention
In order to overcome the problem that cancer cell is separated and damaged from blood, the invention provides electromagnetic force plus
Heat waste ruins the device of spin dialysis cancer cells in blood, the device of this kind of electromagnetic force heating damage spin dialysis cancer cells in blood
By way of dialysis, blood samples of patients is pumped into dialysis rotating cylinder, then vortex is formed in dialysis rotating cylinder by vortex generator,
Under the influence of centrifugal force, nucleocytoplasmic ratio is big, also larger cancer cell will be centrifuged to swirl edge to volume, collect cell by filter
The seizure of device, you can cancer cell is gathered in filter collection organelle abdomen, meanwhile, the electromagnetic force heating damage device of filter collection organelle leads to
After electricity, spiral electromagnetic force heat production coil can form higher temperature, pass through electromagnetic force heating damage needle point effect and its
The cancer cell of contact, ruins cancer cell so as to scald or scald, reaches the purpose of damage cancer cell.
The technical solution adopted for the present invention to solve the technical problems is：
The device of electromagnetic force heating damage spin dialysis cancer cells in blood of the present invention, by dialysis rotating cylinder 1, filter collection cell
Device 2, enter blood vessel 3, go out blood vessel 4, enter blood vessel first 5, bleeding tube head 6, vortex generator 7, control panel 8, general supply line plug 13,
General supply line 14, pedestal 36, filter collection organelle power bus 37 are constituted, it is characterised in that：The described glass of dialysis rotating cylinder 1
Matter, cylindrical shape, intracavity diameter are 5-20 centimetres, are highly 10-30 centimetres, and wall thickness is 0.5-1 centimetres, and upper underseal is closed, bottom
Opening, side wall lower edge is fixed on pedestal 36, from being provided with side wall lower edge total height 2/3 into blood vessel first 5, is entered blood vessel first 5 and is justified
Tubular, interior diameter be 0.3-0.6 centimetres, overall diameter be 0.5-0.8 centimetres, one end connection dialysis rotating cylinder 1, the other end connect into
The chamber of blood vessel 3；From being provided with bleeding tube head 6 at side wall lower edge total height 1/4, the cylindrical shape of bleeding tube head 6, interior diameter is 0.3-0.6
Centimetre, overall diameter is 0.5-0.8 centimetres, and one end connection dialysis rotating cylinder 1, the other end connects out the chamber of blood vessel 4；In dialysis rotating cylinder
The longitudinally disposed 4-12 row filter collection organelle 2 of 1 side wall inner surfaces, each column is provided with 10-20 filter collection organelle 2, and each filter collection is thin
Born of the same parents' device 2 has a filter collection organelle power line 12, and each column filter collection organelle 2 has a filter collection organelle power bus 37,
Filter collection organelle power line 12 is in parallel with filter collection organelle power bus 37, and filter collection organelle 37 26S Proteasome Structure and Functions of power bus are same
Known bifilar copper core power line, copper core is a diameter of 0.5-3 millimeters, and controlled panel 8 is controlled；The cast iron matter of pedestal 36, cuboid
Shape, length is 20-30 centimetres, and width is 20-30 centimetres, is highly 10-20 centimetres, center is embedded with vortex generator 7, and top is set
Control panel 8 is equipped with, upper surface sealing is fixed with dialysis rotating cylinder 1.
The described plastics matter of filter collection organelle 2, tulwar sheath shape is arranged in rows on the inner surface of the dialysis wall of rotating cylinder 1, by
Filter collection organelle power line 12, electromagnetic force heating damage device 20, normal cell filter opening 21, filter collection organelle fixing bolt 22, filter
Collect organelle fixed plate 23, filter collection organelle mouthful 24, filter collection organelle chin 25, filter collection organelle neck 26, filter collection organelle chamber
27th, filter collection organelle abdomen 28, filter collection organelle point 29 are constituted；Filter collection organelle power line 12 is known bifilar copper core power supply
Line, copper core is a diameter of 8-20 microns, and one end is connected in parallel filter collection organelle power bus 37, and the other end is connected in parallel electromagnetic force and added
Heat waste ruins device 20；Normal cell filter opening 21 is the circular hole that is distributed on the filter collection wall of organelle 2, a diameter of 5-8 microns, and its size can be with
According to the big minor adjustment of specific processing cancer cell；The 26S Proteasome Structure and Function of filter collection organelle fixing bolt 22 is stainless with known bolt
Steel；Filter collection organelle fixed plate 23 is that the filter collection side wall of organelle 2 does not have the part of normal cell filter opening 21, with dialysis rotating cylinder
1 wall is fitted；Filter collection organelle mouthful 24 is the opening of filter collection organelle 2, and the direction come towards vortex is circular, and a diameter of 8-15 is micro-
Rice；Filter collection organelle chin 25 is expanding for filter collection 24 rears of organelle mouthful, there is normal cell filter opening 21 on wall；Filter collection organelle
Neck 26 is the curved elongated passageway being upwardly formed of filter collection organelle chin 25；Filter collection organelle chamber 27 is the inner chamber of filter collection organelle 2；
Filter collection organelle abdomen 28 is that filter collection organelle 2 rear portion contains cancer cell, filters the part of normal plasma cell, and top sets multiple electricity
Magnetic force heating damage device 20；Filter collection organelle point 29 is the rear end sharp parts of filter collection organelle abdomen 28, does not have normal cell filter opening
21 and electromagnetic force heating damage device 20, be that cancer cell is assembled to form a core.
Described vortex generator 7 is arranged on the center of haemodialysis rotating cylinder 1, by spiral vortex tooth 15, motor power-supply wire 16,
Motor 17, motor power-supply wire plug 18 and spiral vortex axle 19 are constituted；The manganese steel matter of spiral vortex axle 19, cylinder, a diameter of 1-5 lis
Rice, is highly 5-10 centimetres, and the rotor of one end and motor 17 is linked to be an entirety, another end dissociative, in haemodialysis rotation
The surface of 1 part of cylinder is provided with spiral spiral vortex tooth 15；The manganese steel matter of spiral vortex tooth 15, is the superficial-helical of spiral vortex axle 19
Projection, height of projection be 1-3 centimetres, base thickness be 0.5-0.8 centimetres, dissociate edge thickness be 0.1-0.2 centimetres；Motor electricity
Source line 16 is known bifilar copper core power line, and copper core is a diameter of 5-10 millimeters, one end connection motor 17, other end connection electricity
Electromechanical source line plug 18；Motor 17 is known motor 17.
Described enters a diameter of 0.5-0.8 centimetres of blood vessel 3, and 0.05-1 millimeters of wall thickness, material and function are transfused blood with known
Pipe, one end is connected with syringe needle, and other end connection, which is located on the dialysis side wall of rotating cylinder 1, enters blood vessel first 5；Go out blood vessel 4 a diameter of
0.5-0.8 centimetres, 0.05-1 millimeters of wall thickness, material and function are with known blood transfusion tube, and one end connection is located at dialysis rotating cylinder 1 side
Bleeding tube head 6 on wall, the other end is connected with syringe needle；Control panel 8 is arranged on pedestal with the control panel on known electrical equipment
36 top, including master switch 9, control display lamp 10 and control display board 11；Master switch 9 is that electromagnetic force heating damage rotation is saturating
Analyse the power switch of the device of cancer cells in blood；Display lamp 10 is controlled with known indicator lamp, the core with controlling display board 11
Piece is connected；Control display board 11 is that known LCDs and its connected chip are constituted；General supply line plug 13 is with public
Three power-line plugs known；General supply line 14 is known bifilar copper core power line, and copper core is a diameter of 8-20 millimeters, and one end connects
Connect the device of electromagnetic force heating damage spin dialysis cancer cells in blood, other end connection general supply line plug 13.
Described electromagnetic force heating damage device more than 20, each electromagnetic force heating damage device 20 is by electromagnetic force heating damage pin
Point 30, electromagnetic force heat production coil 31, electromagnetic force heating damage needle handle 32, electromagnetic force heating damage device pedestal 33, electromagnetic force heating
Damage device power-line plug 34 and electromagnetic force heating damage device power line 35 are constituted, and are being arranged on the top of filter collection organelle abdomen 28 just
It is miniature electromagnetic force heater, after energization, spiral electromagnetic force heat production coil 31 can be formed at normal cell filter opening 21
Higher temperature, heats damage needle point 30 by electromagnetic force and acts on the cancer cell being in contact with it, cancer cell is ruined so as to scald or scald,
Reach the purpose of damage cancer cell；Electromagnetic force heating damage needle point 30 is that electromagnetic force heating damage device 20 exposes to filter collection organelle
The part in direction in chamber 27, stainless steel is coniform, and basal diameter is 0.1-0.5 microns, is highly 0.1-0.5 microns, with it
The electromagnetic force heating damage needle handle 32 of base portion is collectively forming the axis of electromagnetic force heat production coil 31, but not with electromagnetic force heat production coil
31 contacts, ruin so as to scald or scald cancer cell；The electromagnetic force heating damage stainless steel of needle handle 32, cylindric, a diameter of 0.1-
0.5 micron, base portion is fixed on electromagnetic force heating damage device pedestal 33；Electromagnetic force heat production coil 31 is copper, and cross section is circular, directly
Footpath is 0.1-0.5 microns, and helical arrangement is in the outside of electromagnetic force heating damage needle handle 32, not with electromagnetic force heating damage needle handle 32
Contact, produces heat, heating electromagnetic power heating damage needle point 30 and the electromagnetic force heating damage common shape of needle handle 32 during for being powered
Into axis；The rubber mass of electromagnetic force heating damage device pedestal 33, cylinder is a diameter of 1-5 microns, is fixed with electromagnetic force heating damage
Needle handle 32 and electromagnetic force heating damage device power line 35 are ruined, and electromagnetic force heat production coil 31 is wrapped up, it is ensured that only electromagnetic force adds
Heat waste ruins needle point 30 and is exposed to direction in filter collection organelle chamber 27；Electromagnetic force heating damage device power-line plug 34 is electromagnetic force heating
The tie point that damage device power line 35 is connected with filter collection organelle power line 12, ensure that the two connects together；Electromagnetic force adds
It is the wire that electric power is provided for electromagnetic force heat production coil 31 that heat waste, which ruins device power line 35, and 26S Proteasome Structure and Function is with known bifilar copper core
Power line, copper core cross section is circular, a diameter of 0.1-0.5 microns.
Beneficial effects of the present invention are that the device of electromagnetic force heating damage spin dialysis cancer cells in blood passes through dialysis
Mode, by blood samples of patients be pumped into dialysis rotating cylinder, then by vortex generator dialysis rotating cylinder form vortex, in centrifugal force
In the presence of, nucleocytoplasmic ratio is big, also larger cancer cell will be centrifuged to swirl edge to volume, collect catching for organelle by filter
Catch, you can cancer cell is gathered in filter collection organelle abdomen, meanwhile, after the electromagnetic force heating damage device of filter collection organelle is powered,
Spiral electromagnetic force heat production coil can form higher temperature, heat what damage needle point effect was in contact with it by electromagnetic force
Cancer cell, ruins cancer cell so as to scald or scald, reaches the purpose of damage cancer cell.In electromagnetic force heating damage spin dialysis blood
The device equipment therefor of cancer cell makes simple, and workable, with low cost, effect is obvious.
Brief description of the drawings
The present invention is further described below in conjunction with the accompanying drawings.
Fig. 1 is the overall structure diagram for the device that electromagnetic force of the present invention heats damage spin dialysis cancer cells in blood.
Fig. 2 is that the vortex generator structure for the device that electromagnetic force of the present invention heats damage spin dialysis cancer cells in blood is shown
It is intended to.
Fig. 3 is that the filter collection organelle structure for the device that electromagnetic force of the present invention heats damage spin dialysis cancer cells in blood shows
It is intended to.
Fig. 4 is the electromagnetic force heating damage device for the device that electromagnetic force of the present invention heats damage spin dialysis cancer cells in blood
Structural representation.
1. dialysis rotating cylinder in figure, 2. filter collection organelles, 3. enter blood vessel, and 4. go out blood vessel, and 5. enter blood vessel head, and 6. go out blood vessel
Head, 7. vortex generators, 8. control panels, 9. master switch, 10. control display lamps, 11. control display boards, 12. filter collection organelles
Power line, 13. general supply line plugs, 14. general supply lines, 15. spiral vortex teeth, 16. motor power-supply wires, 17. motor, 18. electricity
Electromechanical source line plug, 19. spiral vortex axles, 20. electromagnetic forces heating damage device, 21. normal cell filter openings, 22. filter collection organelles are consolidated
Determine bolt, 23. filters collect organelle fixed plates, and 24. filter Ji Xibaoqikou, 25. filter collection organelle chins, 26. filters collect organelle necks,
27. filter collection organelle chamber, 28. filter collection organelle abdomens, 29. filter collection organelle points, 30. electromagnetic forces heating damage needle point, 31. electromagnetism
Power heat production coil, 32. electromagnetic forces heating damage needle handle, 33. electromagnetic forces heating damage device pedestal, 34. electromagnetic forces heating damage device
Power-line plug, 35. electromagnetic forces heating damage device power line, 36. pedestals, 37. filter collection organelle power bus.
Embodiment
Embodiment one：
As illustrated, the device of the electromagnetic force heating damage spin dialysis cancer cells in blood of the present invention, is rotated by dialysis
Cylinder 1, filter collection organelle 2, enter blood vessel 3, go out blood vessel 4, enter blood vessel first 5, it is bleeding tube head 6, vortex generator 7, control panel 8, total
Switch 9, control display lamp 10, control display board 11, filter collection organelle power line 12, general supply line plug 13, general supply line 14,
Spiral vortex tooth 15, motor power-supply wire 16, motor 17, motor power-supply wire plug 18, spiral vortex axle 19, electromagnetic force heating damage device
20th, normal cell filter opening 21, filter collection organelle fixing bolt 22, filter collection organelle fixed plate 23, filter collection organelle mouthful 24, filter collection
Organelle chin 25, filter collection organelle neck 26, filter collection organelle chamber 27, filter collection organelle abdomen 28, filter collection organelle point 29, electromagnetism
Power heating damage needle point 30, electromagnetic force heat production coil 31, electromagnetic force heating damage needle handle 32, electromagnetic force heating damage device pedestal
33rd, electromagnetic force heating damage device power-line plug 34, electromagnetic force heating damage device power line 35, pedestal 36, filter collection organelle electricity
Source bus 37 is constituted.Dialysis rotating cylinder 1 nature of glass, cylindrical shape, intracavity diameter is 5-20 centimetres, is highly 10-30 centimetres, wall thickness
Spend for 0.5-1 centimetres, upper underseal is closed, bottom is open, and side wall lower edge is fixed on pedestal 36, at side wall lower edge total height 2/3
It is provided with into blood vessel first 5, enters first 5 cylindrical shape of blood vessel, interior diameter is 0.3-0.6 centimetres, and overall diameter is 0.5-0.8 centimetres, is used for
Fix and connect into blood vessel 3, one end connection dialysis rotating cylinder 1, the other end is connected into the chamber of blood vessel 3；From side wall lower edge total height 1/4
Place is provided with bleeding tube head 6, the cylindrical shape of bleeding tube head 6, and interior diameter is 0.3-0.6 centimetres, and overall diameter is 0.5-0.8 centimetres, is used
In fixing and connecting out blood vessel 4, one end connection dialysis rotating cylinder 1, the other end connects out the chamber of blood vessel 4；In the dialysis side wall of rotating cylinder 1
The longitudinally disposed 4-12 row filter collection organelle 2 of inner surface, each column is provided with 10-20 filter collection organelle 2, each filter collection organelle 2
There is a filter collection organelle power line 12, each column filter collection organelle 2 has a filter collection organelle power bus 37, and filter collection is thin
Born of the same parents' device power line 12 is in parallel with filter collection organelle power bus 37, and the 26S Proteasome Structure and Function of filter collection organelle power bus 37 is with known
Bifilar copper core power line, copper core is a diameter of 0.5-3 millimeters, and controlled panel 8 is controlled, during energization, and coupled control is shown
Lamp 10 can be bright；Open after master switch 9, blood is entered in dialysis rotating cylinder 1 up to dialysis rotating cylinder 1 by entering blood vessel 3 through entering blood vessel first 5
During one half volume, vortex generator 7 is started working, and the blood in dialysis rotating cylinder 1 is stirred and is rotated, and then in dialysis rotation
Vortex shape is formed in rotating cylinder 1, vortex generator 7 can make the uppermost edge of blood formation vortex be right up to dialysis rotating cylinder 1
Side wall apical margin, because the nucleocytoplasmic ratio of cancer cell is larger, therefore is typically in outer most edge and most apical margin in rotary course, had been vortexed
Cell in Cheng Zhong, the blood of outer most edge is brought into filter collection organelle 2, the less normal cell of diameter from filter collection organelle mouthful 24
Filtered out from normal cell filter opening 21, the cancer cell being relatively large in diameter then is trapped within filter collection organelle 2, is heated and is damaged by electromagnetic force
Device 20 produce heat treatment and damage, finally reach retention processing cancer cell purpose.The cast iron matter of pedestal 36, cuboid is long
Spend for 20-30 centimetres, width is 20-30 centimetres, is highly 10-20 centimetres, center is embedded with vortex generator 7, and top is provided with
Control panel 8, upper surface sealing is fixed with dialysis rotating cylinder 1, thin for damaging cancer in spin dialysis blood for electromagnetic force heating
The device of born of the same parents provides stability, and during in order to avoid the motor 17 of vortex generator 7 working, whole device is rocked.Enter blood vessel 3 a diameter of
0.5-0.8 centimetres, 0.05-1 millimeters of wall thickness, material and function are with known blood transfusion tube, and one end is connected with syringe needle, suffers from for extracting
The blood of person, other end connection, which is located on the dialysis side wall of rotating cylinder 1, enters blood vessel first 5, and blood can be transported to dialysis rotation
In cylinder 1.Go out a diameter of 0.5-0.8 centimetres of blood vessel 4,0.05-1 millimeters of wall thickness, material and the function blood transfusion tube with known to, one end company
The logical bleeding tube head 6 being located on the dialysis side wall of rotating cylinder 1, the other end is connected with syringe needle, for will locate in haemodialysis rotating cylinder 1
Blood after reason is transmitted back in patient's body.Vortex generator 7 is arranged on the center of haemodialysis rotating cylinder 1, by spiral vortex tooth 15, electricity
Electromechanical source line 16, motor 17, motor power-supply wire plug 18 and spiral vortex axle 19 are constituted, and are the bands in the presence of motor 17
Dynamic spiral vortex axle 19 is rotated, and the spiral vortex tooth 15 of the perficial helical shape of spiral vortex axle 19, which is driven in haemodialysis rotating cylinder 1, to be rotated simultaneously
Vortex is formed in haemodialysis rotating cylinder 1 so that the cell of different quality is separated, outmost cell is that quality is maximum
Cell.The manganese steel matter of spiral vortex axle 19, cylinder, a diameter of 1-5 centimetres, be highly 5-10 centimetres, and one end turns with motor 17
Son is linked to be an entirety, and another end dissociative is provided with spiral spiral vortex tooth on the surface of the part of haemodialysis rotating cylinder 1
15.The manganese steel matter of spiral vortex tooth 15, is the projection of the superficial-helical of spiral vortex axle 19, and height of projection is 1-3 centimetres, and base portion is thick, thick
Spend for 0.5-0.8 centimetres, free edge is thin, thickness is 0.1-0.2 centimetres.Motor power-supply wire 16 is known bifilar copper core power supply
Line, copper core is a diameter of 5-10 millimeters, one end connection motor 17, and other end connection motor power-supply wire plug 18 can be by the external world
Electric energy introduces motor 17.Motor 17 is known motor 17, after the insertion external power receptacle of motor power-supply wire plug 18,
When motor power-supply wire 16 provides electric power, rotor, which is rotated, drives spiral vortex axle 19 to rotate, so as to be formed in haemodialysis rotating cylinder 1
Vortex, so as to centrifugal blood, make in blood due to the larger cancer cell of the larger quality of nucleocytoplasmic ratio be thrown to vortex outer most edge and
Most upper limb and enter in filter collection organelle 2, after the completion of dialysis, the rotor of motor 17, which is rotated, reversely drives spiral vortex axle 19 to rotate,
The vortex in direction is formed so that cancer cell is carried over filter collection organelle 2, to clean filter collection organelle 2.Control panel 8 is with public
The control panel on electrical equipment known, is arranged on the top of pedestal 36, including master switch 9, control display lamp 10 and control display board
11.Master switch 9 is whole electromagnetism after the power switch of the device of electromagnetic force heating damage spin dialysis cancer cells in blood, opening
The device of power heating damage spin dialysis cancer cells in blood can enter working condition.Display lamp 10 is controlled with known instruction
Lamp, with control display board 11 chip be connected, in correlation function implementation procedure can bright light, prompting operating personnel entirely fill at present
It is equipped with which function is being performed.Control display board 11 is that known LCDs and its connected chip are constituted, can
Specific data value is shown, is controlled so that operating personnel are adjusted, such as rotating speed of the rotor of motor 17 etc..General supply line plug 13
With known three power-line plugs, extraneous electric power can be introduced general supply line 14.General supply line 14 is known bifilar copper
Core power line, copper core is a diameter of 8-20 millimeters, the device of one end connection electromagnetic force heating damage spin dialysis cancer cells in blood,
Other end connection general supply line plug 13, can introduce extraneous electric energy electromagnetic force heating damage spin dialysis cancer cells in blood
Device.The filter collection plastics matter of organelle 2, tulwar sheath shape is arranged in rows on the inner surface of the dialysis wall of rotating cylinder 1, thin by filter collection
Born of the same parents' device power line 12, electromagnetic force heating damage device 20, normal cell filter opening 21, filter collection organelle fixing bolt 22, filter collection cell
Device fixed plate 23, filter collection organelle mouthful 24, filter collection organelle chin 25, filter collection organelle neck 26, filter collection organelle chamber 27, filter collection
Organelle abdomen 28, filter collection organelle point 29 are constituted, and can filter out the haemocyte of normal volume, the larger cancer of collected volume is thin
Born of the same parents, make it remain in the filter collection organelle chamber 27 of filter collection organelle abdomen 28, and by the electromagnetic force heating damage thermostimulation of device 20
And it is destroyed.Filter collection organelle power line 12 is known bifilar copper core power line, and copper core is a diameter of 8-20 microns, and one end is in parallel
Connection filter collection organelle power bus 37, the other end is connected in parallel electromagnetic force heating damage device 20, can introduce extraneous electric energy
Electromagnetic force heating damage device 20.Normal cell filter opening 21 is the circular hole being distributed on the filter collection wall of organelle 2, a diameter of 5-8 microns, its
Size can ensure that normal plasma cell is spilt out of hole according to the big minor adjustment of specific processing cancer cell, and red blood cell can be with
Directly spilt out of hole, be due to that diameter is more than filter collection organelle mouthfuls 24 and less enters filter although leucocyte is relatively large in diameter
Collect organelle 2, and it is free after shape is rounded, volume is larger cancer cell can not by and be trapped within filter collection organelle 2, reach
The purpose of cancer cell is filtered to the limit.The 26S Proteasome Structure and Function of filter collection organelle fixing bolt 22 is with known bolt, stainless steel
Matter, for filter collection organelle 2 to be fixed on into the dialysis wall of rotating cylinder 1.Filter collection organelle fixed plate 23 is the filter collection side wall of organelle 2
There is no the part of normal cell filter opening 21, fit filter collection organelle 2 being securely fixed in dialysis with the dialysis wall of rotating cylinder 1
On the wall of rotating cylinder 1.Filter collection organelle mouthful 24 is the opening of filter collection organelle 2, and the direction come towards vortex enters to be vortexed blood
Filter collection organelle 2, it is circular, it is a diameter of 8-15 microns, enter to prevent normal cells such as the bigger leucocyte of volume, phagocytes.
Filter collection organelle chin 25 is expanding for filter collection 24 rears of organelle mouthful, has more normal cell filter opening 21 on wall, to enter
The normal plasma cell of filter collection organelle chamber 27 is filtered out from normal cell filter opening 21 in time, it is impossible to which the cancer cell filtered is then
Filter collection organelle neck 26 is moved up into the presence of the strength such as vortex centrifugal power.Filter collection organelle neck 26 is that filter collects under organelle
The curved elongated passageway being upwardly formed of bar 25, the larger cancer cell of volume is to enter filter collection organelle chamber below in the case where vortex is promoted
In 27.Filter collection organelle chamber 27 is the inner chamber of filter collection organelle 2, is that can contain cancer cell and carry out electrothermal treatment to cancer cell
Space.Filter collection organelle abdomen 28 is that filter collection organelle 2 rear portion contains cancer cell, filters the part of normal plasma cell, and top is set
Multiple electromagnetic force heating damage devices 20 are put, cancer cell are damaged to carry out electric heating stimulation to the cancer cell of collection.Filter collection is thin
Born of the same parents' device point 29 is the rear end sharp parts of filter collection organelle abdomen 28, without normal cell filter opening 21 and electromagnetic force heating damage device 20,
Assemble to form a core for cancer cell.Electromagnetic force heating damage device more than 20, each electromagnetic force heating damage device 20 is by electromagnetism
Power heating damage needle point 30, electromagnetic force heat production coil 31, electromagnetic force heating damage needle handle 32, electromagnetic force heating damage device pedestal
33rd, electromagnetic force heating damage device power-line plug 34 and electromagnetic force heating damage device power line 35 are constituted, and are arranged on filter collection cell
It is miniature electromagnetic force heater at the normal cell filter opening 21 at the top of device abdomen 28, after energization, spiral electromagnetic force heat production
Coil 31 can form higher temperature, and heating damage needle point 30 by electromagnetic force acts on the cancer cell being in contact with it, so as to scald
Wound or the boiling hot purpose ruined cancer cell, reach damage cancer cell.Electromagnetic force heating damage needle point 30 is electromagnetic force heating damage device 20
The part in direction in filter collection organelle chamber 27 is exposed to, stainless steel is coniform, and basal diameter is 0.1-0.5 microns, is highly
0.1-0.5 microns, the axis of electromagnetic force heat production coil 31 is collectively forming with the electromagnetic force heating damage needle handle 32 of its base portion, but not
Contact, ruined so as to scald or scald cancer cell with electromagnetic force heat production coil 31.The electromagnetic force heating damage stainless steel of needle handle 32, circle
Column, a diameter of 0.1-0.5 microns, base portion is fixed on electromagnetic force heating damage device pedestal 33.The bronze medal of electromagnetic force heat production coil 31
Matter, cross section is circular, a diameter of 0.1-0.5 microns, and helical arrangement is in the outside of electromagnetic force heating damage needle handle 32, not with electromagnetism
Power heating damage needle handle 32 is contacted, and heat, heating electromagnetic power heating damage needle point 30 and electromagnetic force heating are produced during for being powered
The axis that damage needle handle 32 is collectively forming.The rubber mass of electromagnetic force heating damage device pedestal 33, cylinder is a diameter of 1-5 microns, Gu
Surely there are electromagnetic force heating damage needle handle 32 and electromagnetic force heating damage device power line 35, and electromagnetic force heat production coil 31 wrapped up,
Ensure that only having electromagnetic force heating damage needle point 30 is exposed to direction in filter collection organelle chamber 27.Electromagnetic force heating damage device power line is inserted
First 34 be the tie point that electromagnetic force heating damage device power line 35 is connected with filter collection organelle power line 12, ensure that the two connects
Together.Electromagnetic force heating damage device power line 35 is the wire that electric power is provided for electromagnetic force heat production coil 31,26S Proteasome Structure and Function
With known bifilar copper core power line, copper core cross section is circular, a diameter of 0.1-0.5 microns.
The general principle and principal character and advantages of the present invention of the present invention has been shown and described above.The technology of the industry
Personnel are it will be appreciated that the present invention is not limited to the above embodiments, and described in above-described embodiment and specification is to illustrate this hair
Bright principle, without departing from the spirit and scope of the present invention, various changes and modifications of the present invention are possible, these changes
It all fall within the protetion scope of the claimed invention with improvement, its is equivalent by appended claims for the claimed scope of the invention
Thing is defined.
Claims (5)
1. electromagnetic force heating damage spin dialysis cancer cells in blood device, by dialysis rotating cylinder (1), filter collection organelle (2),
Enter blood vessel (3), go out blood vessel (4), enter blood vessel head (5), bleeding tube head (6), vortex generator (7), control panel (8), general supply
Line plug (13), general supply line (14), pedestal (36), filter collection organelle power bus (37) composition, it is characterised in that：Described
Dialysis rotating cylinder (1) nature of glass, cylindrical shape, intracavity diameter is 5-20 centimetres, is highly 10-30 centimetres, and wall thickness is 0.5-1 lis
Rice, upper underseal closed, and bottom is open, and side wall lower edge is fixed on pedestal (36), from being provided with side wall lower edge total height 2/3 into blood
Tube head (5), enters blood vessel head (5) cylindrical shape, and interior diameter is 0.3-0.6 centimetres, and overall diameter is 0.5-0.8 centimetres, and one end connection is saturating
Rotating cylinder (1) is analysed, the other end is connected into blood vessel (3) chamber；From being provided with bleeding tube head (6), bleeding at side wall lower edge total height 1/4
Tube head (6) cylindrical shape, interior diameter is 0.3-0.6 centimetres, and overall diameter is 0.5-0.8 centimetres, one end connection dialysis rotating cylinder (1),
The other end connects out blood vessel (4) chamber；Collect organelle (2) in the longitudinally disposed 4-12 row filter of dialysis rotating cylinder (1) side wall inner surfaces, often
Row are provided with 10-20 filter collection organelle (2), and each filter collection organelle (2) has a filter collection organelle power line (12), often
Row filter collection organelle (2) has a filter collection organelle power bus (37), filter collection organelle power line (12) and filter collection cell
Device power bus (37) is in parallel, and filter collection organelle power bus (37) 26S Proteasome Structure and Function is with known bifilar copper core power line, copper
Core diameter is 0.5-3 millimeters, controlled panel (8) control；Pedestal (36) cast iron matter, cuboid, length is 20-30 centimetres,
Width is 20-30 centimetres, is highly 10-20 centimetres, center is embedded with vortex generator (7), top is provided with control panel (8),
Upper surface sealing is fixed with dialysis rotating cylinder (1).
2. the device of electromagnetic force heating damage spin dialysis cancer cells in blood according to claim 1, it is characterised in that：
Described filter collection organelle (2) plastics matter, tulwar sheath shape is arranged in rows on the inner surface of dialysis rotating cylinder (1) wall, is collected by filter
Organelle power line (12), electromagnetic force heating damage device (20), normal cell filter opening (21), filter collection organelle fixing bolt
(22), filter collection organelle fixed plate (23), filter Ji Xibaoqikou (24), filter collection organelle chin (25), filter collection organelle neck
(26), filter collection organelle chamber (27), filter collection organelle abdomen (28), filter collection organelle sharp (29) composition；Filter collection organelle power line
(12) it is known bifilar copper core power line, copper core is a diameter of 8-20 microns, one end is connected in parallel filter collection organelle power bus
(37), the other end is connected in parallel electromagnetic force heating damage device (20)；Normal cell filter opening (21) is divided on filter collection organelle (2) wall
The circular hole of cloth, it is a diameter of 5-8 microns；Filter collection organelle fixing bolt (22) 26S Proteasome Structure and Function is with known bolt, stainless steel；
Filter collection organelle fixed plate (23) is that filter collection organelle (2) side wall does not have the part of normal cell filter opening (21), is rotated with dialysis
Cylinder (1) wall laminating；Filter Ji Xibaoqikou (24) is the opening of filter collection organelle (2), and the direction come towards vortex is circular, diameter
For 8-15 microns；Filter collection organelle chin (25) is to filter expanding for Ji Xibaoqikou (24) rears, there is normal cell filter opening on wall
(21)；Filter collection organelle neck (26) is filter collection organelle chin (25) curved elongated passageway being upwardly formed；Filter collection organelle chamber
(27) it is to filter the inner chamber for collecting organelle (2)；Filter collection organelle abdomen (28) is that filter collection organelle (2) rear portion contains cancer cell, filtering
The part of normal plasma cell, top sets multiple electromagnetic force heating damage devices (20)；Filter collection organelle sharp (29) is filter collection cell
Device abdomen (28) rear end sharp parts, do not have normal cell filter opening (21) and electromagnetic force heating damage device (20), are cancer cell aggregation
Form a core.
3. the device of electromagnetic force heating damage spin dialysis cancer cells in blood according to claim 1, it is characterised in that：
Described vortex generator (7) be arranged on haemodialysis rotating cylinder (1) center, by spiral vortex tooth (15), motor power-supply wire (16),
Motor (17), motor power-supply wire plug (18) and spiral vortex axle (19) composition；Spiral vortex axle (19) manganese steel matter, cylinder, directly
Footpath is 1-5 centimetres, is highly 5-10 centimetres, and one end and the rotor of motor (17) are linked to be an entirety, another end dissociative, in blood
The surface of liquid dialysis rotating cylinder (1) part is provided with spiral spiral vortex tooth (15)；Spiral vortex tooth (15) manganese steel matter, is spiral
The projection of whirlpool axle (19) superficial-helical, height of projection is 1-3 centimetres, and base thickness is 0.5-0.8 centimetres, and free edge thickness is
0.1-0.2 centimetres；Motor power-supply wire (16) is known bifilar copper core power line, and copper core is a diameter of 5-10 millimeters, one end connection
Motor (17), other end connection motor power-supply wire plug (18)；Motor (17) is known motor (17).
4. the device of electromagnetic force heating damage spin dialysis cancer cells in blood according to claim 1, it is characterised in that：
Described enters a diameter of 0.5-0.8 centimetres of blood vessel (3), 0.05-1 millimeters of wall thickness, material and function blood transfusion tube, one end with known to
Syringe needle is connected with, other end connection, which is located on dialysis rotating cylinder (1) side wall, enters blood vessel head (5)；Go out blood vessel (4) a diameter of 0.5-
0.8 centimetre, 0.05-1 millimeters of wall thickness, material and function are with known blood transfusion tube, and one end connection is located at dialysis rotating cylinder (1) side wall
On bleeding tube head (6), the other end is connected with syringe needle；Control panel (8) is arranged on base with the control panel on known electrical equipment
The top of seat (36), including master switch (9), control display lamp (10) and control display board (11)；Master switch (9) is that electromagnetic force adds
Heat waste ruins the power switch of the device of spin dialysis cancer cells in blood；Display lamp (10) is controlled with known indicator lamp, with control
The chip of display board (11) processed is connected；Control display board (11) is that known LCDs and its connected chip are constituted；
General supply line plug (13) is with known three power-line plugs；General supply line (14) is known bifilar copper core power line, copper
Core diameter is 8-20 millimeters, the device of one end connection electromagnetic force heating damage spin dialysis cancer cells in blood, other end connection
General supply line plug (13).
5. the device of electromagnetic force heating damage spin dialysis cancer cells in blood according to claim 1, it is characterised in that：
Described electromagnetic force heating damage device (20) is multiple, and each electromagnetic force heating damage device (20) is by electromagnetic force heating damage needle point
(30), electromagnetic force heat production coil (31), electromagnetic force heating damage needle handle (32), electromagnetic force heating damage device pedestal (33), electromagnetism
Power heating damage device power-line plug (34) and electromagnetic force heating damage device power line (35) composition, are arranged on filter collection organelle abdomen
(28) normal cell filter opening (21) place at the top of, is miniature electromagnetic force heater, after energization, spiral electromagnetic force heat production
Coil (31) can form higher temperature, and the cancer cell that damage needle point (30) effect is in contact with it is heated by electromagnetic force, from
And scald or the boiling hot purpose ruined cancer cell, reach damage cancer cell；Electromagnetic force heating damage needle point (30) is electromagnetic force heating damage
The part that device (20) exposes to filter collection organelle chamber (27) interior direction is ruined, stainless steel is coniform, and basal diameter is 0.1-0.5
Micron, is highly 0.1-0.5 microns, and electromagnetic force heat production coil is collectively forming with the electromagnetic force heating damage needle handle (32) of its base portion
(31) axis, but do not contacted with electromagnetic force heat production coil (31), ruined so as to scald or scald cancer cell；Electromagnetic force heating damage
Needle handle (32) stainless steel, cylindric, a diameter of 0.1-0.5 microns, base portion is fixed on electromagnetic force heating damage device pedestal (33)
On；Electromagnetic force heat production coil (31) is copper, and cross section is circular, a diameter of 0.1-0.5 microns, and helical arrangement is heated in electromagnetic force
Damage outside needle handle (32), not contacted with electromagnetic force heating damage needle handle (32), heat, heating electromagnetic power are produced during for being powered
The axis that heating damage needle point (30) and electromagnetic force heating damage needle handle (32) are collectively forming；Electromagnetic force heating damage device pedestal
(33) rubber mass, cylinder is a diameter of 1-5 microns, is fixed with electromagnetic force heating damage needle handle (32) and electromagnetic force heating damage
Device power line (35), and electromagnetic force heat production coil (31) is wrapped up, it is ensured that only electromagnetic force heating damage needle point (30) is exposed to filter
Collect organelle chamber (27) interior direction；Electromagnetic force heating damage device power-line plug (34) is electromagnetic force heating damage device power line
(35) tie point being connected with filter collection organelle power line (12), ensure that the two connects together；Electromagnetic force heating damage device
Power line (35) is the wire that electric power is provided for electromagnetic force heat production coil (31), and 26S Proteasome Structure and Function is with known bifilar copper core power supply
Line, copper core cross section is circular, a diameter of 0.1-0.5 microns.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710309953.XA CN107164221B (en) | 2017-04-28 | 2017-04-28 | The device of electromagnetic force heating damage spin dialysis cancer cells in blood |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710309953.XA CN107164221B (en) | 2017-04-28 | 2017-04-28 | The device of electromagnetic force heating damage spin dialysis cancer cells in blood |
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| CN107164221A true CN107164221A (en) | 2017-09-15 |
| CN107164221B CN107164221B (en) | 2019-07-26 |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113476082A (en) * | 2021-06-15 | 2021-10-08 | 齐齐哈尔医学院 | Fat enzymolysis gravity wax-sealing type automatic collector for rabbit pancreatic cancer cells |
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| CN103781500A (en) * | 2011-06-14 | 2014-05-07 | 杭州埃夫朗生化制品有限公司 | Target-directed, magnetically enhanced system for detoxification of patients |
| CN105126239A (en) * | 2015-10-09 | 2015-12-09 | 阚士锋 | Intelligent tumor treatment device |
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|---|---|---|---|---|
| CN1748813A (en) * | 2005-09-16 | 2006-03-22 | 刘兆远 | Method and device for cocal heating of animal inner body |
| CN1986012A (en) * | 2005-12-19 | 2007-06-27 | 陈虎 | Thermostatic medical fluid heating system |
| CN103298922A (en) * | 2011-03-29 | 2013-09-11 | 南京新诺丹生物技术有限公司 | Multifunctional bioreactor system and methods for cell sorting and culturing |
| CN103781500A (en) * | 2011-06-14 | 2014-05-07 | 杭州埃夫朗生化制品有限公司 | Target-directed, magnetically enhanced system for detoxification of patients |
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| CN113476082A (en) * | 2021-06-15 | 2021-10-08 | 齐齐哈尔医学院 | Fat enzymolysis gravity wax-sealing type automatic collector for rabbit pancreatic cancer cells |
| CN113476082B (en) * | 2021-06-15 | 2022-10-21 | 齐齐哈尔医学院 | Fat enzymolysis gravity wax-sealing type automatic collector for rabbit pancreatic cancer cells |
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| Publication number | Publication date |
|---|---|
| CN107164221B (en) | 2019-07-26 |
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