CN113476082B

CN113476082B - Fat enzymolysis gravity wax-sealing type automatic collector for rabbit pancreatic cancer cells

Info

Publication number: CN113476082B
Application number: CN202110675735.4A
Authority: CN
Inventors: 郝利国; 刘丽杰; 金忠民
Original assignee: Qiqihar Medical University
Current assignee: Qiqihar Medical University
Priority date: 2021-06-15
Filing date: 2021-06-15
Publication date: 2022-10-21
Anticipated expiration: 2041-06-15
Also published as: CN113476082A

Abstract

Fat enzymolysis gravity seals wax formula rabbit pancreatic cancer cell automatic collection ware belongs to medical imaging technical field, comprises carrier ball (1), vacuole ball (2), fat stopper (3), its characterized in that: the carrier ball (1) is of a spherical saccular structure wrapping the vacuole ball (2), the vacuole ball (2) can be fixed at a specific position in the plastic sac cavity (7) after the fat plug (3) is inserted from the plug hole (8), at the moment, the connecting line between the vacuole ball (2) and the animal pole of the carrier ball (1) deviates an included angle of 10-30 degrees, the plug hole (8) is a circular truncated cone-shaped hole arranged on the animal pole of the carrier ball (1), the fat plug (3) is inserted from the plug hole (8) and is simultaneously inserted into the plug recess (11), and then the vacuole ball (2) and the carrier ball (1) are fixed together. The device has the advantages of simple manufacture, strong operability, low cost and obvious effect.

Description

Fat enzymolysis gravity wax-sealing type automatic collector for rabbit pancreatic cancer cells

Technical Field

The invention relates to a lipolysis gravity wax-sealing type automatic rabbit pancreatic cancer cell collector, belonging to the technical field of medical imaging.

Background

The tumor tunor, neoplasms, is a genetic disease, but is not inherited. It means that under the action of tumorigenic factors, the gene is changed, and the normal regulation and control of the growth of the cell are lost, so that abnormal hyperplasia is caused. Can be divided into two categories, benign and malignant tumors. The former has slow growth, clear boundary with surrounding tissues, no transfer and little harm to human health. The latter grows rapidly, can be transferred to other parts of the body, can also produce harmful substances, damage normal organ structures, cause organism dysfunction and threaten life. The tumor tissue is composed of parenchyma and stroma, and the tumor parenchyma is tumor cells, is a main component of the tumor and has tissue source specificity. It determines the biological characteristics of the tumor and the specificity of each tumor. The tissue origin of various tumors is generally identified according to the parenchymal morphology of the tumor, classification, naming and histological diagnosis of the tumor are performed, and the benign and malignant degree of the tumor and the malignant degree of the tumor are determined according to the differentiation maturity degree and the size of the heterogeneity. Tumor cells have three significant basic features: immobility, migration and loss of contact inhibition. In addition, tumor cells have many physiological, biochemical and morphological characteristics that differ from normal cells. The cancer cells are different in size and form, are generally larger than the original cells in size and have high growth speed, the nucleus-to-cytoplasm ratio is obviously higher than that of normal cells and can reach 1: 1, and the nucleus-to-cytoplasm ratio of normal differentiated cells is only 1: 4-6. The cores have different shapes and can have the phenomena of megakaryokinesis, binuclear or multinuclear. The nuclear chromosomes are aneuploidy, some chromosomes are deleted, and the number of chromosomes is increased. Abnormal changes in normal cell chromosomes initiate the apoptotic process, but in cancer cells, apoptosis-related signaling pathways become dysfunctional, i.e., cancer cells are immortal. Has migration property, cell adhesion and connection related components such as ECM and CAM are mutated or deleted, related signal pathways are blocked, and cells lose connection between cells and extracellular matrix and are easy to fall off from tumors. Many cancer cells have the ability to deform and move and produce enzymes that perforate the vascular basal lamina and connective tissue, allowing it to migrate to other tissues. Malignant epithelial cell tumors, also called cancer, are currently the most serious group of diseases that endanger human health. In the united states, mortality from malignancies is second only to cardiovascular disease. According to the 2000-year development situation statistics bulletin of the health care industry in China, the death cause of residents in urban areas is malignant tumor firstly, and cerebrovascular disease and heart disease secondly. The most common and serious tumors are lung cancer, nasopharyngeal carcinoma, esophageal cancer, gastric cancer, colorectal cancer, pancreatic cancer, liver cancer, breast cancer, cervical cancer, leukemia, lymphoma and the like. It is a common knowledge that in the precancerous stage, if a patient is examined and treated by surgery or the like, the cancer can be cured, but once cancer cells are transferred, the cancer cells are difficult to cure again, although some medicines have killing effects on the cancer cells, one thousand of killers are damaged by eight hundred, the mind and body of the patient are often greatly disabled in the retreatment process, and finally the death and fatality cannot be got rid of. The pancreas is a long narrow gland, is transversely arranged on the lumbar vertebral plane of 1-2 of the posterior abdominal wall, is soft in texture and is grayish red. The pancreas is divided into two parts of exocrine gland and endocrine gland, the exocrine gland is made up of acinus, conduit communicating with intestinal lumen, the pancreatic juice secreted contains many digestive enzymes and alkaline bicarbonate, play a role in the food digestion process "leading corner", the main function is to neutralize gastric acid, digest sugar, protein and fat, especially to the digestion of fat; the endocrine gland is composed of pancreatic islets, mainly secretes hormones such as insulin and glucagon, and has very important function on maintaining blood sugar level. Because cancer cells have immobility, mobility and loss of contact inhibition, once a small amount of cells of pancreas cancerate, the cells can enter duodenum along with pancreatic juice from a pancreatic duct in a short time, at the moment, an animal body has not too large response, and the cells are easily decomposed by the digestive juice after contacting the digestive juice, so that generally people are difficult to find pancreatic cancer in early stage, researches find that the 5-year survival rate of the pancreatic cancer in early stage is about 34%, once invading peripheral lymph nodes, the 5-year survival rate can be reduced to 12%, and if the cells are transferred remotely, the 5-year survival rate is only 3%, therefore, timely finding and early treatment are critical. Although cells enter the intestinal tract and are quickly decomposed by digestive juice, the pancreas is tightly attached to the duodenum, so that the duct of the pancreas is very short, and once the cancer cells flow out of the duct, a small part of the cancer cells are likely to remain at the opening of the duct at the large papilla of the duodenum, so that how to automatically collect a small part of the cancer cells remaining at the opening of the pancreas duct at the large papilla of the duodenum for early pathological diagnosis becomes a great problem which needs to be solved urgently.

Disclosure of Invention

The invention provides a lipolysis gravity wax-sealing type automatic rabbit pancreatic cancer cell collector, which is used for solving the problem of pathological diagnosis of early pancreatic cancer by automatically collecting a small part of residual cancer cells at the opening of a pancreatic duct at the large duodenal papilla.

The technical scheme adopted by the invention for solving the technical problem is as follows:

the invention relates to a fat enzymolysis gravity wax-sealing type automatic rabbit pancreatic cancer cell collector, which consists of a carrier ball 1, a vacuole ball 2 and a fat plug 3, and is characterized in that: the carrier ball 1 is of a spherical saccular structure wrapping the vacuole ball 2, the vacuole ball 2 can be fixed at a specific position in the plastic sac cavity 7 after the fat plug 3 is inserted from the plug hole 8, at the moment, the connecting line between the vacuole ball 2 and the animal pole of the carrier ball 1 deviates from an included angle of 10-30 degrees, the carrier ball 1 is saccular, the diameter is 1-2 mm, and the carrier ball is composed of a counterweight part 5, a plastic sac part 6, a plastic sac cavity 7 and a plug hole 8, wherein one end of the diameter of the carrier ball 1 where the counterweight part 5 is located is the plant pole of the carrier ball 1, and the other end opposite to the plant pole is provided with the plug hole 8 which is the animal pole of the carrier ball 1. The counterweight part 5 is made of stainless steel and is filled in a plastic bag cavity 7 on the inner side of the plant pole of the carrier ball 1, the upper bottom of the counterweight part 5 is circular, and the length from the center of the circle to the top point of the plant pole of the carrier ball 1 is 1/5 of the total length of the diameter of the strip. The plastic bag part 6 is the outer wall of the carrier ball 1, is made of plastic and has the thickness of 0.1-0.3 mm; the plastic bag cavity 7 is the cavity left after the plastic bag part 6 is filled with the counterweight part 5, and the plastic bag cavity 7 is internally provided with the suction ball 2. The plug hole 8 is a circular truncated cone-shaped hole arranged on the animal pole of the carrier ball 1, the diameter of the upper bottom of the circular truncated cone-shaped hole is 0.1-0.3 mm, the diameter of the lower bottom of the circular truncated cone-shaped hole is 0.08-0.24 mm, the fat plug 3 is inserted from the plug hole 8 and is simultaneously inserted into the plug concave 11, and then the vacuole ball 2 and the carrier ball 1 are fixed together.

The cell ball 2 is positioned in the plastic bag cavity 7, can move in the plastic bag cavity 7, is in a solid spherical shape, and consists of a cell ball counterweight 9, an activated carbon ball 10, a plug concave 11, an activated carbon ball fixing bag 15, a liquid paraffin brush hair area 16 and liquid paraffin brush hair 17, wherein the cell ball counterweight 9 is made of stainless steel and is filled in the activated carbon ball fixing bag 15 cavity on the inner side of a plant pole of the activated carbon ball fixing bag 15, the upper bottom of the cell ball counterweight 9 is circular, and the length from the circle center of the circle to the plant pole vertex of the cell ball 2 is 1/5 of the total length of the diameter. The activated carbon ball 10 is a round ball fixed by an activated carbon ball fixing capsule 15, is made of porous activated carbon with strong adsorbability, is exposed between a plug concave 11 and a liquid paraffin brush hair area 16, the exposed part forms one part of the surface of the activated carbon ball fixing capsule 15, the periphery of the exposed part is circular, the diameter of the circle is 0.05-0.1 mm, and pancreatic cancer cells are absorbed into the activated carbon ball 10 by the activated carbon from the position. The plug concave 11 is the part of the fat plug 3 inserted into the suction ball 2 after being inserted into the plug hole 8, is conical and is engaged with the fat plug 3, and the diameter of the conical bottom circle of the plug concave 11 is 0.08-0.24 mm. The activated carbon ball fixing bag 15 is a bag for fixing the activated carbon ball 10, the inner side of a plant pole of the activated carbon ball fixing bag is provided with a cell ball counterweight 9, the interior of the activated carbon ball 10 is provided with the activated carbon ball, the outer surface of an animal pole of the activated carbon ball fixing bag is provided with a liquid paraffin brushing area 16, a round hole is arranged on the activated carbon ball fixing bag 15 in the middle between the plug recess 11 and the liquid paraffin brushing area 16, and the activated carbon ball 10 is exposed at the round hole. The liquid paraffin brush hair area 16 is spherical and is positioned on the outer surface of the animal pole of the suction ball 2, the diameter of the circumference circle of the liquid paraffin brush hair area 16 is 0.1-0.3 mm, the liquid paraffin brush hair area 16 is provided with a plurality of liquid paraffin brush hairs 17, the liquid paraffin brush hairs 17 are plastic and are in a cilium shape, and the liquid paraffin brush hairs 17 are uniformly and densely distributed on the surface of the liquid paraffin brush hair area 16; liquid paraffin is filled between the liquid paraffin bristles 17, after the bulb sucking ball 2 is arranged in the carrier ball 1, the liquid paraffin bristles 17 in the liquid paraffin bristle field 16 and the liquid paraffin filled in the liquid paraffin bristles together form a liquid paraffin bag 4.

The fat plug 3 is fat and is integrally conical, a depression is formed in the bottom of the fat plug 3 towards the interior of the cone, the depression is a fat pit 12, and the fat pit 12 is hemispherical; the part of the periphery of the fat concave 12 positioned in the plug hole 8 is a fat plug body 13, and the thickness of the fat plug body 13 is 1/4-1/3 of the radius length of the fat concave 12; the part of the fat plug 3 inserted into the plug recess 11 is a fat plug cone 14.

The invention has the advantages that the fat enzymolysis gravity paraffin sealing type automatic rabbit pancreatic cancer cell collector firstly digests fat in food at the opening of a pancreatic duct, the pancreatic duct is very short, partial residual cancer cells are possibly in the pancreatic duct, the spherical fat enzymolysis gravity paraffin sealing type automatic rabbit pancreatic cancer cell collector is swallowed by rabbits, chyme descends to the opening of the pancreatic duct, the fat plug fixes a haustorium ball in a carrier ball at the moment, the haustorium ball has a tendency that a haustorium ball counterweight rotates towards a counterweight part, once the fat plug is digested by lipase, the tendency can drive the haustorium ball to rotate in the carrier ball, as the circular hole of the activated carbon ball fixing capsule is positioned between a plug recess and a liquid paraffin brush bristle area, the activated carbon ball is presented below the plug hole for a period of time in the rotation process of the haustorium ball, pancreatic cancer cells scattered in duodenum can enter the activated carbon ball, the activated carbon ball continues to rotate along with the haustorium ball, finally the liquid paraffin wax area is pushed below the plug hole, at the moment, the liquid paraffin wax ball in the liquid paraffin brush ball can block the gaps between the haustorium cells in the pancreatic cancer cells, and the subsequent digestive tract of the carrier. Due to the adsorption of the activated carbon, the buffer protection of the buffer solution and the closed protection of the liquid paraffin, pancreatic cancer cells are collected into the activated carbon spheres, so that the aims of automatically collecting the cancer cells, collecting the cancer cells at the later stage, culturing the cancer cells in a corresponding culture medium for pathological examination and diagnosis and further determining whether the pancreatic cancer suffers from the pancreatic cancer or not at an early stage are fulfilled. The device for the fat enzymolysis gravity wax sealing type automatic rabbit pancreatic cancer cell collector is simple to manufacture, strong in operability, low in cost and obvious in effect.

Drawings

The invention is further described below with reference to the accompanying drawings.

FIG. 1 is a schematic view of the overall structure of a lipolysis gravity wax-sealing type automatic rabbit pancreatic cancer cell collector.

FIG. 2 is a schematic diagram of a fat plug structure of the automatic collector for rabbit pancreatic cancer cells in the lipolysis gravity wax-sealing type.

FIG. 3 is a schematic diagram of a structure of a vacuole of the lipolysis gravity wax-sealing type automatic rabbit pancreatic cancer cell collector.

In the figure, 1, a carrier ball, 2, a vacuole ball, 3, a fat plug, 4, a liquid paraffin bag, 5, a weight part, 6, a plastic bag part, 7, a plastic bag cavity, 8, a plug hole, 9, a vacuole ball weight, 10, an activated carbon ball, 11, a plug concave, 12, a fat concave, 13, a fat plug body, 14, a fat plug cone, 15, an activated carbon ball fixing bag, 16, a liquid paraffin brush hair area and 17, liquid paraffin brush hair are arranged.

Detailed Description

The first embodiment is as follows:

as shown in the figure, the automatic collector for the fat enzymolysis gravity wax-sealing type rabbit pancreatic cancer cells comprises a carrier ball 1, a cyst sucking ball 2, a fat plug 3, a liquid paraffin capsule 4, a counterweight part 5, a plastic capsule part 6, a plastic capsule cavity 7, a plug hole 8, a cyst sucking ball counterweight 9, an activated carbon ball 10, a plug recess 11, a fat recess 12, a fat plug body 13, a fat plug cone 14, an activated carbon ball fixing capsule 15, a liquid paraffin brush hair area 16 and liquid paraffin brush hair 17. The carrier ball 1 is a spherical bag-shaped structure wrapping the vacuole ball 2, after the fat plug 3 is inserted from the plug hole 8, the vacuole ball 2 can be fixed at a specific position in the plastic bag cavity 7, at the moment, the connecting line between the vacuole ball 2 and the animal pole of the carrier ball 1 deviates from an included angle of 10-30 degrees, when the fat plug 3 is degraded by pancreatic lipase, the animal pole of the vacuole ball 2 reaches the position of the plug hole 8 under the action of the vacuole ball counterweight 9, and simultaneously, the liquid paraffin at the liquid paraffin brush area 16 of the animal pole of the vacuole ball 2 can block the plug hole 8 to prevent enzymes in intestinal tracts from entering the vacuole ball 2, so that a small part of pancreatic cancer cells remained at the opening of the pancreatic duct overflowing to the duodenum large nipple are automatically collected by the activated carbon ball 10, the carrier ball 1 is in a bag shape, the diameter is 1-2 mm, and consists of a counterweight part 5, a plastic bag part 6, a plastic bag cavity 7 and the plug hole 8, wherein one end of the diameter of the carrier ball 1 is the plant pole of the carrier ball 1, and the plant pole is opposite to the plant ball 8. The counterweight part 5 is made of stainless steel and is filled in a plastic bag cavity 7 on the inner side of a plant pole of the carrier ball 1, the upper bottom of the counterweight part 5 is circular, the length from the center of the circle to the plant pole top point of the carrier ball 1 is 1/5 of the total diameter of the carrier ball, the counterweight part 5 is made of stainless steel and has density higher than that of plastic, so that the counterweight part acts like a tumbler under the action of gravity, when the carrier ball 1 is swallowed to the opening of a pancreatic duct at the U-shaped bent bottom of a duodenum through a mouth, the plant pole of the carrier ball 1 faces downwards, the animal pole faces upwards, once the fat plug 3 is hydrolyzed by lipase, the plane of the upper bottom circle of the suction ball counterweight 9 of the suction ball 2 is parallel to the plane of the upper bottom circle of the counterweight part 5, so that the liquid paraffin brush area 16 is positioned at the plug hole 8, and the plug hole 8 is sealed by liquid paraffin, and pancreatic cancer cells entering the activated carbon ball 10 are prevented from being digested by enzyme in an intestinal tract. The plastic bag part 6 is the outer wall of the carrier ball 1, is made of plastic and has the thickness of 0.1-0.3 mm; the plastic bag cavity 7 is a cavity left after the plastic bag part 6 is filled with the counterweight part 5, and the plastic bag cavity 7 is internally provided with the suction ball 2. The plug hole 8 is a circular truncated cone-shaped hole arranged on the animal pole of the carrier ball 1, the diameter of the upper bottom of the circular truncated cone-shaped hole is 0.1-0.3 mm, the diameter of the lower bottom of the circular truncated cone-shaped hole is 0.08-0.24 mm, the fat plug 3 can be inserted from the plug hole 8 and simultaneously inserted into the plug recess 11, and then the vacuole ball 2 and the carrier ball 1 are fixed together. The suction cell ball 2 is of a ball structure for adsorbing pancreatic cancer cells, is positioned in the plastic bag cavity 7, can move in the plastic bag cavity 7, is in a solid spherical shape, and consists of a suction cell ball counterweight 9, an activated carbon ball 10, a plugging concave 11, an activated carbon ball fixing bag 15, a liquid paraffin brush hair area 16 and liquid paraffin brush hair 17, wherein the suction cell ball counterweight 9 is made of stainless steel and is filled in the activated carbon ball fixing bag 15 cavity on the inner side of a plant pole of the activated carbon ball fixing bag 15, the upper bottom of the suction cell ball counterweight 9 is in a circular shape, the length from the circle center of the circle to the plant pole vertex of the suction cell ball 2 is 1/5 of the total diameter of the suction cell ball, as the suction cell ball counterweight 9 is made of stainless steel and has higher density than plastic, under the action of gravity, like a tumbler, when the carrier ball 1 swallows to a pancreatic duct opening at the U-shaped bent bottom of a duodenum through the mouth, the plant pole of the suction cell ball 2 can be ensured to face downwards, the animal pole faces upwards, once the fat plug 3 is hydrolyzed by lipase, the suction cell ball 2 can be in the liquid paraffin brush hair area 8, and the liquid paraffin plug area can be blocked by the liquid paraffin wax area 8. The activated carbon sphere 10 is a sphere fixed by an activated carbon sphere fixing capsule 15 and is made of porous activated carbon with strong adsorbability and buffer solution for ensuring the activity of sucked pancreatic cancer cells, the buffer solution is made of tissue fluid in pancreas, the amount of the buffer solution is kept to be half of the total volume of a space formed by pores in the activated carbon sphere 10, the activated carbon sphere 10 is exposed between a plug recess 11 and a liquid paraffin brush bristle area 16, the exposed part forms one part of the surface of the activated carbon sphere fixing capsule 15, the periphery of the part is circular, the diameter of the circle is 0.05-0.1 mm, and the pancreatic cancer cells are sucked into the activated carbon sphere 10 by the activated carbon from the part. The plug concave 11 is the part of the fat plug 3 inserted into the plug hole 8 and then inserted into the suction ball 2, is conical and is engaged with the fat plug 3, and the diameter of the bottom circle of the cone is 0.08-0.24 mm. The activated carbon ball fixing capsule 15 is a capsule for fixing the activated carbon ball 10, a cell sucking ball counterweight 9 is arranged on the inner side of a plant pole, the activated carbon ball 10 is arranged in the activated carbon ball fixing capsule, a liquid paraffin brushing area 16 is arranged on the outer surface of an animal pole, a round hole is arranged on the activated carbon ball fixing capsule 15 in the middle between the plug concave 11 and the liquid paraffin brushing area 16, and the activated carbon ball 10 is exposed at the round hole. The liquid paraffin brush hair area 16 is spherical and is positioned on the outer surface of the animal polar of the suction ball 2, the diameter of the periphery circle of the liquid paraffin brush hair area 16 is 0.1-0.3 mm, the liquid paraffin brush hair area 16 is provided with a plurality of liquid paraffin brush hair 17, the liquid paraffin brush hair 17 is made of plastic and is in a cilium shape and is uniformly and densely distributed on the surface of the liquid paraffin brush hair area 16; liquid paraffin is filled between the liquid paraffin brush hairs 17, after the suction ball 2 is arranged in the carrier ball 1, the liquid paraffin brush hairs 17 of the liquid paraffin brush hair area 16 and the liquid paraffin filled in the liquid paraffin brush hairs together form a liquid paraffin bag 4. When the fat plug 3 fixes the haustorium ball 2 in the carrier ball 1, the haustorium ball 2 has a tendency that the haustorium ball counterweight 9 rotates towards the counterweight part 5, once the fat plug 3 is digested by lipase, the haustorium ball 2 can be driven to rotate in the carrier ball 1 by the tendency, and as the round hole of the activated carbon ball fixing bag 15 is positioned between the plug recess 11 and the liquid paraffin brush bristle area 16, the activated carbon ball 10 is presented below the plug hole 8 for a period of time in the rotation process of the haustorium ball 2, pancreatic cancer cells escaped from duodenum can enter the activated carbon ball 10 at the stage, and can be separated and cultured in the subsequent pathological examination, so that the examiner can be diagnosed to have pancreatic cancer; as the haustorium ball 2 continues to rotate, finally the liquid paraffin brush hair area 16 is pushed to the position below the plug hole 8, and at the moment, the liquid paraffin of the liquid paraffin capsule 4 can seal the gap between the haustorium ball 2 and the carrier ball 1 below the plug hole 8 so as to prevent digestive enzyme in subsequent intestinal tracts from damaging pancreatic cancer cells in the activated carbon ball 10. The fat plug 3 is a structure for fixing the vacuole ball 2 in the carrier ball 1, is fat and is integrally conical, and the fat plug 3 is just engaged with a conical recess formed by the plug hole 8 and the plug recess 11. The fat plug 3 is provided with a depression in the bottom of the cone towards the interior of the cone, the depression is a fat pit 12, and the fat pit 12 is hemispherical and is arranged for reducing the amount of the fat plug 3 so that lipase can more quickly decompose the fat plug 3; the part of the periphery of the fat pit 12, which is positioned in the plug hole 8, is a fat plug body 13, and the thickness of the fat plug body 13 is 1/4-1/3 of the radius length of the fat pit 12; the part of the fat plug 3 inserted into the plug recess 11 is a fat plug cone 14, and the fat plug body 13 and the fat plug cone 14 form the entity of the fat plug 3.

The foregoing shows and describes the general principles and broad features of the present invention and advantages thereof. It will be understood by those skilled in the art that the present invention is not limited to the embodiments described above, which are merely illustrative of the principles of the invention, but that various changes and modifications may be made without departing from the spirit and scope of the invention, which is defined by the appended claims and their equivalents.

Claims

1. Fat enzymolysis gravity seals wax formula rabbit pancreatic cancer cell automatic collection ware comprises carrier ball (1), vacuole ball (2), fat stopper (3), its characterized in that: the carrier ball (1) is of a spherical sac-shaped structure wrapping the vacuole ball (2), the vacuole ball (2) can be fixed at a specific position in the plastic sac cavity (7) after the fat plug (3) is inserted from the plug hole (8), at the moment, the connecting line between the vacuole ball (2) and the animal pole of the carrier ball (1) deviates an included angle of 10-30 degrees, the carrier ball (1) is of a saccule shape, the diameter of the carrier ball is 1-2 mm, and the carrier ball consists of a counterweight part (5), a plastic sac part (6), the plastic sac cavity (7) and the plug hole (8), wherein one end of the diameter of the carrier ball (1) where the counterweight part (5) is located is the plant pole of the carrier ball (1), and the other end opposite to the plant pole is provided with the plug hole (8) which is the animal pole of the carrier ball (1); the counterweight part (5) is made of stainless steel and is filled in a plastic bag cavity (7) on the inner side of the plant pole of the carrier ball (1), the upper bottom of the counterweight part (5) is circular, and the length from the center of the circle to the plant pole vertex of the carrier ball (1) is 1/5 of the total length of the diameter of the carrier ball (1) where the center of the circle of the upper bottom circle of the counterweight part (5) is located; the plastic bag part (6) is the outer wall of the carrier ball (1), is made of plastic and has the thickness of 0.1-0.3 mm; the plastic bag cavity (7) is a cavity left after the plastic bag part (6) is filled with the counterweight part (5), and a suction ball (2) is arranged in the plastic bag cavity (7); the plug hole (8) is a circular truncated cone-shaped hole arranged on the animal pole of the carrier ball (1), the diameter of the upper bottom of the circular truncated cone-shaped hole is 0.1-0.3 mm, the diameter of the lower bottom of the circular truncated cone-shaped hole is 0.08-0.24 mm, the fat plug (3) is inserted from the plug hole (8) and simultaneously inserted into the plug recess (11), and then the vacuole ball (2) and the carrier ball (1) are fixed together; the cell ball (2) is positioned in the plastic bag cavity (7), can move in the plastic bag cavity (7), is in a solid spherical shape, and consists of a cell ball counterweight (9), an activated carbon ball (10), a plug concave (11), an activated carbon ball fixing bag (15), a liquid paraffin brush hair area (16) and liquid paraffin brush hair (17), wherein the cell ball counterweight (9) is made of stainless steel and is filled in the activated carbon ball fixing bag (15) cavity on the inner side of a plant pole of the activated carbon ball fixing bag (15), the upper bottom of the cell ball counterweight (9) is circular, and the length from the center of the circle to the top point of the plant pole of the cell ball (2) is 1/5 of the total length of the diameter of the cell ball (2) where the center of the circle of the upper bottom circle of the cell ball counterweight (9) is located; the activated carbon ball (10) is a round ball fixed by an activated carbon ball fixing capsule (15), is made of porous activated carbon with strong adsorbability, is exposed between a plug concave (11) and a liquid paraffin brush hair area (16), the exposed part forms one part of the surface of the activated carbon ball fixing capsule (15), the periphery of the exposed part is circular, the diameter of the circle is 0.05-0.1 mm, and pancreatic cancer cells are absorbed into the activated carbon ball (10) by the activated carbon from a round hole of the activated carbon ball fixing capsule; the plug concave (11) is a conical part which is inserted into the suction ball (2) after the fat plug (3) is inserted into the plug hole (8) and is engaged with the fat plug (3), and the diameter of the conical bottom circle of the plug concave (11) is 0.08-0.24 mm; the activated carbon ball fixing bag (15) is a bag for fixing the activated carbon ball (10), the inner side of a plant pole of the activated carbon ball fixing bag is provided with a cell ball counterweight (9), the activated carbon ball (10) is arranged in the activated carbon ball fixing bag, the outer surface of an animal pole of the activated carbon ball fixing bag is provided with a liquid paraffin brushing area (16), a round hole is formed in the activated carbon ball fixing bag (15) in the middle between the plug recess (11) and the liquid paraffin brushing area (16), and the activated carbon ball (10) is exposed at the round hole; the liquid paraffin brush hair area (16) is spherical and is positioned on the outer surface of the animal pole of the cyst ball (2), the diameter of the periphery circle of the liquid paraffin brush hair area (16) is 0.1-0.3 mm, the liquid paraffin brush hair area (16) is provided with a plurality of liquid paraffin brush hairs (17), the liquid paraffin brush hairs (17) are plastic and are ciliated and are uniformly and densely distributed on the surface of the liquid paraffin brush hair area (16); liquid paraffin is filled between the liquid paraffin brush hairs (17), after the cell sucking ball (2) is arranged in the carrier ball (1), the liquid paraffin brush hairs (17) of the liquid paraffin brush hair area (16) and the liquid paraffin filled in the liquid paraffin brush hairs form a liquid paraffin bag (4) together; the fat plug (3) is fat and is integrally conical, a depression is formed in the bottom of the fat plug (3) towards the interior of the cone, the depression is a fat pit (12), and the fat pit (12) is hemispherical; the part of the periphery of the fat recess (12) positioned in the plug hole (8) is a fat plug body (13), and the thickness of the fat plug body (13) is 1/4-1/3 of the radius length of the fat recess (12); the part of the fat plug (3) inserted into the plug recess (11) is a fat plug cone (14).