CN107158214A - A kind of antibacterial cold dispelling rhinitis ointment and preparation method thereof - Google Patents

A kind of antibacterial cold dispelling rhinitis ointment and preparation method thereof Download PDF

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Publication number
CN107158214A
CN107158214A CN201710413103.4A CN201710413103A CN107158214A CN 107158214 A CN107158214 A CN 107158214A CN 201710413103 A CN201710413103 A CN 201710413103A CN 107158214 A CN107158214 A CN 107158214A
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root
cold dispelling
rhinitis
adjuvant
achene
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李中国
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Chongqing Grass Biotechnology Co Ltd
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Chongqing Grass Biotechnology Co Ltd
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    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
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Abstract

The invention discloses a kind of antibacterial cold dispelling rhinitis ointment, including main ingredient and adjuvant, wherein main ingredient is made up of the bulk drug of following parts by weight:Centipeda minima;The achene of Siberian cocklebur;The flower bud of lily magnolia;The root of Dahurain angelica;Medicine xiaolingxian;Paper mulberry Fruit;Cottonrose hibiscus leaf;Cordate houttuynia and first pearl;Adjuvant is made up of the bulk drug of following parts by weight:Chrysanthemum, luffa, the root bark of white mulberry, asarum, peppermint, flat shellfish, day fourth, schizonepeta, the Radix Astragali, radix glycyrrhizae;The present invention is by using Centipeda minima, the achene of Siberian cocklebur, the flower bud of lily magnolia, the root of Dahurain angelica, medicine xiaolingxian, Paper mulberry Fruit, cottonrose hibiscus leaf, cordate houttuynia and first pearl as main ingredient, for curing mainly anti-inflammatory, antibacterial, cold dispelling, it is equipped with luffa, the root bark of white mulberry, asarum, flat shellfish, day fourth, schizonepeta, the Radix Astragali, radix glycyrrhizae etc. are adjuvant, clearing heat for detumescence, removing toxic substances cold dispelling, anti-inflammation, the purpose of sensible desensitization are reached, it is low for treating rhinitis, nasosinusitis, fast rhinoedema and allergic rhinitis curative effect, good effect, recurrence rate.

Description

A kind of antibacterial cold dispelling rhinitis ointment and preparation method thereof
Technical field
The invention belongs to the technical field containing antigen or the pharmaceutical product of antibody, a kind of antibacterial cold dispelling is specifically related to With rhinitis ointment and preparation method thereof.
Background technology
Rhinitis is nasal cavity inflammatory disease, is virus, bacterium, allergen, various physical and chemical factors and some systemic diseases The inflammation of caused bronchia mucosal.The main pathological change of rhinitis is bronchia mucosal hyperemia, swelling, ooze out, hyperplasia, atrophy or bad Wait indefinitely.
Mainly there is following several method in the treatment of current rhinitis:
1st, oral drugs:Primarily directed to rhinitis protopathy because being treated, according to different rhinitis medications area Not, anaphylaxis rhinitis needs antianaphylactic treatment, and general rhinitis can take HUODAN WAN, a variety of rhinitis tablets etc..Atrophic nose It is scorching then need to take vitamin medicaments.
2nd, local Collunarium medicine:Collunarium medicine is typically mainly used to alleviate the symptom of rhinitis, and nose oil can alleviate drying property The drying of rhinitis, FUMA HEJI can then alleviate congestion, and steroids nasal drops then contributes to mitigate beating for allergic rhinitis The symptoms such as sneeze stream clear water nasal mucus;
3rd, operative treatment:Operation be mainly used in medicine can not treat or DeGrain rhinitis, can solve nasal obstruction.It is suitable For the loose caused congestion of concha, or nasal cavity extremely atrophic rhinitis of drying etc.;
4th, laser or micro-wave therapeutic:Suitable for congestion, and there is certain benefit to sneezing, do not solve typically to have a running nose The problem of.
The content of the invention
In view of this, it is an object of the invention to provide a kind of antibacterial cold dispelling rhinitis ointment and preparation method thereof, the one kind Antibacterial cold dispelling rhinitis ointment passes through with Centipeda minima, the achene of Siberian cocklebur, the flower bud of lily magnolia, the root of Dahurain angelica, medicine xiaolingxian, Paper mulberry Fruit, cottonrose hibiscus leaf, cordate houttuynia and first Pearl is main ingredient, for curing mainly anti-inflammatory, antibacterial, cold dispelling, is equipped with luffa, the root bark of white mulberry, asarum, flat shellfish, day fourth, schizonepeta, the Radix Astragali, sweet Grass wait be adjuvant, reach clearing heat for detumescence, removing toxic substances cold dispelling, anti-inflammation, the purpose of sensible desensitization, for treat rhinitis, nasosinusitis, Rhinoedema and allergic rhinitis curative effect are fast, good effect, recurrence rate are low.
In order to achieve the above object, a kind of antibacterial cold dispelling rhinitis ointment of the present invention, including main ingredient and adjuvant, wherein main ingredient by The bulk drug of following parts by weight is made:10~25g of Centipeda minima;20~40g of the achene of Siberian cocklebur;20~40g of the flower bud of lily magnolia;20~40g of the root of Dahurain angelica; 10~25g of medicine xiaolingxian;20~40g of Paper mulberry Fruit;20~40g of cottonrose hibiscus leaf;10~25g of cordate houttuynia;10~25g of first pearl;
Adjuvant is made up of the bulk drug of following parts by weight:0~25g of chrysanthemum, 0~25g of luffa, 10~25g of the root bark of white mulberry, carefully Pungent 5~15g, 0~25g of peppermint, flat 10~25g of shellfish, day 10~25g of fourth, 10~25g of schizonepeta, 10~25g of the Radix Astragali, radix glycyrrhizae 0~ 15g。
Further, the parts by weight of each bulk drug are respectively:Centipeda minima 20g;Achene of Siberian cocklebur 30g;Flower bud of lily magnolia 30g;Root of Dahurain angelica 30g; Medicine xiaolingxian 20g;Paper mulberry Fruit 30g;Cottonrose hibiscus leaf 30g;Cordate houttuynia 20g;First pearl 15g;Chrysanthemum 15g, luffa 15g, root bark of white mulberry 15g, carefully Pungent 10g, peppermint 15g, flat shellfish 15g, day fourth 15g, schizonepeta 15g, Radix Astragali 15g, radix glycyrrhizae 10g.
The invention also discloses a kind of preparation method of antibacterial cold dispelling rhinitis ointment, its step is:
1) main ingredient composition Centipeda minima is proportionally taken;The achene of Siberian cocklebur;The flower bud of lily magnolia;The root of Dahurain angelica;Medicine xiaolingxian;Paper mulberry Fruit;Cottonrose hibiscus leaf;Fish raw meat Grass and first pearl, adjuvant luffa, the root bark of white mulberry, day fourth and schizonepeta;Solarization roasting, which smashes to clay into power, to be mixed;
2) proportionally take chrysanthemum, asarum, peppermint, flat shellfish, the Radix Astragali, radix glycyrrhizae to mix and high temperature infusion is carried out after water, divide after mixing Decocted into more than secondary, through filter and remove residue, then obtain decoction by each time and be mixed at one, slow fire is tempered, and endures sticky to liquor strength;
3) mixed-powder is fallen into the liquid to be stirred mixing.
Further, in step 3) in, 15%~20% vaseline of addition is mixed.
The property of medicine of Main Ingredients and Appearance is as follows in the present invention:
First pearl:Blood circulation promoting and dispersing pathogen accumulation, detumescence and apocenosis, anti-inflammatory;
Centipeda minima:Cold dispelling is antibacterial, resolving sputum, expelling wind and promoting the restoration of consciousness;
The achene of Siberian cocklebur:Cold dispelling is sensible, inhibiting bacteria and diminishing inflammation;
The flower bud of lily magnolia:Cold dispelling profit key, temperature are promoted blood circulation network;
The root of Dahurain angelica:Repellent antipruritic, apocenosis of invigorating blood circulation, cold dispelling are sensible;
Medicine xiaolingxian:Dispelling wind and eliminating dampness, remove obstruction in channels to relieve pain;
Paper mulberry Fruit:Oedema turgor, anti-inflammatory;
Cottonrose hibiscus leaf:Lung-heat clearing and detoxification, detumescence;
Cordate houttuynia:Clearing heat and detoxicating, anti-inflammatory is antibacterial, the pain that disappears apocenosis.
The beneficial effects of the present invention are:
A kind of antibacterial cold dispelling rhinitis ointment of the present invention passes through with Centipeda minima, the achene of Siberian cocklebur, the flower bud of lily magnolia, the root of Dahurain angelica, medicine xiaolingxian, paper mulberry fruit Son, cottonrose hibiscus leaf, cordate houttuynia and first pearl are main ingredient, for curing mainly anti-inflammatory, antibacterial, cold dispelling, are equipped with luffa, the root bark of white mulberry, asarum, flat Shellfish, day fourth, schizonepeta, the Radix Astragali, radix glycyrrhizae etc. are adjuvant, reach clearing heat for detumescence, removing toxic substances cold dispelling, anti-inflammation, the purpose of sensible desensitization, It is low for treating rhinitis, nasosinusitis, fast rhinoedema and allergic rhinitis curative effect, good effect, recurrence rate.
Embodiment
Embodiment 1:
Weigh Centipeda minima 20g;Achene of Siberian cocklebur 30g;Flower bud of lily magnolia 30g;Root of Dahurain angelica 30g;Medicine xiaolingxian 20g;Paper mulberry Fruit 30g;Cottonrose hibiscus leaf 30g;Cordate houttuynia 20g, first pearl 15g, luffa 15g, root bark of white mulberry 15g, day fourth 15g, schizonepeta 15g;Shine roasting smash clay into power into Row mixing;Weigh chrysanthemum 15g, asarum 10g, peppermint 15g, flat shellfish 15g, Radix Astragali 15g, radix glycyrrhizae 10g and mix progress high temperature infusion after water, After mixing in two times more than decoct into, through filter and remove residue, then obtain decoction by each time and be mixed at one, slow fire is tempered, and is endured to decoction Concentration is sticky;Mixed-powder is fallen and into the liquid is stirred mixing.
Consumption usage:Clean after nasal cavity, get it filled cream 0.5ml (children take the circumstances into consideration decrement), feeding nasal cavity 0.5-2cm is deep, with suitable When the cotton balls of size clogs nostril, flowed out to prevent medicine;Same method carries out another nostril;Adult's reservation more than 1 hour, often It is once used in conjunction 7 days, shares 7 times, is a course for the treatment of.
Embodiment 2:
Weigh Centipeda minima 10g;Achene of Siberian cocklebur 20g;Flower bud of lily magnolia 20g;Root of Dahurain angelica 20g;Medicine xiaolingxian 10g;Paper mulberry Fruit 20g;Cottonrose hibiscus leaf 20g;Cordate houttuynia 20g, first pearl 10g, luffa 20g, root bark of white mulberry 20g, day fourth 20g, schizonepeta 20g;Shine roasting smash clay into power into Row mixing;Weigh chrysanthemum 20g, asarum 15g, peppermint 20g, flat shellfish 20g, Radix Astragali 20g, radix glycyrrhizae 15g and mix progress high temperature infusion after water, After mixing in two times more than decoct into, through filter and remove residue, then obtain decoction by each time and be mixed at one, slow fire is tempered, and is endured to decoction Concentration is sticky;Mixed-powder is fallen and into the liquid is stirred mixing.
Consumption usage:Described in be the same as Example 1.
Embodiment 3:
Weigh Centipeda minima 25g;Achene of Siberian cocklebur 40g;Flower bud of lily magnolia 40g;Root of Dahurain angelica 40g;Medicine xiaolingxian 25g;Paper mulberry Fruit 40g;Cottonrose hibiscus leaf 40g;Cordate houttuynia 40g, first pearl 25g, luffa 0g, root bark of white mulberry 10g, day fourth 10g, schizonepeta 10g;Shine roasting and smash progress of claying into power Mixing;Weigh chrysanthemum 0g, asarum 5g, peppermint 0g, flat shellfish 10g, Radix Astragali 10g, radix glycyrrhizae 0g and mix progress high temperature infusion after water, after mixing Decocted into more than in two times, through filter and remove residue, then obtain decoction by each time and be mixed at one, slow fire is tempered, endured to liquor strength and stick It is thick;Mixed-powder is into the liquid, it is stirred mixing adding 20% vaseline.
Consumption usage:Described in be the same as Example 1.
To prove that the present invention has good curative effect, model case is enumerated as follows:
Case one:
Poplar, female, 33 years old now, Jiulongpo District Yang Jiaping people, with rhinitis 6 years, continuation was had a running nose, nasal obstruction;Use One course for the treatment of of ointment that embodiment two is configured, symptom disappears, and ventilates, no nasal mucus, and continuous observation 2 years is without recurrence.
Case two:
Wu, man, 35 years old now, people from village of Dadukou District great Yan 3, with chronic nasosinusitis 12 years, nasal obstruction and nasal mucus is purulence Tears, obstinate.Two courses for the treatment of of ointment configured using embodiment two, nasal obstruction, headache syndromes are disappeared, and bronchia mucosal is repaired, Continuous observation 3 years is without recurrence.
Case three:
Liu, female, 46 years old now, Jiulongpo District Ba Guo people from cities, with allergic rhinitis 2 years, early morning, which got up, to sneeze, Permanent current clear water sample nasal mucus, with nasal obstruction and rhiocnesmus symptom.One course for the treatment of of ointment configured using embodiment three, symptom is disappeared, and is led to Gas is good, and continuous observation does not recur for 2 years.
Case four:
Dong, female, 37 years old now, Jiulongpo District Ba Guo people from cities suffered from rhinitis chronic 2 years, nasal obstruction, occasionally has headache, there is forehead Intermittent distending pain, concha enlargement;One course for the treatment of of ointment configured using embodiment one, nasal airflow is good, and headache disappears, lasting to see Examine 2 years and do not recur.
Case five:
Zhu, man, 48 years old now, big people from level ground in Yu Zhong district, with chronic nasosinusitis 25 years, headache, nasal obstruction is serious, and stream has purulence Tears, bronchia mucosal has rotten to the corn phenomenon, after one course for the treatment of of ointment configured using embodiment one, headache, and nasal obstruction symptom disappears, nasal cavity Mucosal erosion mitigates, and reuses a course for the treatment of, and symptom disappears, and bronchia mucosal is repaired good;Continuous observation does not recur for 3 years.
Finally illustrate, preferred embodiment above is merely illustrative of the technical solution of the present invention and unrestricted, although logical Cross above preferred embodiment the present invention is described in detail, it is to be understood by those skilled in the art that can be Various changes are made to it in form and in details, without departing from claims of the present invention limited range.

Claims (4)

1. a kind of antibacterial cold dispelling rhinitis ointment, it is characterised in that:Including main ingredient and adjuvant, wherein main ingredient by following parts by weight original Material medicine is made:10~25g of Centipeda minima;20~40g of the achene of Siberian cocklebur;20~40g of the flower bud of lily magnolia;20~40g of the root of Dahurain angelica;10~25g of medicine xiaolingxian;Paper mulberry 20~40g of real son;20~40g of cottonrose hibiscus leaf;10~25g of cordate houttuynia;10~25g of first pearl;
Adjuvant is made up of the bulk drug of following parts by weight:0~25g of chrysanthemum, 0~25g of luffa, 10~25g of the root bark of white mulberry, asarum 5 ~15g, 0~25g of peppermint, flat 10~25g of shellfish, day 10~25g of fourth, 10~25g of schizonepeta, 10~25g of the Radix Astragali, 0~15g of radix glycyrrhizae.
2. a kind of antibacterial cold dispelling rhinitis ointment according to claim 1, it is characterised in that:The parts by weight difference of each bulk drug It is:Centipeda minima 20g;Achene of Siberian cocklebur 30g;Flower bud of lily magnolia 30g;Root of Dahurain angelica 30g;Medicine xiaolingxian 20g;Paper mulberry Fruit 30g;Cottonrose hibiscus leaf 30g;Cordate houttuynia 20g;First pearl 15g;Chrysanthemum 15g, luffa 15g, root bark of white mulberry 15g, asarum 10g, peppermint 15g, flat shellfish 15g, day fourth 15g, schizonepeta 15g, Radix Astragali 15g, radix glycyrrhizae 10g.
3. a kind of a kind of method of the antibacterial cold dispelling rhinitis ointment prepared described in claim 1 or 2, it is characterised in that its step It is as follows:
1) main ingredient composition Centipeda minima is proportionally taken;The achene of Siberian cocklebur;The flower bud of lily magnolia;The root of Dahurain angelica;Medicine xiaolingxian;Paper mulberry Fruit;Cottonrose hibiscus leaf;Cordate houttuynia and First pearl, adjuvant luffa, the root bark of white mulberry, day fourth and schizonepeta;Solarization roasting, which smashes to clay into power, to be mixed;
2) proportionally take chrysanthemum, asarum, peppermint, flat shellfish, the Radix Astragali, radix glycyrrhizae to mix and high temperature infusion is carried out after water, after mixing in two times Decoct into above, through filter and remove residue, then obtain decoction by each time and be mixed at one, slow fire is tempered, and endures sticky to liquor strength;
3) mixed-powder is fallen into the liquid to be stirred mixing.
4. a kind of preparation method of antibacterial cold dispelling rhinitis ointment according to claim 3, it is characterised in that:In step 3) In, 15%~20% vaseline of addition is mixed.
CN201710413103.4A 2017-06-05 2017-06-05 A kind of antibacterial cold dispelling rhinitis ointment and preparation method thereof Pending CN107158214A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106085691A (en) * 2016-06-07 2016-11-09 湖北爽露爽食品股份有限公司 A kind of plant source rice wine koji composes fragrant antibacterial and its preparation method and application
CN107875228A (en) * 2017-11-30 2018-04-06 云南露源野生真菌研究所(有限合伙) A kind of Chinese medicine for treating rhinitis preparation and preparation method thereof

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106085691A (en) * 2016-06-07 2016-11-09 湖北爽露爽食品股份有限公司 A kind of plant source rice wine koji composes fragrant antibacterial and its preparation method and application
CN107875228A (en) * 2017-11-30 2018-04-06 云南露源野生真菌研究所(有限合伙) A kind of Chinese medicine for treating rhinitis preparation and preparation method thereof

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Application publication date: 20170915