CN107137476A - A kind of Chinese herbal feed additive for improving porkling resistance against diseases and preparation method thereof - Google Patents

A kind of Chinese herbal feed additive for improving porkling resistance against diseases and preparation method thereof Download PDF

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Publication number
CN107137476A
CN107137476A CN201710239307.0A CN201710239307A CN107137476A CN 107137476 A CN107137476 A CN 107137476A CN 201710239307 A CN201710239307 A CN 201710239307A CN 107137476 A CN107137476 A CN 107137476A
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parts
chinese herbal
feed additive
resistance against
against diseases
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莫模双
熊文婕
严小东
曹国敏
覃海
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Fangchenggang City Animal Epidemic Prevention And Control Center
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Fangchenggang City Animal Epidemic Prevention And Control Center
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/13—Coniferophyta (gymnosperms)
    • A61K36/14—Cupressaceae (Cypress family), e.g. juniper or cypress
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
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    • A23K10/00—Animal feeding-stuffs
    • A23K10/30—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/30—Feeding-stuffs specially adapted for particular animals for swines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/07—Basidiomycota, e.g. Cryptococcus
    • A61K36/076—Poria
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/486—Millettia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/489—Sophora, e.g. necklacepod or mamani
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/61—Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/68—Plantaginaceae (Plantain Family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/738—Rosa (rose)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50—Methods involving additional extraction steps
    • A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50—Methods involving additional extraction steps
    • A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

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Abstract

The invention belongs to feed addictive research and development technology field, more particularly to a kind of Chinese herbal feed additive for improving porkling resistance against diseases and preparation method thereof.A kind of Chinese herbal feed additive for improving porkling resistance against diseases, is made up of following raw material by weight：6 18 parts of 10 25 parts of cacumen biotae, 10 35 parts of Asiatic plantain, 10 30 parts of reticulate millettia, 15 35 parts of the fruit of Cherokee rose, 3 10 parts of cloves, 20 40 parts of the bark of eucommia, 15 35 parts of kuh-seng, 6 12 parts of Poria cocos and teasel root.The Chinese herbal feed additive of the raising porkling resistance against diseases of the present invention carries out compounding by plurality of Chinese component and formed, and using pure Chinese medicine composition, has no toxic side effect；For pig bacterial disease, especially there is good prevention and treatment effect to bacteriosises such as brickpox, swine plague, swine escherichia coli, the red dysentery of pig；Its raw material is easy to get, and medicine source is wide, and convenient material drawing can be promoted the use of.

Description

A kind of Chinese herbal feed additive for improving porkling resistance against diseases and preparation method thereof
Technical field
The invention belongs to feed addictive research and development technology field, more particularly to a kind of Chinese medicine for improving porkling resistance against diseases is raised Feed additives and preparation method thereof.
Background technology
With the economic raising developed rapidly with living standards of the people, on people are continuous to the demands of consumption of meat product Liter, wherein pork are in whole consumption of meat more than 60%.But, the resistance against diseases of market pig is worse and worse, it is easy to by The infringement of various disease, exerts a certain influence to the normal growth and breeding of pig, and particularly some bacteriosises can be tight The development of pig industry is impacted again.Accordingly, it would be desirable to pay attention to the preventing and treating to pig bacterial disease.
Correlation study research finds that the bacteriosis of pig occurs mainly in respiratory system and gi system, wherein, It is relatively common for brickpox, piglet yellow scour, paratyphoid, the white scour of piglet and oedema etc..Common bacterial respiratory tract disease Including swine paratyphoid, Streptococcus suis, the bloodthirsty bar germ of secondary pig, porcine contagious pleuropneumonia and infectiousness atrophic rhinitis etc.. Different bacteriosis, it is easy to reduce the production capacity of pig or cause the death of pig, heavy damage and have impact on pig industry Development.Related practical studies show, give mammal herbal control, with strengthen its resistance, antibacterial, regulation body The effect such as immune, anti-inflammatory and inducement interferon, particularly has good preventive and therapeutic action to bacteriosis.
The information for being disclosed in the background section is merely intended to understanding of the increase to the general background of the present invention, without answering When the prior art for being considered as recognizing or implying the information structure in any form well known to persons skilled in the art.
The content of the invention
For above shortcomings in the prior art, the present invention provides a kind of Chinese medicine fodder for improving porkling resistance against diseases Additive and preparation method thereof, the Chinese herbal feed additive is had no toxic side effect, and pig bacterial disease can be prevented and treated by being added in feed, Strengthen the Abwehrkraft des Koepers of pig.
To achieve these goals, the present invention is realized using following technical scheme：
A kind of Chinese herbal feed additive for improving porkling resistance against diseases, is made up of following raw material by weight：Arbor-vitae 10-25 parts of leaf, 10-35 parts of Asiatic plantain, 10-30 parts of reticulate millettia, 15-35 parts of the fruit of Cherokee rose, 3-10 parts of cloves, 20-40 parts of the bark of eucommia, hardship 6-18 parts of 15-35 parts of ginseng, 6-12 parts of Poria cocos and teasel root.
Preferably, the Chinese herbal feed additive of described raising porkling resistance against diseases, by following original by weight Material is made：22 parts of cacumen biotae, 29 parts of Asiatic plantain, 19 parts of reticulate millettia, 31 parts of the fruit of Cherokee rose, 8 parts of cloves, 32 parts of the bark of eucommia, 30 parts of kuh-seng, 15 parts of 10 parts of Poria cocos and teasel root.
In addition, present invention also offers a kind of preparation side of the Chinese herbal feed additive of described raising porkling resistance against diseases Method, comprises the following steps：
(1) each taste medicine is weighed by weight, and cacumen biotae, reticulate millettia, the fruit of Cherokee rose, kuh-seng, 5 kinds of Chinese medicine materials of teasel root are mixed Close, add after running water, immersion 1-3h, it is boiled with high heat, then with after slow fire infusion 30-60min, decoction is poured out, Chinese medicine is obtained Decoction liquor；
(2) powder will be ground into after Asiatic plantain, cloves, Poria cocos, 4 kinds of Chinese medicine material drying of the bark of eucommia, crosses 60-120 mesh sieves, obtain Herb powder；
(3) decocting for Chinese herbal medicine liquid obtained by step (1) and the herb powder obtained by step (2) are mixed, stirred, passed through Expanded, Chinese medicinal granule is made in granulation；
(4) Chinese medicinal granule is produced into the Chinese herbal feed additive for improving porkling resistance against diseases by 100g/ bags of packing.
Preferably, the addition of running water is 6-10 times of 10 kinds of Chinese medicine material weight in step (1).
Present invention also offers the application method of the Chinese herbal feed additive of the raising porkling resistance against diseases, when in use, It is 1 with quality of the fodder ratio:100.
Compared with prior art, the present invention has the advantages that：
(1) Chinese herbal feed additive of raising porkling resistance against diseases of the invention be compounded by plurality of Chinese component and Into using pure Chinese medicine composition, having no toxic side effect.
(2) Chinese herbal feed additive of raising porkling resistance against diseases of the invention, especially right for pig bacterial disease The bacteriosises such as the red dysentery of brickpox, swine plague, swine escherichia coli, pig have good prevention and treatment effect.
(3) the Chinese herbal feed additive raw material of raising porkling resistance against diseases of the invention is easy to get, and medicine source is wide, convenient material drawing, It can promote the use of.
Embodiment
The embodiment of the present invention is described in detail with reference to specific embodiment, it is to be understood that of the invention Protection domain do not limited by embodiment.
Embodiment 1：
A kind of Chinese herbal feed additive for improving porkling resistance against diseases, is made up of following raw material by weight：Arbor-vitae 10 parts of leaf, 10 parts of Asiatic plantain, 10 parts of reticulate millettia, 15 parts of the fruit of Cherokee rose, 3 parts of cloves, 20 parts of the bark of eucommia, 15 parts of kuh-seng, 6 parts of Poria cocos and continuous It is disconnected 6 parts.
The preparation method of the Chinese herbal feed additive of described raising porkling resistance against diseases, comprises the following steps：
(1) each taste medicine is weighed by weight, and cacumen biotae, reticulate millettia, the fruit of Cherokee rose, kuh-seng, 5 kinds of Chinese medicine materials of teasel root are mixed Close, add after running water, immersion 1h, it is boiled with high heat, then with after slow fire infusion 30min, decoction is poured out, decocting for Chinese herbal medicine is obtained Liquid；The addition of running water is 6 times of 10 kinds of Chinese medicine material weight；
(2) powder will be ground into after Asiatic plantain, cloves, Poria cocos, 4 kinds of Chinese medicine material drying of the bark of eucommia, crosses 60 mesh sieves, obtain Chinese medicine Powder；
(3) decocting for Chinese herbal medicine liquid obtained by step (1) and the herb powder obtained by step (2) are mixed, stirred, passed through Expanded, Chinese medicinal granule is made in granulation；
(4) Chinese medicinal granule is produced into the Chinese herbal feed additive for improving porkling resistance against diseases by 100g/ bags of packing.
Embodiment 2：
A kind of Chinese herbal feed additive for improving porkling resistance against diseases, is made up of following raw material by weight：Arbor-vitae 25 parts of leaf, 35 parts of Asiatic plantain, 30 parts of reticulate millettia, 35 parts of the fruit of Cherokee rose, 10 parts of cloves, 40 parts of the bark of eucommia, 35 parts of kuh-seng, 12 parts of Poria cocos and 18 parts of teasel root.
The preparation method of the Chinese herbal feed additive of described raising porkling resistance against diseases, comprises the following steps：
(1) each taste medicine is weighed by weight, and cacumen biotae, reticulate millettia, the fruit of Cherokee rose, kuh-seng, 5 kinds of Chinese medicine materials of teasel root are mixed Close, add after running water, immersion 3h, it is boiled with high heat, then with after slow fire infusion 60min, decoction is poured out, decocting for Chinese herbal medicine is obtained Liquid；The addition of running water is 10 times of 10 kinds of Chinese medicine material weight；
(2) powder will be ground into after Asiatic plantain, cloves, Poria cocos, 4 kinds of Chinese medicine material drying of the bark of eucommia, 120 mesh sieves be crossed, in obtaining Medicinal powder end；
(3) decocting for Chinese herbal medicine liquid obtained by step (1) and the herb powder obtained by step (2) are mixed, stirred, passed through Expanded, Chinese medicinal granule is made in granulation；
(4) Chinese medicinal granule is produced into the Chinese herbal feed additive for improving porkling resistance against diseases by 100g/ bags of packing.
Embodiment 3：
A kind of Chinese herbal feed additive for improving porkling resistance against diseases, is made up of following raw material by weight：Arbor-vitae 20 parts of leaf, 20 parts of Asiatic plantain, 20 parts of reticulate millettia, 20 parts of the fruit of Cherokee rose, 5 parts of cloves, 30 parts of the bark of eucommia, 20 parts of kuh-seng, 10 parts of Poria cocos and 12 parts of teasel root.
The preparation method of the Chinese herbal feed additive of described raising porkling resistance against diseases, comprises the following steps：
(1) each taste medicine is weighed by weight, and cacumen biotae, reticulate millettia, the fruit of Cherokee rose, kuh-seng, 5 kinds of Chinese medicine materials of teasel root are mixed Close, add after running water, immersion 1-3h, it is boiled with high heat, then with after slow fire infusion 45min, decoction is poured out, decocting for Chinese herbal medicine is obtained Liquid；The addition of running water is 8 times of 10 kinds of Chinese medicine material weight；
(2) powder will be ground into after Asiatic plantain, cloves, Poria cocos, 4 kinds of Chinese medicine material drying of the bark of eucommia, crosses 80 mesh sieves, obtain Chinese medicine Powder；
(3) decocting for Chinese herbal medicine liquid obtained by step (1) and the herb powder obtained by step (2) are mixed, stirred, passed through Expanded, Chinese medicinal granule is made in granulation；
(4) Chinese medicinal granule is produced into the Chinese herbal feed additive for improving porkling resistance against diseases by 100g/ bags of packing.
Embodiment 4：The Chinese herbal feed additive of the raising porkling resistance against diseases of the present invention is in preventing and treating pig bacterial disease Test effect
The effect analysis of the anti-brickpox of Chinese herbal feed additive of 4.1 present invention
The normal diet of this experimental example is commercially available conventional feed, is consisted of the following components in percentage by weight：Corn 70.15%th, dregs of beans 22.0%, fish meal 5.0%, calcium monohydrogen phosphate 1%, stone flour 0.55%, salt 0.3% and Hui Feng piglet premixes 1%.
Experimental method：Weanling pig 500 is chosen, wherein 300 respectively as the isolated rearing of test group 1,2,3,100 Control group isolated rearing is only used as blank group isolated rearing, 100.Control group and blank group only feed normal diet, examination 1,2,3 isolated rearings of group are tested, the embodiment 1 of addition 8%, 2,3 Chinese medicine preparations+normal diet are fed respectively.Feeding manner is used After free choice feeding, free water, 24h, erysipelas bacterium liquid after test group, the weanling pig intramuscular injection inoculation dilution of control group is taken, it is empty White group is not inoculated with, and records 120h disease conditions, as a result as shown in table 1.
The effect analysis of the anti-brickpox of Chinese herbal feed additive of the present invention of table 1
The effect analysis of the anti-swine plague of Chinese herbal feed additive of 4.2 present invention
Experimental method is with test example 1, and difference is, pig after this test example test group weanling pig intramuscular injection inoculation dilution Lung epidemic disease bacterium liquid, the results are shown in Table 2.
The effect analysis of the anti-swine plague of Chinese herbal feed additive of the present invention of table 2
The effect analysis of the Chinese herbal feed additive anti colibacillosis of pigs of 4.3 present invention
Experimental method is with test example 1, and difference is, pig after this test example test group weanling pig intramuscular injection inoculation dilution E. coli bacteria liquid, the results are shown in Table 3.
The effect analysis of the Chinese herbal feed additive anti colibacillosis of pigs of the present invention of table 3
The effect analysis of the red dysentery disease of the anti-pig of Chinese herbal feed additive of 4.4 present invention
Experimental method is with test example 1, and difference is, pig after this test example test group weanling pig intramuscular injection inoculation dilution Red dysentery bacterium liquid, the results are shown in Table 4.
The effect analysis of the red dysentery of the anti-pig of Chinese herbal feed additive of the present invention of table 4
The test group 1-3 after the Chinese herbal feed additive of the present invention is with the addition of it can be seen from table 1-4 relative to not adding Plus the control group of Chinese herbal feed additive of the present invention, pig bacteria resistance disease ability significantly improves, the effect of anti-pig bacterial disease Fruit is substantially.
It is foregoing to the present invention specific illustrative embodiment description be in order to illustrate and illustration purpose.These descriptions It is not wishing to limit the invention to disclosed precise forms, and it will be apparent that according to above-mentioned teaching, can be much changed And change.The purpose of selecting and describing the exemplary embodiment is that explaining that the certain principles and its reality of the present invention should With so that those skilled in the art can realize and using the present invention a variety of exemplaries and A variety of selections and change.The scope of the present invention is intended to be limited by claims and its equivalents.

Claims (4)

1. a kind of Chinese herbal feed additive for improving porkling resistance against diseases, it is characterised in that by following raw material by weight It is made：10-25 parts of cacumen biotae, 10-35 parts of Asiatic plantain, 10-30 parts of reticulate millettia, 15-35 parts of the fruit of Cherokee rose, 3-10 parts of cloves, the bark of eucommia 6-18 parts of 20-40 parts, 15-35 parts of kuh-seng, 6-12 parts of Poria cocos and teasel root.
2. the Chinese herbal feed additive according to claim 1 for improving porkling resistance against diseases, it is characterised in that by by weight The following raw material of part ratio is made：22 parts of cacumen biotae, 29 parts of Asiatic plantain, 19 parts of reticulate millettia, 31 parts of the fruit of Cherokee rose, 8 parts of cloves, the bark of eucommia 32 Part, 30 parts of kuh-seng, 10 parts of Poria cocos and 15 parts of teasel root.
3. the preparation method of the Chinese herbal feed additive according to claim 1 or 2 for improving porkling resistance against diseases, its feature It is, comprises the following steps：
(1) each taste medicine is weighed by weight, and cacumen biotae, reticulate millettia, the fruit of Cherokee rose, kuh-seng, 5 kinds of Chinese medicine materials of teasel root are mixed, Add after running water, immersion 1-3h, it is boiled with high heat, then with after slow fire infusion 30-60min, decoction is poured out, decocting for Chinese herbal medicine is obtained Liquid；
(2) powder will be ground into after Asiatic plantain, cloves, Poria cocos, 4 kinds of Chinese medicine material drying of the bark of eucommia, crosses 60-120 mesh sieves, obtain Chinese medicine Powder；
(3) decocting for Chinese herbal medicine liquid obtained by step (1) and the herb powder obtained by step (2) are mixed, stirred, by swollen Change, Chinese medicinal granule is made in granulation；
(4) Chinese medicinal granule is produced into the Chinese herbal feed additive for improving porkling resistance against diseases by 100g/ bags of packing.
4. the preparation method of the Chinese herbal feed additive according to claim 3 for improving porkling resistance against diseases, its feature exists In the addition of running water is 6-10 times of 10 kinds of Chinese medicine material weight in step (1).
CN201710239307.0A 2017-04-13 2017-04-13 A kind of Chinese herbal feed additive for improving porkling resistance against diseases and preparation method thereof Pending CN107137476A (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103355499A (en) * 2013-07-29 2013-10-23 广南(湛江)家丰饲料有限公司 Feed addictive for improving pork quality and increasing efficiency of feed utilization and preparation thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103355499A (en) * 2013-07-29 2013-10-23 广南(湛江)家丰饲料有限公司 Feed addictive for improving pork quality and increasing efficiency of feed utilization and preparation thereof

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* Cited by examiner, † Cited by third party
Title
许小琴: "消肿解毒饮的体外抑菌及利尿试验", 《中兽医医药杂志》 *

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