CN107114781A - It is a kind of for health food of liver protection and preparation method thereof - Google Patents
It is a kind of for health food of liver protection and preparation method thereof Download PDFInfo
- Publication number
- CN107114781A CN107114781A CN201710146272.6A CN201710146272A CN107114781A CN 107114781 A CN107114781 A CN 107114781A CN 201710146272 A CN201710146272 A CN 201710146272A CN 107114781 A CN107114781 A CN 107114781A
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- CN
- China
- Prior art keywords
- health food
- root
- liver protection
- liver
- thick paste
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Classifications
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- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
Abstract
The invention provides a kind of health food for liver protection, it is prepared from by hawthorn, the red sage root, the fruit of Chinese magnoliavine, the Radix Astragali and the root of kudzu vine.Invention also provides preparation method：The fruit of Chinese magnoliavine, the red sage root, the root of kudzu vine, plus ethanol heating and refluxing extraction, merging filtrate are taken, thick paste is condensed into；Hawthorn, the Radix Astragali are taken, is added water to cook, merging filtrate is condensed into thick paste, mixes, is dried under reduced pressure with above-mentioned thick paste, powder makes pellet into fine powder, ethanol, whole grain, tabletting, film coating.The health food for the liver protection that the present invention is provided have substantially protection liver effect, with promoting blood circulationization is long-pending, air making-up and spleen enlivening, ascending the clear and descending the turbid effect, it is adaptable to the crowd of alcoholic liver injury.Tabules can be prepared into, is easy to taking and carrying for patient.
Description
Technical field
It is the health food for liver protection prepared by raw material of Chinese herbal medicine the invention belongs to the field of Chinese medicines.
Background technology
AML (alcoholic liver disease, ALD) refers to due to liver caused by excessive alcohol intake
Infringement and its a series of lesions, still turn into one of common disease of serious harm public health, and be in worldwide
Ascendant trend year by year.With China's dietary structure and living-pattern preservation, ALD illness rates also constantly increase, to our people
Healthy and social development constitutes serious threat.Its main clinical characteristics is nausea and vomiting, jaundice, liver enlargement and pressure
Bitterly, extensive necrosis of liver cells even liver failure and UGB etc. can be induced during serious excessive drinking.It is a large amount of or disposable
Excessive consumption of alcohol, can directly result in acute alcoholism and seriously infringement liver, kidney, brain et al. body vitals.Therefore, have
Alcohol is referred to as " chronic hepatotoxin " by people.The underlying cause of death of ALD patient is portal hypertension, hepatic encephalopathy, ascites, liver kidney synthesis
Seek peace esophagus fundus ventricularis varication etc..Recently there is scholar's discovery, the enhancing of ALD Platelets activation capability is easier to blood occur small
Plate is reduced, and causes hemorrhagic disease.The even serious short-term death rate of ALD patient is up to more than 35%.
But ALD generation development is a process slowly hidden, often patient is difficult to discover in itself, once occur
There is hepatic injury and have just arrived the situation that exception occurs in liver function in symptom or discovery, should belong to the stage of alcoholic hepatitis.Typically
For, ALD includes mild ALD (mild alcoholic injury, MAI), alcoholic fatty liver (alcoholic fatty
Liver, AFL), alcoholic hepatitis (alcohol hepatitis, AH), alcoholic fibrosis (alcoholichepatic
Fibrosis, AHF) and 5 types such as alcoholic cirrhosis (alcoholic cirrhosis, AC).Alcoholic more than 90%
Easily suffer from fatty liver, 10%~35% develops into alcoholic hepatitis, the chronic wine-head that there are about 8%~20% develops into hepatic sclerosis,
Even result in liver cancer.It is estimated that the U.S. in 1993 there are about 15,300,000 people excessive drinking, there is ten thousand people more than 200 with alcoholic liver patient,
Annual to have 2.6 ten thousand people to die from hepatic sclerosis, the alcoholic that wherein at least 40% is perhaps up to 90% has excessive drinking history.In China with me
State's dietary structure and living-pattern preservation, ALD illness rates are also improved constantly.The current ALD of China incidence of disease is compared with 20th century 80
30 times were added before age, morbidity patient population is only second to virus hepatitis.The existing wine folk law 1.6 hundred million of China, wherein 90,000,000 people
Long-term alcohol；The Drinking rate of population is up to 59.5%, and year drink absolute alcohol amount is calculated as 3.6L per capita, and rises year by year, to China
People's health and social development constitute serious threat.
Current doctor trained in Western medicine there is no active drug, and ALD is still based on abstinence from alcohol and nutritional support in the treatment, and traditional Chinese medicine has its own
Advantage, according to the cause of disease and clinical characters, be attributed to the categories such as " getting sick from drinking too much wine ", " wine ruffian ", " wine subcutaneous ulcer ", " wine distension ".The traditional Chinese medical science is recognized
Be poisonous product for, wine, it is sweet, bitter, pungent, it is warm-natured, cross drink must impairment of the spleen liver and gall and cause disease.Therefore its etiology and pathogenesis is to drink
Excessively cause the turbid interior life of spleen injury, retention of damp-heat in the interior, the dysfunction of the spleen in transport, functional activity of QI being not smooth, qi-blood disharmony, phlegm, qi and blood phlegm to be fought to tie and cause
Disease.Chinese medicine AML is more based on promoting blood circulation and removing blood stasis, clearing damp and promoting diuresis, regulating qi-flowing for eliminating phlegm, and according to the not same order of illness
Section and different diseases add with antipyretic, qi-restoratives medicine etc., that is, follow theory of traditional Chinese medical science to alcoholic liver injury control principle, pass through promoting blood circulation
Change product, air making-up and spleen enlivening, ascending the clear and descending the turbid effect reaches the defencive function to liver.
With social progress and economic development, the mankind are to own health growing interest and attention.China has integration of drinking and medicinal herbs
Long history, its unique health care culture and product not only conform with mankind's back to nature, reach raising quality of life, prolong
Slow aging, the hope of increase life expectancy, and with advantages such as small, the effect mitigations of toxic side effect, be at home and abroad increasingly subject to
Pay attention to.Since the nineties, the healthy consumption of global resident rises year by year, and the demand to health food is very vigorous.With economy
Development and growth in the living standard, the dietary trend of people is changed into auxotype from originally simply having adequate food and clothing, existing forward direction
Health develops.In China, with the improvement of living condition, excessive drinking number increases, simultaneously because domestic hepatopathy is main by hepatitis
Virus causes, and hepatitis viruse carrier's is more, may mask actually alcohol as the hepatopathy of the cause of disease, therefore,
It is most important for AML prevention and health care.With deepening continuously for recognizing alcoholic liver injury, people are to Alcoholic
The protective awareness of hepatic injury gradually strengthens, and in the market also occurs in that some alcohol-decomposing beverages and health food in succession, such as sea Wang Jin cups,
Three strange liver invigorating health teas etc., but it is relative compared to the health functional food such as immunological regulation, auxiliary reducing blood lipid, anti-aging, antifatigue
It is fewer, therefore hawthorn and shizandra berry, the red sage root, Pueraria lobota have selected according to the pathogenesis of alcoholic liver injury, the feature of preventing and treating of Chinese medicine
Root, the Radix Astragali five tastes can be used for the material of health food, constitute the formula for auxiliary protection liver, health food-ginseng stilbene is made
Five tastes liver protection piece.
The content of the invention
It is used for liver-protective health food the invention provides one kind, the same of medication is carried out to alcoholic liver injury patient
Shi Jinhang auxiliary treatments, and reduce the toxic side effect of medicine, it is intended to it is clinically more ALD patient services, for Alcoholic
Hepatic injury crowd is significant.
The health food of the present invention has selected the raw material available for health food：Hawthorn, the red sage root, the fruit of Chinese magnoliavine, the Radix Astragali and Pueraria lobota
Root.
Hawthorn has food digesting stomach fortifying, the function of scattered stasis.For meat stagnation, gastral cavilty is swollen, diarrhea dysentery abdominal pain, hemostasis warp
Close, postpartum stasis, confidant sting, dissipate gas pain, hyperlipidemia.It mainly contains the compositions such as flavones, organic acid, tannin.Have
Reducing blood lipid increases coronary flow, improves myocardial ischemia, and decompression suppresses platelet aggregation, protects vascular endothelial cell, and enhancing is immune
Function, anti-aging, antibacterial improves the effect such as gastrointestinal function.
The effect of red sage root has mental-tranquilization, cool blood to disappear carbuncle, apocenosis myogenic, is mainly used in irregular menstruation, dysmenorrhoea, Amenorrhea,
Postpartum blood stasis, chest and abdomen or limbs pain due to blood stasis, carbuncle sore tumefacting virus, vexed insomnia etc..Mainly contain the fat-soluble chemical combination such as quinone, ketone
Thing, such as：Salvia miltiorrhiza bge I, tanshinone IIA, red sage root quinone, the water soluble ingredient such as danshensu.Followed with cerebral thrombus, improvement coronary artery is suppressed
Ring, improvement myocardial ischemia, improvement microcirculation, reducing blood lipid, anti arteriosclerosis, improvement hemorheological property, suppression blood coagulation, resist oxygen lack,
Anti-inflammatory is antibacterial, suppresses hepatic injury, anti-hepatic fibrosis, antitumor to wait effect.
The fruit of Chinese magnoliavine have moistening lung, nourshing kidney, hidroschesis, antidiarrheal, it is puckery smart the effect of.Cure mainly cough and asthma, spontaneous perspiration, night sweat, seminal emission, long
Rush down, neurasthenia etc..Contain lignin, triterpene acids and lactone constituents.With suppression hepatic injury, anti-oxidant, anti-aging, rush
Enter the effects such as protein synthesis, removing toxic substances, enhancing immunologic function, improvement cardiac function, antiulcer, resisting stress.
The Radix Astragali has invigorating qi for strengthening superficies, and pus draining and toxin expelling, diuresis myogenic is mainly used in treatment deficiency of vital energy weak, rush down prolapse of the anus for a long time, spontaneous perspiration, water
It is swollen, the prolapse of uterus, the card such as the long disunion of chronic rephrilis protinuria, diabetes, the open sore part.Mainly contain polysaccharide, saponin(e, flavonoids into
Point, with enhancing immunologic function, antiviral, improvement myocardial damage, protection cardiac muscle cell, anti-inflammatory, hypoglycemic isoreactivity.
The root of kudzu vine have expelling pathogenic factors from muscles and skin, bring down a fever, promote the production of body fluid, promoting eruption, rising Yang, antidiarrheal the effects such as.For fever caused by exogenous pathogens, headache Xiang Qiang, mouth
Yearningly, quench one's thirst, measles without adequate eruption, hot dysentery diarrhea etc..Mainly contain osajin, saponin component.With resisting myocardial ischemia, improve the heart
Function, expansion blood vessel, anti-hypertension, anti-arrhythmia, hypoglycemic, reducing blood lipid, antipyretic, anticancer, removing toxic substances, it is anti-oxidant, relieve the effect of alcohol, resist
The effects such as anoxic, suppression platelet aggregation, liver protection.
By above-mentioned five kinds of combinations of substances together, by promoting blood circulation and removing blood stasis, air making-up and spleen enlivening, ascending the clear and descending the turbid function reaches the present invention
Protective effect to liver.
Specifically, a kind of health food (ginseng stilbene five tastes liver protection piece) for liver protection of the present invention, is by following former
Material is prepared from：Hawthorn, the red sage root, the fruit of Chinese magnoliavine, the Radix Astragali and the root of kudzu vine.
A kind of health food for liver protection of the present invention is preferably prepared from by the raw material of following parts by weight：
Hawthorn 500-600 parts by weight fruit of Chinese magnoliavine 150-250 parts by weight g
The heavy part Radix Astragali 200-300 parts by weight of red sage root 350-450
Root of kudzu vine 300-400 parts by weight.
A kind of health food for liver protection of the present invention is more preferably prepared from by the raw material of following parts by weight：
Hawthorn 550-600 parts by weight fruit of Chinese magnoliavine 180-230 parts by weight
The heavy part Radix Astragali 220-250 parts by weight of red sage root 380-420
Root of kudzu vine 330-380 parts by weight.
The invention provides a kind of preparation method of the health food of liver protection, it comprises the following steps：
(1) pretreatment of supplementary material
1. hawthorn pre-treating method is：Remove impurity and the core come off.
2. fruit of Chinese magnoliavine pre-treating method is：Remove impurity.
3. red sage root pre-treating method is：Impurity and residual stem are removed, is cleaned, is run through, cut sheet, is dried.
4. Radix Astragali pre-treating method is：Impurity is removed, size is separated, clean, run through, cut sheet, dried.
5. root of kudzu vine pre-treating method is：Impurity is removed, is cleaned, is run through, cut sheet, dry.
(2) production technology：The fruit of Chinese magnoliavine, the red sage root, the root of kudzu vine are taken, plus 5-7 times is measured 60-80% ethanol heating and refluxing extraction two to three
Secondary, each 2-5 hours, 80-100 mesh filtration, merging filtrate reclaims ethanol, and it is 1.15~1.20 (50 to be concentrated into relative density
DEG C survey) thick paste；Hawthorn, the Radix Astragali are taken, plus 8-10 times is measured decocting and boiled two to three times, is decocted 2-4 hours every time, the filter of 80-100 mesh
Cross, merging filtrate, be concentrated into the thick paste that relative density is 1.15~1.20, mixed with above-mentioned thick paste, 70-85 DEG C is dried under reduced pressure,
Powder is made pellet into fine powder, 80-95% ethanol, and 40-50 DEG C, piece is made in whole grain, tabletting, film coating, and packing is produced.
The health food (ginseng stilbene five tastes liver protection piece) for the liver protection that the present invention is provided has substantially protection liver effect.
The health food of liver protection prepared by the present invention, with promoting blood circulationization is long-pending, air making-up and spleen enlivening, ascending the clear and descending the turbid effect, be applicable
In the crowd of alcoholic liver injury.Various formulations can be prepared into, Tabules is preferably prepared to, are easy to taking and taking for patient
Band.
Brief description of the drawings
Fig. 1 is production technology sketch
Wherein, A, B represent different clean ranks, A respectively：Represent general clean level, B：Represent 300,000 grades.
Embodiment
Production technology sketch, is shown in Fig. 1
Preparation method embodiment
Formula：Hawthorn 556g, fruit of Chinese magnoliavine 167g, red sage root 389g, Radix Astragali 222g, the root of kudzu vine 333g, common 1667g.
Total amount is made：1000, every 0.6g are made (equivalent to 1.667g crude drugs).
Instructions of taking：Three times a day, 3 tablets once
Preparation method：
(1) fruit of Chinese magnoliavine 167g, red sage root 389g, root of kudzu vine 333g are taken, plus 5 times of 70% ethanol heating and refluxing extractions of amount are twice, often
Secondary 2 hours, 100 mesh filtration, merging filtrate reclaimed ethanol, was concentrated into thick paste of the relative density for 1.15~1.20 (50 DEG C of surveys)
It is standby；
(2) take hawthorn 556g, Radix Astragali 222g, plus 8 times of amount decoctings to boil secondary, decoct 2 hours every time, the filtration of 100 mesh merges
Filtrate, concentration causes relative density standby for the thick paste of 1.15~1.20 (50 DEG C)；
(3) thick paste obtained by (1) (2) is mixed, 85 DEG C are dried under reduced pressure, powder is into fine powder, and the pelleting of 95% ethanol is 50 DEG C, whole
Grain, tabletting, film coating produces the health food of (ginseng stilbene five tastes liver protection piece) liver protection.
The beneficial effect for inventing the health food is expanded on further below by way of test example, these test examples include
The auxiliary protection liver function experiment of health food (hereinafter referred to as joining stilbene five tastes liver protection piece) of the present invention.
Influence of the test example to Alcoholic Hepatic Injury
1st, test material
1.1 animal：KM mouse, SPF grades, purchased from Changchun Institute of Biological Products Co., Ltd., quality certification number：
201500011043。
1.2 medicines and reagent：Join stilbene five tastes liver protection piece, provided by the court formulation room；Ethanol, Beijing Chemical Plant, lot number：
20160128.Triglycerides (TG), lot number：20151124；MDA (MDA), lot number：20151013；Reduced glutathione
(GSH), lot number：20151124, Bioengineering Research Institute is built up in Nanjing.
1.3 instrument：UV-5100 type ultraviolet-visible photometers, Shanghai Yuan Xi Instrument Ltd..
2nd, test method and result
Mouse 50 is taken, animal is adapted to after environment, is randomly divided into 5 groups：Blank control group, model group joins stilbene five tastes liver protection
Piece 5.0,2.5, the 1.25g raw materials/dosage administration groups of kg tri-.Daily gavage is administered once, and successive administration 45 days is weighed weekly
Once, different dosing time changes of weight situation is observed.1h after last dose, 50% second is given by gavage of each group animal
Alcohol, 12ml/kg, blank control group gavages same volume distilled water, fasting afterwards 6 hours, puts to death animal and takes in liver, detection hepatic tissue
The change of MDA, TG, GSH content.It the results are shown in Table 1,2.
Influence of the table 1 to alcoholic liver injury mouse weight
Influence of the table 2 to alcoholic liver injury murine liver tissue MDA, TG, GSH content
Note：Δ is compared P with model group<0.05, Δ Δ is compared P with model group<0.01,
Δ Δ Δ is compared P with model group<0.001；* P is compared with control group<0.05,
* is compared P with control group<0.01, * * * are compared P with control group<0.001, similarly hereinafter.
As a result visible, ginseng stilbene five tastes liver protection piece has no significant effect to different time mouse weight；Alcoholic can substantially be suppressed
Hepatic injury murine liver tissue MDA, TG content, raises GSH contents, shows that ginseng stilbene five tastes liver protection piece has obvious hepatoprotective effect.
Inventive formulation orally can substantially suppress alcoholic liver injury murine liver tissue MDA, TG content, and rise GSH contains
Amount, has no significant effect to different time mouse weight, shows that it has significant protective effect to alcoholic liver injury.It is applied to
The crowd of long-term alcohol is one has the health food of auxiliary protection liver function well.
Above example, only for the purpose of description, is not intended to limit the invention, it is all the spirit and principles in the present invention it
Interior, any modification, equivalent substitution and improvements made etc. should be included in the scope of the protection.
Claims (11)
1. a kind of health food for liver protection, is prepared from by hawthorn, the red sage root, the fruit of Chinese magnoliavine, the Radix Astragali and the root of kudzu vine.
2. a kind of health food for liver protection according to claim 1, it is characterised in that by the raw material of following parts by weight
It is prepared from：
Hawthorn 500-600 parts by weight fruit of Chinese magnoliavine 150-250 parts by weight
The heavy part Radix Astragali 200-300 parts by weight of red sage root 350-450
Root of kudzu vine 300-400 parts by weight.
3. a kind of health food for liver protection according to claim 1, it is characterised in that by the raw material of following parts by weight
It is prepared from：
Hawthorn 550-600 parts by weight fruit of Chinese magnoliavine 180-230 parts by weight
The heavy part Radix Astragali 220-250 parts by weight of red sage root 380-420
Root of kudzu vine 330-380 parts by weight.
4. a kind of health food for liver protection according to claim 1, it is characterised in that by the raw material of following parts by weight
It is prepared from：
Hawthorn 556g, fruit of Chinese magnoliavine 167g, red sage root 389g, Radix Astragali 222g, root of kudzu vine 333g.
5. a kind of health food for liver protection according to claim 1-4, it is characterised in that be prepared into various formulations.
6. a kind of health food for liver protection according to claim 1-4, it is characterised in that be prepared into Tabules.
7. according to a kind of preparation method of any described health food for liver protection in claim 1-4, it includes as follows
Step：
The pretreatment of supplementary material：
1. hawthorn pre-treating method is：Remove impurity and the core come off；
2. fruit of Chinese magnoliavine pre-treating method is：Remove impurity；
3. red sage root pre-treating method is：Impurity and residual stem are removed, is cleaned, is run through, cut sheet, is dried；
4. Radix Astragali pre-treating method is：Impurity is removed, size is separated, clean, run through, cut sheet, dried；
5. root of kudzu vine pre-treating method is：Impurity is removed, is cleaned, is run through, cut sheet, dry.
8. a kind of preparation method of health food for liver protection according to claim 7, it comprises the following steps：
The fruit of Chinese magnoliavine, the red sage root, the root of kudzu vine are taken, plus 5-7 times is measured 60-80% ethanol heating and refluxing extraction two to three times times, each 2-5 is small
When, 80-100 mesh filtration, merging filtrate reclaims ethanol, is concentrated into thick paste of the relative density for 1.15~1.20 (50 DEG C of surveys)；Take
Hawthorn, the Radix Astragali, plus 8-10 times measured decocting and boiled two to three times, is decocted 2-4 hour every time, 80-100 mesh filtration, merging filtrate is concentrated
To the thick paste that relative density is 1.15~1.20, mixed with above-mentioned thick paste, 70-85 DEG C is dried under reduced pressure, powder is into fine powder, 80-95%
Ethanol makes pellet, and 40-50 DEG C, piece is made in whole grain, tabletting, film coating, packing, produces.
9. a kind of preparation method of health food for liver protection according to claim 8, it comprises the following steps：
(1) fruit of Chinese magnoliavine, the red sage root, the root of kudzu vine are taken, plus 5 times of 70% ethanol heating and refluxing extractions of amount are twice, 2 hours every time, the filter of 100 mesh
Cross, merging filtrate, reclaim ethanol, the thick paste for being concentrated into relative density for 1.15~1.20 (50 DEG C of surveys) is standby；
(2) take hawthorn, the Radix Astragali, plus 8 times of amount decoctings to boil secondary, decoct 2 hours every time, 100 mesh filtration, merging filtrate, concentration is caused
Relative density is standby for the thick paste of 1.15~1.20 (50 DEG C)；
(3) thick paste obtained by (1) (2) is mixed, 85 DEG C are dried under reduced pressure, powder makes pellet into fine powder, 95% ethanol, 50 DEG C, whole grain, pressure
Piece, film coating produces the health food of liver protection.
10. a kind of preparation method of health food for liver protection according to claim 7, it comprises the following steps：
(1) fruit of Chinese magnoliavine 167g, red sage root 389g, root of kudzu vine 333g are taken, plus 5 times of 70% ethanol heating and refluxing extractions of amount are twice, 2 is small every time
When, 100 mesh filtration, merging filtrate reclaims ethanol, and the thick paste for being concentrated into relative density for 1.15~1.20 (50 DEG C of surveys) is standby；
(2) take hawthorn 556g, Radix Astragali 222g, plus 8 times of amount decoctings to boil secondary, decoct 2 hours every time, the filtration of 100 mesh merges filter
Liquid, concentration causes relative density standby for the thick paste of 1.15~1.20 (50 DEG C)；
(3) thick paste obtained by (1) (2) is mixed, 85 DEG C are dried under reduced pressure, powder makes pellet into fine powder, 95% ethanol, 50 DEG C, whole grain, pressure
Piece, film coating produces the health food of liver protection.
11. according to any system in any described a kind of health food and claim 7-9 for liver protection in claim 1-6
Application of the health food for liver protection that Preparation Method is prepared in prevention and treatment alcoholic liver injury.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN109045238A (en) * | 2018-10-31 | 2018-12-21 | 牛恩波 | There is one kind Tongmai Huoxue to dissipate the stasis of blood, and the traditional Chinese powder medicine of member is returned in invigorating the spleen righting |
| CN112790388A (en) * | 2021-01-29 | 2021-05-14 | 杨洋 | Preparation method of fructus alpiniae oxyphyllae and radix puerariae tablet candy |
| CN112841383A (en) * | 2021-01-29 | 2021-05-28 | 杨洋 | Formula of fructus alpiniae oxyphyllae and radix puerariae tablet candy |
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| CN1685913A (en) * | 2005-04-28 | 2005-10-26 | 郭博 | Body building tea bag and its preparation method |
| CN1850217A (en) * | 2006-01-28 | 2006-10-25 | 吉林敖东药业集团延吉股份有限公司 | Compounded preparation for treating fatty liver and preparing method |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1685913A (en) * | 2005-04-28 | 2005-10-26 | 郭博 | Body building tea bag and its preparation method |
| CN1850217A (en) * | 2006-01-28 | 2006-10-25 | 吉林敖东药业集团延吉股份有限公司 | Compounded preparation for treating fatty liver and preparing method |
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| CN109045238A (en) * | 2018-10-31 | 2018-12-21 | 牛恩波 | There is one kind Tongmai Huoxue to dissipate the stasis of blood, and the traditional Chinese powder medicine of member is returned in invigorating the spleen righting |
| CN112790388A (en) * | 2021-01-29 | 2021-05-14 | 杨洋 | Preparation method of fructus alpiniae oxyphyllae and radix puerariae tablet candy |
| CN112841383A (en) * | 2021-01-29 | 2021-05-28 | 杨洋 | Formula of fructus alpiniae oxyphyllae and radix puerariae tablet candy |
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