CN107109485B - 用于多重捕获反应的通用阻断寡聚物系统和改进的杂交捕获的方法 - Google Patents

用于多重捕获反应的通用阻断寡聚物系统和改进的杂交捕获的方法 Download PDF

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CN107109485B
CN107109485B CN201580066291.7A CN201580066291A CN107109485B CN 107109485 B CN107109485 B CN 107109485B CN 201580066291 A CN201580066291 A CN 201580066291A CN 107109485 B CN107109485 B CN 107109485B
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CN107109485A (zh
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E·奥利瓦瑞斯
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Invitae Corp
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CN201580066291.7A 2014-10-10 2015-10-08 用于多重捕获反应的通用阻断寡聚物系统和改进的杂交捕获的方法 Expired - Fee Related CN107109485B (zh)

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Application Number Priority Date Filing Date Title
US201462062612P 2014-10-10 2014-10-10
US201462062616P 2014-10-10 2014-10-10
US62/062,616 2014-10-10
US62/062,612 2014-10-10
PCT/IB2015/057679 WO2016055956A1 (en) 2014-10-10 2015-10-08 Universal blocking oligo system and improved hybridization capture methods for multiplexed capture reactions

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CN107109485A CN107109485A (zh) 2017-08-29
CN107109485B true CN107109485B (zh) 2020-12-08

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US (1) US10648103B2 (https=)
EP (1) EP3204518B1 (https=)
JP (1) JP6722179B2 (https=)
CN (1) CN107109485B (https=)
CA (1) CA2964069A1 (https=)
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WO2016126882A1 (en) 2015-02-04 2016-08-11 Twist Bioscience Corporation Methods and devices for de novo oligonucleic acid assembly
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KR20180050411A (ko) 2015-09-18 2018-05-14 트위스트 바이오사이언스 코포레이션 올리고핵산 변이체 라이브러리 및 그의 합성
KR102794025B1 (ko) 2015-09-22 2025-04-09 트위스트 바이오사이언스 코포레이션 핵산 합성을 위한 가요성 기판
CN115920796A (zh) 2015-12-01 2023-04-07 特韦斯特生物科学公司 功能化表面及其制备
JP6854340B2 (ja) 2016-08-22 2021-04-07 ツイスト バイオサイエンス コーポレーション デノボ合成された核酸ライブラリ
US10417457B2 (en) 2016-09-21 2019-09-17 Twist Bioscience Corporation Nucleic acid based data storage
KR102514213B1 (ko) 2016-12-16 2023-03-27 트위스트 바이오사이언스 코포레이션 면역 시냅스의 변이체 라이브러리 및 그의 합성
CN110892485B (zh) 2017-02-22 2024-03-22 特韦斯特生物科学公司 基于核酸的数据存储
WO2018170169A1 (en) 2017-03-15 2018-09-20 Twist Bioscience Corporation Variant libraries of the immunological synapse and synthesis thereof
US10696965B2 (en) 2017-06-12 2020-06-30 Twist Bioscience Corporation Methods for seamless nucleic acid assembly
WO2018231864A1 (en) 2017-06-12 2018-12-20 Twist Bioscience Corporation Methods for seamless nucleic acid assembly
CN111566125A (zh) 2017-09-11 2020-08-21 特韦斯特生物科学公司 Gpcr结合蛋白及其合成
CN111565834B (zh) 2017-10-20 2022-08-26 特韦斯特生物科学公司 用于多核苷酸合成的加热的纳米孔
KR102804057B1 (ko) 2018-01-04 2025-05-07 트위스트 바이오사이언스 코포레이션 Dna 기반 디지털 정보 저장
CA3100739A1 (en) 2018-05-18 2019-11-21 Twist Bioscience Corporation Polynucleotides, reagents, and methods for nucleic acid hybridization
US20190365645A1 (en) * 2018-05-31 2019-12-05 Massachusetts Institute Of Technology Drug delivery articles for gram-level dosing
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CN113766930B (zh) 2019-02-26 2025-07-22 特韦斯特生物科学公司 Glp1受体的变异核酸文库
CA3131691A1 (en) 2019-02-26 2020-09-03 Twist Bioscience Corporation Variant nucleic acid libraries for antibody optimization
AU2020298294A1 (en) 2019-06-21 2022-02-17 Twist Bioscience Corporation Barcode-based nucleic acid sequence assembly
WO2020259678A1 (zh) * 2019-06-26 2020-12-30 南京金斯瑞生物科技有限公司 一种含有阻断物的寡核苷酸
WO2021061842A1 (en) 2019-09-23 2021-04-01 Twist Bioscience Corporation Variant nucleic acid libraries for single domain antibodies
JP2022548309A (ja) 2019-09-23 2022-11-17 ツイスト バイオサイエンス コーポレーション Ｃｒｔｈ２のバリアント核酸ライブラリー
IL293670A (en) 2019-12-09 2022-08-01 Twist Bioscience Corp Variable nucleic acid libraries for adenosine receptors
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CN111961711A (zh) * 2020-08-31 2020-11-20 伯科生物科技有限公司 用于靶向测序的通用杂交增强剂及方法
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IL251661B (en) 2021-12-01
EP3204518B1 (en) 2019-07-10
CN107109485A (zh) 2017-08-29
EP3204518A1 (en) 2017-08-16
JP2017537609A (ja) 2017-12-21
EP3204518A4 (en) 2018-03-21
US20170218537A1 (en) 2017-08-03
IL251661A0 (en) 2017-06-29
WO2016055956A1 (en) 2016-04-14
CA2964069A1 (en) 2016-04-14
JP6722179B2 (ja) 2020-07-15
US10648103B2 (en) 2020-05-12

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