CN107109483B - 一种修饰模板双链多核苷酸的方法 - Google Patents

一种修饰模板双链多核苷酸的方法 Download PDF

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CN107109483B
CN107109483B CN201580062575.9A CN201580062575A CN107109483B CN 107109483 B CN107109483 B CN 107109483B CN 201580062575 A CN201580062575 A CN 201580062575A CN 107109483 B CN107109483 B CN 107109483B
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詹姆斯·怀特
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    • G01N33/48721—Investigating individual macromolecules, e.g. by translocation through nanopores
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    • C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
    • C12Q2525/30—Oligonucleotides characterised by their secondary structure
    • C12Q2525/301—Hairpin oligonucleotides
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    • C12Q2565/00—Nucleic acid analysis characterised by mode or means of detection
    • C12Q2565/60—Detection means characterised by use of a special device
    • C12Q2565/607—Detection means characterised by use of a special device being a sensor, e.g. electrode

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CN201580062575.9A 2014-10-14 2015-02-18 一种修饰模板双链多核苷酸的方法 Active CN107109483B (zh)

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GBGB1418159.8A GB201418159D0 (en) 2014-10-14 2014-10-14 Method
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PCT/GB2015/050461 WO2016059363A1 (en) 2014-10-14 2015-02-18 Method

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EP (1) EP3207152B1 (https=)
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CN104039979B (zh) 2011-10-21 2016-08-24 牛津纳米孔技术公司 使用孔和Hel308解旋酶表征目标多核苷酸的酶方法
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GB201907244D0 (en) * 2019-05-22 2019-07-03 Oxford Nanopore Tech Ltd Method
GB201917060D0 (en) * 2019-11-22 2020-01-08 Oxford Nanopore Tech Ltd Method
KR20220133999A (ko) * 2020-01-31 2022-10-05 타이리스 테라뷰틱스, 에스.엘. 변형된 뉴클레오티드들을 갖는 닫힌 선형 dna
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CN119095960A (zh) 2022-05-18 2024-12-06 牛津纳米孔科技公开有限公司 用于核酸提取和纯化的组合物和方法
CN118241319A (zh) * 2022-12-22 2024-06-25 北京齐碳科技有限公司 测序文库的制备方法
WO2025067293A1 (zh) * 2023-09-27 2025-04-03 北京齐碳科技有限公司 解旋酶及其应用
WO2025241167A1 (zh) * 2024-05-24 2025-11-27 深圳华大生命科学研究院 测序缓冲液和纳米孔捕获待测核酸序列的方法

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