CN107095966B - Striae gravidarum repair gel - Google Patents

Striae gravidarum repair gel Download PDF

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CN107095966B
CN107095966B CN201710437306.7A CN201710437306A CN107095966B CN 107095966 B CN107095966 B CN 107095966B CN 201710437306 A CN201710437306 A CN 201710437306A CN 107095966 B CN107095966 B CN 107095966B
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striae gravidarum
blood
rhizoma polygonati
repair gel
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CN107095966A (en
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潘夏军
罗明余
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Shanghai Kangyang Biological Technology Co ltd
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/062—Ascomycota
    • A61K36/066—Clavicipitaceae
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539—Scutellaria (skullcap)
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/756—Phellodendron, e.g. corktree
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels

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Abstract

The invention discloses a striae gravidarum repair gel, which belongs to the technical field of medical dressings and is prepared from the following raw materials in parts by weight: 10-18 parts of cordyceps sinensis, 8-14 parts of golden cypress, 8-14 parts of rhizoma polygonati, 6-12 parts of scutellaria baicalensis, 6-12 parts of cortex moutan, 6-12 parts of dragon's blood, 8-14 parts of angelica sinensis, 8-14 parts of rhodiola rosea, 8-14 parts of bletilla striata and 6-12 parts of tea polyphenol. Aiming at the grain repair of new and old striae gravidarum, the invention adopts a radio frequency instrument to destroy the original damaged grains, utilizes the striae gravidarum repair gel to permeate into the lower part of the corium layer, stimulates the recombination and regeneration of broken elastic fibers and collagen fibers, and the nutrition in the body is conveyed to the epidermis layer through the collagen fibers to form virtuous cycle regeneration.

Description

Striae gravidarum repair gel
Technical Field
The invention belongs to the technical field of medical dressings, and particularly relates to striae gravidarum repair gel.
Background
The striae gravidarum is mainly formed by that the striae gravidarum is influenced by hormone in the gestation period, the elastic fibers and the collagen fibers of the skin are damaged or broken to different degrees due to the expansion of the abdomen, the skin becomes thin and thin, and the skin of the abdominal wall can have pink or purple wavy patterns with different widths and lengths; after delivery, these patterns gradually disappear, leaving white or silvery-white, shiny scar lines, i.e. stretch marks. The scars are caused by the damage of physical, chemical and other factors and act on the skin soft tissues of the human body, so that the skin soft tissues are seriously damaged and cannot be completely repaired by self; the fibrous tissue replaces and repairs the left local symptoms which affect the appearance and the function.
At present, the repair of striae gravidarum in the medical and American fields at home and abroad is always a worldwide problem, and is generally solved by using laser dot matrix, skin grafting, micro-needle damage, skin grinding, growth factor growth, filling and the like in clinic, the methods only can play a role in improving and desalting, and cannot really and effectively repair fibrous tissues of a dermis layer broken due to pregnancy expansion, form the autonomous circulation metabolism growth of epidermis nutrients, and finally rebound to the original state.
Disclosure of Invention
The invention aims to solve the technical problem of providing a striae gravidarum repair gel which has the effects of inhibiting scar hyperplasia and lightening pigment, so that the original lines are restored to the normal skin state.
In order to solve the technical problems, the invention adopts the technical scheme that: the striae gravidarum repair gel is characterized by being prepared from the following raw materials in parts by weight: 10-18 parts of cordyceps sinensis, 8-14 parts of golden cypress, 8-14 parts of rhizoma polygonati, 6-12 parts of scutellaria baicalensis, 6-12 parts of cortex moutan, 6-12 parts of dragon's blood, 8-14 parts of angelica sinensis, 8-14 parts of rhodiola rosea, 8-14 parts of bletilla striata and 6-12 parts of tea polyphenol.
Further, 10-16 parts of cordyceps sinensis, 8-12 parts of golden cypress, 8-12 parts of rhizoma polygonati, 6-10 parts of scutellaria baicalensis, 6-10 parts of cortex moutan, 6-10 parts of dragon's blood, 8-12 parts of angelica sinensis, 8-12 parts of rhodiola rosea, 8-12 parts of bletilla striata and 6-10 parts of tea polyphenol.
Further, 12-16 parts of cordyceps sinensis, 10-12 parts of golden cypress, 10-12 parts of rhizoma polygonati, 8-10 parts of scutellaria baicalensis, 8-10 parts of cortex moutan, 8-10 parts of dragon's blood, 10-12 parts of angelica sinensis, 10-12 parts of rhodiola rosea, 10-12 parts of bletilla striata and 8-10 parts of tea polyphenol.
The invention has the beneficial effects that: the invention provides a striae gravidarum repair gel, aiming at repairing the lines of new and old striae gravidarum, a radio frequency instrument is adopted to destroy the original damaged lines, the striae gravidarum repair gel is permeated into the lower part of the corium layer to stimulate the recombination and regeneration of broken elastic fibers and collagen fibers, and the nutrition in the body is conveyed to the epidermis layer through the collagen fibers to form virtuous cycle regeneration.
Detailed Description
The technical solutions in the embodiments of the present invention are clearly and completely described below, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1:
a striae gravidarum repair gel is prepared from the following raw materials, by weight, 10g of cordyceps sinensis, 8g of golden cypress, 8g of rhizoma polygonati, 6g of scutellaria baicalensis, 6g of cortex moutan, 6g of dragon's blood, 8g of angelica sinensis, 8g of rhodiola rosea, 8g of bletilla striata and 6g of tea polyphenol.
The Cordyceps mainly contains Cordyceps extract, cordycepic acid, adenosine and polysaccharide; the Cordyceps sinensis essence can inhibit growth of bacteria such as streptococcus, Bacillus anthracis, etc., is anticancer active substance, and has good regulating effect on endocrine system and nervous system of human body; cordycepic acid can change human microcirculation; cordyceps polysaccharide is an immunomodulator, and can enhance the resistance of organism to virus and parasite. Therefore, the cordyceps sinensis is added to play an antifungal role, so that the immune system can be regulated, and the metabolic growth of cells can be accelerated.
Cortex Phellodendri has antibacterial effect, and berberine is used as antibacterial effective component of cortex Phellodendri, so its pharmacological action is substantially similar to that of Coptidis rhizoma, but its content is lower than that of Coptidis rhizoma. The in vitro test has effective or strong inhibiting effect on Staphylococcus aureus, pneumococcus, diphtheria bacillus, Streptococcus viridis, Shigella dysenteriae (except Sonne), hemolytic streptococcus, meningococcus, Vibrio cholerae, and Bacillus anthracis; it also has inhibitory effect on Bacillus subtilis, Bordetella pertussis, and tetanus bacillus. Therefore, the gel is added with the phellodendron bark to have the effects of resisting bacteria, detoxifying and treating sore.
Experiments show that the rhizoma polygonati water extract (1: 320) has the inhibition effect on typhoid bacillus, staphylococcus aureus and acid-fast bacillus, and 2 percent of rhizoma polygonati has the inhibition effect on common pathogenic fungi to different degrees in a Sasa medium; rhizoma Polygonati has antioxidant effect, and rhizoma Polygonati decoction has concentration of 20%, is fed to mice per 13ml, and is continued for 27 days to increase mouse liver superoxide dismutase (SOD) activity and reduce myocardial lipofuscin content; rhizoma Polygonati has antiaging effect, and is decocted with 20% concentration for soaking folium Mori to feed silkworm, and has effect in prolonging silkworm larva stage; rhizoma Polygonati has antiviral effect. Therefore, the rhizoma polygonati is added to play a role in resisting bacteria and resisting oxidation.
Scutellariae radix has effect in inhibiting pathogenic dermatophytes. Baicalein can inhibit acute inflammatory reaction. Inhibiting exudation swelling and capillary permeability increase of inflammation model. The gel is added with Scutellariae radix to make it have antifungal effect.
Cortex moutan has effects of clearing heat and cooling blood, and is related to pharmacological actions such as antibacterial, antiinflammatory, antiallergic, sedative hypnotic, anticonvulsant, etc., and effects of promoting blood circulation and removing blood stasis is related to effects of resisting platelet aggregation, changing hemorheology, resisting heart and brain ischemia, and resisting atherosclerosis. Cortex moutan can be added to promote blood circulation and remove blood stasis.
The dragon's blood has the functions of eliminating blood stasis, relieving pain, stopping bleeding and promoting granulation. The dragon's blood added into the gel can play a good role in removing blood stasis and promoting tissue regeneration.
The radix Angelicae sinensis has antiinflammatory and antibacterial effects, and the radix Angelicae sinensis decoction has slight inhibitory effect on Escherichia coli, typhoid and paratyphoid bacillus, dysentery bacillus, proteus bacillus, and diphtheria bacillus in test tube. The Chinese angelica can remove free radicals, and ferulic acid in the Chinese angelica has the effects of resisting lipid peroxidation, directly eliminating the free radicals, inhibiting oxidation reaction and free radical reaction, and can be combined with biological membrane phospholipid to protect membrane lipid from resisting damage of the free radicals to tissues; the angelica has good curative effects on eliminating stasis and detumescence in the swollen sore period and nourishing blood and promoting tissue regeneration in the ulcer period.
The rhodiola rosea can tonify qi, activate blood, promote blood circulation and relieve pain, is suitable for chest stuffiness and pains, palpitation, shortness of breath, mental fatigue and hypodynamia, and laziness in speaking caused by qi deficiency and blood stasis, and has the functions of tonifying qi and reducing swelling by adding the rhodiola rosea.
Bletilla striata has good effects of maintaining beauty and keeping young, bletilla striata contains rich starch, glucose, volatile oil, pituitous substances and other components, has the effects of whitening, removing freckles, astringing, stopping bleeding, diminishing swelling and promoting tissue regeneration, is a good beautifying drug since ancient times, is known as 'whitening fairy', can eliminate traces left by acne on the face by external inunction, can moisten and whiten the skin, and makes the skin smooth like jade. Radix Angelicae Dahuricae can be added to promote astringency and granulation.
The tea polyphenol has strong functions of eliminating harmful free radicals, resisting aging, resisting bacteria, sterilizing and resisting oxidation, the oxidation resistance of the tea polyphenol is 4-6 times that of artificially synthesized antioxidants BHT and BHA, 6-7 times that of VE and 5-10 times that of VC, the dosage is small, the tea polyphenol can act after 0.01-0.03 percent, and the tea polyphenol has no potential toxic or side effect of the composition. The tea polyphenol is added to make the tea have the effects of bacteriostasis and antisepsis.
These materials were washed clean with clean water and dried by oven. The dried raw materials are put together, ground and crushed by a grinding body and mixed evenly. Sieving the mixed raw material powder with a 400-mesh sieve, and pouring the sieved medicinal material powder into a steel pot. Adding purified water into the steel pot to submerge the medicinal materials, and decocting at high temperature. Filtering and purifying the decocted medicinal materials, adding the medicinal oil for later use, and finally adding an emulsifier for emulsification treatment to prepare gel. The striae gravidarum repair gel has a strong cell growth effect, has the effects of perfectly inhibiting scar hyperplasia, quickly fading pigments and accelerating epidermal growth, and can replace the situation that the existing striae gravidarum repair items in the market can only be faded and improved.
Example 2:
a striae gravidarum repair gel is prepared from the following raw materials, by weight, 18g of cordyceps sinensis, 14g of golden cypress, 14g of rhizoma polygonati, 12g of scutellaria baicalensis, 12g of cortex moutan, 12g of dragon's blood, 14g of angelica sinensis, 14g of rhodiola rosea, 14g of bletilla striata and 12g of tea polyphenol. The preparation method is identical to that of example 1.
Example 3:
a striae gravidarum repair gel is prepared from the following raw materials, by weight, 12g of cordyceps sinensis, 10g of golden cypress, 10g of rhizoma polygonati, 8g of scutellaria baicalensis, 8g of cortex moutan, 8g of dragon's blood, 10g of angelica sinensis, 10g of rhodiola rosea, 10g of bletilla striata and 8g of tea polyphenol. The preparation method is identical to that of example 1.
Example 4:
a striae gravidarum repair gel is prepared from the following raw materials, by weight, 16g of cordyceps sinensis, 12g of golden cypress, 12g of rhizoma polygonati, 10g of scutellaria baicalensis, 10g of cortex moutan, 10g of dragon's blood, 12g of angelica sinensis, 12g of rhodiola rosea, 12g of bletilla striata and 10g of tea polyphenol. The preparation method is identical to that of example 1.
The following is an effect test of the striae gravidarum repair gel in example 1 of the invention, 55 cases of striae gravidarum are selected, the age is 25-50 years, one treatment course is 1-3 times different, the repair time is 4 months fastest, 12 months latest and 8 months or so on average. Firstly, a radio frequency instrument is adopted to destroy the original old damaged and atrophied lines, then the repairing gel is applied constantly every day, the striae gravidarum repairing gel is permeated into the lower part of the dermis to stimulate the recombination and regeneration of the broken elastic fibers and the collagen fibers, and the nutrition in the body is conveyed to the epidermis layer through the collagen fibers to form virtuous cycle regeneration. As a result: the epidermis grows more than 95% in 20 cases, the epidermis grows more than 80% in 35 cases, the epidermis is ineffective in 0 case, and the effective rate is 100%.
The above description is only for the specific embodiments of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art can easily conceive of the changes or substitutions within the technical scope of the present invention, and all the changes or substitutions should be covered within the scope of the present invention. Therefore, the protection scope of the present invention shall be subject to the protection scope of the appended claims.

Claims (3)

1. The striae gravidarum repair gel is characterized by being prepared from the following raw materials in parts by weight: 10-18 parts of cordyceps sinensis, 8-14 parts of golden cypress, 8-14 parts of rhizoma polygonati, 6-12 parts of scutellaria baicalensis, 6-12 parts of cortex moutan, 6-12 parts of dragon's blood, 8-14 parts of angelica sinensis, 8-14 parts of rhodiola rosea, 8-14 parts of bletilla striata and 6-12 parts of tea polyphenol.
2. The striae gravidarum repair gel according to claim 1, wherein: 10-16 parts of cordyceps sinensis, 8-12 parts of golden cypress, 8-12 parts of rhizoma polygonati, 6-10 parts of scutellaria baicalensis, 6-10 parts of cortex moutan, 6-10 parts of dragon's blood, 8-12 parts of angelica sinensis, 8-12 parts of rhodiola rosea, 8-12 parts of bletilla striata and 6-10 parts of tea polyphenol.
3. The striae gravidarum repair gel according to claim 1, wherein: 12-16 parts of cordyceps sinensis, 10-12 parts of golden cypress, 10-12 parts of rhizoma polygonati, 8-10 parts of scutellaria baicalensis, 8-10 parts of cortex moutan, 8-10 parts of dragon's blood, 10-12 parts of angelica sinensis, 10-12 parts of rhodiola rosea, 10-12 parts of bletilla striata and 8-10 parts of tea polyphenol.
CN201710437306.7A 2017-06-12 2017-06-12 Striae gravidarum repair gel Active CN107095966B (en)

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CN111514082A (en) * 2020-05-14 2020-08-11 深圳爱思得美容科技有限公司 Striae gravidarum repair composition and application method thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101810774A (en) * 2010-04-15 2010-08-25 罗明余 Striae gravidarum mesoblast herbal repair liquid and preparation method thereof
CN102178764A (en) * 2011-04-15 2011-09-14 谭进超 Traditional Chinese medicine preparation capable of effectively repairing striae of pregnancy and scars
CN102205055A (en) * 2011-06-09 2011-10-05 王明全 Medicament for repairing skin and preparation method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101810774A (en) * 2010-04-15 2010-08-25 罗明余 Striae gravidarum mesoblast herbal repair liquid and preparation method thereof
CN102178764A (en) * 2011-04-15 2011-09-14 谭进超 Traditional Chinese medicine preparation capable of effectively repairing striae of pregnancy and scars
CN102205055A (en) * 2011-06-09 2011-10-05 王明全 Medicament for repairing skin and preparation method thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
妊娠纹预防修复纯天然医用茶油;不详;《http://www.52bjw.cn/product-info/34536328.html》;20161231;1-3 *

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