CN107080707A - Sufficient ointment of a kind of high oil content moisturizing anticracking handguard and preparation method thereof - Google Patents
Sufficient ointment of a kind of high oil content moisturizing anticracking handguard and preparation method thereof Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
- A61K8/06—Emulsions
- A61K8/064—Water-in-oil emulsions, e.g. Water-in-silicone emulsions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/342—Alcohols having more than seven atoms in an unbroken chain
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
- A61K8/375—Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/925—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of animal origin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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Abstract
The invention discloses sufficient ointment of a kind of high oil content moisturizing anticracking handguard and preparation method thereof.The raw material composition of the sufficient ointment of moisturizing anticracking shield is 40~55 parts of natural plant grease, 10~15 parts of NMF, 5~10 parts of lanolin, 5~10 parts of glycerin monostearate, 0.2~5 part of emulsifying agent, 0.5~1 part of plants essential oil, 25~60 parts of deionized water, 5~10 parts of sodium lauroyl glutamate, 0.01~0.3 part of essence.The present invention is on the basis of existing moisturizing cream product, natural plant grease content is improved, is allowed to be emulsified by emulsifying agent with water, then volatilize moisture content, ensure the stable emulsifying performance of product, it is aided with lawn plant essential oil simultaneously, product is fine and smooth, for the foodcare that ftractures, with good emollient, spreadability, moisture retention, permeability, there is good bactericidal and bacteriostatic effect simultaneously, additive is stimulated without any skin, with good market application foreground.
Description
Technical field
The invention belongs to cosmetic technical field, and in particular to a kind of sufficient ointment of high oil content moisturizing anticracking handguard and its system
Preparation Method.
Background technology
Grease is the base stock for constituting cream kind cosmetics, mainly plays skin care, soft and smooth and moist etc..Grease can be
Skin surface formation hydrophobic film.While skin emolliency, lubrication and glossiness is assigned.It can also prevent to a certain extent
Only the intrusion of harmful environmental material and resist the invasion and attack from nature many factors.According to the similar principle that mixes, grease can also
The oil-soluble dirt of skin surface is dissolved, so as to be used for as main composition in the cleaning products of skin surface.Grease can
To suppress the evaporation of moisture content, prevent chapped skin, make dry skin and hardening cuticula again water and, make cuticula recover it is soft
Soft elasticity.The content of grease is general not over 20% in current cosmetics cream kind product, more than fat content 20%
Product, its preparation technology does not have emulsifying technology substantially, that is, does not enter water-filling oil emulsification, and is directly added into vaseline, beeswax
Deng being thickened or being solidified, product spread is poor, and oil immersion goes out substantially.
Rhagadia manus et pedis is a kind of winter common skin disease, and winter is cold, and foot plantar smegma liquid is reduced, and skin is done
Dry, skin keratin is thickened, and is followed the string, and is easily chapped when extremity movement.The present invention is for existing prevention, treatment brothers' chap
Split the not enough of product and protect sufficient ointment and preparation method thereof, the product vegetable fat content there is provided a kind of high oil content moisturizing anticracking
More than 40%, prepared through emulsifying process, product is fine and smooth, for the foodcare that ftractures, with good emollient, spreadability, moisturizing
Property, permeability, while have good bactericidal and bacteriostatic effect, additive is stimulated without any skin, and similar technique is had no at present
Utilize part moisture content in whipping process to volatilize in relevant report, the technology, water is played oil-water emulsion effect initial stage in emulsification, and
In the later stage, part is volatilized again, it is ensured that product fine and smooth and stably.
The content of the invention
Or in view of the above-mentioned deficiencies in the prior art, it is an object of the present invention to not enough in existing cream product oil content, or
Without emulsification, the bad and inconvenient shortcoming of using effect, by first by oil-water emulsion, after by moisture evaporation, prepare one kind
With fat content is high, product exquisiteness is stable, at the same sterilization, humectation moisture-keeping efficacy be used for prevent, treat the complete of rhagadia manus et pedis
New product.
Another object of the present invention is to provide a kind of method for preparing the sufficient ointment of high oil content moisturizing anticracking handguard.
The purpose of the present invention is achieved by the following technical programs.
Unless otherwise indicated, percentage of the present invention is percetage by weight.
A kind of sufficient ointment of high oil content moisturizing anticracking handguard, the weight of its raw material composition is as follows:Crude vegetal
40~55 parts of fat, 10~15 parts of glycerine, 10~15 parts of NMF, 5~10 parts of lanolin, glycerin monostearate 5~
10 parts, 0.5~3 part of emulsifying agent, 1~5 part of cetostearyl alcohol, 0.5~1 part of plants essential oil, 25~35 parts of deionized water, bay
5~10 parts of acyl sodium glutamate, 0.01~0.3 part of essence, 0.01~0.3 part of preservative.
Described natural plant grease is jojoba oil, wheat-germ oil, grape-kernel oil, avocado oil, aloe, tea seed
One kind in oil.
Described NMF is in hyaluronic acid, trehalose, amino acid humectant, erythritol, NMF
It is a kind of.
Described emulsifying agent is one kind in emulsifying agent 328, emulsifying agent 338.
Described plants essential oil is in Geranium Essential, Peppermint essential oil, Lavender, Rosemary Oil, tea tree ethereal oil
One kind.
Described preservative is that one of methyl hydroxybenzoate, ethylparaben, propylben are planted.
The sufficient ointment preparation method of the art high oil content moisturizing anticracking handguard, comprises the steps:
(1)Glycerine, natural plant grease, plants essential oil, lanolin, NMF are mixed, 80~95 DEG C of heating stirrings are uniform;
(2)Sodium lauroyl glutamate, emulsifying agent, cetostearyl alcohol, glycerin monostearate, 70 are separately added into deionized water
~80 DEG C of heating, and stir;
(3)By step(1)With(2)Gains are placed in homogenous disperse mulser, set shearing force as 500~1500rpm, are risen
Temperature is to 90 DEG C, and constant temperature stirs 40~60min;
(4)Homogenous disperse emulsification cover is risen into 1~2cm, temperature, shearing force are constant, and constant temperature, which stirs 20~40min, makes part water
Divide volatilization;
(5)60~40 DEG C are cooled to, preservative is added, temperature, shearing force are constant, 10~30min of mixing time;
(6)Essence is added, reduction shearing force is 500~1000rpm, is cooled to room temperature;
(7)By step(5)Still aging 20~28 hours of gains, produce product.
Relative to prior art, the present invention has advantages below:
1st, emulsified and volatilization moisture content technology by water oil, realize the emulsifying technology of high fat content cream, product exquisiteness is stable.
2nd, product has good emollient, spreadability, moisture retention, permeability, while having good bactericidal effect
Really, it is stable preparation process, reliable respectively into playing each self-applying.
Embodiment
By specific examples presented below and typical Application Example can further be well understood the present invention but
They are not limitation of the invention.
Embodiment 1
(1)100g glycerine, 400g jojoba oils, 5g tea tree ethereal oils, 50g lanolin, the 90 DEG C of heating of 100g hyaluronic acids, and stir
Mix uniform;
(2)Be separately added into 250g deionized waters 50g sodium lauroyl glutamates, 5g emulsifying agents 328,10g cetostearyl alcohols,
50g glycerin monostearates, 70 DEG C of heating, and stir;
(3)By step(1)With(2)Gains are placed in homogenous disperse mulser, are set shearing force as 600rpm, are warming up to 90
DEG C, constant temperature stirring 40min;
(4)Homogenous disperse emulsification cover is risen into 1~2cm, temperature, shearing force are constant, constant temperature stirring 20min waves part moisture
Hair;
(5)40 DEG C are cooled to, 10g methyl hydroxybenzoates are added, temperature, shearing force are constant, mixing time 10min;
(6)10g essence is added, reduction shearing force is 500rpm, is cooled to room temperature;
(7)By step(6)Still aging 20 hours of gains, produce product.
Embodiment 2
(1)120g glycerine, 450g wheat-germ oils, 6g Geranium Essentials, 60g lanolin, the 90 DEG C of heating of 100g hyaluronic acids,
And stir;
(2)Be separately added into 300g deionized waters 60g sodium lauroyl glutamates, 10g emulsifying agents 338,20g cetostearyl alcohols,
60g glycerin monostearates, 75 DEG C of heating, and stir;
(3)By step(1)With(2)Gains are placed in homogenous disperse mulser, are set shearing force as 800rpm, are warming up to 90
DEG C, constant temperature stirring 45min;
(4)Homogenous disperse emulsification cover is risen into 1~2cm, temperature, shearing force are constant, constant temperature stirring 30min waves part moisture
Hair;
(5)40 DEG C are cooled to, 10g ethylparabens are added, temperature, shearing force are constant, mixing time 25min;
(6)15g essence is added, reduction shearing force is 600rpm, is cooled to room temperature;
(7)By step(6)Still aging 24 hours of gains, produce product.
Embodiment 3
(1)110g glycerine, 500g grape-kernel oils, 7g Peppermint essential oils, 70g lanolin, the 90 DEG C of heating of 100g hyaluronic acids, and stir
Mix uniform;
(2)Be separately added into 350g deionized waters 70g sodium lauroyl glutamates, 15g emulsifying agents 328,30g cetostearyl alcohols,
70g glycerin monostearates, 70 DEG C of heating, and stir;
(3)By step(1)With(2)Gains are placed in homogenous disperse mulser, are set shearing force as 1000rpm, are warming up to 90
DEG C, constant temperature stirring 50min;
(4)Homogenous disperse emulsification cover is risen into 1~2cm, temperature, shearing force are constant, constant temperature stirring 25min waves part moisture
Hair;
(5)40 DEG C are cooled to, 20g propylbens are added, temperature, shearing force are constant, mixing time 20min;
(6)20g essence is added, reduction shearing force is 700rpm, is cooled to room temperature;
(7)By step(6)Still aging 28 hours of gains, produce product.
Embodiment 4
(1)130g glycerine, 550g avocado oils, 8g Lavenders, 80g lanolin, the 90 DEG C of heating of 100g hyaluronic acids, and stir
Mix uniform;
(2)Be separately added into 280g deionized waters 80g sodium lauroyl glutamates, 20g emulsifying agents 338,40g cetostearyl alcohols,
80g glycerin monostearates, 80 DEG C of heating, and stir;
(3)By step(1)With(2)Gains are placed in homogenous disperse mulser, are set shearing force as 800rpm, are warming up to 90
DEG C, constant temperature stirring 55min;
(4)Homogenous disperse emulsification cover is risen into 1~2cm, temperature, shearing force are constant, constant temperature stirring 35min waves part moisture
Hair;
(5)40 DEG C are cooled to, 15g methyl hydroxybenzoates are added, temperature, shearing force are constant, mixing time 15min;
(6)25g essence is added, reduction shearing force is 600rpm, is cooled to room temperature;
(7)By step(6)Still aging 24 hours of gains, produce product.
Embodiment 5
(1)140g glycerine, 500g aloes, 9g Rosemary Oils, 90g lanolin, the 90 DEG C of heating of 100g hyaluronic acids, and stir
Mix uniform;
(2)Be separately added into 320g deionized waters 90g sodium lauroyl glutamates, 25g emulsifying agents 328,50g cetostearyl alcohols,
90g glycerin monostearates, 75 DEG C of heating, and stir;
(3)By step(1)With(2)Gains are placed in homogenous disperse mulser, are set shearing force as 1000rpm, are warming up to 90
DEG C, constant temperature stirring 60min;
(4)Homogenous disperse emulsification cover is risen into 1~2cm, temperature, shearing force are constant, constant temperature stirring 30min waves part moisture
Hair;
(5)40 DEG C are cooled to, 30g ethylparabens are added, temperature, shearing force are constant, mixing time 20min;
(6)30g essence is added, reduction shearing force is 1000rpm, is cooled to room temperature;
(7)By step(6)Still aging 28 hours of gains, produce product.
Embodiment 6
(1)150g glycerine, 450g camellia seed oils, 10g tea tree ethereal oils, 100g lanolin, the 90 DEG C of heating of 100g hyaluronic acids, and
Stir;
(2)Be separately added into 350g deionized waters 100g sodium lauroyl glutamates, 30g emulsifying agents 338,25g cetostearyl alcohols,
100g glycerin monostearates, 80 DEG C of heating, and stir;
(3)By step(1)With(2)Gains are placed in homogenous disperse mulser, are set shearing force as 1000rpm, are warming up to 90
DEG C, constant temperature stirring 60min;
(4)Homogenous disperse emulsification cover is risen into 1~2cm, temperature, shearing force are constant, constant temperature stirring 40min waves part moisture
Hair;
(5)40 DEG C are cooled to, 10g methyl hydroxybenzoates are added, temperature, shearing force are constant, mixing time 30min;
(6)10g essence is added, reduction shearing force is 800rpm, is cooled to room temperature;
(7)By step(6)Still aging 28 hours of gains, produce product.
The embodiment 1-6 products prepared are centrifuged, heat-resisting, low temperature resistant test, it the results are shown in Table 1.
The centrifugation of the high oil content moisturizing anticracking handguard of table 1 foot ointment, heat-resisting, low temperature resistant test
Result of the test shows, it is fine and smooth that the present invention prepares product appearance, by centrifugation, heat-resisting, low temperature resistant test, with centrifugation, it is heat-resisting,
Cold-resistant stability.
Product prepared by embodiment 1-6 is used for the safety evaluatio of skin, and one of method is exactly to carry out skin irritation
Experiment.The experiment can be carried out on animal or human body.200 ± 10g rat 5 is chosen, wherein female 2, male 3, are used
8% Na2S solution carries out depilation about 3cm in back to it2, taking a day off makes its stimulate the reaction caused by depilation recover normal.
Take 0.5g test samples to be spread evenly across after shaving part, 24h and observe skin whether there is rubescent, allergy, plays the phenomenons such as rash, observe result
It is shown in Table 2.Healthy volunteer 5, when carrying out skin irritation test to it, human arm or femoribus internus are coated on by test sample
Deng on soft skin surface, after the reaction of observation coating skin after 24h, observation the results are shown in Table 3.
The rat skin irritant experiment result of table 2
Note:Negative "-";It is positive(Rubescent, allergy plays rash, got blister)“+”.
The human body skin irritant experiment result of table 3
Note:Negative "-";It is positive(Rubescent, allergy plays rash, got blister)“+”.
The product prepared with embodiment 1-6 is to rat and human volunteer without skin irritatin, and product safety is effective.
Claims (7)
1. a kind of sufficient ointment of high oil content moisturizing anticracking handguard, the weight of its raw material composition is as follows:Natural plant grease
40~55 parts, 10~15 parts of glycerine, 10~15 parts of NMF, 5~10 parts of lanolin, glycerin monostearate 5~10
Part, 0.5~3 part of emulsifying agent, 1~5 part of cetostearyl alcohol, 0.5~1 part of plants essential oil, 25~35 parts of deionized water, lauroyl
5~10 parts of sodium glutamate, 0.01~0.3 part of essence, 0.01~0.3 part of preservative.
2. the sufficient ointment of high oil content moisturizing anticracking handguard according to claim 1, described natural plant grease for flash
One kind in bar oil, wheat-germ oil, grape-kernel oil, avocado oil, aloe, camellia seed oil.
3. the sufficient ointment of high oil content moisturizing anticracking shield according to claim 1, described NMF is hyaluronic acid, sea
One kind in algae sugar, amino acid humectant, erythritol, NMF.
4. the sufficient ointment of high oil content moisturizing anticracking handguard according to claim 1, described emulsifying agent is emulsifying agent 328,
One kind in emulsifying agent 338.
5. the sufficient ointment of high oil content moisturizing anticracking handguard according to claim 1, described plants essential oil is fish pelargonium essence
One kind in oil, Peppermint essential oil, Lavender, Rosemary Oil, tea tree ethereal oil.
6. the sufficient ointment of high oil content moisturizing anticracking handguard according to claim 1, described preservative is Metagin
One of ester, ethylparaben, propylben are planted.
7. preparing the sufficient ointment of art high oil content moisturizing anticracking handguard described in claim 1, its preparation method comprises the steps:
(1)Glycerine, natural plant grease, plants essential oil, lanolin, NMF are mixed, 80~95 DEG C of heating stirrings are uniform;
(2)Sodium lauroyl glutamate, emulsifying agent, cetostearyl alcohol, glycerin monostearate, 70 are separately added into deionized water
~80 DEG C of heating, and stir;
(3)By step(1)With(2)Gains are placed in homogenous disperse mulser, set shearing force as 500~1500rpm, are risen
Temperature is to 90 DEG C, and constant temperature stirs 40~60min;
(4)Homogenous disperse emulsification cover is risen into 1~2cm, temperature, shearing force are constant, and constant temperature, which stirs 20~40min, makes part water
Divide volatilization;
(5)60~40 DEG C are cooled to, preservative is added, temperature, shearing force are constant, 10~30min of mixing time;
(6)Essence is added, reduction shearing force is 500~1000rpm, is cooled to room temperature;
(7)By step(5)Still aging 20~28 hours of gains, produce product.
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Cited By (3)
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JP2019517998A (en) * | 2016-04-21 | 2019-06-27 | ユニリーバー・ナームローゼ・ベンノートシヤープ | Process for producing small droplet emulsions under low pressure |
CN112057391A (en) * | 2020-10-22 | 2020-12-11 | 南京泛成生物科技有限公司 | Moisturizing cream and preparation method thereof |
CN114762542A (en) * | 2021-05-27 | 2022-07-19 | 吉林省手足堂生物科技有限公司 | Multifunctional sock capable of preventing foot from cracking and application thereof |
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