CN107075457B - 培养具有腈水合酶活性的微生物的方法 - Google Patents

培养具有腈水合酶活性的微生物的方法 Download PDF

Info

Publication number
CN107075457B
CN107075457B CN201580050795.XA CN201580050795A CN107075457B CN 107075457 B CN107075457 B CN 107075457B CN 201580050795 A CN201580050795 A CN 201580050795A CN 107075457 B CN107075457 B CN 107075457B
Authority
CN
China
Prior art keywords
nitrile hydratase
acid
microorganism
organic acid
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201580050795.XA
Other languages
English (en)
Chinese (zh)
Other versions
CN107075457A (zh
Inventor
K·哈格
C·施瓦尔布
P·斯普洛特
P·奥德曼
K-U·鲍尔代纽斯
B·恩斯特
G·斯泰格尔曼
S·费赖尔
C·博尔施韦勒
M·G·布劳恩
J·道韦尔
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BASF SE
Original Assignee
BASF SE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BASF SE filed Critical BASF SE
Publication of CN107075457A publication Critical patent/CN107075457A/zh
Application granted granted Critical
Publication of CN107075457B publication Critical patent/CN107075457B/zh
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/38—Chemical stimulation of growth or activity by addition of chemical compounds which are not essential growth factors; Stimulation of growth by removal of a chemical compound
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y402/00—Carbon-oxygen lyases (4.2)
    • C12Y402/01—Hydro-lyases (4.2.1)
    • C12Y402/01084—Nitrile hydratase (4.2.1.84)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CN201580050795.XA 2014-09-30 2015-09-30 培养具有腈水合酶活性的微生物的方法 Active CN107075457B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP14187144 2014-09-30
EP14187144.2 2014-09-30
PCT/EP2015/072594 WO2016050861A1 (en) 2014-09-30 2015-09-30 Method of cultivating microorganisms having nitrile hydratase activity

Publications (2)

Publication Number Publication Date
CN107075457A CN107075457A (zh) 2017-08-18
CN107075457B true CN107075457B (zh) 2021-03-26

Family

ID=51730324

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201580050795.XA Active CN107075457B (zh) 2014-09-30 2015-09-30 培养具有腈水合酶活性的微生物的方法

Country Status (7)

Country Link
US (1) US20170260519A1 (enExample)
EP (1) EP3201316B1 (enExample)
JP (1) JP6714584B2 (enExample)
CN (1) CN107075457B (enExample)
ES (1) ES2784277T3 (enExample)
PL (1) PL3201316T3 (enExample)
WO (1) WO2016050861A1 (enExample)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2016235568B2 (en) 2015-03-26 2020-04-23 Basf Se Biocatalytic production of L-fucose
EA202091021A1 (ru) 2017-10-25 2020-09-14 Басф Се Способ получения водных растворов полиакриламида
WO2019081004A1 (en) 2017-10-25 2019-05-02 Basf Se PROCESS FOR PRODUCING AQUEOUS POLYACRYLAMIDE SOLUTIONS
WO2019081003A1 (en) 2017-10-25 2019-05-02 Basf Se PROCESS FOR PRODUCING AQUEOUS POLYACRYLAMIDE SOLUTIONS
WO2019081321A1 (en) 2017-10-25 2019-05-02 Basf Se PROCESS FOR PRODUCING AQUEOUS POLYACRYLAMIDE SOLUTIONS
CA3076553A1 (en) 2017-10-25 2019-05-02 Basf Se Process for producing aqueous polyacrylamide solutions
US11384177B2 (en) 2017-10-25 2022-07-12 Basf Se Process for producing aqueous polyacrylamide solutions
US11634516B2 (en) 2017-10-25 2023-04-25 Basf Se Process for producing aqueous polyacrylamide solutions
WO2019081008A1 (en) 2017-10-25 2019-05-02 Basf Se PROCESS FOR PRODUCING AQUEOUS ACRYLAMIDE SOLUTION
CA3112658A1 (en) 2018-10-18 2020-04-23 Basf Se Process of fracturing subterranean formations
WO2020079119A1 (en) 2018-10-18 2020-04-23 Basf Se Method of providing aqueous polyacrylamide concentrates
WO2020079124A1 (en) 2018-10-18 2020-04-23 Basf Se Process for producing aqueous polyacrylamide compositions
EA202191076A1 (ru) 2018-10-18 2021-08-03 Басф Се Способ получения водного концентрата полиакриламида
CN111334495B (zh) * 2020-03-12 2022-04-29 宜昌东阳光生化制药有限公司 制备右旋酰胺酮洛芬的方法
WO2023041515A2 (en) 2021-09-15 2023-03-23 Basf Se Method for preparing an aqueous (meth) acrylamide solution
CN120399985B (zh) * 2025-07-01 2025-09-09 云南省农业科学院农业环境资源研究所 一株泛菌ynk-fb0056及其应用

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1235978A (zh) * 1998-03-16 1999-11-24 三井化学株式会社 参与活化腈水合酶的蛋白以及编码它的基因
CN1571843A (zh) * 2001-03-02 2005-01-26 大赛璐化学工业株式会社 腈水合酶和生产酰胺的方法
WO2009009117A2 (en) * 2007-07-11 2009-01-15 Bioverdant, Inc. Chemoenzymatic processes for preparation of levetiracetam

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6083581A (ja) * 1983-10-13 1985-05-11 Hideaki Yamada シユ−ドモナス属細菌の培養法
JPH01171478A (ja) * 1987-12-26 1989-07-06 Res Assoc Util Of Light Oil ロドコッカス属細菌の培養方法
JPH07303491A (ja) * 1994-03-16 1995-11-21 Asahi Chem Ind Co Ltd 光学活性な酸アミドの製造法
JP2004254690A (ja) * 2003-02-03 2004-09-16 Nippon Soda Co Ltd Ｄｌ−メチオニンの製造法
GB0307026D0 (en) * 2003-03-27 2003-04-30 Rowett Res Inst Bacterial supplement
WO2008127997A1 (en) * 2007-04-12 2008-10-23 Wisconsin Alumni Research Foundation Enhanced protein expression using auto-induction media
JP4665066B1 (ja) * 2010-02-15 2011-04-06 住友商事株式会社 ブタノールの新規な生産方法
KR101586132B1 (ko) * 2011-06-07 2016-01-19 미쯔비시 레이온 가부시끼가이샤 개량형 니트릴 히드라타제
RU2520870C1 (ru) * 2012-12-27 2014-06-27 Кемира Оюй Штамм бактерий rhodococcus aetherivorans bkm ac-2610d - продуцент нитрилгидратазы, способ его культивирования и способ получения акриламида

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1235978A (zh) * 1998-03-16 1999-11-24 三井化学株式会社 参与活化腈水合酶的蛋白以及编码它的基因
CN1571843A (zh) * 2001-03-02 2005-01-26 大赛璐化学工业株式会社 腈水合酶和生产酰胺的方法
WO2009009117A2 (en) * 2007-07-11 2009-01-15 Bioverdant, Inc. Chemoenzymatic processes for preparation of levetiracetam

Also Published As

Publication number Publication date
JP6714584B2 (ja) 2020-06-24
US20170260519A1 (en) 2017-09-14
CN107075457A (zh) 2017-08-18
EP3201316B1 (en) 2020-02-19
EP3201316A1 (en) 2017-08-09
PL3201316T3 (pl) 2020-06-29
JP2017529849A (ja) 2017-10-12
ES2784277T3 (es) 2020-09-23
WO2016050861A1 (en) 2016-04-07

Similar Documents

Publication Publication Date Title
CN107075457B (zh) 培养具有腈水合酶活性的微生物的方法
EP3201348B2 (en) Method for preparing an aqueous acrylamide solution having a low acrylic acid concentration
CN107075494B (zh) 制备具有较少丙烯酸的酰胺化合物的手段和方法
WO2016050819A1 (en) Method for preparing an acrylamide solution having a low acrylic acid concentration
JP2017535249A5 (enExample)
WO2017055518A1 (en) Means and methods for producing an amide compound
EP3225694A1 (en) Method for the production of acrylamide by defined addition of the biocatalyst
US20220403426A1 (en) Method of storing a biocatalyst
EP3225693A1 (en) Method for preparing aqueous acrylamide solutions
WO2023183785A2 (en) Variant nitrile hydratases, microbia which express same, and use in amide synthesis

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant