CN107047585A - One kind is combined antifungal agricultural chemicals - Google Patents
One kind is combined antifungal agricultural chemicals Download PDFInfo
- Publication number
- CN107047585A CN107047585A CN201710440605.6A CN201710440605A CN107047585A CN 107047585 A CN107047585 A CN 107047585A CN 201710440605 A CN201710440605 A CN 201710440605A CN 107047585 A CN107047585 A CN 107047585A
- Authority
- CN
- China
- Prior art keywords
- formula
- plant
- formulas
- fungicide
- combined
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
- A01N47/10—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof
- A01N47/20—N-Aryl derivatives thereof
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
- A01N47/10—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof
- A01N47/18—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof containing a —O—CO—N< group, or a thio analogue thereof, directly attached to a heterocyclic or cycloaliphatic ring
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The present invention relates to a kind of compound fungicide of Synergistic, it includes Formulas I, the Fungicidal active ingredient of Formula II, and suppresses the composition that plant pathogenic fungi generation produces drug resistance for Formulas I and/or Formula II.It is described it is compound kill that safe and efficient, has a broad antifungal spectrum, fungus control effect are good, be particularly suitable for use in preventing and treating the various disease funguses infection of apple tree.
Description
Technical field
The invention belongs to technical field of pesticide, it is related to a kind of compound pesticide composition, and in particular to increase containing two kinds of collaborations
Imitate the composition pesticide of Fungicidal active ingredient.
Background technology
Plant infect disease in, the most species of fungal disease, account for the 70%~80% of whole plant diseases with
On.The fungal disease of apple belongs to widely distributed disease in China, not only harm is produced in field, due also to its latent infection is special
Property, fruit is endangered, yield reduction, fruit can be made to lose commodity value, loses very big, fruit industry production safety is had a strong impact on.It is as usual
The Major Fungus Diseases seen have：Rot, anthracnose, ring spot, powdery mildew, diplostomiasis, dry rot etc..
Due to fungus-caused plant disease most species, it is most universal, the mankind study plant pathogenic fungi earliest, most
It is detailed, so the bactericide species for being exclusively used in preventing and treating fungal disease so far is also most.In agricultural production process, with killing
Microbial inoculum preventing and treating fungal infection is faced with two large problems for a long time：One is that anti-fungus spectra is not wide enough, although researcher is devoted for years to
In research and development broad-spectrum antifungals, but because plant pathogenic fungi species is various, genetic background and form are highly broken up, therefore relatively
For the species of plant pathogenic fungi, even the antifungal agent of wide spectrum is also only applicable to wherein sub-fraction disease fungus
Preventing and treating.Two be that drug resistance fungal persistently occurs, and widely uses fungicide to control disease fungus for a long time in agricultural production, this year is
The drug resistance disease fungus of a variety of fungicides is directed to through having engendered, but the research and development speed of new fungicide is not much with
The generation speed of upper drug resistance fungal, it is impossible to meet the need for preventing and treating drug resistance disease fungus in production.
In agricultural production practice, it is to prevent and treat the common side of plant pathogenic fungi that different types of agricultural chemicals is carried out into compounding
Method.However, because pesticide variety is various, the compound scheme of different pesticide varieties, compounding effect are different, it is generally raw by agricultural
Production person compounds to different farm chemical ingredients, according to field using effect, and it is synergy plus and or antagonism to estimate certain compounding
Effect.The unordered abuse of fungicide not only causes the poorly efficient of fungus control, and is easy to the generation of inducible resistance fungi.
In most cases, fungicide compounding is all simple fungicidal effect superposition, and real Synergistic is then considerably less.
The content of the invention
For the above-mentioned problems in the prior art, the present invention provide it is a kind of be combined antifungal agricultural chemicals, its have safety,
Efficiently, has a broad antifungal spectrum, fungus control effect is good, be difficult induction produce drug-fast bacteria the features such as.
In a first aspect, the present invention provides a kind of compound antifungal agricultural chemicals with synergistic function, it is characterised in that bag
Fungicidal active ingredient containing Formulas I and Formula II,
And suppress the composition that plant pathogenic fungi generation produces drug resistance for Formulas I and/or Formula II.
It is pesticide corrosion 120 that suppression fungi of the present invention, which produces the composition for producing drug resistance for Formulas I and/or Formula II,.
It is of the present invention to be combined antifungal agricultural chemicals, Formulas I in its feature: the weight of Formula II this be 4-1: 1-4.
It is of the present invention to be combined antifungal agricultural chemicals, it is characterised in that the suppression fungi, which produces, is directed to Formulas I and/or Formula II
The content for producing the composition of drug resistance is 3-6%.
It is of the present invention to be combined antifungal agricultural chemicals, it is characterised in that the agricultural chemicals is aqua, pulvis, wettable powder, grain
Agent.
It is of the present invention to be combined antifungal agricultural chemicals, it is characterised in that the formula by weight containing 15% Formulas I, 30%
II, 4% pesticide corrosion 120.
Second aspect, the present invention also provides a kind of application method for being combined antifungal agricultural chemicals, it is characterised in that will be described multiple
Close antifungal agricultural chemicals to carry out after 1: 400 dilution with weakly acidic pH or faintly acid solvent, spray plant.
Plant of the present invention includes but is not limited to apple, pears, peach, grape etc..
The third aspect, the present invention also provides the purposes for being combined antifungal agricultural chemicals in preventing and treating plant fungal disease,
It is preferred for preventing and treating fruit tree fungal disease.
Plant of the present invention includes but is not limited to apple, pears, peach, grape etc.；Described plant fungal disease is excellent
Superior pathogenic fungi is elected as, such as sac fungus, basidiomycetes, Fungi Imperfecti.
Fourth aspect, the present invention also provides the compound antifungal agricultural chemicals in plant pathogenic fungi generation drug resistance is suppressed
Purposes.
Plant of the present invention includes but is not limited to apple, pears, peach, grape etc.；Described plant fungal disease is excellent
Superior pathogenic fungi is elected as, such as sac fungus, basidiomycetes, Fungi Imperfecti.
The present invention achieves following technique effect：
1. of the present invention be combined antifungal agricultural chemicals for high-efficiency low-toxicity formula, by 2 two kinds of fungicides containing phenyl ring of Formulas I and formula
Compounding generates synergistic function, can effectively control drug resistance plant pathogenic fungi.
2. compound antifungal agricultural chemicals of the present invention has further expanded antimicrobial spectrum by the compounding of two kinds of fungicides, right
Encountered pathogenic fungi has inhibitory action in current agricultural production practice so that agricultural producer is without specifically identifying disease fungus
Particular type, that is, be easy to use, decrease the abuse of fungicide.
3. of the present invention be combined the composition that antifungal agricultural chemicals contains suppression drug-fast bacteria generation, resistance can be avoided or reduced
The generation of bacterium, is applied to long-term use or single cropping is used for multiple times.
Embodiment
Below in conjunction with specific embodiment, the present invention is expanded on further.These embodiments be merely to illustrate the present invention and without
In limitation the scope of the present invention.The experimental method of unreceipted actual conditions in the following example, generally according to normal condition or is pressed
According to the condition proposed by manufacturer.Unless otherwise defined, all specialties used in text are ripe with this area with scientific words
Practice meaning known to personnel identical.In addition, any method similar or impartial to described content and material all can be applied to
In the inventive method.Preferable implementation described in text only presents a demonstration with material to be used.
Embodiment 1
Pathogen is gathered from the apple with rot, by being accredited as one plant of black skin shell bacterium, Formulas I and formula are identified with it
II Synergistic active action condition.
Using Toxicity Determination method, standard method NY/T1156.2-2006 is surveyed with reference to raw, using pastille culture medium method：
The decoction 6mL of each single dose and mixture series concentration is taken, addition is cooled in 45 DEG C of 54mL PDA culture medium, required for being made
The pastille culture medium flat board of final concentration.Then the object bacteria colony edge from culture 7 days produces 6mm diameter mycelia blocks, moves to each
In serial pastille culture medium, mycelia down, each handles 4 repetitions.It is disposed, is placed in 25 ± 1 DEG C of constant temperature biochemistry training
Support in case and cultivate.
Culture medium flat plate is taken out after 3 days, each processing colony diameter is measured with crossing method, the mycelia life of each processing is calculated
Long inhibiting rate.It is independent variable x according to the logarithm value of drug concentration (mg/L), using the probit value of corrected mortality as dependent variable y, point
Virulence regression equation is not set up, the EC50 and its mixture co-toxicity coefficient of single dose and each proportioning mixture are calculated using DPS softwares.Altogether
Malicious coefficient (CTC) >=120 shows as synergistic effect；Co-toxicity coefficient (CTC)≤80 shows as antagonism；80 ＜ co-toxicity coefficients
(CTC) ＜ 120 shows as summation action.Survey toxicity index (ATI)=(standard agent EC50/ reagent agent EC50) × 100.
Theoretical toxicity index (TTI)=(A percentage composition in A toxicity index × mixture)+(the hundred of B in B toxicity index × mixture
Divide content).Co-toxicity coefficient (CTC)=[mixture actual measurement toxicity index (ATI)/mixture theoretical toxicity index (TTI)] × 100.Knot
Fruit is as shown in table 1
Table 1：Compound of formula I and joint toxicity measuring result of the Formula II compound to canker of apple fruit
As can be seen from Table 1, the ratio of formula (I) and formula (II) be 5: 1,4: 1,3: 1,2: 1,1: 1,1: 2,1: 3,1: 4,1: 5 group
During conjunction, be respectively 118.93 to the CTC values of apple black skin shell bacterium, 125.37,127.03,124.74,130.09,137.90,
135.05th, 124.14,118.34, particularly when its ratio is between 1: 1-1: 3, synergistic function is particularly significant.
Embodiment 2
Contain the similitude in phenyl ring, structure due to formula (I) compound and formula (II) compound, in fact it could happen that while right
The bacterial strain of formula (I) and formula (II) resistance.We are used as antifungal agent using formula (I) and formula (II) in the compound of 1: 2 ratio.Compounding
In fungicide by weight containing 15% Formulas I, 30% Formula II, surplus be auxiliary material, by the fungicide of the compounding with 1
: used after 400 times of dilutions.
Medicament sensitivity test is carried out to the 41 pathogen strain fungies for being isolated from apple, the 41 pathogen strain fungi includes ascus
15 plants of bacterium, 12 plants of rest fungus, 9 plants of botrytis cinerea, mould 5 plants of column disk spore.As a result 400 times of dilutions pair of above-mentioned compounding fungicide are shown
38 pathogen strain fungi therein is effective, (2 plants of grey mold, 1 plant of column disk spore are mould invalid) invalid to 3 plants therein.
To above-mentioned three pathogen strains fungi, respectively with formula (I) compound and formula (II) compound test antibacterial situation, all do not have yet
It is effective, it follows that this three pathogen strains fungi has dual drug resistance or intersection to formula (I) compound and formula (II) compound
Drug resistance.
It is multiple in formula (I), formula (II) according to the stability of formula (I) and formula (II) compound, anti-fungal mechanism, action condition
On the basis of matching somebody with somebody, it is further combined jinggangmeisu, polyoxin, pesticide corrosion 120, kasugarnycin etc. and is screened.As a result show
The three of compounding acquisition are carried out containing the pesticide corrosion 120 in 15% Formulas I, the antifungal agent composition of 30% Formula II, adding 3-5%
First Fungicidal composition can produce inhibitory action to all 41 pathogen strain fungies for being isolated from apple.
The field test of embodiment three
The apple mildew state of an illness is investigated before medication, in state of an illness first time at initial stage dispenser, every dispenser in 10 days once, is altogether applied 2 times.
Investigate apple tree brown spot disease indexs and calculate preventive effect within 28 days after second of dispenser.Disease index and prevention effect calculation formula
It is as follows：
As a result show, it is described to be killed containing 15% compound of formula I, 30% Formula II compound, the compounding of 4% pesticide corrosion 120
Epiphyte pharmaceutical is up to more than 97% to the prevention effect of powdery mildew, and preventive effect phase is long.
In addition, ternary built fungicide of the present invention also has to rust of apple (Gymnosporangium yamadai), canker of apple fruit, apple marssonina leaf spot etc.
There is higher prevention effect, the prevention effect of 28 days is between 89-95% after second of dispenser.
Described above not limitation of the present invention, the present invention is also not limited to the example above.The art it is common
Technical staff is in the essential scope of the present invention, the variations, modifications, additions or substitutions made, and should also belong to the protection of the present invention
Scope, protection scope of the present invention is defined by claims.
Claims (10)
1. a kind of compound fungicide of Synergistic, it is characterised in that comprising with the Fungicidal active ingredient of following formula I and Formula II,
And, the active component for the plant pathogenic fungi that can suppress there is drug resistance for Formulas I and/or Formula II or it can suppress plant
Thing disease fungus produces the composition that drug resistance is produced for Formulas I and/or Formula II.
2. fungicide is combined as claimed in claim 1, the plant that can suppress that there is drug resistance for Formulas I and/or Formula II
The active component of disease fungus or plant pathogenic fungi can be suppressed produce the composition for producing drug resistance for Formulas I and/or Formula II be
Pesticide corrosion 120.
3. fungicide is combined as claimed in claim 1 or 2, it is characterised in that Formulas I: the weight ratio of Formula II is 4-1: 1-4.
4. fungicide is combined as claimed in claim 1 or 2, it is characterised in that described to suppress to have for Formulas I and/or Formula II
There is the active component of the plant pathogenic fungi of drug resistance or plant pathogenic fungi can be suppressed and produce for Formulas I and/or Formula II generation
The content of the composition of drug resistance is 3-6% (weight ratio).
5. fungicide is combined as claimed in claim 1 or 2, it is characterised in that the agricultural chemicals is aqua, pulvis, wettable powder
Agent, granula.
6. as described in claim 1 to 5 is any be combined fungicide, it is characterised in that by weight containing 15% Formulas I,
30% Formula II, 4% pesticide corrosion 120.
7. the application method of fungicide is combined as described in claim 1 to 6 is any, it is characterised in that described be combined is killed true
After microbial inoculum is diluted with 1: 200-800 times of weakly acidic pH or faintly acid solvent progress, the plant of pathogenic infection fungi is sprayed.
8. method as claimed in claim 7, it is characterised in that described disease fungus is superior pathogenic fungi, including ascus
Bacterium, basidiomycetes, Fungi Imperfecti etc.；Described plant includes apple, pears, peach, grape etc..
9. purposes of the fungicide in agricultural chemicals is prepared is combined as described in claim 1 to 6 is any.
10. purposes as claimed in claim 9, wherein the agricultural chemicals can be used for preventing and treating plant fungal disease, described plant
Fungi is superior pathogenic fungi, including sac fungus, basidiomycetes, Fungi Imperfecti etc.；Described plant includes apple, pears, peach, grape
Deng.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710440605.6A CN107047585A (en) | 2017-06-12 | 2017-06-12 | One kind is combined antifungal agricultural chemicals |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710440605.6A CN107047585A (en) | 2017-06-12 | 2017-06-12 | One kind is combined antifungal agricultural chemicals |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107047585A true CN107047585A (en) | 2017-08-18 |
Family
ID=59594539
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710440605.6A Pending CN107047585A (en) | 2017-06-12 | 2017-06-12 | One kind is combined antifungal agricultural chemicals |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107047585A (en) |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1273776A (en) * | 1999-01-27 | 2000-11-22 | 魏宏儒 | Chemical for preventing and treating vascular bundle diseases of plant |
| CN1288667A (en) * | 1999-09-21 | 2001-03-28 | 马越 | Diethofencarb-carbendazim composite germicide |
| CN101194618A (en) * | 2006-12-07 | 2008-06-11 | 上海杜邦农化有限公司 | Agricultural compositioncontaining cardendazim and diethofencarb, and use thereof |
| JP2011225497A (en) * | 2010-04-22 | 2011-11-10 | Sumitomo Chemical Co Ltd | Plant disease control method |
| CN102246783A (en) * | 2010-05-21 | 2011-11-23 | 王海林 | Diethofencarb and carbendazim wettable powder |
-
2017
- 2017-06-12 CN CN201710440605.6A patent/CN107047585A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1273776A (en) * | 1999-01-27 | 2000-11-22 | 魏宏儒 | Chemical for preventing and treating vascular bundle diseases of plant |
| CN1288667A (en) * | 1999-09-21 | 2001-03-28 | 马越 | Diethofencarb-carbendazim composite germicide |
| CN101194618A (en) * | 2006-12-07 | 2008-06-11 | 上海杜邦农化有限公司 | Agricultural compositioncontaining cardendazim and diethofencarb, and use thereof |
| JP2011225497A (en) * | 2010-04-22 | 2011-11-10 | Sumitomo Chemical Co Ltd | Plant disease control method |
| CN102246783A (en) * | 2010-05-21 | 2011-11-23 | 王海林 | Diethofencarb and carbendazim wettable powder |
Non-Patent Citations (1)
| Title |
|---|
| 沈宙等: "多菌灵与乙霉威复配对灰霉病的室内活性研究", 《现代农药》 * |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101028009A (en) | Caprotrahol and Bacillus subtilis compound agricultural chemicals | |
| CN101828564A (en) | Agricultural sterilizing composite containing thifluzamide | |
| Türkkan et al. | Evaluation of antifungal activity of sodium salts against onion basal rot caused by Fusarium oxysporum f. sp. cepae. | |
| Chen et al. | Activity of a novel bactericide, zinc thiazole against Xanthomonas oryzae pv. oryzae in Anhui Province of China | |
| CN101530099B (en) | Isothiazolone-containing bactericidal composition | |
| Talibi et al. | In vitro and in vivo antifungal activities of organic and inorganic salts against citrus sour rot agent Geotrichum candidum | |
| CN106973907A (en) | A kind of composition pesticide containing copper 8-hydroxyquinolinate and kasugarnycin and its application | |
| CN103222465A (en) | Sterilizing composition containing isopyrazam and triazole bactericide | |
| Kaewsalong et al. | Synergistic effects of combinations of novel strains of Trichoderma species and Coscinium fenestratum extract in controlling rice dirty panicle | |
| CN102771480B (en) | Bactericidal composition containing cuppric nonyl phenolsulfonate and triazole fungicide | |
| Sharma et al. | Evaluation of fungicides for the management of pearl millet [Pennisetum glaucum (L.)] blast caused by Magnaporthe grisea | |
| CN101946802B (en) | Bactericide composition with synergistic effect | |
| CN100393212C (en) | Sterilizing and insecticidal composition | |
| CN102308831B (en) | The bactericidal composition of a kind of pyraclostrobin-containing and dicarboxyl carboximide class | |
| CN113785838B (en) | Combination fungicides containing chlorophenoxyamide and procymidone | |
| CN107047585A (en) | One kind is combined antifungal agricultural chemicals | |
| CN107333792A (en) | By rosickyite azoles and the bactericide of the preventing and treating rice blast of miaow chaff azoles compounding | |
| CN102771488B (en) | Bactericidal composition containing isothiazolone | |
| CN107333791A (en) | By rosickyite azoles and the bactericide of the preventing and treating rice blast of OIT compounding | |
| CN107018984A (en) | A kind of bactericidal composition containing folpet and fluoxastrobin and application thereof | |
| CN105052955B (en) | A kind of disinfection and deinsectization composition and suspending agent thereof containing fluoxastrobin | |
| CN106106484A (en) | Synergistic bactericidal composition | |
| CN105941427B (en) | A kind of bactericidal composition and its application containing volution bacterium amine and zinc thiazole | |
| CN109303060A (en) | A kind of combination germicide and application containing benziothiazolinone and pyraoxystrobin | |
| CN108477199A (en) | A kind of bactericidal composition and application thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20170818 |
|
| RJ01 | Rejection of invention patent application after publication |