CN107019653A - A kind of anti-apolexis composition and preparation method thereof - Google Patents
A kind of anti-apolexis composition and preparation method thereof Download PDFInfo
- Publication number
- CN107019653A CN107019653A CN201710172679.6A CN201710172679A CN107019653A CN 107019653 A CN107019653 A CN 107019653A CN 201710172679 A CN201710172679 A CN 201710172679A CN 107019653 A CN107019653 A CN 107019653A
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- Prior art keywords
- skin
- vitamin
- calamine
- phases
- composition
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/678—Tocopherol, i.e. vitamin E
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/27—Zinc; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
Abstract
The invention discloses a kind of anti-apolexis composition and preparation method thereof, it is made up of the component of following percetage by weight：Vitamin A 0.7 1.1%, vitamin e1 7 23%, sucrose stearate 1.1 5.9%, calamine 11% 23%, surplus is glycine betaine.The composition of the present invention is on the basis of safety and environmental protection, by gently stimulating skin metabolism function, to promote skin function maintenance, protects skin, anti-aging.This composition emphasis is considered as carrier of the calamine as oiliness raw materials such as function raw material VA and VE, not only due to calamine has corresponding skin problem to have alleviation and healing effect, simultaneously as the surface porosity of its special pearl, can largely adsorption activity material, in addition the characteristics of it is easily scattered, equably can deliver to active matter required skin part in the case where abundance carries active matter, and active matter is sustained out step by step, so as to reach synergistic effect.
Description
Technical field
The present invention relates to cosmetic field, specifically, it is related to a kind of anti-apolexis composition and preparation method thereof.
Background technology
Skin anti-aging is one eternal problem of cosmetic field, and the scheme of research skin anti-aging is many at present.It is main
If using some plant components or active matter, according to a certain percentage after scope compounding, being used for a long time, and reach corresponding purpose
Demand.Plant component or related activity composition are relatively vulnerable to microorganism pollution because of raw material attribute, and place can typically use preservative
Form ensure product quality, but addition anti-corrosion there is security risk again.It is used for a long time simultaneously, consumer safety risk, ring
Protecting risk all can be very big.And of the invention, such issues that can efficiently solve, finding rational both effectiveness additive golden ratio
On the basis of compounding, the physical adsorption treatment to oil-phase component is employed, so that active ingredient can be sustained by reaching, moreover is used
Basic material can effectively reduce the characteristic of water activity to reduce the risk of microorganism pollution.And from the mesh reached without using preservative
, the security risks of product long-term use can be effectively reduced in this regard.In addition using natural in terms of raw material selection
It is degradable, the small raw material of effect on environment, so that while bringing U.S. for consumer, environmental protection.
The content of the invention
There is anti-aging it is an object of the invention to provide one kind, improve the environmentally friendly and safe of skin health state and resist
Anti-aging composition and preparation method thereof.
The present invention to achieve these goals, using following technical scheme：
A kind of anti-apolexis composition, is made up of the component of following percetage by weight：Vitamin A 0.7%-1.1%, dimension life
Plain E 17%-23%, sucrose stearate 1.1%-5.9%, calamine 11%-23%, surplus is glycine betaine.
The preparation method of above-mentioned anti-apolexis composition, comprises the following steps：
(1) stirred after vitamin A and vitamin E mixing, form A phases；
(2) after calamine pure water soaks, then it is ground with three-wheel roller machine, it is ensured that particle diameter is below 1 micron, then dries
It is dry standby, form B phases；
(3) A phases are equably sprayed in B phases, and are stirred, and form C phases；
(4) glycine betaine, sucrose stearate, C are mixed uniformly.
This addition of anti-apolexis composition total amount in cosmetics is 0.80%-0.90%.
Glycine betaine：It is because specific good performance of keeping humidity, indifferent equilibrium does not injure skin, while also possessing using it
Bactericidal antiphlogistic is acted on.Consider its moisture pick-up properties in this emphasis, water activity can be reduced well, it is to avoid microorganism pollution risk,
Therefore this raw material is used as base starting material.Simultaneously after final cosmetics are entered, performance of keeping humidity of the cosmetics to skin can be improved
With the general level of the health of improvement skin.
Vitamin A：Also known as retinol, using it, mainly considers its synthesis that may participate in glycoprotein, this for epithelium just
It is commonly formed, develops and maintains and is particularly significant.Pachylosis can be prevented, promotes skin normal growth and development.So as to reach regulation table
Skin and cuticula metabolism, anti-aging go the purpose of wrinkle.But VA addition can not be too high, otherwise it can run counter to desire.
Vitamin E：Also known as tocopherol, using it, it is good antioxidant mainly to consider it, is had into Skin Cell
Green Tea Extract chain reaction.Theoretically it is better than superoxide dismutase (SOD), in dermal application in prevention keratinization.While its
Deposition of the lipofuscin in cell can be eliminated, improves the normal function of cell, slows down histiocytic aging course.
Sucrose stearate：Using it, mainly consider its emulsifying agent for natural environmental protection, be particularly suitable for use in oil-in-water breast
Change system.0.01%-0.05% scope is, based on gradient experiment for several times, the emulsifying agent of this amount scope, effectively can to consolidate oil
Component parcel is scattered, while outward appearance is optimal.
Calamine：Main (ZnCO3) containing zinc carbonate, surface mealiness is matt, uneven, porous, like cellular.Body is light,
It is frangible.Odorless, taste micro-puckery.Major function：Detoxify removing nebula, the antipruritic sore of hygroscopic.For red eye, swell pain, blepharitis cililiaris, screen
The film triangular mass of mucous membrane growing from the inner corner of the eye, unhealing ulcer, pus is dripping, wet sore, pruitus.Its special cellular quality is mainly considered using it, can be with
The component of oiliness is adsorbed well, so as on skin after use, functional component progressively is sustained out.Together
When consider that it contains other abundant mineral elements, such as：Calcium, magnesium, iron, manganese, cobalt, copper etc., can suitably supplement the micro- of skin
Secondary element.Finally because of its metal and stone attribute, to pathogenic microorganisms, (the common staphylococcus aureus of wound has good suppression to make
With), there are alleviation and healing to act on to a variety of skin problems.
Compared with prior art, the present invention has the advantages that：The composition of the present invention is in safety and the base of environmental protection
On plinth, by gently stimulating skin metabolism function, to promote skin function maintenance, skin, anti-aging are protected.This composition weight
Point is considered as carrier of the calamine as oiliness raw materials such as function raw material VA and VE, not only due to calamine has corresponding skin to ask
Topic has alleviation and healing effect, simultaneously as the surface porosity of its special pearl, can largely adsorption activity material, plus
Its it is easily scattered the characteristics of, active matter can equably be delivered to required flesh in the case where abundance carries active matter
Skin part, and active matter is sustained out step by step, so as to reach synergistic effect.
Embodiment
The present invention will be described in further detail by embodiment.All compositions unless specified otherwise beyond, with percentage weight
Amount is represented.
Embodiment 1：A kind of anti-apolexis composition, is made up of the component of following percetage by weight：Vitamin A 0.7%, dimension
Raw element E 17%, sucrose stearate 1.1%, calamine 11%, surplus is glycine betaine.After vitamin A and vitamin E are mixed
Stir, form A phases；After calamine pure water soaks, then be ground with three-wheel roller machine, it is ensured that particle diameter 1 micron with
Under, then dry for standby, form B phases；A phases are equably sprayed in B phases, and are stirred, and form C phases；Glycine betaine, sucrose is hard
Resin acid ester, C, which are mixed, uniformly to be produced.
Embodiment 2：A kind of anti-apolexis composition, is made up of the component of following percetage by weight：Vitamin A 1.1%, dimension
Raw element E 23%, sucrose stearate 5.9%, calamine 23%, surplus is glycine betaine.After vitamin A and vitamin E are mixed
Stir, form A phases；After calamine pure water soaks, then be ground with three-wheel roller machine, it is ensured that particle diameter 1 micron with
Under, then dry for standby, form B phases；A phases are equably sprayed in B phases, and are stirred, and form C phases；Glycine betaine, sucrose is hard
Resin acid ester, C, which are mixed, uniformly to be produced.
Embodiment 3：A kind of anti-apolexis composition, is made up of the component of following percetage by weight：Vitamin A 1.0%, dimension
Raw element E 20%, sucrose stearate 3%, calamine 16%, surplus is glycine betaine.Stirred after vitamin A and vitamin E are mixed
Mix uniform, form A phases；After calamine pure water soaks, then be ground with three-wheel roller machine, it is ensured that particle diameter below 1 micron,
Dry for standby, forms B phases again；A phases are equably sprayed in B phases, and are stirred, and form C phases；Glycine betaine, sucrose is stearic
Acid esters, C, which are mixed, uniformly to be produced.
Embodiment 4：The Antisenility Experiment of embodiment 1
The gained anti-apolexis composition of embodiment 1 is weighed into good packaging by 0.08-0.09 grams, while attached 10 milliliters of sterilized waters,
Anti-apolexis composition is added in sterilized water when using, shakes up and can be used.
Method brief introduction：Using front and rear Self-controlled study.By apparatus measures VISA IMAQs and wrinkle areal analysis,
Effect of researcher's assessment, the anti-wrinkle that subject's self-evaluating comes after the crease-resistant class cosmetics use of comprehensive assessment or aging.
Number of subjects：At least 15 people.
Use time：At least 3 months, number of observation (totally 7 times)：0 week, 1 week, 2 weeks, 3 weeks, 4 weeks, 8 weeks and 12 weeks.
Test position：Face canthus portion.
Trial method：It is daily to use once, after clean face, after smearing, 3 minutes are massaged to skin absorption.Concrete condition
Such as table 1.
Table 1
Analytical conclusions：By showing that the anti-ageing composition is effectively reduced wrinkle of skin to 18 destination object tests.It is flat
It is using reduction by 13.38% in three months to reduce area.It can show that the obvious user of wrinkle improves notable simultaneously.Simultaneously to skin-color
Having in terms of plain deposition generally improves, bright color, more than user's overall assessment is good.Therefore judge this anti-ageing composition in above-mentioned ratio
It is effective under example, preparation technology, addition requirement.
Embodiment 2-3 is also according to the method for testing of embodiment 4, and its anti-aging effects is suitable with embodiment 1.
Claims (3)
1. a kind of anti-apolexis composition, it is characterised in that be made up of the component of following percetage by weight：Vitamin A 0.7%-
1.1%th, vitamin E 17%-23%, sucrose stearate 1.1%-5.9%, calamine 11%-23%, surplus is glycine betaine.
2. the preparation method of anti-apolexis composition described in claim 1, it is characterised in that comprise the following steps：
（1）Stirred after vitamin A and vitamin E mixing, form A phases；
（2）After calamine pure water soaks, then it is ground with three-wheel roller machine, it is ensured that particle diameter is below 1 micron, then dries standby
With formation B phases；
（3）A phases are equably sprayed in B phases, and are stirred, and form C phases；
（4）Glycine betaine, sucrose stearate, C are mixed uniformly.
3. a kind of cosmetics, it is characterised in that containing the anti-apolexis composition described in claim 1, it is 0.8%- that it, which adds weight,
0.9%。
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710172679.6A CN107019653A (en) | 2017-03-21 | 2017-03-21 | A kind of anti-apolexis composition and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710172679.6A CN107019653A (en) | 2017-03-21 | 2017-03-21 | A kind of anti-apolexis composition and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107019653A true CN107019653A (en) | 2017-08-08 |
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ID=59525741
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710172679.6A Pending CN107019653A (en) | 2017-03-21 | 2017-03-21 | A kind of anti-apolexis composition and preparation method thereof |
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| Country | Link |
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| CN (1) | CN107019653A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107982095A (en) * | 2017-10-19 | 2018-05-04 | 珀莱雅化妆品股份有限公司 | A kind of preparation method with crease-resistant slow-release solid microballoon |
| CN114306112A (en) * | 2021-12-28 | 2022-04-12 | 广州雅纯化妆品制造有限公司 | Anti-aging composition and preparation method thereof |
Citations (3)
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|---|---|---|---|---|
| CN101020860A (en) * | 2007-01-16 | 2007-08-22 | 刘思强 | Anti-senility golden shaddock oil |
| CN104856928A (en) * | 2015-06-03 | 2015-08-26 | 天津郁美净集团有限公司 | Anti-wrinkle and anti-aging cosmetic and preparation method thereof |
| CN105496835A (en) * | 2014-09-26 | 2016-04-20 | 杨丽莉 | Anti-aging face cream |
-
2017
- 2017-03-21 CN CN201710172679.6A patent/CN107019653A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101020860A (en) * | 2007-01-16 | 2007-08-22 | 刘思强 | Anti-senility golden shaddock oil |
| CN105496835A (en) * | 2014-09-26 | 2016-04-20 | 杨丽莉 | Anti-aging face cream |
| CN104856928A (en) * | 2015-06-03 | 2015-08-26 | 天津郁美净集团有限公司 | Anti-wrinkle and anti-aging cosmetic and preparation method thereof |
Non-Patent Citations (2)
| Title |
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| 侯连兵等: "《常用药物新剂型及临床应用》", 31 March 1997, 人民军医出版社 * |
| 徐鸿华等: "《中草药彩图手册.3》", 31 July 2003, 广东科技出版社 * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107982095A (en) * | 2017-10-19 | 2018-05-04 | 珀莱雅化妆品股份有限公司 | A kind of preparation method with crease-resistant slow-release solid microballoon |
| CN107982095B (en) * | 2017-10-19 | 2020-03-27 | 珀莱雅化妆品股份有限公司 | Preparation method of sustained-release solid microspheres with anti-wrinkle effect |
| CN114306112A (en) * | 2021-12-28 | 2022-04-12 | 广州雅纯化妆品制造有限公司 | Anti-aging composition and preparation method thereof |
| CN114306112B (en) * | 2021-12-28 | 2024-02-20 | 广州雅纯化妆品制造有限公司 | Anti-aging composition and preparation method thereof |
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| PB01 | Publication | ||
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| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20170808 |
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| RJ01 | Rejection of invention patent application after publication |