CN106976674A - Low temperature stores transferring device and its operation method - Google Patents
Low temperature stores transferring device and its operation method Download PDFInfo
- Publication number
- CN106976674A CN106976674A CN201710233171.2A CN201710233171A CN106976674A CN 106976674 A CN106976674 A CN 106976674A CN 201710233171 A CN201710233171 A CN 201710233171A CN 106976674 A CN106976674 A CN 106976674A
- Authority
- CN
- China
- Prior art keywords
- low temperature
- transferring device
- buffering area
- transmission mechanism
- door
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65G—TRANSPORT OR STORAGE DEVICES, e.g. CONVEYORS FOR LOADING OR TIPPING, SHOP CONVEYOR SYSTEMS OR PNEUMATIC TUBE CONVEYORS
- B65G1/00—Storing articles, individually or in orderly arrangement, in warehouses or magazines
- B65G1/02—Storage devices
- B65G1/04—Storage devices mechanical
Abstract
The invention discloses a kind of low temperature storage transferring device and its operation method, for transfer tank to be conveyed into freezer from external environment condition, low temperature storage transferring device includes：Seal assembly, the seal assembly includes inside door and external door, and the inside door is provided with interior elevating mechanism, the external door is provided with outer elevating mechanism, sealable buffering area is constituted between the inside door and external door, the inside door connects freezer, and the external door connects external environment condition；Transmission assembly, the transmission assembly includes outer transmission mechanism and interior transmission mechanism, and the outer transmission mechanism is used to the transfer tank being delivered to the buffering area from external environment condition, and the interior transmission mechanism is used to the transfer tank being conveyed into freezer from the buffering area.The low temperature storage transferring device of the present invention may insure transfer tank after uncapping, and biological specimen is not exposed to normal temperature environment, reduces sample damage.Buffering area can prevent frosting inside transfer tank, improve the success rate of automation access pipe.
Description
Technical field
The present invention relates to automated storing transferring device, more particularly to a kind of low temperature storage transferring device and its operation side
Method.
Background technology
The development of life science and the detection of clinical treatment field diseases analysis and the progress for the treatment of and health technology, promote
Enter demand more and more extensive to biological specimen, also the memory technology and equipment to biological specimen propose higher requirement,
Including security, the reliability and stability to storing sample, and the accuracy of sample access procedure and program, high efficiency and
Scientific requirement.The object of biological sample storage often covers large biological molecule, cell, tissue and organ equal samples, such as people
Body organ-tissue, whole blood, blood plasma, serum, biological fluid or through treated biological specimen (including DNA, RNA, albumen etc.).It is raw
The long term storage of thing sample, need to generally use alap temperature to reduce the biochemical reaction in sample, improve each in sample
Plant the stability of composition.The biological specimens such as large biological molecule, cell, tissue and organ, its conventional storage temperature often has -80 DEG C
(ultra low temperature freezer), -140 DEG C (liquid nitrogen gas phase or cryogenic refrigerators) and -196 DEG C (liquid nitrogen liquid phase) etc., moreover, temperature is lower,
The stable holding time of sample is longer.
Due to cooling in the program that ultralow temperature stores biological specimen, it is necessary to which line program can be entered to biological specimen.This mistake
Journey, by the temperature-fall period accurately controlled, into the freezing state of lower temperature, is namely by the biological specimen of normal temperature state
The most effective bioactivity for ensureing biological specimen, this low temperature generally requires to reach less than -60 DEG C, even lower.In order to realize
High-volume biological specimen it is long-term, stably, reliable memory and sampling, the low temperature or ultralow temperature biological specimen access arrangement of automation
Development and use the developing direction for being a certainty.Automation transferring device is to realize that automation low temperature or ultralow temperature are biological
One important step of sample access, it is the passage and section that biological specimen passes in and out biological specimen storage container from external environment condition
Point.
In the prior art, the biological specimen cryopreservation tube of completion program cooling will be inserted a relative small size temporarily
Portable low-temp transfer storage container in, and cover with insulation cover the gathering hole of this portable transfer storage container (as pushed up
Portion), then biological specimen institute is transported to by artificial or under normal temperature or non-ultra-low temperature surroundings automation transporter
On the outside of the ultralow temperature biological specimen storage container that need to enter, then each biological specimen is frozen by manual or automated device
Memory cell (such as biological specimen cryopreservation tube) inserts the freezing in container or space of biological specimen Cryopreservation equipment.However, existing
The ultralow temperature automatic biological sample storage device for having technology lacks a buffering with the low temperature environment of certain function of temperature control
Operating space or mechanism, are transferred to ultralow temperature storage from low temperature transfer storage container by biological specimen (sample cryopreservation tube) and set
Standby freezes in container or space, by taking European patent EP 2666694A1 as an example, track of the transfer storage tank in an open space
Upper transport, then when will enter freezer, by outside cap-opening mechanism, transfer cover is opened, then transfer tank enters back into cold
Storehouse；Although the program realizes automation transmission, but biological specimen for some time can be under open environment, easy knot
Frost, influences the bioactivity of biological specimen；In addition, the organization volume is larger, in-site installation is also more complicated with debugging process, unfavorable
In the large-scale promotion application of equipment.
The content of the invention
The technical problem to be solved in the present invention be in order to overcome transferring device of the prior art lack cushion space lack
Fall into and store transferring device and its operation method there is provided a kind of low temperature.
The present invention is to solve above-mentioned technical problem by following technical proposals：
A kind of low temperature stores transferring device, and for transfer tank to be conveyed into freezer from external environment condition, its feature is, described
Low temperature storage transferring device includes：
Seal assembly, the seal assembly includes inside door and external door, and the inside door is provided with interior elevating mechanism, the external door
Outer elevating mechanism is provided with, sealable buffering area is constituted between the inside door and external door, the inside door connects freezer, described outer
Door connection external environment condition；Under any circumstance, inside door and external door be all without opening simultaneously, it means that under any circumstance,
Buffering area is all without connection freezer and external environment condition simultaneously.Transfer tank so be may insure after uncapping, biological specimen will not be sudden and violent
It is exposed at normal temperature environment.
Transmission assembly, the transmission assembly includes outer transmission mechanism and interior transmission mechanism, and the outer transmission mechanism is used for will
The transfer tank is delivered to the buffering area from external environment condition, and the interior transmission mechanism is used for the transfer tank from the buffering
Area is conveyed into freezer.When inside door is closed and external door is closed, interior transmission mechanism and outer transmission mechanism are in initial position, this
When, outer transmission mechanism is fully located in buffering area.Interior transmission mechanism is always positioned at cool house internal.When inside door is closed and external door opening
When, buffering area is connected with external environment condition, and now transfer tank can be transported in buffering area by outer transmission mechanism from external environment condition.When
After transfer tank is completely into buffering area, inside door and external door can be simultaneously closed off, it is to be buffered to carrying out dehumidifying and cooling operation in buffering area
When temperature and humidity in area reaches setting value, operation of uncapping is carried out to transfer tank, opened while then keeping external door to close
Inside door, now buffering area and external environs, buffering area is connected with freezer, and transfer tank can be by interior transmission mechanism from buffering area
It is transported in freezer.
It is preferred that the inside door and the external door include outer layer and internal layer.Double-decker is conducive to the insulation of cushion.
It is preferred that the inside door elevating mechanism includes interior actuator, the external door elevating mechanism includes outer actuator.It is interior to drive
Moving part driving inside door lifting, outer actuator driving external door lifting, so as to control the opening and closing of inner-outer door.
It is preferred that the interior actuator and outer actuator be for by convert rotational motion be translational motion driving
Part.
It is preferred that the interior actuator and the outer actuator are rack-and-pinion.
It is preferred that the transmission assembly also includes transfer chair disk and automatic telescopic pallet, the transfer chair disk engaging
On the automatic telescopic pallet, the automatic telescopic pallet activity is matched with the outer transmission mechanism, the outer transmission mechanism
For the automatic telescopic pallet to be moved into the buffering area from external environment condition, the interior transmission mechanism is used for transfer chair
Disk is moved to freezer from the buffering area.Transfer chair disk can be locked on automatic telescopic pallet, and keeps stable, while in
Turning chair disk can also separate from automatic telescopic pallet.In transfer tank from during external environment condition is transported to buffering area, in
Turn chair disk to be placed on all the time on automatic telescopic pallet.Outer transmission mechanism can drive automatic telescopic pallet to cross inside door so that
A part for automatic telescopic pallet is located in freezer, and now automatic telescopic pallet and transfer chair disk unlock, interior conveyer
Structure can drive transfer chair disk to be separated from automatic telescopic pallet, and then outer transmission mechanism resets, and inside door is closed, interior conveyer
Structure continues to drive transfer chair disk to reach specified location, now can carry out accessing operation to sample in transfer tank.
It is preferred that the transfer chair tray bottom front and back end is provided with retaining wall, the interior transmission mechanism includes timing belt and gear
Block, the block is fixed on the timing belt, and the block can drive the transfer chair disk to move by the retaining wall.
One end of timing belt is stretched between the center of retaining wall and transfer chair disk, and the rotation of timing belt drives block against retaining wall, so that
Drive the movement of transfer chair disk.After the sample in transfer tank completes accessing operation, timing belt is rotated backward, so that block
Transfer chair disk and transfer tank thereon is promoted to return to automatic telescopic pallet.
It is preferred that the automatic telescopic pallet includes spacer pin, the transfer chair disk is provided with spacing hole, the spacer pin
It can automatically extend into and remove the spacing hole.The cooperation of spacer pin and spacing hole realizes transfer chair disk in automatic telescopic support
Locking on disk.When spacer pin stretches into spacing hole, transfer chair disk can not be moved relative to automatic telescopic pallet, so as to realize
Locking.When spacer pin removes spacing hole, transfer chair disk can be moved relative to automatic telescopic pallet, so as to realize unblock.
After unblock, transfer chair disk can be separated from automatic telescopic pallet.
It is preferred that the both sides of the automatic telescopic pallet are provided with pallet rack, the outer transmission mechanism includes gear and biography
Defeated rack, the transmission rack is fixed on outer transmission mechanism both sides, and the gear is engaged on the transmission rack and the pallet
Between rack.Keep engaging between gear and pallet rack, while also keeping engaging between gear and transmission rack.Pass through gear
Rotation, realize the flexible of pallet rack.
It is preferred that the transfer chair disk both sides are provided with some rollers, the interior transmission mechanism is described provided with two guide rails
Roller can be slided on the guide rail.
It is preferred that the low temperature storage transferring device also includes dehumidifying and cooling component, the dehumidifying and cooling component is used for will
Setting value is arrived in temperature and humidity regulation in the closed buffering area.
It is preferred that the low temperature storage transferring device also includes component of uncapping, the component of uncapping is including revolving part and carries
Part is risen, the component of uncapping is positioned at the buffering area.
It is preferred that the low temperature storage transferring device also includes operator control panel and environment display screen, the operator control panel is used for hand
The dynamic operation for operating the low temperature to store transferring device, the environment display screen is used to show interior freezer, buffering area, outside in real time
Humidity, temperature, the integral device working order of environmental area.
It is preferred that low temperature storage transferring device also includes shell, the cage connection fix the inside door, external door,
Outer transmission mechanism and interior transmission mechanism, realize modularization.
A kind of low temperature stores the operation method of transferring device, and its feature is, it utilizes above-mentioned low temperature storage transfer dress
Put, the operation method of the low temperature storage transferring device comprises the following steps：
S1, outside transmission, the inside door is closed using the interior elevating mechanism, opens described using the outer elevating mechanism
External door, the buffering area is delivered to using the outer transmission mechanism by the transfer tank from external environment condition；
S2, encapsulation process, close the external door using the outer elevating mechanism, seal the buffering area, buffering area is entered
The processing of row dehumidifying and cooling, then uncaps the transfer tank；
S3, internal transmission, the inside door is opened using the inside door elevating mechanism, using the interior transmission mechanism by transfer
Tank is conveyed into freezer from the buffering area, then resets the transmission assembly, closes the inside door.
It is preferred that the low temperature storage transferring device also includes transfer chair disk and automatic telescopic pallet, in step sl,
Transfer tank is placed on the transfer chair disk, and the transfer chair disk is placed on the automatic telescopic pallet, described automatic
Flexible pallet drives the transfer chair disk to be delivered to buffering area from external environment condition；In step s3, the transfer chair disk from
Separated on the automatic telescopic pallet, the transfer chair disk enters freezer by buffering area, and the automatic telescopic pallet stays in slow
Rush area.
It is preferred that in step s 2, inside and outside door termination carries out dehumidifying and preliminary cooling, when temperature and humidity reaches setting
After value, then uncapped.
On the basis of common sense in the field is met, above-mentioned each optimum condition can be combined, and produce each preferable reality of the present invention
Example.
The positive effect of the present invention is：The low temperature storage transferring device of the present invention may insure that transfer tank is being uncapped
Afterwards, biological specimen is not exposed to normal temperature environment, reduces sample damage；Buffering area can prevent frosting inside transfer tank, improve certainly
Dynamicization accesses the success rate of pipe；Using double-layer heat insulation door sealing mechanism, the integral heat insulation performance of freezer, reduction operation work(can be improved
Consumption, reduces the operating cost of biological sample bank, and when sample in transfer tank carries out accessing operation, inner-outer door can keep closing
Closed state, will not reduce the sealing of freezer.The low temperature storage transferring device of the present invention realizes modularization, all mechanisms and fixed
Position device is integrated into a module, and smaller by external action, installation and debugging are more convenient, it is easier to ensure that running precision.
Brief description of the drawings
Fig. 1 stores the dimensional structure diagram of transferring device for the low temperature of present pre-ferred embodiments.
Fig. 2 is the part-structure schematic diagram of the transmission assembly of present pre-ferred embodiments.
Fig. 3 is the side structure schematic view of the transfer chair disk of present pre-ferred embodiments.
Description of reference numerals：
Inside door 102
External door 104
Interior elevating mechanism 106
Outer elevating mechanism 108
Buffering area 110
Outer transmission mechanism 202
Interior transmission mechanism 204
Transfer chair disk 206
Automatic telescopic pallet 208
Transmission location sensor 210
Block 212
Retaining wall 214
Spacer pin 216
Spacing hole 218
Pallet rack 220
Gear 221
Transmit rack 222
Roller 224
Guide rail 226
Bootstrap block 228
Transfer chair disk displacement transducer 230
Dehumidifying and cooling interface 302
Uncap component 304
Uncap and monitor sensor 306
Operator control panel 308
Environment display screen 310
Shell 312
Embodiment
The present invention is further illustrated below by the mode of embodiment, but does not therefore limit the present invention to described reality
Apply among a scope.
The low temperature storage transferring device of the present embodiment as shown in Figure 1 to Figure 3, is mainly used in transfer tank is defeated from external environment condition
Send into freezer, storage has biological specimen in transfer tank, biological specimen herein include but is not limited to human organ tissue, whole blood,
DNA, RNA, albumen that blood plasma, serum, biological fluid, microorganism or warp are treated etc..The low temperature storage transfer dress of the present embodiment
Putting mainly includes seal assembly and transmission assembly.
As shown in figure 1, seal assembly includes inside door 102 and external door 104, inside door 102 and external door 104 are provided with sealing
Circle, it is ensured that sealing.Inside door 102 is provided with interior elevating mechanism 106, and external door 104 is provided with outer elevating mechanism 108, interior lift
Structure 106 and outer elevating mechanism 108 can control the up and down motion of inside door 102 and external door 104, so as to control inside door 102 and external door
104 on-off action.Sealable buffering area 110 is constituted between inside door 102 and external door 104, when inside door 102 and external door 104 are equal
When moving to extreme lower position, buffering area 110 is in closed state, and inside door 102 or external door 104 are moved upwards, and buffering area 110 is opened,
And and neighbouring regional connectivity, inside door 102 connection freezer, external door 104 connection external environment condition.When inside door 102 is closed and external door 104
During opening, buffering area 110 is connected with external environment condition, and is completely cut off with freezer；When inside door 102 is opened and external door 104 is closed, delay
Area 110 is rushed to connect with freezer, and and external environs；When inside door 102 close and external door 104 closing when, buffering area 110 with it is cold
Storehouse completely cuts off, while also completely cutting off with external environment condition.Under any circumstance, inside door 102 and external door 104 are all without opening simultaneously, and this is just
It is meant that under any circumstance, buffering area 110 is all without connection freezer and external environment condition simultaneously.It so may insure transfer tank
After uncapping, biological specimen is not exposed to normal temperature environment.
Transmission assembly include outer transmission mechanism 202 and interior transmission mechanism 204, outer transmission mechanism 202 be used for by transfer tank from
External environment condition is delivered to buffering area 110, and interior transmission mechanism 204 is used to transfer tank being conveyed into freezer from buffering area 110.Work as inside door
When 102 closings and the closing of external door 104, interior transmission mechanism 204 and outer transmission mechanism 202 are in initial position, now, outer transmission
Mechanism 202 is fully located in buffering area 110.Interior transmission mechanism 204 is always positioned at cool house internal.When inside door 102 is closed and external door
During 104 opening, buffering area 110 is connected with external environment condition, and now transfer tank can be conveyed by outer transmission mechanism 202 from external environment condition
Into buffering area 110.After transfer tank is completely into buffering area 110, inside door 102 and external door 104 can be simultaneously closed off, to buffering area
When temperature and humidity in 110 in progress dehumidifying and cooling operation, area 110 to be buffered reaches setting value, transfer tank is uncapped
Operation, opens inside door 102, now buffering area 110 and external environs, buffering area while then keeping external door 104 to close
110 connect with freezer, and transfer tank can be by interior transmission mechanism 204 from buffering area 110 is transported to freezer.
The transmission assembly of the present embodiment also includes transfer chair disk 206 and automatic telescopic pallet 208, and transmission assembly includes one
Individual level Four mechanism, the fourth stage is transfer chair disk 206, and the third level is automatic telescopic pallet 208, and the second level is outer transmission mechanism
202, the first order is interior transmission mechanism 204.Transfer chair disk 206 is fastened on automatic telescopic pallet 208, transfer chair disk 206
It can be locked on automatic telescopic pallet 208, and keep stable, while transfer chair disk 206 can also be from automatic telescopic pallet
Separated on 208.
The activity of automatic telescopic pallet 208 is matched with outer transmission mechanism 202, and outer transmission mechanism 202 is used for automatic telescopic support
Disk 208 is moved to buffering area 110 from external environment condition, and it is fully extended slow that automatic telescopic pallet 208 can carry transfer chair disk 206
Area 110 is rushed, that is, is fully located in external environment condition.There is depression at the middle part of transfer chair disk 206, transfer tank can be placed at this
In depression, and keep stable.After transfer tank is placed on transfer chair disk 206, automatic telescopic pallet 208 from external environment condition to
Buffering area 110 is retracted, until whole automatic telescopic pallets 208 is respectively positioned in buffering area 110, it is defeated from external environment condition in transfer tank
During being sent to buffering area 110, transfer chair disk 206 is placed on automatic telescopic pallet 208 all the time.Then external door 104 is closed
Close, while inside door 102 is also remained turned-off, can be to carrying out cool-down dehumidification operation in buffering area 110, and transfer tank is uncapped
Operation.
Interior transmission mechanism 204 is used to transfer chair disk 206 being moved to freezer, the outer energy of transmission mechanism 202 from buffering area 110
Enough automatic telescopic pallet 208 is driven to cross inside door 102 so that a part for automatic telescopic pallet 208 is located in freezer, now certainly
Dynamic flexible pallet 208 and transfer chair disk 206 unlock, and interior transmission mechanism 204 can drive transfer chair disk 206 from automatic
Separated on flexible pallet 208, then outer transmission mechanism 202 is resetted, and inside door 102 is closed, interior transmission mechanism 204 continues to drive transfer
Chair disk 206 reaches specified location, now can carry out accessing operation to sample in transfer tank.Sample in transfer tank is completed
After accessing operation, interior transmission mechanism 204 drives transfer chair disk 206 and transfer tank thereon to return to automatic telescopic pallet 208, so
Automatic telescopic pallet 208 and transfer chair disk 206 are locked afterwards, transmission assembly full recovery initial position.In outer transmission mechanism 202
On be provided with transmission location sensor 210, in real time monitor transmission assembly situation, with decide whether carry out next step
Action.
Inside door 102 and external door 104 include outer layer and internal layer.Outer layer is structural material, and internal layer is insulation material, such as poly-
One kind in urethane expanded material, vacuum insulation plate material, XPS extruded sheets material or polypropylene foam.Double-decker has
Beneficial to the insulation of cushion.The elevating mechanism of inside door 102 includes interior actuator, and the elevating mechanism of external door 104 includes outer actuator.It is interior to drive
Moving part driving inside door 102 is lifted, and outer actuator driving external door 104 is lifted, so as to control the opening and closing of inner-outer door.Interior actuator and outer
Actuator be for by convert rotational motion be translational motion actuator.In the present embodiment, interior actuator and outer driving
Part is rack-and-pinion, in other embodiments, and interior actuator and outer actuator can use timing belt, ball-screw and chain
Bar etc..
The bottom front and back end of transfer chair disk 206 is provided with retaining wall 214, and interior transmission mechanism 204 includes timing belt and block 212,
Block 212 is fixed on timing belt, and block 212 can be one or more, and be fixed on the outer peripheral face of timing belt, block
212 can drive transfer chair disk 206 to move by retaining wall 214.In the present embodiment, retaining wall 214 is the bottom of transfer chair disk 206
Side wall on the protruding block of portion front and back end, the two side walls both face towards the center of transfer chair disk 206, and one end of timing belt is stretched into
Between the center of retaining wall 214 and transfer chair disk 206, the rotation of timing belt drives block 212 against retaining wall 214, so as to drive
Transfer chair disk 206 is moved.In other embodiments, retaining wall 214 can also be before retaining wall 214 is the bottom of transfer chair disk 206
Side wall on the groove of rear end, equally, the two side walls both face towards the center of transfer chair disk 206.When transfer tank is from transfer tank
After being removed on pallet 206, timing belt is rotated backward, so that block 212 promotes transfer chair disk 206 to return to automatic telescopic pallet
208。
Automatic telescopic pallet 208 includes spacer pin 216, and transfer chair disk 206 is provided with spacing hole 218, and spacer pin 216 can
Automatically extend into and remove spacing hole 218.The cooperation of spacer pin 216 and spacing hole 218 realizes transfer chair disk 206 and stretched automatically
Locking on contracting pallet 208.When spacer pin 216 stretches into spacing hole 218, transfer chair disk 206 can not be relative to automatic telescopic
Pallet 208 is moved, so as to realize locking.When spacer pin 216 removes spacing hole 218, transfer chair disk 206 can be relative to certainly
Dynamic flexible pallet 208 is moved, so as to realize unblock.After unblock, transfer chair disk 206 can divide from automatic telescopic pallet 208
From.
As shown in Fig. 2 the both sides of automatic telescopic pallet 208 are provided with pallet rack 220, outer transmission mechanism 202 includes gear
221 are fixed on the outer both sides of transmission mechanism 202 with transmission rack 222, transmission rack 222, and gear 221 is engaged on transmission rack 222
Between pallet rack 220.Pallet rack 220 is two, respectively positioned at the both sides of automatic telescopic pallet 208.Transmit rack 222
Also it is two, respectively positioned at the both sides of outer transmission mechanism 202, the tooth of pallet rack 220 and transmission rack 222 is facing but do not connect
Touch.Gear 221 is two, respectively positioned at the both sides of outer transmission mechanism 202, and each gear 221 is respectively positioned on pallet rack 220
Transmission rack 222 between, between gear 221 and pallet rack 220 keep engage, while gear 221 with transmit rack 222 it
Between also keep engagement.By the rotation of gear 221, the flexible of pallet rack 220 is realized.
The both sides of transfer chair disk 206 are provided with some rollers 224, and interior transmission mechanism 204 is provided with two guide rails 226, roller 224
It can be slided on guide rail 226.As shown in figure 3, in the present embodiment, roller 224 1 has six, wherein three rollers 224
The side of transfer chair disk 206 is distributed in, the other three roller 224 is distributed in the opposite side of transfer chair disk 206.
The distance between guide rail 226 is consistent with the distance between the roller 224 of opposite side two, to ensure that roller 224 can on guide rail 226
To roll glibly.In order to increase stability of the roller 224 on guide rail 226, prevent transfer chair disk 206 from offseting, in guide rail
226 outside is also provided with four bootstrap blocks 228, and two of which bootstrap block 228 is distributed in the outside of a guide rail 226, in addition
Two bootstrap blocks 228 are distributed in the outside of another guide rail 226, equal and opposite side the mirror image of bootstrap block 228 of each bootstrap block 228
Symmetrically, each bootstrap block 228 is respectively provided with inclined-plane, the normal on the inclined-plane of the relative bootstrap block 228 of each two and plane-parallel,
And the intersection point of two normals falls between the midpoint of two relative bootstrap blocks 228 and the center of buffering area 110.Two guide rails
226 end is provided with a transfer chair disk displacement transducer 230, and it utilizes laser range finder, used in monitoring in real time
Turn the position of chair disk 206, realize the accurate control of transmission location.
In order that transfer tank carries out operation of uncapping under the environment of a safety, low temperature storage transferring device also includes dehumidifying
Cool component, and dehumidifying and cooling component is used to the temperature and humidity regulation in closed buffering area 110 arriving setting value.Dehumidifying and cooling
Component includes dehumidifying and cooling interface 302 and dehumidifying and cooling sensor, and dehumidifying and cooling interface 302 and dehumidifying and cooling sensor are electrically connected
Connect.After inside door 102 and external door 104 are simultaneously closed off, start to start dehumidifying and cooling sensor, if humidity in buffering area 110 and
Temperature is not reaching to setting value, then dehumidifying and cooling sensor sends to dehumidifying and cooling interface 302 and instructed, and opens dehumidifying and cooling interface
302, the humidity and temperature that are carried out in buffering area 110 in dehumidifying and cooling operation, area 110 to be buffered are reached using dehumidifying and cooling equipment
To setting value, then dehumidifying and cooling sensor sends to dehumidifying and cooling interface 302 and instructed, and closes dehumidifying and cooling interface 302.
Low temperature storage transferring device also includes component 304 of uncapping, and component 304 of uncapping includes revolving part and lifting member, uncapped
Component 304 is located at buffering area 110.The lid of transfer tank is unscrewed first with revolving part, then using lifting member by transfer tank
Lid move away tank mouth, after uncapping, lid is remained attached on transfer tank.Monitored by uncapping monitoring sensor 306
Uncap and whether complete, after monitoring sensor 306 of uncapping sends completion instruction, restart next step operation.Monitoring of uncapping is sensed
Device 306 uses photoelectric sensor.Low temperature storage transferring device also includes operator control panel 308 and environment display screen 310, is separately fixed at
The outside of external door 104, operator control panel 308 is used for the operation that manually operated low temperature stores transferring device, and environment display screen 310 is used for real
When show in freezer, buffering area 110, the humidity in external environment condition region, temperature, integral device working order.Low temperature stores transfer
Device also includes shell 312, and shell 312 is connected inside door 102, external door 104, outer transmission mechanism 202 and interior transmission mechanism
204, realize modularization.
The present embodiment also discloses the operation method that a kind of low temperature stores transferring device, and it is low using such as the present embodiment
Gentle storage transferring device, the described method comprises the following steps：
Outside transmission, inside door 102 is closed using interior elevating mechanism 106, and external door 104, profit are opened using outer elevating mechanism 108
Transfer tank is delivered to buffering area 110 from external environment condition with outer transmission mechanism 202；Encapsulation process, is closed using outer elevating mechanism 108
External door 104 is closed, buffering area 110 is sealed, dehumidifying and cooling processing is carried out to buffering area 110, then transfer tank uncapped；Inside is passed
It is defeated, inside door 102 is opened using the elevating mechanism of inside door 102, is conveyed into transfer tank from buffering area 110 using interior transmission mechanism 204
Freezer, then resets transmission assembly, closes inside door 102.In encapsulation process step, inside and outside door termination carries out dehumidifying and preliminary
Cooling, after temperature and humidity reaches setting value, then is uncapped.
Low temperature storage transferring device also includes transfer chair disk 206 and automatic telescopic pallet 208, in outside transmitting step
In, transfer tank is placed on transfer chair disk 206, and transfer chair disk 206 is placed on automatic telescopic pallet 208, automatic telescopic
Pallet 208 drives transfer chair disk 206 to be delivered to buffering area 110 from external environment condition；Internally in transmitting step, transfer chair disk
206 separate from automatic telescopic pallet 208, and transfer chair disk 206 enters freezer by buffering area 110, and automatic telescopic pallet 208 is stayed
In buffering area 110.
The low temperature storage transferring device of the present embodiment may insure transfer tank after uncapping, and biological specimen is not exposed to often
Warm environment, reduces sample damage；Buffering area can prevent frosting inside transfer tank, improve the success rate of automation access pipe；Using
Double-layer heat insulation door sealing mechanism, can improve the integral heat insulation performance of freezer, and reduction operation power consumption reduces the operation of biological sample bank
Cost, and when sample in transfer tank carries out accessing operation, inner-outer door may remain off state, will not reduce the close of freezer
Feng Xing.The low temperature storage transferring device of the present embodiment realizes modularization, and all mechanisms and positioner are integrated into a module,
Smaller by external action, installation and debugging are more convenient, it is easier to ensure that running precision.
Although the embodiment of the present invention is the foregoing described, it will be appreciated by those of skill in the art that this is only
For example, protection scope of the present invention is to be defined by the appended claims.Those skilled in the art without departing substantially from
On the premise of the principle and essence of the present invention, various changes or modifications can be made to these embodiments, but these changes and
Modification each falls within protection scope of the present invention.
Claims (17)
1. a kind of low temperature stores transferring device, for transfer tank to be conveyed into freezer from external environment condition, it is characterised in that described low
Gentle storage transferring device includes：
Seal assembly, the seal assembly includes inside door and external door, and the inside door is provided with interior elevating mechanism, and the external door is set
There is outer elevating mechanism, sealable buffering area is constituted between the inside door and external door, the inside door connects freezer, and the external door connects
Logical external environment condition；
Transmission assembly, the transmission assembly includes outer transmission mechanism and interior transmission mechanism, and the outer transmission mechanism is used for will be described
Transfer tank is delivered to the buffering area from external environment condition, and the interior transmission mechanism is used for the transfer tank is defeated from the buffering area
Send into freezer.
2. low temperature storage transferring device as claimed in claim 1, it is characterised in that the inside door and the external door include outer
Layer and internal layer.
3. low temperature as claimed in claim 1 stores transferring device, it is characterised in that the inside door elevating mechanism includes interior driving
Part, the external door elevating mechanism includes outer actuator.
4. low temperature as claimed in claim 3 stores transferring device, it is characterised in that the interior actuator and outer actuator are
For by convert rotational motion be translational motion actuator.
5. low temperature as claimed in claim 3 stores transferring device, it is characterised in that the interior actuator and the outer actuator
It is rack-and-pinion.
6. low temperature as claimed in claim 1 stores transferring device, it is characterised in that the transmission assembly also includes transfer chair
Disk and automatic telescopic pallet, the transfer chair disk are fastened on the automatic telescopic pallet, the automatic telescopic pallet activity
The outer transmission mechanism is matched with, the outer transmission mechanism is described for the automatic telescopic pallet to be moved to from external environment condition
Buffering area, the interior transmission mechanism is used to transfer chair disk being moved to freezer from the buffering area.
7. low temperature as claimed in claim 6 stores transferring device, it is characterised in that the transfer chair tray bottom front and back end is set
There is retaining wall, the interior transmission mechanism includes timing belt and block, and the block is fixed on the timing belt, and the block can
The transfer chair disk is driven to move by the retaining wall.
8. low temperature as claimed in claim 6 stores transferring device, it is characterised in that the automatic telescopic pallet includes spacing
Pin, the transfer chair disk is provided with spacing hole, and the spacer pin can automatically extend into and remove the spacing hole.
9. low temperature as claimed in claim 6 stores transferring device, it is characterised in that the both sides of the automatic telescopic pallet are provided with
Pallet rack, the outer transmission mechanism includes gear and transmission rack, and the transmission rack is fixed on outer transmission mechanism both sides, institute
Gear is stated to be engaged between the transmission rack and the pallet rack.
10. low temperature as claimed in claim 6 stores transferring device, it is characterised in that if the transfer chair disk both sides are provided with
Dry milling wheel, the interior transmission mechanism can be slided provided with two guide rails, the roller on the guide rail.
11. low temperature as claimed in claim 1 stores transferring device, it is characterised in that the low temperature storage transferring device is also wrapped
Dehumidifying and cooling component is included, the dehumidifying and cooling component is used for the temperature and humidity regulation in the closed buffering area to setting
Value.
12. low temperature as claimed in claim 1 stores transferring device, it is characterised in that the low temperature storage transferring device is also wrapped
Component of uncapping is included, the component of uncapping includes revolving part and lifting member, and the component of uncapping is positioned at the buffering area.
13. the low temperature storage transferring device as described in claim 1 to 12 any one, it is characterised in that the low temperature storage
Transferring device also includes operator control panel and environment display screen, and the operator control panel is used for the manually operated low temperature storage transferring device
Operation, the environment display screen is used in display freezer in real time, buffering area, the humidity in external environment condition region, temperature, integral device
Working order.
14. low temperature as claimed in claim 13 stores transferring device, it is characterised in that the low temperature storage transferring device is also wrapped
Shell is included, the cage connection fixes the inside door, external door, outer transmission mechanism and interior transmission mechanism, realizes modularization.
15. a kind of low temperature stores the operation method of transferring device, it is characterised in that it is any one using such as claim 1 to 14
Low temperature storage transferring device described in, the operation method of the low temperature storage transferring device comprises the following steps：
S1, outside transmission, the inside door is closed using the interior elevating mechanism, opens described outer using the outer elevating mechanism
Door, the buffering area is delivered to using the outer transmission mechanism by the transfer tank from external environment condition；
S2, encapsulation process, close the external door using the outer elevating mechanism, seal the buffering area, buffering area is removed
Wet cooling processing, then uncaps the transfer tank；
S3, internal transmission, the inside door is opened using the inside door elevating mechanism, using the interior transmission mechanism by transfer tank from
The buffering area is conveyed into freezer, then resets the transmission assembly, closes the inside door.
16. low temperature as claimed in claim 15 stores the operation method of transferring device, it is characterised in that in the low temperature storage
Rotary device also includes transfer chair disk and automatic telescopic pallet, and in step sl, transfer tank is placed on the transfer chair disk,
The transfer chair disk is placed on the automatic telescopic pallet, and the automatic telescopic pallet drives the transfer chair disk from outer
Portion's environment is delivered to buffering area；In step s3, the transfer chair disk is separated from the automatic telescopic pallet, the transfer
Chair disk enters freezer by buffering area, and the automatic telescopic pallet stays in buffering area.
17. low temperature as claimed in claim 15 stores the operation method of transferring device, it is characterised in that in step s 2, interior
External door is closed, and is carried out dehumidifying and preliminary cooling, after temperature and humidity reaches setting value, then is uncapped.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710233171.2A CN106976674B (en) | 2017-04-11 | 2017-04-11 | Low-temperature storage transfer device and operation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710233171.2A CN106976674B (en) | 2017-04-11 | 2017-04-11 | Low-temperature storage transfer device and operation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN106976674A true CN106976674A (en) | 2017-07-25 |
| CN106976674B CN106976674B (en) | 2022-11-04 |
Family
ID=59344294
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710233171.2A Active CN106976674B (en) | 2017-04-11 | 2017-04-11 | Low-temperature storage transfer device and operation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106976674B (en) |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107624751A (en) * | 2017-09-15 | 2018-01-26 | 上海原能细胞生物低温设备有限公司 | Cryogenic storage system |
| CN108792391A (en) * | 2018-07-06 | 2018-11-13 | 中国科学院自动化研究所（洛阳）机器人与智能装备创新研究院 | A kind of automatic picking mechanism |
| CN109230138A (en) * | 2018-10-09 | 2019-01-18 | 上海原能细胞生物低温设备有限公司 | A kind of biological sample cooling storage integrated device and its operating method |
| CN109368107A (en) * | 2018-11-09 | 2019-02-22 | 上海原能细胞生物低温设备有限公司 | A kind of biological sample repository and its storage method |
| CN112093361A (en) * | 2019-06-18 | 2020-12-18 | 克利夫伦公司 | Automatic parcel terminal equipment |
| CN112551076A (en) * | 2020-12-14 | 2021-03-26 | 上海新科乾物联技术有限公司 | Track transfer system |
| CN112841172A (en) * | 2021-01-25 | 2021-05-28 | 苏州贝康医疗器械有限公司 | Sample transfer device and method for controlling sample transfer device |
| WO2023045048A1 (en) * | 2021-09-22 | 2023-03-30 | 基点生物科技(成都)有限公司 | Refrigerator for storing biological sample |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN202609559U (en) * | 2012-05-30 | 2012-12-19 | 深圳市腾达工业自动设备有限公司 | Vacuum junction box |
| CN102842528A (en) * | 2012-09-04 | 2012-12-26 | 青岛赛瑞达电子装备股份有限公司 | Method for transferring workpieces to enter and exit vacuum environment and ensuring workpieces to pass through processing region in vacuum environment and equipment |
| EP2614320A2 (en) * | 2010-09-09 | 2013-07-17 | Hamilton Storage Technologies, Inc. | Tube picking mechanisms with an ultra-low temperature or cryogenic picking compartment |
| CN106185343A (en) * | 2016-08-30 | 2016-12-07 | 台州市通益机械设备有限公司 | A kind of slack tank stacking machine automatically |
| CN206050781U (en) * | 2016-07-28 | 2017-03-29 | 李荣根 | Conveying mechanism and baking box delivered inside device |
| CN206735138U (en) * | 2017-04-11 | 2017-12-12 | 上海原能细胞医学技术有限公司 | Low temperature stores transferring device |
-
2017
- 2017-04-11 CN CN201710233171.2A patent/CN106976674B/en active Active
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2614320A2 (en) * | 2010-09-09 | 2013-07-17 | Hamilton Storage Technologies, Inc. | Tube picking mechanisms with an ultra-low temperature or cryogenic picking compartment |
| CN202609559U (en) * | 2012-05-30 | 2012-12-19 | 深圳市腾达工业自动设备有限公司 | Vacuum junction box |
| CN102842528A (en) * | 2012-09-04 | 2012-12-26 | 青岛赛瑞达电子装备股份有限公司 | Method for transferring workpieces to enter and exit vacuum environment and ensuring workpieces to pass through processing region in vacuum environment and equipment |
| CN206050781U (en) * | 2016-07-28 | 2017-03-29 | 李荣根 | Conveying mechanism and baking box delivered inside device |
| CN106185343A (en) * | 2016-08-30 | 2016-12-07 | 台州市通益机械设备有限公司 | A kind of slack tank stacking machine automatically |
| CN206735138U (en) * | 2017-04-11 | 2017-12-12 | 上海原能细胞医学技术有限公司 | Low temperature stores transferring device |
Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107624751A (en) * | 2017-09-15 | 2018-01-26 | 上海原能细胞生物低温设备有限公司 | Cryogenic storage system |
| CN108792391A (en) * | 2018-07-06 | 2018-11-13 | 中国科学院自动化研究所（洛阳）机器人与智能装备创新研究院 | A kind of automatic picking mechanism |
| CN109230138A (en) * | 2018-10-09 | 2019-01-18 | 上海原能细胞生物低温设备有限公司 | A kind of biological sample cooling storage integrated device and its operating method |
| CN109230138B (en) * | 2018-10-09 | 2023-05-26 | 上海原能细胞生物低温设备有限公司 | Biological sample cooling and storing integrated device and operation method thereof |
| CN109368107A (en) * | 2018-11-09 | 2019-02-22 | 上海原能细胞生物低温设备有限公司 | A kind of biological sample repository and its storage method |
| CN112093361A (en) * | 2019-06-18 | 2020-12-18 | 克利夫伦公司 | Automatic parcel terminal equipment |
| US11625969B2 (en) | 2019-06-18 | 2023-04-11 | Cleveron As | Automated parcel terminal |
| US11922755B2 (en) | 2019-06-18 | 2024-03-05 | Cleveron As | Automated parcel terminal |
| CN112551076A (en) * | 2020-12-14 | 2021-03-26 | 上海新科乾物联技术有限公司 | Track transfer system |
| CN112841172A (en) * | 2021-01-25 | 2021-05-28 | 苏州贝康医疗器械有限公司 | Sample transfer device and method for controlling sample transfer device |
| WO2023045048A1 (en) * | 2021-09-22 | 2023-03-30 | 基点生物科技(成都)有限公司 | Refrigerator for storing biological sample |
Also Published As
| Publication number | Publication date |
|---|---|
| CN106976674B (en) | 2022-11-04 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN106976674A (en) | Low temperature stores transferring device and its operation method | |
| CN206735138U (en) | Low temperature stores transferring device | |
| CN206734993U (en) | Low temperature stores buffer sealing device | |
| CN107624751A (en) | Cryogenic storage system | |
| WO2021068373A1 (en) | Automatic biological sample library | |
| CN105857937B (en) | Cryopreservation tube access device and liquid nitrogen container access system | |
| EP2237048B1 (en) | Storage apparatus for storing products | |
| CN105379706B (en) | The automatic access control device of frozen cell | |
| EP2063274A2 (en) | Storage-access apparatus for storing products and storage system thereof | |
| CN109292448A (en) | Biological sample intellectual access mechanism | |
| CN109368107A (en) | A kind of biological sample repository and its storage method | |
| CN209291249U (en) | A kind of biological sample transhipment stocking mechanism | |
| CN208882638U (en) | A kind of storage system | |
| CN207726012U (en) | A kind of rotating disc type low temperature access integrated device | |
| CN207269729U (en) | Cryogenic storage system | |
| CN110511872A (en) | Cell batch automatic production equipment and its working method | |
| CN210213516U (en) | Liquid nitrogen storage device | |
| CN210213517U (en) | Liquid nitrogen storage device with automatic access function | |
| CN108726069A (en) | A kind of low-temperature storage device and storage system | |
| CN206735240U (en) | Low temperature stores transmitting device | |
| CN109399043B (en) | Biological sample transferring and storing mechanism | |
| CN208470954U (en) | Cryopreservation tube device for sorting | |
| CN218967860U (en) | Butt joint buffer mechanism for biological sample low-temperature storage mechanism | |
| CN111907943A (en) | Liquid nitrogen storage device with automatic access function | |
| CN210486207U (en) | Biological cell preservation refrigerator with high refrigeration efficiency |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| TA01 | Transfer of patent application right | ||
| TA01 | Transfer of patent application right |
Effective date of registration: 20200110 Address after: 200120 Room 102, floor 1, building 4, no.1227, zhangheng road and no.1118, Halley Road, China (Shanghai) pilot Free Trade Zone, Pudong New Area, Shanghai Applicant after: SHANGHAI ORIGINCELL BIOLOGICAL CRYO EQUIPMENT Co.,Ltd. Address before: 201203 Shanghai Free Trade Zone in Pudong New Area Cailun Road, room 816 No. 780 Applicant before: SHANGHAI ORIGINCELL MEDICAL TECHNOLOGY Co.,Ltd. |
|
| GR01 | Patent grant | ||
| GR01 | Patent grant |