CN109399043B - Biological sample transferring and storing mechanism - Google Patents
Biological sample transferring and storing mechanism Download PDFInfo
- Publication number
- CN109399043B CN109399043B CN201811424516.3A CN201811424516A CN109399043B CN 109399043 B CN109399043 B CN 109399043B CN 201811424516 A CN201811424516 A CN 201811424516A CN 109399043 B CN109399043 B CN 109399043B
- Authority
- CN
- China
- Prior art keywords
- driving
- axial
- storage
- tube taking
- plate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 239000012472 biological sample Substances 0.000 title claims abstract description 48
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims abstract description 168
- 229910052757 nitrogen Inorganic materials 0.000 claims abstract description 84
- 238000007710 freezing Methods 0.000 claims abstract description 43
- 230000008014 freezing Effects 0.000 claims abstract description 43
- 210000001503 joint Anatomy 0.000 claims abstract description 41
- 230000005540 biological transmission Effects 0.000 claims description 46
- 238000005187 foaming Methods 0.000 claims description 31
- 239000007788 liquid Substances 0.000 claims description 23
- 238000001035 drying Methods 0.000 claims description 15
- 230000000007 visual effect Effects 0.000 claims description 6
- 238000004321 preservation Methods 0.000 claims description 5
- 239000000284 extract Substances 0.000 claims description 4
- 230000006698 induction Effects 0.000 claims description 4
- 238000000034 method Methods 0.000 abstract description 12
- 230000000694 effects Effects 0.000 abstract description 2
- 238000000926 separation method Methods 0.000 abstract description 2
- 238000009413 insulation Methods 0.000 description 8
- 238000003032 molecular docking Methods 0.000 description 7
- 239000006260 foam Substances 0.000 description 5
- 238000010586 diagram Methods 0.000 description 4
- 230000033001 locomotion Effects 0.000 description 4
- 238000007598 dipping method Methods 0.000 description 3
- 238000000605 extraction Methods 0.000 description 3
- 238000007789 sealing Methods 0.000 description 3
- 238000005138 cryopreservation Methods 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000004071 biological effect Effects 0.000 description 1
- 229920002521 macromolecule Polymers 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 238000010408 sweeping Methods 0.000 description 1
- 238000010257 thawing Methods 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65G—TRANSPORT OR STORAGE DEVICES, e.g. CONVEYORS FOR LOADING OR TIPPING, SHOP CONVEYOR SYSTEMS OR PNEUMATIC TUBE CONVEYORS
- B65G1/00—Storing articles, individually or in orderly arrangement, in warehouses or magazines
- B65G1/02—Storage devices
- B65G1/04—Storage devices mechanical
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/02—Preservation of living parts
- A01N1/0236—Mechanical aspects
- A01N1/0263—Non-refrigerated containers specially adapted for transporting or storing living parts whilst preserving, e.g. cool boxes, blood bags or "straws" for cryopreservation
- A01N1/0268—Carriers for immersion in cryogenic fluid, both for slow-freezing and vitrification, e.g. open or closed "straws" for embryos, oocytes or semen
Landscapes
- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- Dentistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Warehouses Or Storage Devices (AREA)
Abstract
The invention discloses a biological sample transferring and storing mechanism, which comprises a transferring box, a deep low-temperature storage tank and a nitrogen supply device, wherein the transferring box can be connected onto the deep low-temperature storage tank in an abutting mode or separated from the deep low-temperature storage tank in a relatively-deep mode, and the transferring box can transfer a received frozen storage pipe into the abutting-joint deep low-temperature storage tank; the nitrogen supply device can respectively supply nitrogen to the transfer box and the deep low-temperature storage tank; the transfer box and the deep low-temperature storage tank are arranged and can be in butt joint or separation; the freezing tube with biological samples is placed into a transfer box through a transfer tank, and then the transfer box is moved to a deep low-temperature storage tank and is in butt joint with the deep low-temperature storage tank; the two are integrated after being in butt joint, and the transfer box is operated again to transfer the frozen storage tube into the deep low-temperature storage tank for storage; in the whole process, the biological sample is in a deep low-temperature storage environment in the whole process, so that the activity of the biological sample is greatly ensured.
Description
Technical Field
The invention relates to the field of biological sample storage equipment, in particular to a biological sample transferring and storing mechanism.
Background
Biological sample libraries are devices that standardize the collection, processing, storage of samples of biological macromolecules, cells, tissues, and organs of healthy and diseased organisms. Before storing, the biological sample needs to be dormant by program cooling and then is stored in a liquid nitrogen container or a cryogenic refrigerator. For certain specific biological samples, the storage process needs to ensure the protection of an all-cold chain, and the whole process needs to be in a deep low-temperature environment to protect the biological activity and avoid repeated freeze thawing damage. In the prior art, biological samples are stored, wherein one condition is that the biological samples to be stored are manually placed into a deep low-temperature storage tank, and the other condition is that the biological samples are stored in a transfer mechanism, the transfer mechanism is conveyed to the side of the deep low-temperature storage tank, and then the biological samples are taken out from the transfer mechanism and placed into the deep low-temperature storage tank; the first condition causes the biological sample to be exposed to non-low temperature environment for a long time in the manual transportation process, and generates larger damage risk to the biological sample; the second case also presents a time period during which the biological sample is exposed to non-cryogenic environments, with risks to the storage of the biological sample. In the technical scheme of patent number 2017112686472 disclosed in the prior art, the transfer device is in butt joint with the target place by using the manipulator, so that the labor is randomly saved, but the manipulator also needs to take out the biological sample from the transfer device and then put the biological sample into the target place, and the biological sample is damaged.
Disclosure of Invention
The invention aims to solve the problems that in the prior art, when a biological sample is stored, the biological sample cannot be guaranteed to be in a cold chain environment in the whole course, and a large safety risk is brought to the stored biological sample.
The invention solves the technical problems by adopting the following technical scheme: a biological sample transfer storage mechanism, comprising a transfer box, a cryogenic storage tank and a nitrogen supply device, wherein the transfer box can be connected to the cryogenic storage tank in an abutting mode or separated from the cryogenic storage tank in a relatively deep mode, and the transfer box can transfer a received frozen storage pipe into the abutting-connected cryogenic storage tank; the nitrogen supply device can supply nitrogen to the transfer box and the cryogenic storage tank respectively.
Preferably, the transfer box comprises a transfer box shell, a receiving door, a butt joint door, an operation box, a pipe taking component and a transfer shoveling component; the transfer box shell is provided with a receiving door and a butt joint door, and the butt joint door is arranged on the end surface of the transfer box, which is in butt joint with the deep low-temperature storage tank; the operation box, the pipe taking component and the transferring shovel delivering component are all arranged in the transferring box shell, a freezing pipe or a transferring tank with biological samples can enter the operation box through a receiving door, the transferring shovel delivering component can penetrate through a freezing pipe storage disc in the docking door shovel delivering deep low-temperature storage tank, and the pipe taking component can extract the freezing pipe in the operation box into the freezing pipe storage disc on the transferring shovel delivering component.
Preferably, the transfer box further comprises a transfer tank temporary storage frame, a storage plate, a visual window and an operation inlet; an operation inlet is formed in the transfer box shell, and a visual window is formed in the transfer box shell above the operation inlet; the transfer tank temporary storage rack is arranged in the transfer tank shell and corresponds to the receiving door, the storage plate is arranged in the operation box, and the storage plate can store the freezing storage pipe storage tray.
Preferably, the transferring and shoveling component comprises a lifting pushing component, an axial pushing component and a tray;
The lifting pushing assembly comprises a lifting driving motor and a lifting screw rod, and the lifting driving motor drives the lifting screw rod to rotate; the axial pushing assembly comprises an axial driving piece, an axial supporting plate, an axial bearing seat, an axial transmission bottom rail, an axial sliding piece and an axial transmission piece; a screw nut is arranged at the upper end of the axial supporting plate and is in threaded connection with the lifting screw; the lower end of the axial supporting plate is fixed with the axial bearing seat, the axial transmission bottom rail is arranged on the axial bearing seat, the axial driving piece drives the axial transmission piece, and the axial sliding piece moves on the axial transmission bottom rail under the drive of the axial transmission piece; the tray is disposed on the axial slider.
Preferably, the axial transmission part comprises a first driving wheel, a second driving wheel, a first driven wheel, a second driven wheel, a first driving chain and a second driving chain; the axial driving piece comprises an axial driving motor, an axial driving wheel and a driving chain;
The axial transmission bottom rail is a concave rail, a motor shaft of the axial driving motor is coaxially connected with the axial driving wheel, and the axial driving wheel is connected with the first driving wheel through a driving chain; a drive connecting shaft is coaxially arranged between the first drive wheel and the second drive wheel, the drive connecting shaft is rotatably arranged on the axial transmission bottom rail, and the first drive wheel and the second drive wheel are symmetrically arranged on two sides of the front end of the axial transmission bottom rail; the first driving wheel is in transmission connection with the first driven wheel through a first driving chain, and the second driving wheel is in transmission connection with the second driven wheel through a second driving chain; the first driving chain is fixedly provided with a first driving plate, and the second driving chain is fixedly provided with a second driving plate;
The axial sliding part comprises an axial sliding plate and an axial sliding wheel, the axial sliding plate is slidably arranged on the upper end face of the axial transmission bottom rail, the axial sliding wheel is rotatably arranged on the lower end face of the axial sliding plate, and the axial sliding wheel is positioned in a groove of the axial transmission bottom rail to slide; the first driving plate and the second driving plate respectively act on the axial sliding plate; the tray is arranged at one end of the axial sliding plate far away from the axial driving piece.
Preferably, the tube taking component comprises a tube taking fixing frame, a tube taking driving sliding table, a tube taking sliding plate, a tube taking induction plate, a tube taking first sensor, a tube taking second sensor, a sliding driving motor and a tube taking assembly;
The tube taking fixing frame is fixed in the transfer box shell, the tube taking driving sliding table is arranged on the tube taking fixing frame, the tube taking sliding plate is slidably arranged on the tube taking driving sliding table, and the sliding driving motor drives the tube taking sliding plate to slide; the tube taking induction plate is arranged on the tube taking sliding plate, and the tube taking first sensor and the tube taking second sensor are respectively arranged at two side ends of the tube taking driving sliding table; the tube taking assembly is fixed with the tube taking sliding plate;
the tube taking assembly comprises a tube taking driving assembly, a tube taking rotating shaft, a tube taking receiving plate and a tube taking piece, wherein the tube taking driving assembly is fixed with the tube taking sliding plate, the tube taking rotating shaft is arranged on the tube taking driving assembly, and the tube taking driving assembly drives the tube taking rotating shaft to rotate in the axial direction and the circumferential direction;
one end of the tube taking receiving plate is connected with the tube taking rotating shaft, the other end of the tube taking receiving plate is connected with the tube taking piece, and the tube taking piece can absorb the freezing tube.
Preferably, a nitrogen outlet is formed in the upper end face of the transfer box, and an air outlet valve is arranged on the nitrogen outlet; the nitrogen supplying device supplies nitrogen to the operation box.
Preferably, the cryogenic storage tank comprises a rotary automatic door; the deep low-temperature storage tank is provided with an access hole, the rotary automatic door acts on the access hole, and the rotary automatic door corresponds to the butt joint door;
The rotary automatic door comprises a speed reducing motor, a rotary door transmission assembly, a door body, a foaming baffle plate, a heat-preserving door plate, a foaming heat-preserving cover and a foaming fixing plate frame; the heat-insulating door plate is arranged on the door body, the foaming fixing plate frame is arranged on the periphery of the access hole, the foaming heat-insulating cover is arranged on the foaming fixing plate frame and covers the access hole, and the foaming baffle is arranged on the foaming heat-insulating cover; a door hole is formed through the foaming baffle plate and the foaming heat preservation cover, and the door body is covered on the door hole;
The speed reducing motor can drive the door body to open or close through driving the rotary door transmission assembly.
Preferably, the system further comprises a control system; the control system can control the transfer box, the deep low-temperature storage tank and the nitrogen supply device;
A display is arranged on the cryogenic storage tank, a code scanning component is arranged in the transfer box, and the display and the code scanning component are electrically connected with the control system; the code scanning component can scan codes of the freezing storage pipes transferred into the deep low-temperature storage tank and display the codes on the display.
Preferably, a liquid nitrogen filling valve is arranged on the deep low-temperature storage tank, and a liquid nitrogen butt joint hole is arranged on the transfer box shell;
The liquid nitrogen filling valve outwards extends and is provided with a first drying pipe, the first drying pipe accessible liquid nitrogen butt joint hole with the operation box intercommunication, the liquid nitrogen filling valve outwards extends and is equipped with the second drying pipe, the second drying pipe with inside intercommunication of dark low temperature holding vessel.
Preferably, the cryogenic storage tank further comprises a storage rack, a storage first driving motor, a storage second driving motor, a driving disc, a shifting fork piece and a storage driving screw rod;
the middle part of the storage rack is provided with a storage driving groove downwards, the lower end of the shifting fork piece is fixed in the storage driving groove, the upper end of the shifting fork piece is fixedly provided with a driving disc, a motor shaft of the storage driving first motor is outwards extended to be provided with an A driving wheel, and the A driving wheel is in meshed connection with the driving disc;
The motor shaft of the storage second driving motor extends outwards to be provided with a storage driving screw rod, the storage driving screw rod penetrates through the driving disc and the shifting fork piece to extend into the storage driving groove, a driving nut is upwards arranged on the bottom wall of the storage driving groove, and the storage driving screw rod is in threaded connection with the driving nut.
Preferably, the lower end of the cryogenic storage tank is provided with a moving wheel, and the end face of the cryogenic storage tank, which is far away from the transfer box, is provided with a pushing handle.
The invention has the following beneficial effects: the transfer box and the deep low-temperature storage tank are arranged and can be in butt joint or separation; the freezing tube with biological samples is placed into a transfer box through a transfer tank, and then the transfer box is moved to a deep low-temperature storage tank and is in butt joint with the deep low-temperature storage tank; the two are integrated after being in butt joint, and the transfer box is operated again to transfer the frozen storage tube into the deep low-temperature storage tank for storage; in the whole process, the biological sample is in a deep low-temperature storage environment in the whole process, so that the activity of the biological sample is greatly ensured.
Drawings
FIG. 1 is a schematic diagram of a biological sample transport and storage mechanism;
FIG. 2 is a cross-sectional view of a biological sample transport storage mechanism;
FIG. 3 is a schematic diagram showing a structure of a transfer box and a cryogenic storage tank in a separated state;
FIG. 4 is an exploded view of a transfer box structure;
FIG. 5 is a schematic view of the internal structure of the transfer box;
FIG. 6 is a schematic view of a tube taking member;
FIG. 7 is a side view of an axial drive bottom rail;
FIG. 8 is a schematic diagram of the internal structure of a cryogenic storage tank;
FIG. 9 is an exploded view of a cryogenic storage tank;
fig. 10 is an exploded view of the storage rack structure.
The labels in the figures are: 1-a transfer box; 101-a transfer box housing; 102-a receiving gate; 103-butt-joint door; 104-an operation box; 105-taking a tube member; 106-a transfer shovel member; 107-a cryopreservation tube tray; 108, temporary storage frames of transfer tanks; 109-storage plate; 110-visual window; 111-an operation inlet; 112-a first access port; 113-a second access port; 114-a nitrogen outlet; 115-an air outlet valve; 116-code sweeping component;
161-lifting push assembly; 162-axial push assembly; 163-tray; 164-lifting driving motor; 165-lifting screw rod; 166-axial drive; 167-an axial support plate; 168-an axial socket; 169-axial drive bottom rail; 170-an axial slide; 171-an axial transmission; 172-a lead screw nut; 173-a first drive wheel; 174-a second driving wheel; 175-a first driven wheel; 176-a second driven wheel; 177-a first drive chain; 178-a second drive chain; 179-an axial drive motor; 180-axially driving the driving wheel; 181-driving a chain; 183-first drive plate; 184-a second drive plate; 185-an axial sliding plate;
1051-tube-taking fixing frame; 1052-tube-taking drive slide table; 1053-tube-taking slide plate; 1054-tube removal sensing plate; 1055-a first sensor; 1056-a second sensor; 1057-slide drive motor; 1059-a tube extraction drive assembly; 1060-taking a tube rotation shaft; 1061-a tube-taking receiving plate; 1062-taking out a pipe fitting;
2-a deep cryogenic storage tank; 201-a storage area; 202-rotating an automatic door; 203-access holes; 204-a gear motor; 205-a revolving door drive assembly; 206-door body; 207-foaming baffle; 208-heat preservation door plate; 209-foaming heat preservation cover; 210-foaming fixing plate frame; 211-a storage rack; 213-storing a second drive motor; 214-drive a disc; 215-shifting fork; 216-storing a drive screw; 217-storage drive slots; 218-a drive wheels; 219-drive nut; 220-a guide sleeve; 222-supporting bars;
2051-b drive wheel; 2052-b driven wheel; 2053-b rotation axis; 2054-b swivel;
3-a nitrogen supply device; 4-a transfer tank; a 5-display; 6-an electrical box; 7-a liquid nitrogen filling valve; 9-moving wheels; 10-push handle.
Detailed Description
The technical scheme of the invention is further described below with reference to the embodiment and the attached drawings.
Examples
The embodiment provides a biological sample transferring and storing mechanism, which comprises a transferring box 1, a deep low-temperature storage tank 2 and a nitrogen supply device 3, wherein the transferring box 1 can be connected onto the deep low-temperature storage tank 2 in an abutting mode or separated from the deep low-temperature storage tank 2, and the transferring box 1 can transfer a received freezing pipe into the abutting-joint deep low-temperature storage tank 2; the nitrogen supply device 3 can supply nitrogen to the transfer box 1 and the cryogenic storage tank 2 respectively.
The transfer box 1 and the cryogenic storage tank 2 can be in butt joint or can be separated; when the frozen storage pipe is required to be extracted or placed, the transfer box 1 is conveyed to the deep low-temperature storage tank 2 which is required to be extracted or stored by utilizing an automatic guide transport vehicle, a plurality of deep low-temperature storage tanks 2 are arranged in a storage warehouse, and each deep low-temperature storage tank 2 can be respectively in butt joint with or separated from the transfer box 1; after the transfer box 1 is in butt joint with the target cryogenic storage tank 2 to form a whole, the nitrogen supply device 3 supplies nitrogen to the transfer box 1 fully so that the transfer box 1 is always in the cryogenic storage environment, and the transfer box 1 transfers the received frozen storage pipe into the cryogenic storage tank 2; the nitrogen supply device 3 can supply nitrogen to the transfer box 1 after the transfer box 1 is in butt joint with the cryogenic storage tank 2, or can be a nitrogen supply device which is arranged in the transfer box 1, and is not limited; it is preferable that the nitrogen supply device 3 is arranged on the cryogenic storage tank 2 and can supply nitrogen to the transfer box 1, and when the transfer box 1 is in butt joint with the cryogenic storage tank 2, the nitrogen supply device 3 supplies nitrogen to the transfer box 1, so that the nitrogen supply device 3 of the cryogenic storage tank 2 can be utilized in various aspects, and the transfer box 1 is convenient to transport; when the biological sample is stored and transferred, the freezing tube of the biological sample is firstly stored in the transfer tank 4, the transfer tank 4 can refrigerate the biological sample, and the transfer tank 4 is put into the transfer box 1 for transportation, so that after the transfer box 1 is in butt joint with the cryogenic storage tank 2 for nitrogen supply, the whole-process cold chain is ensured; in the whole extraction or storage process, the biological sample is always in a deep low-temperature environment, so that the safety of the biological sample storage is greatly improved.
In a preferred further implementation of the present embodiment, the transfer box 1 includes a transfer box housing 101, a receiving door 102, a docking door 103, an operation box 104, a pipe taking member 105, and a transfer shovel member 106; the transfer box shell 101 is provided with a receiving door 102 and a butt joint door 103, and the butt joint door 102 is arranged on the end surface of the transfer box 1, which is in butt joint with the cryogenic storage tank 2; the operation box 104, the pipe taking component 105 and the transferring and shoveling component 106 are all arranged in the transferring box shell 101, a freezing pipe or a transferring tank with biological samples can enter the operation box 104 through the receiving door 102, the transferring and shoveling component 106 can shoveling the freezing pipe storage disc 107 in the cryogenic storage tank 2 through the butt joint door 103, and the pipe taking component 105 can extract the freezing pipe in the operation box 104 into the freezing pipe storage disc 107 on the transferring and shoveling component 106. A plurality of storage areas 201 are arranged in the cryogenic storage tank 2, a plurality of freezing storage pipe storage discs 107 are arranged in the storage areas 201, and a plurality of freezing storage pipes can be placed in the freezing storage pipe storage discs 107.
The transfer box 1 further comprises a transfer tank temporary storage rack 108, a storage plate 109, a visual window 110 and an operation inlet 111; an operation inlet 111 is formed in the transfer box shell 101, and a visual window 110 is formed in the transfer box shell 101 above the operation inlet 11; the transfer tank temporary storage rack 108 is disposed in the transfer tank housing 101 and corresponds to the receiving door 102, the storage plate 109 is disposed in the operation box 104, and the storage plate 109 can store the freezing storage tray 107.
When the biological samples are required to be stored, firstly, the extracted biological samples are stored in a freezing pipe, the freezing pipe is placed in the transfer tank 4, and the transfer tank 4 is placed in a transfer tank temporary storage frame 108 in the transfer box 1 through a receiving door 102; then the transfer box 1 is conveyed to the corresponding deep low-temperature storage tank 2 through an automatic guide transport vehicle, and is in butt joint with the transfer box 1 into a whole, after the butt joint, nitrogen is supplied to the transfer box 1 by using the nitrogen supply device 3, and after the nitrogen supply is finished; an operator inserts his hand into the transfer box 1 through the operation entrance 111, opens the transfer tank 4 as viewed through the viewing window 110, and places the freezing pipe storage tray 107 having the freezing pipe stored in the transfer tank 4 on the storage plate 109; then the pipe taking component 105 stretches the pipe taking head into the operation box 104 for nitrogen dipping treatment, so that the pipe taking head is in a deep low-temperature state; in the above process, after the transfer box 1 is in butt joint with the cryogenic storage tank 2, the transfer shoveling member 106 in the transfer box 1 passes through the butt joint door 103 and stretches into the cryogenic storage tank 2, the freezing storage pipe storage tray 107 in the transfer box 1 is shoveled out, the shoveling is carried into the transfer box 1, the pipe taking member 105 sucks the freezing storage pipe on the storage plate 109 into the freezing storage pipe storage tray 107 on the transfer shoveling member 106 after the pipe head is subjected to nitrogen dipping treatment, and after the suction transfer is finished, the transfer shoveling member 106 shovels the freezing storage pipe storage tray 107 with the freezing storage pipe back into the cryogenic storage tank 2 for storage; likewise, if it is desired to extract the relevant cryopreservation vessel from cryogenic storage tank 2, it can be extracted by the reverse process described above. Here, the shape of the storage tray for the freezing pipe on the storage plate 109 may be different from that of the storage tray for the freezing pipe on the shovel transporting and conveying member, as long as the condition for storing the freezing pipe is satisfied.
The setting of the temporary storage rack 108 for transfer cans in the operation box 104 is not limited, and the temporary storage rack may be a temporary storage tank or a temporary storage plate, or the transfer cans may be temporarily placed in the operation box directly; the operation inlet 111 may be provided in various ways, but is not limited thereto, and the present embodiment discloses the following two arrangements: one is, the operation inlet 111 includes a first inlet 112, a second inlet 113, a first inlet door, and a second inlet door; the first extending port 112 and the second extending port 113 are directly arranged on the transfer box shell 101 according to the size that a human hand can extend into, and the first extending door and the second extending door are respectively arranged on the first extending port 112 and the second extending port 113; when the transfer box 1 is supplied with nitrogen, the first extending door and the second extending door are opened, hands are extended into the frozen storage tube storage disc 107 in the transfer box to the storage plate 109, and the first extending door and the second extending door are closed after the operation, so that the tightness is ensured; alternatively, the operation inlet 111 includes a first inlet 112, a second inlet 113, a first glove and a second glove; the first extending port and the second extending port are directly arranged on the transfer box shell 101 according to the size that a human hand can extend into, the first extending port 112 and the second extending port 113 are respectively provided with a first extending glove and a second extending glove in a sealing mode, and when the operation is needed, an operator can operate in the transfer box 1 through the first extending glove and the second extending glove which are sealed on the belts of the first extending port 112 and the second extending port 113 due to the fact that the gloves are arranged on the two extending ports in a sealing mode.
The arrangement of the transfer box 1 is further disclosed, a nitrogen outlet 114 is formed in the upper end face of the transfer box 1, and an air outlet valve 115 is arranged on the nitrogen outlet 114; the nitrogen supplying device 3 supplies nitrogen into the operation box 104. The nitrogen supplying device 3 directly connects the nitrogen supplying device in the transfer box 1 with the operation box 104 in the transfer box, so that the freezing storage tube is more directly contacted with the deep low-temperature environment, and the tube head is more convenient to pick up nitrogen. The nitrogen outlet 114 is formed in the upper end face of the transfer box 1, the nitrogen supply device 3 supplies nitrogen to the operation box 104 in the transfer box 1, after the nitrogen reaches a certain position, the nitrogen is discharged from the air outlet valve 115 of the nitrogen outlet 114, and at the moment, the operator can operate through the operation inlet 111 after judging that the nitrogen supply is finished.
Further disclosed is a control system; the control system can control the transfer box 1, the cryogenic storage tank 2 and the nitrogen supply device 3; a display 5 is arranged on the cryogenic storage tank 2, a code scanning component 116 is arranged in the transfer box 1, and the display 5 and the code scanning component 116 are electrically connected with the control system; the code scanning component 116 can scan the code of the freezing storage tube transferred into the cryogenic storage tank 2 and display the code on the display 5. As shown in fig. 3, the cryogenic storage tank 2 is provided with a control unit of a control system such as an electrical box 6, and the control system controls the display 5, the code scanning member 116, and the like;
The code scanning component 116 arranged in the transfer box 1 can scan codes of the frozen storage pipes to be stored or called, and the control system can process and store the code scanning results and can display the code scanning results on the display 5; when the pipe taking member 105 extracts the frozen storage pipes on the storage plate 109, the frozen storage pipes are firstly extracted and moved to the code scanning member 116, and the code scanning member 116 scans the codes and then transfers the codes to the frozen storage pipe storage plate 107 on the transferring and shoveling member 106.
A liquid nitrogen filling valve 7 is arranged on the cryogenic storage tank 2, and a liquid nitrogen butt joint hole is arranged on the transfer box shell 101; the liquid nitrogen filling valve 7 outwards extends and is provided with a first drying pipe, the first drying pipe accessible liquid nitrogen butt joint hole with the operation box 104 communicates, the liquid nitrogen filling valve 7 outwards extends and is provided with a second drying pipe, the second drying pipe with inside intercommunication of cryogenic storage jar 2. When an experimenter needs to store a certain amount of frozen storage pipes, firstly, the experimenter puts the frozen storage pipes into a frozen storage pipe storage disc 107 and transfers the frozen storage pipes into a transfer tank 4, the experimenter opens a cover of the transfer tank 4, puts the transfer tank 4 into a transfer box 1 through a receiving door 102, and after a docking door 103 is closed, the transfer box 1 is automatically guided to dock with a target cryogenic storage tank 2 in a transport vehicle, and when docking is performed, a liquid nitrogen docking hole is formed in a transfer box shell 101, and a first drying pipe extending from a nitrogen supply valve 7 of the cryogenic storage tank 2 is docked with the liquid nitrogen docking hole; the liquid nitrogen filling valve 7 is controlled to be started through the display 5, nitrogen is filled into the operation box in the transfer box shell 101 through the first drying pipe, the liquid nitrogen filling valve is stopped after the liquid nitrogen filling valve reaches a certain position, and the nitrogen is discharged from the air outlet valve 115; and then manually operated again through the operating population 111. The liquid nitrogen filling valve 7 is provided with a second drying pipe in an outward extending way for supplying nitrogen to the inside of the cryogenic storage tank 2.
This example further discloses an implementation of the transfer shovel member 106, where the transfer shovel member 106 includes a lifting pushing assembly 161, an axial pushing assembly 162, and a tray 163; the lifting pushing assembly 161 comprises a lifting driving motor 164 and a lifting screw 165, and the lifting driving motor 164 drives the lifting screw 165 to rotate; the axial push assembly 162 includes an axial drive member 166, an axial support plate 167, an axial socket 168, an axial drive bottom rail 169, an axial slide member 170, and an axial drive member 171; a screw nut 172 is arranged at the upper end of the axial supporting plate 167, and the screw nut 172 is in threaded connection with the lifting screw 165; the lower end of the axial supporting plate 167 is fixed with the axial bearing seat 168, the axial transmission bottom rail 169 is arranged on the axial bearing seat 168, the axial driving member 166 drives the axial driving member 171, and the axial sliding member 170 slides on the axial transmission bottom rail 169 under the driving of the axial driving member 171; the tray 163 is disposed on the axial slider 170.
The upper end of the axial supporting plate 167 is provided with a screw nut 172, the screw nut 172 is in threaded connection with the lifting screw 165, and the lifting driving motor 164 drives the lifting screw 165 to rotate and drive the axial supporting plate 167 to move up and down, so as to drive the whole axial pushing assembly 162 to move up and down; the axial driving member 166 drives the axial driving member 171, and the axial driving member 171 drives the axial sliding member 170 to move, thereby driving the tray 163 to move in the axial direction; thereby effecting up-and-down and axial movement of the tray 163.
In a preferred further implementation of this embodiment, the axial transmission member 171 includes a first driving wheel 173, a second driving wheel 174, a first driven wheel 175, a second driven wheel 176, a first driving chain 177 and a second driving chain 178; the axial driving member 166 comprises an axial driving motor 179, an axial driving wheel 180 and a driving chain 181; the axial transmission bottom rail 169 is a concave rail, a motor shaft of the axial driving motor 179 is coaxially connected with the axial driving wheel 180, and the axial driving wheel 180 is connected with the first driving wheel 173 through a driving chain; a driving connection shaft is coaxially arranged between the first driving wheel 173 and the second driving wheel 174, the driving connection shaft is rotatably arranged on the axial transmission bottom rail 169, and the first driving wheel 173 and the second driving wheel 174 are symmetrically arranged on two sides of the front end of the axial transmission bottom rail 169; the first driving wheel 173 is in transmission connection with the first driven wheel 175 through a first driving chain 177, and the second driving wheel 174 is in transmission connection with the second driven wheel 176 through a second driving chain 178; a first driving plate 183 is fixedly arranged on the first driving chain 177, and a second driving plate 184 is fixedly arranged on the second driving chain 178; the axial sliding member 170 includes an axial sliding plate 185 and an axial sliding wheel, the axial sliding plate 185 is slidably disposed on the upper end surface of the axial transmission bottom rail 169, the axial sliding wheel is rotatably disposed on the lower end surface of the axial sliding plate 185, and the axial sliding wheel is located in the groove of the axial transmission bottom rail 169 to slide; the first driving plate 183 and the second driving plate 184 respectively act on the axial sliding plate 185; the tray 163 is disposed at an end of the axial slide plate 185 remote from the axial driver 166.
The axial driving motor 179 drives the axial driving wheel 180 to rotate, the axial driving wheel 180 drives the first driving wheel 173 to rotate through the driving chain 181, the first driving wheel 173 drives the second driving wheel 180 to rotate through the driving connecting shaft, the first driving wheel 173 and the second driving wheel 180 respectively drive the first driving driven wheel 175 and the second driving driven wheel 176, meanwhile, the first driving chain 177 and the second driving chain 178 are transmitted, the first driving plate 184 arranged on the first driving chain 177 also rotates along with the rotation, and the second driving plate 184 arranged on the second driving chain 178 also rotates along with the rotation; the first driving plate 183 and the second driving plate 184 respectively act on the axial sliding plate 185, so that the first driving plate 183 and the second driving plate 184 drive the axial sliding plate 185 to slide, thereby driving the tray 163 to perform telescopic motion in the axial direction. Here, the tray 163 is provided in a fan shape that fits the freezing tube storage tray 107. It should be noted that, as shown in fig. 7, the first driving plate 183 is not directly connected to the axial sliding plate 185, but only a simplified schematic diagram is shown, and various schemes such as directly connecting the axial sliding plate 185 with the first driving plate 183 by the arrangement connection member shown in fig. 7 are possible, which will not be repeated here.
This example further discloses a preferred embodiment of the tube picking member 105, wherein the tube picking member 105 comprises a tube picking fixing frame 1051, a tube picking driving sliding table 1052, a tube picking sliding plate 1053, a tube picking sensing plate 1054, a tube picking first sensor 1055, a tube picking second sensor 1056, a sliding driving motor 1057 and a tube picking assembly; the tube taking fixing frame 1051 is fixed in the transfer box housing 101, the tube taking driving sliding table 1052 is arranged on the tube taking fixing frame 1051, the tube taking sliding plate 1053 is slidably arranged on the tube taking driving sliding table 1052, and the sliding driving motor 1057 drives the tube taking sliding plate 1053 to slide; the tube taking sensing plate 1054 is disposed on the tube taking sliding plate 1053, and the tube taking first sensor 1055 and the tube taking second sensor 1056 are disposed at two side ends of the tube taking driving sliding table 1052 respectively; the tube picking assembly is fixed with the tube picking sliding plate 1053; the tube taking assembly comprises a tube taking driving assembly 1059, a tube taking rotation shaft 1060, a tube taking receiving plate 1061 and a tube taking piece 1062, wherein the tube taking driving assembly 1059 is fixed with the tube taking sliding plate 1053, the tube taking rotation shaft 1060 is arranged on the tube taking driving assembly 1059, and the tube taking driving assembly 1059 drives the tube taking rotation shaft 1060 to rotate in the axial direction and the circumferential direction; one end of the tube taking receiving plate 1061 is connected to the tube taking rotating shaft 1060, the other end of the tube taking receiving plate 1061 is connected to the tube taking member 1062, and the tube taking member 1062 can suck the frozen tube.
The sliding driving motor 1057 drives the tube taking sliding plate 1053 to slide on the tube taking driving sliding table 1052, the tube taking sensing plate 1054 is arranged on the tube taking sliding plate 1053, when the tube taking sensing plate 1054 senses with the tube taking first sensor 1055, the tube taking sliding plate 1053 is indicated to move back to the original position, and when the tube taking sensing plate 1054 senses with the tube taking second sensor 1056, the tube taking sliding plate 1053 is indicated to reach a proper position when the tube taking assembly is driven to take tubes; that is, the first tube-taking sensor 1055 and the second tube-taking sensor 1056 form two location points; the tube picking assembly is arranged on the tube picking sliding plate 1053, so that the tube picking assembly moves under the drive of the tube picking sliding plate 1053; when the tube taking assembly is required to take out the frozen storage tubes, the tube taking assembly moves to a proper position (at the moment, the tube taking second sensor senses with the tube taking sensing plate) and stops, the tube taking driving assembly 1059 drives the tube taking pipe 1062 to enter the tube taking head of the tube taking pipe 1062 in the operation box 104 through the tube taking rotating shaft 1060 and the tube taking receiving plate 1061 to carry out nitrogen dipping operation, and then the tube taking pipe 1062 is utilized to extract the frozen storage tubes in the frozen storage tube storage tray 107 positioned on the storage plate into the frozen storage tube storage tray on the tray 163; after the complete extraction, the transfer shovel member 106 shovels it into the cryogenic storage pipe 2. The pipe taking piece can be a suction piece or a clamping piece and the like, so long as the carrying movement of the freezing storage pipe is achieved, and the details are not repeated here.
For the docking of the cryogenic storage tank 2 with the transfer box 1, a preferred further implementation of this embodiment, the cryogenic storage tank 2 comprises a rotary automatic door 202; the cryogenic storage tank 2 is provided with an access hole 203, the rotary automatic door 202 acts on the access hole 203, and the rotary automatic door 202 corresponds to the butt joint door 102; the rotary automatic door 202 comprises a speed reducing motor 204, a rotary door transmission assembly 205, a door body 206, a foaming baffle 207, a thermal insulation door plate 208, a foaming thermal insulation cover 209 and a foaming fixing plate frame 210; the thermal insulation door plate 208 is disposed on the door body 206, the foam fixing plate frame 210 is disposed at the periphery of the access hole 203, the foam thermal insulation cover 209 is disposed on the foam fixing plate frame 210 and covers the access hole 203, and the foam baffle 207 is disposed on the foam thermal insulation cover 209; a door hole is formed through the foaming baffle 207 and the foaming heat preservation cover 209, and the door body 206 is covered on the door hole; the gear motor 204 drives the door body 206 to open or close by driving the rotary door driving assembly 205.
When the transfer box 1 is in butt joint with the cryogenic storage tank 2, the control system controls the speed reducing motor 204 to be started, the speed reducing motor 204 can drive the door body 206 to be started through driving the rotary door transmission assembly 205, and the butt joint door 103 is started at the moment; and carrying out transfer operation after opening. The foaming baffle 207, the thermal insulation door plate 208, the foaming thermal insulation cover 209 and the foaming fixing plate frame 210 are arranged to improve the sealing property and the thermal insulation property of the cryogenic storage tank 2.
The further revolving door transmission assembly 205 includes a b driving wheel 2051, a b driven wheel 2052, a b rotating shaft 2053, and a b rotating seat 2054; the motor shaft of the gear motor 204 is coaxially connected with the b driving wheel 2051, the b driving wheel 2051 is meshed with the b driven wheel 2052, the b driven wheel 2051 is connected with one end of the b rotating shaft 2053, the other end of the b rotating shaft 2053 is connected with a b rotating seat 2054, and the b rotating seat 2054 is connected with the door body 206.
The embodiment preferably further discloses an implementation manner of the cryogenic storage tank, the cryogenic storage tank 2 further comprises a storage rack 211, a storage first driving motor, a storage second driving motor 213, a driving disk 214, a fork 215 and a storage driving screw 216; a storage driving groove 217 is formed in the middle of the storage rack 211 downwards, the lower end of the shifting fork 215 is fixed in the storage driving groove 217, a driving disc 214 is fixedly arranged at the upper end of the shifting fork 215, an A driving wheel 218 is arranged on a motor shaft of a first storage driving motor in an outward extending mode, and the A driving wheel 218 is in gear engagement connection with the driving disc 214; the motor shaft of the storage second driving motor 213 extends outwards to form a storage driving screw 216, the storage driving screw 216 passes through the driving disc 214 and the shifting fork 215 to extend into the storage driving groove 217, a driving nut 219 is provided on the bottom wall of the storage driving groove 217, and the storage driving screw 216 is in threaded connection with the driving nut 219.
The lower end of the fork 215 is fixed in the storage driving groove 217, and two guide sleeves 220 may be provided at the bottom of the storage driving groove 217 to fix the fork 215 to the storage driving groove 217 through the guide sleeves 220 for improving stability.
The storage second driving motor 213 is coaxially connected with the storage driving screw rod 216, and when the storage second driving motor 213 drives the storage driving screw rod 216 to rotate, the storage driving screw rod 216 is in threaded connection with the driving nut 219 at the bottom wall of the storage driving groove 217, so as to drive the storage rack 211 to move up and down;
The first storage driving motor drives the driving disc 214 to rotate through the A driving wheel 218, so that the fork 215 fixed in the storage driving groove 217 drives the storage rack 211 to rotate;
The storage rack 211 is provided with a plurality of storage areas 201, each storage area 201 is provided with a plurality of supporting bars 222, and the supporting bars 222 which are symmetrical in pairs can support and store one freezing plate storage tray 107; when the transfer shovel member 106 shovels the freezing tube storage tray 107 in the storage area, the corresponding freezing tube storage tray 107 is moved to a position corresponding to the rotary automatic door 202 by the up-down and rotary movement of the storage rack 211, after the rotary automatic door 202 is opened, the transfer shovel member 106 firstly stretches the tray 163 below the target freezing plate storage tray 107, and then micro-drives the height of the tray 163 to hold the freezing tube storage tray 107 and shovel the freezing tube storage tray.
In a preferred further implementation manner of this embodiment, a moving wheel 9 is disposed at the lower end of the cryogenic storage tank 2, and a pushing handle 10 is disposed on an end surface of the cryogenic storage tank 2 away from the transfer box 1. When necessary, the cryogenic storage tank 2 can be moved by manually pushing the push handle 10 and using the moving wheel 9. Flexibility is increased.
The sequence of the above embodiments is only for convenience of description, and does not represent the advantages and disadvantages of the embodiments.
Finally, it should be noted that: the above embodiments are only for illustrating the technical solution of the present invention, and are not limiting; although the invention has been described in detail with reference to the foregoing embodiments, it will be understood by those of ordinary skill in the art that: the technical scheme described in the foregoing embodiments can be modified or some technical features thereof can be replaced by equivalents; such modifications and substitutions do not depart from the spirit and scope of the technical solutions of the embodiments of the present invention.
Claims (6)
1. A biological sample transferring and storing mechanism, which is characterized by comprising a transferring box, a deep low-temperature storage tank and a nitrogen supply device, wherein the transferring box can be connected to the deep low-temperature storage tank in an abutting mode or separated from the deep low-temperature storage tank in a relatively deep low-temperature mode, and the transferring box can transfer a received frozen storage pipe into the abutting-joint deep low-temperature storage tank;
the nitrogen supply device can respectively supply nitrogen to the transfer box and the deep low-temperature storage tank;
The transfer box comprises a transfer box shell, a receiving door, a butt joint door, an operation box, a pipe taking component and a transfer shoveling component;
the transfer box shell is provided with a receiving door and a butt joint door, and the butt joint door is arranged on the end surface of the transfer box, which is in butt joint with the deep low-temperature storage tank; the operation box, the pipe taking component and the transferring shoveling component are all arranged in the transferring box shell,
The frozen storage pipe or the transfer tank with biological samples can enter the operation box through a receiving door, the transfer shoveling and conveying member can pass through the butt joint door to shovel and convey the frozen storage pipe storage disc in the cryogenic storage tank, and the pipe taking member can extract the frozen storage pipe in the operation box into the frozen storage pipe storage disc on the transfer shoveling and conveying member;
The transfer box further comprises a transfer tank temporary storage frame, a storage plate, a visual window and an operation inlet;
An operation inlet is formed in the transfer box shell, and a visual window is formed in the transfer box shell above the operation inlet;
The transfer tank temporary storage frame is arranged in the transfer box shell and corresponds to the receiving door, the storage plate is arranged in the operation box, and the storage plate can store a freezing storage pipe storage disc;
the transferring shovel component comprises a lifting pushing component, an axial pushing component and a tray;
the lifting pushing assembly comprises a lifting driving motor and a lifting screw rod, and the lifting driving motor drives the lifting screw rod to rotate;
the axial pushing assembly comprises an axial driving piece, an axial supporting plate, an axial bearing seat, an axial transmission bottom rail, an axial sliding piece and an axial transmission piece;
A screw nut is arranged at the upper end of the axial supporting plate and is in threaded connection with the lifting screw; the lower end of the axial supporting plate is fixed with the axial bearing seat, the axial transmission bottom rail is arranged on the axial bearing seat, the axial driving piece drives the axial transmission piece, and the axial sliding piece moves on the axial transmission bottom rail under the drive of the axial transmission piece; the tray is arranged on the axial sliding piece;
The axial transmission part comprises a first driving wheel, a second driving wheel, a first driven wheel, a second driven wheel, a first driving chain and a second driving chain; the axial driving piece comprises an axial driving motor, an axial driving wheel and a driving chain;
The axial transmission bottom rail is a concave rail, a motor shaft of the axial driving motor is coaxially connected with the axial driving wheel, and the axial driving wheel is connected with the first driving wheel through a driving chain; a drive connecting shaft is coaxially arranged between the first drive wheel and the second drive wheel, the drive connecting shaft is rotatably arranged on the axial transmission bottom rail, and the first drive wheel and the second drive wheel are symmetrically arranged on two sides of the front end of the axial transmission bottom rail; the first driving wheel is in transmission connection with the first driven wheel through a first driving chain, and the second driving wheel is in transmission connection with the second driven wheel through a second driving chain; the first driving chain is fixedly provided with a first driving plate, and the second driving chain is fixedly provided with a second driving plate;
The axial sliding part comprises an axial sliding plate and an axial sliding wheel, the axial sliding plate is slidably arranged on the upper end face of the axial transmission bottom rail, the axial sliding wheel is rotatably arranged on the lower end face of the axial sliding plate, and the axial sliding wheel is positioned in a groove of the axial transmission bottom rail to slide; the first driving plate and the second driving plate respectively act on the axial sliding plate; the tray is arranged at one end of the axial sliding plate far away from the axial driving piece;
The tube taking component comprises a tube taking fixing frame, a tube taking driving sliding table, a tube taking sliding plate, a tube taking induction plate, a tube taking first sensor, a tube taking second sensor, a sliding driving motor and a tube taking assembly;
The tube taking fixing frame is fixed in the transfer box shell, the tube taking driving sliding table is arranged on the tube taking fixing frame, the tube taking sliding plate is slidably arranged on the tube taking driving sliding table, and the sliding driving motor drives the tube taking sliding plate to slide; the tube taking induction plate is arranged on the tube taking sliding plate, and the tube taking first sensor and the tube taking second sensor are respectively arranged at two side ends of the tube taking driving sliding table; the tube taking assembly is fixed with the tube taking sliding plate;
the tube taking assembly comprises a tube taking driving assembly, a tube taking rotating shaft, a tube taking receiving plate and a tube taking piece, wherein the tube taking driving assembly is fixed with the tube taking sliding plate, the tube taking rotating shaft is arranged on the tube taking driving assembly, and the tube taking driving assembly drives the tube taking rotating shaft to rotate in the axial direction and the circumferential direction;
One end of the tube taking receiving plate is connected with the tube taking rotating shaft, the other end of the tube taking receiving plate is connected with the tube taking piece, and the tube taking piece can absorb the frozen tube;
The deep low-temperature storage tank further comprises a storage rack, a storage first driving motor, a storage second driving motor, a driving disc, a fork pulling piece and a storage driving screw rod;
The middle part of the storage rack is provided with a storage driving groove downwards, the lower end of the shifting fork piece is fixed in the storage driving groove, the upper end of the shifting fork piece is fixedly provided with a driving disc, a motor shaft of the storage first driving motor is provided with an A driving wheel in an outward extending mode, and the A driving wheel is in meshed connection with the driving disc;
The motor shaft of the storage second driving motor extends outwards to be provided with a storage driving screw rod, the storage driving screw rod penetrates through the driving disc and the shifting fork piece to extend into the storage driving groove, a driving nut is upwards arranged on the bottom wall of the storage driving groove, and the storage driving screw rod is in threaded connection with the driving nut.
2. The biological sample transferring and storing mechanism according to claim 1, wherein a nitrogen outlet is formed in the upper end face of the transferring box, and an air outlet valve is arranged on the nitrogen outlet; the nitrogen supplying device supplies nitrogen to the operation box.
3. The biological sample transfer and storage mechanism of claim 2, wherein the cryogenic storage tank comprises a rotary automatic door; the deep low-temperature storage tank is provided with an access hole, the rotary automatic door acts on the access hole, and the rotary automatic door corresponds to the butt joint door;
The rotary automatic door comprises a speed reducing motor, a rotary door transmission assembly, a door body, a foaming baffle plate, a heat-preserving door plate, a foaming heat-preserving cover and a foaming fixing plate frame; the heat-insulating door plate is arranged on the door body, the foaming fixing plate frame is arranged on the periphery of the access hole, the foaming heat-insulating cover is arranged on the foaming fixing plate frame and covers the access hole, and the foaming baffle is arranged on the foaming heat-insulating cover; a door hole is formed through the foaming baffle plate and the foaming heat preservation cover, and the door body is covered on the door hole;
The speed reducing motor can drive the door body to open or close through driving the rotary door transmission assembly.
4. The biological sample transport storage mechanism of claim 2, further comprising a control system; the control system can control the transfer box, the deep low-temperature storage tank and the nitrogen supply device;
A display is arranged on the cryogenic storage tank, a code scanning component is arranged in the transfer box, and the display and the code scanning component are electrically connected with the control system; the code scanning component can scan codes of the freezing storage pipes transferred into the deep low-temperature storage tank and display the codes on the display.
5. The biological sample transfer and storage mechanism according to claim 4, wherein a liquid nitrogen filling valve is arranged on the cryogenic storage tank, and a liquid nitrogen butt joint hole is arranged on the transfer box shell;
The liquid nitrogen filling valve outwards extends and is provided with a first drying pipe, the first drying pipe accessible liquid nitrogen butt joint hole with the operation box intercommunication, the liquid nitrogen filling valve outwards extends and is equipped with the second drying pipe, the second drying pipe with inside intercommunication of dark low temperature holding vessel.
6. The biological sample transfer and storage mechanism of claim 1, wherein the lower end of the cryogenic storage tank is provided with a moving wheel, and the end surface of the cryogenic storage tank far from the transfer box is provided with a pushing handle.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811424516.3A CN109399043B (en) | 2018-11-27 | 2018-11-27 | Biological sample transferring and storing mechanism |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811424516.3A CN109399043B (en) | 2018-11-27 | 2018-11-27 | Biological sample transferring and storing mechanism |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN109399043A CN109399043A (en) | 2019-03-01 |
| CN109399043B true CN109399043B (en) | 2024-04-19 |
Family
ID=65455840
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201811424516.3A Active CN109399043B (en) | 2018-11-27 | 2018-11-27 | Biological sample transferring and storing mechanism |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN109399043B (en) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110436027B (en) * | 2019-09-20 | 2024-04-26 | 上海原能细胞生物低温设备有限公司 | System for storing biological samples |
| CN110786316A (en) * | 2019-10-22 | 2020-02-14 | 内蒙古金草原牧业有限公司 | Beef cattle propagation embryo cryopreservation device |
| CN111377184B (en) * | 2020-04-27 | 2024-06-21 | 上海原能细胞生物低温设备有限公司 | Sample transferring operation cabin |
| CN112499081B (en) * | 2020-12-07 | 2024-06-21 | 上海原能细胞生物低温设备有限公司 | Whole plate type sample access system |
| CN113148417B (en) * | 2021-05-11 | 2024-06-21 | 上海原能细胞生物低温设备有限公司 | Intelligent storage device and storage method using sample storage box |
| CN113501247A (en) * | 2021-08-26 | 2021-10-15 | 义乌市铂玥信息技术咨询有限公司 | Rotary cage type ultralow-temperature biological sample automatic storing and taking system |
| CN117104748A (en) * | 2023-09-11 | 2023-11-24 | 上海原能细胞生物低温设备有限公司 | Biological sample storage method and automatic storage equipment thereof |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101970957A (en) * | 2008-01-25 | 2011-02-09 | 汉密尔顿存储技术公司 | Automated storage and retrieval system for storing biological or chemical samples at ultra-low temperatures |
| CN105857937A (en) * | 2016-04-28 | 2016-08-17 | 上海原能健康管理有限公司 | Liquid nitrogen cylinder, cryogenic vial storing and fetching device and liquid nitrogen cylinder storing and fetching system |
| CN105857932A (en) * | 2016-04-28 | 2016-08-17 | 上海原能健康管理有限公司 | Liquid nitrogen container and cryogenic vial pick-and-place device |
| CN206284224U (en) * | 2016-12-19 | 2017-06-30 | 郑州大学 | A kind of stem cell refrigerated transport case |
| CN207275387U (en) * | 2017-09-21 | 2018-04-27 | 基点维科(成都)医疗机器人技术有限公司 | Biological specimen low temperature accesses tank |
| CN207404319U (en) * | 2017-09-21 | 2018-05-25 | 基点维科(成都)医疗机器人技术有限公司 | Cdna sample transmits storehouse |
| CN209291249U (en) * | 2018-11-27 | 2019-08-23 | 上海原能细胞生物低温设备有限公司 | A kind of biological sample transhipment stocking mechanism |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2017606A1 (en) * | 2007-07-16 | 2009-01-21 | Commissariat A L'energie Atomique | Method and gripping device for automatically transferring a sample container from a storing location to an analysis location, and use of said device |
| JP6177216B2 (en) * | 2014-10-31 | 2017-08-09 | 株式会社椿本チエイン | Low temperature storage system, transfer mechanism, and low temperature hangar |
| CN105857941B (en) * | 2016-04-28 | 2018-06-29 | 上海原能健康管理有限公司 | Cryopreservation tube access device |
-
2018
- 2018-11-27 CN CN201811424516.3A patent/CN109399043B/en active Active
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101970957A (en) * | 2008-01-25 | 2011-02-09 | 汉密尔顿存储技术公司 | Automated storage and retrieval system for storing biological or chemical samples at ultra-low temperatures |
| CN105857937A (en) * | 2016-04-28 | 2016-08-17 | 上海原能健康管理有限公司 | Liquid nitrogen cylinder, cryogenic vial storing and fetching device and liquid nitrogen cylinder storing and fetching system |
| CN105857932A (en) * | 2016-04-28 | 2016-08-17 | 上海原能健康管理有限公司 | Liquid nitrogen container and cryogenic vial pick-and-place device |
| CN206284224U (en) * | 2016-12-19 | 2017-06-30 | 郑州大学 | A kind of stem cell refrigerated transport case |
| CN207275387U (en) * | 2017-09-21 | 2018-04-27 | 基点维科(成都)医疗机器人技术有限公司 | Biological specimen low temperature accesses tank |
| CN207404319U (en) * | 2017-09-21 | 2018-05-25 | 基点维科(成都)医疗机器人技术有限公司 | Cdna sample transmits storehouse |
| CN209291249U (en) * | 2018-11-27 | 2019-08-23 | 上海原能细胞生物低温设备有限公司 | A kind of biological sample transhipment stocking mechanism |
Also Published As
| Publication number | Publication date |
|---|---|
| CN109399043A (en) | 2019-03-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN109399043B (en) | Biological sample transferring and storing mechanism | |
| CN209291249U (en) | A kind of biological sample transhipment stocking mechanism | |
| JP3235995U (en) | Biological sample storage | |
| CN109292448B (en) | Intelligent biological sample storing and taking mechanism | |
| CN106628783B (en) | Full-automatic ultra-low temperature honeycomb type biological sample storehouse | |
| CN109399044B (en) | Intelligent access system for biological samples | |
| CN108045765B (en) | Carousel formula low temperature deposits and gets integrative device | |
| US20120060520A1 (en) | Input/Output Module and Overall Temperature Control of Samples | |
| CN210203096U (en) | Liquid nitrogen storage device | |
| CN210213517U (en) | Liquid nitrogen storage device with automatic access function | |
| CN111776477B (en) | Body fluid collecting and storing device for clinical laboratory | |
| CN111907941A (en) | Liquid nitrogen storage system | |
| CN111908119A (en) | Low temperature transport method | |
| CN111907942A (en) | Liquid nitrogen storage device and using method thereof | |
| CN111903661B (en) | Liquid nitrogen storage device | |
| CN111907943A (en) | Liquid nitrogen storage device with automatic access function | |
| CN110511872A (en) | Cell batch automatic production equipment and its working method | |
| CN211353694U (en) | Program cooling and storage device | |
| CN113115764A (en) | Program cooling and storage device | |
| CN112208942B (en) | Access device | |
| CN110731333B (en) | Cell dispensing and storing device and method thereof | |
| CN111959953B (en) | Basket type sample low-temperature storage device | |
| CN212387099U (en) | Sample transfer operation cabin | |
| CN218184938U (en) | Semi-automatic whole plate type sample storing and taking equipment | |
| CN116588566A (en) | Truss machine liquid nitrogen tank group biological sample large warehouse |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |