CN106924335A - Traditional Chinese medicine emulsifiable paste that a kind for the treatment of is sprained and preparation method thereof - Google Patents
Traditional Chinese medicine emulsifiable paste that a kind for the treatment of is sprained and preparation method thereof Download PDFInfo
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/236—Ligusticum (licorice-root)
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- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
- A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
- A61K31/245—Amino benzoic acid types, e.g. procaine, novocaine
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/233—Bupleurum
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- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/32—Burseraceae (Frankincense family)
- A61K36/324—Boswellia, e.g. frankincense
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
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- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
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- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
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Abstract
The present invention relates to pharmaceutical technology field, and in particular to traditional Chinese medicine emulsifiable paste that a kind for the treatment of is sprained and preparation method thereof.The preparation method comprises the following steps：(1) by the traditional Chinese medicinal components of following weight portion：Ligusticum wallichii, radix bupleuri, Radix Angelicae Sinensis, frankincense, Radix Glycyrrhizae and the Radix Astragali, are ground into powder and obtain herb powder；By oil phase component raw material：Wintergreen and menthol mix to obtain oil mixture；By water phase components raw material：Chlorphenamine maleate, tetracaine hydrochloride, Carbomer and purified water, mix to obtain aqueous mixture；(2) oil mixture is added into aqueous mixture, adds herb powder, obtain medicinal mixture；(3) by medicinal mixture homogeneous, go out container and be aged the traditional Chinese medicine emulsifiable paste that must be treated and sprain.It is of the invention to treat the Radix Glycyrrhizae in the traditional Chinese medicine emulsifiable paste sprained to make medicine coordinating the drug actions of a prescription, and antiallergy is played with Radix Astragali collaboration, antipruritic effect, chlorphenamine maleate can also prevent allergy allergy, greatly reduce the allergy rate that traditional Chinese medicine emulsifiable paste of the present invention is used.
Description
Technical field
The present invention relates to pharmaceutical technology field, and in particular to traditional Chinese medicine emulsifiable paste that a kind for the treatment of is sprained and preparation method thereof.
Background technology
Acute soft tissue bruise, is skin, hypodermis, the musculature caused injury due to mechanicalness caused by the factor
Institutional framework is damaged and dysfunction.Injured the red, swollen, hot of part, pain, dysfunction etc. are shown as, serious has whole body anti-
Should, such as body temperature increases, the change of vital sign (breathing, blood pressure, pulse), is dehydrated, loses blood, kidney failure, fracture etc..Chronic soft group
Bruise is knitted, refers to the damage caused by chronic injury of locomotor system or acute soft tissue injury delay, onset is slow, and the course of disease is continuous
It is long.Such disease doctor trained in Western medicine often treats this disease with anti-inflammation analgesia medicine, and Long-term Oral is big to human body side effect.
Traditional Chinese medicine paste preparation technology is complicated, quality is difficult to control to, medicine utilization rate is low, in-convenience in use.And in
Ointment agent often long-time medication, local excitation is stronger, skin may be caused to itch, redden, the allergic phenomena such as purple plague purpura.
The content of the invention
To solve defect present in above-mentioned prior art, sprained it is an object of the invention to provide a kind of hypo-allergenic treatment
Traditional Chinese medicine emulsifiable paste preparation method.
The technical scheme is that providing a kind of preparation method of the traditional Chinese medicine emulsifiable paste treated and sprain, comprise the following steps：
(1) by the traditional Chinese medicinal components of following weight portion：2-3 parts of Ligusticum wallichii, 2-3 parts of radix bupleuri, 2-3 parts of Radix Angelicae Sinensis, 2-3 parts of frankincense, 1-2
Part Radix Glycyrrhizae and the 1-2 parts of Radix Astragali, are ground into powder and obtain herb powder；
By the oil phase component raw material of following weight portion：10-20 portions of wintergreen and 3-8 parts of menthol mix to obtain oil phase mixing
Thing；
By the water phase components raw material of following weight portion：0.3-0.5 parts of chlorphenamine maleate, 0.5-1 parts of tetracaine hydrochloride,
0.2-0.5 parts of Carbomer and 40-50 parts of purified water, mix to obtain aqueous mixture；
(2) oil mixture is slowly added into aqueous mixture at a temperature of 55-65 DEG C, the aqueous mixture keeps
500rpm stirrings add herb powder up to adding oil mixture, continue to stir 30 minutes, obtain medicinal mixture；
(3) medicinal mixture is cooled to 35-40 DEG C, homogeneous is carried out using high speed homogenization device, setting speed is 3000-
5000rpm, homogenizing time is 10-15 minutes, goes out container and is aged the traditional Chinese medicine emulsifiable paste that must be treated and sprain.
Preferably, in the preparation method of the traditional Chinese medicine emulsifiable paste that above-mentioned treatment is sprained, the herb powder, oil mixture and
The weight part ratio of aqueous mixture is：10：13：42.
Preferably, in the preparation method of the traditional Chinese medicine emulsifiable paste that above-mentioned treatment is sprained, the herb powder, oil mixture and
The weight part ratio of aqueous mixture is：14：28：52.
Preferably, in the preparation method of the traditional Chinese medicine emulsifiable paste that above-mentioned treatment is sprained, the step (3) is specially：By medicine
Mixture is cooled to 35-40 DEG C, adds the ethyl-para-hydroxybenzoate of medicinal mixture quality 0.2-0.5%, using equal at a high speed
Matter device carries out homogeneous, and setting speed is 3000rpm, and homogenizing time is 10-15 minutes, goes out container and is aged the Chinese medicine that must be treated and sprain
Emulsifiable paste.
Another technical scheme of the invention is prepared by the preparation method for providing the traditional Chinese medicine emulsifiable paste that a kind of above-mentioned treatment is sprained
Traditional Chinese medicine emulsifiable paste.
Beneficial effect of the present invention：The traditional Chinese medicine emulsifiable paste sprained for the treatment of of the invention is on the basis of Traditional Chinese Medicine diagnosis and treatment based on an overall analysis of the illness and the patient's condition
Developed with reference to clinical practice for many years, all medicine phases are closed has promoting blood circulation and removing blood stasis, inducing meastruation to relieve menalgia effect, treatment is sprained with treatment
Effect is definite, instant effect, cure rate is high, the advantages of have no toxic side effect.
In the traditional Chinese medicine emulsifiable paste that treatment of the invention is sprained, natural winter-green oil is applied to DOMS position, can promote pain
The blood Rapid Circulation at pain position, regulates channels and activates collateral, pain of alleviation；Each traditional Chinese medicinal components collaboration such as Ligusticum wallichii, radix bupleuri, Radix Angelicae Sinensis, frankincense
Play blood-activating and qi-promoting, wind-expelling pain-stopping, the effect that mitigation is sprained.
It is of the invention to treat the Radix Glycyrrhizae in the traditional Chinese medicine emulsifiable paste sprained to make medicine coordinating the drug actions of a prescription, and play anti-mistake with Radix Astragali collaboration
Quick, antipruritic effect, chlorphenamine maleate can also prevent allergy allergy, greatly reduce traditional Chinese medicine emulsifiable paste of the present invention and use
Allergy rate.
Specific embodiment
To describe technology contents of the invention, structural feature, the objects and the effects in detail, below in conjunction with implementation method
It is explained in detail.
Key ideas of the present invention：The Radix Glycyrrhizae treated in the traditional Chinese medicine emulsifiable paste sprained of the invention is to make medicine coordinating the drug actions of a prescription, and and
Antiallergy is played in Radix Astragali collaboration, and antipruritic effect, chlorphenamine maleate can also prevent allergy allergy, greatly reduces this
The allergy rate that invention traditional Chinese medicine emulsifiable paste is used.
The effect of inventive formulation key component is as follows：
Wintergreen, with anti-inflammatory analgesic effect, is applied to and sprains position, and the blood of painful area can be promoted quickly to follow
Ring, regulates channels and activates collateral, pain of alleviation.Ligusticum wallichii, effect is obtained with blood-activating and qi-promoting, wind-expelling pain-stopping.Menthol, acting on skin can produce
Strong refrigerant sense, can mitigate myalgia sense of discomfort and pain.Chlorphenamine maleate, with antihistaminicum H1 acceptors
Effect, Central nervous have stronger inhibitory action, prevent allergy allergy, greatly reduce the allergy that medicine is used
Rate.Tetracaine hydrochloride, it acts on skin peripheral nerve, and stabilization neural tissue cell film reduces sodium ion inflow, makes normal
Polarization replaces with depolarising is obstructed, and nerve impulse transmission cannot be carried out, and play analgesic effect.
Radix bupleuri：Sun is lifted in dispelling wind and heat from the body, soothing liver-qi stagnation, rising Yang, is applied to traumatic injury.
Radix Angelicae Sinensis：Replenishing and activating blood, menstruction regulating and pain relieving, ease constipation.
Frankincense：Promoting blood circulation, promoting qi circulation and relieving pain, detumescence and promoting granulation, this product are to treat the swollen regular supplies of traumatic injury, ulcer sore carbuncle.
Radix Glycyrrhizae, has functions that there is tonifying middle-Jiao and Qi, eliminating the phlegm removing toxic substances, mediation property of medicine.Modern pharmacology research finds, in Radix Glycyrrhizae
Contained glycyrrhizin, there is similar cortex hormone of aadrenaline, with antianaphylactic effect.
Radix Astragali major function is tonifying Qi and lifting yang, strengthening exterior and reducing sweat, torr sore myogenic, diuresis detumescence.Modern pharmacological research finds, yellow
The composition such as carbohydrate, lymphatic temperament, choline, glycine betaine and amino acid contained by stilbene, has stimulating central nervous system and similar adrenal cortex to swash
Element effect, has certain curative effect for anaphylactoid purpura, chronic urticaria and other anaphylaxis dermatosis.
Embodiment 1
A kind of preparation method for treating the traditional Chinese medicine emulsifiable paste sprained, comprises the following steps：
(1) by the traditional Chinese medicinal components of following weight portion：2kg Ligusticum wallichiis, 2kg radix bupleuri, 2kg Radix Angelicae Sinensis, 2kg frankincenses, 1kg Radix Glycyrrhizaes and
The 1kg Radixs Astragali, are ground into powder and obtain herb powder；
By the oil phase component raw material of following weight portion：10kg wintergreens and 3kg menthols mix to obtain oil mixture；
By the water phase components raw material of following weight portion：0.3kg chlorphenamine maleates, 0.5kg tetracaine hydrochlorides, 0.2kg
Carbomer and 40kg purified waters, mix to obtain aqueous mixture；
(2) oil mixture is slowly added into aqueous mixture at a temperature of 55-65 DEG C, the aqueous mixture keeps
500rpm stirrings add herb powder up to adding oil mixture, continue to stir 30 minutes, obtain medicinal mixture；
(3) medicinal mixture is cooled to 35-40 DEG C, homogeneous is carried out using high speed homogenization device, setting speed is 3000-
5000rpm, homogenizing time is 10-15 minutes, goes out container and is aged the traditional Chinese medicine emulsifiable paste that must be treated and sprain.
Embodiment 2
A kind of preparation method for treating the traditional Chinese medicine emulsifiable paste sprained, comprises the following steps：
(1) by the traditional Chinese medicinal components of following weight portion：3kg Ligusticum wallichiis, 3kg radix bupleuri, 3kg Radix Angelicae Sinensis, 3kg frankincenses, 2kg Radix Glycyrrhizaes and
The 2kg Radixs Astragali, are ground into powder and obtain herb powder；
By the oil phase component raw material of following weight portion：20kg wintergreens and 8kg menthols mix to obtain oil mixture；
By the water phase components raw material of following weight portion：0.5kg chlorphenamine maleates, 1kg tetracaine hydrochlorides, 0.5kg cards
Ripple nurse and 50kg purified waters, mix to obtain aqueous mixture；
(2) oil mixture is slowly added into aqueous mixture at a temperature of 55-65 DEG C, the aqueous mixture keeps
500rpm stirrings add herb powder up to adding oil mixture, continue to stir 30 minutes, obtain medicinal mixture；
(3) medicinal mixture is cooled to 35-40 DEG C, the ethyl-para-hydroxybenzoate of 0.3kg is added, using high speed homogenization
Device carries out homogeneous, and setting speed is 3000-5000rpm, and homogenizing time is 10-15 minutes, and going out container and be aged must treat what is sprained
Traditional Chinese medicine emulsifiable paste.
Embodiment 3
A kind of preparation method for treating the traditional Chinese medicine emulsifiable paste sprained, comprises the following steps：
(1) by the traditional Chinese medicinal components of following weight portion：2.5kg Ligusticum wallichiis, 2.5kg myrrhs, 2.5kg levisticums, 2.5kg safflowers,
1.5kg Radix Glycyrrhizaes and the 1.5kg Radixs Astragali, are ground into powder and obtain herb powder；
By the oil phase component raw material of following weight portion：15kg wintergreens and 5kg menthols mix to obtain oil mixture；
By the water phase components raw material of following weight portion：0.5kg chlorphenamine maleates, 0.8kg tetracaine hydrochlorides, 0.3kg
Carbomer and 45kg purified waters, mix to obtain aqueous mixture；
(2) oil mixture is slowly added into aqueous mixture at a temperature of 55-65 DEG C, the aqueous mixture keeps
500rpm stirrings add herb powder up to adding oil mixture, continue to stir 30 minutes, obtain medicinal mixture；
(3) medicinal mixture is cooled to 35-40 DEG C, the ethyl-para-hydroxybenzoate of 0.4kg is added, using high speed homogenization
Device carries out homogeneous, and setting speed is 5000rpm, and homogenizing time is 10-15 minutes, goes out container and is aged the Chinese medicine breast that must be treated and sprain
Cream.
Comparative example
(having lacked Radix Glycyrrhizae, the Radix Astragali and chlorphenamine maleate in simply raw material identical with the condition of embodiment 3)
A kind of preparation method for treating the traditional Chinese medicine emulsifiable paste sprained, comprises the following steps：
(1) by the traditional Chinese medicinal components of following weight portion：2.5kg Ligusticum wallichiis, 2.5kg myrrhs, 2.5kg levisticums, 2.5kg safflowers, powder
It is broken into powder and obtains herb powder；
By the oil phase component raw material of following weight portion：15kg wintergreens and 5kg menthols mix to obtain oil mixture；
By the water phase components raw material of following weight portion：0.8kg tetracaine hydrochlorides, 0.3kg Carbomers and 45kg purified waters, mix
Close to obtain aqueous mixture；
(2) oil mixture is slowly added into aqueous mixture at a temperature of 55-65 DEG C, the aqueous mixture keeps
500rpm stirrings add herb powder up to adding oil mixture, continue to stir 30 minutes, obtain medicinal mixture；
(3) medicinal mixture is cooled to 35-40 DEG C, the ethyl-para-hydroxybenzoate of 0.4kg is added, using high speed homogenization
Device carries out homogeneous, and setting speed is 5000rpm, and homogenizing time is 10-15 minutes, goes out container and is aged the Chinese medicine breast that must be treated and sprain
Cream.
Efficacy analysis：
Participate in the standard of respondent：It is diagnosed as and sprains patient.Age bracket is 30-60 Sui, and men and women does not limit.The sample of investigation
Quantity is 100.It is divided into 2 groups, every group of quantity 50, the Chinese medicine breast for respectively spraining the treatment of above-described embodiment 3 and comparative example
Cream is applied directly to two groups and sprains patient affected part, daily to smear 3 times.Continuously use 7 day time.
Evaluation criterion：After 7 days, by pay a return visit follow the trail of patient sprain with allergic symptom situation, be divided into engineering noise, " effective "
" allergy " three situations.The number of cases of each symptomatic condition is recorded respectively, and curative effect is as shown in table 1.
Table 1
| It is invalid | Effectively | Allergy | |
| Embodiment 3 | 2 | 48 | 0 |
| Comparative example | 3 | 47 | 2 |
Result of the test as can be seen from Table 1：The traditional Chinese medicine emulsifiable paste group treated and sprain of the present invention is smeared, after smearing 7 days, is had
38 patients show " effective " that overall effectively cure rate is 96%, and without allergic conditions.
In sum, good effect is sprained in the traditional Chinese medicine emulsifiable paste treatment that treatment of the invention is sprained, and penetration is strong, nontoxic
Side effect, is difficult allergy and easy to use, and men and women, old children are all suitable.
In the traditional Chinese medicine emulsifiable paste that treatment of the invention is sprained, natural winter-green oil is applied to DOMS position, can promote pain
The blood Rapid Circulation at pain position, regulates channels and activates collateral, pain of alleviation；Ligusticum wallichii, radix bupleuri, Radix Angelicae Sinensis, frankincense, each traditional Chinese medicinal components are cooperateed with
To the effect that blood-activating and qi-promoting, wind-expelling pain-stopping, mitigation are sprained.
It is of the invention to treat the Radix Glycyrrhizae in the traditional Chinese medicine emulsifiable paste sprained to make medicine coordinating the drug actions of a prescription, and play anti-mistake with Radix Astragali collaboration
Quick, antipruritic effect, chlorphenamine maleate can also prevent allergy allergy, greatly reduce traditional Chinese medicine emulsifiable paste of the present invention and use
Allergy rate.
Embodiments of the invention are the foregoing is only, the scope of the claims of the invention is not thereby limited, it is every to utilize this hair
Equivalent structure or equivalent flow conversion that bright description is made, or directly or indirectly it is used in other related technology necks
Domain, is included within the scope of the present invention.
Claims (5)
1. it is a kind of to treat the preparation method of traditional Chinese medicine emulsifiable paste sprained, it is characterised in that to comprise the following steps：
(1) by the traditional Chinese medicinal components of following weight portion：2-3 parts of Ligusticum wallichii, 2-3 parts of radix bupleuri, 2-3 parts of Radix Angelicae Sinensis, 2-3 parts of frankincense, 1-2 parts it is sweet
Grass and the 1-2 parts of Radix Astragali, are ground into powder and obtain herb powder；
By the oil phase component raw material of following weight portion：10-20 portions of wintergreen and 3-8 parts of menthol mix to obtain oil mixture；
By the water phase components raw material of following weight portion：0.3-0.5 parts of chlorphenamine maleate, 0.5-1 parts of tetracaine hydrochloride, 0.2-
0.5 part of Carbomer and 40-50 parts of purified water, mix to obtain aqueous mixture；
(2) oil mixture is slowly added into aqueous mixture at a temperature of 55-65 DEG C, the aqueous mixture keeps 500rpm
Stirring adds herb powder up to adding oil mixture, continues to stir 30 minutes, obtains medicinal mixture；
(3) medicinal mixture is cooled to 35-40 DEG C, homogeneous is carried out using high speed homogenization device, setting speed is 3000-
5000rpm, homogenizing time is 10-15 minutes, goes out container and is aged the traditional Chinese medicine emulsifiable paste that must be treated and sprain.
2. it is according to claim 1 to treat the preparation method of traditional Chinese medicine emulsifiable paste sprained, it is characterised in that the traditional Chinese medicine powder
End, oil mixture are mixed with water the weight part ratio of compound：10：13：42.
3. it is according to claim 1 to treat the preparation method of traditional Chinese medicine emulsifiable paste sprained, it is characterised in that the traditional Chinese medicine powder
End, oil mixture are mixed with water the weight part ratio of compound：14：28：52.
4. it is according to claim 1 to treat the preparation method of traditional Chinese medicine emulsifiable paste sprained, it is characterised in that the step (3)
Specially：Medicinal mixture is cooled to 35-40 DEG C, the P-hydroxybenzoic acid second of medicinal mixture quality 0.2-0.5% is added
Ester, homogeneous is carried out using high speed homogenization device, and setting speed is 3000rpm, and homogenizing time is 10-15 minutes, goes out container and is aged
The traditional Chinese medicine emulsifiable paste that treatment is sprained.
5. the traditional Chinese medicine emulsifiable paste that prepared by the preparation method of the traditional Chinese medicine emulsifiable paste that the treatment according to claim any one of 1-4 is sprained.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710300490.0A CN106924335A (en) | 2017-05-02 | 2017-05-02 | Traditional Chinese medicine emulsifiable paste that a kind for the treatment of is sprained and preparation method thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN117379513A (en) * | 2020-11-11 | 2024-01-12 | 浙江苏可安药业有限公司 | Chest-widening composition and application thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103142697A (en) * | 2013-03-01 | 2013-06-12 | 福建美菰林生物科技有限公司 | Pharmaceutical composition for relieving muscular soreness and preparation method thereof |
| CN103385914A (en) * | 2013-06-26 | 2013-11-13 | 山东无棣精盐厂 | Hot compress salt and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103142697A (en) * | 2013-03-01 | 2013-06-12 | 福建美菰林生物科技有限公司 | Pharmaceutical composition for relieving muscular soreness and preparation method thereof |
| CN103385914A (en) * | 2013-06-26 | 2013-11-13 | 山东无棣精盐厂 | Hot compress salt and preparation method thereof |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117379513A (en) * | 2020-11-11 | 2024-01-12 | 浙江苏可安药业有限公司 | Chest-widening composition and application thereof |
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