CN106913492A - A kind of antibacterial antioxidant composition of wormwood and its application in shampoo - Google Patents

A kind of antibacterial antioxidant composition of wormwood and its application in shampoo Download PDF

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Publication number
CN106913492A
CN106913492A CN201710295253.XA CN201710295253A CN106913492A CN 106913492 A CN106913492 A CN 106913492A CN 201710295253 A CN201710295253 A CN 201710295253A CN 106913492 A CN106913492 A CN 106913492A
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CN
China
Prior art keywords
wormwood
antioxidant composition
shampoo
leaf extract
antibacterial
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Pending
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CN201710295253.XA
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Chinese (zh)
Inventor
朱立华
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Individual
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Individual
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Priority to CN201710295253.XA priority Critical patent/CN106913492A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/46Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur
    • A61K8/463Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur containing sulfuric acid derivatives, e.g. sodium lauryl sulfate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • A61Q5/006Antidandruff preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • A61Q5/02Preparations for cleaning the hair
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00Preparations for affecting hair growth

Abstract

The invention discloses a kind of antibacterial antioxidant composition of wormwood and its application in shampoo, by weight, the antibacterial antioxidant composition of wormwood includes 14~18 parts of wormwood leaf extract, 3~5 parts of glutathione, 1~3 part of laruyl alcohol sodium sulfovinate.The wormwood shampoo being made up of the antibacterial antioxidant composition of the wormwood and laureth sodium sulfovinate, amphoteric surfactant and other conditioners etc., it is the Multifunctional shampoo of a natural environmental-protective, when hair scalp is cleaned, the problems such as hair being made to keep submissive, and can be prevented to a certain extent with treatment of dandruff, alopecia.

Description

A kind of antibacterial antioxidant composition of wormwood and its application in shampoo
Technical field
The present invention relates to daily necessities field, more particularly to a kind of antibacterial antioxidant composition of wormwood and its in shampoo Application.
Background technology
Through the ages, hair plays an important role in the instrument appearance of people, while being also the important of human health status Index.With the quickening pace of modern life, and environmental pollution is on the rise, the alopecia of modern is increasingly severe, work Pressure and the factors such as nervous and diet and communication, and the generation of alopecia symptom, or even part are increased from new field Young people are expanded to.Alopecia not only influences attractive in appearance, or even influences the psychological condition of people, and hair loss patient is caused to press at heart Power.At present, the bath preparation that natural plants make is small to skin excitant because of it, and maintenance effect is good, and has prevention or control Treat the special-effect of alopecia and extensively pursued.
Wormwood, perennial herb or slightly into suffruticose, plant has enhanced aroma.Stem list is given birth to or minority, brown or sallow Brown, base portion slightly lignifying, top Bi matter, and have a small number of short branches, leaf ground paper matter, above by canescence pubescence, base portion Generally without pseudostipule or minimum pseudostipule;Upper leaf partly splits with bract leaf pinniform, capitulum ellipse, corolla tubulose or height There is gland point pin cup-shaped, outside, and flower pesticide is narrow linear, and style and corolla be near isometric or slightly longer than corolla;Achene long avette or Long Circle, The flowering fruit bearing stage 9-10 months.Alias:Chinese mugwort, argy wormwood, family Chinese mugwort etc..All herbal medicine, have Wen Jing, dry, cold dispelling, hemostasis, anti-inflammatory, relieving asthma, only Cough, the effect such as antiabortive, antiallergy.Because of its special effect, can be used to make antibacterial, antiphlogistic medicament, there is promoting blood circulation qi-regulating, With " moxibustion disease of curing the disease, the non-small benefit of work(" Mei Zan.
At present, the shower preparation that most of natural plants are made, only meets basic cleaning, fragrant atmosphere effect and part soft Suitable, anti-dandruff function, can prevent simultaneously or treatment of dandruff is little with the special bath product of alopecia problem and effect is paid no attention to Think.And wormwood, as a kind of multi-functional Chinese medicine, fail to play its effect in shower preparation.
The content of the invention
It is described based on this, the invention reside in the defect for overcoming prior art, there is provided a kind of antibacterial antioxidant composition of wormwood The antibacterial antioxidant composition of wormwood prevents or treatment of dandruff and alopecia simultaneously while can meet skin cleaning, effectively Problem.The hair washing water energy being made based on the antibacterial antioxidant composition of this wormwood keeps hair while hair scalp is cleaned It is submissive, and the problems such as can prevent to a certain extent with treatment of dandruff, alopecia.
It is another object of the present invention to provide a kind of method for preparing the antibacterial antioxidant composition of the wormwood.
It is another object of the present invention to provide a kind of antibacterial anti-oxidant shampoo of wormwood.
Technical scheme is as follows:
A kind of antibacterial antioxidant composition of wormwood, by weight, comprising:
14~18 parts of wormwood leaf extract;
3~5 parts of glutathione;
1~3 part of laruyl alcohol sodium sulfovinate.
Glutathione is combined by glutamic acid, cysteine and glycine, and the tripeptides containing sulfydryl is turned into antioxygen With with integrate detoxication, be present in each cell of almost body, human free radical can not only be eliminated, people can also be improved Body immunity, safeguards health, anti-cell aging.All the time, the anti-oxidant of scalp gets the brush-off always, and studies hair Free radical that is existing, adhering on scalp and hair, can destroy cell tissue, if removed not in time, will result in the too early of scalp Aging, and hair unhealthy situation, with and come, the problems such as dandruff, alopecia will be produced.Inventor sends out through experiment Existing, when mixing by a certain percentage with wormwood leaf extract, laruyl alcohol sodium sulfovinate, with synergy, glutathione can increase Strong wormwood leaf extract, the cleaning of laruyl alcohol sodium sulfovinate, sterilized and antioxidant effect, and wormwood leaf extract and laruyl alcohol sulphur Acid esters sodium can promote absorption of the skin to glutathione, strengthen the antioxidant effect of glutathione, keep the health of skin of head. Based on the shampoo that the antibacterial antioxidant composition of wormwood of the present invention is made, hair can be made while hair scalp is cleaned The problems such as keeping submissive, and can prevent to a certain extent with treatment of dandruff, alopecia.
Preferably, the antibacterial antioxidant composition of the wormwood, by weight percentage, including:
16 parts of wormwood leaf extract;
4 parts of glutathione;
2 parts of laruyl alcohol sodium sulfovinate.
Research finds that when aforementioned proportion, synergy reaches most preferably the antibacterial antioxidant composition of wormwood.
Preferably, the wormwood leaf extract is the wormwood leaf extract in more than 3 years times.Research finds that 3 is more than the time Wormwood leaf extract, drug effect is gentle, is made skin care product, is easily absorbed by the skin, and the maintenance effect for skin compares 3 Wormwood leaf extract within time is more excellent, can more effectively prevent under the synergy with glutathione with hair growth, Dandruff problem.
The extracting method of the wormwood leaf extract is:Wormwood leaf powder is taken, 10ml volumes are added with 1g wormwood leaves powder Fraction is the ratio meter of 70% ethanol solution, heating and refluxing extraction 3 times after immersion 2h, and the time is respectively 2h, 1h, 0.5h, mistake Filter, filtrate concentration removes ethanol.By three extractions, the effective ingredient in wormwood leaf can be fully extracted, then by concentration Ethanol is reclaimed, brown ceramic powder wormwood leaf extract can be obtained after drying.Ethanol is reclaimed during concentration operation.Ended with this method gained Leaf extract, effective ingredient retains more complete, obvious in protection skin of head, the effect moistened on hair.
Further, the preparation method of the antibacterial antioxidant composition of the wormwood, comprises the following steps:
(1) glutathione, laruyl alcohol sodium sulfovinate are crushed into powdered component A;
(2) component A is mixed with wormwood leaf extract, is stirred, the antibacterial antioxidant composition of wormwood can be obtained.By paddy Guang Sweet peptide, laruyl alcohol sodium sulfovinate crush powdered little particle, contribute to being sufficiently mixed between wormwood leaf extract.
The invention also discloses a kind of wormwood shampoo, by weight, the wormwood shampoo includes:
The amphoteric surfactant is betaine type and/or oxidation amine amphoteric surfactant, described other conditionings Agent is comprising stabilizer, preservative, NMF, smooth dose, dispersant, thickener, the shampoo such as pigment often with conditioner Plant or several.The amphoteric surfactant can be specifically Cocoamidopropyl betaine, dodecyl dimethyl beet One or more in alkali, cocamidopropyl propyl amide amine oxide etc. of mixture.
Preferably, the amphoteric surfactant Cocoamidopropyl betaine.Through experimental study, using laureth Sodium sulfovinate under the booster action of amphoteric surfactant Cocoamidopropyl betaine, is cleaned as primary surfactant Effect is preferable, while Cocoamidopropyl betaine also plays foam enhancing, foam stabilizing and thickening.
Preferably, described smooth dose is dimethyl silicone polymer, and the preservative is DMDMH (1,3- bis- (hydroxyl Methyl) -5,5- methylimidazoles alkane -2,4- diketone).Dimethyl silicone polymer serves smooth, makes hair submissive;Preservative DMDMH plays antisepsis in wormwood shampoo, makes the wormwood shampoo storage more long.
Preferably, by weight, the wormwood shampoo includes:
Compared with prior art, the beneficial effects of the present invention are:The Chinese mugwort being made using the antibacterial antioxidant composition of wormwood Careless shampoo can effectively go elimination dandruff, prevention to be asked with hair growth while hair is cleaned with skin of head Topic.With low cost, cleaning effect is good, improves the function of hair hair quality and protection scalp.
Specific embodiment
To make the objects, technical solutions and advantages of the present invention become more apparent, with reference to embodiment, the present invention is made Further description, it should be appreciated that specific embodiment described herein is only used to explain the present invention, rather than limitation The scope of the present invention.
Embodiment 1~5
A kind of antibacterial antioxidant composition of wormwood, each component weight portion that the antibacterial antioxidant composition of wormwood is included Number such as table 1:
Table 1
It is the wormwood leaf extract of 3 years in the time that the wormwood leaf extract is.Extracting method is:Wormwood leaf powder is taken, with 1g wormwood leaves powder adds the ratio meter of the ethanol solution that 10ml volume fractions are 70%, heating and refluxing extraction 3 times after immersion 2h, Time is respectively 2h, 1h, 0.5h, filtering, and filtrate concentration removes ethanol.The preparation side of the antibacterial antioxidant composition of wormwood Method, comprises the following steps:(1) glutathione, laruyl alcohol sodium sulfovinate are crushed into powdered component A;(2) by component A mixes with wormwood leaf extract, stirs, and can obtain the antibacterial antioxidant composition of wormwood.
Embodiment 6
A kind of antibacterial antioxidant composition of wormwood, the antibacterial antioxidant composition each component parts by weight of wormwood, wormwood The extracting method of leaf extract is same as Example 1, and difference is that it is 2 years in the time that wormwood leaf extract described in the present embodiment is Wormwood leaf extract.
Embodiment 7
A kind of antibacterial antioxidant composition of wormwood, the antibacterial antioxidant composition each component parts by weight of wormwood, wormwood The extracting method of leaf extract is same as Example 1, and difference is that it is 5 years in the time that wormwood leaf extract described in the present embodiment is Wormwood leaf extract.
The wormwood shampoo of embodiment 8~14
Table two
Embodiment 15
A kind of wormwood shampoo, each component parts by weight are same as Example 8 in the wormwood shampoo, and difference is, this The antibacterial antioxidant composition of wormwood used is the antibacterial antioxidant composition of gained wormwood of embodiment 2 in embodiment.
Embodiment 16
A kind of wormwood shampoo, each component parts by weight are same as Example 8 in the wormwood shampoo, and difference is, this The antibacterial antioxidant composition of wormwood used is that the antibacterial antioxidant composition of gained wormwood of embodiment 3 is identical in embodiment.
Embodiment 17
A kind of wormwood shampoo, each component parts by weight are same as Example 8 in the wormwood shampoo, and difference is, this The antibacterial antioxidant composition of wormwood is that the antibacterial antioxidant composition of gained wormwood of embodiment 6 is identical used in embodiment.
Embodiment 18
A kind of wormwood shampoo, each component parts by weight are same as Example 8 in the wormwood shampoo, and difference is, this The antibacterial antioxidant composition of wormwood is that the antibacterial antioxidant composition of gained wormwood of embodiment 7 is identical used in embodiment.
Comparative example 1
A kind of wormwood shampoo, each component parts by weight are same as Example 8 in the wormwood shampoo, and difference is, this Replace the antibacterial antioxidant composition of wormwood using laruyl alcohol sodium sulfovinate in embodiment.
Obtained embodiment 8~18 and comparative example 1 are carried out into skin effect test.
Choose 120 and suffer within 20 years old~60 years old alopecia, the different age group of many dandruff symptoms as subjects, be divided into 12 groups, every group of 10 people test embodiment 8~18 with comparative example 1 respectively, to each project after everyone uses 15 days Scored, highest is divided into 10 points, minimum to be divided into 0 point, makes even respectively.8~10 points, represent that effect is very good;5~8 points, represent Effect can receive;3~5 points, represent no effect;0~3 point, indicate counter productive.
The combination property of table three is evaluated and tested
From table 3 it is observed that the present invention is for slight alopecia, many dandruff symptoms, can effectively improve and treat, have There is prominent progress with significant effect;The antibacterial antioxidant composition number of wormwood is more, then effect is better, and 3 times of use, The embodiment 8 of 5 time wormwood extracts, embodiment 18 are more excellent than the effect of embodiment 17 using 2 time wormwood extracts.
Embodiment described above only expresses several embodiments of the invention, and its description is more specific and detailed, but simultaneously Can not therefore be construed as limiting the scope of the patent, the protection domain of patent of the present invention should be with appended claims It is accurate.

Claims (9)

1. the antibacterial antioxidant composition of a kind of wormwood, it is characterised in that by weight, the antibacterial antioxidant composition of wormwood Comprising:
14~18 parts of wormwood leaf extract;
3~5 parts of glutathione;
1~3 part of laruyl alcohol sodium sulfovinate.
2. the antibacterial antioxidant composition of wormwood according to claim 1, it is characterised in that by weight, the wormwood suppression Bacterium antioxidant composition includes:
16 parts of wormwood leaf extract;
4 parts of glutathione;
2 parts of laruyl alcohol sodium sulfovinate.
3. the antibacterial antioxidant composition of wormwood according to claim 2, it is characterised in that the wormwood leaf extract is 3 years The wormwood leaf extract in above time.
4. the antibacterial antioxidant composition of wormwood according to claim 3, it is characterised in that the extraction of the wormwood leaf extract Method is:Wormwood leaf powder is taken, it is leaching in terms of 70% ratio of ethanol solution to add 10ml volume fractions by 1g wormwood leaves powder Heating and refluxing extraction 3 times after bubble 2h, the time is respectively 2h, 1h, 0.5h, filtering, and filtrate concentration removes ethanol.
5. according to any claim of claim 1 or 2 the antibacterial antioxidant composition of wormwood preparation method, its feature exists In comprising the following steps:
(1) glutathione, laruyl alcohol sodium sulfovinate are crushed into powdered component A;
(2) component A is mixed with wormwood leaf extract, is stirred, obtain the antibacterial antioxidant composition of wormwood.
6. a kind of wormwood shampoo, it is characterised in that by weight, the wormwood shampoo includes:
The amphoteric surfactant is betaine type and/or oxidation amine amphoteric surfactant, described other conditioner bags Containing stabilizer, preservative, NMF, smooth dose, dispersant, thickener, the shampoo such as pigment often with the one kind in conditioner or It is several.
7. wormwood shampoo according to claim 6, it is characterised in that the amphoteric surfactant cocamidopropyl propyl amide is sweet Dish alkali.
8. wormwood shampoo according to claim 6, it is characterised in that described smooth dose is dimethyl silicone polymer, described Preservative is DMDMH.
9. wormwood shampoo according to claim 6, it is characterised in that by weight, the wormwood shampoo includes:
CN201710295253.XA 2017-04-28 2017-04-28 A kind of antibacterial antioxidant composition of wormwood and its application in shampoo Pending CN106913492A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108553367A (en) * 2018-06-04 2018-09-21 刘朝延 A kind of wormwood shampoo and preparation method thereof
CN109662923A (en) * 2019-01-08 2019-04-23 百草堂医药股份有限公司 A kind of wormwood anticreep leaves shampoo and preparation method thereof
CN115813833A (en) * 2023-02-15 2023-03-21 江西中医药大学 Bacteriostatic anti-inflammatory hair-growing essence and preparation method thereof

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CN105168074A (en) * 2015-07-15 2015-12-23 碌柚葉(香港)有限公司 Antidandruff and antipruritic traditional Chinese medicine composition and application and preparation method thereof
CN106075390A (en) * 2016-07-28 2016-11-09 广东药科大学 A kind of positively charged anticreep composite and flexible liposome and preparation method thereof

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Publication number Priority date Publication date Assignee Title
CN105168074A (en) * 2015-07-15 2015-12-23 碌柚葉(香港)有限公司 Antidandruff and antipruritic traditional Chinese medicine composition and application and preparation method thereof
CN106075390A (en) * 2016-07-28 2016-11-09 广东药科大学 A kind of positively charged anticreep composite and flexible liposome and preparation method thereof

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108553367A (en) * 2018-06-04 2018-09-21 刘朝延 A kind of wormwood shampoo and preparation method thereof
CN109662923A (en) * 2019-01-08 2019-04-23 百草堂医药股份有限公司 A kind of wormwood anticreep leaves shampoo and preparation method thereof
CN115813833A (en) * 2023-02-15 2023-03-21 江西中医药大学 Bacteriostatic anti-inflammatory hair-growing essence and preparation method thereof
CN115813833B (en) * 2023-02-15 2023-11-21 江西中医药大学 Antibacterial anti-inflammatory hair-growing essence and preparation method thereof

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