CN106912942A - Lutein purple perilla method for producing soft capsule - Google Patents
Lutein purple perilla method for producing soft capsule Download PDFInfo
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- CN106912942A CN106912942A CN201710157887.9A CN201710157887A CN106912942A CN 106912942 A CN106912942 A CN 106912942A CN 201710157887 A CN201710157887 A CN 201710157887A CN 106912942 A CN106912942 A CN 106912942A
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- parts
- lutein
- soft capsule
- purple perilla
- glue
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- 239000001656 lutein Substances 0.000 title claims abstract description 65
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- 229960005375 lutein Drugs 0.000 title claims abstract description 65
- ORAKUVXRZWMARG-WZLJTJAWSA-N lutein Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CCCC1(C)C)C=CC=C(/C)C=CC2C(=CC(O)CC2(C)C)C ORAKUVXRZWMARG-WZLJTJAWSA-N 0.000 title claims abstract description 65
- KBPHJBAIARWVSC-XQIHNALSSA-N trans-lutein Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CC(O)CC1(C)C)C=CC=C(/C)C=CC2C(=CC(O)CC2(C)C)C KBPHJBAIARWVSC-XQIHNALSSA-N 0.000 title claims abstract description 65
- FJHBOVDFOQMZRV-XQIHNALSSA-N xanthophyll Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CC(O)CC1(C)C)C=CC=C(/C)C=CC2C=C(C)C(O)CC2(C)C FJHBOVDFOQMZRV-XQIHNALSSA-N 0.000 title claims abstract description 65
- 239000007901 soft capsule Substances 0.000 title claims abstract description 64
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Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23D—EDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS, COOKING OILS
- A23D9/00—Other edible oils or fats, e.g. shortenings, cooking oils
- A23D9/007—Other edible oils or fats, e.g. shortenings, cooking oils characterised by ingredients other than fatty acid triglycerides
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Medicines Containing Plant Substances (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
A kind of lutein purple perilla method for producing soft capsule.Easily there is oxidative degradation in traditional lutein extracting method.A kind of lutein purple perilla method for producing soft capsule, its composition includes：Soft capsule skin is constituted and content composition, described soft capsule skin composition includes gelatin, glycerine, purified water and burnt sugar coloring, described content composition includes Bilberry fruit P.E, grape seed extract, lutein, bata-carotene, Purple Perilla Seed Oil and beeswax, it is characterized in that：The parts by weight of its each composition are：470 parts of 15 parts of Bilberry fruit P.E, 100 parts of grape seed extract, 15 parts of lutein, 1.5 parts of bata-carotene, 318.5 parts of Purple Perilla Seed Oil, 15 parts of beeswax, 235 parts of gelatin, 117 parts of glycerine, 11.2 parts of burnt sugar coloring and purified water.The present application relates to field of health care food, lutein purple perilla method for producing soft capsule is more particularly to applied to.
Description
Technical field：
The present application relates to a kind of field of health care food, more particularly to a kind of lutein purple perilla method for producing soft capsule.
Background technology：
Lutein also known as " Lutein ", lutein belong to " carotenoid " class material, and it is to constitute corn, vegetables, water
Really, the important component of the phytochrome such as flowers, is widely present in spinach, wild cabbage, peach, mango, pawpaw, banana, potato, chrysanthemum
In the plants such as flower, pot marigold, wherein content is higher in marigold, is the primary raw material source that current lutein is extracted；Lutein
Molecular formula be C40H56O2, molecular weight is 568.85.Free lutein is all extremely unstable to heat, light and oxygen；Traditional leaf is yellow
Plain extracting method mainly has organic solvent extraction, microwave heating method and supercritical carbon dioxide extraction method.Organic solvent is extracted
Extraction efficiency is low, extraction time is long, and due to free lutein less stable, extraction time is long to make chromophyll easily send out
Raw oxidative degradation.
The content of the invention：
It is an object of the invention to provide a kind of lutein purple perilla method for producing soft capsule, help people's raising immune to reach
Power, the effect of anti-aging.
Above-mentioned purpose is realized by following technical scheme：
A kind of lutein purple perilla soft capsule, its composition includes：Soft capsule skin is constituted and content composition, described soft capsule skin group
Into including gelatin, glycerine, purified water and burnt sugar coloring, described content composition includes Bilberry fruit P.E, grape seed extract, leaf
Flavine, beta carotene, Purple Perilla Seed Oil and beeswax, the parts by weight of its each composition are：Bilberry fruit P.E 1-4 parts, grape pip extraction
Thing 100-120 parts, lutein 15-18 parts, beta carotene 1-3 parts, Purple Perilla Seed Oil 300-350 parts, beeswax 10-18 parts, gelatin
200-250 parts, glycerine 110-125 parts, burnt sugar coloring 10-25 parts and purified water 450-500 parts.
Described lutein purple perilla soft capsule, described content composition includes：15 parts of Bilberry fruit P.E, grape pip are extracted
100 parts of thing, 15 parts of lutein, 1.5 parts of beta carotene, 318.5 parts of Purple Perilla Seed Oil, 15 parts of beeswax, 235 parts of gelatin, glycerine 117
470 parts of part, 11.2 parts of burnt sugar coloring and purified water.
It is prepared by described lutein purple perilla method for producing soft capsule, raw material；Glue is prepared；Feed liquid dispensing；Pelleting；Sizing；
Dry, described feed liquid blending process is：Take recipe quantity beeswax, Purple Perilla Seed Oil to be placed in preparing tank, be heated to 65 ± 2 DEG C, stir
Mixing makes beeswax melt completely, is well mixed, and obtains oily wax liquor；Then 40 DEG C are cooled to；Bulk drug is added, is stirred, in vacuum
Stirred 15-30 minutes in mulser, vacuumized, make its vacuum up to -0.05MPa~-0.08MPa, stirred 20 minutes to feed liquid
Bubble-free, obtains feed liquid.
Described lutein purple perilla method for producing soft capsule, the preparation process of described bulk drug is：By Bilberry fruit P.E
Powder, grape seed extract powder, lutein powder, beta carotene powder, Purple Perilla Seed Oil, cross 100 mesh sieves, are weighed by recipe quantity.
Described lutein purple perilla method for producing soft capsule, described glue process for preparation is：Take the glycerine of recipe quantity, pure
Change water being placed in glue tank, after being heated to 60-80 DEG C, add the gelatin of recipe quantity, stirring to gelatin is all dissolved, vacuumized, makes
Its vacuum reaches -0.08Mpa, and glue is crossed 100 mesh sieves in 30 minutes by stirring to glue bubble-free, in standing, glue in glue-storing barrel
55 DEG C -60 DEG C of insulation.
Described lutein purple perilla method for producing soft capsule, described pelleting process is：Glue, feed liquid are transferred to soft capsule
Pellet processing machine carries out compacting pelletization, and it is 0.5g to control every loading amount of capsule 's content.
The type-approval process of the step of described lutein purple perilla method for producing soft capsule, described production method is：Will pressure
Good soft capsule is placed in rotating cage, is shaped under conditions of 30-40%, 18-26 DEG C of temperature about 1.5-2.0 in relative humidity
Hour.
Described lutein purple perilla method for producing soft capsule, described drying process is：Obtained soft capsule is uniform
It is laid in basin, in relative humidity, drying is qualified to moisture content under conditions of 20-30%, 15-25 DEG C of temperature.
Beneficial effects of the present invention：
1. lutein purple perilla soft capsule of the invention, it is primary raw material to use lutein, and lutein is present in various plants,
Shielded in the photosynthesis of plant, early in last century the mid-80, western medicine researcher finds that plant institute
The natural carotenol for containing is a kind of antioxidant of excellent performance；Massive epidemiology evidence shows, the addition of lutein and with
The synergy of other compositions so that the present invention has protective effect to vision, and with prevention, artery sclerosis, enhancing
The effects such as immunity, especially in prevention canceration generation, the aspects such as cancer development are delayed to play an important role, a certain amount of leaf is yellow
Element is added in food, a series of diseases that can prevent human body from causing by organ senescence.
Lutein purple perilla soft capsule of the invention, adds Purple Perilla Seed Oil, with the synergy of other compositions under to reduce
Cholesterol, reduction blood fat, atherosclerosis, reduction cerebral thrombus and angiocardiopathy have persistently positive effective
Effect；The olefin(e) acid of 20 carbon 5 (EPA) and 20 can be changed into human body in the presence of enzyme after alpha-linolenic acid intake human body
The olefin(e) acid of two carbon 6 (DHA), it is exactly the Main Ingredients and Appearance of deep sea fish oil, therefore is called plant deep sea fish oil, more more preferable than deep sea fish oil
It is that it is free of cholesterol, EPA and DHA has reducing blood lipid and improves the effect of memory；Alpha-linolenic acid also has antiallergy and inverse
Adaptability is improved in border and suppress the effect of some cancer cells.It can not independently synthesize in human body, need to be by food supply.
Lutein purple perilla soft capsule of the invention, the Grape Seed Extract Procyanidin (OPC) of addition is a kind of efficient
Free radical scavenger；As the present invention under synergy the oxidative function of its Green Tea Extract be ascorbic 20 times, vitamin
50 times of E；Free radical poisonous in human body can be removed, protection human cell tissue exempts from, by the oxidative damage of free radical, to prevent
The kind more than 80 such as quick, cancer, aging disease relevant with free radical, reduces cholesterol and improves HDL to low-density
The ratio of lipoprotein, is all the method for most important prevention of cardiovascular disease, and grape pip effect is that in reducing blood
Low density cholesterol, while the level of HDL-C can be improved, both take into account, and in addition, grape seed extract contains
Abundant vitamin E, vitamin E is famous antioxidant, so the effect of grape pip also includes the various diseases of prevention, while
Skin and muscle is kept fit state, grape pip effect also has anti-prostate tumor and anti-liver neoplasm etc., grape-kernel oil by
Grape seed is colded pressing and is made, due to the vegetalitas Omega-3 that cannot be voluntarily manufactured rich in human body（Leukotrienes）And unsaturated fat
Acid, is accordingly regarded as a kind of edible health-care oil, removes free radical, anti-aging, strengthen immunity, antiallergy, protection blood vessel, anti-spoke
Penetrate, protect eyes, prevention, the retinitis.
Lutein purple perilla soft capsule of the invention, the Bilberry fruit P.E for being used, with illness in eye blood circulation is improved, suppresses
Eliminate eye paathogenic factor, there is provided nutrition needed for eye, safeguard the effect of eye capilary health.In Purple Perilla Seed Oil mixed process
Heating-up temperature is 65 ± 2 DEG C, and stirring makes beeswax melt completely, is well mixed, the biological effective components preservation of the oily wax liquor for obtaining
Preferably oily wax liquor；Then 40 DEG C are cooled to；Glue is added, is stirred, stirred 15-30 minutes in vacuum emulsifying machine, obtained
The best product of invention effect.
Lutein purple perilla soft capsule of the invention, adds β-carrotene (C40H56) it is one of carotenoid, be also
Crocus fat-soluble compound, it is that most generally existing is also most stable of natural pigment in nature；In many natural foods
For example：Green vegetables, sweet potato, carrot, spinach, pawpaw, mango etc., all have abundant β-carrotene, and β-carrotene is
A kind of antioxidant, is to safeguard the indispensable nutrient of health after being added in this product with detoxication,
Anticancer, prevention of cardiovascular disease, cataract and it is anti-oxidant on have a significant function, and and then prevent what aging and aging from causing
Various degenerative disorders.
Verification method is：（1）Choice experiment materials and methods：Including：（a）The selection of tested material, the tested material and comfort
Agent is soft capsule, and outward appearance is essentially identical, and tested material content is Bilberry fruit P.E, grape seed extract, lutein, β-Hu Luo
Bu Su and Purple Perilla Seed Oil etc., every 0.5g, adult are recommended as twice daily, and two every time, the tested material is commented through safety toxicology
Valency is defined as safe product, and tested material meets the pertinent regulations of country with the Hygienic Index of placebo；（b）Subject is basic
Situation and exclusion standard, it is 10~50 years old to select the age in the personnel for participating in experiment from entering one's name voluntarily, and for a long time with eye, eyesight is easily tired
Labor person is subject 120, wherein test group, each 60 of control group, tests male 31, women 29,10~50 years old age,
Average age（30±1）Year；Control group male 28, women 32,12~50 years old age, average age（31±1）It is year, tested
Person's exclusion standard reference《Health food is checked and assessment technique specification》（2003 editions）Part II " function assessment evaluation test side
The 2nd article of Part VI in method "；（c）The design of experiment and packet, using itself and between group two kinds of control designs, according to symptom
And eye test situation, while considering the factors such as age, sex, test group and control group, each group of people are divided into by random, double-blind study
Several 60 people；（d）The method of test-meal, test group takes tested material by recommendation method and recommended amounts, and 2 times a day, 2 every time；Control
Group takes placebo, usage and the same test group of consumption, continuously takes 30d；（e）The index of observation, observation index is divided into security
Index and efficiency index, indices in test-meal on-test and at the end of it is each determine once, specific observation index reference《Protect
Health food is checked and assessment technique specification》（Version in 2003）In Part VI in Part II " function assessment evaluation test method "
The 5th article；（f）Efficiency index criterion, be divided into symptom improve, it is effective, invalid.Symptom improves：Ophthalmodynia, eye are swollen, photophobia,
The dry and astringent any symptom of blurred vision, eye improves 1 point and more than 1 point and is and improves, and 5 kinds of symptoms are any to be improved and other symptoms are without evil
Change and judge symptom improvement；Effectively：Symptom improves and difference >=0.1 before and after duration of photopic vision, and has system through statistical comparison difference
Meter learns meaning；It is invalid：Not up to effective standard；（g）The treatment of final data, the data inputting database that experimental period is collected,
It is analyzed and statistical procedures, symptom integral and duration of photopic vision are measurement data, and improvement rate volume total effective rate is provided to count
Material, is respectively adopted t inspections and x2 inspections are compared；（2）The analysis method of experimental result：（a）Ordinary circumstance before two groups of test-meals
Comparing, age, sex, duration of photopic vision, left and right far visual acuity, symptom integral indices difference are without system before two groups of test-meals
Meter learns meaning（P>0.05）, with comparativity；（b）The observation of safety indexes, test-meal before and after test group and control group crowd's
General physical examination, blood parameters and routine urianlysis result are in normal range (NR), test group and control before test-meal
Group crowd Chest X-rays, electrocardiogram, Abdominal B type ultrasonography are checked in normal range (NR)；（c）The comparing improved to distant vision, is shown in accompanying drawing 1；（d）It is right
The comparing of duration of photopic vision change, test group duration of photopic vision risen to by 0.68 ± 0.17 before test-meal after test-meal 0.81 ±
0.15 improves 0.13 ± 0.14, and difference has statistical significance（P<0.01）;Test group duration of photopic vision after test-meal（0.78±
0.18）With control group（0.68±0.10）Comparing difference is statistically significant（P<0.01）；（e）The comparing that ill symptomses improve,
See accompanying drawing 2；（f）Ill symptomses integrate statistical comparison, the eye symptom integration of test group by take before tested material 3.98 ±
1.88 be reduced to after taking 2.23 ± 1.69 before and after comparing difference it is statistically significant（P<0.01）;After test-meal test group with it is right
According to group（3.36±1.88）Compare, difference is statistically significant（P<0.01）；（g）The comparing of total effective rate before and after test-meal, experiment
The total effectively number of cases of group is 32, and total effective rate is 53.56%；The total effectively number of cases of control group is 2, and total effective rate is 2.56%；Two
Group total effective rate compares, and difference is statistically significant（P<0.01）.
Brief description of the drawings：
Fig. 1 is influence of the lutein purple perilla soft capsule of the invention to subject's distant vision（n=60）.
Fig. 2 is influence of the lutein purple perilla soft capsule of the invention to subject's eye symptom.
Fig. 3 is lutein purple perilla soft capsule production technology sketch of the invention.
Specific embodiment：
Embodiment 1：
Lutein purple perilla soft capsule, its composition includes：Soft capsule skin is constituted and content composition, described soft capsule skin composition bag
Gelatin, glycerine, purified water and burnt sugar coloring are included, described content composition includes that Bilberry fruit P.E, grape seed extract, leaf are yellow
Element, beta carotene, Purple Perilla Seed Oil and beeswax, the parts by weight of its each composition are：Bilberry fruit P.E 1-4 parts, grape seed extract
100-120 parts, lutein 15-18 parts, beta carotene 1-3 parts, Purple Perilla Seed Oil 300-350 parts, beeswax 10-18 parts, gelatin 200-
250 parts, glycerine 110-125 parts, burnt sugar coloring 10-25 parts and purified water 450-500 parts.
Embodiment 2
A kind of lutein purple perilla soft capsule, its composition includes：Soft capsule skin is constituted and content composition, described soft capsule skin group
Into including gelatin, glycerine, purified water and burnt sugar coloring, described content composition includes Bilberry fruit P.E, grape seed extract, leaf
Flavine, beta carotene, Purple Perilla Seed Oil and beeswax, the parts by weight of its each composition are：15 parts of Bilberry fruit P.E, grape pip are extracted
100 parts of thing, 15 parts of lutein, 1.5 parts of beta carotene, 318.5 parts of Purple Perilla Seed Oil, 15 parts of beeswax, 235 parts of gelatin, glycerine 117
470 parts of part, 11.2 parts of burnt sugar coloring and purified water.
Embodiment 3：
The step of lutein purple perilla method for producing soft capsule according to embodiment 1, described production method is：（1）Raw material
Prepare；（2）Glue is prepared；（3）Feed liquid dispensing；（4）Pelleting；（5）Sizing；（6）Dry；（7）Select ball；（8）Pack and check, enter
Storehouse.Described feed liquid blending process is：In the workshop that purification of air rank is 100,000 grades, the free of contamination feelings of pilot process are ensured
Under condition, take recipe quantity beeswax, Purple Perilla Seed Oil and be placed in preparing tank, be heated to 65 ± 2 DEG C, stirring makes beeswax melt completely, mixes
Uniformly, oily wax liquor is obtained；Then 40 DEG C are cooled to；Bulk drug is added, is stirred, stirred 15-30 minutes in vacuum emulsifying machine,
Vacuumize, make its vacuum up to -0.05MPa~-0.08MPa, stirring obtains feed liquid in 20 minutes to feed liquid bubble-free, standby.
Embodiment 4：
The bulk drug of the step of lutein purple perilla method for producing soft capsule according to embodiment 3, described production method
Preparation process is：In the workshop that purification of air rank is 100,000 grades, in the case of ensureing that pilot process is free of contamination, cowberry is carried
Thing powder, grape seed extract powder, lutein powder, beta carotene powder, Purple Perilla Seed Oil are taken, 100 mesh sieves are crossed, weighed by recipe quantity, it is standby
With.
Embodiment 5：
The glue of the step of lutein purple perilla method for producing soft capsule according to embodiment 3 or 4, described production method is matched somebody with somebody
Process processed is：In the workshop that purification of air rank is 100,000 grades, in the case of ensureing that pilot process is free of contamination, recipe quantity is taken
Glycerine, purified water being placed in glue tank, after being heated to 60-80 DEG C, add the gelatin of recipe quantity, and stirring to gelatin is all dissolved, taken out
Vacuum, makes its vacuum up to -0.08Mpa, and glue is crossed 100 mesh sieves, in quiet in glue-storing barrel in 30 minutes by stirring to glue bubble-free
Put, glue is incubated 55 DEG C -60 DEG C, used as soft capsule skin raw material.
Embodiment 6：
The pressure of the step of lutein purple perilla method for producing soft capsule according to embodiment 3 or 4 or 5, described production method
Ball process is：In the workshop that purification of air rank is 100,000 grades, in the case of ensureing that pilot process is free of contamination, by glue, material
Liquid is transferred to soft capsule pellet processing machine and carries out compacting pelletization, and it is 0.5g to control every loading amount of capsule 's content.
Embodiment 7：
The step of lutein purple perilla method for producing soft capsule according to embodiment 3 or 4 or 5 or 6, described production method
Type-approval process is：In the workshop that purification of air rank is 100,000 grades, in the case of ensureing that pilot process is free of contamination, by what is pressed
Soft capsule is placed in rotating cage, is shaped under conditions of 30-40%, 18-26 DEG C of temperature about 1.5-2.0 hours in relative humidity.
Embodiment 8：
Lutein purple perilla method for producing soft capsule according to embodiment 3 or 4 or 5 or 6 or 7, the step of described production method
Rapid drying process is：In the workshop that purification of air rank is 100,000 grades, in the case of ensureing that pilot process is free of contamination, will make
The soft capsule for obtaining uniformly is laid in basin, is dried 24 hours under conditions of 20-30%, 15-25 DEG C of temperature in relative humidity
It is qualified with up to moisture content.
Embodiment 9：
Lutein purple perilla method for producing soft capsule according to embodiment 3 or 4 or 5 or 6 or 7 or 8, described production method
The ball process of selecting of step is：In the workshop that purification of air rank is 100,000 grades, in the case of ensureing that pilot process is free of contamination, will
Dried soft capsule is placed on lamp inspection desk rejects the underproof soft capsules such as special-shaped ball, big piller, bubble ball, oil leak ball.
Packaging and inspection, storage process are：In the workshop that purification of air rank is 100,000 grades, ensure pilot process without dirt
In the case of dye, dress is wrapped inside first, packed with the medicinal polyester bottles of oral administration solid, 60 every bottle；Then outsourcing is carried out
Dress, by intermediate products to be packaged → put specification → fill big case → loading packing slip → joint sealing → label；Finally check, enter
Storehouse, the finished product that will have been packed, randomly selects product, is tested according to the method described in quality standard and requirement, and it is qualified to check
Afterwards, finished product storage.
Embodiment 10：
Lutein purple perilla method for producing soft capsule described in a kind of utilization embodiment 1 to 9, before formal production, using a series of
Method be used for effect and verified, its experimental procedure is：（1）Choice experiment materials and methods：Including：（a）Tested material
Selection；（b）Subject's basic condition and exclusion standard；（c）The design of experiment and packet；（d）The method of test-meal；（e）Observation
Index；（f）Efficiency index criterion；（g）The treatment of final data；（2）The analysis method of experimental result：（a）Two groups
The comparing of ordinary circumstance before test-meal；（b）The observation of safety indexes；（c）The comparing improved to distant vision；（d）It is lasting to photopic vision
Spend the comparing of change；（e）The comparing that ill symptomses improve；（f）Ill symptomses integrate statistical comparison；（g）It is total effective before and after test-meal
The comparing of rate.
Claims (8)
1. a kind of lutein purple perilla soft capsule, its composition includes：Soft capsule skin is constituted and content composition, described soft capsule skin
Composition includes gelatin, glycerine, purified water and burnt sugar coloring, described content constitute include Bilberry fruit P.E, grape seed extract,
Lutein, beta carotene, Purple Perilla Seed Oil and beeswax, it is characterized in that：The parts by weight of its each composition are：Bilberry fruit P.E 1-4
Part, grape seed extract 100-120 parts, lutein 15-18 parts, beta carotene 1-3 parts, Purple Perilla Seed Oil 300-350 parts, beeswax
10-18 parts, gelatin 200-250 parts, glycerine 110-125 parts, burnt sugar coloring 10-25 parts and purified water 450-500 parts.
2. lutein purple perilla soft capsule according to claim 1, it is characterized in that：Described content composition includes：Cowberry
15 parts of extract, 100 parts of grape seed extract, 15 parts of lutein, 1.5 parts of beta carotene, 318.5 parts of Purple Perilla Seed Oil, beeswax 15
Part, 235 parts of gelatin, 117 parts of glycerine, 11.2 parts of burnt sugar coloring and 470 parts of purified water.
3. it is prepared by a kind of described lutein purple perilla method for producing soft capsule of one of claim 1 or 2, raw material；Glue is prepared；Material
Liquid dispensing；Pelleting；Sizing；Dry, it is characterized in that：Described feed liquid blending process is：Recipe quantity beeswax, Purple Perilla Seed Oil is taken to be placed in
In preparing tank, 65 ± 2 DEG C are heated to, stirring makes beeswax melt completely, is well mixed, and obtains oily wax liquor；Then 40 DEG C are cooled to；Plus
Enter bulk drug, stir, in vacuum emulsifying machine stir 15-30 minute, vacuumize, make its vacuum reach -0.05MPa~-
0.08MPa, stirring obtains feed liquid in 20 minutes to feed liquid bubble-free.
4. lutein purple perilla method for producing soft capsule according to claim 3, it is characterized in that：The preparation of described bulk drug
Process is：By Bilberry fruit P.E powder, grape seed extract powder, lutein powder, beta carotene powder, Purple Perilla Seed Oil, 100 mesh sieves are crossed,
Weighed by recipe quantity.
5. the lutein purple perilla method for producing soft capsule according to claim 3 or 4, it is characterized in that：Described glue is prepared
Process is：Glycerine, purified water the being placed in glue tank of recipe quantity are taken, after being heated to 60-80 DEG C, the gelatin of recipe quantity, stirring is added
All dissolved to gelatin, vacuumized, make its vacuum up to -0.08Mpa, glue is crossed 100 in 30 minutes by stirring to glue bubble-free
Mesh sieve, in being stood in glue-storing barrel, glue is incubated 55 DEG C -60 DEG C.
6. the lutein purple perilla method for producing soft capsule according to claim 3 or 4 or 5, it is characterized in that：Described pelleting mistake
Cheng Wei：Glue, feed liquid are transferred into soft capsule pellet processing machine carries out compacting pelletization, and it is 0.5g to control every loading amount of capsule 's content.
7. the lutein purple perilla method for producing soft capsule according to claim 3 or 4 or 5 or 6, it is characterized in that：Described life
The type-approval process of the step of product method is：The soft capsule that will be pressed is placed in rotating cage, in relative humidity in 30-40%, temperature 18-
Shaped under conditions of 26 DEG C about 1.5-2.0 hours.
8. the lutein purple perilla method for producing soft capsule according to claim 3 or 4 or 5 or 6 or 7, it is characterized in that：Described
Drying process is：Obtained soft capsule is uniformly laid in basin, in relative humidity in 20-30%, 15-25 DEG C of temperature
Under the conditions of drying it is qualified to moisture content.
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| CN201710157887.9A CN106912942A (en) | 2017-03-16 | 2017-03-16 | Lutein purple perilla method for producing soft capsule |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110720513A (en) * | 2019-11-21 | 2020-01-24 | 重庆市科学技术研究院 | Perilla yogurt for improving visual function and preparation method thereof |
| CN113796479A (en) * | 2021-08-24 | 2021-12-17 | 云南省工业大麻产业投资有限公司 | Eye-protecting beverage formula and processing method |
| CN113796532A (en) * | 2021-08-24 | 2021-12-17 | 云南省工业大麻产业投资有限公司 | Formula and processing method of lutein eye-protecting soft capsule |
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| CN110720513A (en) * | 2019-11-21 | 2020-01-24 | 重庆市科学技术研究院 | Perilla yogurt for improving visual function and preparation method thereof |
| CN113796479A (en) * | 2021-08-24 | 2021-12-17 | 云南省工业大麻产业投资有限公司 | Eye-protecting beverage formula and processing method |
| CN113796532A (en) * | 2021-08-24 | 2021-12-17 | 云南省工业大麻产业投资有限公司 | Formula and processing method of lutein eye-protecting soft capsule |
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