CN106902211A - One kind scalds medicament and preparation method thereof - Google Patents
One kind scalds medicament and preparation method thereof Download PDFInfo
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- CN106902211A CN106902211A CN201710325010.6A CN201710325010A CN106902211A CN 106902211 A CN106902211 A CN 106902211A CN 201710325010 A CN201710325010 A CN 201710325010A CN 106902211 A CN106902211 A CN 106902211A
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Abstract
One kind scalds medicament and preparation method thereof, is related to medicament for treating scald technical field.One kind is scalded medicament and is prepared by the following method：The first mixture is obtained after the honeysuckle of 10~15 parts in parts by weight, 7~12 parts of Cornu Bubali powder, 2~5 parts of the root of Dahurain angelica, 1~3 part of rhizoma atractylodis, 2~5 parts of the coptis and 1~5 part of dragon's blood are cleaned, clean, crush and mixed successively；Can effectively be played by the drug effect of the Chinese medicine after crushing.After first mixture to be added 20~25 parts of alcohol the first filtrate is filtrated to get after 30~45min of heating at 95~98 DEG C；By 30~45 parts of honey and 0.1~0.3 part of borneol in the first dissolved in filtrate.This scalds medicament to no skin irritation, and treatment burn and scald has the advantages that healing is fast, scar is light, pigmentation is few, surface of a wound pain is light, safe without toxic side effect.
Description
Technical field
The present invention relates to medicament for treating scald technical field, and more particularly to a kind of scald medicament and preparation method thereof.
Background technology
Burn and scald is one of relatively common fortuitous event in daily life, and physiology and psychology to patient all cause very big
Influence, bring certain mental wound and physical injury to patient.Particularly occur in specific function position or larger face
Product deep burn is extremely dangerous, and consequence will be serious.According to incompletely statistics, China's average is per Annual occurence rate
The 0.5%~1% of total population, 1/10 client need hospitalization therein.Due to burn and scald treatment technology, the difference of medicine
Different, treatment empyrosis wound surface traditional Chinese and western medicine external used medicine species is a lot of at present, and its method and curative effect are far different, it is desirable to search out more
It is preferable medicine.
The medicine of existing treatment burn and scald is typically all more sticky, by drug application on the surface of burn and scald skin when using,
Allow the efficacy of a drug to be absorbed by the surface of a wound, promote body growth.But the current curative efficacy of a drug is difficult to be rapidly achieved the surface of a wound, the time required to recovery from illness compared with
Long, therapeutic effect is poor.
The content of the invention
Medicament is scalded it is an object of the invention to provide one kind.It has healing to no skin irritation, treatment burn and scald
Hurry up, scar is light, pigmentation is few, surface of a wound pain is light, safe without toxic side effect the advantages of.
Another object of the present invention is to provide a kind of preparation method for scalding medicament, preparation method operating procedure letter
Single, rationally, operating condition is gentle, be easily achieved, with larger prospects for commercial application for preparation process is simple.
The present invention is solved its technical problem and is realized using following technical scheme.
One kind scalds medicament, is mainly made up of the raw material of following parts by weight meter：30~45 parts of honey, 10~15 parts
Honeysuckle, 7~12 parts of Cornu Bubali powder, 2~5 parts of the root of Dahurain angelica, 1~3 part of rhizoma atractylodis, 2~5 parts of the coptis, 0.1~0.3 part
Borneol, 1~5 part of dragon's blood and 20~25 parts of alcohol.
A kind of preparation method for scalding medicament includes：By the honeysuckle of 10~15 parts in parts by weight, 7~12 parts
Cornu Bubali powder, 2~5 parts of the root of Dahurain angelica, 1~3 part of rhizoma atractylodis, 2~5 parts of the coptis and 1~5 part of dragon's blood carry out only successively
The first mixture is obtained after choosing, cleaning, crushing and mixing.Heated after the alcohol that first mixture is added 20~25 parts and boiled
After be filtrated to get the first filtrate.By 30~45 parts of honey and 0.1~0.3 part of borneol in the first dissolved in filtrate.
The beneficial effect of the scald medicament of the embodiment of the present invention and preparation method thereof is：The scald medicament of offer is mainly used
Used as major ingredient, natural honey contains various organic acids, various enzymes, phenolic compound and flavone compound to natural honey
Deng.Not only there is nutritive value and certain healthcare function higher, and be a kind of crude drug with anti-inflammation effect
Thing, the therapeutic effect to wound surface in refractory to treatment and boiling hot burn wound is substantially better than common drug, with having no toxic side effect, without pharmacological dependence
The advantages of property, cheap and wide material sources.Have when natural honey is used for burn and scald surface and go rotten apocenosis, swelling and pain relieving resists
Bacterium anti-inflammatory, promotes the effect of wound healing.Meanwhile, this scalds medicament and uses honeysuckle, Cornu Bubali powder, the root of Dahurain angelica, rhizoma atractylodis, Huang
Company, dragon's blood etc. scald the dispensing that Chinese herbal medicine, alcohol and the borneol of function are scalded as the auxiliary treatment of honey with treatment, enter
One step plays anti-inflammatory, removing toxic substances, the function of analgesic, promotes blood flow, accelerates skin growth, and the effect that enhancing treatment is scalded makes
Wound healing is fast, scar is light, pigmentation is few, pain is light.
Specific embodiment
To make the purpose, technical scheme and advantage of the embodiment of the present invention clearer, below will be in the embodiment of the present invention
Technical scheme be clearly and completely described.Unreceipted actual conditions person, builds according to normal condition or manufacturer in embodiment
The condition of view is carried out.Agents useful for same or the unreceipted production firm person of instrument, are the conventional product that can be obtained by commercially available purchase
Product.
Scald medicament of the embodiment of the present invention and preparation method thereof is specifically described below.
A kind of scald medicament that embodiments of the invention are provided, is mainly made up of the raw material of following parts by weight meter：30
~45 parts of honey, 10~15 parts of honeysuckle, 7~12 parts of Cornu Bubali powder, 2~5 parts of the root of Dahurain angelica, 1~3 part of rhizoma atractylodis, 2~
5 parts of the coptis, 0.1~0.3 part of borneol, 1~5 part of dragon's blood and 20~25 parts of alcohol.
Specifically, the main component of honey is carbohydrate, and content is about 60%~80%, mainly glucose and fructose, sugarcane
Sugared content is less, less than 8%.Also contain plurality of inorganic salt vitamin and organic acid in honey, content is 5% or so.In honey
Also contain fructose oxidizing ferment, glucose oxidase, amylase, reductase, lysozyme etc..Honey can by control trauma surface infestation,
Surface of a wound nutrition is provided, slough, anti-inflammatory, regulation wound healing relevant cell factor is removed and " moist " environment is provided.Tool
For body, honey anti-inflammation and sterilization mechanism has following four：
First, the viscosity high of honey causes that honey can form a natural diaphragm and stick when acting on wound surface
Property barrier, so as to avoid body fluid from being lost in, prevents bacterium infection.The high osmosis of honey then contributes to honey itself to be inhaled from wound
Pus, purification wound top layer are received, while the hypertonic characteristic of honey is unfavorable for the growth of most of microbe, only
A small number of yeast and molds can in 60%~80% hyperosmotic glucose growth from solution, therefore, honey provide hypertonic environment can make
The bacterial cell dehydration of wound surface, causes the physiological of bacterial cell to dry, and then makes Protoplast shrinking, plasmolysis,
Cell death is finally caused, the growth of pathogenic bacteria even effect of complete sterilizing are delayed so as to reach.
Second, the various organic acids (such as citric acid, malic acid, tartaric acid, lactic acid) contained in natural honey and part
Inorganic acid so that honey has relatively low pH in itself, its pH is different with honey category difference.In general, natural honey
PH is respectively less than 4 (average pH is 3.9), and the optimal pH of most bacterial growths is 6.5~7.5, and this allows for application honey
The bacterial growth of wound surface is suppressed, so as to reach the effect of control trauma surface infestation, wound healing.In other honey
Part organic acid such as syringic acid and phenyllactic acid also have good inhibiting effect to bacterium in itself.
Third, containing various enzymes, such as glucose oxidase, fructose oxidizing ferment, amylase, invertase, reduction in honey
Enzyme, lysozyme etc..Wherein glucose oxidase glucose when can produce hydrogen peroxide, hydrogen peroxide is main in honey
Antimicrobial component, hydrogen peroxide can be by discharging the oxygen atom of itself, and the active group with many enzymes in pathogen cell is mercapto
Base junction is closed, and the chemical constitution of enzyme is changed, and then inactivates enzyme, causes bacterial metabolism exception, so as to be risen in wound surface
To the effect of anti-inflammation.Another enzyme with antibacterial action is lysozyme in honey, and the enzyme is mainly blue by dissolving leather
Glucan in family name's positive cell wall composition, causes bacteriolysis, plays bacteriostasis.
Fourth, also containing phenolic compound and flavone compound etc. in honey.Phenolic compound comes from pollen, can cause
The damage of germ permeability of cell membrane, causes the seepage of active component in cell membrane, causes thalline dead.Flavonoids in honey
, essentially from propolis, species is different because nectariferous plant is different for flavone compound, and its Antibacterial Mechanism is also different for compound.
In sum, honey not only has a nutritive value and certain healthcare function higher, and be it is a kind of have it is anti-
The natural drug of bacterium anti-inflammatory effects, the therapeutic effect to wound surface in refractory to treatment and boiling hot burn wound is substantially better than common drug, with nothing
Toxic and side effect, without drug-dependent, cheap and wide material sources the advantages of.
Specifically, honeysuckle can dispelling wind-heat, also kind removing summer-heat blood poison, for various febrile diseases, such as body heat, dermexanthesis, hair
The diseases such as spot, heat toxin sore carbuncle, abscess of throat, equal effect is significant.The clearing heat and detoxicating function of medicament is scalded in strengthening for honeysuckle.
Specifically, Cornu Bubali powder has functions that heat-clearing, cool blood, removing toxic substances.Further enhancing this and scald medicament heat-clearing solution
The function of poison.
Specifically, root of Dahurain angelica energy wind-dispelling, eliminating dampness, detumescence, analgesic.Control headache, pain in the supra-orbital bone, dentalgia, nasosinusitis, cold-dampness stomachache,
Intestines wind anal fistula, leukorrhea with reddish discharge, ulcer sores, skin is dry itches, mange.For scalding during burn surfaces, pain, detumescence row can be eliminated
Purulence, promotes the surface of a wound to heal rapidly.
Specifically, rhizoma atractylodis eliminating dampness, purging intense heat and detonicating is promoting blood circulation and removing blood stasis, its contained jamaicin there is the spasm of lax arrectores pilorum and
Produce analgesic effect.The addition of rhizoma atractylodis imparts the scald effective pain-relieving functions of medicament.
Specifically, the coptis has the effect of heat-clearing and damp-drying drug, purging intense heat and detonicating.For damp and hot feeling of fullness, acid regurgitation is vomitted, rush down dysentery, jaundice,
Unconsciousness due to high fever, heart-fire hyperactivity, dysphoria and insomnia, blood-head tells nosebleed, hot eyes, toothache is quenched one's thirst, carbuncle swells furunculosis；Control eczema, wet sore, ear outward
Suppurate in road.The coptis is antimicrobial, antiprotozoan, has stronger suppression to make to haemolysis row streptococcus, bacillus anthracis, golden staphylococci
With, for scalded skin surface, surface of a wound skin rapid draing, isolation skin and the external world can be helped, shorten cure time.
Specifically, borneol through steam distillation and is recrystallized by composite family Blumea balsamifera cauline leaf or canella borneol camphor tree branches and leaves
And obtain.It can be used to closing card coma, for red eye, swell pain, larynx numbness aphtha, for sore swell and ache curative is not held back after bursting.Also, borneol
Main component borneol there is clearing away heat to and alleviating pain and bacteriostasis.
Specifically, dragon's blood has the good effects of promoting blood circulation and removing blood stasis, swelling and pain relieving, astringing to arrest bleeding.It is babassu Sanguis Draxonis
Resin that fruit oozes out is processed to be made.For traumatic injury, trusted subordinate's stasis caused pain, traumatism and bleeding, sore is not held back good effect
Really.
Specifically, alcohol may act as solvent, and the function with disinfection.
Further, in preferred embodiments of the present invention, in parts by weight, scalding medicament also includes 1~4 part of wound
Face hygroscopic agent.Surface of a wound hygroscopic agent can help surface of a wound skin to dry rapidly, while completely cut off skin and the external world, when shortening surface of a wound recovery from illness
Between.
Used as preferred scheme, hygroscopic agent is selected from one or more in charred RADIX SANGUISORBAE, cuttlebone and calcined gypsum.
Specifically, charred RADIX SANGUISORBAE is the Preparation process product of garden burnet.Garden burnet is rose family burnet herbaceos perennial.Property
Cold, bitter acid is nontoxic；Return liver, lung, kidney and large intestine channel.There is cooling blood and hemostasis, it is clearing heat and detoxicating, train the work(such as clear yin-nourishing, healing up sore and subduing swelling
Effect.Meanwhile, garden burnet has cooling blood and hemostasis, the function of sore removing toxic substances, plays prevention and infection control, eliminates pain, promotes the surface of a wound fast
The effects such as speed healing, garden burnet contains a large amount of tannins, has stronger convergence and pressor effect, it is possible to decrease capillary
Permeability, reduces inflammatory and oozes out, and mitigates tissue edema.Not only have garden burnet above-mentioned by the charred RADIX SANGUISORBAE after the Preparation process of garden burnet
Advantage, moreover it is possible to dry moisture absorption, the part of burn and scald oozed out and produces good suction-operated.
Specifically, cuttlebone has adductor muscle sore, reduces sepage, promotes the dry effect of the surface of a wound.
Specifically, calcined gypsum is the powder or loose block of white, and surface appears the gloss of blush, opaque.Body
Relatively light, matter is soft, frangible, pinch into powder.Odorless, it is lightly seasoned.Hygroscopic, myogenic, the function of hemostasis.
Further, in preferred embodiments of the present invention, in parts by weight, scalding medicament also includes 2~6 parts anti-
Dehydrating agent.Anti- dehydrating agent can be effectively prevented from body fluid loss, prevent bacterium infection.Used as preferred scheme, anti-dehydrating agent is selected from
One or more in sesame oil, soya-bean oil and tea oil.
Further, in preferred embodiments of the present invention, in parts by weight, scalding medicament also includes 0.5~1 part
Preservative, to cause medicament for treating scald agent not perishable, the holding time is extended.In order to be used for large-scale production and sales.
Used as preferred scheme, preservative can be dehydroactic acid sodium, benzoic acid, Sodium Benzoate, sorbic acid, potassium sorbate
And one or more in calcium propionate.
Specifically, dehydroactic acid sodium dehydroactic acid sodium be the another Dai Xin after Sodium Benzoate, potassium sorbate food prevent
Rotten antistaling agent, has good inhibiting effect to mould, saccharomycete, bacterium, extensively using with beverage, food, feed processing
Industry, can extend storage period, it is to avoid loss of going mouldy.Its mechanism of action is effectively to penetrate into cell body, suppresses the breathing of microorganism
Effect, so as to reach the effect such as fresh-keeping moisturizing of anticorrosive mildewproof.
Specifically, benzoic acid can serve as the preservative of food, feed, latex, toothpaste.In acid condition, to mould,
Yeast and bacterium have inhibitory action.
Specifically, Sodium Benzoate lipophile is larger, easy penetration cell film enter cell body in, interference cell film it is penetrating
Property, suppress absorption of the cell membrane to amino acid；Intracellular alkali storage is acidified into cell body internal ionization, and suppresses the breathing of cell
The activity of enzyme system, prevents acetyl coenzyme A condensation reaction, so as to play the purpose of food antiseptic.Sorbic acid and other natural fat
Fat acid is the same, and metabolic processes are participated in human body, and by human consumption and absorption, produces carbon dioxide and water.From safety
From the aspects of property, sorbic acid is a kind of preservative of internationally recognized safety (GRAS), and security is very high.
Specifically, potassium sorbate can effectively suppress the activity of mould, saccharomycete and aerobic bacteria, moreover it is possible to prevent meat poisoning
The harmful microbes such as bacillus, staphylococcus, salmonella grow and breed, but to anaerobic Bacillus and lactobacillus acidophilus etc.
Beneficial microbe is nearly unavailable, and the effect that it restrains development is more stronger than bactericidal action, and the guarantor of food is effectively extended so as to reach
Deposit the time, and keep the local flavor of original food.Its antiseptic effect is 5-10 times of like product Sodium Benzoate.
Specifically, calcium propionate is a kind of new food additive, is the World Health Organization (WHO) and FAO (Food and Agriculture Organization of the United Nation)
(FAO) the safe and reliable food that approval is used and feed mould inhibitor.Calcium propionate has wide to mould, saccharomycete and bacterium etc.
General antibacterial action.
A kind of preparation method of scald medicament that the present invention is provided includes：
By the honeysuckle of 10~15 parts in parts by weight, 7~12 parts of Cornu Bubali powder, 2~5 parts of the root of Dahurain angelica, 1~
3 parts of rhizoma atractylodis, 2~5 parts of the coptis and 1~5 part of dragon's blood obtain after being cleaned successively, cleaned, crushed and being mixed
One mixture；Can effectively be played by the drug effect of the Chinese medicine after crushing.
First mixture being added the is filtrated to get after heat 30~45min at 95~98 DEG C after 20~25 parts of alcohol
One filtrate；
By 30~45 parts of honey and 0.1~0.3 part of borneol in the first dissolved in filtrate.
Scald medicament of the invention and preparation method thereof is described in further detail with reference to embodiments.
Embodiment 1
A kind of scald medicament that the present embodiment is provided, is prepared from the following manner：
By the honeysuckle of 10 parts in parts by weight, 7 parts of Cornu Bubali powder, 2 parts of the root of Dahurain angelica, 1 part of rhizoma atractylodis, 2 parts
The coptis and 1 part of dragon's blood cleaned successively, cleaned, crushed and mixed after obtain the first mixture.
After first mixture to be added the alcohol of 20 weight portions the first filtrate is filtrated to get after heating 30min at 95 DEG C.
By the borneol of the honey of 30 weight portions and 0.1 weight portion in the first dissolved in filtrate.
Embodiment 2
The present embodiment provide it is a kind of scald medicament, the difference with embodiment 1 is, its be prepared by the following method and
Into：
By the honeysuckle of 10 parts in parts by weight, 7 parts of Cornu Bubali powder, 2 parts of the root of Dahurain angelica, 1 part of rhizoma atractylodis, 2 parts
The coptis, 1 part of dragon's blood, 1 part of charred RADIX SANGUISORBAE and 2 parts of sesame oil obtains after being cleaned successively, cleaned, crushed and being mixed
First mixture.
After first mixture to be added the alcohol of 20 weight portions the first filter is filtrated to get after 30~45min of heating at 95 DEG C
Liquid.
By the borneol of the honey of 30 weight portions and 0.1 weight portion in the first dissolved in filtrate.
Embodiment 3
The present embodiment provide it is a kind of scald medicament, the difference with embodiment 1 is, its be prepared by the following method and
Into：
By the honeysuckle of 10 parts in parts by weight, 7 parts of Cornu Bubali powder, 2 parts of the root of Dahurain angelica, 1 part of rhizoma atractylodis, 2 parts
The coptis, 1 part of dragon's blood, 1 part of charred RADIX SANGUISORBAE, 2 parts of sesame oil and 0.5 part of Sodium Benzoate cleaned successively, cleaned, powder
The first mixture is obtained after broken and mixing；Can effectively be played by the drug effect of the Chinese medicine after crushing.
After first mixture to be added the alcohol of 20 weight portions the first filtrate is filtrated to get after heating 30min at 95 DEG C.
By the borneol of the honey of 30 weight portions and 0.1 weight portion in the first dissolved in filtrate.
Embodiment 4
By the honeysuckle of 12 parts in parts by weight, 10 parts of Cornu Bubali powder, 4 parts of the root of Dahurain angelica, 2 parts of rhizoma atractylodis, 4 parts
The coptis, 3 parts of dragon's blood, 2 parts of charred RADIX SANGUISORBAE, 4 parts of sesame oil and 0.8 part of Sodium Benzoate cleaned successively, cleaned, powder
The first mixture is obtained after broken and mixing.
After first mixture to be added the alcohol of 22 weight portions the first filtrate is filtrated to get after heating 35min at 97 DEG C.
By the borneol of the honey of 35 weight portions and 0.2 weight portion in the first dissolved in filtrate.
Embodiment 5
The present embodiment provide it is a kind of scald medicament, the difference with embodiment 1 is, its be prepared by the following method and
Into：
By the honeysuckle of 15 parts in parts by weight, 12 parts of Cornu Bubali powder, 5 parts of the root of Dahurain angelica, 3 parts of rhizoma atractylodis, 5 parts
The coptis, 5 parts of dragon's blood, 4 parts of charred RADIX SANGUISORBAE, 6 parts of sesame oil and 1 part of Sodium Benzoate cleaned, cleaned, crushed successively
And obtain the first mixture after mixing.
After first mixture to be added the alcohol of 25 weight portions the first filtrate is filtrated to get after heating 45min at 98 DEG C.
By the borneol of the honey of 45 weight portions and 0.3 weight portion in the first dissolved in filtrate.
Embodiment 6
The present embodiment provide it is a kind of scald medicament, the difference with embodiment 1 is, its be prepared by the following method and
Into：
By the honeysuckle of 15 parts in parts by weight, 12 parts of Cornu Bubali powder, 5 parts of the root of Dahurain angelica, 3 parts of rhizoma atractylodis, 5 parts
The coptis, 5 parts of dragon's blood, 4 parts of calcined gypsum, 6 parts of soya-bean oil and 1 part of potassium sorbate cleaned, cleaned, crushed successively
And obtain the first mixture after mixing.
After first mixture to be added the alcohol of 25 weight portions the first filtrate is filtrated to get after heating 45min at 98 DEG C.
By the borneol of the honey of 45 weight portions and 0.3 weight portion in the first dissolved in filtrate.
Comparative example 1
Australia's good fortune for commercially buying scalds medicament.
Experimental example 1
The 30-40 Sui male 70 that there is same degree to scald is selected, and is classified as 7 groups.And wherein 6 groups patients of relief exist
Daily 9：00、15：00、22：00 time point, using the scald medicament of embodiment 1~6, was left one group and is used in same time point
The scald medicament of the comparative example 1 of phase homogenous quantities.Observed the situation that every group of wounds are completely recovered in continuous 15 days, and every
3 days records once surface of a wound recovery from illness patient's numbers in every group of patient, record the results are shown in Table 1.
Patient's number of the surface of a wound of table 1. recovery from illness
| Numbering | 3(d) | 6(d) | 9(d) | 12(d) | 15(d) |
| Embodiment 1 | 8 | 2 | 0 | 0 | 0 |
| Embodiment 2 | 8 | 2 | 0 | 0 | 0 |
| Embodiment 3 | 9 | 1 | 0 | 0 | 0 |
| Embodiment 4 | 9 | 1 | 0 | 0 | 0 |
| Embodiment 5 | 9 | 1 | 0 | 0 | 0 |
| Embodiment 6 | 10 | 0 | 0 | 0 | 0 |
| Comparative example 1 | 0 | 0 | 0 | 0 | 2 |
It can be seen from data according to table 1：
The effect of the scald medicament that embodiments of the invention 1~6 are provided is significantly larger than the wound medicament of the offer of comparative example 1
Effect.Also, in parts by weight, when scald medicament each component content be 15 parts honeysuckle, 12 parts of Cornu Bubali powder,
5 parts of the root of Dahurain angelica, 3 parts of rhizoma atractylodis, 5 parts of the coptis, 5 parts of dragon's blood, 4 parts of calcined gypsum, 6 parts of soya-bean oil, 25 parts of alcohol, 45 parts
Honey, 0.3 part of borneol and during 1 part of potassium sorbate, scald the effect that pharmaceutical treatment scalds preferable.
Embodiments described above is a part of embodiment of the invention, rather than whole embodiments.Reality of the invention
The detailed description for applying example is not intended to limit the scope of claimed invention, but is merely representative of selected implementation of the invention
Example.Based on the embodiment in the present invention, what those of ordinary skill in the art were obtained under the premise of creative work is not made
Every other embodiment, belongs to the scope of protection of the invention.
Claims (10)
1. it is a kind of to scald medicament, it is characterised in that the scald medicament is mainly made up of the raw material of following parts by weight meter：
30~45 parts of honey, 10~15 parts of honeysuckle, 7~12 parts of Cornu Bubali powder, 2~5 parts of the root of Dahurain angelica, 1~3 part grey
Art, 2~5 parts of the coptis, 0.1~0.3 part of borneol, 1~5 part of dragon's blood and 20~25 parts of alcohol.
2. scald medicament according to claim 1, it is characterised in that the scald medicament is main by following parts by weight meter
Raw material be made：
32~43 parts of honey, 12~14 parts of honeysuckle, 8~11 parts of Cornu Bubali powder, 3~4 parts of the root of Dahurain angelica, 1.5~2.5 parts
Rhizoma atractylodis, 3~4 parts of the coptis, 0.15~0.25 part of borneol, 2~4 parts of dragon's blood and 21~24 parts of alcohol.
3. scald medicament according to claim 1 and 2, it is characterised in that according to weight fraction meter, the scald medicament is also
Including 1~4 part of surface of a wound hygroscopic agent.
4. scald medicament according to claim 3, it is characterised in that the surface of a wound hygroscopic agent is selected from charred RADIX SANGUISORBAE, cuttlebone
And one or more in calcined gypsum.
5. scald medicament according to claim 4, it is characterised in that according to weight fraction meter, the scald medicament is also wrapped
Include 2~6 parts of anti-dehydrating agent.
6. scald medicament according to claim 5, it is characterised in that the anti-dehydrating agent is selected from sesame oil, soya-bean oil and tea
One or more in oil.
7. scald medicament according to claim 6, it is characterised in that in parts by weight, the scald medicament is also wrapped
Include 0.5~1 part of preservative.
8. scald medicament according to claim 7, it is characterised in that the preservative be selected from dehydroactic acid sodium, benzoic acid,
One or more in Sodium Benzoate, sorbic acid, potassium sorbate and calcium propionate.
9. it is a kind of scald medicament preparation method, it is characterised in that the preparation method of the scald medicament includes：Will be according to weight
The honeysuckle of 10~15 parts of number meter, 7~12 parts of Cornu Bubali powder, 2~5 parts of the root of Dahurain angelica, 1~3 part of rhizoma atractylodis, 2~5 parts
The coptis and 1~5 part of dragon's blood obtain the first mixture after being cleaned successively, cleaned, crushed and being mixed；
Heated after the alcohol that first mixture is added 20~25 parts and be filtrated to get the first filtrate after boiling；
By 30~45 parts of honey and 0.1~0.3 part of borneol in first dissolved in filtrate.
10. it is according to claim 9 scald medicament preparation method, it is characterised in that will first mixture addition
In the step of heating is filtrated to get the first filtrate after boiling after 20~25 parts of alcohol, the heat time is 30~45min, heating temperature
Spend is 95~98 DEG C.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107441258A (en) * | 2017-07-26 | 2017-12-08 | 黄淑珂 | A kind of Wound healing and bone regeneration agent and preparation method thereof |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1432378A (en) * | 2002-01-17 | 2003-07-30 | 傅元庆 | Medicine for treating burns and scalds and its prepn process |
| CN102266406A (en) * | 2011-07-18 | 2011-12-07 | 杨德琛 | Chinese medicinal ointment for treating burn and preparation method |
| CN103550523A (en) * | 2013-11-14 | 2014-02-05 | 任宝菊 | Anti-inflammation and proliferation paste for burns, scalds and ulceration and production method thereof |
| WO2016007776A1 (en) * | 2014-07-09 | 2016-01-14 | Derma Sciences, Inc. | Honey-based foam compositions |
-
2017
- 2017-05-10 CN CN201710325010.6A patent/CN106902211A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1432378A (en) * | 2002-01-17 | 2003-07-30 | 傅元庆 | Medicine for treating burns and scalds and its prepn process |
| CN102266406A (en) * | 2011-07-18 | 2011-12-07 | 杨德琛 | Chinese medicinal ointment for treating burn and preparation method |
| CN103550523A (en) * | 2013-11-14 | 2014-02-05 | 任宝菊 | Anti-inflammation and proliferation paste for burns, scalds and ulceration and production method thereof |
| WO2016007776A1 (en) * | 2014-07-09 | 2016-01-14 | Derma Sciences, Inc. | Honey-based foam compositions |
Non-Patent Citations (5)
| Title |
|---|
| 史书达: "《中国民间秘验偏方大成 精华版》", 31 January 2013, 内蒙古科学技术出版社 * |
| 郭焕春: "《临床骨科医师手册》", 31 August 1994, 天津科学技术出版社 * |
| 郭芳彬: "蜂蜜的抗菌药理研究", 《养蜂科技》 * |
| 高天爱: "《矿物药真伪图鉴及应用》", 28 February 2014, 山西科学技术出版社 * |
| 黄英儒: "《中药临床译优手册》", 30 June 2000, 广西科学技术出版社 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107441258A (en) * | 2017-07-26 | 2017-12-08 | 黄淑珂 | A kind of Wound healing and bone regeneration agent and preparation method thereof |
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