CN106880789A - A kind of medicine for treating rheumatoid arthritis - Google Patents

A kind of medicine for treating rheumatoid arthritis Download PDF

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CN106880789A
CN106880789A CN201710045838.6A CN201710045838A CN106880789A CN 106880789 A CN106880789 A CN 106880789A CN 201710045838 A CN201710045838 A CN 201710045838A CN 106880789 A CN106880789 A CN 106880789A
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medicine
rheumatoid arthritis
root
radix
joint
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CN106880789B (en
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董博
姚洁
袁普卫
李小群
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Shaanxi University of Chinese Medicine
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    • A61K35/62—Leeches; Worms, e.g. cestodes, tapeworms, nematodes, roundworms, earth worms, ascarids, filarias, hookworms, trichinella or taenia
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Abstract

The present invention is a kind of medicine for treating rheumatoid arthritis, is made up of according to appropriate proportioning following medicine：Wild aconite root, aconiti preparata,radix, the root of Dahurain angelica, asarum, earthworm, arisacma consanguineum schott, safflower, Bi Collettii, coix seed, Radix Angelicae Sinensis, placenta, ant, pulverization, raw honey wraps up pelletization, because this formula toxicity is larger, with stopping two days observation drug effects after one week, the present invention is to rheumatoid arthritis, especially clinical manifestation is whole body multiple arthralgia swelling, anchylosis is full stiff feeling, it is distributed symmetrically, different degrees of deformity even is presented, fevers and chills alternate, limbs joint myalgia, joint stuffiness, or pain migration is indefinite, very then joint severe pain, enlargement, it is strong, situations such as deformation, has obvious curative effects, treatment is all made a definite diagnosis for 200 through blood and with modern medicine instrument inspection, result display cures 166, take a turn for the better 11, efficient 88.5%, cure rate 83%.

Description

A kind of medicine for treating rheumatoid arthritis
Technical field
The invention belongs to pure Chinese medicine formula technical field, more particularly to a kind of medicine for treating rheumatoid arthritis.
Background technology
The interpretation of the cause, onset and process of an illness of rheumatoid arthritis is at all for the perverse trends such as perverse trend numbness hinders passages through which vital energy circulates, i.e. wind, cold, wet, heat, phlegm, the stasis of blood are stranded in Limbs tendon and vessel, joint, muscle, passages through which vital energy circulates, qi and blood numbness resistance are obstructed, and general rule is not bitterly.With the passing of time, wasting QI-blood undermines liver kidney to rheumatism, causes element Body healthy tendency virtual loss, healthy tendency both easily invade by empty exopathogen, feels that chill is wet again, and the resistance of qi and blood numbness is not all right, and puckery, or wind, cold, wet, heat are closed in joint Heresy be detained muscles and bones joint, long damages liver kidney yin blood, muscles and bones is lost and is supported, therefore sees that painful swelling of joints, stiff, joint stuffiness, activity hinder Hinder, muscle contraction roulade.Using pain of alleviation and inflammation such as non-steroid anti-inflammatory drug (NSAIDs), antirheumatic drugs (DMARDs) more than doctor trained in Western medicine Disease, improves the state of an illness, and to reduce or delay osteoclasia, can only take stopgap measures to effect a permanent cure, often delay treatment opportunity, aggravate disease, Very then disable.Some utilizations《Synopsis Golden Chamber》、《Essential Recipes for Emergent Use Worth A Thousand Gold》、《Special effect good recipe》、《Bright doctor's fingers and palms》、《Lei Zheng Zhi Cai》In The traditional Chinese herbal decoction treatment of record, effect is not also obvious.
The content of the invention
In order to overcome the shortcoming of above-mentioned prior art, it is an object of the invention to provide a kind of rheumatoid arthritis for the treatment of Medicine, with eliminating evil dredging collateral, dispelling cold and removing dampness, nourshing blood and promoting blood circulation, stagnation resolvation a surname's numbness, filling liver kidney, the feature of replenishing qi and blood.
To achieve these goals, the technical solution adopted by the present invention is：
A kind of medicine for treating rheumatoid arthritis, is made up of the medicine of following weight portion：
6~10g of wild aconite root, 6~10g of aconiti preparata,radix, 10~15g of the root of Dahurain angelica, 6~10g of asarum, 6~10g of earthworm, arisacma consanguineum schott 6~ 10g, safflower 10~20g , 10~15g of Bi Collettii, 10~15g of coix seed, 10~15g of Radix Angelicae Sinensis, 1, placenta, 30~35g of ant.
In being formulated above, because toxicity is larger, medication stops to observe its drug effect in two days after one week, it is to avoid toxic reaction.
After said medicine is prepared, mixing grinds to the powder altogether, raw honey parcel pelletization, orally, 2 balls on the one, daily morning and evening 1 ball is respectively taken, before or after meals are taken, take the course for the treatment of for one within 30 days, take the 1-3 course for the treatment of.
Compared with prior art, the beneficial effects of the invention are as follows：
1) present invention is applied to rheumatoid arthritis, with eliminating evil dredging collateral, dispelling cold and removing dampness, nourshing blood and promoting blood circulation, stagnation resolvation a surname's numbness, tonifying liver Kidney, replenishing qi and blood, and traditional Chinese herbal decoction, such as《Synopsis Golden Chamber》、《Essential Recipes for Emergent Use Worth A Thousand Gold》、《Special effect good recipe》、《Bright doctor's fingers and palms》、《Class is demonstrate,proved Control sanction》Compare, fast with curative effect, the time is short, and cure rate is high, without complication, be difficult the advantages of recurring.
2) this prescription is made up of the taste Chinese medicine of ant, wild aconite root, aconiti preparata,radix, root of Dahurain angelica etc. 12.Ant, placenta are monarch drug in a prescription, are amounted to It is clearing and activating the channels and collaterals, the work(of tonifying kidney and benefiting sperm.Wild aconite root, aconiti preparata,radix dispelling wind and eliminating dampness, antalgic；The root of Dahurain angelica, asarum relieving exterior syndrome and dispelling cold, wind-dispelling stop Bitterly；Arisacma consanguineum schott is eliminating dampness and eliminating phlegm, expelling wind and relieving convulsion, mass dissipating and swelling eliminating.Earthworm is tonified the liver and kidney, dredging collateral antispastic, is assistant with this medicine, can be strengthened and be dispelled Wind, dredging collateral, the power of only convulsion analgesic.In side and with safflower invigorate blood circulation, blood stasis removing analgesic；Bi Collettii, coix seed dampness removing go turbid, and wind-dispelling is removed Numbness, Chinese angelica blood supplementing, promoting blood circulation, menstruction regulating and pain relieving；With in, coordinating the drug actions of a prescription plays the effect of wind expelling stagnation removing, promoting blood circulation and stopping pain to honey QI invigorating altogether.Together When early stage research show：Full side can reduce platelet adhesion reaction and capillary permeability, reduction blood fat, anti-inflammatory and antalgic and anti- Control the generation of atrophic diseases, mitigate the inflammatory reaction in rheumatoid arthritis pathogenic process, improve Hemorheology and TBF metabolic disorder, reduces free radical, protection blood vessel endothelium and can improve fibrinolytic, is conducive to preventing and removing class wind The formation of the moist factor.So as to play prevention and treatment rheumatoid arthritis, promote injury tissue reparation, alleviate clinical condition Shape.
3) by clinical examination, the present invention is whole body multiple arthralgia to rheumatoid arthritis, especially clinical manifestation Swelling, anchylosis or be full stiff feeling is distributed symmetrically, or even different degrees of deformity is presented, and fevers and chills alternate, limbs are closed Section myalgia, joint stuffiness, or pain migration is indefinite, very then joint severe pain, enlargement, strong, deformation situations such as have it is obvious Curative effect, all makes a definite diagnosis for 200 treatment through blood and with modern medicine instrument inspection, as a result shows healing 166, improvement 11 Example, efficient 88.5%, cure rate 83%.
Specific embodiment
The present invention is described in further details with reference to embodiment.
Embodiment one
A kind of medicine for treating rheumatoid arthritis, is made up of the medicine of following weight portion：
Wild aconite root 6g, aconiti preparata,radix 6g, root of Dahurain angelica 10g, asarum 6g, earthworm 6g, arisacma consanguineum schott 10g, safflower 20g , Bi Collettii 15g, the heart of a lotus seed Seed of jog's tears 15g, Radix Angelicae Sinensis 12g, 1, placenta, 1 bag of ant (35g)
After said medicine is prepared, mixing grinds to the powder altogether, raw honey parcel pelletization, orally, 2 balls on the one, daily morning and evening 1 ball is respectively taken, before or after meals are taken, take the course for the treatment of for one within 30 days, take the 1-3 course for the treatment of.
30 patients of rheumatoid arthritis, limbs joint, myalgia are aching and tired usually, joint stuffiness, and pain is in trip The property walked, from the beginning of have the tables such as foul wind, heating demonstrate,prove, thin white fur of tongue, floating pulse.We are taken by said medicine composition and method, according to pain Pain visual analogue scale scale (VAS) and patient clinical symptom improvement rate, in drug administration 2 weeks, 1 month, 3 months assessment clinics Curative effect, observes adverse reactions of patients.Result finds 30 patient with rheumatoid arthritis, in addition to 3 have no obvious curative effects, remaining VAS scorings (7.07 ± 0.94) is remarkably decreased (P compared with VAS scorings (2.07 ± 0.43) before treatment after patient's treatment< 0.05)；Clinical acceptance rate is 90%, and patient is significantly improved at aspects such as pain, functional activities.
Embodiment two
A kind of medicine for treating rheumatoid arthritis, is made up of the medicine of following weight portion：
Wild aconite root 9g, aconiti preparata,radix 9g, root of Dahurain angelica 12g, asarum 12g, earthworm 6g, arisacma consanguineum schott 10g, safflower 20g , Bi Collettii 15g, the heart of a lotus seed Seed of jog's tears 15g, Radix Angelicae Sinensis 12g, 1, placenta, 1 bag of ant (30g)
Usage is with embodiment one.
40 patients of rheumatoid arthritis, limbs joint pain usually, sharp ache, position is fixed, and meets cold then pain Very, obtain hot, subtract bitterly, joint joint stuffiness or has creeping chill at local skin, and tongue nature is light, thin white fur of tongue, stringy and tense pulse.By above-mentioned medicine Thing is constituted and method takes we, and its clinical efficacy is observed within 2 weeks, 3 months in drug administration, while before and after recording two groups of treatments Function of joint scores, and its clinical efficacy and function of joint improving action be not obvious after drug administration 2 weeks, is taking 3 months Afterwards, all patients do not occur adverse reaction.Result is shown in 40 patient with rheumatoid arthritis, except 4 patients are without obvious Outside curative effect, overall clinical efficacy rate is 90% after remaining patient treatment, VAS before joint motion scoring (10.37 ± 5.94) and treatment Scoring (25.97 ± 11.43) is compared to significantly improving (P<0.05)；Illustrate that we have aobvious at aspects such as pain, functional activities Write curative effect.
Embodiment three
A kind of medicine for treating rheumatoid arthritis, is made up of the medicine of following weight portion：
Wild aconite root 6g, aconiti preparata,radix 6g, root of Dahurain angelica 10g, asarum 6g, earthworm 6g, arisacma consanguineum schott 12g, safflower 20g , Bi Collettii 12g, the heart of a lotus seed Seed of jog's tears 12g, Radix Angelicae Sinensis 12g, 1, placenta, 1 bag of ant (35g)
Usage is with embodiment one.
35 patients of rheumatoid arthritis, limbs joint, muscle are aching and tired usually, weigh, pain, and swelling is careless and sloppy, close Section activity is unfavorable, and numbness is meciless, and tongue nature is light, white and greasy fur, soft and moderate pulse.We are taken by said medicine composition and method, According to VAS scorings and patient clinical satisfaction, in drug administration 1 month, 3 months assessment clinical efficacies, observation patient is bad anti- Should.Result finds in 35 patient with rheumatoid arthritis that the clinical symptoms for having 5 patients do not have any improvement, remaining patient VAS scorings (8.17 ± 0.64) is remarkably decreased (P compared with VAS scorings (1.92 ± 0.57) before treatment after treatment<0.05)；Face It is 85.7% that bed is satisfied.
Example IV
A kind of medicine for treating rheumatoid arthritis, is made up of the medicine of following weight portion：
Wild aconite root 12g, aconiti preparata,radix 12g, root of Dahurain angelica 10g, asarum 6g, earthworm 6g, arisacma consanguineum schott 10g, safflower 20g , Bi Collettii 15g, Coix seed 15g, Radix Angelicae Sinensis 12g, 1, placenta, 1 bag of ant (30g)
Usage is with embodiment one.
37 patients of rheumatoid arthritis, migrans arthralgia, can relate to one or more joints usually, activity Inconvenience, local scorching hot redness, can not touch bitterly, obtain cold, relax, and can have subcutaneous nodule or erythema, be often accompanied by heating, foul wind, sweating, The constitutional symptoms such as thirsty, dysphoria, red tongue body, tongue fur Huang or yellow greasy, slippery and rapid pulse.This is taken by said medicine composition and method Side, its clinical efficacy is observed for 3 months in drug administration, while recording the VAS scorings before and after two groups of treatments, is being taken 3 months Afterwards, all patients do not occur adverse reaction.Result shows in 37 patient with rheumatoid arthritis, faces except 6 patients take Bed symptom is not improved, and overall clinical efficacy rate is 83.8%, VAS scorings (8.21 ± 1.04) and treatment after remaining patient treatment Preceding VAS scoring (2.01 ± 1.13) is compared to significantly improving (P<0.05)；Illustrate that we's treatment Rheumatoid Arthritis show Write.
Embodiment five
A kind of medicine for treating rheumatoid arthritis, is made up of the medicine of following weight portion：
Wild aconite root 9g, aconiti preparata,radix 9g, root of Dahurain angelica 12g, asarum 9g, earthworm 6g, arisacma consanguineum schott 9g, safflower 20g , Bi Collettii 12g, Job's tears Benevolence 12g, Radix Angelicae Sinensis 12g, 1, placenta, 1 bag of ant (30g)
Usage is with embodiment one.
29 patients of rheumatoid arthritis, muscle arthrosis shouting pain usually, fixation is not moved, the purple dark, swelling of articular skin, By it is harder, limbs stubbornness or is weighed, the hard deformation in joint sexual anesthesia, and joint stuffiness has scleroma, ecchymosis, and complexion is dim black, tongue nature It is purple dark, white and greasy fur, stringy and hesitant pulse.We are taken by said medicine composition and method, is faced in drug administration 1 month, assessment in 3 months Bed curative effect, observes adverse reactions of patients.The front and rear arthralgia degree for the treatment of is determined using VAS point systems (visual simulation rating method) Evaluated, as a result in 29 patients in addition to 3 are not improved, before remaining patient treatment VAS pain scores for (7.42 ± 0.35) divide, 1 month after treatment (3.63 ± 0.36) point, 3 months after treatment (2.73 ± 0.23) point.The VAS of 3 months after treatment Pain scores are substantially less than (P before treatment<0.05), 1 month VAS pain scores with 3 months compares after treatment, without statistics meaning Justice (P>0.05), overall clinical efficacy rate is 89.7%.
Embodiment six
A kind of medicine for treating rheumatoid arthritis, is made up of the medicine of following weight portion：
Wild aconite root 6g, aconiti preparata,radix 6g, root of Dahurain angelica 12g, asarum 6g, earthworm 6g, arisacma consanguineum schott 10g, safflower 15g , Bi Collettii 12g, the heart of a lotus seed Seed of jog's tears 12g, Radix Angelicae Sinensis 10g, 1, placenta, 1 bag of ant (35g)
Usage is with embodiment one.
29 patients of rheumatoid arthritis, limbs joint, myalgia are aching and tired usually, joint stuffiness, wasting and atrophy of muscle, Aversion to cold and cold limbs, impotence, seminal emission, hectic fever due to yin labor heat, vexed dry, tongue nature is light red, thin white fur of tongue or few Tianjin, and deeptensepulse is counted accurately.By above-mentioned Medicine is constituted and method takes we, in drug administration 1 month, 2 months, 3 months observed and recorded treatment Patients Before And After clinical conditions Shape and VAS value changes.In 29 patients of result in addition to 2 have no and have clear improvement, remaining patient VAS scorings after treatment (7.45 ± 1.09) substantially reduce before (2.63 ± 0.91) relatively treat, the statistically significant (P of difference<0.05), total effective rate is 93.1%, illustrate that we's treatment atrophic diseases curative effect determines, it is safe.
The present invention and traditional Chinese herbal decoction, such as《Synopsis Golden Chamber》、《Essential Recipes for Emergent Use Worth A Thousand Gold》、《Special effect good recipe》、《Bright doctor's fingers and palms》、 《Lei Zheng Zhi Cai》Compare, fast with curative effect, the time is short, and cure rate is high, without complication, be difficult the advantages of recurring.

Claims (3)

1. a kind of medicine for treating rheumatoid arthritis, it is characterised in that be made up of the medicine of following weight portion：
6~10g of wild aconite root, 6~10g of aconiti preparata,radix, 10~15g of the root of Dahurain angelica, 6~10g of asarum, 6~10g of earthworm, 6~10g of arisacma consanguineum schott, Safflower 10~20g , 10~15g of Bi Collettii, 10~15g of coix seed, 10~15g of Radix Angelicae Sinensis, 1, placenta, 30~35g of ant.
2. the medicine of rheumatoid arthritis is treated according to claim 1, it is characterised in that by the medicine group of following weight portion Into：
Wild aconite root 6g, aconiti preparata,radix 6g, root of Dahurain angelica 10g, asarum 6g, earthworm 6g, arisacma consanguineum schott 10g, safflower 20g , Bi Collettii 15g, coix seed 15g, Radix Angelicae Sinensis 12g, 1, placenta, ant 35g.
3. the preparation method of the medicine of rheumatoid arthritis is treated described in claim 1, it is characterised in that according to component by medicine After preparing, mixing grinds to the powder altogether, raw honey parcel pelletization.
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CN1386519A (en) * 2001-05-18 2002-12-25 韩树德 Plaster for treating rheumatism
CN102145127A (en) * 2010-11-09 2011-08-10 杨相德 Medicament for treating rheumatoid arthritis and preparation method thereof
CN105902982A (en) * 2016-05-24 2016-08-31 内蒙古中安类风湿骨关节病专科医院有限责任公司 Traditional Chinese medicine composition for treating arthralgia caused by cold stasis stagnation

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Publication number Priority date Publication date Assignee Title
CN1277042A (en) * 2000-04-07 2000-12-20 姜宾 Prolifration treating bolus
CN1386519A (en) * 2001-05-18 2002-12-25 韩树德 Plaster for treating rheumatism
CN102145127A (en) * 2010-11-09 2011-08-10 杨相德 Medicament for treating rheumatoid arthritis and preparation method thereof
CN105902982A (en) * 2016-05-24 2016-08-31 内蒙古中安类风湿骨关节病专科医院有限责任公司 Traditional Chinese medicine composition for treating arthralgia caused by cold stasis stagnation

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朱峪英: "中西医结合治疗类风湿关节炎36例疗效观察", 《华南国防医学杂志》 *
罗世东: "温通法内外合治膝关节骨性关节炎临床观察", 《广西中医药》 *

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