CN104623607B - A kind of Chinese medicine composition for treating rheumatic and rheumatoid diseases - Google Patents
A kind of Chinese medicine composition for treating rheumatic and rheumatoid diseases Download PDFInfo
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Abstract
The present invention relates to a kind of Chinese medicine composition for treating rheumatic and rheumatoid diseases, and it includes the material of following parts by weight：60 90 parts of 50 90 parts of pseudo-ginseng, 30 60 parts of frankincense, 30 60 parts of myrrh, 10 20 parts of vomiting nut, 20 30 parts of stir-baked SQUAMA MANITIS, 20 60 parts of Radix Angelicae Sinensis, 20 60 parts of Ligusticum wallichii, 20 60 parts of monkshood, 20 60 parts of radix aconiti agrestis, 30 90 parts of ground bettle, 30 90 parts of the root of Dahurain angelica, 30 90 parts of safflower, 15 30 parts of akebi, 30 50 parts of centipede, 10 15 parts of scorpio, 30 90 parts of dipsacus root, 60 90 parts of zaocys dhumnade, 30 60 parts of earthworm, 30 60 parts of caulis sinomenii, 30 60 parts of caulis piperis futokadsurae, 30 60 parts of caulis trachelospermi and rhizoma zingiberis.Chinese medicine composition of the present invention interacts, synergy, evident in efficacy, highly widelys popularize.
Description
Technical field
The present invention relates to field of medicaments, relates in particular to a kind of Chinese medicine composition for treating rheumatic and rheumatoid diseases.
Background technology
Rheumatoid arthritis is also known as rheumatoid, is a kind of not yet clear chronic systemic inflammation disease of cause of disease, with
Lesion is main clinical manifestation outside chronic, symmetry, more synovial joints inflammation and joint, belongs to autoimmune inflammatory disease.The disease
The Minor articulus such as hand, wrist, foot are apt to occur in, recurrent exerbation, are symmetric.There are joint red and swollen heat pain and dysfunction, late period early stage
Joint may occur in which different degrees of stiff deformity, and with the atrophy of bone and skeletal muscle, easily disable.The rheumatoid arthritis cause of disease
Complexity, belong to the traditional Chinese medical science " bi Zheng " category.Numbness is the obstructed meaning of blocking, the damp and hot heresy of chill, attacks human body in an opponent's defence, causes qi and blood to be transported
Capable not smooth, channels and collaterals are tired stagnant；Or phlegm-turbidity and blood stasis blood, hinder in channels and collaterals, go deep into joint tendon and vessel, can all fall ill.The generation of other numbness disease also with
The prosperity and decline of constitution and weather conditions, living environment have substantial connection.
The content of the invention
It is an object of the invention to provide a kind of Chinese medicine composition for treating rheumatic and rheumatoid diseases.
In order to realize the purpose of the present invention, the present invention provides a kind of Chinese medicine composition for treating rheumatic and rheumatoid diseases, and it is wrapped
Material containing following parts by weight：Pseudo-ginseng 50-90 parts, frankincense 30-60 parts, myrrh 30-60 parts, vomiting nut 10-20 parts, stir-baked SQUAMA MANITIS
20-30 parts, Radix Angelicae Sinensis 20-60 parts, Ligusticum wallichii 20-60 parts, monkshood 20-60 parts, radix aconiti agrestis 20-60 parts, ground bettle 30-90 parts, root of Dahurain angelica 30-
90 parts, safflower 30-90 parts, akebi 15-30 parts, centipede 30-50 parts, scorpio 10-15 parts, dipsacus root 30-90 parts, zaocys dhumnade 60-90
Part, earthworm 30-60 parts, caulis sinomenii 30-60 parts, caulis piperis futokadsurae 30-60 parts, caulis trachelospermi 30-60 parts and rhizoma zingiberis 60-90 parts.
Preferably, the Chinese medicine composition of described treatment rheumatic and rheumatoid diseases includes the material of following parts by weight：Pseudo-ginseng 80
Part, 50 parts of frankincense, 50 parts of myrrh, 10 parts of Semen Strychni (processed), 25 parts of stir-baked SQUAMA MANITIS, 30 parts of Radix Angelicae Sinensis, 50 parts of Ligusticum wallichii, 20 parts of monkshood, radix aconiti agrestis
20 parts, 35 parts of ground bettle, 50 parts of the root of Dahurain angelica, 60 parts of safflower, 15 parts of akebi, 40 parts of centipede, 10 parts of scorpio, 50 parts of dipsacus root, zaocys dhumnade
80 parts of 70 parts, 50 parts of earthworm, 50 parts of caulis sinomenii, 50 parts of caulis piperis futokadsurae, 50 parts of caulis trachelospermi and rhizoma zingiberis.
Preferably, the Chinese medicine composition of described treatment rheumatic and rheumatoid diseases also includes the material of following parts by weight：Three
10 parts of pin, seven-star grass 15 parts, 10 parts of peristrophe, 8 parts of three branches and leaves, 8 parts of big Sorrel, mountain flower give birth to 6 parts, 7 parts of yunnan supplejack root,
8 parts of 9 parts of yellow angledtwig magnoliavine root stem and leaf, 5 parts of seven lotus of sheep, 7 parts of blumea, 9 parts of Flos Hibisci Mutabilis, 7 parts of pilea cadierei and fermented soya bean grass.
Preferably, the Chinese medicine composition can be tablet, dispersible tablet, capsule, pill or vina.
The present invention also provides purposes of the composition in the Chinese medicine for preparing treatment rheumatic and rheumatoid diseases, and the composition includes
The material of following parts by weight：Pseudo-ginseng 50-90 parts, frankincense 30-60 parts, myrrh 30-60 parts, vomiting nut 10-20 parts, stir-baked SQUAMA MANITIS 20-
30 parts, Radix Angelicae Sinensis 20-60 parts, Ligusticum wallichii 20-60 parts, monkshood 20-60 parts, radix aconiti agrestis 20-60 parts, ground bettle 30-90 parts, root of Dahurain angelica 30-90
Part, safflower 30-90 parts, akebi 15-30 parts, centipede 30-50 parts, scorpio 10-15 parts, dipsacus root 30-90 parts, zaocys dhumnade 60-90 parts,
Earthworm 30-60 parts, caulis sinomenii 30-60 parts, caulis piperis futokadsurae 30-60 parts, caulis trachelospermi 30-60 parts and rhizoma zingiberis 60-90 parts.
Preferably, the composition includes the material of following parts by weight：80 parts of pseudo-ginseng, 50 parts of frankincense, 50 parts of myrrh, horse processed
10 parts of money, 25 parts of stir-baked SQUAMA MANITIS, 30 parts of Radix Angelicae Sinensis, 50 parts of Ligusticum wallichii, 20 parts of monkshood, 20 parts of radix aconiti agrestis, 35 parts of ground bettle, 50 parts of the root of Dahurain angelica,
60 parts of safflower, 15 parts of akebi, 40 parts of centipede, 10 parts of scorpio, 50 parts of dipsacus root, 70 parts of zaocys dhumnade, 50 parts of earthworm, 50 parts of caulis sinomenii,
80 parts of 50 parts of caulis piperis futokadsurae, 50 parts of caulis trachelospermi and rhizoma zingiberis.
Preferably, the composition also includes the material of following parts by weight：10 parts of barberry, seven-star careless 15 parts, nine lions
Sub- 10 parts of grass, 8 parts of three branches and leaves, 8 parts of big Sorrel, 6 parts of mountain flower life, 7 parts of yunnan supplejack root, 9 parts of yellow angledtwig magnoliavine root stem and leaf, 5 parts of seven lotus of sheep, reddish tone
8 parts of 7 parts of grass, 9 parts of Flos Hibisci Mutabilis, 7 parts of pilea cadierei and fermented soya bean grass.
Preferably, the Chinese medicine can be tablet, dispersible tablet, capsule, pill or vina.
Chinese medicine composition of the present invention interacts, synergy, evident in efficacy, highly widelys popularize.
Embodiment
The present invention is further illustrated below by embodiment.It should be understood that embodiments of the invention are to be used to illustrate
The present invention rather than limitation of the present invention.The present invention is belonged to according to the simple modifications that the essence of the present invention is carried out to the present invention
Claimed scope.Unless otherwise stated, the percentage in the present invention is percetage by weight.
The vina of the present invention of embodiment 1
Weigh 80 grams of pseudo-ginseng, 50 grams of frankincense, 50 grams of myrrh, 10 grams of Semen Strychni (processed), 25 grams of stir-baked SQUAMA MANITIS, 30 grams of Radix Angelicae Sinensis, Ligusticum wallichii
50 grams, 20 grams of monkshood, 20 grams of radix aconiti agrestis, 35 grams of ground bettle, 50 grams of the root of Dahurain angelica, 60 grams of safflower, 15 grams of akebi, 40 grams of centipede, scorpio 10
Gram, 50 grams of dipsacus root, 70 grams of zaocys dhumnade, 50 grams of earthworm, 50 grams of caulis sinomenii, 50 grams of caulis piperis futokadsurae, 80 grams of 50 grams of caulis trachelospermi and rhizoma zingiberis, add
Enter 4000 milliliters of absolute ethyl alcohols, impregnate 7 days, filter under conditions of room temperature closing, filtrate produces.
The vina of the present invention of embodiment 2
Weigh 80 grams of pseudo-ginseng, 50 grams of frankincense, 50 grams of myrrh, 10 grams of Semen Strychni (processed), 25 grams of stir-baked SQUAMA MANITIS, 30 grams of Radix Angelicae Sinensis, Ligusticum wallichii
50 grams, 20 grams of monkshood, 20 grams of radix aconiti agrestis, 35 grams of ground bettle, 50 grams of the root of Dahurain angelica, 60 grams of safflower, 15 grams of akebi, 40 grams of centipede, scorpio 10
Gram, 50 grams of dipsacus root, 70 grams of zaocys dhumnade, 50 grams of earthworm, 50 grams of caulis sinomenii, 50 grams of caulis piperis futokadsurae, 50 grams of caulis trachelospermi, 80 grams of rhizoma zingiberis, three
10 grams of pin, 15 grams of seven-star grass, 10 grams of peristrophe, 8 grams of three branches and leaves, 8 grams of big Sorrel, mountain flower give birth to 6 grams, yunnan supplejack root 7
Gram, 9 grams of yellow angledtwig magnoliavine root stem and leaf, 5 grams of seven lotus of sheep, 7 grams of blumea, 9 grams of Flos Hibisci Mutabilis, 7 grams of pilea cadierei and fermented soya bean grass 8 grams, add 4000
Milliliter absolute ethyl alcohol, impregnate 7 days, filter under conditions of room temperature closing, filtrate produces.
Experimental example
Diagnostic criteria
With reference to the standard of American society of rheumatism amendment in 1987, its diagnostic criteria needs 7 in following projects, in 1-5
Xiang Zhong, joint symptoms at least have to last for 6 weeks.
(1) morning stiffness (it is more than hour to continue I).
(2) pain or there is tenderness (being seen by doctor) during at least one joint motion.
(3) at least one arthroncus (soft tissue plumpness or hydrops rather than osteoproliferation, seen by doctor).
(4) at least another arthroncus (is seen, two joint involvement institute interludes should be no more than 3 by doctor
Individual month).
(5) symmetry arthroncus (being seen by doctor), while the same joint of body both sides is invaded (if invaded
Need not be full symmetric when proximal phalangeal joints, metacarpophalangeal joints or toe joint).Involving for distal interphalangeal joint can not meet this
Standard.
(6) bone protrusion or juxtra-articular stretch the subcutaneous nodule (being seen by doctor) of side.
(7) the X-ray film finding of standard (outside deossification hyperplasia, it is necessary to the presence of the osteoporosis near affected joints).
(8) rheumatoid factor positive.
(9) mucoprotein solidification is bad in synovial fluid.
(10) there are three or more in following synovial membrane pathological changes：Obvious fine hair hyperplasia；Top layer synovial cell increases
Give birth to and in paliform；Obvious chronic inflammatory cell (predominantly lymphocyte and thick liquid cell) infiltration and the trend for forming lymph node；
Top layer or the fibrin deposition of interstitial densification；Focal necrosis.
(11) display centre area meronecrosis stove is answered by the Histological change in subcutaneous nodule, around the macrophage of palisade hyperplasia
Cell and outermost chronic cell infiltration.
According to above-mentioned standard, 60 rheumatic and rheumatoid patients are selected, wherein man 30, female 30, age 25-63 year,
It is average 41 years old.It is two groups, respectively treatment group 1 and treatment group 2 by patient, every group has 30 patients.Two groups of Genders, years
Age, the course of disease, symptom there are no significant difference, have comparativity (P ＞ 0.05).
Treatment group 1 is treated using the vina prepared in embodiment 1, twice daily, dips 50 grams of wine using gauze every time
Agent is uniformly applied to arthritis pain sore spot, wipes to skin and generates heat slightly, continuous treatment 2 months.
Treatment group 2 is treated using the vina prepared in embodiment 2, twice daily, dips 50 grams of wine using gauze every time
Agent is uniformly applied to arthritis pain sore spot, wipes to skin and generates heat slightly, continuous treatment 2 months.
Criterion of therapeutical effect
It is wet according to relevant chill in the Chinese medical disease Standardization of diagnosis and curative effect of State Administration of Traditional Chinese Medicine's nineteen ninety-five issuing and implementation
Type rheumatism efficacy assessment standard.
(1) clinical cure：Arthralgia, swelling disappear, and movable function is normal, and laboratory examination is normal.
(2) take a turn for the better：Arthralgia, swelling mitigate, and movable function takes a turn for the better, and laboratory examination has improvement.
(3) it is not cured：Arthralgia, swelling and laboratory examination are unchanged.
Statistical method
Experimental data is handled and analyzed using the softwares of SPSS 13.0, measurement data is with mean ± standard deviation
Represent, examined using t, enumeration data uses x2Examine, P ＜ 0.05 represent that difference has statistical significance.
As a result
By treatment, for treatment group 1, clinical cure 11, take a turn for the better 13, not more 6, total effective rate 80% is right
In treatment group 2, clinical cure 18, take a turn for the better 10, not more 2, total effective rate 93.3%, two groups of total effective rate comparing differences
Statistically significant (P ＜ 0.05).
Adverse reaction and toxic side effect supervision
By detect the blood pressure of patient, pulse, whether occur Nausea and vomiting, dizziness clinical symptoms it is bad anti-to judge
Should.It was found that the systolic pressure of all patients is between 90-140mmHg, diastolic pressure between 60-90mmHg, pulse is 60-100 times/
Minute, blood pressure and pulse is all within normal range (NR), and Nausea and vomiting, the clinical symptoms of dizziness does not occur.This explanation
The pharmaceutical composition of the present invention does not have obvious adverse reaction, and then proves that medicine does not have obvious toxic side effect for human body.
Claims (2)
1. a kind of Chinese medicine composition for treating rheumatic and rheumatoid diseases, it is characterised in that it is made up of following method：Weigh pseudo-ginseng 80
Gram, 50 grams of frankincense, 50 grams of myrrh, 10 grams of Semen Strychni (processed), 25 grams of stir-baked SQUAMA MANITIS, 30 grams of Radix Angelicae Sinensis, 50 grams of Ligusticum wallichii, 20 grams of monkshood, radix aconiti agrestis
20 grams, 35 grams of ground bettle, 50 grams of the root of Dahurain angelica, 60 grams of safflower, 15 grams of akebi, 40 grams of centipede, 10 grams of scorpio, 50 grams of dipsacus root, zaocys dhumnade
80 grams of 70 grams, 50 grams of earthworm, 50 grams of caulis sinomenii, 50 grams of caulis piperis futokadsurae, 50 grams of caulis trachelospermi and rhizoma zingiberis, add 4000 milliliters of anhydrous second
Alcohol, impregnate 7 days, filter under conditions of room temperature closing, filtrate produces.
2. purposes of the composition described in claim 1 in the Chinese medicine for preparing treatment rheumatic and rheumatoid diseases.
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Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105770063A (en) * | 2016-05-17 | 2016-07-20 | 孙福强 | Traditional Chinese medicinal composition for treating rheumatoid disease |
| CN108392613A (en) * | 2018-05-08 | 2018-08-14 | 耿全好 | A kind of drug and preparation method thereof for treating cough |
| CN109248288A (en) * | 2018-11-28 | 2019-01-22 | 饶正军 | A kind of drug and preparation method thereof for treating rheumatism |
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