CN106852333A - A kind of microbicide compositions containing ascorbic acid and thifluzamide - Google Patents
A kind of microbicide compositions containing ascorbic acid and thifluzamide Download PDFInfo
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- CN106852333A CN106852333A CN201611253144.3A CN201611253144A CN106852333A CN 106852333 A CN106852333 A CN 106852333A CN 201611253144 A CN201611253144 A CN 201611253144A CN 106852333 A CN106852333 A CN 106852333A
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- Prior art keywords
- ascorbic acid
- thifluzamide
- compositions containing
- microbicide compositions
- preparation
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/02—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having no bond to a nitrogen atom
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/02—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
- A01N43/04—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom
- A01N43/06—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom five-membered rings
- A01N43/08—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom five-membered rings with oxygen as the ring hetero atom
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- Life Sciences & Earth Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention discloses a kind of microbicide compositions containing ascorbic acid and thifluzamide, it is prepared from by the raw material of following weight percents：Ascorbic acid 0.001%~90%, thifluzamide 0.1% -80%, dispersant 1%~15%, cosolvent 0.5%~15%, stabilizer 0%~5%, solvent 10%~98%, balance of distilled water.Preparation is simple for the present composition, Product quality and safety reliability, has a wide range of application, and has significant sterilized and the effect of increasing income to paddy rice, with the fabulous prospect of marketing and huge economic results in society.
Description
Technical field
The invention belongs to agricultural technology field, and in particular to a kind of antimicrobial combination containing ascorbic acid and thifluzamide
Thing.
Background technology
Rice blast is one of important disease of paddy rice, can cause the significantly underproduction, the underproduction 40% -50% when serious, or even
No kernels or seeds are gathered, as in a year of scarcity, and this disease has generation in various regions, wherein being occured as with leaf portion, section portion many, the different degrees of underproduction can be caused after generation,
Especially panicle blast or section pest occurs early and weighs, and can cause dead ears so that total crop failure.In recent years, Guangdong rice blast year occurring area is not
Less than 500,000 mu, and appearance increases trend year by year, and local great outburst is much, and at present, rice blast is likely to occur in province
Any year, any season in domain.
Also known as moire disease, popular name spends sufficient stalk, rotten pin pest, features spot to rice sheath blight disease, is fallen ill by Rhizoctonia solani Kuhn infection,
It is many to occur under high temperature, super-humid conditions.Banded sclerotial blight causes harm seriously in South Rice Region of China, be Major Diseases in current Rice Production it
One, the disease prevents paddy rice from earing, or the not plump paddy of heading is more, and grain declines again.
Banded sclerotial blight, rice blast are that paddy rice incidence is high, and occurring area is wide, the strong Major Diseases of causing harm property degree, in paddy rice
Cultivation peasant needs various medicaments to be used in mixed way or repeatedly dispenser can be only achieved and prevent and treat purpose.
Thifluzamide (thifluzamide) belongs to benzene oxanamide class, and with stronger systemic action, the lasting period is long.Mainly
Effect is to suppress the acidohydrogenase in disease fungus tricarboxylic acid cycle, causes thalline dead.In Chinese patent literature [application number:
2015104234741, application publication number:CN105052958A, a kind of multifunctional paddy bactericidal composition] relate to, in one kind
Thifluzamide and Enestroburin/fenoxanil/Prochloraz are used in combination in multifunctional paddy bactericide, wherein ratio be 1~
20: 1~20：1~20：1~20,
As the people preserve the ecological environment, development green agriculture and the cry for ensuring food safety grow to even greater heights, and national governments are confused
It is confused to take the measure for reducing or limiting the production of some chemical pesticides and use.Efficiently, low toxicity, free of contamination biological pesticide turn into
Pesticide manufacturing, exploitation and the focus applied.Biological pesticide is the important substance basis for ensureing food security and social stability, is anti-
The effective means and permanent mechanism of great plant pest are newly sent out, are recurred in control, are the important technology guarantees of agroecological environment.
In view of studying above, the present invention provides a kind of microbicide compositions containing ascorbic acid and thifluzamide, it is intended to
By biological technique method, increase the nutritional quality and enhancing paddy rice of paddy rice resistance in itself, bactericidal property is good, it is low toxicity, low
Residual, so as to realize the increasing both production and income of crops, lifts agricultural performance.
The content of the invention
It is an object of the invention to provide a kind of microbicide compositions containing ascorbic acid and thifluzamide, can not only expire
The sufficient demand of preventing and treating to rice fungus diseases, and there is very significant effect of increasing production to paddy rice.
The technical scheme is that：
A kind of microbicide compositions containing ascorbic acid and thifluzamide, are prepared from by the raw material of following weight percents：
Ascorbic acid 0.001%~90%, thifluzamide 0.1% -80%, dispersant 1%~15%, cosolvent 0.5%~15%, stabilizer 0%
~5%, solvent 10%~98%, balance of distilled water.
A kind of microbicide compositions containing ascorbic acid and thifluzamide, by the raw material preparation of following weight percents
Into：Ascorbic acid 50%, thifluzamide 20%, dispersant 10%, cosolvent 0.5%, stabilizer 0.1%, solvent 10%, balance of distillation
Water.
A kind of preparation method of the microbicide compositions containing ascorbic acid and thifluzamide, step is as follows：
（1）Stabilizer is stirred, fine powder is pulverized into, 50-100 mesh sieves are crossed, it is standby；
（2）To in stainless steel autoclave, thifluzamide is added, be then slowly added into ascorbic acid and dispersant, airtight heating is extremely
55-75 DEG C, stir 5-9 hours, be subsequently adding distilled water, cosolvent, solvent and step（1）Stabilizer after treatment, keeps temperature
It is 33 DEG C to spend, and continues to stir 35 minutes, obtains mixed solution, standby；
（3）By step（2）Gained mixed solution is lyophilized into powder, encapsulation, obtains final product.
A kind of preparation method of the microbicide compositions containing ascorbic acid and thifluzamide, preferred scheme is, described
Stabilizer is by one or two in sodium alginate, microcrystalline cellulose and converted starch.
A kind of preparation method of the microbicide compositions containing ascorbic acid and thifluzamide, preferred scheme is, described
Dispersant is by one or two in sodium tripolyphosphate and stearic acid list glyceride.
A kind of preparation method of the microbicide compositions containing ascorbic acid and thifluzamide, preferred scheme is, described
Cosolvent be methyl alcohol, propylene glycol monomethyl ether and ethyl acetate in one or two.
A kind of preparation method of the microbicide compositions containing ascorbic acid and thifluzamide, preferred scheme is, described
Solvent is water, alkylbenzene, ester, ketone, glycol, the optional one of alcohol are used as solvent.
A kind of preparation method of the microbicide compositions containing ascorbic acid and thifluzamide, preferred scheme is, step
（1）Cross 80 mesh sieves.
A kind of preparation method of the microbicide compositions containing ascorbic acid and thifluzamide, preferred scheme is, step
（2）Airtight heating is to 65 DEG C.
A kind of preparation method of the microbicide compositions containing ascorbic acid and thifluzamide, preferred scheme is, step
（2）Stirring 7 hours.
Excellent results of the invention are also manifested by：
（1）Preparation is simple for the present composition, green non-pollution, Product quality and safety reliability, easy to use；
（2）Composition has a wide range of application as obtained in the present invention, and significantly, prevention effect is good, has significantly to paddy rice for bactericidal property
The effect of increasing income, with the fabulous prospect of marketing and huge Social benefit and economic benefit.
Specific embodiment
Technical scheme, but protection domain not limited to this are described in detail with reference to embodiment and experimental example.
Embodiment 1：
Formula：Ascorbic acid 0.001kg, thifluzamide 80kg, dispersant 1kg, cosolvent 0.5kg, stabilizer 0.5kg, solvent
10kg, balance of distilled water.
Step is as follows：
（1）Stabilizer sodium alginate is stirred by formula rate, pulverizes into fine powder, cross 50-100 mesh sieves, it is standby；
（2）By formula rate in stainless steel autoclave, thifluzamide is added, be then slowly added into ascorbic acid and dispersant three
Polyphosphate sodium, airtight heating is stirred 5-9 hours to 55-75 DEG C, is subsequently adding distilled water, cosolvent methyl alcohol, solvent alcohol and step
（1）Stabilizer sodium alginate after treatment, keeping temperature is 33 DEG C, continues to stir 35 minutes, obtains mixed solution, standby；
（3）By step（2）Gained mixed solution is lyophilized into powder, encapsulation, obtains final product.
Embodiment 2：Formula：Ascorbic acid 5kg, thifluzamide 20kg, dispersant 10kg, cosolvent 0.5kg, stabilizer
0.1kg, solvent 10kg, balance of distilled water.
A kind of preparation method of above-mentioned microbicide compositions containing ascorbic acid and thifluzamide is：
（1）Stabilizer is stirred, fine powder is pulverized into, 100 mesh sieves are crossed, standby, the stabilizer is by sodium alginate, crystallite
Cellulose and converted starch are 3 according to mass ratio:1:0.1 is formulated；
（2）To in stainless steel autoclave, thifluzamide is added, be then slowly added into ascorbic acid and dispersant, airtight heating is extremely
75 DEG C, stir 9 hours, be subsequently adding distilled water, cosolvent, solvent and step（1）Stabilizer after treatment, keeping temperature is 33
DEG C, continue to stir 35 minutes, obtain mixed solution, it is standby, the dispersant by sodium tripolyphosphate and stearic acid list glyceride according to
Mass ratio is 2.2:0.7 is formulated, and the cosolvent is propylene glycol monomethyl ether and ethyl acetate；
（3）By step（2）Gained mixed solution is lyophilized into powder, encapsulation, obtains final product.
Embodiment 3：Formula：Ascorbic acid 50kg, thifluzamide 10kg, dispersant 1kg, cosolvent 0.5kg, stabilizer
2kg, solvent 10kg, balance of distilled water supplies 100kg.
A kind of preparation method of above-mentioned microbicide compositions containing ascorbic acid and thifluzamide is：
（1）Stabilizer is stirred, fine powder is pulverized into, 80 mesh sieves are crossed, standby, the stabilizer is fine by sodium alginate, crystallite
Dimension element and converted starch are 3 according to mass ratio:1:0.1 is formulated；
（2）To in stainless steel autoclave, thifluzamide is added, be then slowly added into ascorbic acid and dispersant, airtight heating is extremely
65 DEG C, stir 7 hours, be subsequently adding distilled water, cosolvent, solvent and step（1）Stabilizer after treatment, keeping temperature is 33
DEG C, continue to stir 35 minutes, obtain mixed solution, it is standby, the dispersant by sodium tripolyphosphate and stearic acid list glyceride according to
Mass ratio is 2.2:0.7 is formulated, and the cosolvent is propylene glycol monomethyl ether and methyl alcohol；
（3）By step（2）Gained mixed solution is lyophilized into powder, encapsulation, obtains final product.
A kind of test example present invention experimental study of the microbicide compositions containing ascorbic acid and thifluzamide of gained：
1.1 subjects
In 2014, experimental study, for the object application present composition, is carried out with " having mycotic rice test field ".
1.2 experimental designs
1 mu of rice test field is chosen, four trial zones are divided into, is respectively control group（1）And test group（3）, in April 5
Day carries out sterilization at four trial zones.Wherein control group applies Prochloraz and jinggangmeisu intermixture（Purchase in Shandong Province's agriculture
Pharmaceutical factory）, application process：Every mu is watered 40kg by 30g, carries out foliage-spray.Test group applies three embodiments of the invention respectively
Resulting composition, application process：Every mu is watered 40kg by 30g, carries out foliage-spray.
1.3 results and analysis
The influence of control group and test group to rice yield, as shown in table 1.
The control group of table 1 and experimental group paddy rice situation are contrasted
From the data in table 1, it can be seen that growth of the different paddy rice bactericidal effects to paddy rice has differences, wherein present invention gained one kind contains
The microbicide compositions of ascorbic acid and thifluzamide, to the bactericidal effect of paddy rice significantly, yield effect be significantly better than that with it is right
According to group（Paclobutrazol）.It is indicated above that three embodiment resulting compositions of the invention have significant effect of increasing production, paddy rice to peanut
Yield increases 1.034-1.469 kg/hm2Amount of increase in production is 18.93%-26.89%, for effect of increasing production, the embodiment of the present invention
Three gained compounds are to the bactericidal effect of paddy rice, and effect of increasing production is more notable.
It should be pointed out that specific embodiment is the more representational example of the present invention, it is clear that skill of the invention
Art scheme is not limited to above-described embodiment, can also there is many variations.One of ordinary skill in the art, it is clearly public with institute of the invention
Written description open or according to file is undoubted to be obtained, and is considered as this patent scope of the claimed.
Claims (8)
1. a kind of microbicide compositions containing ascorbic acid and thifluzamide, it is characterised in that：By following weight percents
Raw material is prepared from：Ascorbic acid 0.001%~90%, thifluzamide 0.1% -80%, dispersant 1%~15%, cosolvent 0.5%~
15%, stabilizer 0%~5%, solvent 10%~98%, balance of distilled water；
Preparation method, step is as follows：
（1）Stabilizer is stirred, fine powder is pulverized into, 50-100 mesh sieves are crossed, it is standby；
（2）To in stainless steel autoclave, thifluzamide is added, be then slowly added into ascorbic acid and dispersant, airtight heating is extremely
55-75 DEG C, stir 5-9 hours, be subsequently adding distilled water, cosolvent, solvent and step（1）Stabilizer after treatment, keeps temperature
It is 33 DEG C to spend, and continues to stir 35 minutes, obtains mixed solution, standby；
（3）By step（2）Gained mixed solution is lyophilized into powder, encapsulation, obtains final product.
2. a kind of microbicide compositions containing ascorbic acid and thifluzamide according to claim 1, it is characterised in that：
It is prepared from by the raw material of following weight percents：Ascorbic acid 50%, thifluzamide 20%, dispersant 10%, cosolvent
0.5%, stabilizer 0.1%, solvent 10%, balance of distilled water.
3. a kind of microbicide compositions containing ascorbic acid and thifluzamide according to claim 1, it is characterised in that：
Preparation method, preferred scheme is that the stabilizer is by the one kind in sodium alginate, microcrystalline cellulose and converted starch or two
Kind.
4. a kind of microbicide compositions containing ascorbic acid and thifluzamide according to claim 1, it is characterised in that：
Preparation method, preferred scheme is, the dispersant is by one or two in sodium tripolyphosphate and stearic acid list glyceride.
5. a kind of microbicide compositions containing ascorbic acid and thifluzamide according to claim 1, it is characterised in that：
Preparation method, preferred scheme is, the cosolvent is one or two in methyl alcohol, propylene glycol monomethyl ether and ethyl acetate.
6. a kind of microbicide compositions containing ascorbic acid and thifluzamide according to claim 1, it is characterised in that：
Preparation method, preferred scheme is, step（1）Cross 80 mesh sieves.
7. a kind of microbicide compositions containing ascorbic acid and thifluzamide according to claim 1, it is characterised in that：
Preparation method, preferred scheme is, step（2）Airtight heating is to 65 DEG C.
8. a kind of microbicide compositions containing ascorbic acid and thifluzamide according to claim 1, it is characterised in that：
Preparation method, preferred scheme is, step（2）Stirring 7 hours.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611253144.3A CN106852333A (en) | 2016-12-30 | 2016-12-30 | A kind of microbicide compositions containing ascorbic acid and thifluzamide |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611253144.3A CN106852333A (en) | 2016-12-30 | 2016-12-30 | A kind of microbicide compositions containing ascorbic acid and thifluzamide |
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| CN106852333A true CN106852333A (en) | 2017-06-16 |
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| CN201611253144.3A Pending CN106852333A (en) | 2016-12-30 | 2016-12-30 | A kind of microbicide compositions containing ascorbic acid and thifluzamide |
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Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1137344A (en) * | 1995-06-06 | 1996-12-11 | 四川省自然资源研究所 | Composite for regulating transport and distribution of xylophyte substance heeled in or injected in xylem |
| CN101755825A (en) * | 2009-11-23 | 2010-06-30 | 陈章艳 | Bactericide composition containing thifluzamide |
| CN102265837A (en) * | 2011-06-09 | 2011-12-07 | 海利尔药业集团股份有限公司 | Sterilizing composition containing thifluzamide and brassinolide |
| CN103004804A (en) * | 2012-11-26 | 2013-04-03 | 安徽农业大学 | Thifluzamide oil suspension and use and preparation method thereof |
| CN104981161A (en) * | 2012-11-19 | 2015-10-14 | 拱门木材保护有限公司 | Succinate dehydrogenase inhibitor containing compositions |
-
2016
- 2016-12-30 CN CN201611253144.3A patent/CN106852333A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1137344A (en) * | 1995-06-06 | 1996-12-11 | 四川省自然资源研究所 | Composite for regulating transport and distribution of xylophyte substance heeled in or injected in xylem |
| CN101755825A (en) * | 2009-11-23 | 2010-06-30 | 陈章艳 | Bactericide composition containing thifluzamide |
| CN102265837A (en) * | 2011-06-09 | 2011-12-07 | 海利尔药业集团股份有限公司 | Sterilizing composition containing thifluzamide and brassinolide |
| CN104981161A (en) * | 2012-11-19 | 2015-10-14 | 拱门木材保护有限公司 | Succinate dehydrogenase inhibitor containing compositions |
| CN103004804A (en) * | 2012-11-26 | 2013-04-03 | 安徽农业大学 | Thifluzamide oil suspension and use and preparation method thereof |
Non-Patent Citations (2)
| Title |
|---|
| 严凯 等: "葡萄霜霉病的田间调查及防治效果研究", 《农业研究与应用》 * |
| 黄荣茂 等: "抗病丰（6%抗坏血酸水剂）对水稻增产效果研究", 《农药》 * |
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| SE01 | Entry into force of request for substantive examination | ||
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Application publication date: 20170616 |
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