CN106833927A - Medical scope biomembrane remover and preparation method thereof - Google Patents
Medical scope biomembrane remover and preparation method thereof Download PDFInfo
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- CN106833927A CN106833927A CN201611127901.2A CN201611127901A CN106833927A CN 106833927 A CN106833927 A CN 106833927A CN 201611127901 A CN201611127901 A CN 201611127901A CN 106833927 A CN106833927 A CN 106833927A
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- biomembrane
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- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
- C11D1/66—Non-ionic compounds
- C11D1/83—Mixtures of non-ionic with anionic compounds
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/02—Inorganic compounds ; Elemental compounds
- C11D3/04—Water-soluble compounds
- C11D3/06—Phosphates, including polyphosphates
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/20—Organic compounds containing oxygen
- C11D3/2003—Alcohols; Phenols
- C11D3/2041—Dihydric alcohols
- C11D3/2044—Dihydric alcohols linear
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/20—Organic compounds containing oxygen
- C11D3/2075—Carboxylic acids-salts thereof
- C11D3/2079—Monocarboxylic acids-salts thereof
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/20—Organic compounds containing oxygen
- C11D3/2075—Carboxylic acids-salts thereof
- C11D3/2086—Hydroxy carboxylic acids-salts thereof
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/26—Organic compounds containing nitrogen
- C11D3/28—Heterocyclic compounds containing nitrogen in the ring
-
- C—CHEMISTRY; METALLURGY
- C23—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; CHEMICAL SURFACE TREATMENT; DIFFUSION TREATMENT OF METALLIC MATERIAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL
- C23G—CLEANING OR DE-GREASING OF METALLIC MATERIAL BY CHEMICAL METHODS OTHER THAN ELECTROLYSIS
- C23G1/00—Cleaning or pickling metallic material with solutions or molten salts
- C23G1/02—Cleaning or pickling metallic material with solutions or molten salts with acid solutions
- C23G1/04—Cleaning or pickling metallic material with solutions or molten salts with acid solutions using inhibitors
- C23G1/06—Cleaning or pickling metallic material with solutions or molten salts with acid solutions using inhibitors organic inhibitors
- C23G1/068—Cleaning or pickling metallic material with solutions or molten salts with acid solutions using inhibitors organic inhibitors compounds containing a C=C bond
-
- C—CHEMISTRY; METALLURGY
- C23—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; CHEMICAL SURFACE TREATMENT; DIFFUSION TREATMENT OF METALLIC MATERIAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL
- C23G—CLEANING OR DE-GREASING OF METALLIC MATERIAL BY CHEMICAL METHODS OTHER THAN ELECTROLYSIS
- C23G1/00—Cleaning or pickling metallic material with solutions or molten salts
- C23G1/02—Cleaning or pickling metallic material with solutions or molten salts with acid solutions
- C23G1/10—Other heavy metals
- C23G1/103—Other heavy metals copper or alloys of copper
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
- C11D1/66—Non-ionic compounds
- C11D1/667—Neutral esters, e.g. sorbitan esters
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- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Emergency Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Materials Engineering (AREA)
- Mechanical Engineering (AREA)
- Metallurgy (AREA)
- Inorganic Chemistry (AREA)
- Detergent Compositions (AREA)
Abstract
The invention belongs to medical cleaning supplies technical field, and in particular to a kind of medical scope biomembrane remover and preparation method thereof.Medical scope is made up with biomembrane remover of the following raw material：Sodium tripolyphosphate, sodium citrate, 1.2 propane diols, polysorbas20, sorbic acid, RQ 129E, Mirataine ASC, TTA, distilled water.Quick thoroughly removal biomembrane of the invention；Foam volume is low, is adapted to hand washing and machine-washes；Can reuse, with continued biological film removal effect；It is corrosion-free for scope material, extend scope service life.
Description
Technical field
The invention belongs to medical cleaning supplies technical field, and in particular to a kind of medical scope with biomembrane remover and its
Preparation method.
Background technology
In medical field, scope biomembrane is one of the major reason for causing nosocomialtion.Bacterial biof iotalm
(bacterial bio-film, BF) is the Extracellular polymers matrix (extracellular secreted by bacterium and its bacterium itself
Polymericsubstance, EPS) constituted, and it is irreversible adhere to abiotic or biological surface, it protect bacterium exempt from
In protected from environmental and increase repellence of the bacterium to bactericide.The resistance of bacterium is strong compared with planktonic bacteria by 1000 in biomembrane
Times.Research finds that the formation of biomembrane can significantly reduce the effect of disinfectant.Scope is used as a kind of invasive, the diagnosis and treatment of minimal invasive
Instrument is widely used to clinic, but due to its complex structure, material majority non-refractories, perishable, to using rear scope
Cleaning, sterilization, sterilization zone come difficult, thus are more likely formed biomembrane.Research finds bacterial biof iotalm endoscope after sterilization
Generally existing in tube chamber, this plays an important role in the infections relating caused by scope.The presence of bacterial biof iotalm, causes
The thorough disinfection failure that scope should reach, causes that cross-infection occurs between patient, increased the death rate and payment for medical care of patient
With, as the potential important factor in order of hospital infection, because of the correct selection of cleaning agent in clinical endoscopic reprocessing and use, be
The theoretical foundation of the removing offer science of biomembrane in clinical endoscopic reprocessing, so as to better control over cross-infection, it is ensured that doctor
Safety is treated, it is significant.
Documents and materials show that the conventional neutral multienzyme cleaning agent of present medical institutions and alkaline multienzyme cleaning agent are for albumen
The common surgical apparatus contamination thing such as matter and fat is respectively provided with good cleaning performance, but for biomembrane removal effect compared with
Difference.And strong alkali solution is preferable for the removal effect of biomembrane, but there is great aging effect for the material of scope
And corrosivity.
The content of the invention
It is an object of the invention to provide a kind of medical scope biomembrane remover, scope biomembrane can be effectively removed,
And, foam volume low for the corrosivity of scope is low；Invention also provides the preparation of biomembrane remover of medical scope
Method, it is scientific and reasonable, simple and easy to apply.
Medical scope biomembrane remover of the present invention, is made up of the raw material of following parts by weight：
It is pure that described sodium tripolyphosphate, sodium citrate, polysorbas20, sorbic acid and TTA are analysis.
1.2 described propane diols are 1.2 propane diols of the concentration of DOW Chemical 99%.
Described RQ-129E is the surfactant of Shenzhen Rong Qiang productions, substance content more than 95%.
Described Mirataine ASC are the surfactant of the sub- production in sieve ground, and effective content is more than 90%.
Electrical conductivity≤15 μ the s/cm of described distilled water.
The medical scope of the present invention preparation method of biomembrane remover, step is as follows：
(1) by distilled water add reaction vessel in, turn on agitator, then by sodium tripolyphosphate, sodium citrate, TTA, mountain
Pears acid is sequentially added, and is stirred continuously until whole dissolvings, obtains liquid；Often adding a kind of solid material need to continue 30 points of stirring
Zhong Hou, can add down a kind of raw material；
(2) liquid that step (1) is obtained is filtered using double-layer filter cloth, is obtained solution；
(3) 1.2- propane diols, polysorbas20, RQ-129E are sequentially added in the solution for obtaining to step (2), and continues stirring；
(4) to addition Mirataine ASC in reaction vessel, and continue stirring, obtain final product.
The mesh number of the filter cloth described in step (2) is 400 mesh.
Mixing time described in step (3) is 60min.
Mixing time described in step (4) is 30min.
Biomembrane remover involved in the present invention is applied to the biological Membrane cleaning removal of medical scope inwall.Due to scope knot
Structure is complicated, material majority non-refractories, perishable, difficult to the cleaning using rear scope, sterilization, sterilization zone, thus is more easy to
Form biomembrane.And the presence of biomembrane can cause scope cannot sterilization it is qualified, so as to produce the wind of cross-patient contamination
Danger.Although the effect of conventional multienzyme cleaning agent for medical purpose and alkaline multienzyme cleaning agent with good removal blood stains, for
The cleansing power of biomembrane is poor, and almost without removal effect, and corrosivity is stronger.Therefore, in such cleaning agent is not suitable for
The cleaning removal of mirror biomembrane.Sodium tripolyphosphate in cleaning agent of the present invention not only provides enough alkaline matters to formula,
And itself just has good clean effect, is first bright spot of this formula while having excellent corrosion mitigating effect；
1.2- propane diols can improve remover wetting speed in itself, while improve the stability of product；With the addition of surface-active
Agent RQ-129E and Mirataine ASC, both are low foaming surfactant, and RQ-129E has good permeability and decontamination
Power, the foam of Mirataine ASC is extremely low and wettability is excellent, and it is right that the addition of two kinds of surfactants improves the present invention
In the permeance property of biomembrane, so as to reach rapid osmotic, the effect of wetting；Sorbic acid, can used as preservative of the invention
Stability is improved in the presence of polysorbas20；Because the annex of scope is frequently used copper and copper alloy is made, in order to
Corrosion of the cleaning agent for copper material is reduced, TTA is with the addition of as corrosion inhibiter in the present invention.
The present invention compared with prior art, has the advantages that：
1st, quick thoroughly removal biomembrane；
2nd, foam volume is low, is adapted to hand washing and machine-washes；
3rd, can reuse, with continued biological film removal effect；
4th, it is corrosion-free for scope material, extend scope service life.
Specific embodiment
The present invention is described further with reference to embodiments.
Embodiment 1
Preparation method is as follows：
(1) by distilled water add reaction vessel in, turn on agitator, then by sodium tripolyphosphate, sodium citrate, TTA, mountain
Pears acid is sequentially added, and is stirred continuously until whole dissolvings, obtains liquid；Often adding a kind of solid material need to continue 30 points of stirring
Zhong Hou, can add down a kind of raw material；
(2) liquid for obtaining step (1) is filtered using double-deck 400 mesh filter cloth, obtains solution；
(3) 1.2- propane diols, polysorbas20, RQ-129E are sequentially added in the solution for obtaining to step (2), and continues stirring
60min；
(4) to addition Mirataine ASC in reaction vessel, and continue to stir 30min, obtain final product.
Embodiment 2
Preparation method is with embodiment 1.
Embodiment 3
Preparation method is with embodiment 1.
Embodiment 4
Preparation method is with embodiment 1.
Claims (10)
1. a kind of medical scope biomembrane remover, it is characterised in that be made up of the raw material of following parts by weight：
2. medical scope biomembrane remover according to claim 1, it is characterised in that described sodium tripolyphosphate, lemon
It is pure that lemon acid sodium, polysorbas20, sorbic acid and TTA are analysis.
3. medical scope biomembrane remover according to claim 1, it is characterised in that 1.2 described propane diols are pottery
1.2 propane diols of family name's 99% concentration of chemistry.
4. medical scope biomembrane remover according to claim 1, it is characterised in that described RQ-129E is Shenzhen
The surfactant of Rong Qiang productions, substance content more than 95%.
5. medical scope biomembrane remover according to claim 1, it is characterised in that described Mirataine ASC
It is the surfactant of the sub- production in sieve ground, effective content is more than 90%.
6. medical scope biomembrane remover according to claim 1, it is characterised in that the conductance of described distilled water
Rate≤15 μ s/cm.
7. a kind of claim 1-6 any described medical scopes preparation method of biomembrane remover, it is characterised in that step
It is rapid as follows：
(1) by distilled water add reaction vessel in, turn on agitator, then by sodium tripolyphosphate, sodium citrate, TTA, sorbic acid
Sequentially add, and be stirred continuously until whole dissolvings, obtain liquid；Often adding a kind of solid material need to continue stirring 30 minutes
Afterwards, a kind of raw material can be added down；
(2) liquid that step (1) is obtained is filtered using double-layer filter cloth, is obtained solution；
(3) 1.2- propane diols, polysorbas20, RQ-129E are sequentially added in the solution for obtaining to step (2), and continues stirring；
(4) to addition Mirataine ASC in reaction vessel, and continue stirring, obtain final product.
8. the medical scope according to claim 7 preparation method of biomembrane remover, it is characterised in that in step (2)
The mesh number of described filter cloth is 400 mesh.
9. the medical scope according to claim 7 preparation method of biomembrane remover, it is characterised in that in step (3)
Described mixing time is 60min.
10. the medical scope according to claim 7 preparation method of biomembrane remover, it is characterised in that step (4)
Described in mixing time be 30min.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611127901.2A CN106833927A (en) | 2016-12-09 | 2016-12-09 | Medical scope biomembrane remover and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611127901.2A CN106833927A (en) | 2016-12-09 | 2016-12-09 | Medical scope biomembrane remover and preparation method thereof |
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| Publication Number | Publication Date |
|---|---|
| CN106833927A true CN106833927A (en) | 2017-06-13 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201611127901.2A Pending CN106833927A (en) | 2016-12-09 | 2016-12-09 | Medical scope biomembrane remover and preparation method thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109022169A (en) * | 2018-05-21 | 2018-12-18 | 苏州佑君环境科技有限公司 | A kind of chemiluminescence instrument pipeline composite cleaning liquid and preparation method thereof |
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| CN102071113A (en) * | 2011-02-05 | 2011-05-25 | 徐宏汇 | Condensed multi-enzyme medical cleaning agent |
| CN102294056A (en) * | 2011-09-02 | 2011-12-28 | 山东新华医疗器械股份有限公司 | Surgical instrument moisturizing agent and preparation method thereof |
| CN102329696A (en) * | 2011-09-02 | 2012-01-25 | 山东新华医疗器械股份有限公司 | Basic enzyme-containing detergent and preparation method thereof |
| CN102329699A (en) * | 2011-09-02 | 2012-01-25 | 山东新华医疗器械股份有限公司 | Alkaline cleaning agent and preparation method thereof |
-
2016
- 2016-12-09 CN CN201611127901.2A patent/CN106833927A/en active Pending
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1880423A (en) * | 2006-05-17 | 2006-12-20 | 山东新华医疗器械股份有限公司 | Low foaming surfactant for cleaning and method for preparing same |
| CN101809134A (en) * | 2007-08-03 | 2010-08-18 | 美国消毒者公司 | Biodegradable detergent concentrate for medical instruments and equipment |
| CN102010802A (en) * | 2010-12-13 | 2011-04-13 | 陈继峰 | Concentrated multienzyme cleaning solution and preparation method thereof |
| CN102071113A (en) * | 2011-02-05 | 2011-05-25 | 徐宏汇 | Condensed multi-enzyme medical cleaning agent |
| CN102294056A (en) * | 2011-09-02 | 2011-12-28 | 山东新华医疗器械股份有限公司 | Surgical instrument moisturizing agent and preparation method thereof |
| CN102329696A (en) * | 2011-09-02 | 2012-01-25 | 山东新华医疗器械股份有限公司 | Basic enzyme-containing detergent and preparation method thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109022169A (en) * | 2018-05-21 | 2018-12-18 | 苏州佑君环境科技有限公司 | A kind of chemiluminescence instrument pipeline composite cleaning liquid and preparation method thereof |
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Application publication date: 20170613 |