CN102329696A - Basic enzyme-containing detergent and preparation method thereof - Google Patents
Basic enzyme-containing detergent and preparation method thereof Download PDFInfo
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- CN102329696A CN102329696A CN 201110257701 CN201110257701A CN102329696A CN 102329696 A CN102329696 A CN 102329696A CN 201110257701 CN201110257701 CN 201110257701 CN 201110257701 A CN201110257701 A CN 201110257701A CN 102329696 A CN102329696 A CN 102329696A
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Abstract
The invention belongs to the technical field of medical detergent, and relates to a basic enzyme-containing detergent and a preparation method thereof. The basic enzyme-containing detergent is composed of the following components in percentage by mass: 70-84% of water, 2-10% of inorganic base, 0.5-2% of surfactant, 10-24% of corrosion inhibitor, 2-5% of chelating agent and 1-4% of protease. The basic enzyme-containing detergent has the characteristics that the protease added in the basic enzyme-containing detergent can decompose fat and has good protein removal effect in alkalescent environment, thus the cleaning effect is improved; and the basic enzyme-containing detergent has the advantages of no corrosion, low foam amount, high wettability, low cost, high safety and good cleaning effect. The preparation method of the basic enzyme-containing detergent is simple and feasible, and is easy to implement and control.
Description
Technical field
The invention belongs to medical washing composition technical field, relate to a kind of alkalescence and contain enzyme clean-out system and preparation method thereof.
Background technology
It is neutral multienzyme cleaning agent that present domestic hospital supply room cleans instruments sanitising agent commonly used, and this product can clean the instruments and the article of all materials, but owing to added multiple enzyme, so expensive, a lot of hospitals can only hang back.In addition, find through the actual investigation to how tame hospital: conventional instruments 95% is a stainless steel, and the apparatus that cleans stainless steel can use the sanitising agent of alkalescence fully.Though and simple alkaline matter has good decomposition effect for fat.If but make it also have the decomposition effect to protein, just must improve the pH value of sanitising agent, and the too high meeting of pH value produces corrosion to apparatus.In order to address this problem; Can under the condition of low alkali, in system, add Sumizyme MP, clean-out system not only can be reduced fat, for protein good effect of removing arranged also simultaneously; Improve the whole cleansing power of product, reduced cost simultaneously.
Summary of the invention
The purpose of this invention is to provide a kind of alkalescence and contain the enzyme clean-out system; Under the condition of low alkali, in system, add Sumizyme MP; Clean-out system not only can be reduced fat; Simultaneously for protein good effect of removing is arranged also, have that no burn into foam volume is low, high wettability, low cost, safety, a advantage that cleaning performance is good, the present invention provides simple preparation method simultaneously.
Alkalescence of the present invention contains the enzyme clean-out system, and the quality percentage composition of its batching is following:
Described water is zero(ppm) water, mass percent preferred 80%.
Described mineral alkali is yellow soda ash, salt of wormwood or sodium hydrogencarbonate, mass percent preferred 5%.
Described tensio-active agent is AEO-9 and/or polysorbas20, mass percent preferred 1%.
Described inhibiter is one or more in trolamine, Sodium Nitrite or the water glass, mass percent preferred 15%.
Described sequestrant is Trisodium Citrate or EDTA-4Na, mass percent preferred 3%.
Described proteolytic enzyme is liquid basified protease, and mass percent is preferred 2%, the product of preferred Novozymes Company, and model is Alcalase.
Described alkalescence contains the preparation method of enzyme clean-out system: earlier water is joined in the container, add tensio-active agent, mineral alkali, inhibiter, sequestrant and proteolytic enzyme more successively and mix, after stirring and dissolving, filtration makes.
Described stirring velocity is 150～200 rev/mins; Described solvent temperature is 15 ℃～30 ℃; Described filtering net adopts double-deck 200 purpose filtering nets.
The raw material that described tensio-active agent, mineral alkali, inhibiter and sequestrant are used is all selected analytical pure for use.
Beneficial effect of the present invention is following:
Alkalescence of the present invention contains the enzyme clean-out system to be weakly alkaline and to have added inhibiter, can remove various organic dirt on apparatus surface fast, does not therefore have corrosion for stainless steel instruments; Foam volume is low, under mechanical cleaning condition, can not produce excess foam; High wettability; Make its can quick humidification, the various dirts of emulsification, the proteolytic enzyme of interpolation can not only reduce fat under weakly alkaline environment, and protein is also had good effect of removing; Improved cleaning performance; Clean-out system of the present invention has prolonged the work-ing life of equipment, apparatus, has guaranteed the health of human body, and manual, the machinery that can be used for the stainless steel instruments clean; Its preparation method is simple.
Embodiment
Below in conjunction with embodiment the present invention is done and to further describe.
The raw material that tensio-active agent described in the embodiment, alkali, inhibiter and sequestrant are used is all selected analytical pure for use, and Sumizyme MP is the product of Novozymes Company, and model is Alcalase.
Embodiment 1
Embodiment 1 each component formula sees Table 1.
Table 1 embodiment 1 each component formula table
| Component | Mass percent (%) |
| Zero(ppm) water | 78 |
| Yellow soda ash | 7 |
| Trolamine | 10 |
| AEO-9 | 0.8 |
| Trisodium Citrate | 2.2 |
| Sumizyme MP | 2 |
Described alkalescence contains the preparation method of enzyme clean-out system: earlier zero(ppm) water is joined in the container, add AEO-9, yellow soda ash, trolamine, Trisodium Citrate and Sumizyme MP more successively and mix, after stirring and dissolving, filtration makes; Reinforced principle adds that the back is a kind of before being after a kind of dissolving again, and stirring velocity is 160 ± 5 rev/mins, and solvent temperature is 15 ℃, and filtering net adopts double-deck 200 purpose filtering nets.
The alkalescence of embodiment 1 preparation contains enzyme clean-out system clear is not had deposition, faint yellow, has no irritating odor good stability.Blood stains for instruments have good effect of removing; Through its pH value of test is 9.10, and foam volume (pressing the test of Luo Shi Latherometer) for 65ml, does not have corrosion for 304 stainless steel substrates.
Embodiment 2
Embodiment 2 each component formula see Table 2.
Table 2 embodiment 2 each component formula table
| Component | Mass percent (%) |
| Zero(ppm) water | 75 |
| Yellow soda ash | 4 |
| Sodium hydrogencarbonate | 3 |
| Trolamine | 13 |
| AEO-9 | 1 |
| Trisodium Citrate | 2 |
| Sumizyme MP | 2 |
Described alkalescence contains the preparation method of enzyme clean-out system: earlier zero(ppm) water is joined in the container, add AEO-9, yellow soda ash, sodium hydrogencarbonate, trolamine, Trisodium Citrate and Sumizyme MP more successively and mix, after stirring and dissolving, filtration makes; Reinforced principle adds that the back is a kind of before being after a kind of dissolving again, and stirring velocity is 160 ± 5 rev/mins, and solvent temperature is 20 ℃, and filtering net adopts double-deck 200 purpose filtering nets.
The alkalescence of embodiment 2 preparations contains enzyme clean-out system clear is not had deposition, faint yellow, has no irritating odor good stability.Blood stains for instruments have good effect of removing; Through its pH value of test is 8.9, and foam volume (pressing the test of Luo Shi Latherometer) for 70ml, does not have corrosion for 304 stainless steel substrates.
Embodiment 3
Embodiment 3 each component formula see Table 3.
Table 3 embodiment 3 each component formula table
| Component | Mass percent (%) |
| Zero(ppm) water | 84 |
| Yellow soda ash | 2.5 |
| Trolamine | 10 |
| Polysorbas20 | 0.5 |
| Trisodium Citrate | 1 |
| EDTA-4Na | 1 |
| Sumizyme MP | 1 |
Described alkalescence contains the preparation method of enzyme clean-out system: earlier zero(ppm) water is joined in the container, add polysorbas20, yellow soda ash, trolamine, Trisodium Citrate, EDTA-4Na and Sumizyme MP more successively and mix, after stirring and dissolving, filtration makes; Reinforced principle adds that the back is a kind of before being after a kind of dissolving again, and stirring velocity is 160 ± 5 rev/mins, and solvent temperature is 25 ℃, and filtering net adopts double-deck 200 purpose filtering nets.
The alkalescence of embodiment 3 preparations contains enzyme clean-out system clear is not had deposition, faint yellow, has no irritating odor good stability.Blood stains for instruments have good effect of removing; Through its pH value of test is 8.5, and foam volume (pressing the test of Luo Shi Latherometer) for 59ml, does not have corrosion for 304 stainless steel substrates.
Embodiment 4
Embodiment 4 each component formula see Table 4.
Table 4 embodiment 4 each component formula table
| Component | Mass percent (%) |
| Zero(ppm) water | 75 |
| Yellow soda ash | 4 |
| Sodium hydrogencarbonate | 2 |
| Salt of wormwood | 1 |
| Trolamine | 7 |
| Sodium Nitrite | 2 |
| Water glass | 2 |
| AEO-9 | 1 |
| EDTA-4Na | 4 |
| Sumizyme MP | 2 |
Described alkalescence contains the preparation method of enzyme clean-out system: earlier zero(ppm) water is joined in the container; Adding AEO-9, yellow soda ash, sodium hydrogencarbonate, salt of wormwood, trolamine, Sodium Nitrite, water glass, EDTA-4Na and Sumizyme MP more successively mixes; After stirring and dissolving, filtration makes; Reinforced principle adds that the back is a kind of before being after a kind of dissolving again, and stirring velocity is 180 ± 5 rev/mins, and solvent temperature is 20 ℃, and filtering net adopts double-deck 200 purpose filtering nets.
The alkalescence of embodiment 4 preparations contains enzyme clean-out system clear is not had deposition, faint yellow, has no irritating odor good stability.Blood stains for instruments have good effect of removing; Through its pH value of test is 9.0, and foam volume (pressing the test of Luo Shi Latherometer) for 70ml, does not have corrosion for 304 stainless steel substrates.
Embodiment 5
Embodiment 5 each component formula see Table 5.
Table 5 embodiment 5 each component formula table
| Component | Mass percent (%) |
| Zero(ppm) water | 75 |
| Yellow soda ash | 5 |
| Sodium hydrogencarbonate | 2 |
| Trolamine | 10 |
| Sodium Nitrite | 2 |
| AEO-9 | 0.5 |
| EDTA-4Na | 3.5 |
| Sumizyme MP | 2 |
Described alkalescence contains the preparation method of enzyme clean-out system: earlier zero(ppm) water is joined in the container; Adding AEO-9, yellow soda ash, sodium hydrogencarbonate, trolamine, Sodium Nitrite, EDTA-4Na and Sumizyme MP more successively mixes; After stirring and dissolving, filtration makes; Reinforced principle adds that the back is a kind of before being after a kind of dissolving again, and stirring velocity is 160 ± 5 rev/mins, and solvent temperature is 30 ℃, and filtering net adopts double-deck 200 purpose filtering nets.
The alkalescence of embodiment 5 preparations contains enzyme clean-out system clear is not had deposition, faint yellow, has no irritating odor good stability.Blood stains for instruments have good effect of removing; Through its pH value of test is 9.0, and foam volume (pressing the test of Luo Shi Latherometer) for 62ml, does not have corrosion for 304 stainless steel substrates.
Embodiment 6
Embodiment 6 each component formula see Table 6.
Table 6 embodiment 6 each component formula table
| Component | Mass percent (%) |
| Zero(ppm) water | 75 |
| Yellow soda ash | 4 |
| Sodium hydrogencarbonate | 2 |
| Salt of wormwood | 1 |
| Water glass | 7 |
| Sodium Nitrite | 4 |
| AEO-9 | 1 |
| EDTA-4Na | 4 |
| Sumizyme MP | 2 |
Described alkalescence contains the preparation method of enzyme clean-out system: earlier zero(ppm) water is joined in the container; Adding AEO-9, yellow soda ash, sodium hydrogencarbonate, salt of wormwood, Sodium Nitrite, water glass, EDTA-4Na and Sumizyme MP more successively mixes; After stirring and dissolving, filtration makes; Reinforced principle adds that the back is a kind of before being after a kind of dissolving again, and stirring velocity is 180 ± 5 rev/mins, and solvent temperature is 20 ℃, and filtering net adopts double-deck 200 purpose filtering nets.
The alkalescence of embodiment 6 preparations contains enzyme clean-out system clear is not had deposition, faint yellow, has no irritating odor good stability.Blood stains for instruments have good effect of removing; Through its pH value of test is 9.3, and foam volume (pressing the test of Luo Shi Latherometer) for 67ml, does not have corrosion for 304 stainless steel substrates.
Claims (10)
1. an alkalescence contains the enzyme clean-out system, it is characterized in that the quality percentage composition of its batching is following:
2. alkalescence according to claim 1 contains the enzyme clean-out system, it is characterized in that described water is zero(ppm) water.
3. alkalescence according to claim 1 contains the enzyme clean-out system, it is characterized in that described mineral alkali is yellow soda ash, salt of wormwood or sodium hydrogencarbonate.
4. alkalescence according to claim 1 contains the enzyme clean-out system, it is characterized in that described tensio-active agent is AEO-9 and/or polysorbas20.
5. alkalescence according to claim 1 contains the enzyme clean-out system, it is characterized in that described inhibiter is one or more in trolamine, Sodium Nitrite or the water glass.
6. alkalescence according to claim 1 contains the enzyme clean-out system, it is characterized in that described sequestrant is Trisodium Citrate or EDTA-4Na.
7. alkalescence according to claim 1 contains the enzyme clean-out system, it is characterized in that described proteolytic enzyme is liquid basified protease.
8. the arbitrary described alkalescence of claim 1～7 contains the preparation method of enzyme clean-out system; It is characterized in that earlier water being joined in the container; Add tensio-active agent, mineral alkali, inhibiter, sequestrant and proteolytic enzyme more successively and mix, after stirring and dissolving, filtration makes.
9. alkalescence according to claim 8 contains the preparation method of enzyme clean-out system, it is characterized in that described stirring velocity is 150～200 rev/mins, and described solvent temperature is 15 ℃～30 ℃.
10. alkalescence according to claim 8 contains the preparation method of enzyme clean-out system, it is characterized in that described filtering net adopts double-deck 200 purpose filtering nets.
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| CN 201110257701 CN102329696A (en) | 2011-09-02 | 2011-09-02 | Basic enzyme-containing detergent and preparation method thereof |
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| CN 201110257701 CN102329696A (en) | 2011-09-02 | 2011-09-02 | Basic enzyme-containing detergent and preparation method thereof |
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Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103756815A (en) * | 2013-12-23 | 2014-04-30 | 李艳妮 | Enzyme-containing cleaning agent used for food and beverage industry and composition and preparation method thereof |
| CN106281761A (en) * | 2016-08-19 | 2017-01-04 | 南京巨鲨显示科技有限公司 | A kind of medical apparatus and instruments multienzyme cleaning agent and preparation method thereof |
| CN106833927A (en) * | 2016-12-09 | 2017-06-13 | 山东新华医疗器械股份有限公司 | Medical scope biomembrane remover and preparation method thereof |
| CN106947614A (en) * | 2017-03-22 | 2017-07-14 | 安徽民泰医药科技有限公司 | Blood cell analysis cleaning fluid |
| CN107828538A (en) * | 2017-11-29 | 2018-03-23 | 鹿寨卡森洗涤服务有限公司 | Net white concentrated type cloth grass detergent |
| CN108130195A (en) * | 2017-12-27 | 2018-06-08 | 北京欧美中科学技术研究院 | A kind of military strength alkalinity complex cleaning and washing agent and preparation method thereof |
| CN110982635A (en) * | 2019-12-26 | 2020-04-10 | 南京奇点生物科技有限公司 | Efficient enzyme-containing cleaning solution and preparation method thereof |
| CN111073768A (en) * | 2019-12-15 | 2020-04-28 | 华中科技大学同济医学院附属协和医院 | Medical sol and preparation method thereof |
| CN115537821A (en) * | 2022-09-01 | 2022-12-30 | 深圳市豪龙新材料技术有限公司 | Bio-enzyme detergent for metal surface and preparation method thereof |
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| CN1056904A (en) * | 1990-05-30 | 1991-12-11 | 李洪耀 | High efficiency clening agent for engine of vehicle |
| CN1813052A (en) * | 2003-07-02 | 2006-08-02 | 埃科莱布有限公司 | Warewashing composition for use in automatic dishwashing machines, and methods for manufacturing and using |
| CN101748001A (en) * | 2008-12-16 | 2010-06-23 | 中国药品生物制品检定所 | Washing agent special for labs |
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Patent Citations (3)
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| CN1056904A (en) * | 1990-05-30 | 1991-12-11 | 李洪耀 | High efficiency clening agent for engine of vehicle |
| CN1813052A (en) * | 2003-07-02 | 2006-08-02 | 埃科莱布有限公司 | Warewashing composition for use in automatic dishwashing machines, and methods for manufacturing and using |
| CN101748001A (en) * | 2008-12-16 | 2010-06-23 | 中国药品生物制品检定所 | Washing agent special for labs |
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103756815A (en) * | 2013-12-23 | 2014-04-30 | 李艳妮 | Enzyme-containing cleaning agent used for food and beverage industry and composition and preparation method thereof |
| CN103756815B (en) * | 2013-12-23 | 2015-08-12 | 李艳妮 | Containing food_beverage industry sanitising agent and composition, the preparation method of enzyme |
| CN106281761A (en) * | 2016-08-19 | 2017-01-04 | 南京巨鲨显示科技有限公司 | A kind of medical apparatus and instruments multienzyme cleaning agent and preparation method thereof |
| CN106833927A (en) * | 2016-12-09 | 2017-06-13 | 山东新华医疗器械股份有限公司 | Medical scope biomembrane remover and preparation method thereof |
| CN106947614A (en) * | 2017-03-22 | 2017-07-14 | 安徽民泰医药科技有限公司 | Blood cell analysis cleaning fluid |
| CN107828538A (en) * | 2017-11-29 | 2018-03-23 | 鹿寨卡森洗涤服务有限公司 | Net white concentrated type cloth grass detergent |
| CN108130195A (en) * | 2017-12-27 | 2018-06-08 | 北京欧美中科学技术研究院 | A kind of military strength alkalinity complex cleaning and washing agent and preparation method thereof |
| CN111073768A (en) * | 2019-12-15 | 2020-04-28 | 华中科技大学同济医学院附属协和医院 | Medical sol and preparation method thereof |
| CN111073768B (en) * | 2019-12-15 | 2021-05-14 | 华中科技大学同济医学院附属协和医院 | Medical sol and preparation method thereof |
| CN110982635A (en) * | 2019-12-26 | 2020-04-10 | 南京奇点生物科技有限公司 | Efficient enzyme-containing cleaning solution and preparation method thereof |
| CN115537821A (en) * | 2022-09-01 | 2022-12-30 | 深圳市豪龙新材料技术有限公司 | Bio-enzyme detergent for metal surface and preparation method thereof |
| CN115537821B (en) * | 2022-09-01 | 2023-10-27 | 深圳市豪龙新材料技术有限公司 | Biological enzyme detergent for metal surface and preparation method thereof |
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Application publication date: 20120125 |