CN106798909A - A kind of Chinese patent drug and its preparation technology for tonifying the liver and kidney - Google Patents
A kind of Chinese patent drug and its preparation technology for tonifying the liver and kidney Download PDFInfo
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- 238000002360 preparation method Methods 0.000 title claims abstract description 17
- 238000005516 engineering process Methods 0.000 title claims abstract description 7
- 210000000582 semen Anatomy 0.000 claims abstract description 14
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/11—Pteridophyta or Filicophyta (ferns)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K36/17—Gnetophyta, e.g. Ephedraceae (Mormon-tea family)
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
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- A61K2236/30—Extraction of the material
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Abstract
The invention discloses a kind of Chinese patent drug for tonifying the liver and kidney and its preparation technology.Described Chinese patent drug is mainly made up of the Chinese medicine of following mass parts：60~100 parts of cultivated land, 60~100 parts of raw ephedra, 60~100 parts of semen brassicae, 60~100 parts of baked ginger, 60~100 parts of the bark of eucommia, 60~100 parts of rhizoma cibotii, 60~100 parts of Chinese cassia tree, 60~100 parts of Semen Cuscutae, 60~100 parts of the root of bidentate achyranthes, 60~100 parts of dipsacus root, 60~100 parts of luffa adds proper auxiliary materials to be made 1000 parts after extraction.Of the invention for the Chinese patent drug reasonable recipe that tonifies the liver and kidney, flavour of a drug are fewer but better, and each medicine produces synergy, can produce good effect tonified the liver and kidney for treatment.
Description
Technical field
The invention belongs to technical field of traditional Chinese medicines, and in particular to a kind of Chinese patent drug for tonifying the liver and kidney and its preparation technology.
Background technology
It is all to play the role of help energy and blood of human body negative and positive deficiency, various asthenic symptoms can be treated, strengthen people's constitution, improve resistance against diseases
Medicine, referred to as tonic.Can be divided into, tonifying Qi side's medicine, the side's of enriching blood medicine, tonifying yin side's medicine and the class of yang-tonifying side's medicine four.
Meaning
It is all to play the role of help energy and blood of human body negative and positive deficiency, various asthenic symptoms can be treated, strengthen people's constitution, improve the medicine of resistance against diseases
Thing, referred to as tonic.
Principle legislation according to " treatinging deficiency with tonification ", is constituted with based on tonic, not enough with help energy and blood of human body negative and positive, with
Treat the prescription of various asthenic symptoms, referred to as tonic recipe.
Indication：This class side medicine is primarily adapted for use in two aspects：One has been use up for disease and evil, because of the disease that prolonged illness has a delicate constitution
Card, to build up health, promotes body recovery health；Two is that, for pathogen being excessive but vital QI weak, healthy tendency can not resist the disease of perverse trend, often with dispel
Evil medicine is same to be used, to reach the purpose of strengthening vital QI to eliminate pathogenic factors.
Hepatic and renal function is not enough, refers mainly to the deficiency of liver-yin and kidney-yin.That is essence and blood is empty few.Dizziness so occurs,（Because brain hides marrow,
By kidney essense, and blood is the material base of mind activity, thus liver kidney deficiency can brain lose support and it is dizzy）.Xerophtalmia（Because of liver blood and
Kidney essense has eye-candy function, and it refers to just have moistening for liver blood and kidney essense foster to fear visual acuity is obtained from the sufficient blood supply of the eyes, can just see all of world）.
It is likely to both hands chatter phenomenon occur,（Because liver blood and kidney essense are nutritious to joint and make moist effect）.Being also possible to can apoplexy（Cause
The deficiency of liver-yin and kidney-yin, then powerless system is positive, and now described cerebrovas-cularaccident phenomenon then easily occurs in the overabundance of yang）Etc..
Traditional Chinese medical theory thinks that kidney is " the congenital foundation ", " Source of life ".Its physiological function is store essential substances, main water, leads and receive
Gas, main bone, raw marrow, bone blood, skin or even tooth, ear with people have greatest relation.And " kidney deficiency " is divided into " kidney yin
It is empty " and " kidney-yang deficiency ".
1st, kidney-yin deficiency
" kidney yin " is also known as " Kidney-Yin ", " Kidney-Yin ", " kidney water ", refers to the moon essence of kidney.Kidney yin plays the role of to nourish internal organs, is cloudy human body
Liquid it is basic.《Jing Yue's complete work》Claim：" the moon gas of the five internal organs, non-this can not be grown." kidney-yin deficiency symptom is：Dysphoria in chestpalms-soles, mouth parched and tongue scorched,
Bad, the red tongue body of sleep, less fur, thready rapid pulse；
2nd, kidney-yang deficiency
Kidney yang is also known as " kidney-Yang ", " Yuanyang ", " fire from the gater of life ".Refer to the yang-energy of kidney.It is dirty that kidney yang plays the role of the foster internal organs of temperature, is human body
Yang-energy it is basic.Kidney yang and kidney yin interdependence, both combine, to maintain the physiological function and vital movement of human body.Kidney-yang deficiency
Symptom is：Limb is cold, cold, pale complexion, and impotence, premature ejaculation, spirit, tongue nature is light, thin lingual fur, and arteries and veins is slow etc..
Read here, we can be found that：The sexual function health problems such as " impotence ", " premature ejaculation " and kidney-yang deficiency have certain pass
System.Kidney-yang deficiency of the various kidney tonifying products so-called " establishing-Yang " aiming at theory of traditional Chinese medical science.And in fact, in Traditional Chinese medical theory
" tonifying kidney and strengthening yang " is the theory of traditional Chinese medical science of human body resist the disease, and men and women all can be with tonifying kidney and strengthening yang, rather than the literal benefit male of narrow sense
" sun tool ".
The content of the invention
It is an object of the invention to provide a kind of Chinese medicine preparation safely, effectively, having no side effect.
It is a further object to provide a kind of Chinese patent drug for tonifying the liver and kidney and its preparation technology.
To achieve these goals, the present invention summarizes clinical experience composition effective formula and drug for many years according to theory of traditional Chinese medical science.
Its prescription is as follows：
60~100 parts of cultivated land, 60~100 parts of raw ephedra, 60~100 parts of semen brassicae, 60~100 parts of baked ginger, the bark of eucommia 60~100
Part, 60~100 parts of rhizoma cibotii, 60~100 parts of Chinese cassia tree, 60~100 parts of Semen Cuscutae, 60~100 parts of the root of bidentate achyranthes, 60~100 parts of dipsacus root, silk
60~100 parts of melon network, adds proper auxiliary materials to be made 1000 parts after extraction.
The beneficial effects of the invention are as follows：
1st, prescription of the invention is compared with the prescription for the treatment of similar disease at present, and reasonable recipe, flavour of a drug are fewer but better, and each medicine is produced
Synergy, can produce good treatment to tonify the liver and kidney effect.
2nd, preparation process research and design of the invention is careful rationally, pharmacodynamics is combined with active component and has formulated extraction
Technique, tonifies the liver and kidney in good, and treatment farthest removes impurity on the basis of tonifying the liver and kidney, it is ensured that the drug effect of prescription,
Injection volume is reduced again, is that the Study on Forming of preparation is laid a good foundation.
3rd, the present invention can also make dosage form series, including capsule, tablet, particle for the treatment Chinese patent drug that tonifies the liver and kidney
Agent, soft capsule or other formulations etc..These formulations all have that easy to use, good stability, quality controllability be good, patient adapts to
The advantages of property is good.
Specific embodiment
With reference to embodiment, the present invention is further illustrated, but is not limited thereto.
Embodiment 1
One kind is made up for the Chinese patent drug that tonifies the liver and kidney of the Chinese medicine of following mass parts：80 parts of cultivated land, 100 parts of raw ephedra, sinapsis alba
100 parts of son, 100 parts of baked ginger, 100 parts of the bark of eucommia, 60 parts of rhizoma cibotii, 100 parts of Chinese cassia tree, 60 parts of Semen Cuscutae, 100 parts of the root of bidentate achyranthes, 60 parts of dipsacus root,
100 parts of luffa.
Embodiment 2
One kind is made up for the Chinese patent drug that tonifies the liver and kidney of the Chinese medicine of following mass parts：80 parts of cultivated land, 80 parts of raw ephedra, sinapsis alba
100 parts of son, 70 parts of baked ginger, 100 parts of the bark of eucommia, 60 parts of rhizoma cibotii, 80 parts of Chinese cassia tree, 60 parts of Semen Cuscutae, 100 parts of the root of bidentate achyranthes, 60 parts of dipsacus root, silk
80 parts of melon network.
Embodiment 3
One kind is made up for the Chinese patent drug that tonifies the liver and kidney of the Chinese medicine of following mass parts：100 parts of cultivated land, 100 parts of raw ephedra, in vain
70 parts of mustard seed, 70 parts of baked ginger, 100 parts of the bark of eucommia, 60 parts of rhizoma cibotii, 70 parts of Chinese cassia tree, 60 parts of Semen Cuscutae, 100 parts of the root of bidentate achyranthes, 60 parts of dipsacus root,
100 parts of luffa.
Embodiment 4
One kind is made up for the Chinese patent drug that tonifies the liver and kidney of the Chinese medicine of following mass parts：80 parts of cultivated land, 100 parts of raw ephedra, sinapsis alba
90 parts of son, 90 parts of baked ginger, 100 parts of the bark of eucommia, 90 parts of rhizoma cibotii, 100 parts of Chinese cassia tree, 90 parts of Semen Cuscutae, 90 parts of the root of bidentate achyranthes, 60 parts of dipsacus root, silk
90 parts of melon network.
A kind of preparation for the capsule that tonifies the liver and kidney of embodiment 5
The Chinese patent drug of embodiment 1~4 can be made one kind and tonified the liver and kidney capsule by following technique, comprise the following steps that：
（1）Each medicine is weighed in proportion；
（2）All medicinal materials are added water to cook 2 times, decocting liquid, filtration, are stood, and take supernatant concentration to appropriate；
（3）Lactose, appropriate microcrystalline cellulose are added, are mixed, be made particle, dried, whole grain,
It is standby；
（4）Particle adds 1% magnesium stearate, 1% silica to mix, and filling capsule is made the Chinese patent drug for tonifying the liver and kidney；
Application method：Orally.
A kind of preparation of the piece that tonifies the liver and kidney of embodiment 6
The Chinese patent drug of embodiment 1~4 can be made one kind and tonified the liver and kidney piece by following technique, comprise the following steps that：
（1）Each medicine is weighed in proportion；
（2）All medicinal materials are added water to cook 2 times, decocting liquid, filtration, are stood, and take supernatant concentration to appropriate；
（3）Lactose, appropriate microcrystalline cellulose are added, are mixed, be made particle, dried, whole grain,
It is standby；
（4）Particle adds 1% magnesium stearate, 1% silica to mix, and compressing tablet is made the Chinese patent drug for tonifying the liver and kidney；
Application method：Orally.
A kind of scattered preparation of tonifying the liver and kidney of embodiment 7
The Chinese patent drug of embodiment 1~4 can be made one kind and tonify the liver and kidney scattered by following technique, comprise the following steps that：
（1）Each medicine is weighed in proportion；
（2）All medicinal materials are added water to cook 2 times, decocting liquid, filtration, are stood, and take supernatant concentration to appropriate；
（3）Lactose, appropriate microcrystalline cellulose are added, are mixed, be made particle, dry, pulverize,
It is standby；
（4）Fine powder adds 1% silica to mix, and pack is made the Chinese patent drug for tonifying the liver and kidney；
Application method：Warm water is taken after mixing it with water.
A kind of preparation of the particle that tonifies the liver and kidney of embodiment 8
The Chinese patent drug of embodiment 1~4 can be made one kind and tonified the liver and kidney particle by following technique, comprise the following steps that：
（1）Each medicine is weighed in proportion；
（2）All medicinal materials are added water to cook 2 times, decocting liquid, filtration, are stood, and take supernatant concentration to appropriate；
（3）Lactose, appropriate microcrystalline cellulose are added, are mixed, be made particle, dried, whole grain,
It is standby；
（4）Particle adds 1% magnesium stearate, 1% silica to mix, and pack is made the Chinese patent drug for tonifying the liver and kidney；
Application method：Warm water is taken after mixing it with water.
A kind of preparation of the soft capsule that tonifies the liver and kidney of embodiment 9
The Chinese patent drug of embodiment 1~4 can be made one kind and tonified the liver and kidney soft capsule by following technique, comprise the following steps that：
（1）Each medicine is weighed in proportion；
（2）All medicinal materials are added water to cook 2 times, decocting liquid, filtration, are stood, and take supernatant concentration to appropriate；
（3）Dry, be made standby after fine powder；
（4）Appropriate soybean oil is added, is mixed, as content, prepare suitable rubber, soft capsule is made on encapsulating machine,
It is made the Chinese patent drug for tonifying the liver and kidney；
Application method：Warm water is taken after mixing it with water.
Claims (8)
1. a kind of Chinese patent drug for tonifying the liver and kidney, it is characterised in that be mainly made up of the Chinese medicine of following mass parts：Cultivated land 60
~100 parts, 60~100 parts of raw ephedra, 60~100 parts of semen brassicae, 60~100 parts of baked ginger, 60~100 parts of the bark of eucommia, rhizoma cibotii 60~
100 parts, 60~100 parts of Chinese cassia tree, 60~100 parts of Semen Cuscutae, 60~100 parts of the root of bidentate achyranthes, 60~100 parts of dipsacus root, luffa 60~100
Part, add proper auxiliary materials to be made 1000 parts after extraction.
2. the Chinese patent drug for tonifying the liver and kidney according to claim 1, it is characterised in that the main Chinese medicine system by following mass parts
Into：60~90 parts of cultivated land, 60~100 parts of raw ephedra, 60~100 parts of semen brassicae, 60~100 parts of baked ginger, 60~100 parts of the bark of eucommia,
60~90 parts of rhizoma cibotii, 60~100 parts of Chinese cassia tree, 60~90 parts of Semen Cuscutae, 60~100 parts of the root of bidentate achyranthes, 60~90 parts of dipsacus root, luffa 60
~100 parts.
3. the Chinese patent drug for tonifying the liver and kidney according to claim 2, it is characterised in that the main Chinese medicine by following mass parts
It is made：80 parts of cultivated land, 100 parts of raw ephedra, 100 parts of semen brassicae, 100 parts of baked ginger, 100 parts of the bark of eucommia, 60 parts of rhizoma cibotii, 100 parts of Chinese cassia tree,
60 parts of Semen Cuscutae, 100 parts of the root of bidentate achyranthes, 60 parts of dipsacus root, 100 parts of luffa.
4. the Chinese patent drug according to any one of claims 1 to 3, it is characterised in that can also be added pharmaceutically in the Chinese patent drug
The auxiliary material of permission is made oral formulations.
5. the preparation method of the Chinese patent drug for tonifying the liver and kidney described in any one of Claims 1 to 4, comprises the following steps：
（1）Each medicine is weighed in proportion；
（2）All medicinal materials are added water to cook 2 times, decocting liquid, filtration, are stood, and take supernatant concentration to appropriate；
（3）Lactose, appropriate microcrystalline cellulose are added, is mixed, be made particle, dried, whole grain；
（4）By gained particle, appropriate silica, magnesium stearate are added, be made the Chinese patent drug for tonifying the liver and kidney.
6. preparation method according to claim 5, step（2）Characterized in that, the decocting for using boil the condition of technology for：
Plus 8~10 times of water, soak 0.5~1h.
7. preparation method according to claim 5, it is characterised in that step（2）The technical conditions of the decocting cooking method are：
Decoct for the first time 3 hours, second decocts 2 hours, filtration, merging filtrate stands, take supernatant concentration to appropriate.
8. preparation method according to claim 5, it is characterised in that step（4）Concrete operations be：According to different doses
Type, using different auxiliary material, is mixed evenly to prepare suitable particulate, is made the Chinese patent drug for tonifying the liver and kidney.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710162623.2A CN106798909A (en) | 2017-03-18 | 2017-03-18 | A kind of Chinese patent drug and its preparation technology for tonifying the liver and kidney |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710162623.2A CN106798909A (en) | 2017-03-18 | 2017-03-18 | A kind of Chinese patent drug and its preparation technology for tonifying the liver and kidney |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106798909A true CN106798909A (en) | 2017-06-06 |
Family
ID=58987118
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710162623.2A Pending CN106798909A (en) | 2017-03-18 | 2017-03-18 | A kind of Chinese patent drug and its preparation technology for tonifying the liver and kidney |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106798909A (en) |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106176931A (en) * | 2016-08-31 | 2016-12-07 | 佛山市弘泰药物研发有限公司 | A kind of for blood circulation promoting and blood stasis dispelling, anginal Chinese patent medicine and preparation technology thereof |
-
2017
- 2017-03-18 CN CN201710162623.2A patent/CN106798909A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106176931A (en) * | 2016-08-31 | 2016-12-07 | 佛山市弘泰药物研发有限公司 | A kind of for blood circulation promoting and blood stasis dispelling, anginal Chinese patent medicine and preparation technology thereof |
Non-Patent Citations (1)
| Title |
|---|
| 孙世发: "《中华医方 外科篇 下及骨伤科篇》", 28 February 2015, 科学技术文献出版社 * |
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Application publication date: 20170606 |