CN109303906A - It is a kind of for warming and activating meridian, the long-acting moxibustion plaster of damp dispelling and pain relieving and preparation method thereof - Google Patents
It is a kind of for warming and activating meridian, the long-acting moxibustion plaster of damp dispelling and pain relieving and preparation method thereof Download PDFInfo
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- CN109303906A CN109303906A CN201811258309.5A CN201811258309A CN109303906A CN 109303906 A CN109303906 A CN 109303906A CN 201811258309 A CN201811258309 A CN 201811258309A CN 109303906 A CN109303906 A CN 109303906A
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- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/282—Artemisia, e.g. wormwood or sagebrush
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
- A61H39/00—Devices for locating or stimulating specific reflex points of the body for physical therapy, e.g. acupuncture
- A61H39/06—Devices for heating or cooling such points within cell-life limits
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Abstract
The invention belongs to external drug fields more particularly to a kind of for warming and activating meridian, the long-acting moxibustion plaster of damp dispelling and pain relieving and preparation method thereof.The long-acting moxibustion plaster of the present invention is made of Chen Ai, rhizoma zingiberis, fern fiber crops, chestnut shell, raw green salt, the shallot root base of a fruit and wormwood essential oil.Moxibustion plaster of the present invention imports principle using moxa-moxibustion fuel factor and essential oil, accelerates Traditional Chinese medicine permeation, realizes moxibustion, medication, the triple therapeutic effects of physical therapy.Through testing, moxibustion plaster of the present invention has the effect of warming and activating meridian, damp dispelling and pain relieving, expelling wind and clearing away cold, can alleviate joint or muscle rigidity caused by the disease such as cervical spondylosis, protrusion of lumber intervertebral disc, scapulohumeral periarthritis, lumbar muscle strain, rheumatic arthritis rapidly, ache, the malaise symptoms such as swelling.Moxibustion plaster of the present invention uses spontaneous hot mode, i.e. patch is use, easy to operate, safety and environmental protection, without professional's operation, and the present invention is long life product, and the single moxibustion time was up to 6-8 hours, by carrying out prolonged moxibustion infiltration to affected part, moxibustion effect is more significant.
Description
Technical field
The invention belongs to external drug fields more particularly to a kind of for warming and activating meridian, the long-acting moxibustion plaster of damp dispelling and pain relieving
And preparation method thereof.
Background technique
Moxa-moxibustion belongs to the moxibustion therapy in Chinese medicine acupuncture therapy, is the moxa made of folium artemisiae argyi based on Chinese medicine meridian theory
The Ai heat stimulation body surface point or privileged site of generation, Human Physiology biochemical function is adjusted by the activity of stimulating Qi of meridian, from
And so as to achieve the aim of preventing and treating diseases.Moxibustion has clearing and activating the channels and collaterals, promoting qi circulation and relieving pain, dries by cold, scattered stasis detumescence, help gas
Blood, solid first production of sperm, warm palace help pregnant, toxin-expelling and face nourishing, prolong life and other effects, are usually used in treating that postpartum channels and collaterals are unsmooth and trick ice
The diseases such as cool, dysmenorrhea, irregular menstruation, stomachache.
Traditional puncture is curative for effect, but its is inconvenient, need to be with the smoked moxibustion of fire, easy burn patients, not only not in therapeutic process
Safety, and it is unfavorable for environmental protection;Modern moxa-moxibustion mainly by the moxa-moxibustions such as hot moxibustion instrument instrument come moxibustion treatment, have it is smokeless,
Without fire, free of contamination feature, however its therapy is single, and curative effect is unstable, and curative effect is slight sometimes, and therapeutic response is then excessively sometimes
Strongly, patient is difficult to bear.
In addition, moxa-moxibustion also has more stringent limitation to its target user, moreover, many patients can also after applying moxa-moxibustion
Occur dizziness, dim eyesight, nausea, insomnia, fatigue and weak, drowsiness, excessive internal heat, mouth parched and tongue scorched, erythema, flush, post-moxibustion sore, fever,
The adverse reactions such as pale complexion, palpitation, general malaise, wherein especially most commonly seen with insomnia, excessive internal heat, erythema, flush.
The drawbacks described above of moxa-moxibustion greatly limits its application.Therefore, be badly in need of in clinic it is a kind of it is easy to operate, make
With safety, the new moxibustion method that curative for effect, adverse reaction is few.
Summary of the invention
In order to overcome moxa-moxibustion is inconvenient, security risk is big, not environmentally, the moxibustion time is short, uncertain therapeutic efficacy is cut, adverse reaction
The defects of more, the present invention provides it is a kind of it is easy to operate, using safe, widely applicable, curative for effect, adverse reaction is few, cost
Cheap long-acting moxibustion plaster.
The present invention is to be made of pack and heating pack for warming and activating meridian, the long-acting moxibustion plaster of damp dispelling and pain relieving, the pack
It pastes in the heating pack, Chinese medicine package is made of the raw material of following weight parts:
Chen Ai 85-92, rhizoma zingiberis 2.5-3.0, fern fiber crops 3.5-5.0,
Chestnut shell 2.0-2.5, raw green salt 1.2-1.6, shallot root base of a fruit 1.2-1.6,
Wormwood essential oil 0.1-0.8;
Heating pack is made of fever miberal powder.
Further, the pack for including in the long-acting moxibustion plaster of the present invention is made through following step:
(1) by Chen Ai, rhizoma zingiberis, raw green salt and the shallot root base of a fruit are dry, mix, smash it through 80 meshes, obtain mixed powder;
(2) fern fiber crops clean dry is placed on frying 30 minutes in 120-125 DEG C of frying pan, is crushed after cooling, cross 80 mesh
Sieve obtains fern fiber crops powder;
(3) chestnut shell clean dry is placed in 200-220 DEG C of frying pan and is continuously fried to carbonization, powder after cooling
It is broken, it crosses 80 meshes and obtains chestnut shell powder;
(4) above-mentioned mixed powder, fern fiber crops powder and chestnut shell powder are mixed, slowly wormwood essential oil is added after mixing evenly
Wherein, it grinds when being added, until becoming flowing water shape fine grained powder mixture, gained flowing water shape fine grained powder mixture is packed into
In non-woven bag to get arrive the pack.
Preferably, the parts by weight that each raw material of the pack is made are:
Chen Ai 90, rhizoma zingiberis 2.8, fern fiber crops 4.5,
Chestnut shell 2.4, raw green salt 1.5, the shallot root base of a fruit 1.5,
Wormwood essential oil 0.5.
In order to be more effectively alleviated the positions such as waist, neck, shoulder, back, knee ache with it is stiff, the long-acting moxibustion plaster of the present invention may be used also
Following weight parts are added in pack composition of raw materials:
For the heavier patient of symptom, in order to strengthen curative effect, the long-acting moxibustion plaster of the present invention can also match in above-mentioned pack raw material
Following weight parts are added on the basis of side:
Myrrh 0.8-1.2, root of Dahurain angelica 0.5-0.6, caulis akebiae 0.3-0.4,
Bat's faces 0.3-0.4, raw excrementum pteropi 0.5-0.6.
In order to meet the treatment needs of menstruating women and woman preparing for pregnancy, enhance warm palace effect, the long-acting moxibustion plaster of the present invention
Also following weight parts can be added in pack composition of raw materials:
In addition, being that following weight is added into pack composition of raw materials the present invention also provides the long-acting moxibustion plaster of sufficient patch type
Part:
Bamboo vinegar 2.0-2.5, bamboo charcoal 1.2-1.6, conchiolin powder 1.0-1.2,
Ascorbic acid 0.2-0.3, campanulaceae root extract 0.5-0.8.
It is that following weight is added into pack composition of raw materials meanwhile the present invention also provides the long-acting moxibustion plaster of eye sticker type
Part: camomile extract 2.5-3.0.
In addition to this, the application the invention further relates to above-mentioned long-acting moxibustion plaster in preparation external application damp dispelling and pain relieving drug.
The invention further relates to above-mentioned long-acting moxibustion plasters to treat palace cold, dysmenorrhea, neurasthenia, insomnia, headache, stomach in preparation
Bitterly, the application in constipation, diarrhea, abdominal pain, flu, infantile convulsion, hypertension, diabetes, eye strain or weight-reducing external drug.
To sum up, moxibustion plaster of the present invention imports principle using moxa-moxibustion fuel factor and essential oil, accelerates Traditional Chinese medicine permeation, realize moxibustion,
Medication, the triple therapeutic effects of physical therapy.The present invention is debugged by screening and repeating extensively, is changed to moxibustion plaster pack formula
Into joined through the fiber crops of fern made from special process and Chinese chestnut on the basis of the ingredients such as Chen Ai, rhizoma zingiberis, raw green salt, the shallot root base of a fruit
Shell component, it has been found that the treatment that can be significantly improved moxibustion plaster damp dispelling and pain relieving after fern fiber crops component, alleviate the swelling and pain of neck shoulder stiffness is added
Effect, chestnut shell component, which is added, can then reduce the incidence of the adverse reactions such as its excessive internal heat, erythema, flush.
Through testing, moxibustion plaster of the present invention has the effect of warming and activating meridian, damp dispelling and pain relieving, expelling wind and clearing away cold, can alleviate rapidly
Joint or muscle rigidity, acid caused by the disease such as cervical spondylosis, protrusion of lumber intervertebral disc, scapulohumeral periarthritis, lumbar muscle strain, rheumatic arthritis
Bitterly, the malaise symptoms such as swelling, this product, which is used for a long time, can also adjust qi and blood, helps sun to consolidate, improves body microcirculation, promoting human body
Self-repairing capability increases immunity of organisms, health care.In addition, being observed for a long time, moxibustion plaster of the present invention can also be used to assist
Treat palace cold, dysmenorrhea, neurasthenia, insomnia, headache, stomachache, constipation, diarrhea, abdominal pain, flu, infantile convulsion, hypertension, sugar
Disease, a variety of diseases such as eye strain are urinated, is adhered to using additionally aiding weight-reducing and body beautification.
Moxibustion plaster of the present invention uses spontaneous hot mode, i.e. patch is use, easy to operate, safety and environmental protection, without professional behaviour
Make.In addition, moxibustion plaster of the present invention is long life product, the single moxibustion time is prolonged by carrying out to affected part up to 6-8 hours
Moxibustion infiltration, moxibustion effect is more significant, and moxibustion plaster adverse reaction of the present invention is less, and preparation cost is cheap, therefore very suitable
Close current physical therapy and the health care market demand.
Specific embodiment
Illustrate embodiments of the present invention below by way of specific specific example, those skilled in the art can be by this specification
Other advantages and efficacy of the present invention can be easily understood for disclosed content.The present invention can also pass through in addition different specific realities
The mode of applying is embodied or practiced, the various details in this specification can also based on different viewpoints and application, without departing from
Various modifications or alterations are carried out under spirit of the invention.
Unless otherwise defined, all technical and scientific terms and those skilled in the art of the present technique used in the present invention are usual
The meaning of understanding is identical.Those skilled in the art can also use with method described in the embodiment of the present invention, equipment,
Any method, equipment and the material of the similar or equivalent prior art of material realizes the present invention.Below in conjunction with specific embodiment
It is described in detail with using effect of the comparative example to the long-acting moxibustion plaster of the present invention.
Embodiment 1
A kind of to be made of for warming and activating meridian, the long-acting moxibustion plaster of damp dispelling and pain relieving pack and heating pack, pack, which is pasted, to be sent out
Heat is wrapped, and Chinese medicine package is made of the raw material of following weight parts:
Chen Ai 90, rhizoma zingiberis 2.8, fern fiber crops 4.5,
Chestnut shell 2.4, raw green salt 1.5, the shallot root base of a fruit 1.5,
Wormwood essential oil 0.5.
Heating pack is made of fever miberal powder.
Pack the preparation method is as follows:
(1) by Chen Ai, rhizoma zingiberis, raw green salt and the shallot root base of a fruit are dry, mix, smash it through 80 meshes, obtain mixed powder;
(2) fern fiber crops clean dry is placed on frying 30 minutes in 120-125 DEG C of frying pan, is crushed after cooling, cross 80 mesh
Sieve obtains fern fiber crops powder;
(3) chestnut shell clean dry is placed in 200-220 DEG C of frying pan and is continuously fried to carbonization, powder after cooling
It is broken, it crosses 80 meshes and obtains chestnut shell powder;
(4) above-mentioned mixed powder, fern fiber crops powder and chestnut shell powder are mixed, slowly wormwood essential oil is added after mixing evenly
Wherein, it grinds when being added, until becoming flowing water shape fine grained powder mixture, gained flowing water shape fine grained powder mixture is packed into
In non-woven bag to get arrive pack.
Embodiment 2
It is a kind of for warming and activating meridian, the long-acting moxibustion plaster of damp dispelling and pain relieving, be exclusively used in alleviating the positions such as waist, neck, shoulder, back, knee
Ache with it is stiff, be made of pack and heating pack, pack is pasted in heating pack, Chinese medicine package by following weight parts raw material
It is made:
Heating pack is made of fever miberal powder.
Pack the preparation method is as follows:
(1) by Chen Ai, rhizoma zingiberis, lopseed, lycopodium calvatum, Radix Notoginseng, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Rhizoma Et Radix Notopterygii, ramulus cinnamomi, Chinese ephedra, olibanum, raw blueness
Salt and the shallot root base of a fruit are dry, mix, smash it through 80 meshes, obtain mixed powder;
(2) fern fiber crops clean dry is placed on frying 30 minutes in 120-125 DEG C of frying pan, is crushed after cooling, cross 80 mesh
Sieve obtains fern fiber crops powder;
(3) chestnut shell clean dry is placed in 200-220 DEG C of frying pan and is continuously fried to carbonization, powder after cooling
It is broken, it crosses 80 meshes and obtains chestnut shell powder;
(4) above-mentioned mixed powder, fern fiber crops powder and chestnut shell powder are mixed, slowly wormwood essential oil is added after mixing evenly
Wherein, it grinds when being added, until becoming flowing water shape fine grained powder mixture, gained flowing water shape fine grained powder mixture is packed into
In non-woven bag to get arrive pack.
Embodiment 3
It is a kind of for warming and activating meridian, the long-acting moxibustion plaster of damp dispelling and pain relieving, be exclusively used in alleviating the more serious waist of symptom, neck,
The positions such as shoulder, back, knee ache with it is stiff, be made of pack and heating pack, pack is pasted in heating pack, and Chinese medicine package is under
The raw material for stating parts by weight is made:
Heating pack is made of fever miberal powder.
Pack the preparation method is as follows:
(1) by Chen Ai, rhizoma zingiberis, lopseed, lycopodium calvatum, Radix Notoginseng, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Rhizoma Et Radix Notopterygii, ramulus cinnamomi, Chinese ephedra, olibanum, myrrh,
The root of Dahurain angelica, caulis akebiae, bat's faces, raw excrementum pteropi, raw green salt and the shallot root base of a fruit are dry, mix, smash it through 80 meshes, obtain mixing medicine
Powder;
(2) fern fiber crops clean dry is placed on frying 30 minutes in 120-125 DEG C of frying pan, is crushed after cooling, cross 80 mesh
Sieve obtains fern fiber crops powder;
(3) chestnut shell clean dry is placed in 200-220 DEG C of frying pan and is continuously fried to carbonization, powder after cooling
It is broken, it crosses 80 meshes and obtains chestnut shell powder;
(4) above-mentioned mixed powder, fern fiber crops powder and chestnut shell powder are mixed, slowly wormwood essential oil is added after mixing evenly
Wherein, it grinds when being added, until becoming flowing water shape fine grained powder mixture, gained flowing water shape fine grained powder mixture is packed into
In non-woven bag to get arrive pack.
Embodiment 4
It is a kind of for warming and activating meridian, the long-acting moxibustion plaster of damp dispelling and pain relieving, be exclusively used in controlling for menstruating women and woman preparing for pregnancy
It treats and needs, enhance warm palace effect, be made of pack and heating pack, pack is pasted in heating pack, and Chinese medicine package is by following heavy
The raw material of amount part is made:
Heating pack is made of fever miberal powder.
Pack the preparation method is as follows:
(1) by Chen Ai, rhizoma zingiberis, motherwort, cortex moutan, radix achyranthis bidentatae, Radix Angelicae Sinensis, Rhizoma Chuanxiong, curcuma zedoary, ramulus cinnamomi, radix rehmanniae preparata, Radix Paeoniae Alba, Radix Astragali,
Safflower, raw green salt and the shallot root base of a fruit are dry, mix, smash it through 80 meshes, obtain mixed powder;
(2) fern fiber crops clean dry is placed on frying 30 minutes in 120-125 DEG C of frying pan, is crushed after cooling, cross 80 mesh
Sieve obtains fern fiber crops powder;
(3) chestnut shell clean dry is placed in 200-220 DEG C of frying pan and is continuously fried to carbonization, powder after cooling
It is broken, it crosses 80 meshes and obtains chestnut shell powder;
(4) above-mentioned mixed powder, fern fiber crops powder and chestnut shell powder are mixed, slowly wormwood essential oil is added after mixing evenly
Wherein, it grinds when being added, until becoming flowing water shape fine grained powder mixture, gained flowing water shape fine grained powder mixture is packed into
In non-woven bag to get arrive pack.
Embodiment 5
A kind of to be made of for warming and activating meridian, the sufficient long-acting moxibustion plaster of patch type of damp dispelling and pain relieving pack and heating pack, pack is glutinous
It is attached in heating pack, Chinese medicine package is made of the raw material of following weight parts:
Heating pack is made of fever miberal powder.
Pack the preparation method is as follows:
(1) by Chen Ai, rhizoma zingiberis, bamboo charcoal, conchiolin powder, raw green salt and the shallot root base of a fruit are dry, mix, smash it through 80
Mesh obtains mixed powder;
(2) fern fiber crops clean dry is placed on frying 30 minutes in 120-125 DEG C of frying pan, is crushed after cooling, cross 80 mesh
Sieve obtains fern fiber crops powder;
(3) chestnut shell clean dry is placed in 200-220 DEG C of frying pan and is continuously fried to carbonization, powder after cooling
It is broken, it crosses 80 meshes and obtains chestnut shell powder;
(4) above-mentioned mixed powder, fern fiber crops powder, chestnut shell powder, ascorbic acid and campanulaceae root water extract are mixed, stirring is equal
Slowly bamboo vinegar and wormwood essential oil are added thereto after even, ground when being added, until become flowing water shape fine grained powder mixture,
Gained flowing water shape fine grained powder mixture is fitted into non-woven bag to get pack is arrived.
Embodiment 6
A kind of to be made of for warming and activating meridian, the long-acting moxibustion plaster of eye sticker type of damp dispelling and pain relieving pack and heating pack, pack is glutinous
It is attached in heating pack, Chinese medicine package is made of the raw material of following weight parts:
Heating pack is made of fever miberal powder.
Pack the preparation method is as follows:
(1) by Chen Ai, rhizoma zingiberis, raw green salt and the shallot root base of a fruit are dry, mix, smash it through 80 meshes, obtain mixed powder;
(2) fern fiber crops clean dry is placed on frying 30 minutes in 120-125 DEG C of frying pan, is crushed after cooling, cross 80 mesh
Sieve obtains fern fiber crops powder;
(3) chestnut shell clean dry is placed in 200-220 DEG C of frying pan and is continuously fried to carbonization, powder after cooling
It is broken, it crosses 80 meshes and obtains chestnut shell powder;
(4) chamomile is removed into impurity, 10 times of 30% ethanol waters measured is added after rinsing, dry, crushing, impregnate 45
Refluxing extraction 30 minutes after minute, filtering, filtrate is spare, repeats to extract 1 time by filter residue under the same conditions, and filtering merges two
Secondary filtrate obtains camomile extract after vacuum drying;
(5) above-mentioned mixed powder, fern fiber crops powder, chestnut shell powder and camomile extract are mixed, after mixing evenly slowly
Wormwood essential oil is added thereto, is ground when being added, until becoming flowing water shape fine grained powder mixture, by gained flowing water shape particulate
Powder mix is fitted into non-woven bag to arrive pack.
Comparative example 1
A kind of to be made of for warming and activating meridian, the long-acting moxibustion plaster of damp dispelling and pain relieving pack and heating pack, pack, which is pasted, to be sent out
Heat is wrapped, and Chinese medicine package is made of the raw material of following weight parts:
Chen Ai 90, rhizoma zingiberis 2.8,
Raw green salt 1.5, the shallot root base of a fruit 1.5,
Wormwood essential oil 0.5.
Heating pack is made of fever miberal powder.
Pack the preparation method is as follows:
(1) by Chen Ai, rhizoma zingiberis, raw green salt and the shallot root base of a fruit are dry, mix, smash it through 80 meshes, obtain mixed powder;
(2) wormwood essential oil is slowly added into above-mentioned mixed powder, is ground when being added, until it is thin to become flowing water shape
Gained flowing water shape fine grained powder mixture is fitted into non-woven bag to get pack is arrived by grain powder mix.
Comparative example 2
A kind of to be made of for warming and activating meridian, the long-acting moxibustion plaster of damp dispelling and pain relieving pack and heating pack, pack, which is pasted, to be sent out
Heat is wrapped, and Chinese medicine package is made of the raw material of following weight parts:
Chen Ai 90, rhizoma zingiberis 2.8,
Chestnut shell 2.4, raw green salt 1.5,
The shallot root base of a fruit 1.5, wormwood essential oil 0.5.
Heating pack is made of fever miberal powder.
Pack the preparation method is as follows:
(1) by Chen Ai, rhizoma zingiberis, raw green salt and the shallot root base of a fruit are dry, mix, smash it through 80 meshes, obtain mixed powder;
(2) chestnut shell clean dry is placed in 200-220 DEG C of frying pan and is continuously fried to carbonization, powder after cooling
It is broken, it crosses 80 meshes and obtains chestnut shell powder;
(3) above-mentioned mixed powder and chestnut shell powder are mixed, is after mixing evenly slowly added thereto wormwood essential oil, side
Side grinding is added, until becoming flowing water shape fine grained powder mixture, gained flowing water shape fine grained powder mixture is packed into non-woven fabrics
Bag in get arrive pack.
Pharmacodynamics test
Pharmacodynamics test is carried out to long-acting moxibustion plaster obtained in above-described embodiment 1 and comparative example 1-2.
One, test material
Test medicine: long-acting moxibustion plaster made from embodiment 1 and comparative example 1-2.
Positive drug: Votalin Ointment.
Experimental animal: Wistar rat, male, weight 180-200g.
Inducer: brewer's yeast.
Two, modeling method
After rat adapts to 3d in feeding environment, fasting for 24 hours, after on-test, it is each first to survey the measurement of pain method using heat radiation
The Basic Pain Threshold value of toes after group rat is left and right, then every right hind foot of rat toe subcutaneous injection into model group and test group
20% brewer's yeast aqueous solution 0.1ml, to induce inflammation.After 2.5h, test group gives test medicine or positive drug, model
Group gives physiological saline.It is same that the pain threshold that pain method measures the left and right rear toes of each group rat respectively is surveyed using heat radiation after 1h.
Three, test method
Test grouping: tested rat is randomly divided into 6 groups, every group 10, respectively blank group, model group, positive drug group, reality
Apply 1 group of example, 1 group of comparative example and 2 groups of comparative example.
Medication: toe position binding moxibustion plaster or smearing drug after right.
Four, test result
Observation index: the pain threshold of the left and right rear toes in each group rat administration front and back is recorded respectively.
Toes pain threshold after each rats in test groups of table 1 administration front and back is left and right
Note: it compares administration front and back:**P≤0.05;***P≤0.01.
Test result: from table 1 it follows that compared with model group, the toes threshold of pain behind the right side of each test medicine group rat
Value has different degrees of raising, and each group test medicine is prompted to all have certain analgesic effect.Compared to comparative example 1 and 2 group,
Example 1 group analgesic effect is more significant, close to positive drug Votalin Ointment.In comparison, 1 group of comparative example and comparative example
2 groups numb due to having lacked fern in composition of raw materials, and therapeutic effect is far away from example 1 group, to illustrate example 1 group moxibustion plaster
Composition of raw materials and preparation process be better than comparative example group.
Clinical test
Moxibustion plaster (embodiment 1) of the present invention and control group moxibustion plaster (comparative example 1-2) are verified in observation and positive drug (is helped
His woods ointment) to the therapeutic effect and adverse reaction of knee stiffness and pain.
One, case selection and grouping
Gonalgia patient 240 caused by arthritis are randomly divided into 4 groups, every group each 60.The each group age, gender,
The course of disease, the cause of disease, gonalgia degree no difference of science of statistics (p > 0.05).
Two, it is included in standard
(1) age 40-60 one full year of life;
(2) it tests in first 1 week and did not carried out other analgesia therapies;
(3) without other serious organ diseases.
Three, treatment method
Test group and control group use corresponding moxibustion plaster, each 1 daily morning and evening, are used continuously 7.
Positive drug group uses Votalin Ointment, smears illing skin, 3 times a day, continuous to smear 7.
Four, efficacy determination
(1) fully recover: knee stiffness and feeling of pain completely disappear, and joint motion restores normal, no arthroncus hydrops, bone
Save loose phenomenon;
(2) effective: knee stiffness and feeling of pain disappear or are obviously improved substantially, and joint motion is unrestricted, substantially unrelated
Save swelling hydrops, joint hypertrophy phenomenon;
(3) effectively: knee stiffness and feeling of pain are improved, and joint motion is slightly limited, can be with slight joint
Swelling hydrops, joint hypertrophy phenomenon;
(4) invalid: knee stiffness and feeling of pain are not improved, even aggravating, joint motion is limited, and running is forced,
It can be with more serious arthroncus hydrops, joint hypertrophy phenomenon.
Five, adverse reaction monitoring
Monitor medication during and medication after in 7 days, excessive internal heat, erythema, the incidence of flush adverse reaction.
Six, test result
After treatment in 7 days, each test group clinical efficacy statistical result is referring to following table.
Each test group clinical efficacy statistical form of table 2
Group | Number of cases | Recovery from illness | It is effective | Effectively | In vain | Total effective rate |
Positive drug group | 60 | 5 | 10 | 34 | 11 | 81.7% |
Example 1 group | 60 | 12 | 19 | 26 | 3 | 95.0% |
1 group of comparative example | 60 | 2 | 7 | 32 | 19 | 68.3% |
2 groups of comparative example | 60 | 2 | 14 | 36 | 8 | 86.7% |
From Table 2, it can be seen that moxibustion plaster of the present invention is to knee stiffness caused by various types arthritis and pain
Treatment total effective rate has reached 95.0%, thus either total effective rate or cure rate is also demonstrate,proved obviously higher than comparative example group
It is real fern fiber crops component is added into moxibustion plaster pack formula to significantly improve its therapeutic effect to anchylosis and pain.
After treatment in 7 days and follow-up in 7 days, each test group adverse reaction statistical result is referring to following table.
Each test group adverse reaction statistical form of table 3
Group | Number of cases | It gets angry | Erythema | Flush | Incidence (%) |
Positive drug group | 60 | 2 | 4 | 5 | 18.3% |
Example 1 group | 60 | 0 | 3 | 10 | 21.7% |
1 group of comparative example | 60 | 7 | 5 | 22 | 56.7% |
2 groups of comparative example | 60 | 1 | 1 | 6 | 13.3% |
From table 3 it is observed that example 1 group and 2 groups of comparative example of adverse reaction rate are significantly lower than comparative example 1
Group, thus illustrate to be added into moxibustion plaster pack formula the chestnut shell powder that prepare through special process facilitate reduction excessive internal heat, erythema,
The generation of the adverse reactions such as flush.
The preferred embodiments of the disclosure and embodiment are explained in detail above, but the present invention is not limited to
The above-described embodiment and examples can also not depart from the present invention within the knowledge of those skilled in the art
Various changes can be made under the premise of design.
Claims (10)
1. a kind of, for warming and activating meridian, the long-acting moxibustion plaster of damp dispelling and pain relieving, it is made of pack and heating pack, and the pack is glutinous
It is attached in the heating pack and long-acting moxibustion plaster is made, it is characterised in that:
The pack is made of the raw material of following weight parts:
Chen Ai 85-92, rhizoma zingiberis 2.5-3.0, fern fiber crops 3.5-5.0,
Chestnut shell 2.0-2.5, raw green salt 1.2-1.6, shallot root base of a fruit 1.2-1.6,
Wormwood essential oil 0.1-0.8;
The heating pack is made of fever miberal powder.
2. long-acting moxibustion plaster as described in claim 1, it is characterised in that wherein the pack is made through following step:
(1) by Chen Ai, rhizoma zingiberis, raw green salt and the shallot root base of a fruit are dry, mix, smash it through 80 meshes, obtain mixed powder;
(2) fern fiber crops clean dry is placed on frying 30 minutes in 120-125 DEG C of frying pan, is crushed after cooling, crossed 80 meshes and obtain
To fern fiber crops powder;
(3) chestnut shell clean dry is placed in 200-220 DEG C of frying pan and is continuously fried to carbonization, crushed after cooling,
It crosses 80 meshes and obtains chestnut shell powder;
(4) above-mentioned mixed powder, fern fiber crops powder and chestnut shell powder are mixed, it slowly is added in wormwood essential oil after mixing evenly
In, it is ground when being added, until becoming flowing water shape fine grained powder mixture, gained flowing water shape fine grained powder mixture is packed into nothing
In woven fabric bag to get arrive the pack.
3. long-acting moxibustion plaster as described in claim 1, wherein the parts by weight of each raw material of the pack, which are made, is:
Chen Ai 90, rhizoma zingiberis 2.8, fern fiber crops 4.5,
Chestnut shell 2.4, raw green salt 1.5, the shallot root base of a fruit 1.5,
Wormwood essential oil 0.5.
4. long-acting moxibustion plaster as described in claim 1, it is characterised in that the raw material that the pack is made further includes following weight
Part:
5. long-acting moxibustion plaster as claimed in claim 4, it is characterised in that the raw material that the pack is made further includes following weight
Part:
Myrrh 0.8-1.2, root of Dahurain angelica 0.5-0.6, caulis akebiae 0.3-0.4,
Bat's faces 0.3-0.4, raw excrementum pteropi 0.5-0.6.
6. long-acting moxibustion plaster as described in claim 1, it is characterised in that the raw material that the pack is made further includes following weight
Part:
7. long-acting moxibustion plaster as described in claim 1, it is characterised in that the raw material that the pack is made further includes following weight
Part:
Bamboo vinegar 2.0-2.5, bamboo charcoal 1.2-1.6, conchiolin powder 1.0-1.2,
Ascorbic acid 0.2-0.3, campanulaceae root extract 0.5-0.8.
8. long-acting moxibustion plaster as described in claim 1, it is characterised in that the raw material that the pack is made further includes following weight
Part: camomile extract 2.5-3.0.
9. such as application of the described in any item long-acting moxibustion plasters of claim 1-8 in preparation external application damp dispelling and pain relieving drug.
10. as the described in any item long-acting moxibustion plasters of claim 1-8 preparation treatment palace cold, dysmenorrhea, neurasthenia, insomnia,
In headache, stomachache, constipation, diarrhea, abdominal pain, flu, infantile convulsion, hypertension, diabetes, eye strain or weight-reducing external drug
Application.
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Cited By (3)
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CN111329756A (en) * | 2020-04-30 | 2020-06-26 | 江西源生狼和药业有限公司 | A method for extracting moxibustion rod containing folium Artemisiae Argyi |
CN111672022A (en) * | 2020-06-10 | 2020-09-18 | 上海市嘉定区中心医院(上海健康医学院附属嘉定区中心医院、上海交通大学医学院附属仁济医院嘉定分院) | Application of moxibustion patch combined with artificial feeding in preparation of medicine for restoring intestinal function |
CN116712324A (en) * | 2023-04-27 | 2023-09-08 | 云南郑保制药有限公司 | Notoginseng moxibustion plaster |
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CN111329756A (en) * | 2020-04-30 | 2020-06-26 | 江西源生狼和药业有限公司 | A method for extracting moxibustion rod containing folium Artemisiae Argyi |
CN111672022A (en) * | 2020-06-10 | 2020-09-18 | 上海市嘉定区中心医院(上海健康医学院附属嘉定区中心医院、上海交通大学医学院附属仁济医院嘉定分院) | Application of moxibustion patch combined with artificial feeding in preparation of medicine for restoring intestinal function |
CN116712324A (en) * | 2023-04-27 | 2023-09-08 | 云南郑保制药有限公司 | Notoginseng moxibustion plaster |
CN116712324B (en) * | 2023-04-27 | 2024-04-23 | 云南郑保制药有限公司 | Notoginseng moxibustion plaster |
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