CN1067579C

CN1067579C - Medicine for curing tumor and its preparation method

Info

Publication number: CN1067579C
Application number: CN98112881A
Authority: CN
Inventors: 张继宏
Original assignee: Individual
Current assignee: Individual
Priority date: 1998-06-01
Filing date: 1998-06-01
Publication date: 2001-06-27
Anticipated expiration: 2018-06-01
Also published as: CN1237429A

Abstract

The present invention relates to a medicine for treating tumor, cancer radio-resistance and enhancing the immune function and a making method thereof. The present invention has the purpose of adjusting physical irritability, enhancing immunity, enhancing disease prevention and treatment capability and promoting rehabilitation. The present invention is composed of clam (quality) elements, laminaria, shiitake fungus, astragalus root and radix salviae miltiorrhizae. The process method comprises the steps that the materials are respectively pretreated; a powdered article is obtained via decoction, filtration, concentration and drying; the product is formed by the proportioning. The present invention has the advantages of tumor resistance, tumor development control and reduction, immunity strengthening, life quality improvement, radiation damage prevention, safety and no toxicity, the product is a bioactivity product.

Description

A kind of medicine for the treatment of tumor

The present invention relates to treat tumor, treatment cancer, radioprotective, improve a kind of Chinese medicine of immunologic function and preparation method thereof, refer in particular to a kind of medicine for the treatment of tumor.

In background technology, in the Chinese invention patent communique, disclose on March 5th, 1997 a kind of " Sanzhu Body Resistance Strengthening and Anticancer Oral Liquid and preparation method thereof ", its technology is to comprise three strain bacterium basal liquids, adds the medicinal herb components Radix Astragali, Radix Rehmanniae Preparata, Radix Codonopsis, Ganoderma, Herba Rabdosiae Lophanthoidis, Radix Scutellariae, Folium Eriobotryae, Rhizoma Phragmitis, Rhizoma Paridis, Colla Corii Asini, Cutis Bufonis, Bombyx Batryticatus, Limax, Scorpio, Scolopendra, Gekko Swinhonis.It carries out grafting production according to microecology, threpsology and Chinese medicine and pharmacy with bionic technology, and its effect is strengthening the body resistance, detoxicating and resolving stagnation of pathogens, the pain relieving of reducing phlegm, auxiliary for treating cancer, performance efficacy of anti-cancer.On March 25th, 1998 is in Gazette of Patent for Invention, " a kind of Chinese medicine-cancer for the treatment of cancer must restrain " disclosed, its Chinese medicine adopts Huang Shi, Radix Ginseng, Cornu Cervi, Gekko Swinhonis, Scorpio, spends in vain, Herba Hedyotidis Diffusae, Carapax et Plastrum Testudinis, Radix Notoginseng, Rhizoma Curcumae, Radix Arnebiae (Radix Lithospermi), rhizoma sparganic, Concha Ostreae, Sargassum, Sal Ammoniacus are formed, and its function is hard masses softening and resolving, blood circulation promoting and blood stasis dispelling, strengthening vital QI to eliminate pathogenic factors, heat-clearing and toxic substances removing, invigorating the spleen and regulating the stomach.Above-mentioned treatment Chinese medicine all is made up of and process different prescriptions, has his own strong points.

The objective of the invention is basis clinical experience for many years, development " a kind of medicine for the treatment of tumor ",

Be intended in the antineoplastic Comprehensive Treatment, adjust physical stress, enhancing immunity, the ability of raising disease preventing and treating promotes rehabilitation.

Technical solution of the present invention is as follows:

It forms percentage by weight:

Freshwater mussel (matter) element: 49～51%, Thallus Laminariae (Thallus Eckloniae): 19～21%, Lentinus Edodes: 8～12%,

The Radix Astragali: 9-11%, Radix Salviae Miltiorrhizae: 9.5～10.5%;

The production method of making the medicine for treating tumor thing is as follows:

Get its powder by the percentage by weight of above-mentioned composition,, get 0.5 gram, make compound capsule, through being up to the standards for a then through the proportioning mixing.

Technical solution of the present invention also comprises:

The preparation technology that freshwater mussel (matter) is plain:

1. raw material is handled: fish for Unionidae animal cristaria plicata-fresh water mussel, in the storage pond, holding pond, get rid of the body dirt, scrub and peel off, get its whole soft tissue, discard moisture content, put into blendor and rub, put into homogenizer again and grind to form tissue homogenate;

2. anticorrosion: tissue homogenate (being slurry) is put into agitator, and adding weight is 0.2% sodium benzoate solution, fully stirring and evenly mixing;

3. acid adjustment degree: in the homogenate after preservative treatment, low add the hydrochloric acid solution of concentration 36%, add while stirring, when being transferred to PH=4.0 till, semi-finished product;

4. purify: get above-mentioned semi-finished product and put into container, drip the ethanol volume ratio 1 of concentration 60%: 0.5-0.8 slowly, after stirring, use filtered through gauze, get its filtrate;

5. separate: with filtrate centrifugation, centrifugal rotational speed is 3000 rev/mins, continues 20 minutes, and ethanol is reclaimed in the precipitation distillation then, takes out lower floor's solids, dries up, drains;

6. dry: as to place 50 ℃ of constant temperature dry down the separator of semi-wet, make powdery freshwater mussel (matter) element.

Be respectively to preparation technology's method of Thallus Laminariae (Thallus Eckloniae), Lentinus Edodes, the Radix Astragali and Radix Salviae Miltiorrhizae below:

1. raw material is handled: remove impurity is cleaned and is dried;

2. pulverize and soak: after pulverizing, shredding, put into container, be soaked in water, stir, soaked even 1～8 hour;

3. decoction filtering: take out the ground product after soaking, full with water logging, decocted 8～12 hours, temperature through its filtrate of leaching, is got its juice through pushing residue at 80 ℃～100 ℃;

4. concentrate: filtrate filtered and juice are condensed into thick liquid;

5. dry: the thick liquid after will concentrating is in 50 ℃ of dry down oven dry of constant temperature, and porphyrize sieves, and gets the powdery semi-finished product.Get its powder by the percentage by weight of above-mentioned composition,, make compound capsule through the proportioning mixing.

Embodiments of the invention are described as follows: one, prepare raw material earlier:

Preparation freshwater mussel (matter) element: get fresh water or the sea water mussel that lives, one about 3～6 ages, 0.1～1.5kg is heavy, and in the storage pond, holding pond, the filling clear water in an about week, makes freshwater mussel get rid of harmful substance in the substance; Reap again in the flowing water pond, brush away the outer dirt of shell, rive with cutter and take out whole soft tissue, abandon that its moisture content puts into that the strand cutter rubs or be subzero homogenate again after freezing 3～5 hours, put into refiner and grind to form tissue homogenate in temperature.Preservative treatment: get mussel homogenate 50kg, add weight and be 0.2% sodium benzoate, fully stirring and evenly mixing; Slowly the hydrochloric acid that adds concentration 36%, stirring and evenly mixing, be transferred to acidity PH=4.0, stock stand-byly for semi-finished product, get its semi-finished product 25kg, drip concentration 60% ethanol volume ratio 1: 0.5～0.8 slowly, stumble evenly with the blender strand, the reuse double gauze filters, and measures filtrate PH=4.0, until be adjusted to requirement; Filtrate is put to centrifuge, do centrifugation, rotating speed is 3000 rev/mins, rotates 20 minutes, leave standstill, redistillation reclaims ethanol, and siphon removes upper strata ethanol liquid, takes out lower floor's solids, dry up or drain moisture content with infrared equipment with pressure regulating equipment, place baking oven again, freeze-day with constant temperature promptly gets powdery freshwater mussel element.

Identical with the Radix Salviae Miltiorrhizae method for making for Thallus Laminariae (Thallus Eckloniae) (being Thallus Laminariae (Thallus Eckloniae)), Lentinus Edodes, the Radix Astragali, promptly raw material is handled: remove roguing soil and substandard products, with chipper or pulverizer chopping, pulverize raw material, be soaked in water then, following 2 hours of room temperature, and stir frequently, put into pot again and decoct, about 80～100 ℃ of temperature was boiled 8～12 hours, limit leaching filtrate again, the extruding residue is got its juice, and vacuum decompression is condensed into thick liquid again, dry oven dry under 50 ℃ of constant temperature, sieve with the dismembyator porphyrize, get powder raw material.Two, preparation finished product: get powder raw material:

Get above-mentioned 6 groups of powders, the proportioning mixing is a compound capsule with 0.5 gram, is that a plate is that three plates are a box with 10, promptly gets this product.

Advantage of the present invention and effect are as follows:

1. the mechanism of anti-curing oncoma of the present invention is controlled the development that slows down tumour exactly, and reinforced immunological power changes Kind quality of life; Pre-antiradiation injury. Flavour of a drug of the present invention are few, and its composition pharmacology is described as follows:

The freshwater mussel element: the yellowish or yellow powder for preparing from the soft tissue of fresh water freshwater mussel exactly has and can strengthen Immunity function, radioresistance, the effect such as antitumor.

Kelp: be the dry thallus of Laminariaceae plant sea-tangle or Alariaceae plant kelp, this product is curling folding Become bulk, or tangle into handle, all be pitchy or green and brown look, the surface is the leaf of bandlet shape with bloom Sheet, the gas raw meat, it is salty to distinguish the flavor of, and has reducing blood lipid, step-down, antitumor, anti-radiation, atherosclerosis etc. Effect.

Mushroom: be Basidiomycotina, Hymenomycetes, Agaricales, Agaricaceae, Lentinus aquatic foods/do umbrella in fact Body (cap, stem). Wherein contain the polysaccharide cancer-resisting substances such as 1.3-beta-glucosidase, can improve the people The immune function of body is the activator of the strongest helper lymphocyte T known today, and it can sting Swash antibody and form, activated macrophage, thereby but the growth of inhibition cancer cell, the nucleotides that it is contained, tool Reducing blood lipid, hypotensive activity are arranged. Contain in the mushroom and induce human interferon's material, the inducer of its interferon, To treating viral illness and tumour very important value is arranged.

The Radix Astragali: the dry root that is legume astragalus mongolicus or Astragalus membranacus. Gas is little, and it is little sweet to distinguish the flavor of, and that chews is little Beany flavor is arranged, and astragalus polyose has many-sided active, and is to tumour, hepatitis, angiocardiopathy, all anti-ageing Certain curative effect is arranged.

2. composition of the present invention and preparation technology make its composition increased activity, are a kind of good biological regulations Agent, balance the body metabolism and endocrine, human activin irritability is set upright reinforcing, and complex treatment is gone out The cancer cell of living is suppressed tumour cell. From traditional treatment " combat poison with poison " different, the production worker who has The skill temperature and pressure is too high, and its composition activity is greatly affected.

3. pass through preliminary test, this product is biological active product, and safety non-toxic strengthens immunity, radioresistance, Improve the ability of disease preventing and treating, promote rehabilitation, suppress to reduce leucocyte.

4. not only flavour of a drug are few for this product, and mouthfeel is good, and have obvious town to ache pain relieving for the middle and advanced stage tumor patient Effect, this product make effectively stable coordination of human nerve-endocrine-Immune Regulative Network, will keep body Dynamic equilibrium realizes " healthy tendency internal memory, heresy can not be done ", drives evilly in the hope of reaching to set upright, attack and just do not hinder, This is characteristics of the present invention places.

Claims

1, a kind of medicine for the treatment of tumor is characterized in that: its composition percentage by weight is:

The Radix Astragali: 9～11%, Radix Salviae Miltiorrhizae: 9.5～10.5%; Its preparation method is as follows: the preparation technology that freshwater mussel (matter) is plain:

1. raw material is handled: fish for Unionidae animal cristaria plicata-fresh water mussel, in the storage pond, holding pond, get rid of the body dirt, scrub and peel off, get its whole soft tissue, discard moisture content, put into stricture of vagina and cut device and rub, put into homogenizer again and grind to form tissue homogenate;

1. raw material is handled: remove impurity is cleaned and is dried;

2. pulverize and soak: after pulverizing, shredding, put into container, be soaked in water, stir, soaked even 1～3 hour;

4. concentrate: filtrate filtered and juice are condensed into thick liquid:

5. dry: the thick liquid after will concentrating is in 50 ℃ of dry down oven dry of constant temperature, and porphyrize sieves, and gets the powdery semi-finished product; Get its powder by the percentage by weight of above-mentioned composition,, make compound capsule through the proportioning mixing.