CN106729307A - One kind treats anginal pharmaceutical formulation - Google Patents

One kind treats anginal pharmaceutical formulation Download PDF

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Publication number
CN106729307A
CN106729307A CN201611164605.XA CN201611164605A CN106729307A CN 106729307 A CN106729307 A CN 106729307A CN 201611164605 A CN201611164605 A CN 201611164605A CN 106729307 A CN106729307 A CN 106729307A
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pharmaceutical formulation
treatment
fruit
course
radix
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张君德
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236—Ligusticum (licorice-root)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258—Panax (ginseng)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286—Carthamus (distaff thistle)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/36—Caryophyllaceae (Pink family), e.g. babysbreath or soapwort
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/40—Cornaceae (Dogwood family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/46—Eucommiaceae (Eucommia family), e.g. hardy rubber tree
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481—Astragalus (milkvetch)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484—Glycyrrhiza (licorice)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537—Salvia (sage)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/57—Magnoliaceae (Magnolia family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A61K36/638—Ligustrum, e.g. Chinese privet
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704—Polygonum, e.g. knotweed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
    • A61K36/725—Ziziphus, e.g. jujube
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/752—Citrus, e.g. lime, orange or lemon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/79—Schisandraceae (Schisandra family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8968—Ophiopogon (Lilyturf)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8969—Polygonatum (Solomon's seal)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/906—Zingiberaceae (Ginger family)
    • A61K36/9064—Amomum, e.g. round cardamom

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
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  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
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  • Veterinary Medicine (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

Anginal pharmaceutical formulation is treated the invention discloses one kind, is by weight to include following traditional Chinese medicine ingredients：The 28g of the Radix Astragali 15, radix pseudostellariae 15 28g, tuber of dwarf lilyturf 16g, the fruit of Chinese magnoliavine 6 13g, red sage root 16g, Ligusticum wallichii 16g, safflower 16g, bark of eucommia 10g, vine of multiflower knotweed 10g, Fructus Corni 10g, fruit of glossy privet 16g, radix polygonati officinalis 13g, pseudo-ginseng 16g, dried orange peel 13g, fructus amomi 6g, honey-fried licorice root 6g.The preparation and application of Chinese medicine composition of the present invention：It is decocted in water for oral dose：Daily 1 dose, 7 doses be a course for the treatment of, it is necessary to the course for the treatment of of medication 26.

Description

One kind treats anginal pharmaceutical formulation
Technical field
It is to be related to one kind to treat anginal pharmaceutical formulation specifically the invention belongs to Chinese medicine composition.
Background technology
Angina pectoris refer to because coronary atherosclerosis cause coronary insufficiency, myocardium ischemia with With precordialgia as main clinical manifestation one group of syndrome caused by anoxic.Its feature is the shirtfront squeezing property of paroxysmal Sensation of pain, can be with other symptoms, and pain is predominantly located at breastbone rear portion, can be radiated to pareordia and left upper extremity, often betides When working or be excited, last for several minutes is rested or is disappeared with after nitrate preparations.This disease is more common in male, most patients It is tired, excited more than 40 years old, it to be satiated with food, catches cold, rainy weather, acute circulatory failure etc. is common inducement.The property heart Angina should squeeze to tighten, compressing asphyxia, and heavy vexed swollen property pain is frequently located in breastbone or its is neighbouring outside tract pain or discomfort, May also occur at upper abdomen to any level between pharyngeal.Risk factor is secondly excited based on physical fatigue, is stepped on Building, level land skelps, and exposed to cold environment, enters cold drink, the pain at other positions of body, and terrified, anxiety, gets angry, and is tired of The emotional change such as angry, can all induce.Symptom being treated Western medicine, it is impossible to effectively treat the disease, and utilize Chinese herbal treatment, with peace more Entirely, effective advantage.
The present invention is used to treat the pharmaceutical formulation of angina pectoris nursing, for angina pectoris etiology and pathogenesis, with clearing heat and detoxicating, heat-clearing Dampness removing, cleaning heat and expelling wind, restore menstrual flow and invigorate blood circulation, promoting circulation of blood detumescence, promoting blood circulation to remove blood stasis, dissipating bind dredging collateral be the rules for the treatment of, reach cold dispelling Wen Yang, promote blood circulation only Bitterly, anginal effect is treated.
The content of the invention
Present invention aim to address the problem in prior art, spy provide a kind of effect substantially, the course for the treatment of is shorter controls Treat anginal pharmaceutical formulation.
In order to realize foregoing invention purpose, the present invention is made the raw material composition and its weight proportion of the effective ingredient For：Radix Astragali 15-28g, radix pseudostellariae 15-28g, tuber of dwarf lilyturf 16g, fruit of Chinese magnoliavine 6-13g, red sage root 16g, Ligusticum wallichii 16g, safflower 16g, the bark of eucommia 10g, vine of multiflower knotweed 10g, Fructus Corni 10g, fruit of glossy privet 16g, radix polygonati officinalis 13g, pseudo-ginseng 16g, dried orange peel 13g, fructus amomi 6g, honey-fried licorice root 6g.This The preparation and application of invention Chinese medicine composition：It is decocted in water for oral dose：Daily 1 dose, 7 doses be a course for the treatment of, it is necessary to the medication 2-6 courses for the treatment of.
Invent for treating anginal pharmaceutical formulation, natural drug is selected, for angina pectoris etiology and pathogenesis, ingredients Respectively have its effect, coordinate mutually, radix pseudostellariae in side, the tuber of dwarf lilyturf, the fruit of Chinese magnoliavine have the effect that Yiqi and vein recovery promotes the production of body fluid.Radix Astragali tonifying Qi good medicine；Process sweet Careless bushing QI invigorating coordinating the drug actions of a prescription bark of eucommia temperature male wind-supplying kidney；Vine of multiflower knotweed liver-kidney tonifying, strengthening the essence benefit blood；The flat filling liver kidney negative and positive of Fructus Corni；Female Loyal sub main bowl spares, five viscera settling supports spirit, except hundred diseases；Dried orange peel, fructus amomi strengthening the spleen and stomach qi-regulating, make benefit without stagnant.Above-mentioned all herbal medicines Share, mutually collaboration bring out the best in each other, play altogether clearing heat and detoxicating, clearing heat and promoting diuresis, cleaning heat and expelling wind, restore menstrual flow and invigorate blood circulation, promoting circulation of blood detumescence, Huoxue San " The effect of the stasis of blood, dissipating bind dredging collateral, reaches the work of stasis of blood blood, and unobstructed vessel, phlegm network leads to, and treats anginal effect.
Specific embodiment
Embodiment 1：One kind treats anginal pharmaceutical formulation, by weight including following traditional Chinese medicine ingredients：Radix Astragali 15- 28g, radix pseudostellariae 15-28g, tuber of dwarf lilyturf 16g, fruit of Chinese magnoliavine 6-13g, red sage root 16g, Ligusticum wallichii 16g, safflower 16g, bark of eucommia 10g, the vine of multiflower knotweed 10g, Fructus Corni 10g, fruit of glossy privet 16g, radix polygonati officinalis 13g, pseudo-ginseng 16g, dried orange peel 13g, fructus amomi 6g, honey-fried licorice root 6g.
Embodiment 2：If patient's insomnia, the vine of multiflower knotweed increases to 28g, spina date seed 13g in said components.
It is decocted in water for oral dose：Daily 1 dose, 7 doses be a course for the treatment of, it is necessary to the medication 2-6 courses for the treatment of.
The clinical therapeutic efficacy of the pharmaceutical formulation for angina pectoris nursing of the present invention is illustrated below by way of practical example.
1st, clinical data
50 patient with angina pectoris, patient's average age 45 ± 20 years old (25~65 years old), meet "《Chinese medical disease Standardization of diagnosis and curative effect》 Angina diagnostic criteria in (State Administration of Traditional Chinese Medicine's promulgation) ", full diagnostics is patient with angina pectoris.
50 patient with angina pectoris all have the symptoms such as pectoralgia, cardiac arrhythmia, heart failure.
Criterion of therapeutical effect
Cure：Clinical symptom disappearance, cardiac muscle detection is normal；
It is effective：Clinical symptoms substantially mitigate, and patient's rhythm of the heart is neat, painless；
It is invalid：Clinical symptoms are without substantially mitigation, exacerbation of symptoms, and it is invalid to be judged to.
3rd, treatment results
After 50 patient with angina pectoris treat 3~4 courses for the treatment of, cure 38, treat effective 8, invalid 2.Treating total effective rate is 93%.
Typical case：
Chen, man, 66 years old.Because of precordialgia 2 years after activity, exacerbation is admitted to hospital for 2 months.Patient started appearance during upper 4 floor before 2 years Precordialgia, in vexed pain, aches with left upper extremity, and tens seconds to 1 minute are continued every time, and rest about l/min can be alleviated, every month Breaking-out 1~2 time.Started before 2 months firmly, it is excited when there is precordial fullness bitterly, last up to 10 minutes, with cold sweat, head Confused, weak, while there is whole left upper extremity to ache or uncomfortable, precordialgia is broken out, is disappeared simultaneously with left upper extremity pain, sometimes left Upper extremity pain first sends out l~2 minute compared with precordialgia, through rest or buccal " suxiao jiuxin pills " or " sorbitrate tablet " 3~5 minutes Can alleviate, break out every month 5~6 times.There is hyperpiesia history 10 years, controlling of blood pressure is unknown, treatment by Chinese herbs is determined afterwards. 6 doses of inventive formulation is taken, is decocted in water for oral dose, daily 1 dose, daily 3 clothes.Second examines：Spinning sensation substantially mitigates, 12 doses of following the service, and three examine： Pain elementary solution is removed, and is after treatment effect afterwards, is advised and is continued to take 12 doses.Follow-up 1 year, all goes well.

Claims (3)

1. one kind treats anginal pharmaceutical formulation, it is characterised in that：The pharmaceutical formulation by weight include following Chinese medicine into Point：Radix Astragali 15-28g, radix pseudostellariae 15-28g, tuber of dwarf lilyturf 16g, fruit of Chinese magnoliavine 6-13g, red sage root 16g, Ligusticum wallichii 16g, safflower 16g, the bark of eucommia 10g, vine of multiflower knotweed 10g, Fructus Corni 10g, fruit of glossy privet 16g, radix polygonati officinalis 13g, pseudo-ginseng 16g, dried orange peel 13g, fructus amomi 6g, honey-fried licorice root 6g.
2. anginal pharmaceutical formulation is treated as claimed in claim 1, it is characterised in that：The pharmaceutical formulation also includes the vine of multiflower knotweed Increase to 28g, spina date seed 13g.
3. the preparation and application of Chinese medicine composition of the present invention：It is decocted in water for oral dose：Daily 1 dose, 7 doses be a course for the treatment of, it is necessary to medication 2-6 The course for the treatment of.
CN201611164605.XA 2016-12-16 2016-12-16 One kind treats anginal pharmaceutical formulation Withdrawn CN106729307A (en)

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Application Number Priority Date Filing Date Title
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Application publication date: 20170531