CN105983053B - A Chinese medicinal composition for treating cardiovascular and cerebrovascular diseases, and its preparation method - Google Patents

A Chinese medicinal composition for treating cardiovascular and cerebrovascular diseases, and its preparation method Download PDF

Info

Publication number
CN105983053B
CN105983053B CN201610194427.9A CN201610194427A CN105983053B CN 105983053 B CN105983053 B CN 105983053B CN 201610194427 A CN201610194427 A CN 201610194427A CN 105983053 B CN105983053 B CN 105983053B
Authority
CN
China
Prior art keywords
parts
radix
cerebrovascular diseases
treating cardiovascular
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201610194427.9A
Other languages
Chinese (zh)
Other versions
CN105983053A (en
Inventor
郭学忠
赵焕英
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CN201610194427.9A priority Critical patent/CN105983053B/en
Publication of CN105983053A publication Critical patent/CN105983053A/en
Application granted granted Critical
Publication of CN105983053B publication Critical patent/CN105983053B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/60Moraceae (Mulberry family), e.g. breadfruit or fig
    • A61K36/605Morus (mulberry)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236Ligusticum (licorice-root)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284Atractylodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286Carthamus (distaff thistle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/34Campanulaceae (Bellflower family)
    • A61K36/344Codonopsis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/46Eucommiaceae (Eucommia family), e.g. hardy rubber tree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/488Pueraria (kudzu)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537Salvia (sage)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/65Paeoniaceae (Peony family), e.g. Chinese peony
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/752Citrus, e.g. lime, orange or lemon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8968Ophiopogon (Lilyturf)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention belongs to the field of traditional Chinese medicine pharmacy, and discloses a medicine for preventing, improving and treating cardiovascular and cerebrovascular diseases and a preparation method thereof, wherein the medicine comprises the following raw materials: radix Salviae Miltiorrhizae, radix Codonopsis, rhizoma Chuanxiong, ramulus Mori, flos Carthami, radix Puerariae, cortex Eucommiae, radix Paeoniae Rubra, rhizoma Atractylodis, radix Ophiopogonis, and pericarpium Citri Reticulatae. The medicament of the invention has wide clinical application, quick response and obvious treatment effect.

Description

A Chinese medicinal composition for treating cardiovascular and cerebrovascular diseases, and its preparation method
Technical Field
The invention belongs to the field of traditional Chinese medicines, and relates to a medicine for preventing, improving and treating cardiovascular and cerebrovascular diseases.
Background
With the continuous improvement of life of people, cardiovascular and cerebrovascular diseases become common clinical diseases, and patients with hypertension and hyperlipidemia are seen everywhere and seriously threaten the health and life of human beings. At present, western medicines are mainly clinically applied to treat more, and serious patients need surgical treatment, such as cardiac stents and cardiac bypass surgery. Although the western medicine has good effect, the western medicine has great damage to the human body after long-term administration, has certain side effect, higher operation treatment cost and certain danger, and can cause great trauma to the human body.
The invention aims to overcome the problems in the prior art and provide a safe and low-cost traditional Chinese medicine preparation, a preparation method and application thereof, so that the traditional Chinese medicine preparation can effectively prevent blood coagulation, dilate blood vessels, improve blood circulation, reduce blood fat and stabilize blood pressure.
Disclosure of Invention
The invention aims to provide a medicinal composition for preventing, improving and treating cardiovascular and cerebrovascular diseases, which has the advantages of quick response, good effect and no side effect, and a preparation method thereof.
The technical scheme of the invention is as follows: a traditional Chinese medicine composition for treating cardiovascular and cerebrovascular diseases is prepared from 10-15 parts of ramulus mori, 15-25 parts of radix puerariae, 4-6 parts of eucommia ulmoides, 4-6 parts of safflower carthamus, 10-15 parts of radix salviae miltiorrhizae, 6-9 parts of radix paeoniae rubra, 4-6 parts of rhizoma atractylodis, 4-6 parts of radix ophiopogonis, 5-7 parts of pericarpium citri reticulatae, 5-7 parts of ligusticum wallichii and 8-12 parts of codonopsis pilosula.
When in treatment, 5-20 times of water is added according to the weight of the traditional Chinese medicines and the weight of the traditional Chinese medicines, and the traditional Chinese medicines are heated and boiled for 0.2-1 hour to extract a liquid medicine A; adding 5-15 times of water into the medicine residues, heating and boiling for 0.2-1 hour, extracting medicine liquid B, A B and mixing to obtain the medicine.
The medicines are compatible, so that the traditional Chinese medicine composition can effectively prevent blood coagulation, dilate blood vessels, reduce blood fat, improve blood circulation and greatly reduce the blockage of heart and cerebral vessels. The invention has more than ten years of clinical experience, can take the symptoms and root causes into consideration, and has very good effect.
The invention has remarkable curative effect on treating cardiovascular and cerebrovascular diseases through more than ten years of clinical experience, has no toxic or side effect and is not easy to relapse. 100 patients are randomly selected, and the effective rate is up to 96% by follow-up observation.
Detailed Description
Example 1: a Chinese medicinal composition for treating cardiovascular disease and cerebrovascular disease comprises ramulus Mori 10-15 parts, radix Puerariae 15-25 parts, Eucommiae cortex 4-6 parts, Carthami flos 4-6 parts, Saviae Miltiorrhizae radix 10-15 parts, radix Paeoniae Rubra 6-9 parts, rhizoma Atractylodis 4-6 parts, radix Ophiopogonis 4-6 parts, pericarpium Citri Tangerinae 5-7 parts, rhizoma Ligustici Chuanxiong 5-7 parts, radix Codonopsis 8-12 parts
Adding 5-20 times of water into the above medicinal materials, boiling with strong fire, and decocting with slow fire for 0.2-1 hr to obtain medicinal liquid A. Adding 5-15 times of water into the dregs of a decoction, boiling with strong fire, decocting with slow fire for 0.2-1 hour, extracting liquid medicine B, and mixing liquid medicines A B to obtain liquid medicine of medicine C. The treatment is carried out by taking one dose every day, and 15 days are a treatment course.
Example 2: in the embodiment of 1, the liquid medicine of the Chinese medicinal preparation C is extracted and concentrated to a proper amount or dried to form dry paste, and a proper amount of auxiliary materials are added, so that the dry paste can be prepared into granules or pressed into tablets.
Example 3: the present example is a clinical case:
① A certain woman 54 years old Wuan city is suffered from paroxysmal pain before heart for 4-5 years, the paroxysm is interrupted, each pain is about 20 minutes, sometimes the paroxysm is 1 hour or half day, the whole body sweats and cannot move when the pain occurs, most of the paroxysms are in the process of cooking or are dry, active and urgent, the patient is treated in Wuan city hospital for a plurality of times in 2010, the unstable angina is diagnosed, the treatment is performed by dipyridamole, pain relieving and the like, the traditional Chinese medicine treatment is started in our hospital from 3 months in 2011, western medicines are stopped, the patient can work slightly after 10 days, the electrocardiogram is changed obviously, the medicine is continuously used for half a year, and the angina is not generated so far.
② A certain man, 48 years old, Wuan city, Wujian mountain village, is diagnosed with paroxysmal neck and back discomfort for 5-6 years, the patient has been diagnosed with coronary atherosclerotic heart disease and unstable angina pectoris in 2009 and 2011 twice in the first hospital due to neck and back discomfort, but the patient still has two obstructed coronary arteries, such as the right coronary artery, and fails to implant a stent, western medicines are maintained, and the patient is discharged in 2011 at 12 months.
③ A certain female 71-year-old small Wancun Wuan city, patients suffered from precordial oppression and asthma paroxysmal attack in 2011 and treated in a municipal hospital, symptoms aggravated in 2013 in 12 months, precordial pain appeared, and many attacks after physical exertion sometimes can be relieved by themselves after rest, and the patients received traditional Chinese medicine treatment in 2014 in 2 months, symptoms basically disappear after one month, can slightly move, continue to take medicine for half a year, and have no discomfort until now.
④ Su is that in 2011, a patient is diagnosed with coronary heart disease and angina pectoris in three departments, namely a Chinese chenchen and chen Tai, and two supports are implanted, so that in 2013, the patient receives traditional Chinese medicine treatment because of symptom aggravation, the pain and the discomfort in the precordial area disappear after 20 days, and the patient continues to use the medicine for half a year, and no pain or discomfort occurs until the phone follow-up visit.

Claims (3)

1. A traditional Chinese medicine composition for treating cardiovascular and cerebrovascular diseases is characterized by comprising the following raw materials: 10-15 parts of mulberry twig, 15-25 parts of kudzuvine root, 4-6 parts of eucommia bark, 4-6 parts of safflower, 10-15 parts of red sage root, 6-9 parts of red paeony root, 4-6 parts of rhizoma atractylodis, 4-6 parts of dwarf lilyturf tuber, 5-7 parts of tangerine peel, 5-7 parts of szechuan lovage rhizome and 8-12 parts of pilose asiabell root.
2. The use of the Chinese medicinal composition of claim 1 in the preparation of medicaments for preventing and treating cardiovascular and cerebrovascular diseases.
3. The Chinese medicinal composition of claim 1, wherein the dosage form is granules or tablets.
CN201610194427.9A 2016-03-31 2016-03-31 A Chinese medicinal composition for treating cardiovascular and cerebrovascular diseases, and its preparation method Active CN105983053B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201610194427.9A CN105983053B (en) 2016-03-31 2016-03-31 A Chinese medicinal composition for treating cardiovascular and cerebrovascular diseases, and its preparation method

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201610194427.9A CN105983053B (en) 2016-03-31 2016-03-31 A Chinese medicinal composition for treating cardiovascular and cerebrovascular diseases, and its preparation method

Publications (2)

Publication Number Publication Date
CN105983053A CN105983053A (en) 2016-10-05
CN105983053B true CN105983053B (en) 2020-07-14

Family

ID=57044590

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201610194427.9A Active CN105983053B (en) 2016-03-31 2016-03-31 A Chinese medicinal composition for treating cardiovascular and cerebrovascular diseases, and its preparation method

Country Status (1)

Country Link
CN (1) CN105983053B (en)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008112561A1 (en) * 2007-03-09 2008-09-18 Pfantastic Medical Research Institute, Llc Combination therapy for alleviating pain-related conditions

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
"辨证分型治疗脑梗死68例疗效观察";杨丽阳;《中国中医急症》;20050228;第14卷(第2期);第108-109页 *
杨丽阳."辨证分型治疗脑梗死68例疗效观察".《中国中医急症》.2005,第14卷(第2期),第108-109页. *

Also Published As

Publication number Publication date
CN105983053A (en) 2016-10-05

Similar Documents

Publication Publication Date Title
CN100382839C (en) Chinese-medicinal composition for treating coronary heart disease
CN101011522B (en) Chinese traditional medicine for treating cardiopathy
CN103041336B (en) Traditional Chinese medicine composition for treating coronary heart disease
CN101433689A (en) Kudzu root and longstamen onion bulb oral liquid and preparation method
CN102133288B (en) Chinese herbal preparation for curing angina
CN100455313C (en) Chinese medicine for treating cardiovascular and cerebrovascular disease
CN100488558C (en) Medicament for treating heart disease and preparation process thereof
CN105983053B (en) A Chinese medicinal composition for treating cardiovascular and cerebrovascular diseases, and its preparation method
CN102908425A (en) Medicine for treating heart diseases and thick blood lipid and preparation method of the medicine
CN103212041B (en) Chinese medicinal composition treating coronary heart disease
CN102366466A (en) Traditional Chinese medicine footbath agent for treating dermatophytosis
CN105749216A (en) Traditional Chinese medicine wine for treating hypertension and preparation method thereof
CN105435196A (en) Externally-applied traditional Chinese medicine ointment for treating qi stagnation and blood stasis coronary angina pectoris with chronic gastritis and preparation method thereof
CN104117018A (en) Traditional Chinese medicine composition for treating coronary heart disease
CN104474015A (en) Medicine for lowering blood pressure and blood fat and preparation method of medicine
CN101983712A (en) Novel medicament for treating coronary heart disease
CN102552724A (en) Chinese medicine composite for curing hypertension
CN107693621A (en) Chinese medicine and its preparation for coronary heart disease myocardial infarction treatment
CN101658661A (en) Chinese medicinal composition having effect of promoting blood circulation and removing blood stasis
CN100406054C (en) Chinese-medicinal preparation for treating hypertension and preventing lesion
CN106620531A (en) Traditional Chinese medicine composition for treating amenorrhea
CN105079394A (en) Pharmaceutic preparation for treating arrhythmia
CN105343688A (en) Medicine composition for treating myocardial infarction and application thereof
CN105079768A (en) Traditional Chinese medicine composition for treating coronary heart disease caused by syndrome of phlegm obstruction
CN104771739A (en) Traditional Chinese medicine composition for treating climacteric syndrome

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant