CN106728325A - It is a kind of to treat Chinese medicine preparation of coronary heart disease and preparation method thereof - Google Patents

It is a kind of to treat Chinese medicine preparation of coronary heart disease and preparation method thereof Download PDF

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Publication number
CN106728325A
CN106728325A CN201611166602.XA CN201611166602A CN106728325A CN 106728325 A CN106728325 A CN 106728325A CN 201611166602 A CN201611166602 A CN 201611166602A CN 106728325 A CN106728325 A CN 106728325A
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chinese medicine
medicine preparation
heart disease
coronary heart
radix
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李中海
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/21—Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/233—Bupleurum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236—Ligusticum (licorice-root)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258—Panax (ginseng)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286—Carthamus (distaff thistle)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/34—Campanulaceae (Bellflower family)
    • A61K36/346—Platycodon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/42—Cucurbitaceae (Cucumber family)
    • A61K36/428—Trichosanthes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481—Astragalus (milkvetch)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/482—Cassia, e.g. golden shower tree
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484—Glycyrrhiza (licorice)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/68—Plantaginaceae (Plantain Family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/734—Crataegus (hawthorn)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/752—Citrus, e.g. lime, orange or lemon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/80—Scrophulariaceae (Figwort family)
    • A61K36/804—Rehmannia

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Abstract

By weight it is to include following traditional Chinese medicine ingredients the invention discloses a kind of Chinese medicine preparation for treating coronary heart disease：Radix Astragali 30g, Fructus Aurantii 13g, balloonflower root 13g, safflower 13g, peach kernel 13g, radix paeoniae rubrathe 13g, Ligusticum wallichii 13g, radix bupleuri 13g, root of bidentate achyranthes 13g, Radix Angelicae Sinensis 13g, radix rehmanniae recen 13g, licorice 13g, cassia twig 15g.The preparation and application of Chinese medicine composition of the present invention：It is decocted in water for oral dose：Daily 1 dose, 7 doses be a course for the treatment of, it is necessary to the course for the treatment of of medication 26.

Description

It is a kind of to treat Chinese medicine preparation of coronary heart disease and preparation method thereof
Technical field
It is to be related to a kind of Chinese medicine preparation for treating coronary heart disease specifically the invention belongs to Chinese medicine composition.
Background technology
Coronary heart disease full name coronary atherosclerotic heart disease, refers to because lipid-metabolism is abnormal, the lipid in blood Calmness on the endarterium of otherwise smooth, in endarterium, pile up and form white patch by some similar athero- lipid materials, Referred to as atherosclerotic lesion.These patches increase and cause lumen of artery narrow gradually, blood flow is obstructed, and cause heart ischemia, Produce angina pectoris.The Etiological of coronary heart disease is coronary atherosclerosis, but not completely clear the reason for atherosclerosis Chu, it may be possible to the result of many factors comprehensive function.Think that this pathogenetic hazards has：Age and sex（More than 45 years old Male, more than 55 years old or postclimacteric women）, family history（Before 55 years old, mother/sister died from father and elder brothers before 65 years old Heart disease）, dyslipidemia (LDL-C is too high, and HDL-C is too low), hypertension, glucose in urine Disease, smoking is overweight, fat, and gout is not moved.Symptom being treated Western medicine, it is impossible to effectively treat the disease, and utilize Chinese herbal medicine more Treatment, with safe and effective advantage.
The present invention is used to treat the Chinese medicine preparation of coronary heart disease nursing, for the coronary heart disease cause interpretation of the cause, onset and process of an illness, with clearing heat and detoxicating, heat-clearing Dampness removing, cleaning heat and expelling wind, restore menstrual flow and invigorate blood circulation, promoting circulation of blood detumescence, promoting blood circulation to remove blood stasis, dissipating bind dredging collateral be the rules for the treatment of, reach cold dispelling Wen Yang, promote blood circulation only Bitterly, effect of coronary heart disease is treated.
The content of the invention
Present invention aim to address the problem in prior art, spy provide a kind of effect substantially, the course for the treatment of is shorter controls Treat the Chinese medicine preparation of coronary heart disease.
In order to realize foregoing invention purpose, the present invention is made the raw material composition and its weight proportion of the effective ingredient For：Radix Astragali 30g, Fructus Aurantii 13g, balloonflower root 13g, safflower 13g, peach kernel 13g, radix paeoniae rubrathe 13g, Ligusticum wallichii 13g, radix bupleuri 13g, root of bidentate achyranthes 13g, when Return 13g, radix rehmanniae recen 13g, licorice 13g, cassia twig 15g.The preparation and application of Chinese medicine composition of the present invention：It is decocted in water for oral dose：Often It 1 dose, 7 doses be a course for the treatment of, it is necessary to the medication 2-6 courses for the treatment of.
The Chinese medicine preparation for treating coronary heart disease is invented, natural drug is selected, for the coronary heart disease cause interpretation of the cause, onset and process of an illness, ingredients Respectively have its effect, coordinate mutually, peach kernel, safflower, Ligusticum wallichii, radix paeoniae rubrathe removing blood stasis and promoting blood circulation, Radix Angelicae Sinensis, radix rehmanniae recen blood circulation promoting nourishes blood, radix bupleuri, Fructus Aurantii reason Gas is soothing the liver, and the root of bidentate achyranthes stimulates the menstrual flow broken stasis of blood, and balloonflower root enters lung channel, and Radix Glycyrrhizae emergency leads to hundred arteries and veins with coordinating the drug actions of a prescription, and the cassia twig temperature heart activates yang.It is above-mentioned all Herbal medicine share, mutually collaboration bring out the best in each other, play altogether clearing heat and detoxicating, clearing heat and promoting diuresis, cleaning heat and expelling wind, restore menstrual flow and invigorate blood circulation, promoting circulation of blood detumescence, The effect of promoting blood circulation to remove blood stasis, dissipating bind dredging collateral, reaches the work of stasis of blood blood, and unobstructed vessel, phlegm network leads to, and treats effect of coronary heart disease.
Specific embodiment
Embodiment 1：A kind of Chinese medicine preparation for treating coronary heart disease, by weight including following traditional Chinese medicine ingredients：The Radix Astragali 30g, Fructus Aurantii 13g, balloonflower root 13g, safflower 13g, peach kernel 13g, radix paeoniae rubrathe 13g, Ligusticum wallichii 13g, radix bupleuri 13g, root of bidentate achyranthes 13g, Radix Angelicae Sinensis 13g, Radix rehmanniae recen 13g, licorice 13g, cassia twig 15g.
Embodiment 2：If patient there are hyperlipidemic conditions, charred FRUCTUS CRATAEGI 16g, cassia seed 16g are added in said components.
Embodiment 3：If patient's had palpitation symptom, with American Ginseng 13g in said components.
Embodiment 4：If patient has constipation symptom, add in said components and fry Snakegourd Fruit 18g.
Embodiment 5：If patient has double lower limb edematous condition, plantain seed 28g is added in said components.
It is decocted in water for oral dose：Daily 1 dose, 7 doses be a course for the treatment of, it is necessary to the medication 2-6 courses for the treatment of.
The clinical therapeutic efficacy of the Chinese medicine preparation for coronary heart disease nursing of the present invention is illustrated below by way of practical example.
1st, clinical data
50 patients with coronary heart disease, patient's average age 45 ± 20 years old (25~65 years old), meet "《Chinese medical disease Standardization of diagnosis and curative effect》 Diagnostic criteria for coronary heart disease in (State Administration of Traditional Chinese Medicine's promulgation) ", full diagnostics is patients with coronary heart disease.
50 patients with coronary heart disease all have the symptoms such as pectoralgia, cardiac arrhythmia, heart failure.
Criterion of therapeutical effect
Cure：Clinical symptom disappearance, cardiac muscle detection is normal；
It is effective：Clinical symptoms substantially mitigate, and patient's rhythm of the heart is neat, painless；
It is invalid：Clinical symptoms are without substantially mitigation, exacerbation of symptoms, and it is invalid to be judged to.
3rd, treatment results
After 50 courses for the treatment of of Treatment in Patients with Coronary Heart 3~4, cure 38, treat effective 8, invalid 2.Treating total effective rate is 93%.
Typical case：
Lee, male, 54 years old, main suit burst palpitaition, uncomfortable in chest, shortness of breath, in advance without there is palpitaition and chest suddenly under obvious inducement With sweaing all over when vexed, shortness of breath, breaking-out, there is dizzy, dim eyesight, there is spinning sensation, there is weakness of limbs sense, with Nausea and vomiting, vomiting Thing is gastric content, coffee-like, with cough, without heating, chilly, without the dead sense of substantially frequency, without tear sample pain, without nocturnal paroxysmal Expiratory dyspnea, without stomachache, diarrhoea, without falling down, sleeping not good enough without convulsions, diet, development is normal, and nutrition is medium, sanity, and two just Non Apparent Abnormality.Electrocardio is illustrated：Bradycardia, AIMI.6 doses of inventive formulation is taken afterwards, is decocted in water for oral dose, often It 1 dose, daily 3 clothes.Second examines：Spinning sensation substantially mitigates, 12 doses of following the service, and three examine：Pain elementary solution is removed, and afterwards, is controlled to consolidate Therapeutic effect, advises and continues to take 12 doses.Follow-up 1 year, all goes well.

Claims (5)

1. a kind of Chinese medicine preparation for treating coronary heart disease, it is characterised in that：The Chinese medicine preparation by weight include following Chinese medicine into Point：Radix Astragali 30g, Fructus Aurantii 13g, balloonflower root 13g, safflower 13g, peach kernel 13g, radix paeoniae rubrathe 13g, Ligusticum wallichii 13g, radix bupleuri 13g, root of bidentate achyranthes 13g, when Return 13g, radix rehmanniae recen 13g, licorice 13g, cassia twig 15g.
2. the Chinese medicine preparation of coronary heart disease is treated as claimed in claim 1, it is characterised in that：The Chinese medicine preparation also includes charred FRUCTUS CRATAEGI 16g, cassia seed 16g.
3. the Chinese medicine preparation of coronary heart disease is treated as claimed in claim 1, it is characterised in that：The Chinese medicine preparation also includes American Ginseng 13g。
4. the Chinese medicine preparation of coronary heart disease is treated as claimed in claim 1, it is characterised in that：The Chinese medicine preparation also includes frying Snakegourd Fruit 18g。
5. the Chinese medicine preparation of coronary heart disease is treated as claimed in claim 1, it is characterised in that：The Chinese medicine preparation also includes plantain seed 28g。
CN201611166602.XA 2016-12-16 2016-12-16 It is a kind of to treat Chinese medicine preparation of coronary heart disease and preparation method thereof Withdrawn CN106728325A (en)

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