CN106728559A - 一种木瓜平肝和胃含片及其生产方法 - Google Patents
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Abstract
一种木瓜平肝和胃含片及其生产方法。由木瓜、莲须、薄荷、石菖蒲、白石榴花、千针万线草、千斤拔、荠菜、羧甲基纤维素、
水溶性淀粉、
葡萄糖
等原料构成，经过选料、烘干、煎煮、混合、制粉、压片、包装制成成品。
本发明将中药中的有效成分煎煮制成提取液，将有效成分与含片相结合，有效的保留的中药中的营养物质；经过科学的配比，使本发明产品对人体滋补时，具有补而不燥，营养结构合理，增强人体体质的功效。本发明
具有
保健、平肝和胃、纯天然、无污染、无毒无副作用、方便服用并且滋补身体等优点。
Description
技术领域：
本发明涉及食品保健领域，具体涉及一种木瓜平肝和胃含片及其生产方法。
背景技术
口含片指含于口腔内缓慢溶解的压制片，含片从内到外都要有诱人的色、香、味，以使服用者有好的口感。因此，含片中的赋形成分，如糖、色素添加剂等往往“喧宾夺主”，以致一些人误将含片看作是“糖”。
目前，市场上的含片大多数都是药品，而且大多数是治疗咽喉部疾病的药品，适用范围窄，治疗效果一般。而利用含片技术加工制成保健品的利用率少，对人体保健功效少，不能满足市场需求。
发明内容：
本发明的目的在于提供一种集平肝和胃、纯天然、无污染、
无毒无副作用于一体，方便服用并且滋补身体
的木瓜平肝和胃含片及生产方法。
本发明的目的是这样实现的。它是由下述重量配的原料制成的，
木瓜
15-30
份、莲须
10-20
份、薄荷
5-15
份、石菖蒲
3-15
份、白石榴花
3-15
份、千针万线草
3-10
份、千斤拔
4-12
份、荠菜
6-9
份、羧甲基纤维素
7-10
份、水溶性淀粉
4-8
份、葡萄糖
10-15
份。
制备本发明木瓜平肝和胃含片优选重量配比范围是，
木瓜
15-25
份、莲须
10-15
份、薄荷
5-12
份、石菖蒲
3-10
份、白石榴花
3-10
份、千针万线草
3-8
份、千斤拔
4-10
份、荠菜
6-8
份、羧甲基纤维素
7-9
份、水溶性淀粉
4-7
份、葡萄糖
10-14
份。
制备本发明木瓜平肝和胃含片最佳重量配比范围是，
木瓜
20
份、莲须
12
份、薄荷
10
份、石菖蒲
8
份、白石榴花
8
份、千针万线草
5
份、千斤拔
8
份、荠菜
7
份、羧甲基纤维素
8
份、水溶性淀粉
6
份、葡萄糖
12
份。
将上述各组份制成本发明木瓜平肝和胃含片的生产方法，主要工艺流程为：选料、烘干、煎煮、混合、制粉、压片、包装，具体操作方法依次按下列步骤：
A
、选料、按原料重量配比，挑选符合国家卫生和质量标准的木瓜、莲须、薄荷、石菖蒲、白石榴花、千针万线草、千斤拔、荠菜、羧甲基纤维素、
水溶性淀粉、
葡萄糖原料备用；
B
、烘干、除羧甲基纤维素、
水溶性淀粉、
葡萄糖外，其他原料分别切成块状或片状置于烘干箱中干化，温度控制在
80-100
℃，时间
45
分钟，使原料水份蒸发至含水量
18%
，压片；
C
、煎煮、按上述重量份数比，将烘干后的原料添加置煎煮器中煎煮
2
次，第一次加
7
倍水量煎煮
1.5
小时，第二次架
5
倍水量煎煮
1
小时，分别过滤提取滤液，将两次滤液合并，二次过滤药渣和杂质，制得提取液；
D
、混合、按上述重量份数比，将提取液中加入羧甲基纤维素、水溶性淀粉、葡萄糖充分混合均匀，制得混合液；
E
、制粉、将上述混合液的滤液冷却至室温，利用喷雾干燥法将滤液制成混合粉，备用；
F
、压片、将上述混合粉除去生产过程中的产生的杂质，然后利用辐射压片的方式和紫外线压片方式压片；压片后利用压片机直接压片；
G
、包装、将上述压合好的片剂按照销售规格包装。
本发明将对人体有良好滋补效果的中药成分与含片相结合，相比现有的含片具有更好的吸收效果，方便人们平时服用，调理人体健康，增加体内新陈代谢平衡，调节人体体内平衡更加柔和，提升体质更加平缓，可长时间有效的对人体增加动力和工作耐力。
本发明将中药中的有效成分煎煮制成提取液，将有效成分与含片相结合，有效的保留的中药中的营养物质；经过科学的配比，使本发明产品对人体滋补时，具有补而不燥，营养结构合理，增强人体体质的功效。
本发明配方中，木瓜平肝和胃，去湿舒筋；治吐泻转筋，湿痹，脚气，水肿，痢疾；莲须固肾涩精，用于遗精滑精，带下，尿频；
薄荷疏风，散热，辟秽，解毒；治外感风热，头痛，目赤，咽喉肿痛，食滞气胀，口疮，牙痛，疮疥，瘾疹；石菖蒲化湿开胃，开窍豁痰，醒神益智；用于脘痞不饥，噤口下痢，神昏癫痫，健忘耳聋；白石榴花涩肠止血；主久痢；便血；咳血；衄血；吐血；千针万线草健脾养血；补肝益肾；消肿；主贫血；精神短少；头晕心慌；耳鸣眼花；潮热；遗精；月经不调；带下；骨折；乳腺炎；千斤拔祛风利湿，消瘀解毒；治风湿痹痛，慢性肾炎，跌打损伤，痈肿，喉蛾；
荠菜和脾，利水，止血，明目；治痢疾，水肿，淋病，乳糜尿，吐血，便血，血崩，月经过多，目赤疼痛
。
本发明在经过多例患者的服用与临床验证，不断总结和完善，配方比较完整，疗效确切，对吐泻转筋，湿痹，脚气
等主
病
证：程度不同起到了
平肝和胃，去湿舒筋
的作用，
具有
保健、平肝和胃、纯天然、无污染、无毒无副作用等优点。
本发明经两组临床验证,其中一组为治疗组服用本发明含片，每天服用一次，7天为一个疗程，另一组对照服用“康恩贝”，
每天服用一次，7天为一个疗程，每组选择门诊病人200例，其中男100例，女100例，量大年龄74
岁，最小
年龄28
岁，
临床表现为吐泻转筋，湿痹，脚气，水肿，痢疾
，外感风热，头痛，目赤，咽喉肿痛，食滞气胀
，表一为服用一个疗程后的对照数据：
表
1
服用前后两组疗程比较
(
单位
:
人
)
治疗组和对照组有显著差异，从而可以看出本发明在临床上的应用有显著的疗效。
本发明的工艺优点在于：1、选择原料和配方科学，生产工艺先进，其产品产口味良好，方便存放；2、产品中不含防腐剂等有害成分，保持原料对人体的滋补和营养成份，易被人体吸收；3、原料来源广泛，加工艺线路短，产品易加工制造。
具体实施方式
下面结合具体实施例对本发明作进一步的说明
实施例1：适用于吐泻转筋，湿痹，脚气
的人群
制备本发明木瓜平肝和胃含片是由下列组份原料制成的（用量为重量份），
木瓜
15-30
份、莲须
10-20
份、薄荷
5-15
份、石菖蒲
3-15
份、白石榴花
3-15
份、千针万线草
3-10
份、千斤拔
4-12
份、荠菜
6-9
份、羧甲基纤维素
7-10
份、水溶性淀粉
4-8
份、葡萄糖
10-15
份。
实施例2：适用于水肿，痢疾
，外感风热，头痛
的人群
制备本发明木瓜平肝和胃含片优选重量配比范围是：
木瓜
15-25
份、莲须
10-15
份、薄荷
5-12
份、石菖蒲
3-10
份、白石榴花
3-10
份、千针万线草
3-8
份、千斤拔
4-10
份、荠菜
6-8
份、羧甲基纤维素
7-9
份、水溶性淀粉
4-7
份、葡萄糖
10-14
份。
实施例
3
：适用于
目赤，咽喉肿痛，食滞气胀
的人群
制备本发明木瓜平肝和胃含片最佳重量配比范围是，木瓜20份、莲须12份、薄荷10份、石菖蒲8份、白石榴花8份、千针万线草5份、千斤拔8份、荠菜7份、羧甲基纤维素8份、水溶性淀粉6份、葡萄糖12份。
实施例4
将上述各组份制成本发明木瓜平肝和胃含片的生产方法，主要工艺流程为：选料、烘干、煎煮、混合、制粉、压片、包装，具体操作方法依次按下列步骤：
A
、选料、按原料重量配比，挑选符合国家卫生和质量标准的木瓜、莲须、薄荷、石菖蒲、白石榴花、千针万线草、千斤拔、荠菜、羧甲基纤维素、
水溶性淀粉、
葡萄糖原料备用；
B
、烘干、除羧甲基纤维素、
水溶性淀粉、
葡萄糖外，其他原料分别切成块状或片状置于烘干箱中干化，温度控制在
80-100
℃，时间
45
分钟，使原料水份蒸发至含水量
18%
，压片；
C
、煎煮、按上述重量份数比，将烘干后的原料添加置煎煮器中煎煮
2
次，第一次加
7
倍水量煎煮
1.5
小时，第二次架
5
倍水量煎煮
1
小时，分别过滤提取滤液，将两次滤液合并，二次过滤药渣和杂质，制得提取液；
D
、混合、按上述重量份数比，将提取液中加入羧甲基纤维素、水溶性淀粉、葡萄糖充分混合均匀，制得混合液；
E
、制粉、将上述混合液的滤液冷却至室温，利用喷雾干燥法将滤液制成混合粉，备用；
F
、压片、将上述混合粉除去生产过程中的产生的杂质，然后利用辐射压片的方式和紫外线压片方式压片；压片后利用压片机直接压片；
G
、包装、将上述压合好的片剂按照销售规格包装。
实施例
2
在含片的处方中如果加入适量崩解剂如
CMS-Na
改善含片稳定性，或者加入蔗糖粉、甘露醇、山梨醇、各种甜味剂、香精等调和口感。
Claims (4)
1.一种木瓜平肝和胃含片，其特征在于：它是由下述重量配比的原料制成的，木瓜15-30份、莲须10-20份、薄荷5-15份、石菖蒲3-15份、白石榴花3-15份、千针万线草3-10份、千斤拔4-12份、荠菜6-9份、羧甲基纤维素7-10份、水溶性淀粉4-8份、葡萄糖10-15份。
2.根据权利要求1所述的一种木瓜平肝和胃含片，其特征在于：其中各种原料的重量配比是，木瓜15-25份、莲须10-15份、薄荷5-12份、石菖蒲3-10份、白石榴花3-10份、千针万线草3-8份、千斤拔4-10份、荠菜6-8份、羧甲基纤维素7-9份、水溶性淀粉4-7份、葡萄糖10-14份。
3.根据权利要求1所述的一种木瓜平肝和胃含片，其特征在于：其中各种原料的重量配比是，木瓜20份、莲须12份、薄荷10份、石菖蒲8份、白石榴花8份、千针万线草5份、千斤拔8份、荠菜7份、羧甲基纤维素8份、水溶性淀粉6份、葡萄糖12份。
4.根据权利要求1-3所述的木瓜平肝和胃含片的生产方法，其特征在于：主要工艺流程为：选料、烘干、煎煮、混合、制粉、压片、包装，具体操作方法依次按下列步骤：
A、选料、按原料重量配比，挑选符合国家卫生和质量标准的木瓜、莲须、薄荷、石菖蒲、白石榴花、千针万线草、千斤拔、荠菜、羧甲基纤维素、水溶性淀粉、葡萄糖原料备用；
B、烘干、除羧甲基纤维素、水溶性淀粉、葡萄糖外，其他原料分别切成块状或片状置于烘干箱中干化，温度控制在80-100℃，时间45分钟，使原料水份蒸发至含水量18%，压片；
C、煎煮、按上述重量份数比，将烘干后的原料添加置煎煮器中煎煮2次，第一次加7倍水量煎煮1.5小时，第二次架5倍水量煎煮1小时，分别过滤提取滤液，将两次滤液合并，二次过滤药渣和杂质，制得提取液；
D、混合、按上述重量份数比，将提取液中加入羧甲基纤维素、水溶性淀粉、葡萄糖充分混合均匀，制得混合液；
E、制粉、将上述混合液的滤液冷却至室温，利用喷雾干燥法将滤液制成混合粉，备用；
F、压片、将上述混合粉除去生产过程中的产生的杂质，然后利用辐射压片的方式和紫外线压片方式压片；压片后利用压片机直接压片；
G、包装、将上述压合好的片剂按照销售规格包装。
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008031095A (ja) * | 2006-07-28 | 2008-02-14 | Kao Corp | Ｓｃｆ結合阻害剤 |
| CN104815203A (zh) * | 2015-04-20 | 2015-08-05 | 韩萍 | 一种治疗三叉神经痛的中药配方 |
| CN104940780A (zh) * | 2014-03-24 | 2015-09-30 | 哈尔滨浩拓生物科技开发有限公司 | 一种草河车健胃止泻冲剂及生产方法 |
-
2015
- 2015-11-24 CN CN201510820301.3A patent/CN106728559A/zh active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008031095A (ja) * | 2006-07-28 | 2008-02-14 | Kao Corp | Ｓｃｆ結合阻害剤 |
| CN104940780A (zh) * | 2014-03-24 | 2015-09-30 | 哈尔滨浩拓生物科技开发有限公司 | 一种草河车健胃止泻冲剂及生产方法 |
| CN104815203A (zh) * | 2015-04-20 | 2015-08-05 | 韩萍 | 一种治疗三叉神经痛的中药配方 |
Non-Patent Citations (1)
| Title |
|---|
| 胡郁坤等: "《袖珍中药应用速查手册（插图本）》", 31 July 2012, 湖南科学技术出版社 * |
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