CN106728347B - 一种风湿液及其制备方法 - Google Patents

一种风湿液及其制备方法 Download PDF

Info

Publication number
CN106728347B
CN106728347B CN201611032511.7A CN201611032511A CN106728347B CN 106728347 B CN106728347 B CN 106728347B CN 201611032511 A CN201611032511 A CN 201611032511A CN 106728347 B CN106728347 B CN 106728347B
Authority
CN
China
Prior art keywords
component
rheumatism
filtering
preparation
leaching
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201611032511.7A
Other languages
English (en)
Other versions
CN106728347A (zh
Inventor
魏聆
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shaanxi Tiansen Biological Engineering Technology Co. Ltd.
Original Assignee
Shaanxi Tiansen Biological Engineering Technology Co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shaanxi Tiansen Biological Engineering Technology Co ltd filed Critical Shaanxi Tiansen Biological Engineering Technology Co ltd
Priority to CN201611032511.7A priority Critical patent/CN106728347B/zh
Publication of CN106728347A publication Critical patent/CN106728347A/zh
Application granted granted Critical
Publication of CN106728347B publication Critical patent/CN106728347B/zh
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286Carthamus (distaff thistle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/47Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/54Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/57Magnoliaceae (Magnolia family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/83Thymelaeaceae (Mezereum family), e.g. leatherwood or false ohelo
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/51Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/53Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

Abstract

本发明公开了一种风湿液及其制备方法,将辣椒、独活、黑蜂蜂房、黑蚂蚁、天青地红、红花和狼毒,经二次醇提浓缩后,加入肉桂油,经静置、过滤后得到风湿液,本发明采用纯天然中药材形成的配方,具有祛风除湿,活血通络之效。用于外邪侵袭经络,气血闭阻不畅,引起关节、肢体等处出现酸、麻、肿、痛及屈伸不利等症状,且剂型简单,使用方便,可有效治疗各种风湿疾病。本发明制备工艺简单,对设备要求低,环境友好,适合工业化放大生产。

Description

一种风湿液及其制备方法
技术领域
本发明涉及一种中药涂擦剂,特别涉及一种风湿液及其制备方法。
背景技术
风湿病由流行病调查与循证确认为常见病、多发病,且缠绵难愈。带给患者的是无止尽的苦不堪言的病痛折磨。风湿病是一种慢性疾病,此病虽不致命,发作起来却肿痛难忍,严重影响患者的工作和生活,降低了生命质量,目前还没有很好的治疗方法。最新研究表明,风湿病的患病率随着年龄的增大而逐渐升高,男性患病率低于女性,相对寒冷的地区和相对潮湿的沿海地区患病率较高。随着中国社会老龄化程度加深,未来几年将是中国风湿病高发时期。
目前,市面上常见的抗风湿药物,其主要成分以非甾体类抗炎药、类固醇激素口服药等居多,非甾体类抗炎药对胃刺激作用大,类固醇激素长期应用副作用较大,因此综合考虑药效、毒副作用方面,亟需一种天然纯中药的副作用较小的外用液体制剂。
发明内容
本发明的目的在于提供一种风湿液及其制备方法。
为达到上述目的,本发明采用了以下技术方案:
一种风湿液,该液体包括组分A以及组分B,所述组分A由50~200g辣椒、50~200g独活、50~200g蜂房、50~100g黑蚂蚁、20~50g天青地红、20~50g红花以及20~50g狼毒制成,所述组分B为20~50g肉桂油。
优选的,所述组分A由50~100g辣椒、50~100g独活、50~100g蜂房、50~100g黑蚂蚁、20~50g天青地红、20~50g红花以及20~50g狼毒制成,所述组分B为20~50g肉桂油。
优选的,所述组分A由80g辣椒、50g独活、50g蜂房、50g黑蚂蚁、30g天青地红、20g红花以及20g狼毒制成,所述组分B为25g肉桂油。
优选的,所述组分A为采用醇提浓缩法制成的液体,体积为990~1100mL。
优选的,所述蜂房选自蜜蜂蜂房,例如黑蜂(Apis laboriosa Smith)
辣椒符合药典标准,是辣椒的干燥成熟果实,不需要炮制。
上述风湿液的制备方法,包括以下步骤:
将辣椒、独活、蜂房、黑蚂蚁、天青地红、红花以及狼毒用醇提法制得浸提液,将浸提液浓缩得到组分A,将组分B与组分A混合均匀后依次经静置、过滤,得所述风湿液。
所述风湿液的制备方法,具体包括以下步骤:
1)将50~200g辣椒、50~200g独活、50~200g蜂房、50~100g黑蚂蚁、20~50g天青地红、20~50g红花以及20~50g狼毒用5~10倍质量的质量分数50~80%的乙醇水溶液浸提若干次,每次浸提结束后进行过滤,收集每次过滤得到的滤液作为浸提液,将浸提液减压浓缩至990~1100mL,得浓缩液,浓缩液冷却后即为组分A;
2)将20~50g肉桂油加入组分A,搅拌至充分溶解,然后静置12~48小时,静置后进行过滤,得到所述风湿液。
优选的,所述浸提为两次,第一次浸提包括以下步骤:加入所述乙醇水溶液后先于0~30℃冷浸24~48h,然后加热回流1~3h,然后冷却至常温,冷却后过滤得到滤液A;第二次浸提包括以下步骤:向分离滤液A后的滤渣中加入所述乙醇水溶液,然后加热回流1~3h,然后冷却至常温,冷却后过滤得到滤液B;所述浸提液由滤液A、B合并得到。
优选的,所述乙醇水溶液的质量分数为75%。
优选的,所述第一次浸提中,冷浸的时间为24h,冷浸后加热回流3h;第二次浸提中,加入所述乙醇水溶液后加热回流3h。
与现有技术相比,本发明具有以下有益的技术效果:
本发明所述风湿液是根据民间传世验方,依据祖国传统医药学理论,采用现代科学实验研究方法和先进的制剂技术,经多年潜心钻研,研制开发出的具有良好效果的产品。本产品属液体剂型,直接涂擦于不适处,使用简单方便,是用于改善风寒湿痹,特别改善关节、肢体等处酸、麻、肿、痛及屈伸不利等症状。具有祛风除湿,活血通络之功效。本产品为外用涂擦剂型,直接作用于不适处,吸收快。相对于传统风湿病药物,如非甾体类抗炎药、类固醇激素等,无肠胃刺激,无服用西药的毒副作用,作用可靠。
本发明以辣椒、独活、蜂房、黑蚂蚁、天青地红、红花以及狼毒的醇提浓缩液添加肉桂油制成液体,具有制备工艺简单,对设备要求低,环境友好,适合工业化放大生产的优点。
具体实施方式
下面结合实施例对本发明做进一步的详细说明,所述是对本发明的解释而不是限定。
本发明提供一种风湿液,依据组方命名为黑蜂蚁独液。
(一)组方依据以及制备工艺
中医认为风寒湿痹,为行(风)痹、痛(寒)痹、著(湿)痹的合称。因风寒湿三气杂至,致气血瘀滞,证见身重而痛,四肢拘挛,甚则走注疼痛,或手足麻木等。是外邪侵袭经络,气血闭阻不畅,引起关节、肢体等处出现酸、麻、肿、痛及屈伸不利等症状,名为痹证。治宜温经散寒,祛风除湿,活血通络。本发明采用辣椒、肉桂油、独活、黑蜂蜂房、黑蚂蚁、天青地红、红花、狼毒八味纯天然中药配方,本方中辣椒温中散寒、活血消肿,肉桂油散寒止痛、活血通经,二者同为君药,用于温经散寒,活血消肿。独活,祛风除湿,通痹止痛。用于风寒湿痹,腰膝疼痛。蜂房,攻毒杀虫,祛风止痛。二者同为臣药,用于祛风除湿。红花,活血通经,散瘀止痛。用于跌扑损伤,疮疡肿痛。天青地红,活血通经;散瘀消肿。黑蚂蚁,活血通络,消肿解毒。用于风湿性关节炎,疔毒肿痛。狼毒,散结,杀虫。这四味同为佐药,用于通络止痛。
全方君臣佐配合得当,共奏温经散寒,祛风除湿,活血通络之作用。
(二)配方
Figure GDA0002584006530000031
辅料:75%乙醇(质量分数75%的乙醇水溶液)
(三)制备实例
实例1
(1)将辣椒、独活、黑蜂蜂房、黑蚂蚁、天青地红、红花以及狼毒加入8倍质量60%乙醇中,冷浸24h后加热煮沸,回流3h,然后冷却至常温,过滤。再向滤渣中加入6倍质量60%乙醇,加热煮沸,回流3h,然后冷却至常温,过滤。合并两次滤液,减压浓缩至约1000mL,冷却。
(2)将肉桂油加入步骤1制得的浓缩液中,搅拌至充分溶解。
(3)静置24小时,过滤,成中间品,送检。
(4)灌装(分装10瓶,约100mL/瓶)、外包,成品检验、入库。
实例2
(1)将辣椒、独活、黑蜂蜂房、黑蚂蚁、天青地红、红花以及狼毒加入8倍质量75%乙醇中,冷浸24h后加热煮沸,回流3h,然后冷却至常温,过滤。再向滤渣中加入6倍质量75%乙醇,加热煮沸,回流3h,然后冷却至常温,过滤(两次浸提75%乙醇用量共计4550g)。合并两次滤液,减压浓缩至约1000mL,冷却。
(2)将肉桂油加入步骤1制得的浓缩液中,搅拌至充分溶解。
(3)静置24小时,过滤,成中间品,送检。
(4)灌装(分装10瓶,约100mL/瓶)、外包,成品检验、入库。
实例3
(1)将辣椒、独活、黑蜂蜂房、黑蚂蚁、天青地红、红花以及狼毒加入6倍质量75%乙醇中,冷浸24h后加热煮沸,回流3h,然后冷却至常温,过滤。再向滤渣中加入4倍质量75%乙醇,加热煮沸,回流3h,然后冷却至常温,过滤。合并两次滤液,减压浓缩至约1000mL,冷却。
(2)将肉桂油加入步骤1制得的浓缩液中,搅拌至充分溶解。
(3)静置24小时,过滤,成中间品,送检。
(4)灌装(分装10瓶,约100mL/瓶)、外包,成品检验、入库。
取实例1中提取药渣小样适量用适量75%乙醇提取,浸提液有色,有效成分提取率不高;取实例3中提取药渣小样适量用适量75%乙醇提取,浸提液有色,有效成分提取率不高;取实例2中提取药渣小样适量用适量75%乙醇提取,浸提液几乎无色,有效成分提取率较高。另外,肉桂油在实例2的浓缩液中溶解充分,较实例1和实例3中溶解较好。经过比较,实例2为最佳方案。
(四)用法用量
外用,涂擦不适处,每日1~3次,每次10mL(大约两瓶盖的量),持续使用20天为一个疗程。
(五)病例使用效果
病例1:
赵某某,女,39岁,类风湿8年。8年来双手关节肿胀,疼痛难忍,冬季重夏季轻。数年来多处求医。不减轻反而重,生活不能自理。多次住院治疗,用药:甲氨蝶呤片、强的松片等药。效不显,出院后每日需吃止痛片。使用风湿液一个疗程,疼痛减轻,不需要再服用止痛剂。使用三个疗程,生活基本上可以自理。
总之,本发明所述风湿液采用天然中药配方,能够有效温经散寒,祛风除湿,活血通络。用于外邪侵袭经络,气血闭阻不畅,引起的关节、肢体等处出现酸、麻、肿、痛及屈伸不利等症状,且剂型简单,使用方便,可有效治疗各种风湿疾病,使用安全方便。

Claims (3)

1.一种风湿液的制备方法,其特征在于:包括以下步骤:
将辣椒、独活、蜂房、黑蚂蚁、天青地红、红花以及狼毒用醇提法制得浸提液,将浸提液浓缩得到组分A,将肉桂油与组分A混合均匀后依次经静置、过滤,得所述风湿液;
所述风湿液的制备方法,具体包括以下步骤:
1)将80g辣椒、50g独活、50g蜂房、50g黑蚂蚁、30g天青地红、20g红花以及20g狼毒用质量分数75%的乙醇水溶液浸提两次,第一次75%乙醇水溶液用量为8倍质量,第二次为6倍质量;
第一次浸提包括以下步骤:加入所述乙醇水溶液后先冷浸24h,然后加热煮沸并回流3h,然后冷却至常温;
第二次浸提包括以下步骤:加入所述乙醇水溶液后加热煮沸并回流3h,然后冷却至常温;
每次浸提结束后进行过滤,收集每次过滤得到的滤液作为浸提液,将浸提液减压浓缩至1000mL,得浓缩液,浓缩液冷却后即为组分A;
2)将25g肉桂油加入组分A,搅拌至充分溶解,然后静置24小时,静置后进行过滤,得到所述风湿液。
2.根据权利要求1所述的方法,其特征在于:所述蜂房选自蜜蜂蜂房。
3.一种风湿液,其特征在于:由组分A以及组分B组成,所述组分A由80g辣椒、50g独活、50g蜂房、50g黑蚂蚁、30g天青地红、20g红花以及20g狼毒制成,所述组分B为25g肉桂油。
CN201611032511.7A 2016-11-17 2016-11-17 一种风湿液及其制备方法 Active CN106728347B (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201611032511.7A CN106728347B (zh) 2016-11-17 2016-11-17 一种风湿液及其制备方法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201611032511.7A CN106728347B (zh) 2016-11-17 2016-11-17 一种风湿液及其制备方法

Publications (2)

Publication Number Publication Date
CN106728347A CN106728347A (zh) 2017-05-31
CN106728347B true CN106728347B (zh) 2021-10-26

Family

ID=58971883

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201611032511.7A Active CN106728347B (zh) 2016-11-17 2016-11-17 一种风湿液及其制备方法

Country Status (1)

Country Link
CN (1) CN106728347B (zh)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109045141A (zh) * 2018-10-30 2018-12-21 闫癸江 中药组合物、制剂及应用

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1146343A (zh) * 1995-09-25 1997-04-02 石建民 一种治疗椎间盘病的外敷膏
CN101856426A (zh) * 2010-06-11 2010-10-13 张兆俊 一种治疗风湿性关节炎的药物及其制作方法
CN102274252A (zh) * 2011-08-11 2011-12-14 张晋瑞 治疗类风湿病的野木瓜外用制剂及其制备方法

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1146343A (zh) * 1995-09-25 1997-04-02 石建民 一种治疗椎间盘病的外敷膏
CN101856426A (zh) * 2010-06-11 2010-10-13 张兆俊 一种治疗风湿性关节炎的药物及其制作方法
CN102274252A (zh) * 2011-08-11 2011-12-14 张晋瑞 治疗类风湿病的野木瓜外用制剂及其制备方法

Also Published As

Publication number Publication date
CN106728347A (zh) 2017-05-31

Similar Documents

Publication Publication Date Title
CN106728347B (zh) 一种风湿液及其制备方法
CN104491220A (zh) 一种治疗带状疱疹的中药组合物
WO1999025368A1 (fr) Medicament pour traiter l'algomenorrhee et son procede de preparation
CN101129627A (zh) 一种治疗产后邪毒发热的中药制剂
CN104644889A (zh) 治疗蛇肚疔的外用贴
CN103816399B (zh) 一种用于治疗犬瘟热病的中药制剂
CN106421538A (zh) 一种治疗慢性盆腔炎的中药微型灌肠剂
CN102475852A (zh) 一种治疗颈椎病的中药制剂
CN108310266B (zh) 一种治疗病毒疣的中药
CN102743707B (zh) 治疗急性腰扭伤药丸
CN112691157A (zh) 一种风湿类关节炎药材组合物的配方及制备方法
CN102018912A (zh) 用于治疗急性乳腺炎的中药制剂
CN102188629B (zh) 筋痹外用消痛酊
CN100402079C (zh) 风痛贴膏及其制备方法
CN106902330B (zh) 一种治疗风湿性关节炎、风湿痛的中药制剂及其制备方法和应用
CN105031181A (zh) 一种治疗风湿痹症的药酒及其制备方法
CN104997949A (zh) 一种治疗鼻炎的中药组合物及其制备方法
CN103908542B (zh) 一种治疗类风湿性关节炎的复方制剂及其制备方法
CN105079222A (zh) 一种用于治疗脚气的中药液及其制备方法
CN102100860A (zh) 治疗乳腺炎的中药制剂
CN113599352A (zh) 一种红曲草本膏剂的制备方法及设备
CN112023012A (zh) 治疗痛风的中药组合物及其制备方法和应用
CN105999189A (zh) 一种止血固经中药酒及其制备方法
CN111494592A (zh) 一种中药疗理液
CN108079249A (zh) 一种具有保肝功能的中药制剂及其制备方法

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
TA01 Transfer of patent application right
TA01 Transfer of patent application right

Effective date of registration: 20170905

Address after: 710000 Shaanxi city of Xi'an province Huxian Fengjing Industrial Park Feng four Road No. 2

Applicant after: Shaanxi Tiansen Biological Engineering Technology Co. Ltd.

Address before: 710000 Shaanxi city of Xi'an province Huxian Fengjing Industrial Park Feng Road four

Applicant before: Wei Ling

GR01 Patent grant
GR01 Patent grant