CN106727062A - A kind of antibacterial type washing product and preparation method thereof - Google Patents
A kind of antibacterial type washing product and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a kind of antibacterial type washing product and preparation method thereof, the antibacterial type washing product includes following components：Artemisinin and/or derivative, ZPT（ZPT）, AESA（AESA）, Cocoamidopropyl betaine（CAB）, fatty acid distribution of coconut oil diglycollic amide（CDEA）, Coconut Fatty Acid Monoethanolamide（CMEA）, polyquaternium, guar hydroxypropyltrimonium ammonium chloride, chelating agent, D panthenols, ammonium chloride, solvent.Washing product of the invention has good suppression bacterium, fungi, the effect of virus, while there is good nutrition maintenance function, it is stable in properties, homogeneous.
Description
Technical field
The present invention relates to the technical field of washing product.
Background technology
Many diseases of human body are caused by bacterium, fungi and virus, if can effectively prevent and suppress bacterium, true
Bacterium and the propagation and infection of virus, will greatly reduce human body illness probability, also have the effect for the treatment of to a certain extent.
The antipathogenic composition added in existing antibacterial type washing product generally, part more obvious to the inhibitory action of bacterium
Antipathogenic composition also has good inhibiting effect to fungi, but only a few has the effect for suppressing virus.
Sweet wormwood is composite family artemisia annual herb plant, can be used to treat the diseases such as flu, malaria, the extract tool of sweet wormwood
There is significant antibacterial effect, be a kind of ideal while there is the resistance of highly significant, fungi and the effect of virus is eliminated
Antimicrobial additive.
But Artemisinin or partial derivatives is water-soluble poor, and generally with the compatibility of other antipathogenic compositions compared with
Difference, it is difficult to form the system of stabilization, plays synergy, while can also disturb not between thus can not only making different antipathogenic compositions
The congruent performance of self-acting.
For part needs with good frothing function, with the washing product compared with high viscosity, Artemisinin
Addition can also significantly reduce its foaming and into the effect of cream, cause the washing product to be difficult to be carried out as ripe commodity
City.
The content of the invention
It is an object of the invention to provide a kind of with good suppression bacterium, fungi, virus, while having good battalion
Maintenance function is supported, it is stable in properties, homogeneous, and further there is good foaming effect and the washing product into cream effect, this hair
Bright another object is to provide its preparation method simultaneously.
Technical scheme is as follows：
A kind of antibacterial type washing product, it includes following components：Artemisinin and/or derivative, ZPT（ZPT）,
AESA（AESA）, Cocoamidopropyl betaine（CAB）, fatty acid distribution of coconut oil diglycollic amide
（CDEA）, Coconut Fatty Acid Monoethanolamide（CMEA）, polyquaternium, guar hydroxypropyltrimonium ammonium chloride, chelating agent, D- is general
Alcohol, ammonium chloride, solvent.
The Artemisinin is that the material for obtaining is extracted from sweet wormwood, and its derivative will be extracted from sweet wormwood and obtained
Material carries out the material obtained after certain chemical modification.
Preferably：The Artemisinin includes that the derivative includes one or more in qinghaosu or sweet wormwood wax
One or more in Artesunate, Artemether, arteether, dihydroartemisinine.
Sweet wormwood wax refers to the vegetable wax of sweet wormwood in the preferred scheme.
Artemisinin and/or derivative and ZPT are main antipathogenic composition in above-mentioned technical proposal, and wherein ZPT is to thin
Bacterium and fungi have good killing ability, and Artemisinin and/or derivative have excellent killing energy to fungi, virus
Power, if if both can act synergistically, its corresponding washing product will have good killing bacterium, fungi and disease simultaneously
The effect of poison, can be used as general antibacterial washing product and uses, and also part illness can be treated, and such as be used as shampoo
When, can correct fur capsulitis, favus of the scalp, varicella etc. carry out certain treatment.But both compositions are carrying out simple, direct mixing
Under be difficult to form good com-patibilising effect, thus can interfere the performance of bacteria resistance function each other, bacteria resistance function is more specific herein
For refer to suppress bacterium, fungi, virus function, therefore in the technical program add AESA, CAB, CDEA,
CMEA is to improve compatibility in system of Artemisinin/derivative and ZPT and whole as one of function for entirety
The stability of individual system, while it also has carries out the effect that activity is connected with other compositions, with raising system viscosity
Effect etc..Polyquaternium also has wide spectrum, an efficient bactericidal effect in the system, and with ZPT collective effects, increase antibacterial model
Enclose, while it has good dispersion, osmosis, with it is certain deoil, deodorizing capability and corrosion inhibition, as hair washing
During liquid, hair end bifurcated slightly is repaired with good, improve submissive, the smooth effect of hair quality, in this programme, polyquaternium
Its thickening power is also played, its electric charge corrective action, non-oxidizable and its good water solubility, thus each component between system
Stabilization, homogeneous compatible, between each component can mutual Synergistic, system can form stabilization emulsus lotion and contribute.This
Also known as cation guar gum, it has low deposition and good hair conditioning to guar hydroxypropyltrimonium ammonium chloride in scheme,
On the one hand the nutrition maintenance function of washing product can be strengthened, system toughness on the one hand can be improved, be ensured steady certainly in system
Exist calmly, in addition charge density, intermolecular charge balance of the guar hydroxypropyltrimonium ammonium chloride by its own, can be right
The system of the washing product carries out electric charge adjustment and balance, thereby guarantees that each component can be stablized, equably exist in system.
D-pantothenyl aleohol is also a kind of nutritional ingredient in this programme, and it can promote the metabolism of human body protein, fat, carbohydrate, keep skin and
The moistening of mucous membrane, improves hair luster, stimulates epithelial cell growth, promotes wound healing, an antiinflammation, enhance immunity,
The generation of disease is prevented, hair jag can be also prevented in hair nursing, be damaged, increase the density of hair, improve hair quality gloss；
The hydrability of nail can also be improved in the nursing of nail, nail pliability is assigned.The present invention selects the component, not only because its is good
Good nutrition repair function, at the same also because its can in body series stable existence.Ammonium chloride has thickening power in this programme,
Can improve system into cream effect, while it can adjust the dissolubility of other compositions system Nei, may be used also as strong electrolyte
With the charge balance in adjustment system, and pH to system is adjusted.
Preferably：The antibacterial type washing product also includes component Texapon Special.
The addition of the composition can significantly increase the foaming effect of system, while it can be with the other compositions in system
It is compatible, while promotion system foams, the dissolubility of other compositions or them will not be suppressed play a role in reduction system.
It is also preferred that：The component of the antibacterial type washing product also includes pearling agent（EGDS）, glycerine, silicone oil.
The addition of said components can improve the nutrition repair function of the washing product, while pearling agent has decoration and increases
Thick effect, can further improve system into cream effect, the addition of these three nutriments also can further improve the phase of system
Capacitive and charge balance, thus obtain the system that one kind of multiple nutritional ingredients and they and inhibitory anti-virus stable components coexist.
It is also preferred that：The antibacterial type washing product also includes component hydroxyethyl cellulose.
The component has the spy of good thickening, suspension, dispersion, emulsification, bonding, film forming, protection moisture and protecting colloid
Property, Simultaneous Stabilization emulsus lotion and liquid can be played a part of in system, further improve homogeneous, the stability of system.
It is also preferred that：The antibacterial type washing product also includes following components：Citric acid.
It is also preferred that：The antibacterial type washing product in parts by mass, including following components：Artemisinin and/
Or derivative：0.1 ~ 0.3 part, ZPT：0.3 ~ 0.8 part, AESA：6.7 ~ 7.7 parts, CAB：9.0 ~ 11.0 parts, CDEA：3.2~5.0
Part, CMEA：1.5 ~ 2.0 parts, Polyquaternium-10：1.0 ~ 1.5 parts, guar hydroxypropyltrimonium ammonium chloride：0.1 ~ 0.5 part,
The D-pantothenyl aleohol solution of 50wt%：0.2 ~ 0.4 part, ammonium chloride：0.1 ~ 0.3 part.
In the program and the aftermentioned 50wt% D-pantothenyl aleohol solution refer to D-pantothenyl aleohol the aqueous solution.
It is further preferably：The antibacterial type washing product in parts by mass, also including following components：Lauryl sulphur
Sour ammonium：8.0 ~ 10.0 parts, hydroxyethyl cellulose：0.1 ~ 0.3 part, EGDS：1.3 ~ 2.0 parts, glycerine：It is 1.0 ~ 4.0 parts, water-soluble
Silicone oil：0.1 ~ 0.5 part.
The present invention further discloses a kind of preparation method of antibacterial type washing product, it is comprised the following steps：
Artemisinin and/or derivative are dissolved using organic solvent, and is formulated as the sweet wormwood liquid of 30 ~ 50wt%；
Guar hydroxypropyltrimonium ammonium chloride is formulated as colloidal sol using deionized water；
Polyquaternium is formulated as polyquaternium solution using deionized water；
Dissolved during chelating agent is added into deionized water, obtained chelating agent solution；
CMEA is added after the chelating agent solution is heated up, the first mixed liquor is obtained；
First mixed liquor is vacuumized in a heated state, AESA and CAB is added thereafter, insulation thereafter is 60 ~ 80
DEG C, CDEA, the polyquaternium solution and the colloidal sol are added, homogenization is carried out under keeping warm mode, obtain the second mixing
Liquid；
40 ~ 60 DEG C are cooled to second mixed liquor, the D-pantothenyl aleohol solution and ZPT of 50wt% are added, thereafter under keeping warm mode
Homogenization is carried out, the 3rd mixed liquor is obtained；
3rd mixed liquor is cooled to 20 ~ 40 DEG C, ammonium chloride and the sweet wormwood liquid is added, stood thereafter, obtain the suppression
Bacterial type washing product.
The present invention further discloses the preparation method of another antibacterial type washing product, it is comprised the following steps：
Sweet wormwood Artemisinin and/or derivative are dissolved using organic solvent, and is formulated as the sweet wormwood liquid of 30 ~ 50wt%；
Guar hydroxypropyltrimonium ammonium chloride is formulated as colloidal sol using deionized water；
Polyquaternium is formulated as polyquaternium solution using deionized water；
Food grade colorant is formulated as pigment solution using deionized water；
Dissolved during EDTA ~ 2Na is added into deionized water, obtained chelating agent solution；
After the chelating agent solution is warming up into 85 ~ 90 DEG C, Texapon Special and CMEA are added, obtain the first mixed liquor；
First mixed liquor is vacuumized at 85 ~ 90 DEG C, AESA and CAB is added under stirring thereafter, thereafter
It is 60 ~ 80 DEG C to be incubated, and adds CDEA, EGDS, hydroxyethyl cellulose, the polyquaternium solution and the colloidal sol, in insulation shape
Homogenization is carried out under state, the second mixed liquor is obtained；
40 ~ 60 DEG C are cooled to second mixed liquor, D-pantothenyl aleohol solution, water-soluble silicon oil, glycerine and the ZPT of 50wt% is added,
Thereafter homogenization is carried out under keeping warm mode, the 3rd mixed liquor is obtained；
3rd mixed liquor is cooled to 20 ~ 40 DEG C, the pigment solution is added, add the sweet wormwood liquid, ammonium chloride and
Citric acid, stands afterwards completely to EGDS growing the grains, obtains the antibacterial type washing product.
Further, the materials such as essence, preservative can also be added in above-mentioned steps, its be preferably added mode be
Added in last step for preparing.
A kind of preferred embodiment of above two antibacterial type washing product is：The organic solvent is double de- ethanol and double
The mixture of desacetoxy ethyl ester.
The invention has the advantages that：
（1）Suppress bacterium, fungi, the effect of virus while washing product of the invention has good；
（2）Washing product property of the invention is homogeneous, stabilization, and each component compatibility is good, mutual Synergistic, common adjustment
Balanced with maintenance system；
（3）Comprehensively, particularly thus its certain preferred embodiments makes washing product nutritional ingredient of the invention with more prominent
With good maintenance repair function；
（4）Washing product of the invention can form the emulsus lotion of good stabilization；
（5）Some compositions, such as hydroxyethyl cellulose in the preferred embodiment of washing product of the invention, in emulsus lotion
The combination of moisture and lotion part has good Adjustment effect, thus can further obtain washing for more stable emulsus lotion formula
Shield articles for use；
（6）Washing product of the invention has good foaming effect；
（7）Preparation method of the invention can obtain homogeneous, the stable product of property, and each component is compatible in maximizing product
Property, and the Synergistic between giving full play to the effect of each component and promoting them；
（8）Preparation method of the invention can improve the apparent effect of product simultaneously, improve consumer's favorable rating.
Specific embodiment
Below by way of specific embodiment, the present invention is described in further detail, but this should not be interpreted as into the present invention
Scope be only limitted to following example.In the case where above method thought of the present invention is not departed from, according to ordinary skill
Various replacements or change that knowledge and customary means are made, should be included in the scope of the present invention.
Embodiment 1
Be the ratio of each component is in the present embodiment（In parts by mass）：
Artemisinin：0.1 part, ZPT：0.3 part, AESA：6.7 parts, CAB：9.0 parts, CDEA：3.2 parts, CMEA：1.5 parts, gather
Quaternary ammonium salt -10：1.0 parts, guar hydroxypropyltrimonium ammonium chloride：0.1 part, the D-pantothenyl aleohol solution of 50wt%：0.2 part, ammonium chloride
0.1 part, wherein Artemisinin includes qinghaosu and sweet wormwood wax；
Specifically preparation process is：
（1）Artemisinin is dissolved using double de- ethanol and double desacetoxy ethyl esters, and is formulated as the sweet wormwood liquid of 50wt%；
（2）Guar hydroxypropyltrimonium ammonium chloride is standby using the colloidal sol that deionized water is configured to 2wt% concentration；
（3）Poly-quaternary ammonium salt -10 using deionized water is configured to 5wt% colloidal sols standby；
（4）Dissolved during chelating agent EDTA-2Na is added into deionized water, obtained chelating agent solution；Chelating agent solution is heated up
CMEA is added after to 85 DEG C, 15min is stirred with the speed of 50r/min, obtain the mixed liquor of homogeneous transparent shape；
（5）By step（4）The mixed liquor for obtaining maintains 85 DEG C, and it is vacuumized, and is 0.08MPa to vacuum, thereafter
AESA and CAB-35 is added, insulation thereafter is 60 DEG C, adds 6510（CDEA）And standby poly-quaternary ammonium salt solution and standby molten
Glue, opens homogenizer, homogeneous 10min under keeping warm mode, then is incubated after 8 min and starts drop with the stir speed (S.S.) of 45r/min
Temperature；
（6）To step（5）When the mixed liquor for obtaining is cooled to 40 DEG C, the D-pantothenyl aleohol solution and ZPT of 50wt% are added, protected thereafter
Homogeneous 3min is carried out under temperature state, cooling is started thereafter；
（7）To step（6）When the mixed liquor for obtaining is cooled to 20 DEG C, ammonium chloride and standby sweet wormwood liquid are added, be well mixed
After stand 12h, that is, obtain the antibacterial type washing product.
The antibacterial type washing product of the present embodiment is emulsion liquid, its viscosity is tested at ambient temperature and is about
35600mPa.s；Using the method in QB/ T1974-2004 it is tested knowable to its：
Foam（40℃/mm）：More than 70
Working substance or solid content：More than 14.5；
The content of test to Artemisinin in the antibacterial type washing product of the present embodiment is 6 ‰ ~ 9 ‰ in addition, and it is pressed down
Bacterium measure of merit, it is known that its have it is obvious suppress MRSE, staphylococcus aureus, Escherichia coli, dermatophyte,
The bacteriums such as acrothesium floccosum or the effect of fungi, while also there is the influenza virus to being attached on hair obvious killing to imitate
Really.
Embodiment 2
Be the ratio of each component is in the present embodiment（In parts by mass）：
Sweet wormwood derivative：0.3 part, ZPT：0.8 part, AESA：7.7 parts, CAB：11.0 parts, CDEA：5.0 parts, CMEA：2.0 parts, gather
Quaternary ammonium salt -10：1.5 parts, guar hydroxypropyltrimonium ammonium chloride：0.5 part, the D-pantothenyl aleohol solution of 50wt%：0.4 part, ammonium chloride
0.3 part, Texapon Special：10.0 parts, hydroxyethyl cellulose：0.3 part, EGDS：2.0 parts, glycerine：4.0 parts, water-soluble silicon
Oil：0.5 part, wherein sweet wormwood derivative includes Artesunate, Artemether, arteether, dihydroartemisinine.
Specifically preparation process is：
（1）Dissolved during EDTA-2Na is added into deionized water, 90 DEG C of addition K12A are warmed up to thereafter（Texapon Special）,
CMEA, is completely dissolved to transparence with the speed stirring 15min of 65r/min with up to mixed solution；
（2）Poly-quaternary ammonium salt -10 is configured to 5wt% solution for standby using deionized water；By guar hydroxypropyltrimonium ammonium chloride
The colloidal sol for being configured to 2wt% concentration using deionized water is standby；Under the stir speed (S.S.) of 65r/min, by step（1）What is obtained is mixed
Close liquid to be vacuumized, be 0.08 ~ 0.1MPa to vacuum, AESA, CAB-35 are added thereafter, be incubated at 75 DEG C, add
6501st, EGDS, hydroxyethyl cellulose, standby poly-quaternary ammonium salt solution and standby colloidal sol, open thereafter homogenizer, homogeneous
15min；Lower the temperature after being incubated 10min again, stir speed (S.S.) is 50r/ min in temperature-fall period；
（3）To step（2）The D-pantothenyl aleohol solution of 50wt%, water-soluble silicon oil, sweet is added when the mixeding liquid temperature for obtaining is down to 50 DEG C
Oil and ZPT, lower the temperature after stirring homogeneous 5min；
（4）Dissolve Artemisinins using double de- ethanol and double desacetoxy ethyl esters, with and be configured to 40wt% concentration sweet wormwood liquid it is standby
With；Food grade colorant is configured to the solution for standby of 2wt% using deionized water；To step（3）The mixed liquor for obtaining is cooled to 40
DEG C when, lemon acid for adjusting pH is added under the stir speed (S.S.) of 40r/min, adds essence, Preservative Kathon CG(Methylchloroisothiazolinone/Methylisothiazolinone combination), standby pigment molten
Liquid, adds ammonium chloride and standby sweet wormwood liquid, stirs and make EGDS growing the grains completely, about 15 ~ 30min；
（5）Will be by step（4）The static 24h of mixed liquor for obtaining, that is, obtain the antibacterial type washing product.
The antibacterial type washing product of the present embodiment is emulsion liquid, viscosity is tested at normal temperatures and is about 40001mPa.s；
Using the method in QB/ T1974-2004 it is tested knowable to its：
Foam（40℃/mm）：More than 80
Working substance or solid content：More than 14.5
Active matter（In terms of K12A）：More than 10；
The content of test to sweet wormwood derivative in the antibacterial type washing product of the present embodiment is 8 ‰ ~ 10 ‰ in addition, and it is pressed down
Bacterium measure of merit, it is known that its have it is obvious suppress MRSE, staphylococcus aureus, Escherichia coli, dermatophyte,
The bacteriums such as acrothesium floccosum or the effect of fungi, while also there is the influenza virus to being attached on hair obvious killing to imitate
Really.
Embodiment 3
Be the ratio of each component is in the present embodiment（In parts by mass）：
Artemisinin and derivative：0.2 part, ZPT：0.6 part, AESA：7.5 parts, CAB：10.0 parts, CDEA：4.0 parts, CMEA：
2.0 parts, Polyquaternium-10：1.2 parts, guar hydroxypropyltrimonium ammonium chloride：0.3 part, the D-pantothenyl aleohol solution of 50wt%：0.3
Part, 0.2 part of ammonium chloride, Texapon Special：9.0 parts, hydroxyethyl cellulose：0.2 part, EGDS：1.5 parts, glycerine：3.0 parts, water
Dissolubility silicone oil：0.4 part；Wherein Artemisinin includes qinghaosu and sweet wormwood wax, and derivative includes Artesunate, Artemether and double
Hydrogen arteannuin；
Specifically preparation process is：
（1）Artemisinin and derivative are dissolved using double de- ethanol and double desacetoxy ethyl esters, and is formulated as the sweet wormwood of 30wt%
Liquid；
（2）Guar hydroxypropyltrimonium ammonium chloride is standby using the colloidal sol that deionized water is configured to 3wt% concentration；
（3）Poly-quaternary ammonium salt -10 using deionized water is configured to 4wt% colloidal sols standby；
（4）Dissolved during EDTA-2Na is added into deionized water, 85 DEG C of addition K12A are warmed up to thereafter（Texapon Special）,
CMEA, is completely dissolved to transparence with the speed stirring 15min of 60r/min with up to mixed solution；
（5）By step（4）The mixed liquor for obtaining maintains 85 DEG C, is vacuumized, and is 0.1MPa to vacuum, in 65r/min
Stir speed (S.S.) under, add AESA, CAB-35, be incubated thereafter at 60 ~ 80 DEG C, add 6501, EGDS, hydroxyethyl cellulose,
Standby poly-quaternary ammonium salt solution and standby colloidal sol, opens thereafter homogenizer, homogeneous 15min；Lower the temperature after being incubated 10 min again,
Stir speed (S.S.) is 50r/ min in temperature-fall period；
（6）To step（5）The mixeding liquid temperature for obtaining adds D-pantothenyl aleohol solution, the water-soluble silicon of 50wt% when being down to 40 ~ 60 DEG C
Oil, glycerine and ZPT, lower the temperature after stirring homogeneous 7min；
（7）Food grade colorant is configured to the solution for standby of 2wt% using deionized water；To step（6）The mixed liquor cooling for obtaining
During to 20 DEG C, lemon acid for adjusting pH is added under the stir speed (S.S.) of 40r/min, essence, Preservative Kathon CG(Methylchloroisothiazolinone/Methylisothiazolinone combination), standby pigment is added
Solution, adds ammonium chloride and standby sweet wormwood liquid, stirs and make EGDS growing the grains completely, about 15 ~ 30min；
（8）Will be by step（7）The static 24h of mixed liquor for obtaining, that is, obtain the antibacterial type washing product；
The antibacterial type washing product of the present embodiment is emulsion liquid, its viscosity is tested at ambient temperature and is about
40000mPa.s；Using the method in QB/ T1974-2004 it is tested knowable to its：
Foam（40℃/mm）：More than 75
Working substance or solid content：More than 13
Active matter（In terms of K12A）：More than 10；
The content tested in addition to Artemisinin and derivative in the antibacterial type washing product of the present embodiment is 7 ‰ ~ 10 ‰, right
It carries out fungistatic effect test, it is known that its have it is obvious suppress MRSE, staphylococcus aureus, Escherichia coli,
The bacteriums such as dermatophyte, acrothesium floccosum or the effect of fungi, while the influenza virus to being attached on hair also has substantially
Killing effect.
Claims (10)
1. a kind of antibacterial type washing product, it is characterised in that：The antibacterial type washing product includes following components：Artemisinin
And/or derivative, ZPT（ZPT）, AESA（AESA）, Cocoamidopropyl betaine
（CAB）, fatty acid distribution of coconut oil diglycollic amide（CDEA）, Coconut Fatty Acid Monoethanolamide（CMEA）, polyquaternium, guar gum hydroxypropyl
Trimethyl ammonium chloride, chelating agent, D-pantothenyl aleohol, ammonium chloride, solvent.
2. antibacterial type washing product according to claim 1, it is characterised in that：The antibacterial type washing product also include with
Lower component：Texapon Special.
3. antibacterial type washing product according to claim 1, it is characterised in that：The component of the antibacterial type washing product is also
Including：Pearling agent（EGDS）, glycerine, silicone oil.
4. antibacterial type washing product according to claim 1, it is characterised in that：The antibacterial type washing product also include with
Lower component：Hydroxyethyl cellulose.
5. antibacterial type washing product according to claim 1, it is characterised in that：The antibacterial type washing product also include with
Lower component：Citric acid.
6. antibacterial type washing product according to claim 1, it is characterised in that：Its in parts by mass, including following components：
Artemisinin and/or derivative：0.1 ~ 0.3 part, ZPT：0.3 ~ 0.8 part, AESA：6.7 ~ 7.7 parts, CAB：9.0 ~ 11.0 parts,
CDEA：3.2 ~ 5.0 parts, CMEA：1.5 ~ 2.0 parts, Polyquaternium-10：1.0 ~ 1.5 parts, guar hydroxypropyltrimonium ammonium chloride：
0.1 ~ 0.5 part, the D-pantothenyl aleohol solution of 50wt%：0.2 ~ 0.4 part, 0.1 ~ 0.3 part of ammonium chloride.
7. antibacterial type washing product according to claim 6, it is characterised in that：Its in parts by mass, also including with the following group
Point：Texapon Special：8.0 ~ 10.0 parts, hydroxyethyl cellulose：0.1 ~ 0.3 part, EGDS：1.3 ~ 2.0 parts, glycerine：1.0~
4.0 parts, water-soluble silicon oil：0.1 ~ 0.5 part.
8. a kind of preparation method of antibacterial type washing product, it is characterised in that：Comprise the following steps：
Artemisinin and/or derivative are dissolved using organic solvent, and is formulated as the sweet wormwood liquid of 30 ~ 50wt%；
Guar hydroxypropyltrimonium ammonium chloride is formulated as colloidal sol using deionized water；
Polyquaternium is formulated as polyquaternium solution using deionized water；
Dissolved during chelating agent is added into deionized water, obtained chelating agent solution；
CMEA is added after the chelating agent solution is heated up, the first mixed liquor is obtained；
First mixed liquor is vacuumized in a heated state, AESA and CAB is added thereafter, insulation thereafter is 60 ~ 80
DEG C, CDEA, the polyquaternium solution and the colloidal sol are added, homogenization is carried out under keeping warm mode, obtain the second mixing
Liquid；
40 ~ 60 DEG C are cooled to second mixed liquor, the D-pantothenyl aleohol solution and ZPT of 50wt% are added, thereafter under keeping warm mode
Homogenization is carried out, the 3rd mixed liquor is obtained；
3rd mixed liquor is cooled to 20 ~ 40 DEG C, ammonium chloride and the sweet wormwood liquid is added, stood thereafter, obtain the suppression
Bacterial type washing product.
9. a kind of preparation method of antibacterial type washing product, it is characterised in that：Comprise the following steps：
Artemisinin and/or derivative are dissolved using organic solvent, and is formulated as the sweet wormwood liquid of 30 ~ 50wt%；
Guar hydroxypropyltrimonium ammonium chloride is formulated as colloidal sol using deionized water；
Polyquaternium is formulated as polyquaternium solution using deionized water；
Food grade colorant is formulated as pigment solution using deionized water；
Dissolved during EDTA ~ 2Na is added into deionized water, obtained chelating agent solution；
After the chelating agent solution is warming up into 85 ~ 90 DEG C, Texapon Special and CMEA are added, obtain the first mixed liquor；
First mixed liquor is vacuumized at 85 ~ 90 DEG C, AESA and CAB is added under stirring thereafter, thereafter
It is 60 ~ 80 DEG C to be incubated, and adds CDEA, EGDS, hydroxyethyl cellulose, the polyquaternium solution and the colloidal sol, in insulation shape
Homogenization is carried out under state, the second mixed liquor is obtained；
40 ~ 60 DEG C are cooled to second mixed liquor, D-pantothenyl aleohol solution, water-soluble silicon oil, glycerine and the ZPT of 50wt% is added,
Thereafter homogenization is carried out under keeping warm mode, the 3rd mixed liquor is obtained；
3rd mixed liquor is cooled to 20 ~ 40 DEG C, the pigment solution is added, sweet wormwood liquid, ammonium chloride and lemon is added
Acid, stands afterwards completely to EGDS growing the grains, obtains the antibacterial type washing product.
10. the preparation method of a kind of antibacterial type washing product according to claim 8 ~ 9, it is characterised in that：It is described organic
Solvent is the mixture of double de- ethanol and double desacetoxy ethyl esters.
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| CN113476347A (en) * | 2021-07-08 | 2021-10-08 | 河南天源海汇药物研究有限公司 | Sweet wormwood bath lotion formula and preparation method |
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| CN105326689A (en) * | 2015-11-09 | 2016-02-17 | 秦瑜 | Preparing method for traditional Chinese medicine dandruff-removing shampoo |
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