CN106721847A - Regulating menstruation is uncomfortable to be alleviated dysmenorrhoea and solves cold beverage in palace and preparation method thereof - Google Patents
Regulating menstruation is uncomfortable to be alleviated dysmenorrhoea and solves cold beverage in palace and preparation method thereof Download PDFInfo
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- CN106721847A CN106721847A CN201611166676.3A CN201611166676A CN106721847A CN 106721847 A CN106721847 A CN 106721847A CN 201611166676 A CN201611166676 A CN 201611166676A CN 106721847 A CN106721847 A CN 106721847A
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- 206010013935 Dysmenorrhoea Diseases 0.000 title claims abstract description 37
- 230000005906 menstruation Effects 0.000 title claims abstract description 25
- 230000001105 regulatory effect Effects 0.000 title claims abstract description 24
- 235000020965 cold beverage Nutrition 0.000 title claims abstract description 17
- 238000002360 preparation method Methods 0.000 title claims description 19
- 239000000843 powder Substances 0.000 claims abstract description 44
- 235000013361 beverage Nutrition 0.000 claims abstract description 30
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims abstract description 24
- 239000002994 raw material Substances 0.000 claims abstract description 21
- 235000000346 sugar Nutrition 0.000 claims abstract description 21
- 238000000605 extraction Methods 0.000 claims abstract description 18
- 239000003814 drug Substances 0.000 claims abstract description 14
- 244000241838 Lycium barbarum Species 0.000 claims abstract description 13
- 235000015459 Lycium barbarum Nutrition 0.000 claims abstract description 13
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- 244000025254 Cannabis sativa Species 0.000 claims abstract description 9
- 235000000604 Chrysanthemum parthenium Nutrition 0.000 claims abstract description 9
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- 235000000802 Leonurus cardiaca ssp. villosus Nutrition 0.000 claims abstract description 9
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- 235000021552 granulated sugar Nutrition 0.000 claims abstract description 8
- 238000012545 processing Methods 0.000 claims abstract description 8
- 235000012950 rattan cane Nutrition 0.000 claims abstract description 8
- 102000004169 proteins and genes Human genes 0.000 claims abstract description 5
- 108090000623 proteins and genes Proteins 0.000 claims abstract description 5
- 229920001503 Glucan Polymers 0.000 claims description 23
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 claims description 22
- 150000003839 salts Chemical class 0.000 claims description 18
- 239000012071 phase Substances 0.000 claims description 17
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 17
- 238000000502 dialysis Methods 0.000 claims description 13
- 238000002386 leaching Methods 0.000 claims description 13
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- 235000014655 lactic acid Nutrition 0.000 claims description 11
- 239000000080 wetting agent Substances 0.000 claims description 10
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- 238000002156 mixing Methods 0.000 claims description 9
- 241000207925 Leonurus Species 0.000 claims description 7
- CSNNHWWHGAXBCP-UHFFFAOYSA-L Magnesium sulfate Chemical compound [Mg+2].[O-][S+2]([O-])([O-])[O-] CSNNHWWHGAXBCP-UHFFFAOYSA-L 0.000 claims description 6
- PMZURENOXWZQFD-UHFFFAOYSA-L Sodium Sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 claims description 6
- 239000008346 aqueous phase Substances 0.000 claims description 6
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- BFNBIHQBYMNNAN-UHFFFAOYSA-N ammonium sulfate Chemical compound N.N.OS(O)(=O)=O BFNBIHQBYMNNAN-UHFFFAOYSA-N 0.000 claims description 3
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Classifications
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Preparation or treatment thereof
- A23L2/385—Concentrates of non-alcoholic beverages
- A23L2/39—Dry compositions
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Preparation or treatment thereof
- A23L2/52—Adding ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/11—Pteridophyta or Filicophyta (ferns)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K36/27—Asclepiadaceae (Milkweed family), e.g. hoya
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
-
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/533—Leonurus (motherwort)
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/716—Clematis (leather flower)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/78—Saururaceae (Lizard's-tail family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
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- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
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- Mycology (AREA)
- Alternative & Traditional Medicine (AREA)
- Microbiology (AREA)
- Botany (AREA)
- Nutrition Science (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Non-Alcoholic Beverages (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The present invention relates to the cold beverage of a kind of uncomfortable alleviation dysmenorrhoea of regulating menstruation and solution palace, beverage is formed by the Raw material processing of following weight portion：10 15 parts of wolfberry fruit extract dry powder, 20 40 parts of Chinese medical extract dry powder, 58 parts of brown sugar powder, the Chinese medical extract is dried through extraction by the raw material of following weight portion and obtained：10 15 parts of wild Radix Angelicae Sinensis, 12 18 parts of motherwort, 10 15 parts of DUIYUECAO, 10 15 parts of giantreed, 18 25 parts of white granulated sugar, 35 45 parts of protein sugar, 25 35 parts of citric acid, 8 12 parts of Curculigo rhynchophyllum, 8 12 parts of Jinsha rattan, 10 15 parts of the root of Chinese clematis, 10 15 parts of Rhizoma Rohdeae Japonicae, 8 12 parts of the tuber of dwarf lilyturf, 5 10 parts of folium artemisiae argyi, 8 15 parts of dredging grass.Beverage taste of the invention and in good taste, the bitter taste without obvious Chinese medicine, free from extraneous odour, it is easy to received；Rationally, replenishing and activating blood, menstruction regulating and pain relieving, the function that tonifies the liver and kidney significantly, can effectively mitigate hypogastralgia, falling inflation, pain in low back and legs, headache and menstrual period entanglement, the menstrual period of youth acne uncomfortable symptom to each material combination in Chinese medical extract；Can effectively solve in addition palace tremble with fear cause be difficult pregnancy.
Description
Technical field
The present invention relates to a kind of Gynecological health beverage, dysmenorrhoea and solution are alleviated more particularly to a kind of regulating menstruation is uncomfortable
Cold beverage in palace and preparation method thereof.
Background technology
Dysmenorrhoea refers to that women is expert at through the front and rear or menstrual period and hypogastralgia, falling inflation occurs, with the soreness of waist or other uncomfortable, degree
It is heavier so that influence live and work, often sent out with the menstrual cycle, severe patient can with n and V, dripping cold sweat, cold limbs,
Even faint, influence is brought to work and life.
Clinical at present to be often classified as primary dysmenorrhea and the class of acquired dysmenorrhea two, the primary dysmenorrhea cause of disease is not yet complete at present
Complete to understand, do not have any organic disease, dysmenorrhoea is most commonly in less than the 25 years old unmarried women not produced, mostly 6 ~ 12 after first menses
Month morbidity, greatly more to reproduction age, can alleviate after marriage, or even symptom disappear.Acquired dysmenorrhea has the clear and definite cause of disease, is common in reproduction age woman
Married woman behind female, particularly 30 years old, its reproductive organs there occurs organic disease, gynecologial examination can find uterus increase,
Limitation of activity, there is tenderness, annex increases thick or sheet and thickens, has tenderness；Its dysmenorrhoea is common to have irritated, sad irritability uncomfortable in chest, the heart to shy
Insomnia, headache and dizzy, n and V, stomachache diarrhoea, lassitude hypodynamia, pale complexion, ice-cold four limbs, dripping cold sweat, collapse are fainted
Etc. symptom, symptom must could be eliminated by the good protopathy of symptomatic treatment, shown according to relevant investigation, the morbidity in China women
Rate is 33.15%, and feature person accounts for 53.2% in base.
The traditional Chinese medical science thinks, dysmenorrhoea is menses not smooth, caused by energy stagnation and blood stasis, and " not general rule bitterly " is the most basic viewpoint of the traditional Chinese medical science, warp
Water goes out all kidneys, means that menopathy and renal function have direct relation, also related to spleen, liver, qi and blood, chong channel, conception vessel, uterus, pain
Through being mainly kidney qi virtual loss, insufficiency of vital energy and blood, the pressure of each side is added, make stagnation of liver qi, so that QI-blood circulation has some setbacks, cause pain
Through, therefore, menstruation regulating treats big method based on kidney tonifying, invigorating the spleen, soothing the liver, recuperating qi-blood.
For the treatment of dysmenorrhoea, doctor trained in Western medicine emphasizes mostly analgesic, spasmolysis, anti-inflammatory, hormone and symptomatic treatment etc., although it is fast to take effect
Victory, side effect is big, and curative effect is difficult to persistently, and the traditional Chinese medical science then foundation organic conception, diagnosis and treatment based on an overall analysis of the illness and the patient's condition, though analgesic speed is not as good as Western medicine,
But through one section of systematic treating, it is expected to fully recover, can more be adjusted by daily dietotherapy and reach the effect for mitigating dysmenorrhoea symptom.
Gong Han, refers to women's insufficiency of the kidney yang, and uterus is lost in warm occurred lower abdomen falling inflation, and pain obtains hot, relaxes, in vain
Many, the dysmenorrhoea of band, menstrual disorder, deep tense pulse, many Tianjin of thin white fur of tongue are main symptom.It is name of disease under theory of traditional Chinese medical science that palace is trembled with fear, no
Can be covered with the specific name of disease of doctor trained in Western medicine, but clinical some the common gynaecology's active chronic inflammations of doctor trained in Western medicine are (such as：Vaginitis, uterine neck
Inflammation, endometritis, adnexitis, etc.) the cold Coryza Treated by Syndrome Differentiation in palace can be used.
Traditional Chinese medicine thinks that palace is trembled with fear and kidney deficiency, and Spleen-Qi Deficiency, the deficiency of blood, liver depression, phlegm wet is damp and hot, and the reason such as blood stasis is relevant.And doctor trained in Western medicine
Think more than such some symptoms and age factor, trophic factor, mental element, endocrine factors (hypothalamus, thyroid gland, kidney
Upper gland, the moon razes gland), developmental factors, inflammation, tumour waits relevant.The cold desired pregnancy in palace should start with terms of two, and first, put down
Element note can not the cold Frozen of eating cold and uncooked food excessively, note seasonal variations, it is warming；Second can take Chinese medicine warm yang transforming qi, consolidate and add essence, adjust
Reason punching is appointed.Gynaecology's conditioning Chinese medicine composition present in prior art, its unitary function, the conditioning effect especially trembled with fear to palace
It is not good.
The content of the invention
It is an object of the invention to solve the deficiencies in the prior art, there is provided a kind of regulating menstruation is uncomfortable to alleviate dysmenorrhoea and solution
The cold beverage in palace.
It is another object of the present invention to provide a kind of uncomfortable system alleviated dysmenorrhoea and solve the cold beverage in palace of regulating menstruation
Preparation Method.
The technical solution adopted for the present invention to solve the technical problems is：
Regulating menstruation is uncomfortable to be alleviated dysmenorrhoea and solves the cold beverage in palace, and the beverage is formed by the Raw material processing of following weight portion：
10-15 parts of wolfberry fruit extract dry powder, 20-40 parts of Chinese medical extract dry powder, 5-8 parts of brown sugar powder, the Chinese medical extract is by following
The raw material of weight portion is dried through extraction and obtained：Wild Radix Angelicae Sinensis 10-15 parts, motherwort 12-18 parts, DUIYUECAO 10-15 parts, giantreed 10-
15 parts, white granulated sugar 18-25 parts, protein sugar 35-45 parts, citric acid 25-35 parts, Curculigo rhynchophyllum 8-12 parts, 8-12 parts of Jinsha rattan,
Root of Chinese clematis 10-15 parts, Rhizoma Rohdeae Japonicae 10-15 parts, tuber of dwarf lilyturf 8-12 parts, folium artemisiae argyi 5-10 parts, dredge 8-15 parts of grass.
Wild Radix Angelicae Sinensis：Enrich blood；Promoting blood circulation；Menstruction regulating and pain relieving；Moisturize laxation, the main all cards of the deficiency of blood；Irregular menstruation；Amenorrhea；Dysmenorrhoea；Abdominal mass
Knot is poly-；Uterine bleeding；Asthenia cold abdominalgia；Impotence numbness；Numbness；Intestines are dry and shit is difficult；Weight after dysentery characterized by blood in the stool；Ulcer sores；Injury from falling down.
Motherwort：Invigorate blood circulation, silt of dispelling, menstruation regulating, disappear water, treats menoxenia, threatened abortion difficult labour, placenta retension, postpartum blood
Dizzy, abdominal pain due to blood stasis, metrorrhagia and metrostaxis, rushes down blood at hematuria, carbuncle swells sore.
Giantreed：Gone mad for pyreticosis, consumptive disease hectic fever due to yin, stranguria, urine leaching pain is unfavorable, acute toothache.
Curculigo rhynchophyllum：Moistening lung for removing phlegm, relieving cough and asthma, calm invigorating the spleen, invigorates the kidney and stops nocturnal emission, for dyspnea and cough due to deficiency of the kidney, soreness of waist and knee joint, in vain
Band, seminal emission.
Jinsha rattan：Control urinary tract infections, lithangiuria, gonorrhoea under band, difficult urination, nephritic dropsy, jaundice with damp-heat pathogen, flu hair
Heat, cough, abscess of throat, enteritis, dysentery are scalded, erysipelas.
The root of Chinese clematis：Can wind-damp dispelling, diuresis, stimulate the menstrual flow, ease pain, control damp and hot chill, migraines, jaundice edema, fish-bone fishbone larynx, waist
Knee legs and feet crymodynia.
The tuber of dwarf lilyturf：There is nourishing Yin and moistening lung the tuber of dwarf lilyturf.Often the edible tuber of dwarf lilyturf, your taste can be nursed one's health
Folium artemisiae argyi：For spitting blood, bleeding from five sense organs or subcutaneous tissue, uterine bleeding, menorrhalgia, blood under threatened abortion, few abdomen crymodynia, through uncomfortable, uterus cold infertile of trembling with fear；Control outward
Pruitus.Vinegar Chinese mugwort charcoal warming channel for arresting bleeding, for deficient cold type bleeding.
Rationally, replenishing and activating blood, menstruction regulating and pain relieving, the function that tonifies the liver and kidney show each material combination in Chinese medical extract of the invention
Write, can effectively mitigate hypogastralgia, falling inflation, pain in low back and legs, headache and menstrual period entanglement, the menstrual period of youth acne uncomfortable symptom；
Can effectively solve in addition palace tremble with fear cause be difficult pregnancy.
Preferably, the beverage is formed by the Raw material processing of following weight portion：12 parts of wolfberry fruit extract dry powder, traditional Chinese medicine extraction
30 parts of thing dry powder, 6 parts of brown sugar powder, the Chinese medical extract is dried through extraction by the raw material of following weight portion and obtained：Wild Radix Angelicae Sinensis 12
Part, 15 parts of motherwort, 12 parts of DUIYUECAO, 12 parts of giantreed, 20 parts of white granulated sugar, 40 parts of protein sugar, 30 parts of citric acid, Curculigo rhynchophyllum
10 parts, 9 parts of Jinsha rattan, 12 parts of the root of Chinese clematis, 12 parts of Rhizoma Rohdeae Japonicae, 10 parts of the tuber of dwarf lilyturf, 8 parts of folium artemisiae argyi, 12 parts of dredging grass
A kind of uncomfortable preparation method alleviated dysmenorrhoea and solve the cold beverage in palace of regulating menstruation, the preparation method step is as follows：
The first step：The preparation of Chinese medical extract；
(1) extract：The raw material of formula ratio adds the ethanol water of 6-8 times of volume fraction 70-75%, in 60-70 DEG C of backflow
Extract 3-4 hours, be subsequently cooled to room temperature filtering, obtain a leaching liquor；
(2) aqueous two-phase extraction：To step（1）Leaching liquor in, add appropriate modified glucan and inorganic salts, after concussion mixing,
10-20 minutes is stood, phase in collection, the modified glucan is lactic acid oligomer modified glucan；
(3) dialysis concentration：Will be saturating in retention relative molecular mass is for the dialysis membrane of 3000-5000Da on step (2) gained
Analysis obtains dialyzate after 3-5 hours, dialyzate is freeze-dried to obtain Chinese medical extract dry powder；
Second step：Prepare beverage；
The wolfberry fruit extract dry powder of formula ratio, Chinese medical extract dry powder and brown sugar powder are well mixed, appropriate wetting agent profit is added
It is wet, then obtain particulate beverage finished product through granulating and drying.
Two phase aqueous extraction system is made up of immiscible modified glucan and inorganic salts, is had using the core in leaching liquor
Selectivity distribution of the effect composition in modified glucan and inorganic salts, makes it be separated with other impurities in leaching liquor, so as to reach
The purpose for isolating and purifying.In present inventor's experimentation find use lactic acid oligomer modified glucan, increase with it is inorganic
The polarity of salt is poor, so as to accelerate split-phase speed, without centrifugation can success split-phase, reduce operation difficulty, increased purifying effect
Rate；
Preferably, inorganic salts described in first step step (2) are any one in ammonium sulfate, sodium sulphate or magnesium sulfate.
Preferably, the lactic acid oligomer modified glucan addition is the 4-6% of double-aqueous phase system gross mass, inorganic salts matter
It is the 1-2% of double-aqueous phase system gross mass to measure.
Preferably, wetting agent is the ethanol water or pure water of volume fraction 8-12% in second step.
The beneficial effects of the invention are as follows：Beverage products purity of the invention is high, and boiling water is taken after mixing it with water conveniently, and impurity content is low, is inhaled
Receive utilization rate high, and taste and in good taste, the bitter taste without obvious Chinese medicine, free from extraneous odour, it is easy to received；In Chinese medical extract
Rationally, replenishing and activating blood, menstruction regulating and pain relieving, the function that tonifies the liver and kidney significantly, can effectively mitigate hypogastralgia, falling inflation, waist to each material combination
Sour skelagia, headache and menstrual period entanglement, the menstrual period of youth acne uncomfortable symptom；Can effectively solve in addition palace tremble with fear cause be difficult bosom
It is pregnant.
Specific embodiment
Below by specific embodiment, technical scheme is described in further detail.
Embodiment 1：
Regulating menstruation is uncomfortable to be alleviated dysmenorrhoea and solves the cold beverage in palace, and the beverage is formed by the Raw material processing of following weight portion：
10 parts of wolfberry fruit extract dry powder, 20 parts of Chinese medical extract dry powder, 5 parts of brown sugar powder, the Chinese medical extract is by following weight portion
Raw material is dried through extraction and obtained：10 parts of wild Radix Angelicae Sinensis, 12 parts of motherwort, 10 parts of DUIYUECAO, 10 parts of giantreed, 18 parts of white granulated sugar, albumen
35 parts of sugar, 25 parts of citric acid, 8 parts of Curculigo rhynchophyllum, 8 parts of Jinsha rattan, 10 parts of the root of Chinese clematis, 10 parts of Rhizoma Rohdeae Japonicae, 8 parts of the tuber of dwarf lilyturf, folium artemisiae argyi 5
Part, 8 parts of dredging grass, the preparation method step of the beverage is as follows：
The first step：The preparation of Chinese medical extract；
(1) extract：The raw material of formula ratio adds the ethanol water of 6 times of volume fraction 70%, small in 60 DEG C of refluxing extractions 4
When, room temperature filtering is subsequently cooled to, obtain a leaching liquor；
(2) aqueous two-phase extraction：To step（1）Leaching liquor in, add appropriate modified glucan and inorganic salts, after concussion mixing,
10 minutes are stood, phase in collection, the modified glucan is lactic acid oligomer modified glucan；
(3) dialysis concentration：By dialysis 5 is small in retention relative molecular mass is for the dialysis membrane of 3000Da on step (2) gained
When after dialyzate, dialyzate it is freeze-dried obtain Chinese medical extract dry powder；
Second step：Prepare beverage；
The wolfberry fruit extract dry powder of formula ratio, Chinese medical extract dry powder and brown sugar powder are well mixed, appropriate wetting agent profit is added
It is wet, then obtain particulate beverage finished product through granulating and drying.
Inorganic salts described in first step step (2) are ammonium sulfate, and the lactic acid oligomer modified glucan addition is double water
The 4% of phase system gross mass, inorganic salts quality is the 1% of double-aqueous phase system gross mass, and wetting agent is volume fraction 8% in second step
Ethanol water.
Embodiment 2：
Regulating menstruation is uncomfortable to be alleviated dysmenorrhoea and solves the cold beverage in palace, and the beverage is formed by the Raw material processing of following weight portion：
15 parts of wolfberry fruit extract dry powder, 40 parts of Chinese medical extract dry powder, 8 parts of brown sugar powder, the Chinese medical extract is by following weight portion
Raw material is dried through extraction and obtained：15 parts of wild Radix Angelicae Sinensis, 18 parts of motherwort, 15 parts of DUIYUECAO, 15 parts of giantreed, 25 parts of white granulated sugar, albumen
45 parts of sugar, 35 parts of citric acid, 12 parts of Curculigo rhynchophyllum, 12 parts of Jinsha rattan, 15 parts of the root of Chinese clematis, 15 parts of Rhizoma Rohdeae Japonicae, 12 parts of the tuber of dwarf lilyturf, Chinese mugwort
10 parts of leaf, 15 parts of dredging grass, the preparation method step of the beverage is as follows：
The first step：The preparation of Chinese medical extract；
(1) extract：The raw material of formula ratio adds the ethanol water of 8 times of volume fraction 5%, in 70 DEG C of refluxing extractions 3 hours,
Room temperature filtering is subsequently cooled to, a leaching liquor is obtained；
(2) aqueous two-phase extraction：To step（1）Leaching liquor in, add appropriate modified glucan and inorganic salts, after concussion mixing,
10 minutes are stood, phase in collection, the modified glucan is lactic acid oligomer modified glucan；
(3) dialysis concentration：By dialysis 3 is small in retention relative molecular mass is for the dialysis membrane of 5000Da on step (2) gained
When after dialyzate, dialyzate it is freeze-dried obtain Chinese medical extract dry powder；
Second step：Prepare beverage；
The wolfberry fruit extract dry powder of formula ratio, Chinese medical extract dry powder and brown sugar powder are well mixed, appropriate wetting agent profit is added
It is wet, then obtain particulate beverage finished product through granulating and drying.
Inorganic salts described in first step step (2) are sodium sulphate.The lactic acid oligomer modified glucan addition is double water
The 6% of phase system gross mass, inorganic salts quality is the 2% of double-aqueous phase system gross mass, and wetting agent is volume fraction 12% in second step
Ethanol water.
Embodiment 3：
Regulating menstruation is uncomfortable to be alleviated dysmenorrhoea and solves the cold beverage in palace, and the beverage is formed by the Raw material processing of following weight portion：
12 parts of wolfberry fruit extract dry powder, 30 parts of Chinese medical extract dry powder, 6 parts of brown sugar powder, the Chinese medical extract is by following weight portion
Raw material is dried through extraction and obtained：12 parts of wild Radix Angelicae Sinensis, 15 parts of motherwort, 12 parts of DUIYUECAO, 12 parts of giantreed, 20 parts of white granulated sugar, albumen
40 parts of sugar, 30 parts of citric acid, 10 parts of Curculigo rhynchophyllum, 9 parts of Jinsha rattan, 12 parts of the root of Chinese clematis, 12 parts of Rhizoma Rohdeae Japonicae, 10 parts of the tuber of dwarf lilyturf, Chinese mugwort
8 parts of leaf, 12 parts of dredging grass, the preparation method step of the beverage is as follows：
The first step：The preparation of Chinese medical extract；
(1) extract：The raw material of formula ratio adds the ethanol water of 7 times of volume fraction 70%, small in 65 DEG C of refluxing extractions 3
When, room temperature filtering is subsequently cooled to, obtain a leaching liquor；
(2) aqueous two-phase extraction：To step（1）Leaching liquor in, add appropriate modified glucan and inorganic salts, after concussion mixing,
15 minutes are stood, phase in collection, the modified glucan is lactic acid oligomer modified glucan；
(3) dialysis concentration：By dialysis 4 is small in retention relative molecular mass is for the dialysis membrane of 4000Da on step (2) gained
When after dialyzate, dialyzate it is freeze-dried obtain Chinese medical extract dry powder；
Second step：Prepare beverage；
The wolfberry fruit extract dry powder of formula ratio, Chinese medical extract dry powder and brown sugar powder are well mixed, appropriate wetting agent profit is added
It is wet, then obtain particulate beverage finished product through granulating and drying.
Inorganic salts described in first step step (2) are magnesium sulfate.The lactic acid oligomer modified glucan addition is double water
The 5% of phase system gross mass, inorganic salts quality is the 1.5% of double-aqueous phase system gross mass, and wetting agent is pure water in second step.
The beverage granules that embodiment 1-3 is prepared are used for clinical trial, Subject Population and its basic document：Select on the spot
The 300 women's voluntary participation experiments of Hunan Phoenix County.In 300 people, minimum 25 years old of age, the maximum 35 years old.This 300 experiments
Dysmenorrhoea and palace sympotoms caused by cold factors shape are obvious in person, are randomly divided into 3 groups, and every group of 100 people take the beverage that embodiment 1-3 is prepared respectively
Electuary.
The clinical symptoms of Subject Population：Menstruation is delayed, and one week after, at most two weeks, how premenstrual underbelly falling inflation, the moon are moved back at least
Black dull through color, leucorrhea increasing, fishy smell weight, waist urushic acid is cold, and four limbs are not warm, and underbelly is sent out cool, and few patients' dysmenorrhoea reaches and is difficult to bear
The degree received.
Take mode：Menstrual period start boiling water and take after mixing it with water, each 2.5g, and the daily morning and evening is each once, and menstrual period terminate to stop, and take altogether
With three menstrual period.
Effect assessment：Recovery from illness, dysmenorrhoea and palace sympotoms caused by cold factors shape disappear；Effectively, dysmenorrhoea and palace sympotoms caused by cold factors shape are significantly alleviated, invalid, pain
Through with palace sympotoms caused by cold factors shape without alleviation.
The beverage granules that embodiment 1-3 is prepared are used for clinical trial results such as following table：
In sum, Chinese medicine composition beverage regulating menstruation of the invention is uncomfortable, alleviates dysmenorrhoea and solves the cold effect is significant in palace, tool
There are prominent substantive distinguishing features and significant progress.
Model case
Case 1：Patient Wang, 28 years old, is married 1 year half, always unpregnancy, and menstruation is delayed, and averagely pushes away one week after, premenstrual underbelly pendant
Swollen, menstruation color is black dull, leucorrhea increasing, and fishy smell weight, waist urushic acid is cold, and underbelly is sent out cool, and in December, 2015 is through doctor's clinical diagnosis
Palace tremble with fear cause it is infertile, 1 menstrual period in 2016 starts boiling water and takes after mixing it with water the beverage of embodiment 3, and each 2.5g is daily sooner or later each
Once, menstrual period terminate stop, three menstrual period are taken altogether.In April, 2016 doctor's clinical diagnosis, palace sympotoms caused by cold factors shape disappears, dysmenorrhoea
Significantly improve, in August, 2016, Pregnant symptom occurs in Wang, September is clinical to confirm pregnancy.
Case 2：Patient Chen, 38 years old, is married 15 years half, and menstruation is delayed, and premenstrual underbelly falling inflation, menstruation color is black dull, in vain
Band is more, and fishy smell weight, waist urushic acid is cold, and underbelly is sent out cool, is the cold dysmenorrhoea in palace through doctor's clinical diagnosis, and patient's readme in August, 2015 is standby
Pregnant two tire, the unpregnancy always to 2016 3,4 menstrual periods in 2016 start boiling water and take after mixing it with water the beverage of embodiment 3, each 2.5g, daily
Morning and evening is each once, and menstrual period terminate to stop, and three menstrual period are taken altogether.In July, 2016 doctor's clinical diagnosis, palace sympotoms caused by cold factors shape disappears,
Dysmenorrhoea is also significantly improved, and Pregnant symptom occurs in November, 2016, Chen, clinical at the beginning of 12 months to confirm pregnancy.
Embodiment described above is a kind of preferably scheme of the invention, not makees any formal to the present invention
Limitation, also has other variants and remodeling on the premise of without departing from the technical scheme described in claim.
Claims (6)
1. regulating menstruation is uncomfortable alleviates dysmenorrhoea and solves the cold beverage in palace, it is characterised in that：The beverage is by following weight portion
Raw material processing is formed：10-15 parts of wolfberry fruit extract dry powder, 20-40 parts of Chinese medical extract dry powder, 5-8 parts of brown sugar powder, the Chinese medicine
Extract is dried through extraction by the raw material of following weight portion and obtained：Wild Radix Angelicae Sinensis 10-15 parts, motherwort 12-18 parts, DUIYUECAO 10-
15 parts, giantreed 10-15 parts, white granulated sugar 18-25 parts, protein sugar 35-45 parts, citric acid 25-35 parts, Curculigo rhynchophyllum 8-12 parts, gold
Sha Teng 8-12 parts, root of Chinese clematis 10-15 parts, Rhizoma Rohdeae Japonicae 10-15 parts, tuber of dwarf lilyturf 8-12 parts, folium artemisiae argyi 5-10 parts, dredge 8-15 parts of grass.
2. regulating menstruation according to claim 1 is uncomfortable alleviates dysmenorrhoea and solves the cold beverage in palace, it is characterised in that：It is described
Beverage is formed by the Raw material processing of following weight portion：12 parts of wolfberry fruit extract dry powder, 30 parts of Chinese medical extract dry powder, brown sugar powder 6
Part, the Chinese medical extract is dried through extraction by the raw material of following weight portion and obtained：12 parts of wild Radix Angelicae Sinensis, 15 parts of motherwort, to the moon
12 parts of grass, 12 parts of giantreed, 20 parts of white granulated sugar, 40 parts of protein sugar, 30 parts of citric acid, 10 parts of Curculigo rhynchophyllum, 9 parts of Jinsha rattan, prestige
12 parts of medicine xiaolingxian, 12 parts of Rhizoma Rohdeae Japonicae, 10 parts of the tuber of dwarf lilyturf, 8 parts of folium artemisiae argyi, 12 parts of dredging grass.
3. the uncomfortable preparation method alleviated dysmenorrhoea and solve the cold beverage in palace of regulating menstruation described in a kind of claim 1 or 2, its
It is characterised by：The preparation method step is as follows：
The first step：The preparation of Chinese medical extract；
(1) extract：The raw material of formula ratio adds the ethanol water of 6-8 times of volume fraction 70-75%, in 60-70 DEG C of backflow
Extract 3-4 hours, be subsequently cooled to room temperature filtering, obtain a leaching liquor；
(2) aqueous two-phase extraction：To step（1）Leaching liquor in, add appropriate modified glucan and inorganic salts, after concussion mixing,
10-20 minutes is stood, phase in collection, the modified glucan is lactic acid oligomer modified glucan；
(3) dialysis concentration：Will be saturating in retention relative molecular mass is for the dialysis membrane of 3000-5000Da on step (2) gained
Analysis obtains dialyzate after 3-5 hours, dialyzate is freeze-dried to obtain Chinese medical extract dry powder；
Second step：Prepare beverage；
The wolfberry fruit extract dry powder of formula ratio, Chinese medical extract dry powder and brown sugar powder are well mixed, appropriate wetting agent profit is added
It is wet, then obtain particulate beverage finished product through granulating and drying.
4. the uncomfortable preparation method alleviated dysmenorrhoea and solve the cold beverage in palace of regulating menstruation according to claim 3, it is special
Levy and be：Inorganic salts described in first step step (2) are ammonium sulfate, sodium sulphate or magnesium sulfate.
5. the uncomfortable preparation method alleviated dysmenorrhoea and solve the cold beverage in palace of regulating menstruation according to claim 3, it is special
Levy and be, the lactic acid oligomer modified glucan addition is the 4-6% of double-aqueous phase system gross mass, inorganic salts quality is double water
The 1-2% of phase system gross mass.
6. the uncomfortable preparation method alleviated dysmenorrhoea and solve the cold beverage in palace of regulating menstruation according to claim 3, it is special
Levy and be, wetting agent is the ethanol water or pure water of volume fraction 8-12% in second step.
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Cited By (1)
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| CN107410485A (en) * | 2017-06-19 | 2017-12-01 | 宁国市仙之居家庭农场 | A kind of yogurt production method based on the peaceful root of purple-flowered peucedanum |
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| CN103223152A (en) * | 2013-03-23 | 2013-07-31 | 王秀荣 | Medicine for treating infertility caused by uterus coldness |
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| CN101780262A (en) * | 2009-10-28 | 2010-07-21 | 吴清玲 | Traditional Chinese medicine plaster for treating dysmenorrhea |
| CN102125285A (en) * | 2010-12-30 | 2011-07-20 | 陈慧婷 | Formula of cortex moutan radicis/herba leonuri beverage for relieving dysmenorrheal and preparation method thereof |
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