CN106692475A - Traditional Chinese medicine composition for treating alopecia as well as preparation method thereof - Google Patents
Traditional Chinese medicine composition for treating alopecia as well as preparation method thereof Download PDFInfo
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K36/13—Coniferophyta (gymnosperms)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/236—Ligusticum (licorice-root)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
- A61K36/605—Morus (mulberry)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
- A61K36/638—Ligustrum, e.g. Chinese privet
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/704—Polygonum, e.g. knotweed
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/80—Scrophulariaceae (Figwort family)
- A61K36/804—Rehmannia
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
- A61K36/815—Lycium (desert-thorn)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
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Abstract
The invention discloses a traditional Chinese medicine composition for treating alopecia as well as a preparation method thereof. The Chinese patent medicine for treating the alopecia is mainly prepared from the following traditional Chinese medicine materials in parts by mass: 50 to 80 parts of Chinese angelica, 30 to 60 parts of radix rehmanniae, 15 to 45 parts of rhizoma chuanxiong, 30 to 60 parts of mulberries, 50 to 80 parts of radix astragali seu hedysari, 60 to 100 parts of black sesame, 15 to 45 parts of folium mori, 60 to 100 parts of prepared tuber of multiflower knotweed, 50 to 80 parts of the fruit of Chinese wolfberry, 60 to 100 parts of radix rehmanniae preparata, 45 to 75 parts of glossy privet fruit and 40 to 60 parts of cacumen biotae. The Chinese patent medicine for treating the alopecia provided by the invention is reasonable in prescription, the medicines are fewer but better, the medicines have synergistic effect, and a good effect for treating the alopecia is achieved.
Description
Technical field
The present invention relates to the field of Chinese medicines, and in particular to a kind of Chinese medicine composition of hair growth and preparation method thereof.
Background technology
Alopecia refers to the phenomenon of epilation.The normal hair for coming off is at the hair of catagen and stand-down, by
Dynamic equilibrium is constantly in the new hair for entering growth period in catagen is entered, therefore the hair of normal quantity can be maintained.Pathology
Property alopecia refers to that hair is abnormal or excessive to come off, and its reason is a lot.
Etiological：
1. androgenetic alopecia
It is autosomal dominant inheritance, its hereditary feature need to just be showed under androgenic effect；
2. nervous baldness
Usually occur alopecia when stress is excessive to increase.In the presence of stress, human body arrectores pilorum shrinks, hair is straight
Vertical, vegetative nerve or nervous centralis function get muddled, and hair follicle papilla changes and malnutritive, so as to cause hair to be given birth to
Function inhibitio long, hair occurs alopecia into stand-down；
3. endocrine alopecia
Hair growth is influenceed by various endocrine hormones, so causing hair loss disorders when cryptorrhea occurs, such as produces more
Afterwards, climacteric alopecia；
4. trophism alopecia
Hair is the external manifestation of health, and body is malnutritive and pathobolism can cause changing for hair quality and color development
Become, severe malnutrition even results in alopecia generalisata；
5. physical alopecia
The common physical factor for causing alopecia includes mechanical irritation and contact radioactive substance；
6. alopecia of chemical origin
Chemical factor can cause hair color to change even alopecia；
7. infectious alopecia
The infection of various pathogen is a class key factor in hair follicle disease, mainly including bacterium, virus, fungi, conveyor screw, post
It is infested to wait infection；
8. symptomatic alopecia
Some systematicness or local diseases can all occur together alopecia；
9. congenital alopecia
Hair caused by developmental defect is lacked or sparse completely, and the common hair sparse of patient is tiny, or hair is normal during birth,
Shortly come off and do not regenerate, isolated defects and other deformities can be divided into；
10. seasonal alopecia
General summer easy alopecia, because summer temperature pore expansion high causes alopecia, is difficult alopecia, because at this moment when the autumn and winter
Phase temperature drop pore is closed.
The content of the invention
In view of the shortcomings of the prior art, the invention provides a kind of hair growth of determined curative effect Chinese medicine composition and its
Preparation method and application.
To realize object above, the present invention is achieved by the following technical programs：
A kind of Chinese medicine composition of hair growth, is made up of the raw material of following weight portion：Radix Angelicae Sinensis 50-80 parts, glutinous rehmannia 30-60 parts,
Ligusticum wallichii 15-45 parts, mulberries 30-60 parts, Radix Astragali 50-80 parts, Semen sesami nigrum 60-100 parts, mulberry leaf 15-45 parts, prepared fleece flower root 60-100
Part, fruit of Chinese wolfberry 50-80 parts, prepared rhizome of rehmannia 60-100 parts, fruit of glossy privet 45-75 parts, cacumen biotae 40-60 parts.
Preferably, it is made up of the raw material of following weight portion：60 parts of Radix Angelicae Sinensis, 50 parts of glutinous rehmannia, 45 parts of Ligusticum wallichii, 40 parts of mulberries, Huang
70 parts of stilbene, 80 parts of Semen sesami nigrum, 45 parts of mulberry leaf, 80 parts of prepared fleece flower root, 70 parts of the fruit of Chinese wolfberry, 70 parts of prepared rhizome of rehmannia, 75 parts of the fruit of glossy privet, arbor-vitae
40 parts of leaf.
The preparation method of the Chinese medicine composition of hair growth, comprises the following steps：
1) prepared fleece flower root 30g, Radix Angelicae Sinensis, cacumen biotae, Ligusticum wallichii, prepared fleece flower root are taken and is ground into fine powder, it is standby；
2) remaining medicine and remaining prepared fleece flower root, the refluxing extraction that adds water 2 times, each 2h, filtering, merge extract solution, filtration, filtrate
It is 1.05~1.10 to be condensed into relative density（70~80 DEG C）Clear cream；
3) fine powder and other auxiliary materials 1) is added in clear cream, is mixed, be made particle, dried；
4) pharmaceutically acceptable carrier is added thereto to, corresponding pharmaceutical dosage form is prepared into.
Preferably, the formulation is tablet, granule, suppository, capsule or pill.
The Chinese medicine composition of hair growth as the active ingredient of the medicine of hair growth application.
Beneficial effect of the present invention：Each raw material Chinese medicine is complemented each other in the present invention, synergy, and heat-clearing and damp-drying drug, desinsection are played altogether
Antipruritic effect, has definite curative effect for alopecia, and evident in efficacy, has no side effect safely, there is good popularizing value.
Specific embodiment
To make the purpose, technical scheme and advantage of the embodiment of the present invention clearer, below in conjunction with the embodiment of the present invention,
Technical scheme in the embodiment of the present invention is clearly and completely described, it is clear that described embodiment is the present invention one
Divide embodiment, rather than whole embodiments.Based on the embodiment in the present invention, those of ordinary skill in the art are not making
The every other embodiment obtained under the premise of creative work, belongs to the scope of protection of the invention.
Embodiment 1：
A kind of Chinese medicine composition of hair growth, is made up of the raw material of following weight portion：60 parts of Radix Angelicae Sinensis, 50 parts of glutinous rehmannia, Ligusticum wallichii 45
Part, 40 parts of mulberries, 70 parts of the Radix Astragali, 80 parts of Semen sesami nigrum, 45 parts of mulberry leaf, 80 parts of prepared fleece flower root, 70 parts of the fruit of Chinese wolfberry, 70 parts of prepared rhizome of rehmannia,
75 parts of the fruit of glossy privet, 40 parts of cacumen biotae.
The preparation method of the Chinese medicine composition of hair growth, comprises the following steps：
1) prepared fleece flower root 30g, Radix Angelicae Sinensis, cacumen biotae, Ligusticum wallichii, prepared fleece flower root are taken and is ground into fine powder, it is standby；
2) remaining medicine and remaining prepared fleece flower root, the refluxing extraction that adds water 2 times, each 2h, filtering, merge extract solution, filtration, filtrate
It is 1.05~1.10 to be condensed into relative density（70~80 DEG C）Clear cream；
3) fine powder and other auxiliary materials 1) is added in clear cream, is mixed, be made particle, dried；
4) pharmaceutically acceptable carrier is added thereto to, piece agent 1000 is prepared.
Embodiment 2：
A kind of Chinese medicine composition of hair growth, is made up of the raw material of following weight portion：50 parts of Radix Angelicae Sinensis, 55 parts of glutinous rehmannia, Ligusticum wallichii 50
Part, 40 parts of mulberries, 60 parts of the Radix Astragali, 80 parts of Semen sesami nigrum, 45 parts of mulberry leaf, 70 parts of prepared fleece flower root, 60 parts of the fruit of Chinese wolfberry, 70 parts of prepared rhizome of rehmannia,
70 parts of the fruit of glossy privet, 40 parts of cacumen biotae.
The preparation method of the Chinese medicine composition of hair growth, comprises the following steps：
1) prepared fleece flower root 30g, Radix Angelicae Sinensis, cacumen biotae, Ligusticum wallichii, prepared fleece flower root are taken and is ground into fine powder, it is standby；
2) remaining medicine and remaining prepared fleece flower root, the refluxing extraction that adds water 2 times, each 2h, filtering, merge extract solution, filtration, filtrate
It is 1.05~1.10 to be condensed into relative density（70~80 DEG C）Clear cream；
3) fine powder and other auxiliary materials 1) is added in clear cream, is mixed, be made particle, dried；
4) pharmaceutically acceptable carrier is added thereto to, 1000 bags of granule is prepared into.
Embodiment 3：
A kind of Chinese medicine composition of hair growth, is made up of the raw material of following weight portion：65 parts of Radix Angelicae Sinensis, 40 parts of glutinous rehmannia, Ligusticum wallichii 45
Part, 45 parts of mulberries, 70 parts of the Radix Astragali, 60 parts of Semen sesami nigrum, 55 parts of mulberry leaf, 60 parts of prepared fleece flower root, 70 parts of the fruit of Chinese wolfberry, 70 parts of prepared rhizome of rehmannia,
65 parts of the fruit of glossy privet, 40 parts of cacumen biotae.
The preparation method of the Chinese medicine composition of hair growth, comprises the following steps：
1) prepared fleece flower root 30g, Radix Angelicae Sinensis, cacumen biotae, Ligusticum wallichii, prepared fleece flower root are taken and is ground into fine powder, it is standby；
2) remaining medicine and remaining prepared fleece flower root, the refluxing extraction that adds water 2 times, each 2h, filtering, merge extract solution, filtration, filtrate
It is 1.05~1.10 to be condensed into relative density（70~80 DEG C）Clear cream；
3) fine powder and other auxiliary materials 1) is added in clear cream, is mixed, be made particle, dried；
4) pharmaceutically acceptable carrier is added thereto to, capsule 1000 is prepared into.
Embodiment 4：
A kind of Chinese medicine composition of hair growth, is made up of the raw material of following weight portion：60 parts of Radix Angelicae Sinensis, 55 parts of glutinous rehmannia, Ligusticum wallichii 44
Part, 40 parts of mulberries, 75 parts of the Radix Astragali, 70 parts of Semen sesami nigrum, 45 parts of mulberry leaf, 80 parts of prepared fleece flower root, 60 parts of the fruit of Chinese wolfberry, 60 parts of prepared rhizome of rehmannia,
70 parts of the fruit of glossy privet, 45 parts of cacumen biotae.
The preparation method of the Chinese medicine composition of hair growth, comprises the following steps：
1) prepared fleece flower root 30g, Radix Angelicae Sinensis, cacumen biotae, Ligusticum wallichii, prepared fleece flower root are taken and is ground into fine powder, it is standby；
2) remaining medicine and remaining prepared fleece flower root, the refluxing extraction that adds water 2 times, each 2h, filtering, merge extract solution, filtration, filtrate
It is 1.05~1.10 to be condensed into relative density（70~80 DEG C）Clear cream；
3) fine powder and other auxiliary materials 1) is added in clear cream, is mixed, be made particle, dried；
4) pharmaceutically acceptable carrier is added thereto to, pill 1000 is prepared into.
Embodiment 5：
A kind of Chinese medicine composition of hair growth, is made up of the raw material of following weight portion：70 parts of Radix Angelicae Sinensis, 58 parts of glutinous rehmannia, Ligusticum wallichii 45
Part, 40 parts of mulberries, 74 parts of the Radix Astragali, 80 parts of Semen sesami nigrum, 45 parts of mulberry leaf, 60 parts of prepared fleece flower root, 80 parts of the fruit of Chinese wolfberry, 70 parts of prepared rhizome of rehmannia,
70 parts of the fruit of glossy privet, 40 parts of cacumen biotae.
The preparation method of the Chinese medicine composition of hair growth, comprises the following steps：
1) prepared fleece flower root 30g, Radix Angelicae Sinensis, cacumen biotae, Ligusticum wallichii, prepared fleece flower root are taken and is ground into fine powder, it is standby；
2) remaining medicine and remaining prepared fleece flower root, the refluxing extraction that adds water 2 times, each 2h, filtering, merge extract solution, filtration, filtrate
It is 1.05~1.10 to be condensed into relative density（70~80 DEG C）Clear cream；
3) fine powder and other auxiliary materials 1) is added in clear cream, is mixed, be made particle, dried；
4) pharmaceutically acceptable carrier is added thereto to, soft capsule 1000 is prepared into.
Claims (5)
1. a kind of Chinese medicine composition of hair growth, it is characterised in that be made up of the raw material of following weight portion：Radix Angelicae Sinensis 50-80 parts,
Glutinous rehmannia 30-60 parts, Ligusticum wallichii 15-45 parts, mulberries 30-60 parts, Radix Astragali 50-80 parts, Semen sesami nigrum 60-100 parts, mulberry leaf 15-45 parts, system
Fleece-flower root 60-100 parts, fruit of Chinese wolfberry 50-80 parts, prepared rhizome of rehmannia 60-100 parts, fruit of glossy privet 45-75 parts, cacumen biotae 40-60 parts.
2. the Chinese medicine composition of hair growth as claimed in claim 1, it is characterised in that by the raw material system of following weight portion
Into：60 parts of Radix Angelicae Sinensis, 50 parts of glutinous rehmannia, 45 parts of Ligusticum wallichii, 40 parts of mulberries, 70 parts of the Radix Astragali, 80 parts of Semen sesami nigrum, 45 parts of mulberry leaf, prepared fleece flower root
80 parts, 70 parts of the fruit of Chinese wolfberry, 70 parts of prepared rhizome of rehmannia, 75 parts of the fruit of glossy privet, 40 parts of cacumen biotae.
3. the preparation method of the Chinese medicine composition of hair growth as claimed in claim 1 or 2, it is characterised in that including following
Step：
1) prepared fleece flower root 30g, Radix Angelicae Sinensis, cacumen biotae, Ligusticum wallichii, prepared fleece flower root are taken and is ground into fine powder, it is standby；
2) remaining medicine and remaining prepared fleece flower root, the refluxing extraction that adds water 2 times, each 2h, filtering, merge extract solution, filtration, filtrate
It is 1.05~1.10 to be condensed into relative density（70~80 DEG C）Clear cream；
3) fine powder and other auxiliary materials 1) is added in clear cream, is mixed, be made particle, dried；
4) pharmaceutically acceptable carrier is added thereto to, corresponding pharmaceutical dosage form is prepared into.
4. the preparation method of the Chinese medicine composition of hair growth as claimed in claim 3, it is characterised in that the formulation is piece
Agent, granule, capsule or pill.
5. the Chinese medicine composition of hair growth as claimed in claim 1 or 2 as the active ingredient of the medicine of hair growth should
With.
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Cited By (2)
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|---|---|---|---|---|
| CN110628560A (en) * | 2018-06-21 | 2019-12-31 | 苗力公 | Health vinegar for blackening hair, preventing alopecia and delaying aging and preparation method thereof |
| CN114848712A (en) * | 2021-06-17 | 2022-08-05 | 郑州市盛和远生物科技有限公司 | Traditional Chinese medicine liquid for changing white hair into black hair and preparation method thereof |
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2017
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|---|---|---|---|---|
| CN110628560A (en) * | 2018-06-21 | 2019-12-31 | 苗力公 | Health vinegar for blackening hair, preventing alopecia and delaying aging and preparation method thereof |
| CN114848712A (en) * | 2021-06-17 | 2022-08-05 | 郑州市盛和远生物科技有限公司 | Traditional Chinese medicine liquid for changing white hair into black hair and preparation method thereof |
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