CN106692309A - Traditional Chinese medicinal formula for treating angina pectoris - Google Patents

Traditional Chinese medicinal formula for treating angina pectoris Download PDF

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CN106692309A
CN106692309A CN201611017024.3A CN201611017024A CN106692309A CN 106692309 A CN106692309 A CN 106692309A CN 201611017024 A CN201611017024 A CN 201611017024A CN 106692309 A CN106692309 A CN 106692309A
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chinese medicine
medicine preparation
traditional chinese
chinese medicinal
radix
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李怀鹏
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/02—Medicinal preparations containing materials or reaction products thereof with undetermined constitution from inanimate materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/618—Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/21—Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236—Ligusticum (licorice-root)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258—Panax (ginseng)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284—Atractylodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286—Carthamus (distaff thistle)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/29—Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
    • A61K36/296—Epimedium
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/34—Campanulaceae (Bellflower family)
    • A61K36/344—Codonopsis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481—Astragalus (milkvetch)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/482—Cassia, e.g. golden shower tree
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/487—Psoralea
    • A—HUMAN NECESSITIES
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537—Salvia (sage)
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A61K36/638—Ligustrum, e.g. Chinese privet
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/74—Rubiaceae (Madder family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/84—Valerianaceae (Valerian family), e.g. valerian
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    • A61K36/88—Liliopsida (monocotyledons)
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    • A61K36/8988—Gastrodia
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    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/902—Sparganiaceae (Bur-reed family)
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches

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Abstract

The invention discloses a traditional Chinese medicinal formula for treating angina pectoris. The traditional Chinese medicinal formula is prepared from the following traditional Chinese medicinal components in parts by weight: 16g of herba epimedii, 16g of herba taxilli, 18g of fructus ligustri Lucidi, 16g of fructus psoraleae, 16g of radix cyathulae, 18g of radix salviae miltiorrhizae, 3g of radix notoginseng powder, 16g of lignum santali albi, 11g of rhizoma chuanxiong and 11g of Chinese angelica. A preparation and use method of a traditional Chinese medicinal composition disclosed by the invention is that the traditional Chinese medicinal composition is decocted with water for taking, with one dose each day and 7 doses as one treatment course and 2 to 6 treatment courses are required.

Description

One kind treats anginal Chinese medicine preparation
Technical field
It is to be related to a kind of treat anginal Chinese medicine preparation specifically the invention belongs to Chinese medicine composition.
Background technology
Angina pectoris refer to because coronary atherosclerosis cause coronary insufficiency, myocardium ischemia with With precordialgia as main clinical manifestation one group of syndrome caused by anoxic.Its feature is the shirtfront squeezing property of paroxysmal Sensation of pain, can be with other symptoms, and pain is predominantly located at breastbone rear portion, can be radiated to pareordia and left upper extremity, often betides When working or be excited, last for several minutes is rested or is disappeared with after nitrate preparations.This disease is more common in male, most patients It is tired, excited more than 40 years old, it to be satiated with food, catches cold, rainy weather, acute circulatory failure etc. is common inducement.The property heart Angina should squeeze to tighten, compressing asphyxia, and heavy vexed swollen property pain is frequently located in breastbone or its is neighbouring outside tract pain or discomfort, May also occur at upper abdomen to any level between pharyngeal.Risk factor is secondly excited based on physical fatigue, is stepped on Building, level land skelps, and exposed to cold environment, enters cold drink, the pain at other positions of body, and terrified, anxiety, gets angry, and is tired of The emotional change such as angry, can all induce.Symptom being treated Western medicine, it is impossible to effectively treat the disease, and utilize Chinese herbal treatment, with peace more Entirely, effective advantage.
The present invention is used to treat the Chinese medicine preparation of angina pectoris nursing, for angina pectoris etiology and pathogenesis, with clearing heat and detoxicating, heat-clearing Dampness removing, cleaning heat and expelling wind, restore menstrual flow and invigorate blood circulation, promoting circulation of blood detumescence, promoting blood circulation to remove blood stasis, dissipating bind dredging collateral be the rules for the treatment of, reach cold dispelling Wen Yang, promote blood circulation only Bitterly, anginal effect is treated.
The content of the invention
Present invention aim to address the problem in prior art, spy provide a kind of effect substantially, the course for the treatment of is shorter controls Treat anginal Chinese medicine preparation.
In order to realize foregoing invention purpose, the present invention is made the raw material composition and its weight proportion of the effective ingredient For：Barrenwort 16g, Ramulus Taxilli 16g, fruit of glossy privet 18g, Psoralea corylifolia 16g, radix cyathulae 16g, red sage root 18g, Radix Notoginseng powder 3g, santal 16g, Ligusticum wallichii 11g, Radix Angelicae Sinensis 11g.The preparation and application of Chinese medicine composition of the present invention：It is decocted in water for oral dose：Daily 1 dose, 7 doses is a treatment Journey is, it is necessary to the medication 2-6 courses for the treatment of.
Invent for treating anginal Chinese medicine preparation, natural drug is selected, for angina pectoris etiology and pathogenesis, ingredients Respectively have its effect, coordinate mutually, Ramulus Taxilli kidney qi is flat in side mends；Kidney tonifying that barrenwort, Psoralea corylifolia are supporing yang；Fruit of glossy privet enriching yin and nourishing kidney；River Root of bidentate achyranthes kidney tonifying is stimulated the menstrual flow；The red sage root, Ligusticum wallichii, Radix Angelicae Sinensis, pseudo-ginseng blood-circulation-invigovating stagnation resolvation, santal analgesic qi-regulating.Above-mentioned all herbal medicines are shared, mutually association With bringing out the best in each other, play altogether clearing heat and detoxicating, clearing heat and promoting diuresis, cleaning heat and expelling wind, restore menstrual flow and invigorate blood circulation, promoting circulation of blood detumescence, promoting blood circulation to remove blood stasis, dissipating bind dredging collateral Effect, reach the work of stasis of blood blood, unobstructed vessel, phlegm network leads to, and treats anginal effect.
Specific embodiment
Embodiment 1：It is a kind of to treat anginal Chinese medicine preparation, by weight including following traditional Chinese medicine ingredients：Barrenwort 16g, Ramulus Taxilli 16g, fruit of glossy privet 18g, Psoralea corylifolia 16g, radix cyathulae 16g, red sage root 18g, Radix Notoginseng powder 3g, santal 16g, Ligusticum wallichii 11g, Radix Angelicae Sinensis 11g.
Embodiment 2：If patient has deficiency of vital energy symptom, Radix Astragali 10g, bighead atractylodes rhizome 15g, Radix Codonopsis 15g are added in said components.
Embodiment 3：If patient has extravasated blood symptom, peach kernel 10g, safflower 15g, Mitsubishi 10g are added in said components.
Embodiment 4：If patient has hypertension symptom, yncaria stem with hooks 10g, rhizoma Gastrodiae 15g, cassia seed 10g are added in said components.
Embodiment 5：If patient has arrhythmia cordis symptom, keel 10g, oyster 15g, rhizoma nardostachyos 12g are added in said components.
It is decocted in water for oral dose：Daily 1 dose, 7 doses be a course for the treatment of, it is necessary to the medication 2-6 courses for the treatment of.
The clinical therapeutic efficacy of the Chinese medicine preparation for angina pectoris nursing of the present invention is illustrated below by way of practical example.
1st, clinical data
50 patient with angina pectoris, patient's average age 45 ± 20 years old (25~65 years old), meet "《Chinese medical disease Standardization of diagnosis and curative effect》 Angina diagnostic criteria in (State Administration of Traditional Chinese Medicine's promulgation) ", full diagnostics is patient with angina pectoris.
50 patient with angina pectoris all have the symptoms such as pectoralgia, cardiac arrhythmia, heart failure.
Criterion of therapeutical effect
Cure：Clinical symptom disappearance, cardiac muscle detection is normal；
It is effective：Clinical symptoms substantially mitigate, and patient's rhythm of the heart is neat, painless；
It is invalid：Clinical symptoms are without substantially mitigation, exacerbation of symptoms, and it is invalid to be judged to.
3rd, treatment results
After 50 patient with angina pectoris treat 3~4 courses for the treatment of, cure 38, treat effective 8, invalid 2.Treating total effective rate is 93%.
Typical case：
Dragon certain, male, 42 years old, hyperpyrexia up to 40 DEG C, with cough, pectoralgia, cough rusty expectoration.Check：Sanity, in acute disease Hold, flushed face is short of breath, bottom right lung hears and tubular breath sound；X-ray shows：The big sheet shade of bottom right lung, in lung section point Cloth；The visible pneumococcus of Sputum smears.Body temperature is raised, and gas exchanges are obstructed, and cause Respiratory area reduction relevant with pulmonary infection. 6 doses of inventive formulation is taken afterwards, is decocted in water for oral dose, daily 1 dose, daily 3 clothes.Second examines：Spinning sensation substantially mitigates, 12 doses of following the service, Three examine：Pain elementary solution is removed, and is after treatment effect afterwards, is advised and is continued to take 12 doses.Follow-up 1 year, all goes well.

Claims (5)

1. one kind treats anginal Chinese medicine preparation, it is characterised in that：The Chinese medicine preparation by weight include following Chinese medicine into Point：Barrenwort 16g, Ramulus Taxilli 16g, fruit of glossy privet 18g, Psoralea corylifolia 16g, radix cyathulae 16g, red sage root 18g, Radix Notoginseng powder 3g, santal 16g, Ligusticum wallichii 11g, Radix Angelicae Sinensis 11g.
2. anginal Chinese medicine preparation is treated as claimed in claim 1, it is characterised in that：The Chinese medicine preparation also includes the Radix Astragali 10g, bighead atractylodes rhizome 15g, Radix Codonopsis 15g.
3. anginal Chinese medicine preparation is treated as claimed in claim 1, it is characterised in that：The Chinese medicine preparation also includes peach kernel 10g, safflower 15g, Mitsubishi 10g.
4. anginal Chinese medicine preparation is treated as claimed in claim 1, it is characterised in that：The Chinese medicine preparation also includes yncaria stem with hooks 10g, rhizoma Gastrodiae 15g, cassia seed 10g.
5. anginal Chinese medicine preparation is treated as claimed in claim 1, it is characterised in that：The Chinese medicine preparation also includes keel 10g, oyster 15g, rhizoma nardostachyos 12g.
CN201611017024.3A 2016-11-19 2016-11-19 Traditional Chinese medicinal formula for treating angina pectoris Withdrawn CN106692309A (en)

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Application publication date: 20170524