CN106668327A - Medicine for treating diseases of cerebral nerves and cerebral vessels, and preparation method of medicine - Google Patents
Medicine for treating diseases of cerebral nerves and cerebral vessels, and preparation method of medicine Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/537—Salvia (sage)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/236—Ligusticum (licorice-root)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/285—Aucklandia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/286—Carthamus (distaff thistle)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/533—Leonurus (motherwort)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
- A61K36/638—Ligustrum, e.g. Chinese privet
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
- A61K36/725—Ziziphus, e.g. jujube
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/734—Crataegus (hawthorn)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
- A61K36/815—Lycium (desert-thorn)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
Abstract
The invention discloses a medicine for treating diseases of cerebral nerves and cerebral vessels, and a preparation method of the medicine. The medicine is prepared from the following main raw materials: radix salviae miltiorrhizae, motherwort herb, fructus crataegi, rhizoma chuanxiong, safflower, radix astragali seu hedysari, fructus lycii, glossy privet fruit, herba saussureae involucratae, Chinese angelica, semen ziziphi spinosae, and the like. The medicine aims at dissolving blood stasis and thrombus, softening blood vessels, reducing blood pressure and blood fat, adjusting blood glucose content, improving myocardial blood supply and improving the immunologic function, also has the effects of improving microcirculation, recovering the myocardial function, adjusting and improving the endocrine function of heart, brain and kidney, adjusting the functions of the cerebral nerves and resisting aging, is stable and lasting in curative effect and enables relapse to be uneasy to occur after healing; furthermore, the medicine is a pure traditional Chinese medicine biological preparation, and is rapid in absorption, quick in response, high in content of effective components, less in dose, good in taste, safe and free from toxic and side effects.
Description
Technical field
The present invention relates to technical field of traditional Chinese medicines, more particularly to a kind of medicine and preparation for treating cranial nerve and cranial vascular disease
Method.
Background technology
Encephalopathic is a kind of common disease, and it is most strong to charge power, incidence of disease highest, rate of dieing highest.Through investigating in the world 40
Multiple country's various diseases to cause to die and come front three in rate, because the number that hemiplegia is die accounts for the 22.6% of annual total death toll.
The whole world will at least seize the life of more than 10,000,000 people every year, so the disease is acknowledged as one of " four big killers ".In heart and brain
The preventing and treating aspect of vascular diseases, although the interventional therapy of modern medicine, surgical operation, statin drop ester medicine, anti-platelet agent and
Thrombolytic agent is applied to clinic, but curative effect is not ideal enough, and simply having reached expansion of blood vessels improves the temporary curative effect of circulation, right
Come off patch or the thrombus etc. of flowing dissolves without too big effect in blood vessel, it is difficult to thrombolysis；And commonly using such west
Medicine is easily caused arterial blood tube wall flexibility decrease, and fragility increases, and causes cerebral infarction to be progressively converted into cerebral hemorrhage serious attack again,
Greater area of infraction is caused, it is difficult to cure, and small number of patients occurs adverse reaction after, side effect is larger, clinical
Cure rate is undesirable.Therefore, medicine still Shortcomings for the treatment of angiocardiopathy at present.
The content of the invention
The medicine for treating cranial nerve and cranial vascular disease and preparation it is an object of the present invention to provide a kind of effect is significant
Method.
In order to solve the above technical problems, the present invention provides following technical scheme：
A kind of medicine for treating cranial nerve and cranial vascular disease, the raw material of the medicine constitutes and is：Red sage root 15-25 weight
Part, motherwort 10-15 weight portions, hawthorn 10-15 weight portions, rhizome of chuanxiong 5-10 weight portions, safflower 8-20 weight portions, Radix Astragali 10-20
Weight portion, matrimony vine 10-15 weight portions, fruit of glossy privet 10-15 weight portions, lanatechead saussurea herb with flower 10-20 weight portions, Radix Angelicae Sinensis 10-15 weight portions, acid
Jujube kernel 10-15 weight portions.
Further optimization, the raw material of the medicine constitutes and is：The weight portion of the red sage root 20, the weight portion of motherwort 16, the weight of hawthorn 14
Part, the weight portion of rhizome of chuanxiong 6, the weight portion of safflower 15, the weight portion of the Radix Astragali 15, the weight portion of matrimony vine 12, the weight portion of the fruit of glossy privet 12, lanatechead saussurea herb with flower 15
Weight portion, the weight portion of Radix Angelicae Sinensis 12, the weight portion of spina date seed 12.
The present invention also provides the preparation method of said medicine, comprises the following steps：
1) proportioning weighs each component and is put into container by weight, adds 8 times of distilled water immersions of amount 30 minutes, boils
30min, pours out liquid standby；
2) boil and 20min is decocted in 30min decocting medicine pots to 8 times of distilled water of amount are added in container again, pour out liquid standby
With；
3) 4 times of distilled water of amount are added in most backward container, is boiled and 20min is decocted in 20min decocting medicine pots, pour out liquid standby
With；
4) gained liquid in step 1-3 is well mixed, concentration, sterilization packaging.
The red sage root：It is inducing meastruation to relieve menalgia with promoting blood circulation, relieving restlessness that clears away heart-fire, the effect of cool blood to disappear carbuncle.For chest impediment and cardialgia, gastral cavity abdomen
Hypochondriac pain, the accumulation of lump in the abdomen lump in the abdomen, hot numbness pain, dysphoria and insomnia, irregular menstruation, dysmenorrhoea Amenorrhea, sore swell and ache curative.
Motherwort：Bitter cold in nature, with well regulation menstruation and promoting blood circulation effect, in addition also have dissolving stasis with
And analgesic, the effect that reduces blood pressure, take the size that can be good at expanding body medium vessels after motherwort, effective regulation
Adrenergic secretion, also has good adjustment effect for internal microcirculation.
Hawthorn：Hawthorn not only only has our daily known food digesting actions, while his effect promoting blood circulation and removing blood stasis is also
It is very good.Take hawthorn to can be good at reducing blood pressure and blood clotting, in addition antibacterial, the effect of calm and cardiac stimulant
Really.
Rhizome of chuanxiong：This product is the dry rhizome of samphire Ligusticum wallichii.From Ligusticum wallichii because its pungent, temperature, tool blood-activating and qi-promoting,
Effect of wind-expelling pain-stopping.Modern Chinese herbal medicine thinks that the Chuanxiong bioalkali in Ligusticum wallichii can benumb nervous centralis, and antalgic and sedative, excitement is exhaled
Suction maincenter, vasomotor center, directly expand peripheral vessels, increase the CBF of coronary blood flow and lower limb body, reduce
Cholesterol, reduction blood fat, hypotensive；Extent of platelet aggregation can also be reduced, promotes the dissolving of blood inner fibrin, anti-hemostasis
Bolt, there is spasmolysis.In this prescription, Ligusticum wallichii is rich in active alkaloid, dandelion is improved sanguimotor effect brighter
It is aobvious, promote each prescription medicine complementation to strengthen, curative effect is improved, collaboration reaches effect of radical cure cardiovascular and cerebrovascular disease.
Safflower：Taking safflower can play a part of analgesic and dredging the channel, and the blood vessel in effective expansion body is reduced
Possibility with hypertension, and also can be good at suppress body there is the too fast situation of heart rate, it is ensured that it is healthy.
The Radix Astragali：Enhancing body's immunity, liver protection, diuresis, anti-aging, resisting stress, step-down and wide antibacterial action.
Jishengshenqiwan albuminuria can be eliminated, strengthens myocardial contractive power, adjust blood-sugar content.The Radix Astragali can not only coronary artery dilator, change
Kind myocardial blood supply, improves immunologic function, and be capable of the process of delaying cell aging.
Matrimony vine：It is improved immune function of human body, prevention and suppresses tumour and the prevention of arterial effect such as atherosis, there is antioxygen
Change, anti-aging effects, can also promote hematopoiesis, reduce blood sugar, there is certain antihypertensive effect.
The fruit of glossy privet：Anti-aging, antifatigue, effective reduction blood fat concentration reduces the incidence of artery sclerosis.
Lanatechead saussurea herb with flower：Alias Saussurea involucrata, is the wounded in the battle complete stool of feverfew saussurea medusa flower.Its main component is rue
Glucoside, xuelianlactone, alkaloid, volatile oil, polysaccharide.Lanatechead saussurea herb with flower has warming kidney and enhancing body, warming channel and expelling cold, Wenfei of drink, dispelling wind and eliminating dampness
Effect.
Radix Angelicae Sinensis：The effect invigorated blood circulation and enrich blood, in addition, when giving back the effect with reduction blood fat and blood pressure, energy
The size of enough all blood vessels of effective expansion, increases the CBF in coronary artery, has during for some arrhythmia cordis well
Curative effect.
Spina date seed：It is mild-natured, sweet, acid.Return liver warp, gallbladder channel, the heart channel of Hang-Shaoyin.Tonifying liver, calming heart, arrest sweating, promote the production of body fluid.Category sedative subordinate
The heart-nourishing tranquilizer of classification.With controlling restlessness of asrhenia type and insomnia, horrified to much dream, body void hidrosis, injury thirst.With tranquilizing soporific, calm drop
Warm, anticonvulsion, step-down, anti-heart function.
Pharmaceutical composition of the present invention has extensive pharmacology and physiologically active, specifically has the beneficial effect that：Dissolve hemostasis and
Thrombus, softening blood vessel, reduce blood pressure blood fat, adjusts blood-sugar content, improves myocardial blood supply, improves immunologic function, and can prolong
The process of slow cell ageing, improves microcirculation, recovers myocardial function, regulation and improvement heart and brain kidney endocrine function, adjusts brain
The effect of nervous function, anti-aging, curative effect stabilization is lasting, the recurrence after healing can be avoided；Additionally, the present invention is pure Chinese medicine biological agent, inhale
Receive that fast, drug effect is rapid, active constituent content is high, dose is few, it is features good taste, safe and free of toxic and side effects.
Specific embodiment
Further supplement, but do not limit the invention in any way are done to the present invention with reference to specific embodiment.
Embodiment 1
The raw material and weight of medicine of the present invention be：
Red sage root 20g, motherwort 16g, hawthorn 14g, rhizome of chuanxiong 6g, safflower 15g, Radix Astragali 15g, matrimony vine 12g, fruit of glossy privet 12g, snow
Lotus flower 15g, Radix Angelicae Sinensis 12g, spina date seed 12g.
Preparation method is as follows：
1) proportioning weighs each component and is put into container by weight, adds 8 times of distilled water immersions of amount 30 minutes, boils
30min, pours out liquid standby；
2) boil and 20min is decocted in 30min decocting medicine pots to 8 times of distilled water of amount are added in container again, pour out liquid standby
With；
3) 4 times of distilled water of amount are added in most backward container, is boiled and 20min is decocted in 20min decocting medicine pots, pour out liquid standby
With；
4) gained liquid in step 1-3 is well mixed, concentration, sterilization packaging.
Usage and dosage：Orally, take after meal；3 times a day, it is within ten days a course for the treatment of, six to eight courses for the treatment of can healing, the state of an illness
Severe patient is followed the doctor's advice the meal with wine amount of adding, and pregnant woman's disabling, sportsman uses with caution.
Embodiment 2
The raw material of medicine of the present invention is constituted and weight is：
Red sage root 16g, motherwort 11g, hawthorn 12g, rhizome of chuanxiong 5g, safflower 10g, Radix Astragali 12g, matrimony vine 10g, fruit of glossy privet 10g, snow
Lotus flower 10g, Radix Angelicae Sinensis 11g, spina date seed 11g.
The present embodiment Chinese medicine preparation preparation method processing step and usage and dosage are same as Example 1.
Embodiment 3
Red sage root 23g, motherwort 14g, hawthorn 13g, rhizome of chuanxiong 9g, safflower 18g, Radix Astragali 17g, matrimony vine 14g, fruit of glossy privet 13g, snow
Lotus flower 19g, Radix Angelicae Sinensis 13g, spina date seed 13g.
The present embodiment Chinese medicine preparation preparation method processing step and usage and dosage are same as Example 1.
Moreover, it will be appreciated that although the present specification is described in terms of embodiments, not each implementation method is only wrapped
Containing an independent technical scheme, this narrating mode of specification is only that for clarity, those skilled in the art should
Specification an as entirety, the technical scheme in each embodiment can also be formed into those skilled in the art through appropriately combined
May be appreciated other embodiment.
Claims (3)
1. a kind of medicine for treating cranial nerve and cranial vascular disease, it is characterised in that：The raw material of the medicine is constituted：Red sage root 15-
25 weight portions, motherwort 10-15 weight portions, hawthorn 10-15 weight portions, rhizome of chuanxiong 5-10 weight portions, safflower 8-20 weight portions, the Radix Astragali
10-20 weight portions, matrimony vine 10-15 weight portions, fruit of glossy privet 10-15 weight portions, lanatechead saussurea herb with flower 10-20 weight portions, Radix Angelicae Sinensis 10-15 weight
Part, spina date seed 10-15 weight portions.
2. a kind of medicine for treating cranial nerve and cranial vascular disease according to claim 1, it is characterised in that：The medicine
Raw material is constituted：The weight portion of the red sage root 20, the weight portion of motherwort 16, the weight portion of hawthorn 14, the weight portion of rhizome of chuanxiong 6, the weight portion of safflower 15,
The weight portion of the Radix Astragali 15, the weight portion of matrimony vine 12, the weight portion of the fruit of glossy privet 12, the weight portion of lanatechead saussurea herb with flower 15, the weight portion of Radix Angelicae Sinensis 12, spina date seed 12
Weight portion.
3. the preparation method of medicine according to claim 1, it is characterised in that：Including step：
1) proportioning weighs each component and is put into container by weight, adds 8 times of distilled water immersions of amount 30 minutes, boils
30min, pours out liquid standby；
2) boil and 20min is decocted in 30min decocting medicine pots to 8 times of distilled water of amount are added in container again, pour out liquid standby；
3) 4 times of distilled water of amount are added in most backward container, is boiled and 20min is decocted in 20min decocting medicine pots, pour out liquid standby；
4) gained liquid in step 1-3 is well mixed, concentration, sterilization packaging.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201710139267.2A CN106668327A (en) | 2017-03-09 | 2017-03-09 | Medicine for treating diseases of cerebral nerves and cerebral vessels, and preparation method of medicine |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710139267.2A CN106668327A (en) | 2017-03-09 | 2017-03-09 | Medicine for treating diseases of cerebral nerves and cerebral vessels, and preparation method of medicine |
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1709404A (en) * | 2005-06-21 | 2005-12-21 | 浙江杭州鑫富药业股份有限公司 | Chinese patent medicine for preventing and treating apoplexia disease, and its production method and use |
| CN101336981A (en) * | 2008-08-19 | 2009-01-07 | 吕达 | Medicine for treating hemiparalysis |
| CN101380455A (en) * | 2004-12-27 | 2009-03-11 | 杨俭 | Formulation for treating apoplexy |
-
2017
- 2017-03-09 CN CN201710139267.2A patent/CN106668327A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101380455A (en) * | 2004-12-27 | 2009-03-11 | 杨俭 | Formulation for treating apoplexy |
| CN1709404A (en) * | 2005-06-21 | 2005-12-21 | 浙江杭州鑫富药业股份有限公司 | Chinese patent medicine for preventing and treating apoplexia disease, and its production method and use |
| CN101336981A (en) * | 2008-08-19 | 2009-01-07 | 吕达 | Medicine for treating hemiparalysis |
Non-Patent Citations (1)
| Title |
|---|
| 任树生 等: "《脑卒中诊治、护理与康复》", 31 July 1994, 天津科技翻译出版社 * |
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