CN106667811A - Additive-free skincare cosmetic containing deep purifying factors CPEs - Google Patents
Additive-free skincare cosmetic containing deep purifying factors CPEs Download PDFInfo
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- CN106667811A CN106667811A CN201710159362.9A CN201710159362A CN106667811A CN 106667811 A CN106667811 A CN 106667811A CN 201710159362 A CN201710159362 A CN 201710159362A CN 106667811 A CN106667811 A CN 106667811A
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- Prior art keywords
- skin
- cpes
- natural
- deep purifying
- cosmetic
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/75—Anti-irritant
Abstract
The invention relates to a skincare cosmetic, and in particular to a curative type skincare cosmetic containing deep purifying factors (CPEs). The curative type skincare cosmetic consists of the deep purifying factors (CPEs), hyaluronic acid (fermentation method), natural anti-allergy plant extract, natural anticorrosive and antibacterial plant extract and natural plant water, which are prepared to be a glassy, transparent and slightly viscous watery cosmetic. The curative type skincare cosmetic containing the deep purifying factors (CPEs) disclosed by the invention is a fully natural cosmetic based on natural plants and fermentation products as raw materials, is mild and non-stimulating, has very strong moisturizing and repairing functions to skin, and can effectively relieve damage of environmental pollutions such as haze and the like on the skin.
Description
Technical field
The present invention relates to a kind of cosmetics of skin protection, more specifically to a kind of deep layer purification factor (CPEs) is contained
Curative effect-type skin protection cosmeticss.
Background technology
Cosmetic industry have passed through the aspects such as the development of many decades, products material, formula technique great increase
And lifting.Product efficacy also develops into whitening and speckle dispelling of today, antiallergic defying age, prevents from the simple moisture-keeping efficacy initially only having
Shine reparation etc..
But as the environmental pollutions such as expanding economy, haze are on the rise, have a strong impact on the quality of life of people
With it is healthy.Particularly PM2.5, from rarely known by the people, it is widely known to quickly become.There are some researches show, PM2.5 is to human body skin
Long-term injury can not despise, can not only accelerate the aging of skin, in some instances it may even be possible to cause irreversible injury.
It is no lack of in the market with delay skin aging, removes free radical to protect the cosmetics of skin.But rarely have shield
Skin product can be played to skin in the haze pollution environment being on the rise and be effectively protected and effectively mitigate PM2.5 to skin
Injury.
The content of the invention
Present invention aim at, the deep layer purification factor extracted by chlorella is relied on, coordinate the hyaluronic acid of efficient moisture-retention
(also referred to as hyaluronic acid or nature moisturizing factor NMF) and natural plants hydrosol, for effect that skin provides superpower moisturizing, together
When, effectively mitigate injuries of the PM2.5 to skin, and using natural plants antiallergic and anti-corrosive antibacterial system, make a kind of whole day
So, no added health skin protection cosmeticss.
The present invention seeks to be achieved by the following scheme：Made using the deep layer purification factor (CPEs) extracted from chlorella
For active substance, by with hyaluronic acid, natural antiallergic plant extract, natural anticorrosion antibacterial plant extract and natural plant
According to a certain percentage in a kettle. allotment is formed thing hydrosol.Concrete ratio is (based on production 100kg)：Natural plants hydrosol：
62kg~99.69kg, hyaluronic acid：0.1kg~20kg, CPEs：0.01kg~10kg, natural antiallergic plant extract：0.1kg
~5kg, natural anticorrosion antibacterial plant extract：0.1kg~3kg,.
The deep layer purification factor CPEs for being used takes from chlorella, and is with the ice source chlorella in 4500 meters of glaciers of height above sea level
Good, it is a kind of mixture for containing many kinds of substance such as protein, polysaccharide, nucleic acid, polypeptide, vitamin and trace element, its
Diversified material composition makes it have various skin-care effects：Remove free radical, chelating oxidoreduction heavy metal ion, reinforcing angle
Matter layer barrier, regulation macrophages in vitro immunologic function, repair cell and DNA damage, antipollution, radioprotective and safe nothing
Stimulate.Environmental pollution of today, such as haze, PM2.5, medicated cigarette, vehicle exhaust etc., the damage to human body skin is increasingly serious,
And chlorella deep layer purification factor is resistant to the natural sharp weapon of these pollutions.
Jing researchs confirm that CPEs can be in weights such as cadmium, arsenic, zinc, the lead in the sebum layer of skin surface absorption complexation PM2.5
Metal, and CPEs can quickly be absorbed by skin, penetrate to the skin deep layer, can not only be in the poly- egg of keratodermatitis reinforcement fibre
In vain, repair stratum corneum barrier, can with the reaction that in the phagocytic activity of skin particles layer activating macrophage, diminishes inflammation, and
Cell propagation, DNA plerosis is promoted to damage in the prickle cell layer of skin.
The hyaluronic acid for being used is a kind of acid mucopolysaccharide, and its unique molecular structure and physicochemical property show in body
Various important physiological functions are shown.Particular, it is important that hyaluronic acid has special water retention, be have now been found that from
Right best material of moisture retention in boundary, be referred to as preferable nature moisturizing factor (Natural moisturizing factor,
NMF, for example：The 2% water-soluble liquid energy of pure hyaluronic acid firmly holds 98% moisture).It can make moisture enter intercellular substance, and
Combined with protein and formed protein gel, cell is sticked together, holding cell is played in the cellular metabolism effect brought into normal play
Moisture, protects cell not encroached on by pathogen, accelerates to recover skin histology, improves wound healing regeneration capacity, reduces cicatrix,
Enhancing immunity etc. is acted on.Hyaluronic acid is acted on after the conditioning of skin inside, can be automatically adjusted in different environments, is maintained all the time
Moisture of skin keeps the moistening of skin, salubrious in 25-30%, makes skin more high resilience, plays crease-resistant wrinkle resistant, delaying skin
Aging, the effect of looks improving and the skin nourishing.
The natural antiallergic plant extract for being used is such as：Natural Herba bromi japonici anti-sensitizer (SK-Calmin skins are quick to relax), containing Fructus psidii guajavae immaturus
Leaf, tea, the efficient antiallergic of Flos Rosae Rugosae extract repair mixture GLCE etc..
The natural anticorrosion antibacterial plant extract for being used is such as：The bark extract of magnolia obovata containing Folium Psidii Guajavae
CosphadermGMG, the EURO-NapreEX containing grapefruit seed and Radix Scutellariae root extract etc..
The natural plants hydrosol for being used includes：MEIGUI CHUNLU, Garden lavender hydrosol, chamomile hydrosol etc..Natural plants are pure
Dew takes from the elite of fractional distillation during plants essential oil distillation extraction, the vegetable material that fresh or drying is processed, and puts steam into
In hot melting furnace, the stronger plant fragrance quintessence oil of volatilization is carried out using water vapour, is allowed to form the vapor containing quintessence oil
State, by the conduit of household freezer, using temp-difference condensing into liquid condition, so as to isolate hydrosol water.Incorporate in hydrosol water
Various precious compositions in plant, and containing about 0.3%~0.5% quintessence oil water soluble ingredient, so still possess the virtue of quintessence oil
Fragrant, part curative effect and slight antibiotic property, and containing the unexistent plant essence of quintessence oil (such as tannic acid and flavonoid) so that it is pure
Dew has functions that to nurse one's health skin, and the characteristic of its low concentration is allowed to be easier to be less readily available for absorption by the skin.Such as, MEIGUI CHUNLU can be with bright
White muscle skin, moisture-keeping crease-shedding, slow down aging；Garden lavender hydrosol can control oil, freckle removing and whitening, eye haustra -dsipelling；Chamomile hydrosol
Can releive sensitive skin, calm down the blood capillary of rupture, increase skin elasticity etc..
Compared with existing cosmetics, the product that the present invention makes has advantages below and effect：
1st, the chlorella deep layer purification factor CPEs being rich in product is verified by experiments and can effectively mitigate PM2.5 to human body
The injury of skin：Heavy metal complexation clearance is up to about 24%~54%；0.02% CPEs can make the phagocytic activity of cell
Increase about more than 80%；Cuticle loss reduces about 50%~80%；Silk polyprotein is damaged and reduces about 60%~90%.
Relevant test method is as follows：
Heavy metal complexation is tested：
Accelerated test bar：48 DEG C, 4 DEG C, -18~48 DEG C of alternatings, normal-temperature lights photographs；
Cu2+ removes experiment：Cu2+-1.875mmol/L, pyrocatechol violet -20mmol/L, maximum absorption wavelength 632nm,
Cu chelation percents=[C (before Cu reactions)-C (Cu- samples)]+C (before Cu reactions) X100%；0H clearance rate:Fenton reacts, ginseng
Examine wavelength 630nm, Detection wavelength 550nm, 0H clearance rate=[C (before 0H reactions)-C (0H- samples)]+C (0H reactions
Before) X100%.
Impact experiment to macrophage Ana-1 phagocytic activity：
Take the logarithm the cell of trophophase, piping and druming is made 2*105/mL single cell suspensions, per hole 100yL, is inoculated in 96 holes
Cell plates, abandon culture supernatant after cell attachment, if matched group, dosing group, per group of 6 multiple holes cultivate respectively 24,48,72h
Afterwards, add freshly prepared 0.1%NR and PM2.5 suspensions 20yL per hole, continue to cultivate 3h after gently mixing.Afterwards careful suction is abandoned
Culture fluid containing NR, the NR not swallowed softly is washed away with physiology ros.Add 150yL cell pyrolysis liquid (dehydrated alcohol per hole：
Acetic acid=1:1 (v/v)), 2h is stood, cell is dissolved, concussion determines 0D values at 540nm after mixing.Phagocytic rate of the cell to NR
It is as follows：Phagocytic rate=dosing group/matched group * 100%.
3D skins efficacy assessments experiment (horny layer and silk polyprotein damage check are tested)：
Time：Extract by several times, 1 hour/time, count 2 hours,
Atmospheric condition：Experiment location averagely has daily 700000 ± 300 automobiles to pass through,
Power：Gas chestnut maintains constant flow rate (113 ± 0113m3/ point).
Extraction element：PM reception devices, PM10 filters, the cell culture process film of 3D skins 4, DMEM culture medium 4 are inhaled and are raised
Formula gas chestnut
Experimental procedure：
Prepare three table apparatus, 3 pieces of 3D skins are done into immune labeled.
(1) directly people 3D skins are cultivated 5 days；
(2) PM2.5 is extracted, people 3D skins is cultivated 5 days after 1 hour；
(3) extract PM2.5 again after uniform application sample on 3D skins, 1 hour, cultivate 3D skins 5 days.Use after 5 days
Leica'sQ500 Image Analysis softwares measure tri- kinds of situation servant's 3D skin thickness (cuticle loss detection) of A/B/C；Examine simultaneously
Survey the expression (silk polyprotein damage check) of label silk polyprotein.
2nd, the product formula based on natural plants hydrosol, is aided with the nature moisturizing factor hyaluronic acid of high concentration so that produce
Product have powerful skin moisture-retaining capacity.
3rd, the natural plants antiallergic and anti-corrosive antibacterial system that are adopted ensure that gentle, the health and safety of product.
Specific embodiment
Embodiments of the invention are：
Concocting method is：MEIGUI CHUNLU is placed in reactor, is stirred and is warming up to less than 50 degrees Celsius, then added successively
Enter the quick easypro, EURO-NapreEX of deep layer purification factor CPEs, hyaluronic acid, skin, stir, be gradually cooling to be carried out after room temperature
It is canned.
Products obtained therefrom is crystal clear, slightly sticky watery skin care item, safely, is not gently stimulated, with naturally pleasant
Rose atmosphere, can effectively mitigate the pollution injury of the environment to skin such as haze, meanwhile, there is excellent moisturizing shield to skin
Reason, effect of slow down aging.
Above-described embodiment is the preferably embodiment of the present invention, but embodiments of the present invention do not receive above-described embodiment
Restriction, other any spirit without departing from the present invention and the change, modification, replacement made under principle, combine, it is simple
Change, should be equivalent substitute mode, be included in protection scope of the present invention.
Claims (2)
1. a kind of no added skin protection cosmeticss containing deep layer purification factor CPEs, it is characterised in that including following material composition,
The quality of wherein each composition is respectively：
。
2. no added skin protection cosmeticss containing deep layer purification factor CPEs as claimed in claim 1, it is characterised in that made
Deep layer purification factor is the purification factor extracted by chlorella.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710159362.9A CN106667811A (en) | 2017-03-17 | 2017-03-17 | Additive-free skincare cosmetic containing deep purifying factors CPEs |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710159362.9A CN106667811A (en) | 2017-03-17 | 2017-03-17 | Additive-free skincare cosmetic containing deep purifying factors CPEs |
Publications (1)
| Publication Number | Publication Date |
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| CN106667811A true CN106667811A (en) | 2017-05-17 |
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ID=58829030
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710159362.9A Pending CN106667811A (en) | 2017-03-17 | 2017-03-17 | Additive-free skincare cosmetic containing deep purifying factors CPEs |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109453100A (en) * | 2018-12-29 | 2019-03-12 | 拉芳家化股份有限公司 | A kind of full ingredient natural origin and the lotion without deionized water |
| WO2019051965A1 (en) * | 2017-09-15 | 2019-03-21 | 广州无添加主义化妆品有限公司 | Quality control method for additive-free skin-care mask and application thereof, and method for packaging additive-free skin-care mask |
| CN110179718A (en) * | 2019-07-03 | 2019-08-30 | 广东巴松那生物科技有限公司 | A kind of anthosin droplet dew for purifying skin of refreshing oneself and preparation method thereof |
| CN114224802A (en) * | 2021-12-31 | 2022-03-25 | 上海智勇教育培训有限公司 | Long-acting fresh-keeping skin-care type hydrolat based on natural traditional Chinese medicines and preparation method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102935055A (en) * | 2012-12-04 | 2013-02-20 | 深圳市妍倩科技有限公司 | Hydrolat moisturizing facial mask |
| CN105411919A (en) * | 2015-12-01 | 2016-03-23 | 武汉光阴树生态科技有限公司 | Skin caring product made from roses and preparation method thereof |
| CN106236623A (en) * | 2016-07-29 | 2016-12-21 | 上海伽誉生物科技有限公司 | The preparation method of chlorella deep layer purification factor |
-
2017
- 2017-03-17 CN CN201710159362.9A patent/CN106667811A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102935055A (en) * | 2012-12-04 | 2013-02-20 | 深圳市妍倩科技有限公司 | Hydrolat moisturizing facial mask |
| CN105411919A (en) * | 2015-12-01 | 2016-03-23 | 武汉光阴树生态科技有限公司 | Skin caring product made from roses and preparation method thereof |
| CN106236623A (en) * | 2016-07-29 | 2016-12-21 | 上海伽誉生物科技有限公司 | The preparation method of chlorella deep layer purification factor |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019051965A1 (en) * | 2017-09-15 | 2019-03-21 | 广州无添加主义化妆品有限公司 | Quality control method for additive-free skin-care mask and application thereof, and method for packaging additive-free skin-care mask |
| CN109453100A (en) * | 2018-12-29 | 2019-03-12 | 拉芳家化股份有限公司 | A kind of full ingredient natural origin and the lotion without deionized water |
| CN110179718A (en) * | 2019-07-03 | 2019-08-30 | 广东巴松那生物科技有限公司 | A kind of anthosin droplet dew for purifying skin of refreshing oneself and preparation method thereof |
| CN114224802A (en) * | 2021-12-31 | 2022-03-25 | 上海智勇教育培训有限公司 | Long-acting fresh-keeping skin-care type hydrolat based on natural traditional Chinese medicines and preparation method thereof |
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Application publication date: 20170517 |