CN106663587B - 冲击器喷雾离子源 - Google Patents

冲击器喷雾离子源 Download PDF

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Publication number
CN106663587B
CN106663587B CN201580042818.2A CN201580042818A CN106663587B CN 106663587 B CN106663587 B CN 106663587B CN 201580042818 A CN201580042818 A CN 201580042818A CN 106663587 B CN106663587 B CN 106663587B
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CN
China
Prior art keywords
targets
ion source
structures
gas
stream
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201580042818.2A
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English (en)
Chinese (zh)
Other versions
CN106663587A (zh
Inventor
斯特万·巴伊奇
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Micromass UK Ltd
Original Assignee
Micromass UK Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB1414596.5A external-priority patent/GB201414596D0/en
Application filed by Micromass UK Ltd filed Critical Micromass UK Ltd
Publication of CN106663587A publication Critical patent/CN106663587A/zh
Application granted granted Critical
Publication of CN106663587B publication Critical patent/CN106663587B/zh
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Classifications

    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/10—Ion sources; Ion guns
    • H01J49/14—Ion sources; Ion guns using particle bombardment, e.g. ionisation chambers
    • H01J49/142—Ion sources; Ion guns using particle bombardment, e.g. ionisation chambers using a solid target which is not previously vapourised
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
    • H01J49/0431—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components for liquid samples
    • H01J49/0445—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components for liquid samples with means for introducing as a spray, a jet or an aerosol
    • H01J49/045—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components for liquid samples with means for introducing as a spray, a jet or an aerosol with means for using a nebulising gas, i.e. pneumatically assisted
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/10—Ion sources; Ion guns
    • H01J49/16—Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Plasma & Fusion (AREA)
  • Dispersion Chemistry (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Electron Tubes For Measurement (AREA)
CN201580042818.2A 2014-08-18 2015-08-18 冲击器喷雾离子源 Active CN106663587B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP14181248 2014-08-18
EP14181248.7 2014-08-18
GBGB1414596.5A GB201414596D0 (en) 2014-08-18 2014-08-18 Impactor Spray API source with vortex Generators
GB1414596.5 2014-08-18
PCT/GB2015/052390 WO2016027073A1 (en) 2014-08-18 2015-08-18 Impactor spray ion source

Publications (2)

Publication Number Publication Date
CN106663587A CN106663587A (zh) 2017-05-10
CN106663587B true CN106663587B (zh) 2019-09-27

Family

ID=54011041

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201580042818.2A Active CN106663587B (zh) 2014-08-18 2015-08-18 冲击器喷雾离子源

Country Status (6)

Country Link
US (1) US10262851B2 (enExample)
EP (1) EP3183740B1 (enExample)
JP (2) JP2017526131A (enExample)
CN (1) CN106663587B (enExample)
GB (1) GB2533184B (enExample)
WO (1) WO2016027073A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2567793B (en) * 2017-04-13 2023-03-22 Micromass Ltd A method of fragmenting and charge reducing biomolecules
CN109841485B (zh) * 2017-11-27 2020-05-08 中国科学院大连化学物理研究所 一种利用空气动力学辅助的方法提高离子传输效率的装置
GB201807914D0 (en) * 2018-05-16 2018-06-27 Micromass Ltd Impactor spray or electrospray ionisation ion source
CN110993481B (zh) * 2019-11-13 2022-11-15 上海裕达实业有限公司 基于康达效应的电喷雾电离源辅助电离装置
CN115531790A (zh) * 2022-10-08 2022-12-30 南开大学 一种剧毒紫精类化合物的降解方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013093517A1 (en) * 2011-12-23 2013-06-27 Micromass Uk Limited Interfacing capillary electrophoresis to a mass spectrometer via an impactor spray ionization source
WO2014064399A1 (en) * 2012-10-25 2014-05-01 Micromass Uk Limited Piezo-electric vibration on an in-source surface ionization structure to aid secondary droplet reduction

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3307384B2 (ja) * 1993-12-09 2002-07-24 株式会社日立製作所 液体クロマトグラフ結合型質量分析装置
JP3379510B2 (ja) * 1993-12-09 2003-02-24 株式会社日立製作所 液体クロマトグラフ結合型質量分析装置
EP1550145B1 (en) * 2002-10-10 2018-01-03 Universita' Degli Studi Di Milano Ionization source for mass spectrometry analysis
EP1855306B1 (en) * 2006-05-11 2019-11-13 ISB - Ion Source & Biotechnologies S.R.L. Ionization source and method for mass spectrometry
US9378938B2 (en) * 2012-10-25 2016-06-28 Micromass Uk Limited Reproducibility of impact-based ionization source for low and high organic mobile phase compositions using a mesh target

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013093517A1 (en) * 2011-12-23 2013-06-27 Micromass Uk Limited Interfacing capillary electrophoresis to a mass spectrometer via an impactor spray ionization source
WO2014064399A1 (en) * 2012-10-25 2014-05-01 Micromass Uk Limited Piezo-electric vibration on an in-source surface ionization structure to aid secondary droplet reduction

Also Published As

Publication number Publication date
GB2533184A (en) 2016-06-15
CN106663587A (zh) 2017-05-10
EP3183740A1 (en) 2017-06-28
US10262851B2 (en) 2019-04-16
EP3183740B1 (en) 2018-06-27
JP2017526131A (ja) 2017-09-07
JP7018416B2 (ja) 2022-02-10
GB2533184B (en) 2019-01-16
US20170263428A1 (en) 2017-09-14
WO2016027073A1 (en) 2016-02-25
JP2020024923A (ja) 2020-02-13
GB201514635D0 (en) 2015-09-30

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